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Overview

ID MAG03855
Name TH1_bin.23
Sample SMP0100
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family UBA5066
Genus DAOMFB01
Species
Assembly information
Completeness (%) 87.65
Contamination (%) 0.91
GC content (%) 71.0
N50 (bp) 13,422
Genome size (bp) 3,016,087

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2518

Gene name Description KEGG GOs EC E-value Score Sequence
TH1_k127_1002355_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1297.0
TH1_k127_1002355_1 PFAM ribonuclease II K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 608.0
TH1_k127_1002355_10 required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000007863 264.0
TH1_k127_1002355_11 Tetratricopeptide repeat - - - 0.0000000000000000000000009378 116.0
TH1_k127_1002355_12 - - - - 0.000000000000000000005855 98.0
TH1_k127_1002355_13 Transcriptional regulator - - - 0.00005347 56.0
TH1_k127_1002355_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 584.0
TH1_k127_1002355_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 536.0
TH1_k127_1002355_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 546.0
TH1_k127_1002355_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 342.0
TH1_k127_1002355_6 peptidase M24 K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 348.0
TH1_k127_1002355_7 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 322.0
TH1_k127_1002355_8 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 299.0
TH1_k127_1002355_9 PFAM NHL repeat containing protein K13735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004353 295.0
TH1_k127_1020814_0 Surface antigen variable number - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007833 289.0
TH1_k127_1020814_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000002432 147.0
TH1_k127_1021227_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 555.0
TH1_k127_1021227_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 349.0
TH1_k127_1021227_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 315.0
TH1_k127_1021227_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000002962 280.0
TH1_k127_1021227_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000004727 251.0
TH1_k127_1021227_5 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000001518 187.0
TH1_k127_1021227_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000001096 113.0
TH1_k127_1021227_7 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000006018 102.0
TH1_k127_1021227_8 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000002659 97.0
TH1_k127_1021227_9 Ribosomal L32p protein family K02911 - - 0.0000000000000000006486 87.0
TH1_k127_1033825_0 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005548 257.0
TH1_k127_1033825_1 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000005277 97.0
TH1_k127_1048316_0 Prolyl oligopeptidase K01322 - 3.4.21.26 9.312e-237 752.0
TH1_k127_1048316_1 Tetratricopeptide repeat - - - 0.0000000000001871 80.0
TH1_k127_107421_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 291.0
TH1_k127_107421_1 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000001191 245.0
TH1_k127_107421_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000005886 117.0
TH1_k127_107421_3 COG Signal transduction mechanisms K18144 - - 0.00000000001157 72.0
TH1_k127_118764_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 404.0
TH1_k127_118764_1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 347.0
TH1_k127_118953_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000001471 235.0
TH1_k127_118953_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000006051 178.0
TH1_k127_118953_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000001065 133.0
TH1_k127_118953_3 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000187 110.0
TH1_k127_118953_4 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000002916 106.0
TH1_k127_118953_5 PASTA K12132 - 2.7.11.1 0.000000000000002758 85.0
TH1_k127_118953_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000001161 66.0
TH1_k127_118953_7 Flagellar Motor Protein K02557 - - 0.000001354 59.0
TH1_k127_118953_8 PFAM helix-turn-helix, Fis-type - - - 0.000002919 57.0
TH1_k127_1194004_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.778e-237 755.0
TH1_k127_1194004_1 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K01782,K01825 GO:0003674,GO:0003824,GO:0003857,GO:0004165,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 1.215e-211 670.0
TH1_k127_1194004_2 Transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000004068 197.0
TH1_k127_1194004_3 Dodecin K09165 - - 0.00000000000000000000001789 101.0
TH1_k127_1194004_4 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000001194 75.0
TH1_k127_1233873_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000008199 272.0
TH1_k127_1233873_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001156 243.0
TH1_k127_1233873_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000002062 231.0
TH1_k127_1233873_3 phosphatase activity K07025,K20862 - 3.1.3.102,3.1.3.104 0.00000000000000000001879 108.0
TH1_k127_1233873_4 membrane K07058 - - 0.000000000002367 80.0
TH1_k127_1233873_5 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000006298 53.0
TH1_k127_1233873_6 Bacterial protein of unknown function (DUF883) - GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0043021,GO:0043024,GO:0044464,GO:0044877,GO:0060187,GO:0071944 - 0.00003576 52.0
TH1_k127_1274725_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 403.0
TH1_k127_1274725_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000001708 224.0
TH1_k127_1274725_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000002693 203.0
TH1_k127_1274725_3 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000000000001543 154.0
TH1_k127_1274725_4 - - - - 0.0000000000002388 83.0
TH1_k127_1375670_0 ABC-type multidrug transport system, ATPase and permease K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 429.0
TH1_k127_1375670_1 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000161 232.0
TH1_k127_1375670_2 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000002994 195.0
TH1_k127_1375670_3 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000002862 186.0
TH1_k127_1375670_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000001359 60.0
TH1_k127_1375670_5 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0001219 48.0
TH1_k127_1398651_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1206.0
TH1_k127_1398651_1 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 450.0
TH1_k127_1398651_2 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 310.0
TH1_k127_1398651_3 PFAM peptidase T2 asparaginase 2 K01444,K13051 - 3.4.19.5,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 315.0
TH1_k127_1398651_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005833 291.0
TH1_k127_1398651_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000055 233.0
TH1_k127_1398651_6 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000000000052 207.0
TH1_k127_1398651_7 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000001053 147.0
TH1_k127_1398651_8 - - - - 0.00000000001467 71.0
TH1_k127_1399008_0 Prolyl oligopeptidase family - - - 3.297e-224 715.0
TH1_k127_1399008_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009722 544.0
TH1_k127_1399008_2 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 544.0
TH1_k127_1399008_3 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 343.0
TH1_k127_1399008_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000004466 259.0
TH1_k127_1399008_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000001615 228.0
TH1_k127_1399008_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000237 141.0
TH1_k127_1399008_7 HlyD family secretion protein K02005 - - 0.000000000000000000000000000007943 138.0
TH1_k127_1399008_8 COG1566 Multidrug resistance efflux pump - - - 0.0000000000001304 85.0
TH1_k127_1399008_9 - - - - 0.00002597 51.0
TH1_k127_1399695_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 4.073e-250 807.0
TH1_k127_1399695_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 419.0
TH1_k127_1399695_10 TIGRFAM TonB family K03832 - - 0.0000000000002988 75.0
TH1_k127_1399695_11 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0000000000007998 82.0
TH1_k127_1399695_12 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000194 59.0
TH1_k127_1399695_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 335.0
TH1_k127_1399695_3 PFAM PfkB domain protein K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 323.0
TH1_k127_1399695_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002693 270.0
TH1_k127_1399695_5 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000941 259.0
TH1_k127_1399695_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000013 193.0
TH1_k127_1399695_7 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000009971 149.0
TH1_k127_1399695_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000006396 131.0
TH1_k127_1399695_9 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000008661 115.0
TH1_k127_1447899_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 530.0
TH1_k127_1447899_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000005482 241.0
TH1_k127_1447899_2 - - - - 0.00000000000000000000000000000000000000005377 163.0
TH1_k127_1447899_3 CoA binding domain - - - 0.000000000000000000000000000000002271 139.0
TH1_k127_1447899_4 Outer membrane efflux protein - - - 0.000186 48.0
TH1_k127_1528611_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 356.0
TH1_k127_1528611_1 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007684 259.0
TH1_k127_1528611_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000002303 102.0
TH1_k127_1528611_11 STAS domain - - - 0.00000000000000513 81.0
TH1_k127_1528611_2 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000003568 256.0
TH1_k127_1528611_3 Amidohydrolase family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000001533 219.0
TH1_k127_1528611_4 metallopeptidase activity K01993,K13408,K16922 - - 0.0000000000000000000000000000000000000000000000000000000002042 234.0
TH1_k127_1528611_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.000000000000000000000000000000000000000000000000001336 208.0
TH1_k127_1528611_6 N-acetylglucosamine kinase activity K00884 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 2.7.1.59 0.000000000000000000000000000000000000428 151.0
TH1_k127_1528611_7 Histidine kinase - - - 0.000000000000000000000000001568 124.0
TH1_k127_1528611_8 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.00000000000000000000000004716 124.0
TH1_k127_1528611_9 Beta-lactamase enzyme family K07258,K17836 - 3.4.16.4,3.5.2.6 0.00000000000000000000000008341 123.0
TH1_k127_154732_0 Sodium Bile acid symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 486.0
TH1_k127_154732_1 permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 465.0
TH1_k127_154732_10 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000002918 163.0
TH1_k127_154732_11 SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000003196 153.0
TH1_k127_154732_12 helix_turn_helix, Arsenical Resistance Operon Repressor K03892,K21903 - - 0.000000000000000000000000001232 116.0
TH1_k127_154732_13 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000002057 117.0
TH1_k127_154732_14 redox-active disulfide protein 2 - - - 0.0000000000000001539 90.0
TH1_k127_154732_15 dipeptidyl-peptidase activity - - - 0.00000000000007803 85.0
TH1_k127_154732_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 403.0
TH1_k127_154732_3 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 363.0
TH1_k127_154732_4 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 338.0
TH1_k127_154732_5 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 348.0
TH1_k127_154732_7 coagulation factor 5 8 type - - - 0.000000000000000000000000000000000000000000000000000146 201.0
TH1_k127_154732_8 AAA domain - - - 0.0000000000000000000000000000000000000000000000000008346 194.0
TH1_k127_154732_9 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000126 168.0
TH1_k127_1597868_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 415.0
TH1_k127_1597868_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 355.0
TH1_k127_1597868_10 gluconolactonase activity K21449 - - 0.00000000000000005817 97.0
TH1_k127_1597868_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 347.0
TH1_k127_1597868_3 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 344.0
TH1_k127_1597868_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639,K20967 - 4.1.99.22,4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000004021 274.0
TH1_k127_1597868_5 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000003869 201.0
TH1_k127_1597868_6 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000003546 171.0
TH1_k127_1597868_7 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000002149 176.0
TH1_k127_1597868_8 Stage II sporulation D domain protein K06381 - - 0.000000000000000000000000000000002703 141.0
TH1_k127_1597868_9 Peptidase family C25 - - - 0.00000000000000000006023 107.0
TH1_k127_1616698_0 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 596.0
TH1_k127_1616698_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 554.0
TH1_k127_1616698_10 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000006908 217.0
TH1_k127_1616698_11 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000001053 185.0
TH1_k127_1616698_12 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000002962 195.0
TH1_k127_1616698_13 Histidine kinase HAMP - - - 0.00000000000000000000000000000000000000000003704 179.0
TH1_k127_1616698_14 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000005752 170.0
TH1_k127_1616698_15 NHL repeat containing protein - - - 0.000000000000000000000000000000000000000198 174.0
TH1_k127_1616698_16 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000004235 157.0
TH1_k127_1616698_17 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.0000000000000000000000000000002621 140.0
TH1_k127_1616698_18 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000001176 132.0
TH1_k127_1616698_2 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 406.0
TH1_k127_1616698_20 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.0000000000000003183 90.0
TH1_k127_1616698_21 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000006372 69.0
TH1_k127_1616698_22 NHL repeat - - - 0.0000005317 64.0
TH1_k127_1616698_23 cellulase activity K01727 - 4.2.2.1 0.000002989 62.0
TH1_k127_1616698_24 Cytochrome c biogenesis protein K07399 - - 0.00003623 56.0
TH1_k127_1616698_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 382.0
TH1_k127_1616698_4 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 364.0
TH1_k127_1616698_5 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 353.0
TH1_k127_1616698_6 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 317.0
TH1_k127_1616698_7 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004697 280.0
TH1_k127_1616698_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004531 286.0
TH1_k127_1616698_9 cellulase activity K01727 - 4.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000008724 252.0
TH1_k127_1668042_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.00000000000000000000000000000000000000000000000000000001199 213.0
TH1_k127_1668042_1 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000008051 109.0
TH1_k127_1668042_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000001289 113.0
TH1_k127_1668042_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000001785 105.0
TH1_k127_1669634_0 Site-specific recombinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 491.0
TH1_k127_1669634_1 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 370.0
TH1_k127_1669634_2 Mechanosensitive ion channel K16052,K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 321.0
TH1_k127_1669634_3 PFAM glycosyl transferase family 39 K14340 - - 0.0000000000000000000000000000000000000000000002857 191.0
TH1_k127_1669634_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000001085 187.0
TH1_k127_1669634_5 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000001018 126.0
TH1_k127_1684502_0 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 355.0
TH1_k127_1684502_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000009722 219.0
TH1_k127_1684502_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000001845 116.0
TH1_k127_1684502_3 nuclear chromosome segregation - - - 0.000000000000000006591 98.0
TH1_k127_1910112_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.433e-210 676.0
TH1_k127_1910112_1 Belongs to the Orn Lys Arg decarboxylase class-II family K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000001214 259.0
TH1_k127_1910112_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000005768 182.0
TH1_k127_192787_0 PFAM Prolyl oligopeptidase family - - - 7.766e-244 769.0
TH1_k127_192787_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 385.0
TH1_k127_192787_2 imidazolonepropionase activity K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000002094 285.0
TH1_k127_192787_3 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000004054 175.0
TH1_k127_192787_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.00000000000000000000005995 115.0
TH1_k127_1961185_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 306.0
TH1_k127_1961185_1 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000001613 239.0
TH1_k127_1961185_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000003139 168.0
TH1_k127_1961185_3 spore germination - - - 0.00000000000000000000009663 109.0
TH1_k127_1961185_4 Domain of unknown function (DUF4340) - - - 0.0001036 55.0
TH1_k127_1975415_0 Large extracellular alpha-helical protein - - - 0.0 2185.0
TH1_k127_1975415_1 Zinc carboxypeptidase K14054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 474.0
TH1_k127_1975415_2 RNA polymerase recycling family C-terminal K03580 - - 0.0000002642 58.0
TH1_k127_1980308_0 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 298.0
TH1_k127_1980308_1 Hydroxypyruvate reductase K11529 - 2.7.1.165 0.0000000000000000000000000000000004132 141.0
TH1_k127_207538_0 transcriptional regulator K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 376.0
TH1_k127_207538_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000002164 226.0
TH1_k127_2077682_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 6.339e-309 985.0
TH1_k127_2077682_1 GMP synthase (glutamine-hydrolyzing) activity K01951,K03790 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 580.0
TH1_k127_2077682_10 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000003046 90.0
TH1_k127_2077682_11 - - - - 0.00000000000004009 82.0
TH1_k127_2077682_2 Putative Na+/H+ antiporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 576.0
TH1_k127_2077682_3 Proline racemase K12658 - 5.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 363.0
TH1_k127_2077682_4 Belongs to the DapA family K21062 - 3.5.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 379.0
TH1_k127_2077682_5 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005838 379.0
TH1_k127_2077682_6 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009062 355.0
TH1_k127_2077682_7 Belongs to the aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000000000000000000000000000000000006261 201.0
TH1_k127_2077682_8 lytic transglycosylase - - - 0.000000000000000000000000000000000002594 146.0
TH1_k127_2077682_9 Poly A polymerase head domain - - - 0.0000000000000000000000000000001099 146.0
TH1_k127_2092102_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.109e-207 667.0
TH1_k127_2092102_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 400.0
TH1_k127_2092102_2 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008275 293.0
TH1_k127_2092102_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000003642 218.0
TH1_k127_2092102_4 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000005592 151.0
TH1_k127_2113367_0 phosphorelay signal transduction system - - - 0.000000000000000000000000101 118.0
TH1_k127_2114902_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 427.0
TH1_k127_2114902_1 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 371.0
TH1_k127_2114902_2 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 340.0
TH1_k127_2114902_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 304.0
TH1_k127_2114902_4 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000002165 218.0
TH1_k127_2114902_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000004459 229.0
TH1_k127_2114902_6 PFAM PKD domain containing protein - - - 0.00000000000002057 87.0
TH1_k127_212252_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 404.0
TH1_k127_212252_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 357.0
TH1_k127_212252_2 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 315.0
TH1_k127_212252_3 ABC transporter, (ATP-binding protein) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 307.0
TH1_k127_212252_4 Beta-lactamase class A K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000005207 207.0
TH1_k127_212252_5 Transcriptional regulator K07735 - - 0.000000000000000000000002013 119.0
TH1_k127_212252_6 OsmC-like protein - - - 0.00000000000000000000004649 103.0
TH1_k127_2254476_0 Predicted Permease Membrane Region - - - 6.415e-207 657.0
TH1_k127_2254476_1 Glycogen debranching enzyme - - - 7.431e-197 619.0
TH1_k127_2254476_2 Inorganic ion transport and metabolism K03319 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 509.0
TH1_k127_2254476_3 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 429.0
TH1_k127_2254476_4 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 386.0
TH1_k127_2254476_5 UPF0126 domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000001318 207.0
TH1_k127_2254476_7 - - - - 0.000000000000000000000002394 110.0
TH1_k127_2268625_0 DNA photolyase domain protein K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 374.0
TH1_k127_2268625_1 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000002447 139.0
TH1_k127_2268625_2 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000002824 137.0
TH1_k127_2279990_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1570.0
TH1_k127_2279990_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 1.107e-203 648.0
TH1_k127_2279990_10 Major royal jelly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 338.0
TH1_k127_2279990_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 299.0
TH1_k127_2279990_13 MobA-like NTP transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 300.0
TH1_k127_2279990_14 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000113 274.0
TH1_k127_2279990_15 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000003109 198.0
TH1_k127_2279990_16 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000003228 200.0
TH1_k127_2279990_17 PAP2 superfamily C-terminal - - - 0.000000000000000000000000000000000000000000128 179.0
TH1_k127_2279990_18 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000002249 165.0
TH1_k127_2279990_19 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000001668 161.0
TH1_k127_2279990_2 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 589.0
TH1_k127_2279990_20 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000000000000000000000000000000000001388 153.0
TH1_k127_2279990_21 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000002686 152.0
TH1_k127_2279990_22 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000005887 127.0
TH1_k127_2279990_23 Hfq protein - - - 0.000000000000000000000000000002429 126.0
TH1_k127_2279990_24 - - - - 0.0000000000000000000000000001413 128.0
TH1_k127_2279990_25 Male sterility protein - - - 0.000000000000000003626 100.0
TH1_k127_2279990_26 DinB superfamily - - - 0.00000001049 68.0
TH1_k127_2279990_27 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00001279 58.0
TH1_k127_2279990_28 PA14 - - - 0.00003596 56.0
TH1_k127_2279990_29 Bacterial transcriptional activator domain - - - 0.0002144 53.0
TH1_k127_2279990_3 peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 526.0
TH1_k127_2279990_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 499.0
TH1_k127_2279990_5 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 466.0
TH1_k127_2279990_6 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 439.0
TH1_k127_2279990_7 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 384.0
TH1_k127_2279990_8 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 365.0
TH1_k127_2279990_9 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 354.0
TH1_k127_2283421_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.727e-218 696.0
TH1_k127_2283421_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001511 256.0
TH1_k127_2304943_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002937 281.0
TH1_k127_2304943_1 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000000000001115 189.0
TH1_k127_2304943_2 - K01992,K19341 - - 0.000000000000000000000000000000000000002855 164.0
TH1_k127_2304943_3 Domain of unknown function (DUF4136) - - - 0.000000000000000000001761 101.0
TH1_k127_2304943_5 palmitoyl-(protein) hydrolase activity K06999 - - 0.0000001732 64.0
TH1_k127_2309481_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 532.0
TH1_k127_2309481_1 Amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 319.0
TH1_k127_2309481_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000005988 128.0
TH1_k127_2309481_3 Major facilitator K08223 - - 0.00000000000000007652 93.0
TH1_k127_2313089_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 433.0
TH1_k127_2313089_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 362.0
TH1_k127_2313089_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 340.0
TH1_k127_2313089_3 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000007102 170.0
TH1_k127_2313089_4 - - - - 0.00000000000002363 78.0
TH1_k127_2313089_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0005125 49.0
TH1_k127_2315374_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 5.832e-224 709.0
TH1_k127_2315374_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 6.783e-222 695.0
TH1_k127_2315374_10 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000002555 227.0
TH1_k127_2315374_11 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000006279 203.0
TH1_k127_2315374_12 lipopolysaccharide 3-alpha-galactosyltransferase activity - - - 0.000000000000000000000000000000000000000002162 175.0
TH1_k127_2315374_13 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000005131 158.0
TH1_k127_2315374_14 metalloendopeptidase activity K03799 - - 0.00000000000000000000000000000000000007772 161.0
TH1_k127_2315374_15 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000007687 115.0
TH1_k127_2315374_18 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000001161 71.0
TH1_k127_2315374_2 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 657.0
TH1_k127_2315374_20 LTXXQ motif family protein - - - 0.00007225 51.0
TH1_k127_2315374_3 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 407.0
TH1_k127_2315374_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 345.0
TH1_k127_2315374_5 epimerase dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 317.0
TH1_k127_2315374_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 305.0
TH1_k127_2315374_7 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001834 291.0
TH1_k127_2315374_8 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005011 277.0
TH1_k127_2315374_9 COG3959 Transketolase, N-terminal subunit K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000245 276.0
TH1_k127_2329038_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 388.0
TH1_k127_2329038_1 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.00000000000000000000000000000000000000000000000000000000000003981 241.0
TH1_k127_2329038_2 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000001566 168.0
