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Overview

ID MAG03870
Name TH1_bin.45
Sample SMP0100
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order SZUA-229
Family SZUA-229
Genus JACPVK01
Species
Assembly information
Completeness (%) 88.3
Contamination (%) 1.72
GC content (%) 51.0
N50 (bp) 11,127
Genome size (bp) 2,362,788

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2308

Gene name Description KEGG GOs EC E-value Score Sequence
TH1_k127_10235_0 COG2010 Cytochrome c, mono- and diheme variants - - - 5.651e-207 657.0
TH1_k127_10235_1 Radical SAM superfamily K06139 - - 2.479e-205 645.0
TH1_k127_10235_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 304.0
TH1_k127_10235_3 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006492 245.0
TH1_k127_10235_4 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000000000001165 178.0
TH1_k127_10235_5 transcriptional regulator AsnC family - - - 0.00000000000000000000000000000008766 124.0
TH1_k127_10235_6 Phage tail sheath C-terminal domain K06907 - - 0.0000000000000000000000000000007775 127.0
TH1_k127_10235_7 - - - - 0.000000000000000000000249 100.0
TH1_k127_10235_8 peptidylprolyl isomerase K01802 - 5.2.1.8 0.0000000000000968 81.0
TH1_k127_1060172_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 1.542e-313 978.0
TH1_k127_1060172_1 FAD dependent oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 567.0
TH1_k127_1060172_10 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 287.0
TH1_k127_1060172_11 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007951 283.0
TH1_k127_1060172_12 PFAM MgtC SapB transporter K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004958 272.0
TH1_k127_1060172_13 Outer Membrane Lipoprotein K03098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001085 266.0
TH1_k127_1060172_14 Transposase K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000878 255.0
TH1_k127_1060172_15 Protein of unknown function (DUF2878) - - - 0.000000000000000000000000000000000000000000000000001733 187.0
TH1_k127_1060172_16 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000008315 186.0
TH1_k127_1060172_17 PFAM thioesterase superfamily K19222 - 3.1.2.28 0.0000000000000000000000000000000000000000000000001254 182.0
TH1_k127_1060172_18 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000001228 175.0
TH1_k127_1060172_19 CoA binding domain K06929 - - 0.00000000000000000000000000000004047 128.0
TH1_k127_1060172_2 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 560.0
TH1_k127_1060172_20 uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center K05297 - 1.18.1.1 0.00000000000000000000000002658 108.0
TH1_k127_1060172_21 - - - - 0.0000000000000000000000004361 108.0
TH1_k127_1060172_22 Crp Fnr family K01420,K15861 - - 0.00000000000000001967 91.0
TH1_k127_1060172_23 Transposase K07483 - - 0.000000000002485 71.0
TH1_k127_1060172_24 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0005241 49.0
TH1_k127_1060172_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 534.0
TH1_k127_1060172_4 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 469.0
TH1_k127_1060172_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 424.0
TH1_k127_1060172_6 transmembrane signaling receptor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 397.0
TH1_k127_1060172_7 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 366.0
TH1_k127_1060172_8 PFAM regulatory protein, MerR K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 304.0
TH1_k127_1060172_9 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 292.0
TH1_k127_1077127_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1406.0
TH1_k127_1077127_1 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 510.0
TH1_k127_1077127_2 PFAM HTH transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 478.0
TH1_k127_1077127_3 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 298.0
TH1_k127_1077127_4 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000004715 141.0
TH1_k127_1097333_0 GAF domain - - - 1.212e-210 667.0
TH1_k127_1097333_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 575.0
TH1_k127_1097333_2 Lysin motif K08307 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 538.0
TH1_k127_1097333_3 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 358.0
TH1_k127_1097333_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000006658 239.0
TH1_k127_1133872_0 threonine synthase K01733 - 4.2.3.1 3.767e-245 764.0
TH1_k127_1133872_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 456.0
TH1_k127_1133872_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 299.0
TH1_k127_1133872_3 Response regulator receiver K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001331 259.0
TH1_k127_1133872_4 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000002606 185.0
TH1_k127_1143568_0 ABC transporter - - - 9.229e-305 940.0
TH1_k127_1143568_1 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 607.0
TH1_k127_1143568_2 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 377.0
TH1_k127_1143568_3 guanyl-nucleotide exchange factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 368.0
TH1_k127_1143568_4 Bacterial Ig-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 344.0
TH1_k127_1143568_6 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0003061 43.0
TH1_k127_1241420_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 5.742e-289 895.0
TH1_k127_1241420_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000008089 191.0
TH1_k127_1241420_2 Psort location Cytoplasmic, score 8.96 K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000006683 154.0
TH1_k127_1250034_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.868e-239 754.0
TH1_k127_1250034_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 370.0
TH1_k127_1250034_2 Permease MlaE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001412 271.0
TH1_k127_1250034_3 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000002909 169.0
TH1_k127_1250034_4 Anti-sigma-factor antagonist K04749 - - 0.00000000000000000000000000000008746 127.0
TH1_k127_1250034_5 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000001089 115.0
TH1_k127_1250034_7 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000001776 65.0
TH1_k127_1255575_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.109e-236 743.0
TH1_k127_1255575_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 6.196e-212 665.0
TH1_k127_1255575_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 406.0
TH1_k127_1255575_3 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 281.0
TH1_k127_1255575_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000004762 224.0
TH1_k127_1255575_5 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000001739 173.0
TH1_k127_1255575_6 Sterol-binding domain protein K03690 - - 0.00000000000000000000000000000000000000000000003412 176.0
TH1_k127_1255575_7 Protein of unknown function (DUF2846) - - - 0.00006128 52.0
TH1_k127_1299657_0 Alpha-2-Macroglobulin K06894 - - 0.0 1834.0
TH1_k127_1299657_1 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 0.0 1086.0
TH1_k127_1299657_10 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 351.0
TH1_k127_1299657_11 (ABC) transporter K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 335.0
TH1_k127_1299657_12 PFAM ATP-binding region ATPase domain protein K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 327.0
TH1_k127_1299657_13 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 298.0
TH1_k127_1299657_14 NosL family K19342 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003467 241.0
TH1_k127_1299657_15 PFAM response regulator receiver K15012 - - 0.000000000000000000000000000000000000000000000000000000000000000001386 231.0
TH1_k127_1299657_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000003598 216.0
TH1_k127_1299657_17 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000000000000000004674 213.0
TH1_k127_1299657_18 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000005555 159.0
TH1_k127_1299657_19 Sulfurtransferase - - - 0.000000000000000000000000000000000000000001549 160.0
TH1_k127_1299657_2 FMN-binding domain protein K19339 - - 0.0 1030.0
TH1_k127_1299657_20 Thioredoxin domain - - - 0.00000000000000000000000000000001044 129.0
TH1_k127_1299657_21 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000022 114.0
TH1_k127_1299657_22 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039 - - 0.00000000000000000000001799 103.0
TH1_k127_1299657_23 NosL family K19342 - - 0.00000000000005093 75.0
TH1_k127_1299657_26 NosL family K19342 - - 0.0000001453 53.0
TH1_k127_1299657_3 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 2.955e-277 873.0
TH1_k127_1299657_4 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 9.11e-226 717.0
TH1_k127_1299657_5 Periplasmic copper-binding K07218 - - 6.424e-206 647.0
TH1_k127_1299657_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 558.0
TH1_k127_1299657_7 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 503.0
TH1_k127_1299657_8 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 505.0
TH1_k127_1299657_9 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992,K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 411.0
TH1_k127_1309615_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 1.923e-272 848.0
TH1_k127_1309615_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 2.648e-212 665.0
TH1_k127_1309615_10 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000000001758 187.0
TH1_k127_1309615_11 TraB family K09973 - - 0.00000000000000000000000000000000000000000001188 174.0
TH1_k127_1309615_12 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000001179 143.0
TH1_k127_1309615_13 COG1278 Cold shock proteins K03704 - - 0.000000000000000000000000000000739 126.0
TH1_k127_1309615_14 COG1278 Cold shock proteins K03704 - - 0.000000000000000000000000001068 113.0
TH1_k127_1309615_15 YcgL domain K09902 - - 0.0000000000000000002253 91.0
TH1_k127_1309615_16 - - - - 0.0000000001096 69.0
TH1_k127_1309615_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 4.356e-196 620.0
TH1_k127_1309615_3 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 481.0
TH1_k127_1309615_4 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 383.0
TH1_k127_1309615_5 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 348.0
TH1_k127_1309615_6 Aminotransferase, class I K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 323.0
TH1_k127_1309615_7 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007831 271.0
TH1_k127_1309615_8 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 255.0
TH1_k127_1309615_9 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000122 215.0
TH1_k127_1316166_0 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 1.564e-228 713.0
TH1_k127_1316166_1 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 540.0
TH1_k127_1316166_10 short-chain dehydrogenase reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 296.0
TH1_k127_1316166_11 Squalene/phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 290.0
TH1_k127_1316166_12 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003327 278.0
TH1_k127_1316166_13 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005028 252.0
TH1_k127_1316166_14 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004418 242.0
TH1_k127_1316166_15 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000000007842 214.0
TH1_k127_1316166_16 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000009183 211.0
TH1_k127_1316166_17 lactoylglutathione lyase activity K08234 - - 0.000000000000000000000000000000000000000000000002737 175.0
TH1_k127_1316166_18 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000003264 181.0
TH1_k127_1316166_19 Belongs to the ArsC family - - - 0.000000000000000000000000000000000000000003218 157.0
TH1_k127_1316166_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 461.0
TH1_k127_1316166_20 PFAM YCII-related K09780 - - 0.00000000000000000000000000000000000000004076 155.0
TH1_k127_1316166_21 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000005674 159.0
TH1_k127_1316166_22 SprA-related family - - - 0.000000000000000000000000000001588 128.0
TH1_k127_1316166_23 PilZ domain - - - 0.0000000000000002907 82.0
TH1_k127_1316166_24 Flagellar motor protein K02557 - - 0.000000002744 61.0
TH1_k127_1316166_26 Protein of unknown function (DUF2802) - - - 0.0000001379 58.0
TH1_k127_1316166_27 - - - - 0.0000009622 53.0
TH1_k127_1316166_3 Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 406.0
TH1_k127_1316166_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 365.0
TH1_k127_1316166_5 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 355.0
TH1_k127_1316166_6 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 340.0
TH1_k127_1316166_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 331.0
TH1_k127_1316166_8 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 308.0
TH1_k127_1316166_9 Belongs to the SUA5 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 299.0
TH1_k127_1316491_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 4.56e-293 908.0
TH1_k127_1316491_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 591.0
TH1_k127_1316491_2 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000098 250.0
TH1_k127_1316491_3 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000005871 231.0
TH1_k127_1317604_0 ABC transporter transmembrane region K12541 - - 1.067e-247 784.0
TH1_k127_1317604_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 2.575e-199 630.0
TH1_k127_1317604_10 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000001048 124.0
TH1_k127_1317604_11 - - - - 0.0000000000000005364 80.0
TH1_k127_1317604_12 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000817 54.0
TH1_k127_1317604_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 497.0
TH1_k127_1317604_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 463.0
TH1_k127_1317604_4 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 424.0
TH1_k127_1317604_5 TIGRFAM type I secretion membrane fusion protein, HlyD family K12542 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 422.0
TH1_k127_1317604_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 294.0
TH1_k127_1317604_7 NADP transhydrogenase K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000004174 171.0
TH1_k127_1317604_8 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000007826 152.0
TH1_k127_1317604_9 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000003738 132.0
TH1_k127_1321310_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 378.0
TH1_k127_1321310_1 PFAM Uncharacterised protein family UPF0066 - GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005318 258.0
TH1_k127_1321310_2 2OG-Fe(II) oxygenase K07394 - - 0.000000000000000000000000000000000005819 138.0
TH1_k127_1321310_3 Methyltransferase domain - - - 0.00000000000000004151 90.0
TH1_k127_1338089_0 Phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 459.0
TH1_k127_1338089_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 407.0
TH1_k127_1338089_2 PFAM CBS domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 325.0
TH1_k127_1338089_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000001856 183.0
TH1_k127_1338089_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000004552 178.0
TH1_k127_1380307_0 Belongs to the aldehyde dehydrogenase family K13821 - 1.2.1.88,1.5.5.2 1.161e-283 902.0
TH1_k127_1380307_1 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 1.539e-212 683.0
TH1_k127_1380307_10 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000003171 138.0
TH1_k127_1380307_11 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000007635 94.0
TH1_k127_1380307_12 - - - - 0.000000000000000000004075 102.0
TH1_k127_1380307_13 PFAM Type IV pilus assembly PilZ - - - 0.0000000000000002545 83.0
TH1_k127_1380307_14 - - - - 0.0000000000000002567 80.0
TH1_k127_1380307_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000994 376.0
TH1_k127_1380307_3 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 363.0
TH1_k127_1380307_4 PFAM ABC-type uncharacterised transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 364.0
TH1_k127_1380307_5 Diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 310.0
TH1_k127_1380307_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007967 259.0
TH1_k127_1380307_7 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000001034 187.0
TH1_k127_1380307_8 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000001162 179.0
TH1_k127_1380307_9 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000001414 149.0
TH1_k127_1394042_0 Diguanylate cyclase - - - 0.0 1046.0
TH1_k127_1394042_1 Diguanylate cyclase - - - 8.08e-269 857.0
TH1_k127_1394042_10 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001339 271.0
TH1_k127_1394042_11 NMT1-like family K02051,K15553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001752 259.0
TH1_k127_1394042_12 Histidine Phosphotransfer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001167 249.0
TH1_k127_1394042_14 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000008797 209.0
TH1_k127_1394042_15 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000002564 229.0
TH1_k127_1394042_16 E-Z type HEAT repeats - - - 0.000000000000000000000000000000000000000000001507 179.0
TH1_k127_1394042_17 - - - - 0.00000000000000000000000000000000000000004277 155.0
TH1_k127_1394042_18 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000001576 147.0
TH1_k127_1394042_19 - - - - 0.000000000000000000000000000000000893 145.0
TH1_k127_1394042_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 569.0
TH1_k127_1394042_20 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000001031 90.0
TH1_k127_1394042_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 537.0
TH1_k127_1394042_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 484.0
TH1_k127_1394042_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 491.0
TH1_k127_1394042_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 465.0
TH1_k127_1394042_7 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 443.0
TH1_k127_1394042_8 Methyl-transferase K06983 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 413.0
TH1_k127_1413331_0 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 409.0
TH1_k127_1413331_1 PFAM Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 358.0
TH1_k127_1413331_10 small membrane protein - - - 0.000000000000000000000000000000002577 132.0
TH1_k127_1413331_11 Domain of unknown function (DUF4136) - - - 0.00000000000000001805 89.0
TH1_k127_1413331_12 Belongs to the BolA IbaG family - - - 0.0000000000000003571 81.0
TH1_k127_1413331_13 Protein of unknown function (DUF2835) - - - 0.0000000000000006346 79.0
TH1_k127_1413331_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily K06968 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.186 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 352.0
TH1_k127_1413331_3 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 337.0
TH1_k127_1413331_4 Putative manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000107 284.0
TH1_k127_1413331_5 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001551 275.0
TH1_k127_1413331_6 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000932 237.0
TH1_k127_1413331_7 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000001686 243.0
TH1_k127_1413331_8 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.0000000000000000000000000000000000000000000000000000000000000000001571 239.0
TH1_k127_1413331_9 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000002936 195.0
TH1_k127_1425022_0 TIGRFAM ATP-dependent DNA helicase, RecQ K03654 - 3.6.4.12 6.551e-261 816.0
TH1_k127_1425022_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000001424 197.0
TH1_k127_1425022_2 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000006327 51.0
TH1_k127_1434112_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 518.0
TH1_k127_1434112_1 High frequency lysogenization protein HflD homolog K07153 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009898,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:0098562 - 0.000000000000000000000000000000000000000000000000005347 189.0
TH1_k127_1434112_2 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000002117 179.0
TH1_k127_1434112_3 membrane protein TerC - - - 0.0000000533 54.0
TH1_k127_1456466_0 Chromate transporter K07240 - - 1.053e-229 718.0
TH1_k127_1456466_1 His Kinase A (phosphoacceptor) domain - - - 1.473e-203 677.0
TH1_k127_1456466_10 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 318.0
TH1_k127_1456466_11 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009379 270.0
TH1_k127_1456466_12 PFAM ATP-binding region ATPase domain protein, ABC transporter substrate binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002877 278.0
TH1_k127_1456466_13 - - - - 0.00000000000000000000000000000000004953 140.0
TH1_k127_1456466_14 Rhodanese domain protein - - - 0.00000000000000000000000000004869 119.0
TH1_k127_1456466_15 STAS domain K20978 - - 0.00000000000000000008588 92.0
TH1_k127_1456466_16 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00002068 48.0
TH1_k127_1456466_2 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 1.321e-199 638.0
TH1_k127_1456466_3 Glycosyltransferase Family 4 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 484.0
TH1_k127_1456466_4 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 484.0
TH1_k127_1456466_5 response regulator receiver K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 417.0
TH1_k127_1456466_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 407.0
TH1_k127_1456466_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 417.0
TH1_k127_1456466_8 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 363.0
TH1_k127_1456466_9 COG0784 FOG CheY-like receiver K20977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 325.0
TH1_k127_1459033_0 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 370.0
TH1_k127_1459033_1 GTP-binding GTPase Middle Region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 351.0
TH1_k127_1459033_2 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 338.0
TH1_k127_1459033_3 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001463 247.0
TH1_k127_1459033_4 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000004838 203.0
TH1_k127_1459033_5 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000003648 182.0
TH1_k127_1459033_6 - - - - 0.00000000000000000000000000000000000005101 145.0
TH1_k127_1474220_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 440.0
TH1_k127_1474220_1 signal transduction histidine kinase K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 408.0
TH1_k127_1474220_2 Domain of unknown function (DUF4124) - - - 0.00000001343 60.0
TH1_k127_1501273_0 argininosuccinate lyase K01755 - 4.3.2.1 2.646e-232 726.0
TH1_k127_1501273_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 424.0
TH1_k127_1501273_10 response regulator receiver - - - 0.000000000002791 74.0
TH1_k127_1501273_2 Response regulator of the LytR AlgR family K08083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001423 278.0
TH1_k127_1501273_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002319 281.0
TH1_k127_1501273_4 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000691 256.0
TH1_k127_1501273_5 phospholipase Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000005383 235.0
TH1_k127_1501273_6 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000002383 173.0
TH1_k127_1501273_7 - - - - 0.00000000000000000000000000002054 121.0
TH1_k127_1501273_8 - - - - 0.0000000000000000000000002948 110.0
TH1_k127_1501273_9 - - - - 0.000000000000000007267 89.0
TH1_k127_1538109_0 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002244 296.0
TH1_k127_1538109_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000006245 184.0
TH1_k127_1538109_2 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.00000000000000000000000000002275 121.0
TH1_k127_1541276_0 TIGRFAM ribonuclease, Rne Rng family K08301 - - 4.155e-212 668.0
TH1_k127_1541276_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 609.0
TH1_k127_1541276_10 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000006641 149.0
TH1_k127_1541276_14 Protein of unknown function (DUF1631) - - - 0.0007619 44.0
TH1_k127_1541276_2 PFAM Glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 438.0
TH1_k127_1541276_3 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 440.0
TH1_k127_1541276_4 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 363.0
TH1_k127_1541276_5 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 299.0
TH1_k127_1541276_6 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000005257 219.0
TH1_k127_1541276_7 maF-like protein K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - 0.00000000000000000000000000000000000000000000000000000000000606 215.0
TH1_k127_1541276_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000001265 207.0
TH1_k127_1541276_9 Peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000001926 190.0
TH1_k127_1568549_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 0.0 1750.0
TH1_k127_1568549_1 5'-nucleotidase, C-terminal domain K17224 - - 1.228e-284 884.0
TH1_k127_1568549_2 AcrB/AcrD/AcrF family K18138 - - 5.171e-266 822.0
TH1_k127_1568549_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 417.0
TH1_k127_1568549_4 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000000000000008482 195.0
TH1_k127_1590822_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001714 281.0
TH1_k127_1590822_1 Ceramidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003095 247.0
TH1_k127_1590822_2 transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000007284 239.0
TH1_k127_1590822_3 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000004194 123.0
TH1_k127_1590822_4 OmpA-like transmembrane domain - - - 0.00001179 55.0
TH1_k127_159231_0 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 528.0
TH1_k127_159231_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 319.0
TH1_k127_159231_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004013 281.0
TH1_k127_159231_3 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000007431 188.0
TH1_k127_159231_4 Protein of unknown function (DUF3025) - - - 0.0000000000000000000000000000000000000000005815 162.0
TH1_k127_159231_5 Cytochrome c - - - 0.0000000001016 66.0
TH1_k127_1607539_0 PFAM von Willebrand factor type A K02448 - - 6.788e-198 638.0
TH1_k127_1607539_1 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 451.0
TH1_k127_1607539_2 phosphate-selective porin O and P - - - 0.000000000000006999 78.0
TH1_k127_1607539_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily K06968 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.186 0.00004098 46.0
TH1_k127_1624504_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004044 270.0
TH1_k127_1624504_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001175 240.0
TH1_k127_1624504_2 - - - - 0.00000000000000000000000000000000000000000000000000000007475 200.0
TH1_k127_1624504_3 Bacterial SH3 domain homologues K07184 - - 0.00000000000000000000000000000007656 133.0
TH1_k127_1624504_4 membrane - - - 0.0000000000000000000005473 96.0
TH1_k127_1624504_5 SnoaL-like domain - - - 0.00000000000000000008286 94.0
TH1_k127_1627562_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.033e-195 616.0
TH1_k127_1627562_1 Aminopeptidase I zinc metalloprotease (M18) K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 571.0
TH1_k127_1627562_10 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000004285 216.0
TH1_k127_1627562_11 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000001389 204.0
TH1_k127_1627562_12 subfamily IA, variant 1 K20862 - 3.1.3.102,3.1.3.104 0.00000000000000000000000000000000000000000000000000002389 196.0
TH1_k127_1627562_13 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000002426 174.0
TH1_k127_1627562_14 - - - - 0.0000000001486 65.0
TH1_k127_1627562_15 n-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0004279 51.0
TH1_k127_1627562_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 536.0
TH1_k127_1627562_3 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 526.0
TH1_k127_1627562_4 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 497.0
TH1_k127_1627562_5 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 459.0
TH1_k127_1627562_6 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 418.0
TH1_k127_1627562_7 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 314.0
TH1_k127_1627562_8 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 300.0
TH1_k127_1627562_9 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001337 236.0
TH1_k127_1632486_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.87e-309 964.0
TH1_k127_1632486_1 Belongs to the peptidase S16 family - - - 8.01e-257 814.0
TH1_k127_1632486_10 response to stress - - - 0.000000000000000000002367 103.0
TH1_k127_1632486_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 3.741e-226 708.0
TH1_k127_1632486_3 PFAM ATP-grasp fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 553.0
TH1_k127_1632486_4 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 466.0
TH1_k127_1632486_5 PFAM Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 394.0
TH1_k127_1632486_6 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000136 262.0
TH1_k127_1632486_7 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000001783 196.0
TH1_k127_1632486_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000001904 176.0
TH1_k127_1632486_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000005904 163.0
TH1_k127_1661677_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.128e-270 852.0
TH1_k127_1661677_1 Transport of potassium into the cell K03549 - - 2.609e-251 790.0
TH1_k127_1661677_2 Cation transporter/ATPase, N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 548.0
TH1_k127_169307_0 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 411.0
TH1_k127_169307_1 Aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004594 276.0
TH1_k127_169307_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272,K21344 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008219,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0012501,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016779,GO:0019200,GO:0033692,GO:0033785,GO:0033786,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0070566,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000004466 234.0
TH1_k127_169307_3 TIGRFAM Lipopolysaccharide heptosyltransferase II K02843 - - 0.00000000000000000000000000000000000000000000000000000000004568 210.0
TH1_k127_1695668_0 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 356.0
TH1_k127_1695668_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 341.0
TH1_k127_1695668_2 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006985 253.0
TH1_k127_1695668_3 COG3038 Cytochrome B561 K12262 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000007694 239.0
TH1_k127_1695668_4 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000001522 203.0
TH1_k127_1742197_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1695.0
TH1_k127_1742197_1 ATP-dependent helicase K03578 K03578 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 575.0
TH1_k127_1742197_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 458.0
TH1_k127_1742197_3 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 433.0
TH1_k127_1742197_4 PFAM MazG nucleotide pyrophosphohydrolase K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 296.0
TH1_k127_1742197_5 Protein of unknown function (DUF3565) - - - 0.0000000000000000000000000000007812 123.0
TH1_k127_1742197_8 Type II secretory pathway, component ExeA K02450 - - 0.0000000000000001414 79.0
TH1_k127_179656_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4e-323 998.0
TH1_k127_179656_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 599.0
TH1_k127_179656_10 Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 308.0
TH1_k127_179656_11 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005053 274.0
TH1_k127_179656_12 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006995 261.0
TH1_k127_179656_13 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000004188 218.0
TH1_k127_179656_14 tRNA (guanine-N7-)-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000002031 192.0
TH1_k127_179656_15 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000006581 188.0
TH1_k127_179656_16 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000681 172.0
TH1_k127_179656_18 cytochrome c5 K02277 - 1.9.3.1 0.00000000000000000000000007473 112.0
TH1_k127_179656_19 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000001892 114.0
TH1_k127_179656_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 460.0
TH1_k127_179656_20 rho-dependent transcription termination K19000 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000002617 53.0
TH1_k127_179656_21 PEP-CTERM motif - - - 0.00003115 53.0
TH1_k127_179656_23 flagellar protein FliS K02422 - - 0.0001951 44.0
TH1_k127_179656_3 Sigma-54 interaction domain K10941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008804 442.0
TH1_k127_179656_4 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 411.0
TH1_k127_179656_5 PFAM Endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 376.0
TH1_k127_179656_6 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 374.0
TH1_k127_179656_7 ADP-glyceromanno-heptose 6-epimerase activity K00091,K01710 - 1.1.1.219,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 368.0
TH1_k127_179656_8 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 336.0
TH1_k127_179656_9 Domain of unknown function (DUF4202) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 295.0
TH1_k127_1797520_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 6.109e-225 702.0
TH1_k127_1797520_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 452.0
TH1_k127_1797520_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000001909 233.0
TH1_k127_1810643_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 454.0
TH1_k127_1810643_1 Phosphoserine phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 286.0
TH1_k127_1810643_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002051 248.0
TH1_k127_1810643_3 PFAM Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000000000000000006178 215.0
TH1_k127_1814731_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 6.54e-271 842.0
TH1_k127_1814731_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 561.0
TH1_k127_1814731_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000004248 208.0
TH1_k127_1814731_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000002482 129.0
TH1_k127_1814731_4 Regulatory protein recX K03565 GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - 0.0000000000000000000000004039 110.0
TH1_k127_1814731_5 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000002483 98.0
TH1_k127_1863800_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1467.0
TH1_k127_1863800_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 8.777e-211 662.0
TH1_k127_1863800_10 Forms part of the polypeptide exit tunnel K02926 GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000006259 248.0
TH1_k127_1863800_11 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000363 241.0
TH1_k127_1863800_12 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000007458 238.0
TH1_k127_1863800_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000002565 230.0
TH1_k127_1863800_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000005406 223.0
TH1_k127_1863800_15 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000001488 221.0
TH1_k127_1863800_16 Ribosomal protein L17 K02879 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002313 196.0
TH1_k127_1863800_17 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002636 192.0
TH1_k127_1863800_18 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000003205 187.0
TH1_k127_1863800_19 Involved in the binding of tRNA to the ribosomes K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000007056 184.0
TH1_k127_1863800_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 480.0
TH1_k127_1863800_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 - 0.000000000000000000000000000000000000000000000000001681 184.0
TH1_k127_1863800_21 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000002313 166.0
TH1_k127_1863800_22 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000005372 166.0
TH1_k127_1863800_23 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000001344 162.0
TH1_k127_1863800_24 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000206 158.0
TH1_k127_1863800_25 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000003189 133.0
TH1_k127_1863800_26 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000005465 132.0
TH1_k127_1863800_27 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000001668 128.0
TH1_k127_1863800_28 Ribosomal protein L30 K02907 - - 0.00000000000000000000002295 100.0
TH1_k127_1863800_29 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000004331 72.0
TH1_k127_1863800_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 459.0
TH1_k127_1863800_30 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000003986 68.0
TH1_k127_1863800_31 structural constituent of ribosome K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000945 70.0
TH1_k127_1863800_4 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 451.0
TH1_k127_1863800_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 351.0
TH1_k127_1863800_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 322.0
TH1_k127_1863800_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 300.0
TH1_k127_1863800_8 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 301.0
TH1_k127_1863800_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001371 251.0
TH1_k127_1900833_0 Integral membrane protein TerC family K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 479.0
TH1_k127_1900833_1 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 322.0
TH1_k127_1900833_10 Cysteine-rich CWC - - - 0.00000000000000000001659 93.0
TH1_k127_1900833_12 Histidine kinase-like ATPases - - - 0.000000000000006053 81.0
TH1_k127_1900833_13 - - - - 0.0000000000001632 70.0
TH1_k127_1900833_2 Protein of unknown function (DUF1456) - - - 0.000000000000000000000000000000000000000000000000000000000000000006998 228.0
TH1_k127_1900833_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000001351 196.0
TH1_k127_1900833_4 - - - - 0.0000000000000000000000000000000000000000000000000007399 189.0
TH1_k127_1900833_5 transport - - - 0.00000000000000000000000000000000000000000001375 171.0
TH1_k127_1900833_6 Phosphate-starvation-inducible E K13256 - - 0.000000000000000000000000000000000000000004072 158.0
TH1_k127_1900833_7 relative of glutathione S-transferase, MAPEG superfamily K07136 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000004436 149.0
TH1_k127_1900833_8 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.00000000000000000000000000000000000001715 146.0
TH1_k127_1900833_9 - - - - 0.00000000000000000000000000001799 123.0
TH1_k127_1914959_0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 583.0