TH1_k127_2329038_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. K07636 - 2.7.13.3 0.0000000000000000000000238 115.0
TH1_k127_2342198_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 404.0
TH1_k127_2342198_1 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 400.0
TH1_k127_2342198_11 PFAM RDD domain containing protein - - - 0.00002631 57.0
TH1_k127_2342198_12 Belongs to the BshC family K22136 - - 0.00008087 49.0
TH1_k127_2342198_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 316.0
TH1_k127_2342198_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000003173 203.0
TH1_k127_2342198_4 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000005299 197.0
TH1_k127_2342198_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000001118 202.0
TH1_k127_2342198_6 PFAM adenosine AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000001343 198.0
TH1_k127_2342198_7 - - - - 0.000000000000003633 88.0
TH1_k127_2342198_8 Preprotein translocase SecG subunit K03075 - - 0.00000000000003544 81.0
TH1_k127_2342198_9 Domain of unknown function (DUF4870) - - - 0.00000003922 61.0
TH1_k127_2367601_0 transcription factor binding K02584 - - 5.809e-199 632.0
TH1_k127_2367601_1 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 557.0
TH1_k127_2367601_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 481.0
TH1_k127_2367601_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 431.0
TH1_k127_2367601_4 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 428.0
TH1_k127_2367601_5 Dna alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000007664 232.0
TH1_k127_2367601_6 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000000007719 207.0
TH1_k127_2367601_7 DinB family - - - 0.00000000000000000000000000000000000001918 166.0
TH1_k127_2367601_8 TIGRFAM ribonuclease BN K07058 - - 0.00000000000000007725 91.0
TH1_k127_238066_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 532.0
TH1_k127_238066_1 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 357.0
TH1_k127_238066_10 Eukaryotic integral membrane protein (DUF1751) - - - 0.0000000000002074 80.0
TH1_k127_238066_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000006943 78.0
TH1_k127_238066_12 DivIVA domain protein K04074 - - 0.0000000006536 71.0
TH1_k127_238066_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004644 277.0
TH1_k127_238066_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000007606 196.0
TH1_k127_238066_4 Histidinol phosphatase and related hydrolases of the PHP family K04477 - - 0.00000000000000000000000000000000000000000000006954 184.0
TH1_k127_238066_5 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000000000000001564 152.0
TH1_k127_238066_6 Reverse transcriptase-like K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.00000000000000000000004015 105.0
TH1_k127_238066_7 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000000000000000001467 103.0
TH1_k127_238066_8 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000002222 90.0
TH1_k127_238066_9 C4-type zinc ribbon domain K07164 - - 0.000000000000003836 86.0
TH1_k127_2385024_0 Tricorn protease homolog K08676 - - 0.0 1047.0
TH1_k127_2385024_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 5.988e-231 731.0
TH1_k127_2385024_2 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 508.0
TH1_k127_2385024_3 IgA Peptidase M64 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 492.0
TH1_k127_2385024_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 361.0
TH1_k127_2385024_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000005593 141.0
TH1_k127_2385024_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000002169 110.0
TH1_k127_2470224_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.115e-274 863.0
TH1_k127_2470224_1 DEAD DEAH box helicase - - - 4.05e-260 827.0
TH1_k127_2470224_10 MlaD protein K02067 - - 0.000000000000000000000000000000000002634 153.0
TH1_k127_2470224_11 acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000004771 143.0
TH1_k127_2470224_12 NAD dependent epimerase dehydratase K08679 - 5.1.3.6 0.00000000000008728 83.0
TH1_k127_2470224_13 Outer membrane efflux protein - - - 0.000000000004494 78.0
TH1_k127_2470224_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 482.0
TH1_k127_2470224_3 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 475.0
TH1_k127_2470224_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 352.0
TH1_k127_2470224_5 PFAM Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001516 274.0
TH1_k127_2470224_6 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000006212 237.0
TH1_k127_2470224_7 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000003101 253.0
TH1_k127_2470224_8 - - - - 0.0000000000000000000000000000000000000000006934 161.0
TH1_k127_2470224_9 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000001579 169.0
TH1_k127_2477464_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 8.545e-196 623.0
TH1_k127_2477464_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 534.0
TH1_k127_2477464_10 oxidoreductase activity - - - 0.0000000003858 73.0
TH1_k127_2477464_2 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 434.0
TH1_k127_2477464_3 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 420.0
TH1_k127_2477464_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 377.0
TH1_k127_2477464_5 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007345 290.0
TH1_k127_2477464_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000003466 250.0
TH1_k127_2477464_7 PFAM Thymidine kinase K00857 - 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000001671 239.0
TH1_k127_2477464_8 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000409 80.0
TH1_k127_2477464_9 chaperone-mediated protein folding - - - 0.0000000001804 74.0
TH1_k127_2489776_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 6.901e-314 986.0
TH1_k127_2489776_1 Carbamoyltransferase C-terminus K00612 - - 1.847e-257 808.0
TH1_k127_2489776_10 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000951 68.0
TH1_k127_2489776_12 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000085 64.0
TH1_k127_2489776_13 - - - - 0.00006235 51.0
TH1_k127_2489776_2 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 6.814e-227 707.0
TH1_k127_2489776_3 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 420.0
TH1_k127_2489776_4 TIGRFAM channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000021 267.0
TH1_k127_2489776_5 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000006917 187.0
TH1_k127_2489776_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000001493 199.0
TH1_k127_2489776_7 Acyltransferase - - - 0.0000000000000000000000000000000000001894 161.0
TH1_k127_2489776_8 lipolytic protein G-D-S-L family - - - 0.000000000001309 79.0
TH1_k127_2489776_9 - - - - 0.00000000006874 63.0
TH1_k127_2494361_0 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 485.0
TH1_k127_2494361_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 443.0
TH1_k127_2494361_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 411.0
TH1_k127_2494361_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 392.0
TH1_k127_2494361_4 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 378.0
TH1_k127_2494361_5 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000006726 170.0
TH1_k127_2515027_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 340.0
TH1_k127_2515027_1 Spore Coat K01790 - 5.1.3.13 0.0000000000000000000000000001616 122.0
TH1_k127_2515027_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000002849 83.0
TH1_k127_2515027_3 Forkhead associated domain - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.000000000001407 77.0
TH1_k127_2515027_4 Transcriptional regulatory protein, C terminal - - - 0.00000000001561 74.0
TH1_k127_2554894_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005773 253.0
TH1_k127_2554894_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000003377 223.0
TH1_k127_2554894_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000004263 131.0
TH1_k127_2554894_3 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.0000001384 63.0
TH1_k127_2560262_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 522.0
TH1_k127_2560262_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000008277 239.0
TH1_k127_2560262_2 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000001427 139.0
TH1_k127_2560262_3 AsnC family - - - 0.0000000000000000000000000000001377 129.0
TH1_k127_2560262_4 FG-GAP repeat - - - 0.000000000007814 78.0
TH1_k127_2560262_5 Helix-turn-helix - - - 0.00000005989 60.0
TH1_k127_2560344_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 527.0
TH1_k127_2560344_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 472.0
TH1_k127_2560344_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 323.0
TH1_k127_2560344_3 Magnesium transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000000000000000000003874 242.0
TH1_k127_2560344_4 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000004477 173.0
TH1_k127_2560344_5 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000003291 144.0
TH1_k127_2560344_6 chaperone-mediated protein folding - - - 0.0000000000008219 83.0
TH1_k127_2560344_7 histone H2A K63-linked ubiquitination - - - 0.0000001276 60.0
TH1_k127_2616282_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 548.0
TH1_k127_2616282_1 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 403.0
TH1_k127_2616282_2 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 389.0
TH1_k127_2616282_3 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 334.0
TH1_k127_2616282_4 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002938 272.0
TH1_k127_2616282_5 Phage integrase, N-terminal SAM-like domain K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004248 275.0
TH1_k127_2616282_6 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003342 275.0
TH1_k127_2616282_7 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000183 237.0
TH1_k127_2616282_8 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000003237 197.0
TH1_k127_2616282_9 DinB family - - - 0.0000000000000000000000000000000005788 152.0
TH1_k127_2617547_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 314.0
TH1_k127_2617547_1 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000000000002464 192.0
TH1_k127_2617547_2 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.000000000000000000000000000000000002848 158.0
TH1_k127_2644673_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 501.0
TH1_k127_2644673_1 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 384.0
TH1_k127_2644673_2 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000102 266.0
TH1_k127_2644673_3 Proteasome subunit K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000005319 226.0
TH1_k127_2644673_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000002522 183.0
TH1_k127_2644673_5 Fibronectin, type III domain - - - 0.00000000000000009298 95.0
TH1_k127_2644673_6 Protein of unknown function (DUF1573) - - - 0.000000000001649 79.0
TH1_k127_2644673_7 Bacterial regulatory proteins, tetR family - - - 0.000000000003752 78.0
TH1_k127_2653399_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1695.0
TH1_k127_2653399_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 599.0
TH1_k127_2653399_10 PFAM Ion transport 2 domain protein - - - 0.000000000000000000000000000000000000000000003981 172.0
TH1_k127_2653399_11 diguanylate cyclase - - - 0.0000000000000000000000000000005426 136.0
TH1_k127_2653399_12 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.000000000000000000000000004412 116.0
TH1_k127_2653399_13 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000008225 117.0
TH1_k127_2653399_14 signal transduction histidine kinase K07642 - 2.7.13.3 0.000000000000000000000000691 118.0
TH1_k127_2653399_15 - - - - 0.0000000000000000000002293 103.0
TH1_k127_2653399_16 Protease prsW family - - - 0.00000004077 66.0
TH1_k127_2653399_17 - - - - 0.00002533 48.0
TH1_k127_2653399_18 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00005568 52.0
TH1_k127_2653399_19 Domain of unknown function (DUF4339) - - - 0.0002329 53.0
TH1_k127_2653399_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 580.0
TH1_k127_2653399_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 541.0
TH1_k127_2653399_4 HlyD membrane-fusion protein of T1SS K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 473.0
TH1_k127_2653399_5 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 425.0
TH1_k127_2653399_6 Acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 312.0
TH1_k127_2653399_7 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003416 253.0
TH1_k127_2653399_8 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000000002905 211.0
TH1_k127_2653399_9 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000101 177.0
TH1_k127_2708634_0 PFAM FAD dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001567 295.0
TH1_k127_2708634_1 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.00000000001637 77.0
TH1_k127_2717081_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 2.327e-250 782.0
TH1_k127_2717081_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.203e-247 780.0
TH1_k127_2717081_10 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 390.0
TH1_k127_2717081_11 With LivFGHM is involved in the high affinity leucine transport K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 372.0
TH1_k127_2717081_12 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 356.0
TH1_k127_2717081_13 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 334.0
TH1_k127_2717081_14 Binding-protein-dependent transport system inner membrane component K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 313.0
TH1_k127_2717081_15 sulfate ABC transporter K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 315.0
TH1_k127_2717081_16 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000002254 231.0
TH1_k127_2717081_17 Ferredoxin - - - 0.00000000000000000000000000000000000000000001375 171.0
TH1_k127_2717081_18 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000001005 177.0
TH1_k127_2717081_19 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000001605 164.0
TH1_k127_2717081_2 PFAM short-chain dehydrogenase reductase SDR K15314 - - 4.901e-236 762.0
TH1_k127_2717081_20 Sulfatase - - - 0.00000000000000000000000000000000003899 155.0
TH1_k127_2717081_21 COGs COG3603 conserved K09707 - - 0.0000000000000000000000000000000000816 140.0
TH1_k127_2717081_22 PFAM tRNA-hydroxylase K06169 - - 0.000000000000000000000000001505 129.0
TH1_k127_2717081_23 Transcriptional regulator - - - 0.000000000000000000000000004589 116.0
TH1_k127_2717081_24 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000008666 116.0
TH1_k127_2717081_25 - - - - 0.000000000000000000000202 113.0
TH1_k127_2717081_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.711e-214 689.0
TH1_k127_2717081_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 618.0
TH1_k127_2717081_5 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 548.0
TH1_k127_2717081_6 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 482.0
TH1_k127_2717081_7 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 439.0
TH1_k127_2717081_8 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 429.0
TH1_k127_2717081_9 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 404.0
TH1_k127_2745630_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 504.0
TH1_k127_2745630_1 BPG-independent PGAM N-terminus (iPGM_N) K15633 - 5.4.2.12 0.00000000000002752 74.0
TH1_k127_2745630_2 PFAM GCN5-related N-acetyltransferase - - - 0.0000000006552 70.0
TH1_k127_2760587_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.237e-288 912.0
TH1_k127_2760587_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.972e-248 789.0
TH1_k127_2760587_10 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.0000000000000000000000000000000000000004954 167.0
TH1_k127_2760587_11 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000003869 122.0
TH1_k127_2760587_12 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000544 120.0
TH1_k127_2760587_13 cellular component assembly - - - 0.00000000000000000000000006478 126.0
TH1_k127_2760587_14 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000001807 119.0
TH1_k127_2760587_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.00000000000001168 78.0
TH1_k127_2760587_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000004897 76.0
TH1_k127_2760587_17 COGs COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains K06714,K21405 - - 0.00000698 50.0
TH1_k127_2760587_18 protein conserved in bacteria K09928 - - 0.0001873 51.0
TH1_k127_2760587_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.004e-219 691.0
TH1_k127_2760587_3 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 417.0
TH1_k127_2760587_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 376.0
TH1_k127_2760587_5 PFAM Binding-protein-dependent transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 297.0
TH1_k127_2760587_6 PFAM Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003345 261.0
TH1_k127_2760587_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000004359 217.0
TH1_k127_2760587_8 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000002858 213.0
TH1_k127_2760587_9 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000322 186.0
TH1_k127_2776593_0 Molybdate transporter of MFS superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 516.0
TH1_k127_2776593_1 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000009142 196.0
TH1_k127_2776593_2 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000008565 193.0
TH1_k127_2777419_0 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000361 199.0
TH1_k127_2777419_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000451 143.0
TH1_k127_281117_0 Cytochrome bd terminal oxidase subunit I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 345.0
TH1_k127_281117_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 304.0
TH1_k127_281117_2 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002991 248.0
TH1_k127_281117_3 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000238 175.0
TH1_k127_281117_4 chlorophyll binding - - - 0.00000000000000000000000000000000000000005673 171.0
TH1_k127_281117_5 ribonuclease - - - 0.00000000000000000000000000000003343 132.0
TH1_k127_281117_6 oxidase subunit K08738 - - 0.0000000000000000000000000000001815 137.0
TH1_k127_281117_7 Barstar (barnase inhibitor) - - - 0.00000000000000000004006 101.0
TH1_k127_2827774_0 Polyphosphate kinase middle domain K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 603.0
TH1_k127_2827774_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 438.0
TH1_k127_2827774_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000453 265.0
TH1_k127_2827774_3 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001831 273.0
TH1_k127_2827774_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000009085 195.0
TH1_k127_2827774_5 PFAM CHAD domain containing protein - - - 0.0000004409 64.0
TH1_k127_2828929_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 348.0
TH1_k127_2828929_1 curli production assembly transport component CsgG - - - 0.00000000000000000000001401 111.0
TH1_k127_2828929_2 Smr domain - - - 0.0000000000000000000001796 102.0
TH1_k127_2846065_0 Sulfatase K01130 - 3.1.6.1 0.0 1433.0
TH1_k127_2846065_1 Peptidase S46 - - - 2.986e-289 924.0
TH1_k127_2846065_10 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 437.0
TH1_k127_2846065_11 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 391.0
TH1_k127_2846065_12 virion core protein (lumpy skin disease virus) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 343.0
TH1_k127_2846065_13 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 314.0
TH1_k127_2846065_14 tRNA wobble cytosine modification - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 296.0
TH1_k127_2846065_15 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000006336 282.0
TH1_k127_2846065_16 periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001256 264.0
TH1_k127_2846065_17 Belongs to the SEDS family K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000001926 249.0
TH1_k127_2846065_18 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000001545 243.0
TH1_k127_2846065_19 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000004583 176.0
TH1_k127_2846065_2 Protein of unknown function (DUF1254) - - - 3.452e-244 764.0
TH1_k127_2846065_20 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000001241 154.0
TH1_k127_2846065_21 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000001103 139.0
TH1_k127_2846065_22 - - - - 0.000000000000000000000000005002 124.0
TH1_k127_2846065_23 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.0000000000000000000000002017 122.0
TH1_k127_2846065_24 Belongs to the universal stress protein A family - - - 0.0000000000000000000000007025 116.0
TH1_k127_2846065_25 - - - - 0.000000000000000000001069 110.0
TH1_k127_2846065_26 Peptidase family M28 - - - 0.00000000000000000001286 108.0
TH1_k127_2846065_27 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000003073 102.0
TH1_k127_2846065_28 - - - - 0.000000000000000445 89.0
TH1_k127_2846065_29 PFAM Diacylglycerol kinase, catalytic domain - - - 0.0000000000000008344 92.0
TH1_k127_2846065_3 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 614.0
TH1_k127_2846065_30 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000001205 85.0
TH1_k127_2846065_31 - - - - 0.00000000000000121 89.0
TH1_k127_2846065_32 Cbs domain K04767 - - 0.000000000000001453 83.0
TH1_k127_2846065_33 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000009815 79.0
TH1_k127_2846065_34 PFAM FecR protein - - - 0.000000001069 71.0
TH1_k127_2846065_4 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 601.0
TH1_k127_2846065_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 578.0
TH1_k127_2846065_6 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 534.0
TH1_k127_2846065_7 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 507.0
TH1_k127_2846065_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 424.0
TH1_k127_2846065_9 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 422.0
TH1_k127_2870154_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K17217 - 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 404.0
TH1_k127_2870154_1 Pyridoxal-phosphate dependent enzyme K01738,K17216 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 364.0
TH1_k127_2870154_2 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000002489 278.0
TH1_k127_2870154_3 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000001781 230.0
TH1_k127_2870154_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000615 149.0
TH1_k127_2870154_5 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000002058 129.0
TH1_k127_2870154_6 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000001712 131.0
TH1_k127_2870154_7 CYTH K05873 - 4.6.1.1 0.0000000000000001794 83.0
TH1_k127_2870154_8 Helix-hairpin-helix motif K02237 - - 0.0000000000000002374 86.0
TH1_k127_2870154_9 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000001074 68.0
TH1_k127_2914894_0 - - - - 0.0 1043.0
TH1_k127_2914894_1 Beta-eliminating lyase K01667,K01668 - 4.1.99.1,4.1.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 526.0
TH1_k127_2947152_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 445.0
TH1_k127_2947152_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009853 338.0
TH1_k127_2947152_2 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 321.0
TH1_k127_2947152_3 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006853 288.0
TH1_k127_2947152_4 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000002203 119.0
TH1_k127_2947152_5 TIGRFAM TonB family C-terminal domain K03832 - - 0.00000003014 66.0
TH1_k127_2947152_6 Thioredoxin-like - - - 0.00001179 52.0
TH1_k127_2960453_0 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 440.0
TH1_k127_2960453_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 423.0
TH1_k127_2960453_2 PFAM Formiminotransferase K00603 - 2.1.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 344.0
TH1_k127_2960453_3 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002188 280.0
TH1_k127_3031311_0 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 310.0
TH1_k127_3031311_1 ig-like, plexins, transcription factors - - - 0.0000000000000000000006484 112.0
TH1_k127_3031311_2 Tetratricopeptide repeat K00661,K18626 - 2.3.1.79 0.000000005722 68.0
TH1_k127_3033583_0 Malic enzyme, N-terminal domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 539.0
TH1_k127_3033583_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000068 253.0
TH1_k127_3033583_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000001349 215.0
TH1_k127_3033583_3 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000000001573 129.0
TH1_k127_3050940_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 341.0
TH1_k127_3050940_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000002647 102.0
TH1_k127_3064915_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 430.0
TH1_k127_3064915_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 406.0
TH1_k127_3064915_10 Protein of unknown function (DUF420) - - - 0.00000000000000000000000000000000003348 149.0
TH1_k127_3064915_11 Hpt domain - - - 0.0000000000000000000000000007175 126.0
TH1_k127_3064915_12 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000614 109.0
TH1_k127_3064915_13 - - - - 0.000000000000000000000209 100.0
TH1_k127_3064915_14 heme a metabolic process K02259,K03110 - - 0.000000000000000001066 102.0
TH1_k127_3064915_2 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 403.0
TH1_k127_3064915_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 334.0
TH1_k127_3064915_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003988 302.0
TH1_k127_3064915_5 PFAM Peptidase family M20 M25 M40 K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 291.0
TH1_k127_3064915_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000004144 224.0
TH1_k127_3064915_7 heme o metabolic process K02257,K09008,K22072 GO:0000266,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004311,GO:0004518,GO:0004519,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005829,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006753,GO:0006778,GO:0006779,GO:0006783,GO:0006784,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0008495,GO:0008535,GO:0009058,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009451,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016043,GO:0016070,GO:0016310,GO:0016740,GO:0016765,GO:0016787,GO:0016788,GO:0017004,GO:0017144,GO:0018130,GO:0018342,GO:0018343,GO:0019438,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032991,GO:0033013,GO:0033014,GO:0034622,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046148,GO:0046160,GO:0046483,GO:0048285,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0065003,GO:0070013,GO:0070069,GO:0071704,GO:0071840,GO:0072521,GO:0090304,GO:0090305,GO:0097159,GO:0097354,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000001451 186.0
TH1_k127_3064915_8 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000001263 168.0
TH1_k127_3064915_9 SCO1/SenC K07152 - - 0.00000000000000000000000000000000001474 153.0
TH1_k127_3068086_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 613.0
TH1_k127_3068086_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 355.0
TH1_k127_3068086_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 288.0
TH1_k127_3068086_3 LamB/YcsF family K07160 - - 0.00000000000000000000000000000000000000000000000000000000004179 226.0
TH1_k127_3068086_4 PFAM Allophanate hydrolase subunit 2 - - - 0.0000000000000000000000000000000000000000000000000000000001568 223.0
TH1_k127_3068086_5 beta-lactamase - - - 0.000000000000000000000000000000000000000000000002962 182.0
TH1_k127_3068086_6 allophanate hydrolase subunit 1 - - - 0.00000000000000000000000000000000000004699 164.0