TH1_k127_1914959_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 481.0
TH1_k127_1914959_2 Belongs to the flagella basal body rod proteins family K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 411.0
TH1_k127_1914959_3 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 301.0
TH1_k127_1914959_4 Flagellar rod assembly protein muramidase FlgJ K02395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001874 261.0
TH1_k127_1914959_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000006071 223.0
TH1_k127_1914959_6 Flagellar hook-associated protein 3 K02397 - - 0.000000000000000000000000000000000000000000000000000000000000009629 239.0
TH1_k127_1914959_7 PFAM Amino acid-binding ACT K03567 - - 0.0000000000000000000000000000000000000000000001207 173.0
TH1_k127_1914959_8 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000005607 141.0
TH1_k127_193462_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 1.519e-251 785.0
TH1_k127_193462_1 DNA Recombination protein RmuC K09760 GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 487.0
TH1_k127_193462_10 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000001822 119.0
TH1_k127_193462_11 - - - - 0.0000000000000000000000286 101.0
TH1_k127_193462_12 PilZ domain - - - 0.00002767 51.0
TH1_k127_193462_13 of the drug metabolite transporter (DMT) superfamily - - - 0.00007344 45.0
TH1_k127_193462_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 453.0
TH1_k127_193462_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 361.0
TH1_k127_193462_4 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 311.0
TH1_k127_193462_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000642 232.0
TH1_k127_193462_6 transcriptional regulator K09017 - - 0.000000000000000000000000000000000000000000000000001711 188.0
TH1_k127_193462_7 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 0.00000000000000000000000000000000000000001323 159.0
TH1_k127_193462_8 Belongs to the UPF0225 family K09858 - - 0.00000000000000000000000000000000001058 143.0
TH1_k127_193462_9 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.00000000000000000000000000000002434 130.0
TH1_k127_1947944_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 540.0
TH1_k127_1947944_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 438.0
TH1_k127_1947944_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000003056 60.0
TH1_k127_2037471_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 574.0
TH1_k127_2037471_1 Glycosyl transferase 4-like K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002715 289.0
TH1_k127_2037471_2 lipopolysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006311 257.0
TH1_k127_2037471_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000009686 230.0
TH1_k127_2037471_4 Purple acid Phosphatase, N-terminal domain - - - 0.0000000000000000003484 94.0
TH1_k127_2168420_0 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 304.0
TH1_k127_2168420_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000204 139.0
TH1_k127_2168420_2 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00002208 49.0
TH1_k127_219304_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1139.0
TH1_k127_219304_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 1.685e-242 766.0
TH1_k127_219304_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000001492 273.0
TH1_k127_219304_11 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002819 264.0
TH1_k127_219304_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008207 247.0
TH1_k127_219304_14 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis - - - 0.0002498 53.0
TH1_k127_219304_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.317e-229 721.0
TH1_k127_219304_3 Phosphoglycerate kinase K00927 - 2.7.2.3 1.5e-215 673.0
TH1_k127_219304_4 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 1.96e-208 650.0
TH1_k127_219304_5 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 8.568e-201 636.0
TH1_k127_219304_6 Bacterial protein of unknown function (DUF853) K06915 - - 1.702e-194 617.0
TH1_k127_219304_7 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 603.0
TH1_k127_219304_8 DEAD-box RNA helicase involved in K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009804 594.0
TH1_k127_219304_9 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 317.0
TH1_k127_2256478_0 DNA segregation ATPase FtsK SpoIIIE K03466 - - 1.199e-194 621.0
TH1_k127_2256478_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 516.0
TH1_k127_2256478_2 alanine dehydrogenase K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 425.0
TH1_k127_2256478_3 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001292 275.0
TH1_k127_2372889_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 8.137e-255 796.0
TH1_k127_2372889_1 - - - - 0.00000000000000000000000000000000000000000001351 171.0
TH1_k127_2428784_0 PrkA AAA domain K07180 - - 0.0 1111.0
TH1_k127_2428784_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 3.189e-275 876.0
TH1_k127_2428784_10 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0051087,GO:0071944 - 0.00000000000000000000000000000000000000000004137 170.0
TH1_k127_2428784_11 Zinc-finger domain - - - 0.00000000000000000000005135 99.0
TH1_k127_2428784_2 SpoVR like protein K06415 - - 2.094e-253 792.0
TH1_k127_2428784_3 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 609.0
TH1_k127_2428784_4 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 542.0
TH1_k127_2428784_5 Belongs to the UPF0229 family K09786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 539.0
TH1_k127_2428784_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 516.0
TH1_k127_2428784_7 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 485.0
TH1_k127_2428784_8 ApbE family K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000003417 249.0
TH1_k127_2428784_9 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000002199 213.0
TH1_k127_2464507_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1217.0
TH1_k127_2464507_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 5.61e-309 954.0
TH1_k127_2464507_10 ATPase associated with various cellular activities AAA_5 K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 440.0
TH1_k127_2464507_11 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 431.0
TH1_k127_2464507_12 ADP-L-glycero-beta-D-manno-heptose biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 416.0
TH1_k127_2464507_13 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 418.0
TH1_k127_2464507_14 chemotaxis, protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 389.0
TH1_k127_2464507_15 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 354.0
TH1_k127_2464507_16 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 293.0
TH1_k127_2464507_17 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001036 267.0
TH1_k127_2464507_18 Catalyzes the synthesis of activated sulfate K00860 GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000003004 261.0
TH1_k127_2464507_19 Cytochrome c K02305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003819 246.0
TH1_k127_2464507_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.667e-270 846.0
TH1_k127_2464507_20 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0033739,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000158 225.0
TH1_k127_2464507_21 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000001422 200.0
TH1_k127_2464507_22 PFAM Response regulator receiver domain K07689 - - 0.000000000000000000000000000000000000000000000000002432 189.0
TH1_k127_2464507_23 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000002417 190.0
TH1_k127_2464507_24 Response regulator receiver K02658 - - 0.0000000000000000000000000000000000000000000002295 170.0
TH1_k127_2464507_25 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000001081 146.0
TH1_k127_2464507_26 Pfam Hemerythrin HHE - - - 0.000000000000000000000000000000000004191 142.0
TH1_k127_2464507_27 Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000000000000000000001357 142.0
TH1_k127_2464507_28 Membrane - - - 0.000000000000000000000000000001792 124.0
TH1_k127_2464507_29 - - - - 0.000000000000000000000000000007449 123.0
TH1_k127_2464507_3 Cytochrome C and Quinol oxidase polypeptide I K04561 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0055114 1.7.2.5 4.873e-254 788.0
TH1_k127_2464507_30 CheW-like domain - - - 0.00000000000000000000000003856 114.0
TH1_k127_2464507_31 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.0000000000000000000000001206 108.0
TH1_k127_2464507_32 Acyltransferase family - - - 0.000000000000000000007794 106.0
TH1_k127_2464507_33 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.00000000000000004404 91.0
TH1_k127_2464507_34 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000006908 85.0
TH1_k127_2464507_35 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000614 72.0
TH1_k127_2464507_36 SlyX K03745 - - 0.0000004119 54.0
TH1_k127_2464507_4 von Willebrand factor (vWF) type A domain K02448 - - 5.391e-206 658.0
TH1_k127_2464507_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 3.261e-205 656.0
TH1_k127_2464507_6 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 1.986e-199 639.0
TH1_k127_2464507_7 response regulator receiver - - - 7.382e-194 647.0
TH1_k127_2464507_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 520.0
TH1_k127_2464507_9 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 477.0
TH1_k127_2473796_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.712e-201 628.0
TH1_k127_2473796_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 522.0
TH1_k127_2473796_2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004208 258.0
TH1_k127_2473796_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000001407 177.0
TH1_k127_2496478_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.2e-319 1010.0
TH1_k127_2496478_1 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000000000000000000000003814 173.0
TH1_k127_253215_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 595.0
TH1_k127_253215_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 453.0
TH1_k127_253215_2 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 374.0
TH1_k127_253215_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 317.0
TH1_k127_253215_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000008571 239.0
TH1_k127_253215_5 Histidine kinase - - - 0.00000000000000000000000000000000000001386 158.0
TH1_k127_253215_6 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000005495 108.0
TH1_k127_2534620_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 560.0
TH1_k127_2534620_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000008859 262.0
TH1_k127_2534620_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000161 235.0
TH1_k127_2534620_3 Belongs to the CarB family K01955 - 6.3.5.5 0.0000000000000000000000000000000000002313 142.0
TH1_k127_2534620_4 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - 0.000000000000000000000000342 108.0
TH1_k127_2545955_0 EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 361.0
TH1_k127_2545955_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 315.0
TH1_k127_2545955_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004487 285.0
TH1_k127_2545955_3 Signal transduction protein K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001433 257.0
TH1_k127_2545955_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000001555 239.0
TH1_k127_2545955_5 Signal transduction protein K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000001288 220.0
TH1_k127_2545955_6 Pfam:Cache_2 - - - 0.00000000000000000000000000000000000000000000000000002167 193.0
TH1_k127_2545955_7 aminomethyltransferase related to GcvT K06980 GO:0003674,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0019842,GO:0022607,GO:0031163,GO:0031406,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071840,GO:0072341,GO:0097159,GO:1901363 - 0.000000000000000003367 87.0
TH1_k127_2618880_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 9.063e-294 907.0
TH1_k127_2618880_1 Heat shock 70 kDa protein K04043 - - 1.616e-287 894.0
TH1_k127_2618880_2 Cytochrome c bacterial - - - 3.913e-214 674.0
TH1_k127_2618880_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 3.944e-207 651.0
TH1_k127_2618880_4 Diguanylate cyclase (GGDEF domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 466.0
TH1_k127_2618880_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 417.0
TH1_k127_2618880_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 285.0
TH1_k127_2618880_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000009487 193.0
TH1_k127_2618880_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000004768 133.0
TH1_k127_2618880_9 COG2826 Transposase and inactivated derivatives, IS30 family K07482 - - 0.000000000005379 65.0
TH1_k127_2619192_0 Type II/IV secretion system protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 518.0
TH1_k127_2619192_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000004229 237.0
TH1_k127_2619192_2 Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000000000000000000000000000146 181.0
TH1_k127_2619192_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000009122 154.0
TH1_k127_2619192_4 CDP-archaeol synthase K19664 - 2.7.7.67 0.0000000000000000000000000000000000002308 146.0
TH1_k127_264074_0 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 503.0
TH1_k127_264074_1 Sulfate permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 429.0
TH1_k127_264074_2 COG0084 Mg-dependent DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 318.0
TH1_k127_264074_3 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000004985 223.0
TH1_k127_264074_4 PilZ domain K02676 - - 0.00000000000000000000000000000000000000000000000000259 183.0
TH1_k127_264074_5 - - - - 0.00000000000000000000000000000000000000000697 166.0
TH1_k127_264074_6 - - - - 0.00000000000000000000000000005341 123.0
TH1_k127_2644114_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1004.0
TH1_k127_2644114_1 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 542.0
TH1_k127_2644114_2 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 504.0
TH1_k127_2644114_3 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 472.0
TH1_k127_2644114_4 Transcriptional regulator K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 363.0
TH1_k127_2644114_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 308.0
TH1_k127_2644114_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001414 287.0
TH1_k127_2675548_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 460.0
TH1_k127_2675548_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772,K19696 - 2.4.2.28,2.4.2.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 338.0
TH1_k127_2675548_10 Protein of unknown function (DUF489) K07153 - - 0.0000000000000000001393 89.0
TH1_k127_2675548_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000006961 264.0
TH1_k127_2675548_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000005849 255.0
TH1_k127_2675548_4 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000002142 233.0
TH1_k127_2675548_5 Psort location Cytoplasmic, score 9.97 K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000001703 208.0
TH1_k127_2675548_6 esterase K07000 GO:0003674,GO:0003824,GO:0016787,GO:0016788 - 0.000000000000000000000000000000000000000000000000000005572 196.0
TH1_k127_2675548_7 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000157 145.0
TH1_k127_2675548_8 methyltransferase activity - - - 0.000000000000000000000000000001178 128.0
TH1_k127_2675548_9 protein kinase activity - - - 0.0000000000000000000000000459 116.0
TH1_k127_2678159_0 Belongs to the ClpA ClpB family K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1036.0
TH1_k127_2678159_1 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 7.136e-228 709.0
TH1_k127_2678159_10 Peptidoglycan-synthase activator LpoB K07337 - - 0.00000000000000000000000000000000000000000000000000000000000000000003796 237.0
TH1_k127_2678159_11 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006076 238.0
TH1_k127_2678159_12 PFAM Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002624 238.0
TH1_k127_2678159_13 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000001642 225.0
TH1_k127_2678159_14 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 - - 0.000000000000000000000000000000000000000000000000000007405 194.0
TH1_k127_2678159_15 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000001904 175.0
TH1_k127_2678159_16 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000000000003801 171.0
TH1_k127_2678159_17 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000006546 150.0
TH1_k127_2678159_18 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.00000000000000000000000000000000000001576 147.0
TH1_k127_2678159_19 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000001433 136.0
TH1_k127_2678159_2 Belongs to the citrate synthase family K01647 GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350 2.3.3.1 9.137e-215 674.0
TH1_k127_2678159_20 Invasion gene expression up-regulator SirB - - - 0.000000000000000000000000000000001381 134.0
TH1_k127_2678159_21 FOG TPR repeat, SEL1 subfamily K07126,K13582 - - 0.000000000001784 78.0
TH1_k127_2678159_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.456e-214 670.0
TH1_k127_2678159_4 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 608.0
TH1_k127_2678159_5 PFAM aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 526.0
TH1_k127_2678159_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 422.0
TH1_k127_2678159_7 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 373.0
TH1_k127_2678159_8 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 355.0
TH1_k127_2678159_9 protein conserved in bacteria K09859 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002984 289.0
TH1_k127_2678657_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 8.804e-233 734.0
TH1_k127_2678657_1 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016740,GO:0016741,GO:0016765,GO:0022607,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 411.0
TH1_k127_2678657_2 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 287.0
TH1_k127_2678657_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000002279 169.0
TH1_k127_2678657_4 Thioesterase superfamily protein K10806 - - 0.000000000000000000000000000000000000000879 151.0
TH1_k127_2678657_5 - - - - 0.0000000000000000000000000000000001271 139.0
TH1_k127_2678657_6 glyoxalase III activity - - - 0.00000000000000000000131 102.0
TH1_k127_2706317_0 AIR synthase related protein, N-terminal domain K04655 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0018193,GO:0018198,GO:0018249,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046892,GO:0051604,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 549.0
TH1_k127_2706317_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 524.0
TH1_k127_2706317_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 403.0
TH1_k127_2706317_3 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 318.0
TH1_k127_2706317_4 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000005866 222.0
TH1_k127_2720988_0 OmpA family - - - 0.0 1998.0
TH1_k127_2720988_1 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000251 207.0
TH1_k127_2720988_2 heavy metal transport detoxification protein K07213 - - 0.00000000000108 71.0
TH1_k127_2720988_3 UBA THIF-type NAD FAD binding K22132 - - 0.0001086 45.0
TH1_k127_2745292_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 2.295e-232 731.0
TH1_k127_2745292_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 503.0
TH1_k127_2745292_2 PFAM Cold-shock protein, DNA-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004074 253.0
TH1_k127_2745292_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000003852 198.0
TH1_k127_2745292_4 type III effector - - - 0.00000000000000000000000000000000000000000000137 167.0
TH1_k127_2745292_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000001184 103.0
TH1_k127_2827736_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 488.0
TH1_k127_2827736_1 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 426.0
TH1_k127_2827736_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 333.0
TH1_k127_283639_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 2.487e-219 690.0
TH1_k127_283639_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 561.0
TH1_k127_283639_2 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002908 265.0
TH1_k127_2845755_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 2.532e-217 679.0
TH1_k127_2845755_1 glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 547.0
TH1_k127_2845755_2 Endonuclease/Exonuclease/phosphatase family K01142 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008853,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 396.0
TH1_k127_2845755_3 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 338.0
TH1_k127_2845755_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009836 314.0
TH1_k127_2845755_5 TOBE domain K02052,K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000003132 235.0
TH1_k127_2858308_0 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 363.0
TH1_k127_2858308_1 With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P K04568 GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 325.0
TH1_k127_2858308_2 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 295.0
TH1_k127_2858308_3 lysine 2,3-aminomutase K19810 - - 0.000006058 51.0
TH1_k127_2899022_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.212e-272 844.0
TH1_k127_2899022_1 ATP synthase A chain K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 411.0
TH1_k127_2899022_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 394.0
TH1_k127_2899022_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 377.0
TH1_k127_2899022_4 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 337.0
TH1_k127_2899022_5 Chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000386 252.0
TH1_k127_2899022_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000001491 189.0
TH1_k127_2899022_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000002057 187.0
TH1_k127_2899022_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000003801 135.0
TH1_k127_2899022_9 ATP synthase I chain K02116 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00003955 51.0
TH1_k127_2946710_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1209.0
TH1_k127_2946710_1 TIGRFAM aminopeptidase N, Escherichia coli type K01256 - 3.4.11.2 1.33e-322 1008.0
TH1_k127_2946710_10 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 422.0
TH1_k127_2946710_11 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 415.0
TH1_k127_2946710_12 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 406.0
TH1_k127_2946710_13 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 359.0
TH1_k127_2946710_14 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 337.0
TH1_k127_2946710_15 ADP-glyceromanno-heptose 6-epimerase activity K00091,K01710 - 1.1.1.219,4.2.1.46 0.00000000000000000000000000000000000000000000000001366 193.0
TH1_k127_2946710_16 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000001965 128.0
TH1_k127_2946710_17 - - - - 0.000000000000000004561 87.0
TH1_k127_2946710_18 uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center K05297 - 1.18.1.1 0.000000000002409 68.0
TH1_k127_2946710_19 - - - - 0.00000000001504 66.0
TH1_k127_2946710_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 3.228e-224 700.0
TH1_k127_2946710_20 - - - - 0.00000006132 53.0
TH1_k127_2946710_21 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000002364 55.0
TH1_k127_2946710_3 transmembrane transport K02035,K13893 - - 1.584e-214 682.0
TH1_k127_2946710_4 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 587.0
TH1_k127_2946710_5 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 559.0
TH1_k127_2946710_6 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 543.0
TH1_k127_2946710_7 ABC transporter permease protein K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 495.0
TH1_k127_2946710_8 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 480.0
TH1_k127_2946710_9 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 484.0
TH1_k127_3046505_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 546.0
TH1_k127_3046505_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 500.0
TH1_k127_3046505_2 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000002238 195.0
TH1_k127_3054710_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.055e-313 992.0
TH1_k127_3054710_1 ABC transporter transmembrane region K06147 - - 2.438e-240 758.0
TH1_k127_3054710_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 294.0
TH1_k127_3054710_3 Specifically methylates the guanosine in position 1516 of 16S rRNA K15984 - 2.1.1.242 0.00000000000000000000000000000000000000000000000000000000000000001767 231.0
TH1_k127_3054710_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000008406 236.0
TH1_k127_3054710_5 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000000000000000000000000001032 146.0
TH1_k127_3063919_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1195.0
TH1_k127_3063919_1 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 604.0
TH1_k127_3063919_10 Pas domain - - - 0.00000000000000000000000000000000008776 156.0
TH1_k127_3063919_11 Bacterial Ig-like domain (group 1) - - - 0.0000000000454 72.0
TH1_k127_3063919_12 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000007278 55.0
TH1_k127_3063919_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 460.0
TH1_k127_3063919_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 419.0
TH1_k127_3063919_4 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 360.0
TH1_k127_3063919_5 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 345.0
TH1_k127_3063919_6 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003814 257.0
TH1_k127_3063919_7 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002381 252.0
TH1_k127_3063919_8 PFAM cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000003463 203.0
TH1_k127_3063919_9 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000001912 195.0
TH1_k127_3128193_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 5.158e-235 729.0
TH1_k127_3128193_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 308.0
TH1_k127_3128193_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000753 248.0
TH1_k127_3128193_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000001353 194.0
TH1_k127_3128193_4 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000000000000005837 135.0
TH1_k127_3151771_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005365 279.0
TH1_k127_3151771_1 Histidine Phosphotransfer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009227 260.0
TH1_k127_3151771_2 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000001797 208.0
TH1_k127_3151771_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000006071 209.0
TH1_k127_3151771_4 ABC transporter K06158 - - 0.0000228 50.0
TH1_k127_3219691_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 572.0
TH1_k127_3219691_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 485.0
TH1_k127_3219691_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 477.0
TH1_k127_3219691_3 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 337.0
TH1_k127_3219691_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 332.0
TH1_k127_3219691_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000005509 257.0
TH1_k127_3219691_7 Pfam Transposase IS66 - - - 0.000000000000000000000000003832 119.0
TH1_k127_3220270_0 NMT1-like family - - - 4.016e-199 627.0
TH1_k127_3220270_1 Bacterial protein of unknown function (DUF839) K07093 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 495.0
TH1_k127_3220270_2 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000567 221.0
TH1_k127_3220270_3 ANTAR K07183 - - 0.000000000000000000008876 100.0
TH1_k127_32527_0 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 8.742e-272 859.0
TH1_k127_32527_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000007948 203.0
TH1_k127_32527_2 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000002331 89.0
TH1_k127_32553_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0 1765.0
TH1_k127_32553_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 458.0
TH1_k127_32553_2 Protein of unknown function (DUF808) K09781 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 387.0
TH1_k127_32553_3 Transcriptional regulator K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 293.0
TH1_k127_32553_4 cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 290.0
TH1_k127_32553_6 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000002284 252.0
TH1_k127_32553_7 - - - - 0.0000000000000000000000000000000000000000000000000000001471 206.0
TH1_k127_32553_8 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000000000000000001853 134.0
TH1_k127_32553_9 - - - - 0.0000000000000000000000001421 118.0
TH1_k127_3294644_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1106.0
TH1_k127_3294644_1 Belongs to the CarA family K01956 GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 592.0
TH1_k127_3387292_0 Hydrogenase formation hypA family K04654 GO:0003674,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0036211,GO:0042165,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070025,GO:0071704,GO:1901564 - 2.849e-196 616.0
TH1_k127_3387292_1 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 435.0
TH1_k127_3387292_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 355.0
TH1_k127_3387292_3 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 334.0
TH1_k127_3387292_4 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000000000000003001 168.0
TH1_k127_3387292_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564 - 0.0000000000000000000000000000000000000000001982 162.0
TH1_k127_3387292_6 COG1309 Transcriptional regulator - - - 0.000000000000000000000000000000000000000007444 160.0
TH1_k127_3387292_7 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000000000000003389 126.0
TH1_k127_3415700_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 7.961e-287 896.0
TH1_k127_3415700_1 COG0643 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 3.224e-233 742.0
TH1_k127_3415700_10 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 309.0
TH1_k127_3415700_11 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 304.0
TH1_k127_3415700_12 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 296.0
TH1_k127_3415700_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 285.0
TH1_k127_3415700_14 Role in flagellar biosynthesis K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002905 280.0
TH1_k127_3415700_15 Histidine Phosphotransfer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000331 271.0
TH1_k127_3415700_16 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000011 228.0
TH1_k127_3415700_17 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.000000000000000000000000000000000000000000000000000000000000000267 228.0
TH1_k127_3415700_18 Flagellar motor protein K02557 - - 0.000000000000000000000000000000000000000000031 168.0
TH1_k127_3415700_19 DsrE/DsrF-like family K06039 - - 0.000000000000000000000000000000000000000005131 158.0
TH1_k127_3415700_2 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.541e-203 637.0
TH1_k127_3415700_20 Bacterial export proteins, family 3 K02420 - - 0.0000000000000000000000000103 113.0
TH1_k127_3415700_21 cystathionine gamma-synthase activity - - - 0.0000000000000000004001 102.0
TH1_k127_3415700_3 Major Facilitator Superfamily - - - 1.077e-201 641.0
TH1_k127_3415700_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 414.0
TH1_k127_3415700_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 395.0
TH1_k127_3415700_6 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 390.0
TH1_k127_3415700_7 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 366.0
TH1_k127_3415700_8 Bacterial regulatory protein, arsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 332.0
TH1_k127_3415700_9 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 339.0
TH1_k127_3492667_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 1.157e-250 786.0
TH1_k127_3632030_0 Signal recognition particle 54 kDa protein K03106 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016043,GO:0019904,GO:0022607,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0051259,GO:0051291,GO:0065003,GO:0070206,GO:0070208,GO:0071840 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 545.0
TH1_k127_3632030_1 cAMP phosphodiesterases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004066 284.0
TH1_k127_3632030_2 PFAM Cytochrome c assembly protein - - - 0.0000000005468 67.0
TH1_k127_3653244_0 Inorganic H+ pyrophosphatase K15987 - 3.6.1.1 0.0 1163.0
TH1_k127_3653244_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 8.586e-256 794.0
TH1_k127_3653244_2 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 452.0
TH1_k127_3653244_3 FecR protein - - - 0.000000000000000000000000000000000000000000000000000004716 218.0
TH1_k127_3653244_4 - - - - 0.000000000000000000000000000000000000000000004497 166.0
TH1_k127_3653244_5 - - - - 0.0000000000000001508 81.0
TH1_k127_3653244_6 Tetratricopeptide repeat - - - 0.0009344 46.0
TH1_k127_3657273_0 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 525.0
TH1_k127_3657273_1 belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 319.0
TH1_k127_3657273_2 PFAM Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000269 224.0
TH1_k127_3657273_3 metal cluster binding K06940 - - 0.000000000000000000000000000000000000000000000000000000000000002449 220.0
TH1_k127_3657273_4 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.000000000000000001604 92.0
TH1_k127_3657273_5 Protein of unknown function (DUF465) - - - 0.000000000000003716 78.0
TH1_k127_3657273_6 Type II secretion system (T2SS), protein N - - - 0.000000000000003787 85.0
TH1_k127_3657273_7 Hydrogenase maturation protease K03605 - - 0.000000000000004139 81.0
TH1_k127_3657273_8 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.000000000009293 74.0
TH1_k127_3714931_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 404.0
TH1_k127_3714931_1 Acetyl-coenzyme A transporter 1 K08218 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015835,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 374.0
TH1_k127_3714931_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 293.0
TH1_k127_3726078_0 PFAM TrkA-N domain K03499 - - 3.443e-196 622.0
TH1_k127_3726078_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 590.0
TH1_k127_3726078_10 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000325 151.0
TH1_k127_3726078_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 428.0
TH1_k127_3726078_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 398.0
TH1_k127_3726078_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 341.0
TH1_k127_3726078_5 PFAM Peptidoglycan-binding lysin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 299.0
TH1_k127_3726078_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000004457 260.0
TH1_k127_3726078_7 Bacterial lipid A biosynthesis acyltransferase K02560 - 2.3.1.243 0.0000000000000000000000000000000000000000000000000000000000000000000000697 250.0
TH1_k127_3726078_8 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000003284 241.0
TH1_k127_3726078_9 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000001079 178.0
TH1_k127_3768851_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1221.0
TH1_k127_3768851_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.251e-224 702.0
TH1_k127_3768851_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 461.0
TH1_k127_3768851_11 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 445.0
TH1_k127_3768851_12 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 434.0
TH1_k127_3768851_13 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 412.0
TH1_k127_3768851_14 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 399.0
TH1_k127_3768851_15 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 390.0
TH1_k127_3768851_16 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 376.0
TH1_k127_3768851_17 PFAM LppC K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 388.0
TH1_k127_3768851_18 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 370.0
TH1_k127_3768851_19 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 362.0
TH1_k127_3768851_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.298e-208 653.0
TH1_k127_3768851_20 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain K04691,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 334.0
TH1_k127_3768851_21 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 322.0
TH1_k127_3768851_22 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 318.0
TH1_k127_3768851_23 1-aminocyclopropane-1-carboxylate deaminase K01505 - 3.5.99.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 302.0
TH1_k127_3768851_24 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 297.0
TH1_k127_3768851_25 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 293.0
TH1_k127_3768851_26 metal-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002274 280.0
TH1_k127_3768851_27 Belongs to the WrbA family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004568 269.0
TH1_k127_3768851_28 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000943 267.0
TH1_k127_3768851_29 Stringent starvation protein A K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003761 263.0
TH1_k127_3768851_3 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 610.0
TH1_k127_3768851_30 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000005316 193.0
TH1_k127_3768851_31 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000002906 183.0
TH1_k127_3768851_32 COG1393 Arsenate reductase and related proteins, glutaredoxin family K00537 - 1.20.4.1 0.0000000000000000000000000000000000000000000001398 171.0
TH1_k127_3768851_33 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000003746 164.0
TH1_k127_3768851_34 Stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000000000005326 164.0
TH1_k127_3768851_35 LysM domain - - - 0.0000000000000000000000000005806 122.0
TH1_k127_3768851_36 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000001519 118.0
TH1_k127_3768851_37 Predicted membrane protein (DUF2069) - - - 0.0000000000000000000006325 100.0
TH1_k127_3768851_38 - - - - 0.0000000000000000001949 93.0
TH1_k127_3768851_39 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000002284 88.0
TH1_k127_3768851_4 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 613.0
TH1_k127_3768851_40 hemerythrin HHE cation binding domain - - - 0.00000000000004767 79.0
TH1_k127_3768851_41 - - - - 0.00000000006389 70.0
TH1_k127_3768851_42 Protein conserved in bacteria - - - 0.0000001379 59.0
TH1_k127_3768851_44 peptidyl-tyrosine sulfation - - - 0.000007705 56.0
TH1_k127_3768851_45 - - - - 0.00002978 52.0
TH1_k127_3768851_5 FAD linked oxidases, C-terminal domain K03777 - 1.1.5.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 606.0
TH1_k127_3768851_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 539.0