TH1_k127_3068086_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000003357 87.0
TH1_k127_3087377_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 305.0
TH1_k127_3087377_1 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000004495 187.0
TH1_k127_3087377_10 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000001756 53.0
TH1_k127_3087377_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000006972 178.0
TH1_k127_3087377_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000001262 147.0
TH1_k127_3087377_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000402 143.0
TH1_k127_3087377_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000001717 133.0
TH1_k127_3087377_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000007071 76.0
TH1_k127_3087377_7 - - - - 0.0000001649 61.0
TH1_k127_3087377_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000002343 56.0
TH1_k127_3093127_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 472.0
TH1_k127_3093127_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000003551 165.0
TH1_k127_3093127_2 domain, Protein - - - 0.0000000000000000000000000000000001223 154.0
TH1_k127_3093127_3 HD domain - - - 0.0000000000000000000000009693 115.0
TH1_k127_3093448_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 558.0
TH1_k127_3093448_1 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 312.0
TH1_k127_3093448_2 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000001848 225.0
TH1_k127_3093448_3 Polymer-forming cytoskeletal - - - 0.00000000000000000001847 104.0
TH1_k127_3093448_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000001191 96.0
TH1_k127_3093448_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000335 82.0
TH1_k127_3093448_6 Putative zinc- or iron-chelating domain - - - 0.0000003407 57.0
TH1_k127_313378_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907,K01908 - 6.2.1.1,6.2.1.16,6.2.1.17 0.0 1068.0
TH1_k127_313378_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 433.0
TH1_k127_313378_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 305.0
TH1_k127_313378_3 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002674 273.0
TH1_k127_313378_4 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005001 277.0
TH1_k127_313378_5 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.0000000000000000000000000000000000000000000000000000005258 205.0
TH1_k127_313378_6 MFS/sugar transport protein K08223 - - 0.0000000000000000000000000000000000000000000000001647 186.0
TH1_k127_313378_7 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000003777 136.0
TH1_k127_314279_0 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 517.0
TH1_k127_314279_1 SMART PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 478.0
TH1_k127_314279_10 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000008433 145.0
TH1_k127_314279_11 Alpha beta hydrolase - - - 0.00000000000000000000000000007335 130.0
TH1_k127_314279_12 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000005534 96.0
TH1_k127_314279_13 - - - - 0.000000000000000005404 90.0
TH1_k127_314279_14 DNA-templated transcription, initiation K03088 - - 0.00008313 52.0
TH1_k127_314279_15 - - - - 0.0002798 43.0
TH1_k127_314279_2 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 416.0
TH1_k127_314279_3 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 386.0
TH1_k127_314279_4 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 340.0
TH1_k127_314279_5 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 329.0
TH1_k127_314279_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003669 304.0
TH1_k127_314279_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002088 284.0
TH1_k127_314279_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000001406 192.0
TH1_k127_314279_9 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000001357 169.0
TH1_k127_3165822_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1255.0
TH1_k127_3184766_0 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000001966 273.0
TH1_k127_3184766_1 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000132 162.0
TH1_k127_3192444_0 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 346.0
TH1_k127_3192444_1 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.00000000000000000000000000000000000001152 158.0
TH1_k127_3192444_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00006946 49.0
TH1_k127_3222679_0 ABC transporter transmembrane K11085 - - 2.347e-244 793.0
TH1_k127_3222679_1 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 517.0
TH1_k127_3222679_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000007977 176.0
TH1_k127_3222679_11 3-beta hydroxysteroid dehydrogenase isomerase K16045,K22320 GO:0000166,GO:0003674,GO:0003824,GO:0003854,GO:0004769,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016020,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016853,GO:0016860,GO:0016863,GO:0030283,GO:0033764,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901363 1.1.1.145,1.1.1.412,5.3.3.1 0.000000000000000000000002417 119.0
TH1_k127_3222679_12 Methyltransferase FkbM domain - - - 0.000000000001048 80.0
TH1_k127_3222679_13 PFAM conserved K07027 - - 0.0000000003449 73.0
TH1_k127_3222679_14 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.00000002937 67.0
TH1_k127_3222679_15 Methyltransferase domain - - - 0.000000641 63.0
TH1_k127_3222679_2 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 417.0
TH1_k127_3222679_3 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 385.0
TH1_k127_3222679_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 355.0
TH1_k127_3222679_5 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 328.0
TH1_k127_3222679_6 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000004985 204.0
TH1_k127_3222679_7 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000000000000009408 184.0
TH1_k127_3222679_8 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000218 182.0
TH1_k127_3222679_9 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000002544 187.0
TH1_k127_3252049_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 453.0
TH1_k127_3252049_1 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 422.0
TH1_k127_3252049_2 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000004499 229.0
TH1_k127_3252049_3 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000195 180.0
TH1_k127_3252049_4 PAP2 superfamily - - - 0.0000000000000000004788 102.0
TH1_k127_3252049_5 peptidase inhibitor activity - - - 0.000000000000001639 87.0
TH1_k127_3329817_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 568.0
TH1_k127_3329817_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 529.0
TH1_k127_3329817_10 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000007516 145.0
TH1_k127_3329817_11 TIGRFAM TonB family protein K03832 - - 0.0000002899 57.0
TH1_k127_3329817_13 RDD family - - - 0.00003701 54.0
TH1_k127_3329817_2 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 314.0
TH1_k127_3329817_3 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001771 272.0
TH1_k127_3329817_4 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000009042 265.0
TH1_k127_3329817_5 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000003573 219.0
TH1_k127_3329817_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000001523 213.0
TH1_k127_3329817_7 Psort location Cytoplasmic, score 8.96 K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000005273 187.0
TH1_k127_3329817_8 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000006046 198.0
TH1_k127_3329817_9 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000004182 148.0
TH1_k127_3354168_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.744e-241 786.0
TH1_k127_3354168_1 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000001019 216.0
TH1_k127_3354168_2 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000001376 132.0
TH1_k127_3354168_3 COG0760 Parvulin-like peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.00000000000004451 86.0
TH1_k127_3372066_0 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000953 291.0
TH1_k127_3372066_1 PFAM PKD domain containing protein - - - 0.000000000000000000008747 110.0
TH1_k127_3372066_2 Glycosyl transferase family 2 K16870 - 2.4.1.289 0.0000000000000000002854 100.0
TH1_k127_3372066_3 Glycosyl transferases group 1 - - - 0.0000000000000258 87.0
TH1_k127_3372066_4 transferase activity, transferring acyl groups K03824 - - 0.0002118 53.0
TH1_k127_3401955_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000001383 222.0
TH1_k127_3403338_0 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009435 427.0
TH1_k127_3403338_1 periplasmic solute binding protein K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 394.0
TH1_k127_3403338_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 293.0
TH1_k127_3403338_3 pfam abc-3 K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 295.0
TH1_k127_3403338_4 lipoprotein localization to outer membrane K02004,K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002367 284.0
TH1_k127_3403338_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000006359 237.0
TH1_k127_3403338_6 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000748 198.0
TH1_k127_3403338_7 ABC 3 transport family K09816 GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000001385 99.0
TH1_k127_3410396_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.418e-222 719.0
TH1_k127_3410396_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 439.0
TH1_k127_3410396_2 Gamma-glutamyl-gamma-aminobutyrate hydrolase K07010 - - 0.000000000000000000000000000000000000000000000000000000000000001146 227.0
TH1_k127_3410396_3 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000288 213.0
TH1_k127_3410396_4 phenazine biosynthesis protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000007979 192.0
TH1_k127_3410396_5 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000001119 194.0
TH1_k127_3410396_6 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000002137 103.0
TH1_k127_3437229_0 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 344.0
TH1_k127_3437229_1 arylsulfatase A K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 316.0
TH1_k127_3437229_10 SBF-like CPA transporter family (DUF4137) K03453 - - 0.000000000000000000000000007442 126.0
TH1_k127_3437229_11 Protein of unknown function (DUF2490) - - - 0.000000000000000000000000009871 120.0
TH1_k127_3437229_12 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000001446 100.0
TH1_k127_3437229_14 - - - - 0.000000000005207 74.0
TH1_k127_3437229_15 - - - - 0.000000001436 68.0
TH1_k127_3437229_2 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 325.0
TH1_k127_3437229_3 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 313.0
TH1_k127_3437229_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 302.0
TH1_k127_3437229_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000011 166.0
TH1_k127_3437229_6 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000002607 155.0
TH1_k127_3437229_7 Protein of unknown function - - - 0.00000000000000000000000000000004012 147.0
TH1_k127_3437229_8 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000000000004271 129.0
TH1_k127_3437229_9 - - - - 0.0000000000000000000000000001316 123.0
TH1_k127_34824_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 472.0
TH1_k127_34824_1 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 379.0
TH1_k127_34824_10 Regulatory protein MerR - - - 0.00000000000000001913 89.0
TH1_k127_34824_11 Major facilitator Superfamily - - - 0.0000002377 54.0
TH1_k127_34824_12 cheY-homologous receiver domain K03413 - - 0.000001003 61.0
TH1_k127_34824_13 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0001408 50.0
TH1_k127_34824_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 346.0
TH1_k127_34824_3 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000111 224.0
TH1_k127_34824_4 Domain of unknown function (DUF3473) - - - 0.000000000000000000000000000000000000000000000006699 185.0
TH1_k127_34824_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000004546 159.0
TH1_k127_34824_6 protein involved in formate dehydrogenase formation K02380 - - 0.0000000000000000000000000000005194 135.0
TH1_k127_34824_7 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000006341 123.0
TH1_k127_34824_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000001394 99.0
TH1_k127_34824_9 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000001188 100.0
TH1_k127_3491_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 2.938e-294 925.0
TH1_k127_3491_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.263e-259 825.0
TH1_k127_3491_10 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 294.0
TH1_k127_3491_11 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000004226 244.0
TH1_k127_3491_12 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000006727 216.0
TH1_k127_3491_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000001625 192.0
TH1_k127_3491_14 - K07071 - - 0.000000000000000000000000000000000000000000000002018 185.0
TH1_k127_3491_15 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000000000000001247 160.0
TH1_k127_3491_16 Membrane - - - 0.000000000000002529 91.0
TH1_k127_3491_17 protein-disulfide reductase activity K01829,K04084 - 1.8.1.8,5.3.4.1 0.000000000000385 76.0
TH1_k127_3491_18 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.0000000003503 66.0
TH1_k127_3491_2 Polysulphide reductase, NrfD K00185 - - 1.901e-203 664.0
TH1_k127_3491_21 - - - - 0.0001073 46.0
TH1_k127_3491_3 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 2.366e-194 623.0
TH1_k127_3491_4 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 510.0
TH1_k127_3491_5 Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 432.0
TH1_k127_3491_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 360.0
TH1_k127_3491_7 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 310.0
TH1_k127_3491_8 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 318.0
TH1_k127_3491_9 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 310.0
TH1_k127_3511914_0 FHA domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 334.0
TH1_k127_3551265_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 475.0
TH1_k127_3551265_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 360.0
TH1_k127_3551265_2 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 321.0
TH1_k127_3551265_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 317.0
TH1_k127_3551265_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001029 280.0
TH1_k127_3551265_5 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000001083 240.0
TH1_k127_3551265_6 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000335 225.0
TH1_k127_3551265_7 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000004847 175.0
TH1_k127_3551265_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000001964 126.0
TH1_k127_3551265_9 Yip1 domain - - - 0.0000000001984 71.0
TH1_k127_3555136_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.285e-255 799.0
TH1_k127_3555136_1 belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 517.0
TH1_k127_3555136_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 462.0
TH1_k127_3555136_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000008403 186.0
TH1_k127_3555136_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000002869 108.0
TH1_k127_3555136_5 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.000000000000000004497 89.0
TH1_k127_3555136_6 PAP2 superfamily - - - 0.00000000000000002351 97.0
TH1_k127_3555136_7 COG0671 Membrane-associated phospholipid phosphatase - - - 0.000000000000003497 89.0
TH1_k127_3555136_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000004959 69.0
TH1_k127_3579415_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 404.0
TH1_k127_3579415_1 peptidase U62, modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000001384 152.0
TH1_k127_3665298_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1217.0
TH1_k127_3665298_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 549.0
TH1_k127_3665298_10 Peptidase family M23 K21472 - - 0.0000000000000000000000002898 119.0
TH1_k127_3665298_11 GAF domain - - - 0.00000000005585 76.0
TH1_k127_3665298_12 Cyclic nucleotide-monophosphate binding domain - - - 0.000000004811 67.0
TH1_k127_3665298_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 409.0
TH1_k127_3665298_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 403.0
TH1_k127_3665298_4 Dihydroxyacetone kinase family K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 389.0
TH1_k127_3665298_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000871 226.0
TH1_k127_3665298_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000026 162.0
TH1_k127_3665298_7 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000000001388 174.0
TH1_k127_3665298_8 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000001453 137.0
TH1_k127_3665298_9 lipase activity K15349 - - 0.00000000000000000000000000001121 136.0
TH1_k127_3669290_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001459 239.0
TH1_k127_3669290_2 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.00000000000000000000000000000000000002613 151.0
TH1_k127_3669290_3 transferase activity, transferring glycosyl groups K20534 - - 0.00000000000000000000000001006 115.0
TH1_k127_3669959_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 579.0
TH1_k127_3669959_1 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 508.0
TH1_k127_3669959_10 aminotransferase K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000009801 215.0
TH1_k127_3669959_11 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000003221 179.0
TH1_k127_3669959_12 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000000000000000000000000006871 169.0
TH1_k127_3669959_13 KR domain K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000004101 167.0
TH1_k127_3669959_14 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000002268 168.0
TH1_k127_3669959_15 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000002841 163.0
TH1_k127_3669959_16 Bacterial regulatory proteins, tetR family K13770 - - 0.00000000000000000000000000000000000003495 153.0
TH1_k127_3669959_17 nitric oxide dioxygenase activity - - - 0.00000000000000000000000526 114.0
TH1_k127_3669959_18 Domain of unknown function (DUF4833) - - - 0.000000000000002082 83.0
TH1_k127_3669959_19 Domain of unknown function (DUF4136) - - - 0.000005733 56.0
TH1_k127_3669959_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 498.0
TH1_k127_3669959_3 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 436.0
TH1_k127_3669959_4 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 438.0
TH1_k127_3669959_5 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 437.0
TH1_k127_3669959_6 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 425.0
TH1_k127_3669959_7 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001886 286.0
TH1_k127_3669959_8 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004348 287.0
TH1_k127_3669959_9 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000005263 275.0
TH1_k127_3767014_0 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 488.0
TH1_k127_3767014_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 353.0
TH1_k127_3767014_2 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 348.0
TH1_k127_3767014_3 KH domain K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008748 279.0
TH1_k127_3767014_4 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000001734 231.0
TH1_k127_3767014_5 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000003824 218.0
TH1_k127_3767014_6 of the beta-lactamase K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000003654 177.0
TH1_k127_3767014_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000004911 102.0
TH1_k127_3767014_8 Glycosyltransferase family 92 - - - 0.00000000000000000001284 104.0
TH1_k127_3776234_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 535.0
TH1_k127_3776234_1 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000009266 61.0
TH1_k127_3778869_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000412 230.0
TH1_k127_3778869_1 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.0000000000000000000000000000000000000892 149.0
TH1_k127_3778869_2 Nitrile hydratase - - - 0.00003038 51.0
TH1_k127_3778869_3 Nitrile hydratase - - - 0.00008467 50.0
TH1_k127_378162_0 mRNA catabolic process K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 517.0
TH1_k127_378162_2 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 295.0
TH1_k127_378162_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000002817 175.0
TH1_k127_378162_5 -O-antigen - - - 0.0000000001241 73.0
TH1_k127_378162_6 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000002 64.0
TH1_k127_378162_7 Protein of unknown function, DUF481 K07283 - - 0.000000002784 68.0
TH1_k127_378162_8 Belongs to the UPF0434 family K09791 - - 0.00004138 55.0
TH1_k127_3796197_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003027 299.0
TH1_k127_3796197_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000002832 223.0
TH1_k127_3802313_0 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 503.0
TH1_k127_3802313_1 - - - - 0.00000000000000000000000000000000000000000000000002024 188.0
TH1_k127_3802313_2 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000002474 199.0
TH1_k127_3802313_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000005838 135.0
TH1_k127_3808694_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 487.0
TH1_k127_3808694_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 466.0
TH1_k127_3808694_10 YacP-like NYN domain - - - 0.000003731 55.0
TH1_k127_3808694_11 Domain of unknown function (DUF4388) - - - 0.0004167 53.0
TH1_k127_3808694_2 Pro-kumamolisin, activation domain K08677 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 406.0
TH1_k127_3808694_3 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 396.0
TH1_k127_3808694_4 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000002791 207.0
TH1_k127_3808694_5 Peptidase family M50 K06402 - - 0.000000000000000000000000000000000000000000000873 173.0
TH1_k127_3808694_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000014 170.0
TH1_k127_3808694_7 histone H2A K63-linked ubiquitination K10914 - - 0.00000000000000000000000000000000000004472 155.0
TH1_k127_3808694_8 Domain of unknown function (DUF4126) - - - 0.00000000000000000001545 104.0
TH1_k127_3808694_9 - - - - 0.000000000002878 80.0
TH1_k127_3839490_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.673e-236 742.0
TH1_k127_3839490_1 O-acetylhomoserine K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 507.0
TH1_k127_3839490_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000002261 143.0
TH1_k127_3839490_11 regulation of translation K03530 - - 0.000000000000000000000000000000001497 133.0
TH1_k127_3839490_12 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000001193 83.0
TH1_k127_3839490_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 433.0
TH1_k127_3839490_3 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 301.0
TH1_k127_3839490_4 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001337 280.0
TH1_k127_3839490_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005159 283.0
TH1_k127_3839490_6 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002376 236.0
TH1_k127_3839490_7 Major facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000002793 206.0
TH1_k127_3839490_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000003378 212.0
TH1_k127_3839490_9 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.00000000000000000000000000000000000000000002796 185.0
TH1_k127_3884743_0 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 460.0
TH1_k127_3884743_1 Aldehyde dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 462.0
TH1_k127_3884743_10 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000009429 208.0
TH1_k127_3884743_11 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000003953 204.0
TH1_k127_3884743_12 glycosyl transferase family 2 K12984 - - 0.0000000000000000000000000000000000000000007162 170.0
TH1_k127_3884743_13 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000005716 127.0
TH1_k127_3884743_14 Tyrosine phosphatase family - - - 0.00000000000000000003761 102.0
TH1_k127_3884743_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000005733 76.0
TH1_k127_3884743_16 OsmC-like protein - - - 0.00005089 56.0
TH1_k127_3884743_17 Nucleotidyl transferase - - - 0.00008129 55.0
TH1_k127_3884743_2 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 436.0
TH1_k127_3884743_3 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 452.0
TH1_k127_3884743_4 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 351.0
TH1_k127_3884743_5 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 338.0
TH1_k127_3884743_6 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001197 271.0
TH1_k127_3884743_8 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000005061 228.0
TH1_k127_3884743_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000001125 213.0
TH1_k127_3889663_0 Alpha amylase, catalytic domain - - - 7.459e-225 709.0
TH1_k127_3889663_1 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007907 265.0
TH1_k127_3889663_2 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000001795 133.0
TH1_k127_3896703_0 GatB domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 463.0
TH1_k127_3896703_1 Belongs to the HpcH HpaI aldolase family K01644,K14451,K18292 - 3.1.2.30,4.1.3.25,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 290.0
TH1_k127_3896703_2 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006276 247.0
TH1_k127_3896703_3 Polysaccharide biosynthesis protein K08678 - 4.1.1.35 0.0000000000000000000000000000000005326 145.0
TH1_k127_3896703_4 AI-2E family transporter - - - 0.0000000000000000000000000000001223 139.0
TH1_k127_3896703_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000004022 95.0
TH1_k127_3896703_6 transferase activity, transferring glycosyl groups K20534 - - 0.0000000000001212 80.0
TH1_k127_3896703_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000007515 61.0
TH1_k127_3897056_0 Crp-like helix-turn-helix domain K10914 - - 0.00000000000000000000000000000001731 135.0
TH1_k127_3897056_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000003597 127.0
TH1_k127_3904221_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 446.0
TH1_k127_3904221_1 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 361.0
TH1_k127_3904221_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000003355 256.0
TH1_k127_3904221_3 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000002818 176.0
TH1_k127_3904221_4 - - - - 0.0000000000000000001385 93.0
TH1_k127_3912437_0 PFAM DAHP synthetase I KDSA K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 464.0
TH1_k127_3912437_1 TIGRFAM amidohydrolase K12941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 372.0
TH1_k127_3912437_10 cell septum assembly - - - 0.0000000000000000000000000004247 126.0
TH1_k127_3912437_11 Protein of unknown function, DUF547 - - - 0.000000000000000007753 94.0
TH1_k127_3912437_12 - - - - 0.0000000000000005634 89.0
TH1_k127_3912437_13 Tetratricopeptide repeat - - - 0.00021 52.0
TH1_k127_3912437_2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 332.0
TH1_k127_3912437_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 336.0
TH1_k127_3912437_4 synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003375 279.0
TH1_k127_3912437_5 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000001033 221.0
TH1_k127_3912437_6 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000007888 187.0
TH1_k127_3912437_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000002535 184.0
TH1_k127_3912437_8 von Willebrand factor, type A - - - 0.000000000000000000000000000000000002892 158.0
TH1_k127_3912437_9 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000001058 140.0