TH1_k127_3768851_7 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 494.0
TH1_k127_3768851_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 486.0
TH1_k127_3768851_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 485.0
TH1_k127_3770095_0 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000001128 160.0
TH1_k127_3770351_0 PFAM CoA-binding domain protein K09181 - - 0.0 1470.0
TH1_k127_3770351_1 Atp-dependent helicase K03579 - 3.6.4.13 9.471e-297 932.0
TH1_k127_3770351_10 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000001703 131.0
TH1_k127_3770351_11 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000000002356 125.0
TH1_k127_3770351_12 Cyclic nucleotide-binding - - - 0.00000000000000000000000006387 112.0
TH1_k127_3770351_13 Protein of unknown function (DUF3185) - - - 0.0000000000000000000758 90.0
TH1_k127_3770351_14 Cysteine-rich CPXCG - - - 0.0000000000000000002025 90.0
TH1_k127_3770351_2 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 1.338e-194 646.0
TH1_k127_3770351_3 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 474.0
TH1_k127_3770351_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 388.0
TH1_k127_3770351_5 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 367.0
TH1_k127_3770351_6 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000001736 230.0
TH1_k127_3770351_7 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000005522 224.0
TH1_k127_3770351_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000002103 214.0
TH1_k127_3770351_9 Small multidrug resistance protein K03297 - - 0.00000000000000000000000000000000000001547 146.0
TH1_k127_377114_0 Bifunctional transglycosylase second domain K05365 - 2.4.1.129,3.4.16.4 3.559e-233 743.0
TH1_k127_377114_1 Helicase K03722 - 3.6.4.12 2.094e-226 718.0
TH1_k127_377114_2 Tetratricopeptide repeat - - - 0.000000009875 63.0
TH1_k127_377114_3 Glycoprotease family K14742 - - 0.000001835 49.0
TH1_k127_3790324_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1020.0
TH1_k127_3790324_1 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005975 261.0
TH1_k127_3790324_2 LemA Family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001573 252.0
TH1_k127_3790324_3 TPM domain K08988 - - 0.0000000000000000000000000000000000000000000859 167.0
TH1_k127_3829653_0 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 344.0
TH1_k127_3829653_1 Diguanylate cyclase - - - 0.000006235 58.0
TH1_k127_3935869_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.104e-291 900.0
TH1_k127_3935869_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 604.0
TH1_k127_3935869_10 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 288.0
TH1_k127_3935869_11 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000007503 240.0
TH1_k127_3935869_12 oxidase, assembly K02258 - - 0.00000000000000000000000000000000000000000000000000000002017 203.0
TH1_k127_3935869_13 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000002412 161.0
TH1_k127_3935869_14 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000263 152.0
TH1_k127_3935869_15 signal sequence binding - - - 0.00000000000000000000001508 109.0
TH1_k127_3935869_16 - - - - 0.000000000000000000000952 102.0
TH1_k127_3935869_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 529.0
TH1_k127_3935869_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 482.0
TH1_k127_3935869_4 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 458.0
TH1_k127_3935869_5 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 439.0
TH1_k127_3935869_6 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 426.0
TH1_k127_3935869_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 417.0
TH1_k127_3935869_8 COG1718 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 350.0
TH1_k127_3935869_9 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 332.0
TH1_k127_39706_0 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 365.0
TH1_k127_39706_1 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000000000000000000008062 157.0
TH1_k127_39706_4 regulation of DNA-templated transcription, elongation - - - 0.00001542 50.0
TH1_k127_4018658_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1157.0
TH1_k127_4018658_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 1.291e-222 702.0
TH1_k127_4018658_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 411.0
TH1_k127_4018658_3 - - - - 0.000000000000000000000000000000000000000000000000000004241 193.0
TH1_k127_4018658_4 Protein required for attachment to host cells - - - 0.00000000000000000000000000003453 121.0
TH1_k127_4122293_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 514.0
TH1_k127_4122293_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000154 212.0
TH1_k127_4137829_0 Dehydrogenase E1 component K00164 - 1.2.4.2 1.338e-310 965.0
TH1_k127_4137829_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 609.0
TH1_k127_4137829_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 560.0
TH1_k127_4137829_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 497.0
TH1_k127_4137829_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0071704,GO:1901564,GO:1902494 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 489.0
TH1_k127_4137829_5 Gram-negative porin - - - 0.0000000000000000000000000000003704 133.0
TH1_k127_4140915_0 GMC oxidoreductase K06151 - 1.1.99.3 1.478e-242 760.0
TH1_k127_4140915_1 TIGRFAM RNA polymerase sigma factor RpoS K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 433.0
TH1_k127_4140915_10 AsmA family K07290 - - 0.000000000000006126 85.0
TH1_k127_4140915_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 335.0
TH1_k127_4140915_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 290.0
TH1_k127_4140915_4 amino acid-binding ACT domain protein K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000007868 245.0
TH1_k127_4140915_5 COG0739 Membrane proteins related to metalloendopeptidases K06194,K12943 GO:0000920,GO:0001896,GO:0005575,GO:0005623,GO:0008150,GO:0008219,GO:0009279,GO:0009987,GO:0012501,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0043085,GO:0044093,GO:0044462,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000004567 220.0
TH1_k127_4140915_6 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000000000000000007675 163.0
TH1_k127_4140915_7 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.00000000000000000000000000000000000008144 151.0
TH1_k127_4140915_8 Smr protein - - - 0.000000000000000000000000000000004028 134.0
TH1_k127_4140915_9 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000211 112.0
TH1_k127_4151832_0 Diguanylate cyclase - - - 1.608e-241 760.0
TH1_k127_4151832_1 associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 588.0
TH1_k127_4151832_10 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000001613 245.0
TH1_k127_4151832_11 SMART Signal transduction response regulator, receiver region - - - 0.00000000000000000000000000000000000000000000000000000000000000000002094 235.0
TH1_k127_4151832_12 TIGRFAM CRISPR-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001483 228.0
TH1_k127_4151832_13 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000000000000000000005039 187.0
TH1_k127_4151832_14 Part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000000000000001213 170.0
TH1_k127_4151832_15 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000004453 155.0
TH1_k127_4151832_16 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.00000000000000000000000002397 116.0
TH1_k127_4151832_17 - - - - 0.00000000000000000000000003528 115.0
TH1_k127_4151832_18 - - - - 0.00000000000000000001689 93.0
TH1_k127_4151832_19 - - - - 0.00000000000000001726 86.0
TH1_k127_4151832_2 Putative metallopeptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 519.0
TH1_k127_4151832_20 - - - - 0.000000000008049 69.0
TH1_k127_4151832_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 382.0
TH1_k127_4151832_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 357.0
TH1_k127_4151832_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 354.0
TH1_k127_4151832_6 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 322.0
TH1_k127_4151832_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 309.0
TH1_k127_4151832_8 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002563 272.0
TH1_k127_4151832_9 PFAM 2OG-Fe(II) oxygenase superfamily K07336 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006157 265.0
TH1_k127_4157483_0 type II secretion system protein E K02454,K02652,K12276 - - 1.913e-242 762.0
TH1_k127_4157483_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 1.181e-213 671.0
TH1_k127_4157483_10 PFAM toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000354 181.0
TH1_k127_4157483_11 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000006087 113.0
TH1_k127_4157483_12 Protein of unknown function (DUF2892) - - - 0.00000000000000000000002922 100.0
TH1_k127_4157483_13 - - - - 0.00000000000000000002453 91.0
TH1_k127_4157483_14 BolA-like protein - - - 0.0000000003301 65.0
TH1_k127_4157483_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18901 - - 0.000000002196 67.0
TH1_k127_4157483_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 606.0
TH1_k127_4157483_3 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 448.0
TH1_k127_4157483_4 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 381.0
TH1_k127_4157483_5 ABC transporter permease K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 336.0
TH1_k127_4157483_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 311.0
TH1_k127_4157483_7 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000176 240.0
TH1_k127_4157483_8 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000006454 209.0
TH1_k127_4157483_9 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000006298 184.0
TH1_k127_4194536_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1257.0
TH1_k127_4194536_1 ABC transporter transmembrane region K06147,K06148 - - 8.54e-245 769.0
TH1_k127_4194536_10 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 362.0
TH1_k127_4194536_11 Lytic murein transglycosylase K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 351.0
TH1_k127_4194536_12 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 347.0
TH1_k127_4194536_13 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 337.0
TH1_k127_4194536_14 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 306.0
TH1_k127_4194536_15 Protein kinase domain K11912,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005055 294.0
TH1_k127_4194536_16 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001053 268.0
TH1_k127_4194536_17 PFAM Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000004282 256.0
TH1_k127_4194536_18 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000001204 251.0
TH1_k127_4194536_19 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000001214 233.0
TH1_k127_4194536_2 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 8.527e-224 713.0
TH1_k127_4194536_20 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000006762 219.0
TH1_k127_4194536_21 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000461 205.0
TH1_k127_4194536_22 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000132 199.0
TH1_k127_4194536_23 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000001859 198.0
TH1_k127_4194536_24 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000008463 188.0
TH1_k127_4194536_25 Zinc-ribbon containing domain - - - 0.0000000000000000000000000000000000000000000000000981 183.0
TH1_k127_4194536_26 Thioredoxin - - - 0.00000000000000000000000000000000000000000000002252 176.0
TH1_k127_4194536_27 Pentapeptide - - - 0.0000000000000000000000000000000000000007679 151.0
TH1_k127_4194536_28 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000002089 102.0
TH1_k127_4194536_29 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000002857 106.0
TH1_k127_4194536_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 471.0
TH1_k127_4194536_30 Putative peptidoglycan binding domain - - - 0.00000002003 61.0
TH1_k127_4194536_31 PilZ domain - - - 0.00003421 49.0
TH1_k127_4194536_32 SEL1L2 ERAD E3 ligase adaptor subunit K14026 GO:0000151,GO:0000153,GO:0000835,GO:0000836,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008593,GO:0009056,GO:0009057,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0010646,GO:0010648,GO:0012505,GO:0016020,GO:0019538,GO:0019941,GO:0023051,GO:0023057,GO:0030163,GO:0030433,GO:0031410,GO:0031982,GO:0031984,GO:0032991,GO:0033554,GO:0034976,GO:0036503,GO:0042175,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045746,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051603,GO:0051716,GO:0065007,GO:0071704,GO:0097708,GO:0098796,GO:0098827,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1902494,GO:1990234 - 0.0003362 49.0
TH1_k127_4194536_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 470.0
TH1_k127_4194536_5 Belongs to the peptidase S11 family K07258 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 451.0
TH1_k127_4194536_6 belongs to the carbohydrate kinase PfkB family K00847,K00892 - 2.7.1.4,2.7.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 427.0
TH1_k127_4194536_7 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 370.0
TH1_k127_4194536_8 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 357.0
TH1_k127_4194536_9 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 360.0
TH1_k127_42016_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 9.947e-309 947.0
TH1_k127_42016_1 PFAM von Willebrand factor type A - - - 8.05e-226 707.0
TH1_k127_42016_2 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 552.0
TH1_k127_42016_3 PFAM AAA domain (dynein-related subfamily) K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 502.0
TH1_k127_42016_4 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 377.0
TH1_k127_42016_5 Prolyl oligopeptidase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000001108 228.0
TH1_k127_42016_6 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000107 208.0
TH1_k127_42016_7 - - - - 0.00000000000000000000000000000000000000000000000004512 179.0
TH1_k127_42016_8 Protein of unknown function (DUF3015) - - - 0.0000000000000000000000000000000000000000000005922 177.0
TH1_k127_4333356_0 negative regulation of hippo signaling - - - 4.261e-231 747.0
TH1_k127_4333356_1 PFAM Type II secretion system protein E K02670 - - 4.655e-200 628.0
TH1_k127_4333356_2 Tfp pilus assembly protein, pilus retraction ATPase PilT K02669 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 604.0
TH1_k127_4333356_3 PFAM Type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 505.0
TH1_k127_4333356_4 TIGRFAM Diguanylate cyclase K13069 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000002832 224.0
TH1_k127_4333356_5 Nucleoside recognition K06373 - - 0.000000000000000000000000000000000000000000000000000000003429 216.0
TH1_k127_4333356_6 Nucleoside recognition K06374 - - 0.00000000000000000000000000000000000000000000000000000002607 205.0
TH1_k127_4333356_7 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000006588 184.0
TH1_k127_4337606_0 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 2.042e-270 853.0
TH1_k127_4337606_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.474e-252 781.0
TH1_k127_4337606_10 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000009258 241.0
TH1_k127_4337606_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000003122 156.0
TH1_k127_4337606_12 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000003664 100.0
TH1_k127_4337606_13 - - - - 0.000008758 48.0
TH1_k127_4337606_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.754e-242 752.0
TH1_k127_4337606_3 Diguanylate cyclase - - - 1.092e-197 659.0
TH1_k127_4337606_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 507.0
TH1_k127_4337606_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 323.0
TH1_k127_4337606_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 295.0
TH1_k127_4337606_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 283.0
TH1_k127_4337606_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002293 275.0
TH1_k127_4337606_9 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002208 244.0
TH1_k127_4436756_0 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000003159 228.0
TH1_k127_4436756_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000001079 224.0
TH1_k127_4436756_2 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000002414 158.0
TH1_k127_4436756_3 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000000000004888 154.0
TH1_k127_4436756_4 PFAM conserved - - - 0.00000000000000000007021 96.0
TH1_k127_4504674_0 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 5.914e-205 649.0
TH1_k127_4504674_1 TIGRFAM cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008129 354.0
TH1_k127_4504674_10 Integral membrane protein (DUF2244) - - - 0.000000000000000000007905 99.0
TH1_k127_4504674_2 Domain of unknown function (DUF4478) K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 317.0
TH1_k127_4504674_3 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000001011 216.0
TH1_k127_4504674_4 protein conserved in bacteria K09922 - - 0.0000000000000000000000000000000000000000000000000000006469 194.0
TH1_k127_4504674_5 alpha-ribazole phosphatase activity - - - 0.0000000000000000000000000000000000000000000002126 173.0
TH1_k127_4504674_6 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000001339 174.0
TH1_k127_4504674_7 Ethanolamine utilisation protein EutQ K06995 - - 0.00000000000000000000000000000000000001075 146.0
TH1_k127_4504674_8 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000000000000002902 127.0
TH1_k127_4504674_9 Alternative locus ID K15383 - - 0.00000000000000000000009731 102.0
TH1_k127_4508363_0 Belongs to the heme-copper respiratory oxidase family K00404 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 1.988e-258 802.0
TH1_k127_4508363_1 TIGRFAM cytochrome c oxidase accessory protein - - - 5.069e-200 632.0
TH1_k127_4508363_10 Cbb3-type cytochrome oxidase component FixQ - - - 0.0000000000000000004187 88.0
TH1_k127_4508363_2 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 585.0
TH1_k127_4508363_3 Cation transporter/ATPase, N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 491.0
TH1_k127_4508363_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 458.0
TH1_k127_4508363_5 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 372.0
TH1_k127_4508363_6 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 348.0
TH1_k127_4508363_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 324.0
TH1_k127_4508363_8 PFAM FixH - - - 0.0000000000000000000000000000000000006054 148.0
TH1_k127_4508363_9 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.0000000000000000000002206 97.0
TH1_k127_4580864_0 Arginine K01478 - 3.5.3.6 2.798e-224 699.0
TH1_k127_4580864_1 C4-dicarboxylate anaerobic carrier - - - 4.532e-199 630.0
TH1_k127_4580864_10 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 313.0
TH1_k127_4580864_11 Sigma-54 interaction domain K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 301.0
TH1_k127_4580864_12 PFAM Flagellar assembly protein FliH K02411 - - 0.000000000000000000000000003456 118.0
TH1_k127_4580864_13 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000000000000000001104 106.0
TH1_k127_4580864_14 Flagellar FliJ protein K02413 - - 0.000000000000006032 80.0
TH1_k127_4580864_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K13252 - 2.1.3.3,2.1.3.6 2.17e-198 621.0
TH1_k127_4580864_3 amino acid K03294,K03759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 611.0
TH1_k127_4580864_4 ATPase FliI YscN family K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 582.0
TH1_k127_4580864_5 Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 494.0
TH1_k127_4580864_6 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 437.0
TH1_k127_4580864_7 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 419.0
TH1_k127_4580864_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 337.0
TH1_k127_4580864_9 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 319.0
TH1_k127_4595615_0 EAL domain - - - 0.0 1027.0
TH1_k127_4595615_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.274e-254 797.0
TH1_k127_4595615_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 431.0
TH1_k127_4595615_3 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004196 271.0
TH1_k127_4626722_0 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 548.0
TH1_k127_4626722_1 double-strand break repair protein AddB K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 561.0
TH1_k127_4626722_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 402.0
TH1_k127_4626722_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001345 239.0
TH1_k127_4626722_4 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000002069 147.0
TH1_k127_4626722_5 Universal stress protein K06149 - - 0.00000000000000000000000000000003469 131.0
TH1_k127_4626722_6 CHAD - - - 0.0000000000000000000000000000009768 133.0
TH1_k127_4656709_0 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 1.528e-265 829.0
TH1_k127_4656709_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 493.0
TH1_k127_4749850_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 5.772e-210 677.0
TH1_k127_4749850_1 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K02805,K18653 - 2.6.1.104,2.6.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 567.0
TH1_k127_4749850_10 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000008463 207.0
TH1_k127_4749850_11 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000002547 167.0
TH1_k127_4749850_12 Outer membrane protein (OmpH-like) - - - 0.00000001702 63.0
TH1_k127_4749850_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 523.0
TH1_k127_4749850_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 488.0
TH1_k127_4749850_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 451.0
TH1_k127_4749850_5 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 450.0
TH1_k127_4749850_6 Histidine kinase K07678 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 386.0
TH1_k127_4749850_7 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 342.0
TH1_k127_4749850_8 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 323.0
TH1_k127_4749850_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000297 261.0
TH1_k127_4753524_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 8.876e-247 771.0
TH1_k127_4753524_1 Belongs to the GARS family K01945,K13713 GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 4.39e-199 627.0
TH1_k127_4753524_2 cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 506.0
TH1_k127_4753524_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 443.0
TH1_k127_4753524_4 TfoX N-terminal domain K07343 - - 0.0000000000000000000000000000000000002054 143.0
TH1_k127_4753524_5 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000003973 95.0
TH1_k127_4753524_6 TM2 domain - - - 0.000000000000001324 87.0
TH1_k127_4762118_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 523.0
TH1_k127_4762118_1 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 482.0
TH1_k127_4762118_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000302 138.0
TH1_k127_4762118_3 PTS system fructose IIA component K02793,K02794 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0008645,GO:0008982,GO:0009401,GO:0009987,GO:0015144,GO:0015145,GO:0015149,GO:0015578,GO:0015749,GO:0015761,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0022870,GO:0031224,GO:0031226,GO:0034219,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046323,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098657,GO:0098704,GO:0098708,GO:0098739,GO:1904659 2.7.1.191 0.00000000000000000000000000000001751 130.0
TH1_k127_4762118_4 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.00000000000000000000000000007566 117.0
TH1_k127_4762118_5 Displays ATPase and GTPase activities K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000004814 85.0
TH1_k127_4786287_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 323.0
TH1_k127_4786287_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 291.0
TH1_k127_4786287_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003177 273.0
TH1_k127_4786287_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000005972 164.0
TH1_k127_4786287_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 GO:0003674,GO:0003824,GO:0008119,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008757,GO:0010035,GO:0010038,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0046690,GO:0050896 2.1.1.67 0.000000000000000000000000000000000000000008433 157.0
TH1_k127_4808609_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1115.0
TH1_k127_4808609_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 574.0
TH1_k127_4808609_10 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000000000000007332 222.0
TH1_k127_4808609_11 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000000000000000000000000000000000000004306 191.0
TH1_k127_4808609_12 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000009159 191.0
TH1_k127_4808609_13 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000001533 171.0
TH1_k127_4808609_14 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000312 165.0
TH1_k127_4808609_15 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.000000000000000000000000000000000000000000338 167.0
TH1_k127_4808609_16 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000331 125.0
TH1_k127_4808609_17 bacterial-type flagellum organization K02398 - - 0.000000144 57.0
TH1_k127_4808609_18 FlgN protein K02399 - - 0.0001373 49.0
TH1_k127_4808609_2 basal body rod protein K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 402.0
TH1_k127_4808609_3 basal body rod protein K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 379.0
TH1_k127_4808609_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 377.0
TH1_k127_4808609_5 COG0835 Chemotaxis signal transduction protein K03415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 374.0
TH1_k127_4808609_6 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 339.0
TH1_k127_4808609_7 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 285.0
TH1_k127_4808609_8 TIGRFAM flagellar basal-body rod protein FlgF K02391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001401 258.0
TH1_k127_4808609_9 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000001182 253.0
TH1_k127_4813978_0 cell wall organization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 504.0
TH1_k127_4813978_1 ATP adenylyltransferase (5',5''-P-1,P-4-tetraphosphate phosphorylase II) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 351.0
TH1_k127_4832822_0 Cytochrome c bacterial - - - 2.329e-302 933.0
TH1_k127_4832822_1 - K07112 - - 2.627e-241 750.0
TH1_k127_4832822_10 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000003454 220.0
TH1_k127_4832822_12 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000001939 208.0
TH1_k127_4832822_13 DSBA-like thioredoxin domain K03673 - - 0.0000000000000000000000000000000000001936 145.0
TH1_k127_4832822_14 MlaD protein K02067 - - 0.000000000000000000000000000000000003198 149.0
TH1_k127_4832822_15 - - - - 0.000000000000000000000000001183 119.0
TH1_k127_4832822_16 Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000001319 68.0
TH1_k127_4832822_17 Permease MlaE K02066 - - 0.0000001065 54.0
TH1_k127_4832822_2 Cytochrome c bacterial - - - 2.022e-214 677.0
TH1_k127_4832822_3 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 601.0
TH1_k127_4832822_4 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 386.0
TH1_k127_4832822_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 349.0
TH1_k127_4832822_6 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 315.0
TH1_k127_4832822_7 (GGDEF) domain K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006386 296.0
TH1_k127_4832822_8 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001194 267.0
TH1_k127_4832822_9 Domain of unknown function (DUF3393) - - - 0.00000000000000000000000000000000000000000000000000000000000001582 229.0
TH1_k127_4838116_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2170.0
TH1_k127_4838116_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 2168.0
TH1_k127_4838116_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1172.0
TH1_k127_4838116_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000089 244.0
TH1_k127_4838116_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000001169 229.0
TH1_k127_4838116_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000005352 229.0
TH1_k127_4838116_6 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000002067 227.0
TH1_k127_4838116_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000001336 179.0
TH1_k127_4838116_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000007077 85.0
TH1_k127_4883007_0 alcohol dehydrogenase K12957 GO:0003674,GO:0003824,GO:0004033,GO:0005488,GO:0008106,GO:0008150,GO:0008152,GO:0008270,GO:0016491,GO:0016614,GO:0016616,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 506.0
TH1_k127_4883007_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 406.0
TH1_k127_4883007_10 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.0001601 48.0
TH1_k127_4883007_2 COG0784 FOG CheY-like receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 392.0
TH1_k127_4883007_3 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003698 258.0
TH1_k127_4883007_4 Belongs to the UPF0502 family K09915 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001192 256.0
TH1_k127_4883007_5 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000142 248.0
TH1_k127_4883007_7 Putative MetA-pathway of phenol degradation - - - 0.00000000000001168 76.0
TH1_k127_4883007_8 TIGRFAM phosphoesterase, MJ0936 family - - - 0.0000000004397 68.0
TH1_k127_4883007_9 Domain of unknown function (DUF4124) - - - 0.0000008285 58.0
TH1_k127_4889833_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.543e-210 660.0
TH1_k127_4889833_1 The short-chain dehydrogenases reductases - - - 0.0000000000000000000000000000000000000000000000000008355 192.0
TH1_k127_4914214_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 475.0
TH1_k127_4914214_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 355.0
TH1_k127_4914214_10 COG0659 Sulfate permease and related transporters (MFS superfamily K03321 - - 0.000000000008388 69.0
TH1_k127_4914214_2 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 304.0
TH1_k127_4914214_3 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001379 278.0
TH1_k127_4914214_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001483 228.0
TH1_k127_4914214_5 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000002402 210.0
TH1_k127_4914214_6 - - - - 0.000000000000000000000000000000000000002 155.0
TH1_k127_4914214_7 - - - - 0.000000000000000000000000000000000005087 140.0
TH1_k127_4914214_8 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000003221 116.0
TH1_k127_495541_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 599.0
TH1_k127_495541_1 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000000000000000002085 207.0
TH1_k127_495541_2 Belongs to the Nudix hydrolase family. NudJ subfamily K03574,K12152 GO:0003674,GO:0003824,GO:0004787,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0017111 3.6.1.55 0.000000000000006999 78.0
TH1_k127_495541_3 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00001897 49.0
TH1_k127_4968873_0 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 439.0
TH1_k127_4968873_1 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 358.0
TH1_k127_4968873_10 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0033554,GO:0033592,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 0.000007525 49.0
TH1_k127_4968873_2 His Kinase A (phospho-acceptor) domain K02484,K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 341.0
TH1_k127_4968873_3 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 296.0
TH1_k127_4968873_4 TIGRFAM alpha-L-glutamate ligase-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006749 250.0
TH1_k127_4968873_5 cyclic-guanylate-specific phosphodiesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000005565 240.0
TH1_k127_4968873_6 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000002543 224.0
TH1_k127_4968873_7 Redoxin - - - 0.0000000000000000000000000000000000000000002812 162.0
TH1_k127_4968873_8 Tetratricopeptide repeat K12600 - - 0.000000000000000000000002136 119.0
TH1_k127_4968873_9 Domain of unknown function (DUF4266) - - - 0.00000000000000001369 85.0
TH1_k127_4987028_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1239.0
TH1_k127_4987028_1 COG0493 NADPH-dependent glutamate synthase beta chain and K00266 - 1.4.1.13,1.4.1.14 4.816e-212 668.0
TH1_k127_5007694_0 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 418.0
TH1_k127_5007694_1 DoxX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001304 262.0
TH1_k127_5007694_2 - - - - 0.0000000000000000000000000000000000000000000000000001137 190.0
TH1_k127_5007694_3 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000003442 167.0
TH1_k127_5007694_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000004341 162.0
TH1_k127_5007694_6 Transport permease protein K01992 - - 0.0000000000004289 72.0
TH1_k127_5007694_7 - - - - 0.000001355 54.0
TH1_k127_5035785_0 Phosphate transport system permease protein K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 504.0
TH1_k127_5035785_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 445.0
TH1_k127_5035785_2 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 313.0
TH1_k127_5035785_3 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 286.0
TH1_k127_5035785_4 MazG-like family - - - 0.00000000000000000000000000000000000000002323 157.0
TH1_k127_5035785_5 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.000000000000001519 77.0
TH1_k127_5035785_6 - - - - 0.00007225 51.0
TH1_k127_5039395_0 magnesium chelatase K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 584.0
TH1_k127_5039395_1 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 434.0
TH1_k127_5039395_2 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000000002598 203.0
TH1_k127_5039395_3 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000001615 135.0
TH1_k127_5039395_4 Membrane fusogenic activity K09806 - - 0.0000000000000002716 81.0
TH1_k127_5083736_0 transporter component K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 511.0
TH1_k127_5083736_1 Oxygen tolerance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 346.0
TH1_k127_5083736_2 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 322.0
TH1_k127_5083736_3 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517,K12974 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000004853 254.0
TH1_k127_5083736_4 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.00000000000000000000000000000000000000000000000003195 188.0
TH1_k127_5083736_5 von Willebrand factor, type A K07114 - - 0.000000000594 62.0
TH1_k127_5087815_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1100.0
TH1_k127_5087815_1 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 340.0
TH1_k127_5087815_2 PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000007449 225.0
TH1_k127_5103897_0 PFAM malic K00029 - 1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 590.0
TH1_k127_5103897_1 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 353.0
TH1_k127_5103897_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 313.0
TH1_k127_5103897_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 309.0
TH1_k127_5103897_4 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000001009 220.0
TH1_k127_5103897_5 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000000000000000000000001004 173.0
TH1_k127_5103897_6 nuclease - - - 0.0000000000000000000000000000000000000000000003095 179.0
TH1_k127_5103897_7 Binds the 23S rRNA K02909 - - 0.0000000000000000000000006439 107.0
TH1_k127_5117130_0 Tetratricopeptide repeat - - - 0.0 1066.0
TH1_k127_5117130_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.447e-314 975.0
TH1_k127_5117130_10 phospholipase K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 321.0
TH1_k127_5117130_11 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 307.0
TH1_k127_5117130_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001089 289.0
TH1_k127_5117130_13 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000002894 239.0
TH1_k127_5117130_14 - - - - 0.0000000000000000000000000000000000000000000000000000003349 198.0
TH1_k127_5117130_15 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000004046 194.0
TH1_k127_5117130_16 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000001362 183.0
TH1_k127_5117130_17 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000243 166.0
TH1_k127_5117130_18 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000006414 165.0
TH1_k127_5117130_19 Belongs to the protease inhibitor I11 (ecotin) family K08276 - - 0.000000000000000000000000000000000002436 145.0
TH1_k127_5117130_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.243e-285 900.0
TH1_k127_5117130_20 OmpA family K02557 - - 0.000000000000000000000000000000007188 140.0
TH1_k127_5117130_21 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001096 130.0
TH1_k127_5117130_22 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000001432 127.0
TH1_k127_5117130_23 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000003845 124.0
TH1_k127_5117130_24 - - - - 0.000000000000000000000000007666 113.0
TH1_k127_5117130_25 - - - - 0.00000000000000000000000003903 115.0
TH1_k127_5117130_26 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000003482 112.0
TH1_k127_5117130_28 - - - - 0.000000000006338 65.0
TH1_k127_5117130_29 surface antigen - - - 0.0009721 46.0
TH1_k127_5117130_3 isomerase - - - 8.138e-283 889.0
TH1_k127_5117130_4 Participates in both transcription termination and antitermination K02600 - - 5.481e-223 701.0
TH1_k127_5117130_5 Tetratricopeptide repeat - - - 3.64e-210 672.0
TH1_k127_5117130_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 594.0
TH1_k127_5117130_7 Phospholipase D Transphosphatidylase K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 584.0
TH1_k127_5117130_8 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 432.0
TH1_k127_5117130_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 376.0
TH1_k127_5132224_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.0 1348.0
TH1_k127_5132224_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 1.704e-271 856.0
TH1_k127_5132224_10 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000001913 100.0
TH1_k127_5132224_11 Putative diguanylate phosphodiesterase - - - 0.0001155 49.0
TH1_k127_5132224_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 6.412e-267 839.0
TH1_k127_5132224_3 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 598.0
TH1_k127_5132224_4 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 343.0
TH1_k127_5132224_5 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000413 263.0
TH1_k127_5132224_6 efflux transmembrane transporter activity K15725 - - 0.0000000000000000000000000000000000000000000000000000000000002004 228.0
TH1_k127_5132224_7 pfam ammecr1 - - - 0.000000000000000000000000000000000000000000000000000000000001876 214.0