TH1_k127_3944471_0 radical SAM domain protein K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 541.0
TH1_k127_3944471_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 526.0
TH1_k127_3944471_2 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000003591 196.0
TH1_k127_3944471_3 SdrD B-like domain - - - 0.0000000000000000000000000734 127.0
TH1_k127_3944471_4 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.0000000000000009194 83.0
TH1_k127_3944471_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00009634 57.0
TH1_k127_3961679_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 419.0
TH1_k127_3961679_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 390.0
TH1_k127_3961679_10 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000008807 127.0
TH1_k127_3961679_11 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.000000000000000000000074 102.0
TH1_k127_3961679_12 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.00000000000000000000133 100.0
TH1_k127_3961679_13 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000007397 77.0
TH1_k127_3961679_14 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0001147 56.0
TH1_k127_3961679_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 352.0
TH1_k127_3961679_3 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 334.0
TH1_k127_3961679_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 296.0
TH1_k127_3961679_5 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002036 285.0
TH1_k127_3961679_6 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002059 299.0
TH1_k127_3961679_7 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000006464 251.0
TH1_k127_3961679_8 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000001839 192.0
TH1_k127_3961679_9 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000005928 182.0
TH1_k127_3968953_0 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 3.977e-238 757.0
TH1_k127_3968953_1 Prolyl oligopeptidase family - - - 1.318e-197 638.0
TH1_k127_3968953_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005559 236.0
TH1_k127_3968953_11 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000002311 183.0
TH1_k127_3968953_12 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000001021 154.0
TH1_k127_3968953_13 Responsible for synthesis of pseudouridine from uracil K06179,K06180 - 5.4.99.23,5.4.99.24 0.0000000000000000000000002522 120.0
TH1_k127_3968953_14 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000003445 117.0
TH1_k127_3968953_15 Yip1 domain - - - 0.0000000000000000000000005535 117.0
TH1_k127_3968953_16 Protein of unknown function (DUF2089) - - - 0.00000000000000000006258 92.0
TH1_k127_3968953_17 - - - - 0.0000000000002702 82.0
TH1_k127_3968953_18 - - - - 0.000000000004648 76.0
TH1_k127_3968953_2 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 505.0
TH1_k127_3968953_20 Protein of unknown function (DUF2752) - - - 0.00000003758 65.0
TH1_k127_3968953_21 - - - - 0.0000005188 54.0
TH1_k127_3968953_22 - - - - 0.0001427 48.0
TH1_k127_3968953_23 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.000207 54.0
TH1_k127_3968953_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 473.0
TH1_k127_3968953_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 424.0
TH1_k127_3968953_5 unsaturated fatty acid biosynthetic process K04712 - 1.14.18.5,1.14.19.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 404.0
TH1_k127_3968953_6 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 413.0
TH1_k127_3968953_7 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 403.0
TH1_k127_3968953_8 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 408.0
TH1_k127_3968953_9 molybdenum ion binding K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000005017 241.0
TH1_k127_3988234_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.863e-304 949.0
TH1_k127_3988234_1 Elongation factor Tu C-terminal domain K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 608.0
TH1_k127_3988234_10 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000002095 169.0
TH1_k127_3988234_11 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000007492 161.0
TH1_k127_3988234_12 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000009202 152.0
TH1_k127_3988234_13 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000361 89.0
TH1_k127_3988234_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 604.0
TH1_k127_3988234_3 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 534.0
TH1_k127_3988234_4 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 406.0
TH1_k127_3988234_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 387.0
TH1_k127_3988234_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002431 244.0
TH1_k127_3988234_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000003164 241.0
TH1_k127_3988234_8 Squalene/phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000006411 255.0
TH1_k127_3988234_9 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000004633 223.0
TH1_k127_3997083_0 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 357.0
TH1_k127_3997083_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000004081 273.0
TH1_k127_3997083_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000005366 173.0
TH1_k127_3997083_3 Putative ATP-binding cassette K01992 - - 0.000004792 57.0
TH1_k127_4002473_0 Prolyl oligopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 542.0
TH1_k127_4002473_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 477.0
TH1_k127_4002473_2 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000008192 222.0
TH1_k127_4002473_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K00558,K07457,K10773 - 2.1.1.37,4.2.99.18 0.000000000000000000000000000000000000000003579 166.0
TH1_k127_4002473_4 Outer membrane lipoprotein-sorting protein - - - 0.0000009485 55.0
TH1_k127_4046897_0 Insecticidal toxin complex protein TcaC - - - 0.00000000000622 79.0
TH1_k127_4086778_0 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 341.0
TH1_k127_4086778_1 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000006704 170.0
TH1_k127_4086778_2 protein conserved in bacteria K09778 - - 0.00000000000000000000000000009969 124.0
TH1_k127_4086778_3 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000000000213 128.0
TH1_k127_4107177_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 316.0
TH1_k127_4107177_1 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000007166 239.0
TH1_k127_4107177_2 DinB family - - - 0.00000000000000000000000000000000000000003898 168.0
TH1_k127_4107177_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000007569 169.0
TH1_k127_4107177_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000008396 147.0
TH1_k127_4107177_5 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000004475 110.0
TH1_k127_4107177_6 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000001662 70.0
TH1_k127_4122351_0 PFAM Peptidase M20 - - - 0.00000000000000000000000000000000003472 155.0
TH1_k127_4122351_2 Bacterial membrane protein, YfhO - - - 0.0002163 53.0
TH1_k127_412646_0 Transport of potassium into the cell K03549 - - 7.989e-197 653.0
TH1_k127_412646_1 AMP-binding enzyme K01897 - 6.2.1.3 6.002e-195 623.0
TH1_k127_412646_10 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000001725 211.0
TH1_k127_412646_11 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000002937 142.0
TH1_k127_412646_12 Cytidylate kinase-like family - - - 0.000000000000000000000000007846 119.0
TH1_k127_412646_13 Response regulator receiver domain - - - 0.0000000000007772 81.0
TH1_k127_412646_2 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 512.0
TH1_k127_412646_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 437.0
TH1_k127_412646_4 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 388.0
TH1_k127_412646_5 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 356.0
TH1_k127_412646_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 338.0
TH1_k127_412646_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 323.0
TH1_k127_412646_8 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0031403,GO:0031420,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0047954,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000005182 243.0
TH1_k127_412646_9 Belongs to the peptidase M24B family K01271,K01274 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000001346 239.0
TH1_k127_4198379_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 1.464e-223 724.0
TH1_k127_4198379_1 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 583.0
TH1_k127_4198379_10 synthase - - - 0.0003289 53.0
TH1_k127_4198379_2 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 442.0
TH1_k127_4198379_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 331.0
TH1_k127_4198379_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 304.0
TH1_k127_4198379_5 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001592 275.0
TH1_k127_4198379_6 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004269 285.0
TH1_k127_4198379_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000118 237.0
TH1_k127_4198379_8 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000001107 240.0
TH1_k127_4198379_9 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000008643 60.0
TH1_k127_4249604_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 526.0
TH1_k127_4249604_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 508.0
TH1_k127_434293_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003143 293.0
TH1_k127_434293_1 PFAM Peptidase M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002262 278.0
TH1_k127_434293_2 PFAM Peptidase M16 - - - 0.000000000000000000000000000000000000001599 168.0
TH1_k127_435222_0 FAD linked oxidase domain protein - - - 0.0 1437.0
TH1_k127_435222_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 5e-324 1032.0
TH1_k127_435222_2 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009314,GO:0009628,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019676,GO:0019740,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.2 7.621e-242 757.0
TH1_k127_435222_3 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 291.0
TH1_k127_435222_4 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000006627 206.0
TH1_k127_435222_5 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000001328 172.0
TH1_k127_435222_6 DinB family - - - 0.000000000000000000000000000000000000002228 152.0
TH1_k127_435222_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000003213 163.0
TH1_k127_435222_8 - - - - 0.000000000000006922 82.0
TH1_k127_443729_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 426.0
TH1_k127_443729_1 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000001723 161.0
TH1_k127_443729_2 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000001189 157.0
TH1_k127_443729_3 TonB C terminal K03832 - - 0.000000000000000000000000002352 117.0
TH1_k127_443729_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000008519 74.0
TH1_k127_443729_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.00000000007124 66.0
TH1_k127_443729_6 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.000001919 51.0
TH1_k127_443729_7 Aminotransferase class-V K04487 - 2.8.1.7 0.00004667 52.0
TH1_k127_446386_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 544.0
TH1_k127_446386_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 453.0
TH1_k127_446386_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000118 132.0
TH1_k127_446386_3 site-specific recombinase - - - 0.00001001 53.0
TH1_k127_4541274_0 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 7.697e-257 806.0
TH1_k127_4541274_1 response regulator - - - 3.674e-202 638.0
TH1_k127_4541274_10 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 383.0
TH1_k127_4541274_11 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 335.0
TH1_k127_4541274_12 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000616 203.0
TH1_k127_4541274_13 Glycine cleavage H-protein - - - 0.000000000000000000000000000000000000000000000001647 185.0
TH1_k127_4541274_14 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000000000000004271 179.0
TH1_k127_4541274_15 TIGRFAM SUF system FeS K04488 - - 0.00000000000000000000000000000000000000000000006693 190.0
TH1_k127_4541274_16 Transcriptional regulator - - - 0.0000000000000000000000000000000000001542 147.0
TH1_k127_4541274_17 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.0000000000000000000000000000002197 134.0
TH1_k127_4541274_18 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000007241 142.0
TH1_k127_4541274_2 Insulinase (Peptidase family M16) K07263 - - 6.351e-198 625.0
TH1_k127_4541274_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 571.0
TH1_k127_4541274_4 HAMP domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 490.0
TH1_k127_4541274_5 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 443.0
TH1_k127_4541274_6 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 409.0
TH1_k127_4541274_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 384.0
TH1_k127_4541274_8 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 376.0
TH1_k127_4541274_9 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 366.0
TH1_k127_4621673_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1141.0
TH1_k127_4621673_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 348.0
TH1_k127_4621673_10 - - - - 0.00000000000000000007318 94.0
TH1_k127_4621673_11 Glycosyl transferase family 2 K07011 - - 0.0000000000000006731 92.0
TH1_k127_4621673_12 C-terminal domain of CHU protein family - - - 0.000002353 61.0
TH1_k127_4621673_13 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.00000615 57.0
TH1_k127_4621673_15 Immunoglobulin I-set domain protein K01179,K01406 - 3.2.1.4,3.4.24.40 0.00006806 55.0
TH1_k127_4621673_2 ABC transporter related K01990,K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000002242 239.0
TH1_k127_4621673_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000004405 236.0
TH1_k127_4621673_4 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000004779 231.0
TH1_k127_4621673_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000009728 178.0
TH1_k127_4621673_6 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000004599 178.0
TH1_k127_4621673_7 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000002064 163.0
TH1_k127_4621673_8 HD domain - - - 0.0000000000000000000000000000000000000002115 170.0
TH1_k127_4621673_9 gluconolactonase activity - - - 0.000000000000000000000000000000000000001681 169.0
TH1_k127_4625059_0 Sortilin, neurotensin receptor 3, - - - 0.0 1230.0
TH1_k127_4625059_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 6.464e-220 734.0
TH1_k127_4625059_10 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 299.0
TH1_k127_4625059_11 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 306.0
TH1_k127_4625059_12 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009079 278.0
TH1_k127_4625059_13 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000006116 179.0
TH1_k127_4625059_14 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.000000000000000000000000000000009622 143.0
TH1_k127_4625059_15 Protein of unknown function (DUF1579) - - - 0.0000004425 61.0
TH1_k127_4625059_16 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00007814 47.0
TH1_k127_4625059_2 Involved in the tonB-independent uptake of proteins - - - 2.528e-217 706.0
TH1_k127_4625059_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 9.669e-212 688.0
TH1_k127_4625059_4 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 1.421e-201 641.0
TH1_k127_4625059_5 Involved in the tonB-independent uptake of proteins - - - 2.162e-194 639.0
TH1_k127_4625059_6 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 594.0
TH1_k127_4625059_7 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 548.0
TH1_k127_4625059_8 PFAM Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 376.0
TH1_k127_4625059_9 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 383.0
TH1_k127_4658925_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 8.322e-211 677.0
TH1_k127_4658925_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 580.0
TH1_k127_4658925_10 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000008313 79.0
TH1_k127_4658925_2 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 415.0
TH1_k127_4658925_3 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 392.0
TH1_k127_4658925_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 351.0
TH1_k127_4658925_5 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000008381 216.0
TH1_k127_4658925_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000001181 181.0
TH1_k127_4658925_7 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000000000000000000000004201 178.0
TH1_k127_4658925_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000002969 146.0
TH1_k127_4658925_9 Translation elongation factor P EF-P - - - 0.00000000000000000000000000000000000958 139.0
TH1_k127_4722056_0 Multicopper K06324 - 1.16.3.3 1.156e-297 955.0
TH1_k127_4722056_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.14e-201 637.0
TH1_k127_4722056_2 AAA ATPase, central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 487.0
TH1_k127_4722056_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000009562 207.0
TH1_k127_4722056_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000006855 182.0
TH1_k127_4722056_5 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000006851 154.0
TH1_k127_4722056_6 Tetratricopeptide repeat - - - 0.000000000000000005805 96.0
TH1_k127_4722056_7 phosphatidylinositol metabolic process K00728 - 2.4.1.109 0.00005942 55.0
TH1_k127_4737582_0 PFAM GlcNAc-PI de-N-acetylase - - - 2.07e-237 760.0
TH1_k127_4737582_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000001351 179.0
TH1_k127_4737582_2 CAAX protease self-immunity K07052 - - 0.0000000000001302 81.0
TH1_k127_4811357_0 3-demethylubiquinone-9 3-O-methyltransferase activity K07011,K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 372.0
TH1_k127_4811357_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000005686 53.0
TH1_k127_4870203_0 Two component regulator propeller K07315,K12132,K13924 - 2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3 3.303e-243 788.0
TH1_k127_4870203_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 596.0
TH1_k127_4870203_10 NMT1-like family K02051 - - 0.000000000000000000000002216 117.0
TH1_k127_4870203_11 4Fe-4S dicluster domain - - - 0.0000000000000000000001198 99.0
TH1_k127_4870203_12 B12 binding domain - - - 0.00000000000000000004909 100.0
TH1_k127_4870203_2 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 603.0
TH1_k127_4870203_3 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 390.0
TH1_k127_4870203_4 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 355.0
TH1_k127_4870203_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 295.0
TH1_k127_4870203_6 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002831 259.0
TH1_k127_4870203_7 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000002012 216.0
TH1_k127_4870203_8 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000004189 134.0
TH1_k127_4870203_9 NMT1-like family K02051 - - 0.0000000000000000000000001452 118.0
TH1_k127_4919595_0 PFAM Protein synthesis factor, GTP-binding K06207 - - 1.25e-247 778.0
TH1_k127_4919595_1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 359.0
TH1_k127_4919595_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 293.0
TH1_k127_4919595_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000002429 160.0
TH1_k127_4919595_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000006646 132.0
TH1_k127_4919595_5 CpeT/CpcT family (DUF1001) - - - 0.0000000000000000000003926 104.0
TH1_k127_4919595_6 Rhomboid family - - - 0.0000000000000000004739 101.0
TH1_k127_4919595_7 Bacterial Ig-like domain (group 3) - - - 0.0000000000000008673 93.0
TH1_k127_4919595_8 - - - - 0.00002338 53.0
TH1_k127_4919595_9 - - - - 0.0002397 52.0
TH1_k127_4925599_0 Sortilin, neurotensin receptor 3, - - - 5e-323 1048.0
TH1_k127_4925599_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 526.0
TH1_k127_4925599_2 major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000001726 195.0
TH1_k127_494998_0 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 541.0
TH1_k127_494998_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000007719 179.0
TH1_k127_494998_2 aminoacyl-tRNA hydrolase activity K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000002108 183.0
TH1_k127_494998_3 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000002662 139.0
TH1_k127_494998_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000001014 103.0
TH1_k127_494998_5 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000003516 76.0
TH1_k127_4994825_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 427.0
TH1_k127_4994825_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 382.0
TH1_k127_4994825_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000005706 267.0
TH1_k127_4994825_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000002811 224.0
TH1_k127_4994825_4 SMART phosphoesterase PA-phosphatase related - - - 0.00000000000000000000000000000000000000000003074 171.0
TH1_k127_4994825_5 Aspartyl protease - - - 0.00001196 59.0
TH1_k127_5006984_0 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000006599 177.0
TH1_k127_5006984_1 ECF sigma factor K03088 - - 0.00000000000000000000000001069 118.0
TH1_k127_5006984_2 Heavy-metal resistance - - - 0.000000000000000007676 95.0
TH1_k127_5006984_3 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000001488 88.0
TH1_k127_5006984_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000001581 64.0
TH1_k127_5028594_0 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 427.0
TH1_k127_5028594_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000002466 187.0
TH1_k127_504390_0 Peptide transporter - - - 6.972e-221 707.0
TH1_k127_504390_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 585.0
TH1_k127_504390_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 540.0
TH1_k127_504390_3 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 429.0
TH1_k127_504390_4 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004102 283.0
TH1_k127_504390_5 homoserine transmembrane transporter activity K06600,K06895 - - 0.00000000000000000000000000000003751 135.0
TH1_k127_504390_6 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000001757 96.0
TH1_k127_504390_7 FAD dependent oxidoreductase - - - 0.00000000000000000001385 107.0
TH1_k127_5046368_0 COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 509.0
TH1_k127_5046368_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 403.0
TH1_k127_5046368_2 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 406.0
TH1_k127_5046368_3 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 301.0
TH1_k127_5046368_4 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004048 239.0
TH1_k127_5046368_5 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000005723 227.0
TH1_k127_5046368_6 diguanylate cyclase - - - 0.000000000000000000000000000000000000001196 166.0
TH1_k127_5046368_7 metallopeptidase activity - - - 0.00005627 51.0
TH1_k127_5114970_0 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 504.0
TH1_k127_5114970_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 474.0
TH1_k127_5114970_10 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000003243 90.0
TH1_k127_5114970_11 radical SAM domain protein - - - 0.0000001054 55.0
TH1_k127_5114970_2 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000000000000001071 195.0
TH1_k127_5114970_3 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000002074 181.0
TH1_k127_5114970_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000009455 164.0
TH1_k127_5114970_5 Peptidase C26 K07010 - - 0.000000000000000000000000000000000007137 154.0
TH1_k127_5114970_6 methylamine metabolic process - - - 0.0000000000000000000000000000000002314 143.0
TH1_k127_5114970_7 Belongs to the Fur family K09825 - - 0.00000000000000000000000000000002894 130.0
TH1_k127_5114970_8 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.000000000000000000000000000002455 128.0
TH1_k127_5114970_9 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.00000000000000000000000000000326 130.0
TH1_k127_5129920_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000007765 239.0
TH1_k127_5129920_1 protein kinase activity - - - 0.000000008733 66.0
TH1_k127_5131254_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 542.0
TH1_k127_5131254_1 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000684 208.0
TH1_k127_5131254_2 Putative 2OG-Fe(II) oxygenase - - - 0.00002089 57.0
TH1_k127_5131859_0 ThiF family K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 335.0
TH1_k127_5131859_1 Glycosyl hydrolase family 36 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 331.0
TH1_k127_5131859_2 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 319.0
TH1_k127_5131859_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 321.0
TH1_k127_5131859_4 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000002343 121.0
TH1_k127_5131859_5 Forkhead associated domain K03466 - - 0.0000005486 57.0
TH1_k127_5191004_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 412.0
TH1_k127_5191004_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 357.0
TH1_k127_5191004_2 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 287.0
TH1_k127_5191004_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000000000000000000000000000000000003871 199.0
TH1_k127_5191004_4 Phosphoesterase, PA-phosphatase related protein - - - 0.000000000000000000000000007727 123.0
TH1_k127_5191004_5 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000000000000000001139 113.0
TH1_k127_5191004_6 protein homooligomerization - - - 0.00000000000000000000000003021 124.0
TH1_k127_5191004_7 to the N-terminal domain of Lon protease K07157 - - 0.00000000000000000000000006503 123.0
TH1_k127_5191004_8 PFAM Pentapeptide repeats (8 copies) - - - 0.000000000002558 79.0
TH1_k127_5191004_9 TIGRFAM cytochrome c oxidase, cbb3-type, subunit III K00406 - - 0.0000000696 59.0
TH1_k127_5224088_0 Belongs to the ClpA ClpB family K03696 - - 1.387e-281 897.0
TH1_k127_5224088_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 537.0
TH1_k127_5224088_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778 - 0.0000000000000000000000000000000000000000000000000000003453 206.0
TH1_k127_5224088_3 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000003116 77.0
TH1_k127_5247006_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 563.0
TH1_k127_5247006_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000001459 227.0
TH1_k127_5247006_2 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000000000000000000004871 139.0
TH1_k127_5247006_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000006751 128.0
TH1_k127_5299136_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 1.878e-248 784.0
TH1_k127_5299136_1 carboxylase K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 486.0
TH1_k127_5299136_2 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 341.0
TH1_k127_5299136_3 enoyl-CoA hydratase K13766,K13779 - 4.2.1.18,4.2.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000001215 251.0
TH1_k127_5299136_4 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000002136 181.0
TH1_k127_5299136_5 response regulator - - - 0.0000000000000000000000000000001428 126.0
TH1_k127_5299136_6 acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 0.000000000000007721 82.0
TH1_k127_5299136_7 type II secretion system protein K02243,K02652 - - 0.00000000008856 70.0
TH1_k127_5327627_0 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000003636 156.0
TH1_k127_5327627_1 BatD protein - - - 0.000000000000000007547 99.0
TH1_k127_5383467_0 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 416.0
TH1_k127_5383467_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 359.0
TH1_k127_5383467_2 PFAM von Willebrand factor type A - - - 0.0000000000000000000004148 111.0
TH1_k127_5405460_0 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 347.0
TH1_k127_5405460_1 Twitching motility protein PilT K02669 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 351.0
TH1_k127_5405460_2 Histidine kinase K02668,K07708 - 2.7.13.3 0.000000000000000000000000000008086 136.0
TH1_k127_5405460_3 Neisseria PilC beta-propeller domain K02674 - - 0.00000000000000000002057 109.0
TH1_k127_5408483_0 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005708 251.0
TH1_k127_5408483_1 cellulose binding - - - 0.00000000000000000399 95.0
TH1_k127_5408483_2 Bacterial membrane protein YfhO - - - 0.00000003217 67.0
TH1_k127_5416505_0 Alcohol dehydrogenase GroES-like domain K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 523.0
TH1_k127_5416505_1 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 325.0
TH1_k127_5416505_10 glyoxalase III activity - - - 0.000000000000000000000000000000000000003003 157.0
TH1_k127_5416505_11 YhhN family - - - 0.00000000000000000000000000000000000008042 152.0
TH1_k127_5416505_12 - - - - 0.0000000000000000000000000000000000006809 151.0
TH1_k127_5416505_13 CoA binding domain K06929 - - 0.00000000000000000000000000000001035 138.0
TH1_k127_5416505_14 Phospholipid methyltransferase - - - 0.0000000000000000000000000000003005 129.0
TH1_k127_5416505_15 Putative lumazine-binding - - - 0.000000000000000000000001497 115.0
TH1_k127_5416505_17 - - - - 0.000000000000000002123 91.0
TH1_k127_5416505_18 Ankyrin repeat K10799 GO:0000209,GO:0000226,GO:0000228,GO:0000242,GO:0000278,GO:0000723,GO:0000781,GO:0000784,GO:0000922,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005643,GO:0005654,GO:0005694,GO:0005737,GO:0005794,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006471,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007063,GO:0007088,GO:0007346,GO:0008104,GO:0008150,GO:0008152,GO:0008270,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0010948,GO:0012505,GO:0015630,GO:0016020,GO:0016043,GO:0016310,GO:0016567,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0022402,GO:0022607,GO:0023051,GO:0023056,GO:0030111,GO:0030162,GO:0030177,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032200,GO:0032204,GO:0032205,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032270,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033046,GO:0033047,GO:0033048,GO:0033365,GO:0034091,GO:0034092,GO:0034182,GO:0034183,GO:0034502,GO:0034613,GO:0034641,GO:0035264,GO:0036211,GO:0040007,GO:0040008,GO:0040014,GO:0042176,GO:0042393,GO:0042592,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043392,GO:0043412,GO:0044085,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044451,GO:0044454,GO:0044464,GO:0045732,GO:0045786,GO:0045839,GO:0045862,GO:0045875,GO:0045893,GO:0045930,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046872,GO:0046914,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048638,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051052,GO:0051053,GO:0051054,GO:0051098,GO:0051100,GO:0051101,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051225,GO:0051239,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051276,GO:0051338,GO:0051347,GO:0051641,GO:0051726,GO:0051783,GO:0051784,GO:0051972,GO:0051973,GO:0051983,GO:0051985,GO:0060249,GO:0060255,GO:0060828,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070198,GO:0070212,GO:0070213,GO:0070647,GO:0070727,GO:0070925,GO:0071704,GO:0071840,GO:0072686,GO:0080090,GO:0090263,GO:0090304,GO:0090364,GO:0097110,GO:0097431,GO:0098687,GO:1901360,GO:1901564,GO:1902680,GO:1902850,GO:1903047,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1903506,GO:1903508,GO:1904353,GO:1904355,GO:1904356,GO:1904357,GO:1904358,GO:1904742,GO:1904743,GO:1904907,GO:1904908,GO:2000058,GO:2000060,GO:2000112,GO:2000278,GO:2000573,GO:2001141,GO:2001251,GO:2001252 2.4.2.30 0.000000000000000008793 98.0
TH1_k127_5416505_19 Protein of unknown function (DUF2892) - - - 0.00000000000000002305 91.0
TH1_k127_5416505_2 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001358 260.0
TH1_k127_5416505_20 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000005041 63.0
TH1_k127_5416505_21 Domain of unknown function (DUF4395) - - - 0.0000004664 58.0
TH1_k127_5416505_22 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189 0.0000006129 61.0
TH1_k127_5416505_3 - - - - 0.000000000000000000000000000000000000000000000000002747 195.0
TH1_k127_5416505_4 - - - - 0.00000000000000000000000000000000000000000000000008078 197.0
TH1_k127_5416505_5 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000008766 175.0
TH1_k127_5416505_6 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000006485 185.0
TH1_k127_5416505_7 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000004877 156.0
TH1_k127_5416505_8 Bacterial PH domain - - - 0.000000000000000000000000000000000000002204 153.0
TH1_k127_5416505_9 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000002747 160.0
TH1_k127_5460127_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1034.0
TH1_k127_5460127_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 514.0
TH1_k127_5460127_10 - - - - 0.0000000000000000000000000000000000000000000002232 176.0
TH1_k127_5460127_11 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000001873 183.0
TH1_k127_5460127_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000001255 166.0
TH1_k127_5460127_13 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000004179 139.0
TH1_k127_5460127_14 MlaD protein K06192 - - 0.000000000000000000000000000000000134 151.0
TH1_k127_5460127_15 Cytidylyltransferase family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000004001 134.0
TH1_k127_5460127_16 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0001812 54.0
TH1_k127_5460127_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 394.0
TH1_k127_5460127_3 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005297 292.0
TH1_k127_5460127_4 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001997 287.0
TH1_k127_5460127_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000003492 282.0
TH1_k127_5460127_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000002947 270.0
TH1_k127_5460127_7 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002315 261.0
TH1_k127_5460127_8 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000009135 247.0
TH1_k127_5460127_9 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000003333 228.0
TH1_k127_5478812_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 350.0
TH1_k127_5478812_1 Methyltransferase domain - - - 0.00000000000000000000000000002623 126.0
TH1_k127_5478812_2 integral membrane protein - - - 0.000000000000000000000000001453 130.0
TH1_k127_5478812_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000001093 85.0
TH1_k127_5498199_0 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 601.0
TH1_k127_5498199_1 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000002667 267.0
TH1_k127_5498199_2 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000006382 202.0
TH1_k127_5498199_3 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000006348 180.0
TH1_k127_5498199_4 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000009052 83.0
TH1_k127_5498199_5 amine dehydrogenase activity - - - 0.000000000006608 79.0
TH1_k127_5498199_7 CAAX protease self-immunity K07052 - - 0.000000001287 72.0
TH1_k127_5498199_8 transcriptional regulator - - - 0.0003561 48.0
TH1_k127_5508185_0 AAA ATPase domain - - - 0.0 1043.0
TH1_k127_5508185_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 5.03e-256 816.0
TH1_k127_5508185_10 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.000000000000000000000000000000000000000000000000000000000005182 212.0
TH1_k127_5508185_11 NAT, N-acetyltransferase, of N-acetylglutamate synthase K22478 - 2.3.1.1,2.7.2.8 0.00000000000000000000000000000000000000000000000000000001829 214.0
TH1_k127_5508185_12 Sulfatase K01130 - 3.1.6.1 0.0002104 48.0
TH1_k127_5508185_13 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0005734 46.0
TH1_k127_5508185_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 1.198e-217 721.0
TH1_k127_5508185_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363 1.7.2.2 3.372e-201 644.0
TH1_k127_5508185_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 507.0
TH1_k127_5508185_5 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 464.0
TH1_k127_5508185_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 449.0
TH1_k127_5508185_7 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 389.0
TH1_k127_5508185_8 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 338.0
TH1_k127_5508185_9 PFAM Aldo keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 317.0
TH1_k127_5540124_0 Dienelactone hydrolase family - - - 0.0 1290.0
TH1_k127_5540124_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 9.577e-295 919.0
TH1_k127_5540124_10 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 487.0
TH1_k127_5540124_11 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 393.0
TH1_k127_5540124_12 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 371.0
TH1_k127_5540124_13 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 362.0
TH1_k127_5540124_14 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 366.0
TH1_k127_5540124_15 coenzyme F420 hydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 357.0
TH1_k127_5540124_16 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 372.0
TH1_k127_5540124_17 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 323.0
TH1_k127_5540124_18 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009212 291.0
TH1_k127_5540124_2 Beta-lactamase - - - 5.272e-216 693.0
TH1_k127_5540124_20 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.000000000000000000000000000000000000000000000000001813 189.0
TH1_k127_5540124_21 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000001883 175.0
TH1_k127_5540124_22 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000007393 186.0
TH1_k127_5540124_23 Transcriptional regulator, Crp Fnr family - - - 0.00000000000000000000000001351 127.0
TH1_k127_5540124_26 Radical SAM K01012 - 2.8.1.6 0.000000000000000005932 97.0
TH1_k127_5540124_27 Putative diguanylate phosphodiesterase - - - 0.0000000000000007349 92.0
TH1_k127_5540124_28 Nitroreductase family - - - 0.000000000000001312 86.0
TH1_k127_5540124_29 aminopeptidase N - - - 0.00000000000002995 85.0
TH1_k127_5540124_3 aspartate--ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 625.0
TH1_k127_5540124_30 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000003988 69.0
TH1_k127_5540124_31 response regulator, receiver - - - 0.0000004166 57.0
TH1_k127_5540124_32 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0008399 49.0
TH1_k127_5540124_4 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 602.0
TH1_k127_5540124_5 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 572.0
TH1_k127_5540124_6 Acetylornithine deacetylase Succinyl-diaminopimelate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 536.0
TH1_k127_5540124_7 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 513.0
TH1_k127_5540124_8 Leukotriene A4 hydrolase, C-terminal K01254 GO:0003674,GO:0003824,GO:0004177,GO:0004301,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016801,GO:0016803,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 505.0
TH1_k127_5540124_9 signal peptide peptidase K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 502.0
TH1_k127_5542807_0 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 418.0
TH1_k127_5542807_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006845 349.0
TH1_k127_5542807_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007101 269.0
TH1_k127_5542807_3 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001938 269.0
TH1_k127_5542807_4 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K03580 GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000001831 239.0
TH1_k127_5542807_5 beta-galactosidase activity K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000008102 196.0
TH1_k127_5560776_0 PFAM Type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 394.0
TH1_k127_5560776_1 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004388 284.0
TH1_k127_5633989_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 9.229e-286 894.0
TH1_k127_5633989_1 ACT domain - - - 0.0001572 55.0
TH1_k127_5655241_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 330.0
TH1_k127_5655241_1 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000003244 216.0
TH1_k127_5674649_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 406.0
TH1_k127_5674649_1 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 302.0
TH1_k127_5674649_2 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002909 260.0
TH1_k127_5674649_3 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.00000000000000000000000000000000000000001637 164.0
TH1_k127_5674649_4 belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000004408 143.0
TH1_k127_5674649_5 - - - - 0.0000001394 64.0
TH1_k127_5694421_0 PFAM Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 548.0
TH1_k127_5694421_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 375.0
TH1_k127_5694421_2 Cytochrome c - - - 0.0000000002923 71.0
TH1_k127_5694421_3 - - - - 0.000000008524 67.0
TH1_k127_5694421_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000002426 60.0
TH1_k127_5707915_0 topoisomerase K02469 - 5.99.1.3 1.502e-266 842.0
TH1_k127_5707915_1 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000001556 213.0
TH1_k127_5707915_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000003703 207.0
TH1_k127_5707915_3 Mg2 transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000006228 183.0
TH1_k127_5707915_4 - - - - 0.0000000000000000000000000000000000000002345 168.0
TH1_k127_5707915_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000004989 166.0
TH1_k127_5707915_6 LTXXQ motif family protein - - - 0.000004306 55.0
TH1_k127_5714829_0 Mycolic acid cyclopropane synthetase - - - 0.000000000203 73.0
TH1_k127_5714829_1 PFAM PEGA domain - - - 0.00000004015 64.0
TH1_k127_5728933_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 3.458e-207 654.0
TH1_k127_5728933_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 594.0
TH1_k127_5728933_10 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000004965 213.0
TH1_k127_5728933_11 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000002439 196.0
TH1_k127_5728933_12 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.0000000000000000000000000000000000000000000005889 191.0
TH1_k127_5728933_13 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000001895 164.0
TH1_k127_5728933_14 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000003062 123.0
TH1_k127_5728933_15 Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.000000000000000001159 102.0
TH1_k127_5728933_16 Thioredoxin-like - - - 0.00000000000000003468 95.0
TH1_k127_5728933_17 UbiA prenyltransferase family K17105 - 2.5.1.42 0.0000000000001109 85.0
TH1_k127_5728933_18 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000324 57.0
TH1_k127_5728933_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 601.0
TH1_k127_5728933_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 434.0
TH1_k127_5728933_4 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 338.0
TH1_k127_5728933_5 Coenzyme A transferase K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 328.0
TH1_k127_5728933_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 321.0
TH1_k127_5728933_7 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 316.0
TH1_k127_5728933_8 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 303.0
TH1_k127_5728933_9 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 294.0
TH1_k127_5746926_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 586.0
TH1_k127_5746926_1 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 546.0
TH1_k127_5746926_2 PFAM Methyltransferase type 11 K03892 - - 0.0000000000000000000000000000000001854 145.0
TH1_k127_5746926_3 Permease, YjgP YjgQ - - - 0.000000000000000001436 92.0
TH1_k127_5768616_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 1.532e-217 703.0
TH1_k127_5768616_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 608.0
TH1_k127_5768616_10 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000218 115.0
TH1_k127_5768616_11 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000004563 102.0
TH1_k127_5768616_12 endoglucanase-related protein, glucosyl hydrolase family 9 protein - - - 0.000000000000004133 86.0
TH1_k127_5768616_2 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 584.0
TH1_k127_5768616_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 509.0
TH1_k127_5768616_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 402.0
TH1_k127_5768616_5 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 398.0
TH1_k127_5768616_6 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000001216 219.0
TH1_k127_5768616_7 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000005832 219.0
TH1_k127_5768616_8 GAF domain - - - 0.0000000000000000000000000000000000000000002348 173.0
TH1_k127_5768616_9 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000215 168.0
TH1_k127_5791350_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 499.0
TH1_k127_5791350_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 421.0
TH1_k127_5791350_10 Protein of unknown function (DUF971) - - - 0.00000000000000000000001513 106.0
TH1_k127_5791350_11 Glycosyl transferase family 2 - - - 0.0000000000000000000001485 112.0
TH1_k127_5791350_2 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 438.0
TH1_k127_5791350_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 378.0
TH1_k127_5791350_4 Domain of unknown function (DUF1972) K12996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 352.0
TH1_k127_5791350_5 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001776 290.0
TH1_k127_5791350_6 Glycosyl transferase, family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000002056 226.0
TH1_k127_5791350_7 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000002045 168.0
TH1_k127_5791350_8 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.00000000000000000000000000000000003484 143.0
TH1_k127_5791350_9 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000002161 149.0
TH1_k127_5801962_0 Sensor protein, DUF3365, HAMP and PAS domain-containing, heme-binding K05962 - 2.7.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 338.0
TH1_k127_5801962_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000002908 250.0
TH1_k127_5802303_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 4.867e-235 761.0
TH1_k127_5802303_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 515.0
TH1_k127_5802303_10 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 297.0
TH1_k127_5802303_11 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000003856 237.0
TH1_k127_5802303_12 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000009171 178.0
TH1_k127_5802303_13 NUDIX domain - - - 0.00000000000000000000000000000000000000003841 171.0
TH1_k127_5802303_14 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.00000000000000000000000000000326 130.0
TH1_k127_5802303_15 PAP2 superfamily - - - 0.0000000000000000000000000008245 131.0
TH1_k127_5802303_16 peptidyl-tyrosine sulfation - - - 0.00000000001514 76.0
TH1_k127_5802303_17 protein conserved in bacteria - - - 0.0000007142 59.0
TH1_k127_5802303_2 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 482.0
TH1_k127_5802303_3 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 428.0
TH1_k127_5802303_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 374.0
TH1_k127_5802303_5 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 336.0
TH1_k127_5802303_6 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 337.0
TH1_k127_5802303_7 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 331.0
TH1_k127_5802303_8 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 315.0
TH1_k127_5802303_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 299.0
TH1_k127_5838461_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.088e-246 796.0
TH1_k127_5838461_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 424.0
TH1_k127_5838461_2 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 353.0
TH1_k127_5838461_3 Cysteine synthase K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000003803 178.0
TH1_k127_5838461_4 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000002794 133.0
TH1_k127_5838461_5 VanZ like family - - - 0.000000008345 69.0
TH1_k127_5988712_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1051.0
TH1_k127_5988712_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000003678 147.0
TH1_k127_5988712_2 Protein of unknown function (DUF2892) - - - 0.0000000000000000000006317 96.0
TH1_k127_5988712_3 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000001346 101.0
TH1_k127_5988712_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000001341 94.0
TH1_k127_5988712_5 Putative regulatory protein - - - 0.00000001204 63.0
TH1_k127_5988712_6 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000006313 59.0
TH1_k127_5989312_0 Peptidase m28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 512.0
TH1_k127_5989312_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 484.0
TH1_k127_5989312_10 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004614 294.0
TH1_k127_5989312_11 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000002206 235.0
TH1_k127_5989312_12 PFAM CBS domain K04767 - - 0.00000000000000000000000000000000000000000000000000000000525 205.0
TH1_k127_5989312_13 phosphate-selective porin O and P - - - 0.0000000000000000000000000000001586 140.0
TH1_k127_5989312_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 488.0
TH1_k127_5989312_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 456.0
TH1_k127_5989312_4 AMP-binding enzyme C-terminal domain K18660,K18661 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 432.0
TH1_k127_5989312_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 353.0
TH1_k127_5989312_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 320.0
TH1_k127_5989312_7 PFAM Major facilitator superfamily K08224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 321.0
TH1_k127_5989312_8 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 314.0
TH1_k127_5989312_9 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005432 281.0
TH1_k127_6087335_0 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 6.64e-219 698.0
TH1_k127_6087335_1 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 517.0
TH1_k127_6087335_2 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 451.0
TH1_k127_6087335_3 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 440.0
TH1_k127_6087335_4 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001034 286.0
TH1_k127_6087335_5 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000007389 206.0
TH1_k127_6087335_6 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000006879 150.0
TH1_k127_6087335_7 Protein of unknown function (DUF3108) - - - 0.000000000000000000000033 114.0
TH1_k127_6087335_8 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000004437 102.0
TH1_k127_6200156_0 TIGRFAM NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein - - - 3.854e-254 803.0
TH1_k127_6200156_1 Peptidase C39 family K06147 - - 8.333e-205 677.0
TH1_k127_6200156_2 Lanthionine synthetase C-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 458.0
TH1_k127_6200156_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 312.0
TH1_k127_6200156_4 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000627 289.0
TH1_k127_6200156_5 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000001092 179.0
TH1_k127_6200156_6 Outer membrane efflux protein - - - 0.0000000000000000000000000003095 132.0
TH1_k127_6200156_7 Outer membrane efflux protein - - - 0.000000000000000000002658 109.0
TH1_k127_6200156_8 Histidine kinase-like ATPase domain - - - 0.00000000000000001871 98.0
TH1_k127_6200156_9 FHA domain containing protein - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.0000000000000006512 84.0
TH1_k127_6209657_0 B12 binding domain - - - 3.752e-247 772.0
TH1_k127_6209657_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 599.0
TH1_k127_6209657_10 Glutaredoxin K03676 - - 0.00000005197 55.0
TH1_k127_6209657_12 CAAX protease self-immunity K07052 - - 0.0003154 51.0
TH1_k127_6209657_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002353 289.0
TH1_k127_6209657_3 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000426 199.0
TH1_k127_6209657_4 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000002942 135.0
TH1_k127_6209657_5 STAS domain K04749 - - 0.00000000000000000000000000000006616 135.0
TH1_k127_6209657_6 Zn peptidase - - - 0.000000000000000000000003534 119.0
TH1_k127_6209657_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000003992 111.0
TH1_k127_6209657_8 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000005951 114.0
TH1_k127_6209657_9 Phosphoglycerate mutase family - - - 0.00000001162 60.0
TH1_k127_6222967_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 590.0
TH1_k127_6222967_1 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 479.0
TH1_k127_6222967_10 - - - - 0.00002251 52.0
TH1_k127_6222967_2 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 315.0
TH1_k127_6222967_3 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004088 263.0
TH1_k127_6222967_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000004638 220.0
TH1_k127_6222967_5 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000001262 224.0
TH1_k127_6222967_6 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000008084 169.0
TH1_k127_6222967_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000001848 146.0
TH1_k127_6222967_8 Pas domain - - - 0.0000000000000000002949 96.0
TH1_k127_6222967_9 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000001625 69.0
TH1_k127_6241480_0 Pirin C-terminal cupin domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 427.0
TH1_k127_6241480_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 429.0
TH1_k127_6241480_2 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 437.0
TH1_k127_6241480_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000162 193.0
TH1_k127_6271876_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001393 289.0
TH1_k127_6290151_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000009633 247.0
TH1_k127_6302477_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000059 203.0
TH1_k127_6302477_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000573 160.0
TH1_k127_6302477_2 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000005158 115.0
TH1_k127_6302477_3 COG1214 Inactive homolog of metal-dependent proteases K14742 - - 0.000000000003146 74.0
TH1_k127_6302477_4 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.2.1.11 0.00000000004446 75.0
TH1_k127_6302477_5 Protein of unknown function (DUF465) - - - 0.0001872 48.0
TH1_k127_6529205_0 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 339.0
TH1_k127_6529205_1 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000002981 211.0
TH1_k127_6529205_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000009917 172.0
TH1_k127_6529205_3 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000007415 117.0
TH1_k127_6598106_0 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000003306 191.0
TH1_k127_6598106_1 Sporulation and spore germination K06298 - - 0.00001816 55.0
TH1_k127_6635682_0 Belongs to the heat shock protein 70 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 605.0
TH1_k127_6635682_1 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 497.0
TH1_k127_6635682_10 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000001034 219.0
TH1_k127_6635682_11 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000002011 112.0