TH1_k127_5132224_8 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000002784 198.0
TH1_k127_5132224_9 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000001014 119.0
TH1_k127_5157045_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 514.0
TH1_k127_5157045_1 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007388 426.0
TH1_k127_5157045_2 Domain of unknown function (DUF4824) - - - 0.0000000000000000000000000000000000000000000000291 180.0
TH1_k127_5157045_3 dNA-binding protein - - - 0.0000000000000000001845 90.0
TH1_k127_5160884_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 507.0
TH1_k127_5160884_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 358.0
TH1_k127_5160884_2 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 323.0
TH1_k127_5160884_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000001502 227.0
TH1_k127_5160884_4 PFAM 20S proteasome, A and B subunits K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000001937 226.0
TH1_k127_5160884_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000002713 165.0
TH1_k127_5160884_6 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000005098 102.0
TH1_k127_5160884_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000008426 60.0
TH1_k127_5160884_8 Belongs to the sulfur carrier protein TusA family - - - 0.000002145 53.0
TH1_k127_5164746_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.914e-279 881.0
TH1_k127_5164746_1 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 413.0
TH1_k127_5164746_2 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 304.0
TH1_k127_5164746_3 subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000001238 251.0
TH1_k127_5164746_4 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000006677 199.0
TH1_k127_5184830_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 371.0
TH1_k127_5184830_1 P-type atpase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 362.0
TH1_k127_5184830_2 UBA THIF-type NAD FAD binding K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 334.0
TH1_k127_5184830_3 His Kinase A (phosphoacceptor) domain K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000008178 229.0
TH1_k127_5184830_4 helix_turn_helix, mercury resistance K19591,K19592 - - 0.00000000000000000000000000000000000000000000005835 173.0
TH1_k127_5205778_0 TIGRFAM SagB-type dehydrogenase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 610.0
TH1_k127_5205778_1 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 440.0
TH1_k127_5205778_10 AMP-binding enzyme C-terminal domain - - - 0.0000009011 59.0
TH1_k127_5205778_2 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 341.0
TH1_k127_5205778_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 326.0
TH1_k127_5205778_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001518 275.0
TH1_k127_5205778_5 molybdenum ABC transporter, periplasmic K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001211 258.0
TH1_k127_5205778_6 Sterol carrier protein - - - 0.00000000000000000000000000000000008948 137.0
TH1_k127_5205778_7 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000009548 132.0
TH1_k127_5205778_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000005185 135.0
TH1_k127_5205778_9 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.0000000000000000001189 95.0
TH1_k127_5291343_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1379.0
TH1_k127_5291343_1 Cytochrome c-type biogenesis protein CcmF K02198 - - 1.306e-288 899.0
TH1_k127_5291343_10 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000001122 181.0
TH1_k127_5291343_11 Ferredoxin-type protein NapF K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.000000000000000000000000000000000000000000002318 171.0
TH1_k127_5291343_12 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0044237,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000003724 162.0
TH1_k127_5291343_13 Cytochrome C biogenesis protein - - - 0.0000000000000000000000000000000000000347 149.0
TH1_k127_5291343_14 glutathione-regulated potassium exporter activity - - - 0.000000000000000000000000000000005563 131.0
TH1_k127_5291343_15 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000000000146 89.0
TH1_k127_5291343_16 NapD protein K02570 - - 0.0000000000001412 73.0
TH1_k127_5291343_17 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.0000008514 52.0
TH1_k127_5291343_2 4Fe-4S binding domain K02573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 418.0
TH1_k127_5291343_3 TIGRFAM ferredoxin-type protein, NapH MauN family K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 394.0
TH1_k127_5291343_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 379.0
TH1_k127_5291343_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 290.0
TH1_k127_5291343_6 PFAM NapC NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 282.0
TH1_k127_5291343_7 TIGRFAM Cytochrome c-type biogenesis protein CcmI K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007277 262.0
TH1_k127_5291343_8 TIGRFAM periplasmic protein thiol K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000392 233.0
TH1_k127_5291343_9 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000001787 207.0
TH1_k127_536457_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 490.0
TH1_k127_536457_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 392.0
TH1_k127_536457_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 381.0
TH1_k127_536457_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 301.0
TH1_k127_536457_4 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000001665 234.0
TH1_k127_536457_5 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004052 233.0
TH1_k127_536457_6 PFAM ApaG domain protein K06195 - - 0.0000000000000000000000000000000000000000000000000001126 188.0
TH1_k127_536457_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000005187 181.0
TH1_k127_5397488_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 1.116e-298 926.0
TH1_k127_5397488_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.952e-275 855.0
TH1_k127_5397488_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 347.0
TH1_k127_5397488_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 301.0
TH1_k127_5397488_12 Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle K00564 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 294.0
TH1_k127_5397488_13 lysine 2,3-aminomutase K19810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009951 277.0
TH1_k127_5397488_14 Belongs to the pseudouridine synthase RsuA family K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000002272 257.0
TH1_k127_5397488_15 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000001879 201.0
TH1_k127_5397488_16 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000001159 182.0
TH1_k127_5397488_17 Peptidase S24-like - - - 0.000000000000000000000000000009136 121.0
TH1_k127_5397488_18 - - - - 0.000000000001813 72.0
TH1_k127_5397488_2 - - - - 2.49e-265 829.0
TH1_k127_5397488_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 2.734e-209 659.0
TH1_k127_5397488_4 PFAM EAL domain K21025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 607.0
TH1_k127_5397488_5 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00651 - 2.3.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 550.0
TH1_k127_5397488_6 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 504.0
TH1_k127_5397488_7 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 445.0
TH1_k127_5397488_8 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 389.0
TH1_k127_5397488_9 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 374.0
TH1_k127_5437648_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 435.0
TH1_k127_5437648_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 339.0
TH1_k127_5437648_10 Cytochrome c K17223 - - 0.0000000000000000000000000000000007989 133.0
TH1_k127_5437648_11 PFAM Rhodanese-like - - - 0.0000000000000000000000000002589 117.0
TH1_k127_5437648_2 Thiosulfate-oxidizing multienzyme system protein SoxA K17222,K19713 - 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 338.0
TH1_k127_5437648_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 311.0
TH1_k127_5437648_4 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008364 257.0
TH1_k127_5437648_5 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.000000000000000000000000000000000000000000000000000000000000000000008286 251.0
TH1_k127_5437648_6 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000009177 169.0
TH1_k127_5437648_7 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000003496 170.0
TH1_k127_5437648_8 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000005061 149.0
TH1_k127_5437648_9 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000003847 139.0
TH1_k127_5443124_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.477e-297 925.0
TH1_k127_5443124_1 4Fe-4S dicluster domain - - - 5.002e-256 797.0
TH1_k127_5443124_10 response regulator receiver K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000939 284.0
TH1_k127_5443124_11 TIGRFAM sulfur relay protein TusD DsrE K07235 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0019417,GO:0044237,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000003844 221.0
TH1_k127_5443124_12 Belongs to the DsrF TusC family K07236 - - 0.000000000000000000000000000000000000000000000000000000000001098 211.0
TH1_k127_5443124_13 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000000000000000000000008674 207.0
TH1_k127_5443124_14 sulfur relay protein TusB DsrH K07237 - - 0.000000000000000000000000000000000000309 143.0
TH1_k127_5443124_15 PFAM Rhodanese-like - - - 0.00000000000000000000000000001031 120.0
TH1_k127_5443124_16 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000001258 118.0
TH1_k127_5443124_17 - - - - 0.00000000000000000000000000168 118.0
TH1_k127_5443124_19 TIGRFAM CRISPR-associated protein - - - 0.00000000000000001039 87.0
TH1_k127_5443124_2 reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 8.703e-240 745.0
TH1_k127_5443124_3 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 4.126e-223 692.0
TH1_k127_5443124_4 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 576.0
TH1_k127_5443124_5 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 481.0
TH1_k127_5443124_6 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 361.0
TH1_k127_5443124_7 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 326.0
TH1_k127_5443124_8 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 311.0
TH1_k127_5443124_9 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000128 288.0
TH1_k127_5457341_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 492.0
TH1_k127_5457341_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 295.0
TH1_k127_5457341_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000004387 145.0
TH1_k127_5457341_3 - - - - 0.0001028 47.0
TH1_k127_5472172_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 7.229e-194 610.0
TH1_k127_5472172_1 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 297.0
TH1_k127_5472172_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006424 255.0
TH1_k127_5472172_3 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000001036 53.0
TH1_k127_54791_0 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 405.0
TH1_k127_54791_1 Major facilitator superfamily K08227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 404.0
TH1_k127_54791_2 SMART Phospholipid glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000003471 266.0
TH1_k127_5486023_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1029.0
TH1_k127_5486023_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 4.294e-212 662.0
TH1_k127_5486023_2 FAD dependent oxidoreductase K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.181e-207 650.0
TH1_k127_5486023_3 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 614.0
TH1_k127_5486023_4 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 505.0
TH1_k127_5486023_5 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 351.0
TH1_k127_5486023_6 PFAM Glycosyl transferase family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000004041 190.0
TH1_k127_5486023_7 Chemoreceptor zinc-binding domain - - - 0.0000000000000000000000000000000002267 136.0
TH1_k127_5486023_8 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000009188 115.0
TH1_k127_5488430_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 326.0
TH1_k127_5488430_1 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001398 260.0
TH1_k127_5488430_2 1-aminocyclopropane-1-carboxylate deaminase K01505 - 3.5.99.7 0.0000000000000000000000000000000000000000000000000000000000000000000005264 243.0
TH1_k127_5506242_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 426.0
TH1_k127_5506242_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 349.0
TH1_k127_5506242_2 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000004897 233.0
TH1_k127_5506242_3 uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000001359 219.0
TH1_k127_5506242_4 tonb protein K03832 - - 0.0000000000000000000000000000000000000000000000000000000000009419 220.0
TH1_k127_5506242_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000005539 146.0
TH1_k127_5506242_6 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000006939 58.0
TH1_k127_5572866_0 permeases of the drug metabolite transporter (Dmt) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 482.0
TH1_k127_5572866_1 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000003813 214.0
TH1_k127_5572866_2 Adenylate cyclase, class-I K05851 - 4.6.1.1 0.000000000000008034 88.0
TH1_k127_562586_0 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 542.0
TH1_k127_562586_1 Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs K06219 GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097697,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009427 280.0
TH1_k127_562586_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000001004 222.0
TH1_k127_562586_3 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000001988 216.0
TH1_k127_562586_4 regulatory protein, arsR K03892 - - 0.000000000000000000000000000000000000000002179 158.0
TH1_k127_562586_5 Glycosyltransferase Family 4 K00786 - - 0.00000008421 55.0
TH1_k127_5654341_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 4.054e-218 693.0
TH1_k127_5654341_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.6.1.62 3.886e-196 619.0
TH1_k127_5654341_10 membrane - - - 0.00000000000000000000000000000002527 136.0
TH1_k127_5654341_12 - - - - 0.00001791 49.0
TH1_k127_5654341_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 604.0
TH1_k127_5654341_3 Binding-protein-dependent transport system inner membrane component K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 467.0
TH1_k127_5654341_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 450.0
TH1_k127_5654341_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 407.0
TH1_k127_5654341_6 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000001294 216.0
TH1_k127_5654341_7 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000009331 215.0
TH1_k127_5654341_8 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000003683 135.0
TH1_k127_5654341_9 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000001365 130.0
TH1_k127_5677184_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 2.671e-266 833.0
TH1_k127_5677184_1 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 576.0
TH1_k127_5677184_10 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.0000000000000000000000000113 111.0
TH1_k127_5677184_11 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 - 0.0000000000000000000000000173 108.0
TH1_k127_5677184_12 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000001379 119.0
TH1_k127_5677184_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 475.0
TH1_k127_5677184_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 402.0
TH1_k127_5677184_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 316.0
TH1_k127_5677184_5 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000000000000000000000000000001036 204.0
TH1_k127_5677184_6 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 - - 0.000000000000000000000000000000000000000000000009449 173.0
TH1_k127_5677184_7 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000004606 177.0
TH1_k127_5677184_8 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 0.000000000000000000000000000000000000000004738 160.0
TH1_k127_5677184_9 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000005155 153.0
TH1_k127_5720535_0 chemotaxis protein K03407 - 2.7.13.3 5.336e-220 700.0
TH1_k127_5720535_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 584.0
TH1_k127_5720535_10 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 318.0
TH1_k127_5720535_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001845 300.0
TH1_k127_5720535_12 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003062 272.0
TH1_k127_5720535_13 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009062 256.0
TH1_k127_5720535_14 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000002376 205.0
TH1_k127_5720535_15 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000006049 204.0
TH1_k127_5720535_16 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000002316 183.0
TH1_k127_5720535_17 PFAM CheW-like K03408 - - 0.000000000000000000000000000000000000000000000002494 177.0
TH1_k127_5720535_18 PFAM CheW-like K03408 - - 0.000000000000000000000000000000000000000000000006248 177.0
TH1_k127_5720535_19 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000003262 185.0
TH1_k127_5720535_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 525.0
TH1_k127_5720535_20 Histidine kinase - - - 0.000000000000000000000000000002723 139.0
TH1_k127_5720535_21 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K20978 - - 0.00000000000000000000000002169 111.0
TH1_k127_5720535_22 phosphorelay signal transduction system - - - 0.000000000000000000000001477 107.0
TH1_k127_5720535_24 Flagellar hook-length control protein K02414 - - 0.00000000000000000000003921 113.0
TH1_k127_5720535_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 510.0
TH1_k127_5720535_4 COG2202 FOG PAS PAC domain K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 534.0
TH1_k127_5720535_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 521.0
TH1_k127_5720535_6 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 436.0
TH1_k127_5720535_7 GGDEF domain K01768,K07315,K20977 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 434.0
TH1_k127_5720535_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 334.0
TH1_k127_5720535_9 FimV C-terminal K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 365.0
TH1_k127_5767043_0 Cache_2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 509.0
TH1_k127_5767043_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000005912 207.0
TH1_k127_5779335_0 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95 C K02336 - 2.7.7.7 6.923e-265 837.0
TH1_k127_5779335_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 3.309e-197 625.0
TH1_k127_5779335_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 466.0
TH1_k127_5779335_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 292.0
TH1_k127_5779335_4 NAD-dependent epimerase dehydratase K01784,K08678,K12454 - 4.1.1.35,5.1.3.10,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000004514 254.0
TH1_k127_5779335_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000003655 249.0
TH1_k127_5779335_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000001058 206.0