TH1_k127_6635682_12 Glycosyltransferase family 87 K13671 - - 0.0000000000134 77.0
TH1_k127_6635682_13 PQ loop repeat K15383 - - 0.0000000002169 68.0
TH1_k127_6635682_14 Cell division protein FtsQ K03589 - - 0.00000001835 67.0
TH1_k127_6635682_2 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 420.0
TH1_k127_6635682_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 391.0
TH1_k127_6635682_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 392.0
TH1_k127_6635682_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 386.0
TH1_k127_6635682_6 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 409.0
TH1_k127_6635682_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 335.0
TH1_k127_6635682_8 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 314.0
TH1_k127_6635682_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000001039 260.0
TH1_k127_6655034_0 Alkaline phosphatase - - - 0.0000000000000000000000000000000000000000000000000000006658 214.0
TH1_k127_6671263_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 6.359e-254 813.0
TH1_k127_6671263_1 Putative modulator of DNA gyrase K03568 - - 3.414e-247 773.0
TH1_k127_6671263_10 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 329.0
TH1_k127_6671263_11 Microcin C7 resistance K01297 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009050,GO:0009056,GO:0009254,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 310.0
TH1_k127_6671263_12 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004206 238.0
TH1_k127_6671263_13 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000001958 244.0
TH1_k127_6671263_14 Tautomerase enzyme - - - 0.0000000000000000000000000000000000000000000005919 169.0
TH1_k127_6671263_15 Two component regulator propeller - - - 0.000000000000000000000000000000000000005479 163.0
TH1_k127_6671263_16 FAD binding domain - - - 0.00000000000000000000000000000000000307 157.0
TH1_k127_6671263_17 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0000000000000000000000000000008914 125.0
TH1_k127_6671263_18 DinB superfamily - - - 0.00000000000000000000000001241 124.0
TH1_k127_6671263_19 Transposase K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000002426 115.0
TH1_k127_6671263_2 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 3.288e-216 677.0
TH1_k127_6671263_20 Sigma-70, region 4 K03088 - - 0.00000000000000000002562 99.0
TH1_k127_6671263_21 Regulatory protein, FmdB family - - - 0.0000000000000000004564 90.0
TH1_k127_6671263_22 STAS domain - - - 0.00000000000000000177 89.0
TH1_k127_6671263_23 - - - - 0.000000000000000002416 93.0
TH1_k127_6671263_25 phosphorelay signal transduction system - - - 0.00000000000003858 82.0
TH1_k127_6671263_26 - - - - 0.0000000000005392 82.0
TH1_k127_6671263_27 HEAT repeats - - - 0.000000000002282 79.0
TH1_k127_6671263_28 Methyltransferase domain - - - 0.000000000003841 79.0
TH1_k127_6671263_29 - - - - 0.000000001705 71.0
TH1_k127_6671263_3 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 543.0
TH1_k127_6671263_4 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 481.0
TH1_k127_6671263_5 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 413.0
TH1_k127_6671263_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 435.0
TH1_k127_6671263_7 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 388.0
TH1_k127_6671263_8 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 361.0
TH1_k127_6671263_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 340.0
TH1_k127_6758426_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009609 506.0
TH1_k127_6758426_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 454.0
TH1_k127_6758426_2 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 317.0
TH1_k127_6758426_3 - - - - 0.0002475 49.0
TH1_k127_6788300_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 347.0
TH1_k127_6788300_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007981 263.0
TH1_k127_6788300_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000006433 179.0
TH1_k127_6788300_3 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000002012 139.0
TH1_k127_6788300_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000002814 132.0
TH1_k127_6788300_5 GntR family transcriptional regulator K07979 - - 0.00000000000000003413 86.0
TH1_k127_6788300_6 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000004144 71.0
TH1_k127_6788300_7 Type II secretion system (T2SS), protein G K02456 - - 0.00001474 53.0
TH1_k127_6796128_0 Glycosyl hydrolase family 57 K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 457.0
TH1_k127_6796128_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 428.0
TH1_k127_6796128_10 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000007129 118.0
TH1_k127_6796128_11 - - - - 0.0000000000000000000000007452 111.0
TH1_k127_6796128_12 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000003491 108.0
TH1_k127_6796128_13 Transposase IS200 like K07491 - - 0.000000000000000000417 91.0
TH1_k127_6796128_14 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000001356 100.0
TH1_k127_6796128_15 Methyltransferase domain - - - 0.0000000000002074 80.0
TH1_k127_6796128_16 COG3209 Rhs family protein K11021 - - 0.0000000000058 74.0
TH1_k127_6796128_17 PFAM Transposase IS200 like - - - 0.00000000002398 64.0
TH1_k127_6796128_18 Domain of unknown function (DUF4912) K09942 - - 0.0000000004287 73.0
TH1_k127_6796128_19 COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit K02470,K02622 - 5.99.1.3 0.000000213 53.0
TH1_k127_6796128_2 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 322.0
TH1_k127_6796128_20 - - - - 0.00004945 50.0
TH1_k127_6796128_3 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 326.0
TH1_k127_6796128_4 PFAM Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008282 259.0
TH1_k127_6796128_5 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000008882 232.0
TH1_k127_6796128_6 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000002787 208.0
TH1_k127_6796128_7 nicotinamide mononucleotide transporter K03811 - - 0.00000000000000000000000000000000000000000000001728 178.0
TH1_k127_6796128_9 ATPase kinase involved in NAD metabolism - - - 0.000000000000000000000000001628 125.0
TH1_k127_6817018_0 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008604 353.0
TH1_k127_6817018_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 336.0
TH1_k127_6817018_2 DNA recombination K03546,K03631 - - 0.0003504 44.0
TH1_k127_6865206_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.157e-216 704.0
TH1_k127_6865206_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001932 301.0
TH1_k127_6865206_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000203 215.0
TH1_k127_6865206_3 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000005657 210.0
TH1_k127_6865206_4 Serine threonine protein K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000001771 167.0
TH1_k127_6865206_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000006289 149.0
TH1_k127_6865206_6 RDD family - - - 0.0000001681 66.0
TH1_k127_6865206_7 (FHA) domain - - - 0.0000008757 63.0
TH1_k127_6865206_8 PFAM CHAD domain containing protein - - - 0.000002119 59.0
TH1_k127_6865206_9 Carbohydrate-binding family 9 - - - 0.00002338 55.0
TH1_k127_690469_0 Belongs to the malate synthase family K01638 - 2.3.3.9 5.164e-228 721.0
TH1_k127_690469_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 519.0
TH1_k127_690469_10 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000004286 127.0
TH1_k127_690469_11 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000009624 125.0
TH1_k127_690469_12 - - - - 0.0000001463 59.0
TH1_k127_690469_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008463 544.0
TH1_k127_690469_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 437.0
TH1_k127_690469_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 412.0
TH1_k127_690469_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 384.0
TH1_k127_690469_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 316.0
TH1_k127_690469_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000001593 208.0
TH1_k127_690469_8 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.0000000000000000000000000000000000003254 162.0
TH1_k127_690469_9 Peptidase family M23 K21471 - - 0.000000000000000000000000000000007081 149.0
TH1_k127_6949086_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 301.0
TH1_k127_6949086_1 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000002283 95.0
TH1_k127_6949086_2 nuclear chromosome segregation - - - 0.000005545 57.0
TH1_k127_6983455_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 520.0
TH1_k127_6983455_1 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000008808 240.0
TH1_k127_6983455_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000003553 160.0
TH1_k127_6983455_3 FAD binding domain - - - 0.000000000000000000000000000000003706 144.0
TH1_k127_7004231_0 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 604.0
TH1_k127_7004231_1 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 447.0
TH1_k127_7004231_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 365.0
TH1_k127_7004231_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002828 310.0
TH1_k127_7004231_4 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005053 245.0
TH1_k127_7004231_5 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000003046 222.0
TH1_k127_7004231_6 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000001088 99.0
TH1_k127_7004231_7 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000008862 89.0
TH1_k127_7032461_0 Dehydrogenase E1 component K11381 - 1.2.4.4 1.504e-316 983.0
TH1_k127_7032461_1 peptidase K01415,K07386 - 3.4.24.71 9.143e-280 881.0
TH1_k127_7032461_10 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000005267 73.0
TH1_k127_7032461_11 - - - - 0.0000000618 63.0
TH1_k127_7032461_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 538.0
TH1_k127_7032461_3 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 535.0
TH1_k127_7032461_4 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 470.0
TH1_k127_7032461_5 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001119 291.0
TH1_k127_7032461_6 arylsulfatase A K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000004884 226.0
TH1_k127_7032461_7 TonB dependent receptor K16092 - - 0.000000000000000000000000000000000000000000000000000000000003783 230.0
TH1_k127_7032461_8 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000006216 209.0
TH1_k127_7032461_9 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - - 0.000000000000000000000000000000000000000000008903 168.0
TH1_k127_7045713_0 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 382.0
TH1_k127_7045713_1 Type ii and iii secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 309.0
TH1_k127_7045713_2 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000005939 171.0
TH1_k127_7045713_3 general secretion pathway protein K02456 - - 0.0000000000000000000000000000000008689 136.0
TH1_k127_7045713_4 general secretion pathway protein K02456,K02650 - - 0.00000000001178 74.0
TH1_k127_7075272_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003261 276.0
TH1_k127_7075272_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000005108 111.0
TH1_k127_7075272_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000005265 106.0
TH1_k127_7119439_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 354.0
TH1_k127_7119439_1 (FHA) domain - - - 0.000000000273 67.0
TH1_k127_7123946_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 338.0
TH1_k127_7123946_1 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000003828 278.0
TH1_k127_7123946_2 maturation factor XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000009682 173.0
TH1_k127_7123946_3 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000156 108.0
TH1_k127_7123946_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000003579 96.0
TH1_k127_7134879_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 490.0
TH1_k127_7134879_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 453.0
TH1_k127_7134879_10 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003581 264.0
TH1_k127_7134879_11 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000001833 252.0
TH1_k127_7134879_12 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003051 265.0
TH1_k127_7134879_13 Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000006385 254.0
TH1_k127_7134879_14 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000006372 239.0
TH1_k127_7134879_15 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000004666 219.0
TH1_k127_7134879_16 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000005098 178.0
TH1_k127_7134879_17 Putative ABC exporter - - - 0.0000000000000000000000000000000000000000000008958 188.0
TH1_k127_7134879_18 PFAM cytochrome c assembly protein - - - 0.0000000000000000000006611 106.0
TH1_k127_7134879_19 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000004081 82.0
TH1_k127_7134879_2 Involved in the biosynthesis of porphyrin-containing compound K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 446.0
TH1_k127_7134879_20 Peptidase, M23 - - - 0.000000000006569 76.0
TH1_k127_7134879_21 Lanthionine synthetase C family protein - - - 0.00001521 57.0
TH1_k127_7134879_22 - - - - 0.00002003 53.0
TH1_k127_7134879_23 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00002629 55.0
TH1_k127_7134879_24 PEGA domain - - - 0.00004828 56.0
TH1_k127_7134879_25 serine threonine protein kinase - - - 0.0007971 51.0
TH1_k127_7134879_3 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 421.0
TH1_k127_7134879_4 Belongs to the aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 411.0
TH1_k127_7134879_5 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 412.0
TH1_k127_7134879_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 374.0
TH1_k127_7134879_7 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 312.0
TH1_k127_7134879_8 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 312.0
TH1_k127_7134879_9 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 302.0
TH1_k127_7141518_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1035.0
TH1_k127_716502_0 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 410.0
TH1_k127_716502_1 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 353.0
TH1_k127_716502_2 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000003954 193.0
TH1_k127_716502_3 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000008145 166.0
TH1_k127_716502_4 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000008351 155.0
TH1_k127_716502_5 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000003094 145.0
TH1_k127_7172948_0 ABC transporter K06020 - 3.6.3.25 7.684e-229 718.0
TH1_k127_7172948_1 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 348.0
TH1_k127_7172948_2 DNA-binding ferritin-like protein (Oxidative damage protectant) K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000005871 231.0
TH1_k127_7172948_3 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000004757 171.0
TH1_k127_7246756_0 of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001048 221.0
TH1_k127_7246756_1 Pfam:DUF59 - - - 0.000000000000000000000000000000000000000000000005663 190.0
TH1_k127_7246756_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000002573 114.0
TH1_k127_7246756_3 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000095 93.0
TH1_k127_7263308_0 4Fe-4S single cluster domain K06937 - - 1.616e-244 771.0
TH1_k127_7263308_1 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000002114 167.0
TH1_k127_7263308_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000002842 137.0
TH1_k127_7286450_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1330.0
TH1_k127_7286450_1 Ferrous iron transport protein B K04759 - - 6.289e-261 819.0
TH1_k127_7286450_2 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 627.0
TH1_k127_7286450_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 319.0
TH1_k127_7286450_4 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 309.0
TH1_k127_7286450_5 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000402 200.0
TH1_k127_7286450_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000892 192.0
TH1_k127_7286450_7 FeoA K04758 - - 0.00000002786 55.0
TH1_k127_7298755_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 469.0
TH1_k127_7298755_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 411.0
TH1_k127_7298755_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004291 291.0
TH1_k127_7298755_3 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000004451 229.0
TH1_k127_7300991_0 PFAM BNR Asp-box repeat - - - 0.0 1056.0
TH1_k127_7300991_1 GMC oxidoreductase K03333 - 1.1.3.6 2.023e-224 709.0
TH1_k127_7300991_10 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000001044 241.0
TH1_k127_7300991_11 It is involved in the biological process described with L-phenylalanine catabolic process K00500 GO:0000003,GO:0001505,GO:0003008,GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0004510,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006464,GO:0006520,GO:0006558,GO:0006559,GO:0006568,GO:0006569,GO:0006570,GO:0006571,GO:0006576,GO:0006582,GO:0006584,GO:0006586,GO:0006725,GO:0006726,GO:0006732,GO:0006807,GO:0006950,GO:0006979,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008150,GO:0008152,GO:0008340,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009073,GO:0009074,GO:0009095,GO:0009308,GO:0009310,GO:0009712,GO:0009713,GO:0009987,GO:0010259,GO:0016053,GO:0016054,GO:0016491,GO:0016597,GO:0016705,GO:0016714,GO:0017144,GO:0018126,GO:0018958,GO:0019438,GO:0019439,GO:0019538,GO:0019748,GO:0019751,GO:0019752,GO:0031406,GO:0032501,GO:0032502,GO:0034311,GO:0034641,GO:0036094,GO:0036211,GO:0040002,GO:0042133,GO:0042136,GO:0042335,GO:0042402,GO:0042423,GO:0042430,GO:0042436,GO:0042438,GO:0042440,GO:0042441,GO:0042558,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043324,GO:0043412,GO:0043436,GO:0043473,GO:0043474,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046146,GO:0046148,GO:0046189,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0046983,GO:0048037,GO:0048066,GO:0048069,GO:0048856,GO:0050877,GO:0050890,GO:0050896,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901615,GO:1901617,GO:1902221,GO:1902222 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000002983 228.0
TH1_k127_7300991_12 protein of Bacteria UniRef RepID - - - 0.0000000000000000000000000000000000000000000007287 178.0
TH1_k127_7300991_13 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000002179 143.0
TH1_k127_7300991_15 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000002963 117.0
TH1_k127_7300991_16 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000002371 109.0
TH1_k127_7300991_17 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000004485 96.0
TH1_k127_7300991_18 - - - - 0.0000123 57.0
TH1_k127_7300991_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 2.269e-217 677.0
TH1_k127_7300991_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 646.0
TH1_k127_7300991_4 proline dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 552.0
TH1_k127_7300991_5 cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 451.0
TH1_k127_7300991_6 PFAM sodium calcium exchanger membrane region K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 429.0
TH1_k127_7300991_7 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 377.0
TH1_k127_7300991_8 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 326.0
TH1_k127_7300991_9 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 316.0
TH1_k127_7402034_0 PFAM Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 512.0
TH1_k127_7402034_1 surface antigen variable number repeat protein K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 479.0
TH1_k127_7402034_2 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000218 277.0
TH1_k127_7402034_3 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000003673 217.0
TH1_k127_7402034_4 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000009555 170.0
TH1_k127_7402034_5 phosphatase activity K07025 - - 0.0000000000000000000000000000002863 139.0
TH1_k127_7425571_0 extracellular solute-binding protein, family 5 K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 317.0
TH1_k127_7425571_1 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006539 274.0
TH1_k127_7425571_2 - - - - 0.000000000000000000000000000000000000000000000000000006896 208.0
TH1_k127_7425571_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000006931 186.0
TH1_k127_7460436_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 437.0
TH1_k127_7460436_1 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001742 283.0
TH1_k127_7460436_2 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000002947 188.0
TH1_k127_7460436_3 TIGRFAM ATP-binding cassette protein, ChvD family - - - 0.0000000000000000000000000000000000000000000007974 166.0
TH1_k127_7460436_4 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000006381 177.0
TH1_k127_7460436_5 - - - - 0.0000000000000001855 90.0
TH1_k127_7460436_6 Domain of unknown function (DUF4440) - - - 0.000000000000004601 89.0
TH1_k127_7473516_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.489e-317 989.0
TH1_k127_7478352_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 2.083e-317 1002.0
TH1_k127_7478352_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 6.811e-274 850.0
TH1_k127_7478352_2 Cytochrome c554 and c-prime - - - 2.988e-233 744.0
TH1_k127_7478352_3 Protein of unknown function (DUF1254) - - - 4.392e-226 709.0
TH1_k127_7478352_4 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 518.0
TH1_k127_7478352_5 PFAM Cytochrome b b6 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 371.0
TH1_k127_7478352_6 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001069 284.0
TH1_k127_7478352_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000006906 191.0
TH1_k127_7478352_8 Bile acid - - - 0.00000000000000000000000000000000000000000000000001196 207.0
TH1_k127_7478352_9 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.00000000000000000000000000000000000000000002727 182.0
TH1_k127_749659_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 482.0
TH1_k127_749659_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 381.0
TH1_k127_749659_2 VIT family - - - 0.000000000000000000000000000000000000000000000000000000001783 207.0
TH1_k127_749659_3 - - - - 0.0000000000000000000000000000000000000000000000005481 191.0
TH1_k127_749659_4 Glycine-zipper domain - - - 0.0000000002944 65.0
TH1_k127_7496865_0 glycoside hydrolase family 38 K01191 - 3.2.1.24 1.495e-255 859.0
TH1_k127_7496865_1 PEP-utilising enzyme, N-terminal K08483,K11189,K11201 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 499.0
TH1_k127_7496865_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 422.0
TH1_k127_7496865_3 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000001449 250.0
TH1_k127_7496865_4 - - - - 0.000000000000000000000000003502 120.0
TH1_k127_7496865_5 Alpha-1,2-mannosidase - - - 0.000000000000000000001346 113.0
TH1_k127_7496865_6 Lysin motif - - - 0.00000000000000001251 93.0
TH1_k127_7507642_0 NeuB family K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 329.0
TH1_k127_7507642_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000002083 216.0
TH1_k127_7507642_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000008006 219.0
TH1_k127_7507642_3 Subtilase family - - - 0.000000000000002039 91.0
TH1_k127_7553144_0 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 569.0
TH1_k127_7553144_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 543.0
TH1_k127_7553144_10 PFAM Sensors of blue-light using FAD - - - 0.00000000000000008436 88.0
TH1_k127_7553144_11 acyl carrier protein - - - 0.0000000009315 62.0
TH1_k127_7553144_12 PFAM nucleic acid binding, OB-fold, tRNA - - - 0.0000001197 64.0
TH1_k127_7553144_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 501.0
TH1_k127_7553144_3 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 324.0
TH1_k127_7553144_4 Enoyl-(Acyl carrier protein) reductase K11168 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006377 270.0
TH1_k127_7553144_5 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 261.0
TH1_k127_7553144_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000008479 244.0
TH1_k127_7553144_7 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000007711 233.0
TH1_k127_7553144_8 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000006866 184.0
TH1_k127_7553144_9 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000005988 102.0
TH1_k127_7566154_0 His Kinase A (phosphoacceptor) domain K11527 - 2.7.13.3 1.468e-256 831.0
TH1_k127_7566154_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 8.415e-229 734.0
TH1_k127_7566154_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 427.0
TH1_k127_7566154_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 383.0
TH1_k127_7570201_0 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 438.0
TH1_k127_7582672_0 TIGRFAM MazG family protein K02428,K04765 - 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000002416 242.0
TH1_k127_7582672_1 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000158 138.0
TH1_k127_7582672_2 Domain of unknown function (DUF1844) - - - 0.00000000004303 69.0
TH1_k127_7588461_0 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 339.0
TH1_k127_7588461_1 - - - - 0.00000001011 68.0
TH1_k127_7589766_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1394.0
TH1_k127_7589766_1 Amino acid adenylation domain - - - 5.229e-208 664.0
TH1_k127_7589766_10 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002267 265.0
TH1_k127_7589766_11 Histidine kinase K02491,K07698 - 2.7.13.3 0.000000000000000000000000000000000000000000008757 181.0
TH1_k127_7589766_12 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000001227 155.0
TH1_k127_7589766_13 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000000000215 126.0
TH1_k127_7589766_14 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000002774 130.0
TH1_k127_7589766_2 PFAM Cytochrome b b6 domain - - - 2.402e-202 651.0
TH1_k127_7589766_3 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 520.0
TH1_k127_7589766_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 530.0
TH1_k127_7589766_5 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 386.0
TH1_k127_7589766_6 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 360.0
TH1_k127_7589766_7 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 339.0
TH1_k127_7589766_8 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006897 312.0
TH1_k127_7589766_9 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003989 288.0
TH1_k127_7624091_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.113e-281 889.0
TH1_k127_7624091_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.297e-269 857.0
TH1_k127_7624091_10 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000001081 155.0
TH1_k127_7624091_11 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000006084 142.0
TH1_k127_7624091_12 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000008875 101.0
TH1_k127_7624091_13 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000004941 71.0
TH1_k127_7624091_14 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0008150,GO:0040007 3.1.26.5 0.00000000006389 70.0
TH1_k127_7624091_15 stress-induced mitochondrial fusion - - - 0.000000002189 68.0
TH1_k127_7624091_16 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0001124 46.0
TH1_k127_7624091_17 DNA recombination-mediator protein A K04096 - - 0.0004181 48.0
TH1_k127_7624091_18 Tetratricopeptide TPR_2 repeat protein - - - 0.000543 50.0
TH1_k127_7624091_2 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 448.0
TH1_k127_7624091_3 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 406.0
TH1_k127_7624091_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 374.0
TH1_k127_7624091_5 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000001134 235.0
TH1_k127_7624091_6 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000007396 244.0
TH1_k127_7624091_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000004272 225.0
TH1_k127_7624091_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000881 211.0
TH1_k127_7624091_9 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000005378 176.0
TH1_k127_7624135_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1044.0
TH1_k127_7624135_1 AAA domain - - - 3.782e-257 818.0
TH1_k127_7624135_10 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000333 60.0
TH1_k127_7624135_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000003003 63.0
TH1_k127_7624135_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 437.0
TH1_k127_7624135_3 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 368.0
TH1_k127_7624135_4 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 288.0
TH1_k127_7624135_5 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000005339 235.0
TH1_k127_7624135_6 phosphatase activity K01560,K07025,K08723,K20862 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2 0.000000000000000000000000000000000000000000004097 182.0
TH1_k127_7624135_7 histone H2A K63-linked ubiquitination K10914 - - 0.0000000000000000000000000572 119.0
TH1_k127_7624135_8 transporter antisigma-factor antagonist STAS K04749 - - 0.00000000000000000000001633 114.0
TH1_k127_7624135_9 Universal stress protein family - - - 0.0000000000000005432 93.0
TH1_k127_7627660_0 Heat shock 70 kDa protein K04043 - - 1.237e-217 691.0
TH1_k127_7627660_1 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 372.0
TH1_k127_7627660_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 365.0
TH1_k127_7627660_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000008001 232.0
TH1_k127_7627660_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000000001358 136.0
TH1_k127_7627660_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000004536 118.0
TH1_k127_7627660_6 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000004204 106.0
TH1_k127_7627660_7 GTP binding K06883 - - 0.0000000000000000000706 96.0
TH1_k127_764762_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 501.0
TH1_k127_764762_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 287.0
TH1_k127_764762_2 Pantothenate kinase K09680 - 2.7.1.33 0.0000000000000000000000000000005375 141.0
TH1_k127_764762_3 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000005987 119.0
TH1_k127_764762_4 KR domain - - - 0.0000001905 63.0
TH1_k127_7758961_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1054.0
TH1_k127_7758961_1 of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001311 270.0
TH1_k127_7758961_2 Pfam:DUF59 - - - 0.0000000000000000000000000000000000000000000000001087 198.0
TH1_k127_7758961_3 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000001901 113.0
TH1_k127_7758961_4 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000537 93.0
TH1_k127_7758961_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000005111 92.0
TH1_k127_7785459_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 346.0
TH1_k127_7785459_1 Glutamate carboxypeptidase II K01301 - 3.4.17.21 0.000000000000000000000000000000000000000000000000000000000000000000000001397 273.0
TH1_k127_7785459_2 Transferrin receptor-like dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003023 260.0
TH1_k127_7791437_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1641.0
TH1_k127_7791437_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 323.0
TH1_k127_7791437_10 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.0000000000002768 75.0
TH1_k127_7791437_11 Circadian clock protein kaic K08482 - - 0.000008907 59.0
TH1_k127_7791437_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000002026 243.0
TH1_k127_7791437_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000001372 198.0
TH1_k127_7791437_4 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000046 199.0
TH1_k127_7791437_5 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000008765 200.0
TH1_k127_7791437_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000001353 162.0
TH1_k127_7791437_7 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000694 117.0
TH1_k127_7791437_8 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000004224 112.0
TH1_k127_7791437_9 EamA-like transporter family - - - 0.0000000000000000002156 100.0
TH1_k127_7831915_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.866e-278 872.0
TH1_k127_7831915_1 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 347.0
TH1_k127_7831915_10 Serine aminopeptidase, S33 - - - 0.00000000000000002896 93.0
TH1_k127_7831915_11 amine dehydrogenase activity - - - 0.00000000000001247 89.0
TH1_k127_7831915_12 Fatty acid desaturase - - - 0.00000000000001909 84.0
TH1_k127_7831915_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 337.0
TH1_k127_7831915_3 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 336.0
TH1_k127_7831915_4 PFAM glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 347.0
TH1_k127_7831915_5 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000158 209.0
TH1_k127_7831915_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000002131 179.0
TH1_k127_7831915_7 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000001763 181.0
TH1_k127_7831915_8 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000001685 176.0
TH1_k127_7831915_9 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000004548 106.0
TH1_k127_7846638_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 1.402e-275 867.0
TH1_k127_7846638_1 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 9.102e-197 621.0
TH1_k127_7846638_10 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.000000000000002671 83.0
TH1_k127_7846638_11 2Fe-2S -binding domain - - - 0.0000000001188 66.0
TH1_k127_7846638_12 oxidoreductase activity - - - 0.00000002566 67.0
TH1_k127_7846638_13 Thioredoxin-like - - - 0.00003285 55.0
TH1_k127_7846638_14 Resolvase - - - 0.0008146 43.0
TH1_k127_7846638_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 554.0
TH1_k127_7846638_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006601 518.0
TH1_k127_7846638_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000003869 228.0
TH1_k127_7846638_5 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000004269 204.0
TH1_k127_7846638_6 PFAM diacylglycerol kinase catalytic region - - - 0.000000000000000000000000000000000000000000000001422 188.0
TH1_k127_7846638_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000003304 172.0
TH1_k127_7846638_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000802 136.0
TH1_k127_7846638_9 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000007277 129.0
TH1_k127_7849879_0 Domain of unknown function (DUF5107) - - - 6.991e-196 629.0
TH1_k127_7849879_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 484.0
TH1_k127_7849879_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000004722 230.0
TH1_k127_7849879_3 Nad-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000004168 218.0
TH1_k127_7849879_4 ix monomethyl ester oxidative cyclase K04034 GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0033013,GO:0033014,GO:0034641,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000001706 223.0
TH1_k127_7849879_5 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000000000000001263 208.0
TH1_k127_7849879_6 Thioesterase superfamily - - - 0.000000000000000000000000000000000000001917 151.0
TH1_k127_7874009_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 334.0
TH1_k127_7874009_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001083 289.0
TH1_k127_7912950_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 552.0
TH1_k127_7912950_1 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 466.0
TH1_k127_7912950_2 Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 392.0
TH1_k127_7912950_3 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000176 303.0
TH1_k127_7912950_4 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001157 281.0
TH1_k127_7912950_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001342 254.0
TH1_k127_7912950_6 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000002464 123.0
TH1_k127_796503_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 554.0
TH1_k127_796503_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 512.0
TH1_k127_796503_2 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 477.0
TH1_k127_796503_3 Redoxin - - - 0.00000000000000000005725 92.0
TH1_k127_796503_4 PFAM AhpC TSA family K03564 - 1.11.1.15 0.0000000000000431 72.0
TH1_k127_796503_5 Bacteriophage replication gene A protein (GPA) - - - 0.0000000003295 63.0
TH1_k127_796503_6 cell cycle K05589,K12065,K13052 - - 0.0002045 50.0
TH1_k127_798126_0 Beta-lactamase class C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 393.0
TH1_k127_798126_1 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 397.0
TH1_k127_798126_2 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 326.0
TH1_k127_798126_3 short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 296.0
TH1_k127_798126_4 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000001551 241.0
TH1_k127_798126_5 deoxyhypusine monooxygenase activity K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000138 188.0
TH1_k127_798126_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000005036 167.0
TH1_k127_798126_7 - - - - 0.0000000000000000000000000000000000000009621 151.0
TH1_k127_798126_8 Domain of unknown function (DUF4304) - - - 0.00000006976 58.0
TH1_k127_8055020_0 Domain of unknown function DUF302 - - - 0.00000000000000000000000000002782 124.0
TH1_k127_8055020_1 membrane K08972 - - 0.000000000000000000000000001574 124.0
TH1_k127_8055020_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000001493 107.0
TH1_k127_8055020_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000006014 66.0
TH1_k127_8055020_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000008861 76.0
TH1_k127_8075132_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 412.0
TH1_k127_8075132_1 phosphoserine phosphatase activity K07052,K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000001238 190.0
TH1_k127_8075132_2 PFAM ABC transporter transmembrane region K11085 - - 0.000000000000000000000000007485 111.0
TH1_k127_8075132_3 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000001352 102.0
TH1_k127_8075132_4 Domain of unknown function (DUF4412) - - - 0.0000000001731 71.0
TH1_k127_8083303_0 Sulfate permease family - - - 2.197e-215 704.0
TH1_k127_8083303_1 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008727 522.0
TH1_k127_8083303_10 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000009196 153.0
TH1_k127_8083303_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 497.0
TH1_k127_8083303_3 COG NOG10142 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 472.0
TH1_k127_8083303_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 445.0
TH1_k127_8083303_5 Belongs to the glutaminase family K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 404.0
TH1_k127_8083303_6 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 328.0
TH1_k127_8083303_7 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 333.0
TH1_k127_8083303_8 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001783 295.0
TH1_k127_8083303_9 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006964 273.0
TH1_k127_8085895_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.879e-244 785.0
TH1_k127_8085895_1 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 547.0
TH1_k127_8085895_10 permease - - - 0.0000000000000000000000000000000000000004284 171.0
TH1_k127_8085895_11 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000008559 154.0
TH1_k127_8085895_12 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000007783 149.0
TH1_k127_8085895_13 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000178 109.0
TH1_k127_8085895_14 Rieske 2Fe-2S - - - 0.00000000000006388 85.0
TH1_k127_8085895_15 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.0000000000001223 84.0
TH1_k127_8085895_16 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000491 73.0
TH1_k127_8085895_17 Tetratricopeptide repeat - - - 0.00001221 57.0
TH1_k127_8085895_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 525.0
TH1_k127_8085895_3 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 395.0
TH1_k127_8085895_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 366.0
TH1_k127_8085895_5 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 338.0
TH1_k127_8085895_6 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000346 244.0
TH1_k127_8085895_7 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000409 197.0
TH1_k127_8085895_8 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000002011 181.0
TH1_k127_8085895_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000001355 176.0
TH1_k127_8119203_0 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 453.0
TH1_k127_8119203_1 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 326.0
TH1_k127_8119203_2 - - - - 0.000000000000000000000000000000000000005524 149.0
TH1_k127_8119203_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042171,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.51 0.0000000000000000000000000000000000001071 151.0
TH1_k127_8119203_4 HI0933-like protein K07007 - - 0.0000000000000000000000001508 111.0
TH1_k127_8160505_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 352.0
TH1_k127_8160505_1 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000005566 137.0
TH1_k127_8160505_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000001905 152.0
TH1_k127_8160505_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000002799 109.0
TH1_k127_8160505_4 TPM domain - - - 0.0000000000000000000000003438 111.0
TH1_k127_8216683_0 Ribosomal protein S1 K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 598.0
TH1_k127_8216683_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 309.0
TH1_k127_8216683_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000001634 233.0
TH1_k127_8216683_3 Cytidylate kinase K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000001056 186.0
TH1_k127_8216683_4 Protein similar to CwfJ C-terminus 1 K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.0000000000000000000000000000000000000000000001534 174.0
TH1_k127_8216683_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000005763 117.0
TH1_k127_8216683_6 - - - - 0.0001318 53.0
TH1_k127_8218693_0 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 343.0
TH1_k127_8218693_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000001821 173.0
TH1_k127_8218693_2 response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000007062 149.0
TH1_k127_8218693_3 Peptidase m28 - - - 0.000000000000000734 82.0
TH1_k127_8224016_0 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 601.0
TH1_k127_8224016_1 iron-sulfur binding K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 406.0
TH1_k127_8224016_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000008005 247.0
TH1_k127_8224016_3 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000004103 207.0
TH1_k127_8224016_4 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000007968 140.0
TH1_k127_8224016_5 Cytochrome c - - - 0.000000000000000000000000000001622 128.0
TH1_k127_8224016_6 Thioredoxin-like - - - 0.0000000000000000000000000005924 119.0
TH1_k127_8224016_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000001637 68.0
TH1_k127_8224016_8 Transport of potassium into the cell K03549 - - 0.00002354 48.0
TH1_k127_8260110_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 320.0
TH1_k127_8260110_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 316.0
TH1_k127_8260110_10 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000001237 97.0
TH1_k127_8260110_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 300.0
TH1_k127_8260110_3 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000003865 241.0
TH1_k127_8260110_4 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000001503 214.0
TH1_k127_8260110_5 HlyD membrane-fusion protein of T1SS K01993 - - 0.000000000000000000000000000000000000000000001334 190.0
TH1_k127_8260110_6 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000926 156.0
TH1_k127_8260110_7 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000001745 131.0
TH1_k127_8260110_8 - - - - 0.0000000000000000000000000003052 129.0
TH1_k127_8260110_9 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000009258 127.0
TH1_k127_8263063_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 547.0
TH1_k127_8263063_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 488.0
TH1_k127_8263063_2 histidine kinase, HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000001019 251.0
TH1_k127_8263063_3 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000008834 165.0
TH1_k127_8263063_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000006034 132.0
TH1_k127_8263063_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000001036 96.0
TH1_k127_8263063_6 - - - - 0.000000002515 70.0
TH1_k127_8263063_7 Tetratricopeptide repeat - - - 0.00003223 51.0
TH1_k127_8263063_8 Translocator protein, LysE family - - - 0.0004444 50.0
TH1_k127_8269967_0 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 8.274e-219 703.0
TH1_k127_8269967_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.059e-215 692.0
TH1_k127_8269967_10 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000001431 218.0
TH1_k127_8269967_11 Ribosomal protein S5, C-terminal domain K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001059 209.0
TH1_k127_8269967_12 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000003205 187.0
TH1_k127_8269967_13 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000001132 183.0
TH1_k127_8269967_14 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000004248 187.0
TH1_k127_8269967_15 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000002406 174.0
TH1_k127_8269967_16 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000002853 172.0
TH1_k127_8269967_17 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000003163 186.0
TH1_k127_8269967_18 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000319 164.0
TH1_k127_8269967_19 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000003273 161.0
TH1_k127_8269967_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 592.0
TH1_k127_8269967_20 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000003096 157.0
TH1_k127_8269967_21 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000006722 131.0
TH1_k127_8269967_22 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000131 127.0
TH1_k127_8269967_23 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000001682 125.0
TH1_k127_8269967_24 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000007778 111.0
TH1_k127_8269967_25 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000003088 94.0
TH1_k127_8269967_26 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000004003 87.0
TH1_k127_8269967_27 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000008701 85.0
TH1_k127_8269967_28 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000002984 83.0
TH1_k127_8269967_29 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000002068 68.0
TH1_k127_8269967_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 377.0
TH1_k127_8269967_30 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000892 73.0
TH1_k127_8269967_31 Protein of unknown function (DUF503) K09764 - - 0.00000000008998 67.0
TH1_k127_8269967_32 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000005956 57.0
TH1_k127_8269967_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000295 283.0
TH1_k127_8269967_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001507 274.0
TH1_k127_8269967_6 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000009081 275.0
TH1_k127_8269967_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001062 260.0
TH1_k127_8269967_8 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000009985 244.0
TH1_k127_8269967_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000006417 207.0
TH1_k127_8309780_0 Urocanase C-terminal domain K01712 - 4.2.1.49 6.559e-243 764.0
TH1_k127_8309780_1 PFAM phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 308.0
TH1_k127_8309780_2 PFAM Patatin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000901 265.0
TH1_k127_8309780_3 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000001823 219.0
TH1_k127_8309780_4 PHB/PHA accumulation regulator DNA-binding domain - - - 0.00002268 54.0
TH1_k127_8360794_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 347.0
TH1_k127_8360794_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 342.0
TH1_k127_8360794_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003838 290.0
TH1_k127_8360794_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000008797 184.0
TH1_k127_8360794_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000003164 165.0
TH1_k127_8360794_5 non-canonical purine NTP pyrophosphatase, RdgB HAM1 family K02428 - 3.6.1.66 0.0000000000000000000000000000000002475 139.0
TH1_k127_8360794_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000008234 133.0
TH1_k127_8383850_0 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000002993 236.0
TH1_k127_8383850_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000003136 194.0
TH1_k127_8383850_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000001934 185.0
TH1_k127_8383850_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000007791 182.0
TH1_k127_8383850_4 Outer membrane efflux protein - - - 0.00000000000000000000000002088 124.0
TH1_k127_8467899_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 544.0
TH1_k127_8467899_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 532.0
TH1_k127_8467899_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 352.0
TH1_k127_8467899_3 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 302.0
TH1_k127_8467899_4 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000002298 173.0
TH1_k127_8467899_5 Winged helix DNA-binding domain - - - 0.00000000000000000000000000002335 128.0
TH1_k127_8467899_6 Tetratricopeptide repeat - - - 0.000000000000000000000000002873 130.0
TH1_k127_8467899_7 ketosteroid isomerase - - - 0.0000005351 61.0
TH1_k127_8496036_0 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 557.0
TH1_k127_8496036_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 499.0
TH1_k127_8496036_10 OmpW family K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000006488 57.0
TH1_k127_8496036_2 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 426.0
TH1_k127_8496036_3 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 416.0
TH1_k127_8496036_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 400.0
TH1_k127_8496036_5 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003642 259.0
TH1_k127_8496036_6 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009004 256.0
TH1_k127_8496036_7 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000006349 229.0
TH1_k127_8496036_8 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000001576 166.0
TH1_k127_8496036_9 Membrane - - - 0.00000000000000000000000000000000004287 156.0
TH1_k127_8517745_0 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 438.0
TH1_k127_8517745_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000008845 117.0
TH1_k127_8519169_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 3.98e-297 919.0
TH1_k127_8519169_1 ERAP1-like C-terminal domain K01263 - 3.4.11.14 1.403e-215 711.0
TH1_k127_8519169_10 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000006446 171.0
TH1_k127_8519169_11 YCII-related domain K09780 - - 0.000000000000000000000000000000000000000001581 157.0
TH1_k127_8519169_12 nickel cation binding K04651 - - 0.00000000000000001166 95.0
TH1_k127_8519169_13 Hydrogenase expression formation protein K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000006197 85.0
TH1_k127_8519169_14 Protein of unknown function (DUF4019) - - - 0.00000000002401 77.0
TH1_k127_8519169_2 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 535.0
TH1_k127_8519169_3 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 426.0
TH1_k127_8519169_4 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 441.0
TH1_k127_8519169_5 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 337.0
TH1_k127_8519169_6 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000113 287.0
TH1_k127_8519169_7 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000004291 233.0
TH1_k127_8519169_8 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000002174 178.0
TH1_k127_8519169_9 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000002249 178.0
TH1_k127_8579343_0 PFAM Surface antigen variable number repeat K07277 - - 0.0000000000000000000000004125 119.0
TH1_k127_8579343_1 long-chain fatty acid transport protein - - - 0.000003406 60.0
TH1_k127_8605329_0 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000006731 246.0
TH1_k127_8605329_1 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000009283 145.0
TH1_k127_8605329_2 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000004982 106.0
TH1_k127_8605329_3 formate dehydrogenase K00127 - - 0.00000000000000392 89.0
TH1_k127_8642576_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1183.0
TH1_k127_8642576_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 1.691e-195 627.0
TH1_k127_8642576_10 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000002461 217.0
TH1_k127_8642576_11 Riboflavin synthase K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000000000005879 192.0
TH1_k127_8642576_12 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000003305 186.0
TH1_k127_8642576_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000006752 132.0
TH1_k127_8642576_14 biopolymer transport protein K03559,K03560 - - 0.0000000000000000000000009877 108.0
TH1_k127_8642576_15 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000001593 121.0
TH1_k127_8642576_16 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000001855 107.0
TH1_k127_8642576_17 TPR repeat - - - 0.0000000000000000001431 101.0
TH1_k127_8642576_18 energy transducer activity K03832 - - 0.00000000000001068 83.0
TH1_k127_8642576_2 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 9.522e-195 622.0
TH1_k127_8642576_3 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 395.0
TH1_k127_8642576_4 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 360.0
TH1_k127_8642576_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 321.0
TH1_k127_8642576_6 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000744 325.0
TH1_k127_8642576_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 302.0
TH1_k127_8642576_8 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000003256 213.0
TH1_k127_8642576_9 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000001932 222.0
TH1_k127_8643912_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 451.0
TH1_k127_8643912_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000001021 251.0
TH1_k127_8643912_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000000000126 157.0
TH1_k127_8643912_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000000000000000001252 136.0
TH1_k127_8643912_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000008115 94.0
TH1_k127_8643912_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000007908 73.0
TH1_k127_8643912_6 phosphatase activity K01560,K07025,K20866,K21063 GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104,3.8.1.2 0.0000000000008446 78.0
TH1_k127_8663953_0 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 313.0
TH1_k127_8663953_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005025 293.0
TH1_k127_8663953_2 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000001834 171.0
TH1_k127_8663953_3 arylsulfatase A - - - 0.0000000000000000000000000000000000000000003482 176.0
TH1_k127_8663953_4 Class I peptide chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000002465 107.0
TH1_k127_8663953_5 Translation initiation factor SUI1 K03113 - - 0.000000000000000000000004114 107.0
TH1_k127_8663953_6 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000005214 115.0
TH1_k127_8663953_7 Tetratricopeptide repeat - - - 0.0000002112 64.0
TH1_k127_8663953_8 Carboxypeptidase regulatory-like domain - - - 0.0000002786 64.0
TH1_k127_87027_0 Dehydratase family K01687 - 4.2.1.9 1.076e-230 730.0
TH1_k127_87027_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 3.736e-210 667.0
TH1_k127_87027_2 Acetolactate synthase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 421.0
TH1_k127_87027_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000001804 241.0
TH1_k127_87027_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000001842 233.0
TH1_k127_87027_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000003829 195.0
TH1_k127_87027_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000003945 137.0
TH1_k127_87027_7 SnoaL-like domain - - - 0.0000000000000000000000000000004215 126.0
TH1_k127_8723151_0 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 319.0
TH1_k127_8723151_1 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 338.0
TH1_k127_8723151_2 chorismate binding enzyme K01665,K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000003546 217.0
TH1_k127_8723151_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000008101 205.0
TH1_k127_8723151_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000522 196.0
TH1_k127_8723151_5 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000000001035 123.0
TH1_k127_8723151_6 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826,K02619 - 2.6.1.42,4.1.3.38 0.0000004241 63.0
TH1_k127_8778117_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1257.0
TH1_k127_8778117_1 DNA topoisomerase K02470,K02622 - 5.99.1.3 1.039e-274 856.0
TH1_k127_8778117_2 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 589.0
TH1_k127_8778117_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005736 288.0
TH1_k127_8778117_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001387 289.0
TH1_k127_8778117_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000002366 215.0
TH1_k127_8778117_6 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.000000000000000000000000000000000000001062 171.0
TH1_k127_8778117_7 Uncharacterised protein family (UPF0227) K07000 - - 0.000000002255 68.0
TH1_k127_8778117_8 peptidyl-tyrosine sulfation - - - 0.00008729 50.0
TH1_k127_8807629_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 507.0
TH1_k127_8807629_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000008584 102.0
TH1_k127_8807629_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000289 85.0
TH1_k127_8833641_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1063.0
TH1_k127_8833641_1 Magnesium chelatase, subunit ChlI K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 494.0
TH1_k127_8833641_2 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001449 281.0
TH1_k127_8833641_3 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001463 272.0
TH1_k127_8833641_4 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000001011 177.0
TH1_k127_8860807_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 500.0
TH1_k127_8860807_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 475.0
TH1_k127_8860807_2 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 324.0
TH1_k127_8860807_3 Hexosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003462 269.0
TH1_k127_8860807_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000001648 226.0
TH1_k127_8860807_5 Met-10+ like-protein - - - 0.00000000000000000000000000006637 134.0
TH1_k127_8860807_6 Uncharacterised nucleotidyltransferase - - - 0.000000000004392 78.0
TH1_k127_8863893_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 555.0
TH1_k127_8863893_1 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 537.0
TH1_k127_8863893_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 405.0
TH1_k127_8863893_3 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000001765 235.0
TH1_k127_8863893_4 Heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000000001182 186.0
TH1_k127_8863893_5 diguanylate cyclase - - - 0.0000000000000000000000000000000000004392 162.0
TH1_k127_8882375_0 PFAM ABC transporter - - - 4.769e-255 810.0
TH1_k127_8882375_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.499e-239 749.0
TH1_k127_8882375_10 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 475.0
TH1_k127_8882375_11 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 344.0
TH1_k127_8882375_12 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005468 319.0
TH1_k127_8882375_13 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006289 282.0
TH1_k127_8882375_14 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005455 260.0
TH1_k127_8882375_15 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001795 259.0
TH1_k127_8882375_16 Two component transcriptional regulator, winged helix family K07667 - - 0.00000000000000000000000000000000000000000000000000000000005704 226.0
TH1_k127_8882375_17 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000003398 227.0
TH1_k127_8882375_18 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000002049 195.0
TH1_k127_8882375_19 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000000000000003412 179.0
TH1_k127_8882375_2 FGGY family of carbohydrate kinases, N-terminal domain - - - 3.537e-234 735.0
TH1_k127_8882375_20 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000001587 187.0
TH1_k127_8882375_21 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.00000000000000000000000000000000000000000006414 165.0
TH1_k127_8882375_22 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00000000000000000000000000000000000000341 160.0
TH1_k127_8882375_23 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000005819 149.0
TH1_k127_8882375_24 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000000007308 139.0
TH1_k127_8882375_25 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.000000000000000000000000000000000009102 139.0
TH1_k127_8882375_26 - - - - 0.000000000000000000000000000001111 132.0
TH1_k127_8882375_27 CBS domain - - - 0.0000000000000000005673 92.0
TH1_k127_8882375_28 cheY-homologous receiver domain - - - 0.000000000000003999 82.0
TH1_k127_8882375_29 aspartate kinase activity - - - 0.000000000001702 73.0
TH1_k127_8882375_3 Amino acid permease - - - 3.914e-225 719.0
TH1_k127_8882375_30 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.0000000003521 70.0
TH1_k127_8882375_4 Glycogen debranching enzyme - - - 5.829e-215 686.0
TH1_k127_8882375_5 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 8.754e-195 624.0
TH1_k127_8882375_6 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 632.0
TH1_k127_8882375_7 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 594.0
TH1_k127_8882375_8 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 585.0
TH1_k127_8882375_9 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 588.0
TH1_k127_8906062_0 response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007717 286.0
TH1_k127_8906062_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000001467 247.0
TH1_k127_8906062_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000002277 186.0
TH1_k127_8906062_3 Protein tyrosine kinase - - - 0.000000000000000000000003772 117.0
TH1_k127_8906062_4 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000007134 99.0
TH1_k127_8906062_5 antisigma factor binding - - - 0.0000000000000000000125 96.0
TH1_k127_8906062_6 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000003246 61.0
TH1_k127_891590_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.459e-239 752.0
TH1_k127_891590_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 487.0
TH1_k127_891590_10 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000003097 126.0
TH1_k127_891590_12 Protein of unknown function DUF58 - - - 0.0000000000000000000000002088 120.0
TH1_k127_891590_13 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000002373 112.0
TH1_k127_891590_14 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000004712 60.0
TH1_k127_891590_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 454.0
TH1_k127_891590_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 316.0
TH1_k127_891590_4 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001127 284.0
TH1_k127_891590_5 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000181 278.0
TH1_k127_891590_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000443 233.0
TH1_k127_891590_7 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000002012 232.0
TH1_k127_891590_8 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000005323 216.0
TH1_k127_891590_9 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000006022 188.0
TH1_k127_8965762_0 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 394.0
TH1_k127_8965762_1 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 364.0
TH1_k127_8965762_2 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 327.0
TH1_k127_8965762_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000001891 231.0
TH1_k127_8965762_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000005264 212.0
TH1_k127_8965762_5 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000003935 173.0
TH1_k127_8965762_6 peroxiredoxin activity - - - 0.000000000000000000000000000000000000001582 163.0
TH1_k127_8965762_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000001613 116.0
TH1_k127_8965762_8 cell redox homeostasis - - - 0.000000000000000001069 98.0
TH1_k127_8982279_0 cellulose binding - - - 6.929e-273 872.0
TH1_k127_8982279_1 oligopeptide transport K03305 - - 3.714e-222 713.0
TH1_k127_8982279_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000001568 188.0
TH1_k127_8982279_11 DinB family - - - 0.00000000000000000000000000000000004567 141.0
TH1_k127_8982279_12 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000002244 117.0
TH1_k127_8982279_13 RNA recognition motif - - - 0.000000000000000000000008439 103.0
TH1_k127_8982279_2 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 510.0
TH1_k127_8982279_3 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 505.0
TH1_k127_8982279_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 439.0
TH1_k127_8982279_5 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 429.0
TH1_k127_8982279_6 Alkane 1-monooxygenase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 340.0
TH1_k127_8982279_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 349.0
TH1_k127_8982279_8 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 316.0
TH1_k127_8982279_9 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000009076 221.0
TH1_k127_8988028_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 542.0
TH1_k127_8988028_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 394.0
TH1_k127_8988028_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000004839 191.0
TH1_k127_8988028_3 PFAM MgtC family K07507 - - 0.0000000000000000000000000004516 119.0
TH1_k127_8988028_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000006521 115.0
TH1_k127_8988028_5 Transcription factor zinc-finger K09981 - - 0.00000000000000000000000123 119.0
TH1_k127_8988028_6 Tetratricopeptide repeat - - - 0.0009392 49.0
TH1_k127_906414_0 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 539.0
TH1_k127_906414_1 receptor K16087 - - 0.0000000000368 74.0
TH1_k127_9071040_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 516.0
TH1_k127_9071040_1 PTS system, fructose subfamily, IIC subunit K02768,K02769,K02770,K11203 - 2.7.1.202 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 425.0
TH1_k127_9071040_2 Possible lysine decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 324.0
TH1_k127_9071040_3 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 309.0
TH1_k127_9071040_4 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000003165 214.0
TH1_k127_9071040_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000003755 178.0
TH1_k127_9071040_6 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000006091 119.0
TH1_k127_9071040_7 PFAM phosphotransferase system PTS fructose-specific IIB subunit K02769,K11202 - 2.7.1.202 0.0000000000000000000000009105 120.0
TH1_k127_9071040_8 Zincin-like metallopeptidase - - - 0.00000000000000000000003646 106.0
TH1_k127_9071040_9 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483,K11189,K11201 - 2.7.3.9 0.00000000000002375 81.0
TH1_k127_9072314_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 1.988e-215 717.0
TH1_k127_9072314_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 2.765e-201 636.0
TH1_k127_9072314_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 514.0
TH1_k127_9072314_3 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 453.0
TH1_k127_9072314_4 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009012 417.0
TH1_k127_9072314_5 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 317.0
TH1_k127_9072314_6 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000892 289.0
TH1_k127_9072314_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000395 230.0
TH1_k127_9072314_8 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000003681 200.0
TH1_k127_9072314_9 Stage II sporulation protein K06381 - - 0.0000000000000001149 91.0
TH1_k127_9082297_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 380.0
TH1_k127_9082297_1 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 373.0
TH1_k127_9082297_2 Peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009372 268.0
TH1_k127_9082297_3 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000006068 239.0
TH1_k127_9082297_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000001568 223.0
TH1_k127_9082297_5 TIGRFAM histidinol phosphate phosphatase HisJ family K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000001781 165.0
TH1_k127_9082297_6 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000003349 176.0
TH1_k127_9082297_7 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000009552 143.0
TH1_k127_9082297_8 Phosphoglycerate mutase family K08296 - - 0.000000000000005853 82.0
TH1_k127_9084005_0 TIGRFAM Na H antiporter, bacterial form K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 456.0
TH1_k127_9084005_1 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 454.0
TH1_k127_9084005_2 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 379.0
TH1_k127_9084005_3 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000001014 132.0
TH1_k127_9091379_0 amino acid K03294 - - 5.826e-272 842.0
TH1_k127_9091379_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 457.0
TH1_k127_9091379_2 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000009075 280.0
TH1_k127_9091379_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000006288 64.0
TH1_k127_9102637_0 Heat shock 70 kDa protein K04043 - - 3.827e-288 896.0
TH1_k127_9102637_1 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000002131 196.0
TH1_k127_9102637_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000001842 139.0
TH1_k127_9107681_0 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 589.0
TH1_k127_9107681_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002691 229.0
TH1_k127_9107681_2 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000006964 236.0
TH1_k127_9107681_4 Ion channel - - - 0.0000000000001964 79.0
TH1_k127_9107681_5 YMGG-like Gly-zipper - - - 0.00000000006862 70.0
TH1_k127_9107681_6 Putative regulatory protein - - - 0.000000000747 64.0
TH1_k127_9107681_7 Belongs to the ompA family K03286 - - 0.0001139 56.0
TH1_k127_9124481_0 cellulose binding - - - 0.0 1140.0
TH1_k127_9124481_1 - - - - 0.0 999.0
TH1_k127_9124481_2 Hydrolase CocE NonD family - - - 2.863e-313 971.0
TH1_k127_9124481_3 acyl-CoA dehydrogenase - - - 2.837e-241 761.0
TH1_k127_9124481_4 Phosphopantetheine attachment site - - - 1.52e-213 684.0
TH1_k127_9124481_5 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000009788 209.0
TH1_k127_9124481_6 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000002846 197.0
TH1_k127_9124481_7 - - - - 0.00000000001423 74.0
TH1_k127_9160003_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.857e-254 808.0
TH1_k127_9160003_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.32e-229 726.0
TH1_k127_9160003_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006313 283.0
TH1_k127_9160003_11 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001014 284.0
TH1_k127_9160003_12 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004169 287.0
TH1_k127_9160003_13 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000005439 212.0
TH1_k127_9160003_14 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000002862 183.0
TH1_k127_9160003_16 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000001133 185.0
TH1_k127_9160003_17 - - - - 0.00000000000000000000000000000000000622 150.0
TH1_k127_9160003_18 Response regulator receiver K02658 - - 0.0000000000000000000000000978 118.0
TH1_k127_9160003_19 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000004075 102.0
TH1_k127_9160003_2 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 513.0
TH1_k127_9160003_20 - - - - 0.00000000000000002508 95.0
TH1_k127_9160003_21 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000007797 93.0
TH1_k127_9160003_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 510.0
TH1_k127_9160003_4 ABC transporter, transmembrane K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 516.0
TH1_k127_9160003_5 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 462.0
TH1_k127_9160003_6 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 429.0
TH1_k127_9160003_7 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 378.0
TH1_k127_9160003_8 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 373.0
TH1_k127_9160003_9 Pyruvate kinase, barrel domain K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000372 305.0
TH1_k127_9231755_0 Sugar (and other) transporter - - - 9.738e-242 759.0
TH1_k127_9231755_1 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 6.796e-231 743.0
TH1_k127_9231755_10 Polymer-forming cytoskeletal - - - 0.0000000000000000008304 92.0
TH1_k127_9231755_2 Belongs to the aldehyde dehydrogenase family K22187 - - 2.792e-216 689.0
TH1_k127_9231755_3 Aminotransferase class I and II K00812,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 419.0
TH1_k127_9231755_4 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 377.0
TH1_k127_9231755_5 CBS domain containing protein K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 342.0
TH1_k127_9231755_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000004757 250.0
TH1_k127_9231755_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000008255 203.0
TH1_k127_9231755_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000003549 138.0
TH1_k127_9231755_9 Universal stress protein - - - 0.0000000000000000007753 93.0
TH1_k127_9312171_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 316.0
TH1_k127_9312171_1 Bacterial Ig-like domain (group 3) K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003081 280.0
TH1_k127_9312171_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004283 278.0
TH1_k127_9312171_3 protein with a C-terminal OMP (outer membrane protein) domain - - - 0.0000000001504 74.0
TH1_k127_9351635_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000006664 68.0
TH1_k127_9368912_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 383.0
TH1_k127_9368912_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000002186 179.0
TH1_k127_9368912_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000003892 170.0
TH1_k127_9368912_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0002493 52.0
TH1_k127_9383023_0 oxidoreductase activity - - - 7.303e-272 844.0
TH1_k127_9383023_1 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000000000000000000000002772 171.0
TH1_k127_9383023_2 Male sterility protein - - - 0.0000000000005983 72.0
TH1_k127_9383023_3 - - - - 0.0000000005745 71.0
TH1_k127_9395364_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 400.0
TH1_k127_9395364_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003555 276.0
TH1_k127_9395364_2 Radical SAM - - - 0.0000000000000000000000000000000000002261 143.0
TH1_k127_9395364_3 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000004391 145.0
TH1_k127_9395364_4 CAAX protease self-immunity - - - 0.0000001023 62.0
TH1_k127_9461735_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.237e-268 877.0
TH1_k127_9461735_1 Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 444.0
TH1_k127_9461735_2 Cytochrome c assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000007049 214.0
TH1_k127_9461735_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000001812 129.0
TH1_k127_9461735_4 Dodecin K09165 - - 0.000000000000000000000000827 105.0
TH1_k127_9461735_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.000000000000009825 78.0
TH1_k127_9461735_6 - - - - 0.000000001537 63.0
TH1_k127_9461735_7 Involved in the tonB-independent uptake of proteins - - - 0.00001043 49.0
TH1_k127_950382_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 515.0
TH1_k127_950382_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009916 279.0
TH1_k127_950382_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000004279 177.0
TH1_k127_950382_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000001209 158.0
TH1_k127_950382_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000001469 94.0
TH1_k127_950382_5 - - - - 0.0000000000003755 83.0
TH1_k127_950382_6 Outer membrane protein beta-barrel domain - - - 0.000000258 63.0
TH1_k127_9509948_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 424.0
TH1_k127_9509948_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 332.0
TH1_k127_9509948_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000001623 188.0
TH1_k127_9509948_3 depolymerase K03932 - - 0.000000000000000000000000000000000000008503 154.0
TH1_k127_9509948_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000004214 98.0
TH1_k127_9515473_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 436.0
TH1_k127_9515473_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 310.0
TH1_k127_9515473_2 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000003614 258.0
TH1_k127_9515473_3 Predicted membrane protein (DUF2142) - - - 0.0000000000000000000000000000000000000000000001822 186.0
TH1_k127_9515473_4 PFAM Radical SAM - - - 0.0000000000000000000000000000000006448 138.0
TH1_k127_9515473_5 TM2 domain - - - 0.0000000000000000000008653 100.0
TH1_k127_9515473_6 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000001964 91.0
TH1_k127_9515473_7 Putative MetA-pathway of phenol degradation - - - 0.00001174 55.0
TH1_k127_9515473_8 -O-antigen - - - 0.00002025 56.0
TH1_k127_9523635_0 Elongation factor G, domain IV K02355 - - 9.033e-203 653.0
TH1_k127_9523635_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004119 286.0
TH1_k127_9523635_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000002307 270.0
TH1_k127_9523635_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000002872 247.0
TH1_k127_9523635_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000001101 177.0
TH1_k127_9524222_0 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 529.0
TH1_k127_9524222_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003092 270.0
TH1_k127_9524222_2 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000000006287 227.0
TH1_k127_9524222_3 Membrane - - - 0.00000000000000000000000000000002094 147.0
TH1_k127_958520_0 ATP-dependent helicase activity K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 430.0
TH1_k127_958520_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 320.0
TH1_k127_958520_2 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000003737 231.0
TH1_k127_958520_3 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000005055 235.0
TH1_k127_958520_4 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000001253 186.0
TH1_k127_958520_5 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000001372 146.0
TH1_k127_958520_6 - - - - 0.000000000000000000000000000000000008543 149.0
TH1_k127_958520_7 DnaJ-class molecular chaperone with C-terminal Zn finger domain - - - 0.000000000007916 74.0
TH1_k127_958520_8 Domain of unknown function (DUF4115) - - - 0.00000000001978 67.0
TH1_k127_9597499_0 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007235 535.0
TH1_k127_9597499_1 TonB-dependent Receptor Plug Domain K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 381.0
TH1_k127_9597499_11 VanZ like family - - - 0.00001861 57.0
TH1_k127_9597499_2 PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008622 290.0
TH1_k127_9597499_3 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001085 295.0
TH1_k127_9597499_4 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000366 268.0
TH1_k127_9597499_5 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002352 266.0
TH1_k127_9597499_6 helix_turn_helix, Lux Regulon K02282 - - 0.000000000000000000000000000000000000000000000000001406 190.0
TH1_k127_9597499_7 histidine kinase dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000003347 187.0
TH1_k127_9597499_8 Multicopper K06324 - 1.16.3.3 0.0000000000000000000000000000000000000003921 164.0
TH1_k127_9597499_9 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000004345 171.0
TH1_k127_961577_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 471.0
TH1_k127_961577_1 carbamate kinase K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 430.0
TH1_k127_961577_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 327.0
TH1_k127_961577_3 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000002685 166.0
TH1_k127_961577_4 - - - - 0.000000000000000000000000000004897 128.0
TH1_k127_961577_5 - - - - 0.0000000000000000000000004074 116.0
TH1_k127_961577_6 - - - - 0.00000000001065 71.0
TH1_k127_9667164_0 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000001123 227.0
TH1_k127_9667164_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000003176 144.0
TH1_k127_9667164_3 anion-transporting ATPase - - - 0.000000000004929 78.0
TH1_k127_9690359_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 396.0
TH1_k127_9690359_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 371.0
TH1_k127_9690359_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000007185 231.0
TH1_k127_9690359_3 Belongs to the ompA family - - - 0.00000000000000000000000000000000005683 143.0
TH1_k127_9690359_4 von Willebrand factor, type A - - - 0.0000000000000000002717 98.0
TH1_k127_9690359_5 phosphoglycerate mutase K15634 - 5.4.2.12 0.0000000000000000004237 91.0
TH1_k127_971483_0 PFAM short-chain dehydrogenase reductase SDR K15314 - - 0.0 2556.0
TH1_k127_971483_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 413.0
TH1_k127_971483_10 Thioesterase-like superfamily K07107 - - 0.0000000000000001732 93.0
TH1_k127_971483_11 helix_turn_helix, Lux Regulon - - - 0.000000002808 69.0
TH1_k127_971483_12 Protein of unknown function (DUF1579) - - - 0.0000008022 59.0
TH1_k127_971483_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 353.0
TH1_k127_971483_3 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000001319 257.0
TH1_k127_971483_4 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000001439 248.0
TH1_k127_971483_5 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000002509 219.0
TH1_k127_971483_6 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000002915 205.0
TH1_k127_971483_7 Histidine kinase - - - 0.0000000000000000000000000000001804 139.0
TH1_k127_971483_8 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000000000000000000000000007072 133.0
TH1_k127_971483_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000001232 118.0
TH1_k127_97767_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001619 279.0
TH1_k127_97767_1 Belongs to the peptidase S8 family K12287,K12516,K20276 - - 0.0000000000002072 74.0