TH1_k127_5779335_7 Peptidyl-prolyl cis-trans K03775 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010467,GO:0016151,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022417,GO:0031647,GO:0035821,GO:0036211,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043963,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0046872,GO:0046914,GO:0050821,GO:0050896,GO:0050897,GO:0051082,GO:0051604,GO:0051701,GO:0051704,GO:0051817,GO:0052027,GO:0052250,GO:0065007,GO:0065008,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000000000000000000009479 182.0
TH1_k127_5779335_8 - - - - 0.000000000000000000000000000000000008746 148.0
TH1_k127_5779335_9 - - - - 0.000000000000001517 79.0
TH1_k127_5831906_0 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 462.0
TH1_k127_5831906_1 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000005646 258.0
TH1_k127_5831906_2 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000002574 97.0
TH1_k127_5831906_3 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.00000000000001563 77.0
TH1_k127_5879050_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 3.941e-199 629.0
TH1_k127_5879050_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 604.0
TH1_k127_5879050_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.00000000000000000005648 90.0
TH1_k127_5924984_0 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 327.0
TH1_k127_5924984_1 PFAM Lipocalin family protein K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004885 265.0
TH1_k127_5924984_2 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 260.0
TH1_k127_5924984_3 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000008665 219.0
TH1_k127_5924984_4 Domain of unknown function (DUF4153) - - - 0.00000000000000000000000006321 113.0
TH1_k127_5924984_5 - - - - 0.000001654 57.0
TH1_k127_5956933_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 452.0
TH1_k127_5956933_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 323.0
TH1_k127_5956933_2 CBS-domain-containing membrane protein K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 289.0
TH1_k127_5956933_3 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002112 246.0
TH1_k127_5956933_4 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000003479 189.0
TH1_k127_5956933_5 Sodium/hydrogen exchanger family K03455,K11747 - - 0.0002643 43.0
TH1_k127_5983831_0 ATPase domain of DNA mismatch repair MUTS family K03555 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 0.0 1085.0
TH1_k127_5983831_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 507.0
TH1_k127_5983831_10 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000000801 101.0
TH1_k127_5983831_11 - - - - 0.000000000000000000003713 98.0
TH1_k127_5983831_12 lactoylglutathione lyase activity - - - 0.000000000000004033 79.0
TH1_k127_5983831_2 May be involved in recombinational repair of damaged DNA K03631 GO:0000724,GO:0000725,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 516.0
TH1_k127_5983831_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 470.0
TH1_k127_5983831_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 299.0
TH1_k127_5983831_5 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002921 245.0
TH1_k127_5983831_6 Belongs to the CinA family K03743 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159 3.5.1.42 0.000000000000000000000000000000000000003097 149.0
TH1_k127_5983831_7 Thymidine phosphorylase - - - 0.0000000000000000000000000000000006419 147.0
TH1_k127_5983831_8 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000003183 131.0
TH1_k127_5983831_9 aspartyl protease K06985 - - 0.000000000000000000000000000005564 123.0
TH1_k127_6086909_0 Cytochrome d1, heme K15864 - 1.7.2.1,1.7.99.1 6.081e-299 924.0
TH1_k127_6086909_1 NapC/NirT cytochrome c family, N-terminal region K02569 - - 1.461e-216 687.0
TH1_k127_6086909_2 cytochrome d1, heme region K19345 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 556.0
TH1_k127_6086909_3 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000002728 203.0
TH1_k127_6086909_4 heme biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000007623 193.0
TH1_k127_6086909_5 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000002432 189.0
TH1_k127_6086909_6 transcriptional regulator AsnC family - - - 0.00000000000000000000000000000000000000000000003646 175.0
TH1_k127_6086909_7 Cupredoxin-like domain - - - 0.0000000000000000000000000000000005559 133.0
TH1_k127_6086909_8 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.000000000000000000000000002268 114.0
TH1_k127_6106341_0 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 591.0
TH1_k127_6106341_1 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 501.0
TH1_k127_6106341_2 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 414.0
TH1_k127_6106341_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 405.0
TH1_k127_6106341_4 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 372.0
TH1_k127_6106341_5 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000004046 262.0
TH1_k127_6106341_6 COG0241 Histidinol phosphatase and related phosphatases K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000001007 235.0
TH1_k127_6117260_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 402.0
TH1_k127_6117260_1 'Kef-type K transport - - - 0.000000000000000000000000000000000000000000000000000000000000000001792 236.0
TH1_k127_6117260_2 - - - - 0.0000000000000000000000000000000000461 138.0
TH1_k127_6117260_3 Putative regulatory protein - - - 0.00000000000000000000000000001097 121.0
TH1_k127_6117260_4 - - - - 0.0000000006215 63.0
TH1_k127_6117260_5 - - - - 0.000000001086 63.0
TH1_k127_6117501_0 Protein of unknown function, DUF255 K06888 - - 2.258e-226 721.0
TH1_k127_6117501_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 492.0
TH1_k127_6117501_2 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000005653 209.0
TH1_k127_6117501_3 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000000004923 171.0
TH1_k127_6117501_4 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000000008933 126.0
TH1_k127_6117501_5 - - - - 0.000000000000000000000000009176 109.0
TH1_k127_6117501_7 Sporulation and cell division repeat protein K03112 GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367 - 0.00000001317 64.0
TH1_k127_6117501_8 Cell division protein DamX K03112 GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367 - 0.000005522 55.0
TH1_k127_6126208_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 5.17e-205 654.0
TH1_k127_6126208_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 502.0
TH1_k127_6126208_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 292.0
TH1_k127_6126208_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000001305 177.0
TH1_k127_6126208_4 Ankyrin repeat - - - 0.000000000000000000000000000000000000000001258 172.0
TH1_k127_6152393_0 - - - - 3.058e-287 897.0
TH1_k127_6152393_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 562.0
TH1_k127_6152393_2 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 392.0
TH1_k127_6152393_3 PFAM protein phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 298.0
TH1_k127_6152393_4 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003765 253.0
TH1_k127_6163293_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 551.0
TH1_k127_6163293_1 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000004681 200.0
TH1_k127_6163293_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000006668 122.0
TH1_k127_6163293_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000002871 70.0
TH1_k127_6166725_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 465.0
TH1_k127_6166725_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004357 266.0
TH1_k127_6166725_2 Domain of unknown function (DUF4124) - - - 0.00000001946 62.0
TH1_k127_6200065_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 5.262e-281 875.0
TH1_k127_6200065_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 442.0
TH1_k127_6200065_10 NlpB/DapX lipoprotein K07287 - - 0.0000000000000000000000000006225 126.0
TH1_k127_6200065_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.00000000000000000001014 93.0
TH1_k127_6200065_2 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 417.0
TH1_k127_6200065_3 PFAM Radical SAM K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 417.0
TH1_k127_6200065_4 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 364.0
TH1_k127_6200065_5 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 350.0
TH1_k127_6200065_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003277 261.0
TH1_k127_6200065_7 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000005038 230.0
TH1_k127_6200065_8 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000002301 187.0
TH1_k127_6200065_9 SCP-2 sterol transfer family - - - 0.000000000000000000000000000008777 123.0
TH1_k127_6211696_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1410.0
TH1_k127_6211696_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 2.69e-200 636.0
TH1_k127_6211696_10 COG4240 Predicted kinase K15918 - 2.7.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001996 274.0
TH1_k127_6211696_11 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000137 265.0
TH1_k127_6211696_12 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000003011 216.0
TH1_k127_6211696_13 - - - - 0.00000000000000000000000000000000000000000000000000000000004282 209.0
TH1_k127_6211696_14 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000000000000001355 209.0
TH1_k127_6211696_15 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000005038 205.0
TH1_k127_6211696_16 Adenylate cyclase K05851 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.0000000000000000000000000000000000000000000000000000001428 222.0
TH1_k127_6211696_17 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000001152 181.0
TH1_k127_6211696_18 Four helix bundle sensory module for signal transduction K03406 - - 0.0000000000000000000000000000000000000006032 163.0
TH1_k127_6211696_19 F plasmid transfer operon, TraF, protein - - - 0.000000000000000000000000000000000000003945 161.0
TH1_k127_6211696_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 574.0
TH1_k127_6211696_20 RDD family - - - 0.00000000000000000000000000000000000002226 149.0
TH1_k127_6211696_21 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000000000000000000000000004141 123.0
TH1_k127_6211696_22 cheY-homologous receiver domain - - - 0.0000000000000000000000000005634 123.0
TH1_k127_6211696_23 ATP-binding region ATPase domain protein - - - 0.00000007318 63.0
TH1_k127_6211696_24 - - - - 0.000003665 57.0
TH1_k127_6211696_3 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 469.0
TH1_k127_6211696_4 6-phosphogluconate dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 446.0
TH1_k127_6211696_5 Major facilitator superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 405.0
TH1_k127_6211696_6 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 355.0
TH1_k127_6211696_7 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 345.0
TH1_k127_6211696_8 Permease YjgP YjgQ K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 334.0
TH1_k127_6211696_9 Permease YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006084 283.0
TH1_k127_6282168_0 Pyridine nucleotide-disulphide oxidoreductase K00362,K05297 - 1.18.1.1,1.7.1.15 0.0 1182.0
TH1_k127_6282168_1 Protein of unknown function (DUF4080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 582.0
TH1_k127_6282168_10 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964,K22130 - 4.1.1.104,4.2.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000005483 252.0
TH1_k127_6282168_11 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000002406 242.0
TH1_k127_6282168_12 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000008516 232.0
TH1_k127_6282168_13 Molecular chaperone - - - 0.0000000000000000000000000000000000000000001262 166.0
TH1_k127_6282168_14 - - - - 0.000000000000000000000000000000000000000005905 165.0
TH1_k127_6282168_15 Cobalamin (Vitamin B12) biosynthesis CbiX protein - - - 0.000000000000000000000000000000000000000007061 159.0
TH1_k127_6282168_16 TIGRFAM nitrite reductase NAD(P)H , small subunit K00363 - 1.7.1.15 0.0000000000000000000000000000000000000000082 155.0
TH1_k127_6282168_17 - - - - 0.0000000000000000000000000000000000000003389 151.0
TH1_k127_6282168_18 COG1278 Cold shock proteins K03704 - - 0.0000000000000000000000000007045 113.0
TH1_k127_6282168_19 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.0000000000000000000000003444 105.0
TH1_k127_6282168_2 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009692 426.0
TH1_k127_6282168_20 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000002468 94.0
TH1_k127_6282168_21 - - - - 0.000000000000008846 76.0
TH1_k127_6282168_22 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000008337 81.0
TH1_k127_6282168_23 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00004127 47.0
TH1_k127_6282168_3 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 420.0
TH1_k127_6282168_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 361.0
TH1_k127_6282168_5 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 364.0
TH1_k127_6282168_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 319.0
TH1_k127_6282168_7 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019509,GO:0019752,GO:0042578,GO:0043094,GO:0043102,GO:0043436,GO:0043874,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 284.0
TH1_k127_6282168_8 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004799 286.0
TH1_k127_6282168_9 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008201 266.0
TH1_k127_6282519_0 COG0520 Selenocysteine lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 287.0
TH1_k127_6282519_1 CYTH K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000002725 200.0
TH1_k127_6282519_2 kinase activity K07154 - 2.7.11.1 0.00000000000000000000000000000000000000000000002103 188.0
TH1_k127_6299157_0 PFAM Type II secretion system protein E K02454 - - 2.904e-206 653.0
TH1_k127_6299157_1 general secretion pathway protein D K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 616.0
TH1_k127_6299157_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002037 250.0
TH1_k127_6299157_3 General secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000002242 225.0
TH1_k127_6299157_4 General secretion pathway protein C K02452 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000459 137.0
TH1_k127_6299157_5 Belongs to the bacterial histone-like protein family - - - 0.0000000000000000000000000000001886 129.0
TH1_k127_6299157_6 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000000000008648 120.0
TH1_k127_6329723_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 579.0
TH1_k127_6329723_1 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 340.0
TH1_k127_6329723_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 331.0
TH1_k127_6329723_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 316.0
TH1_k127_6329723_4 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.0000000000000000000000000000000000000000000003909 171.0
TH1_k127_6329723_5 Sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000000336 136.0
TH1_k127_6329723_6 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.0008535 47.0
TH1_k127_6376765_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 547.0
TH1_k127_6376765_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 481.0
TH1_k127_6376765_10 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0000000000000003099 80.0
TH1_k127_6376765_11 response regulator K02488 - 2.7.7.65 0.0000000001363 72.0
TH1_k127_6376765_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 352.0
TH1_k127_6376765_3 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 299.0
TH1_k127_6376765_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000005094 236.0
TH1_k127_6376765_5 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000109 189.0
TH1_k127_6376765_6 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:0090499,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.1.85 0.000000000000000000000000000000000000000000000001379 184.0
TH1_k127_6376765_7 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - 0.0000000000000000000000000000000000000000000001068 171.0
TH1_k127_6376765_8 DsrC like protein K11179 - - 0.000000000000000000000003498 106.0
TH1_k127_6376765_9 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000006143 100.0
TH1_k127_6477848_0 AAA ATPase, central domain protein K07478 - - 1.452e-206 649.0
TH1_k127_6477848_1 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 333.0
TH1_k127_6477848_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000025 172.0
TH1_k127_6477848_3 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000007674 117.0
TH1_k127_6490143_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 454.0
TH1_k127_6490143_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 4.1.1.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 416.0
TH1_k127_6490143_2 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 344.0
TH1_k127_6490143_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 312.0
TH1_k127_6490143_4 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003234 274.0
TH1_k127_6490143_5 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008633 263.0
TH1_k127_6490143_6 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000000007101 218.0
TH1_k127_6490143_7 MafB19-like deaminase K01487 - 3.5.4.3 0.0000000000000000000000000000000000000000000000000001559 189.0
TH1_k127_6490143_8 STAS domain K20978 - - 0.000000000000000001188 89.0
TH1_k127_6498229_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 479.0
TH1_k127_6498229_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 379.0
TH1_k127_6498229_2 SMART AAA ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 374.0
TH1_k127_6498229_3 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 304.0
TH1_k127_6498229_4 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.000000000000000000000000000000000000000000000000000000000000000000001086 243.0
TH1_k127_6498229_5 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000002542 207.0
TH1_k127_6498229_6 cell envelope organization K05807,K08309 - - 0.000000000000000000000000000000000000000000000006677 188.0
TH1_k127_6498229_7 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000002582 129.0
TH1_k127_6498229_8 - - - - 0.000000000000000000000000000008112 123.0
TH1_k127_6498229_9 PEP-CTERM motif - - - 0.000000000002294 75.0
TH1_k127_6509986_0 Type II secretory pathway, component K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 464.0
TH1_k127_6509986_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002149 242.0
TH1_k127_6518846_0 inner membrane component K02011 - - 8.87e-231 726.0
TH1_k127_6518846_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 396.0
TH1_k127_6518846_2 extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 350.0
TH1_k127_6527358_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 511.0
TH1_k127_6527358_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 336.0
TH1_k127_6527358_2 von Willebrand factor type A domain - - - 0.0000000000000000000000000000000000000000000000012 192.0
TH1_k127_6533677_0 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15578 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000905 404.0
TH1_k127_6533677_1 Nitrate ABC transporter inner membrane subunit K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001107 258.0
TH1_k127_6533677_2 Belongs to the globin family - - - 0.0000000000000000000000000000000000000000000000000000002831 196.0
TH1_k127_6561597_0 long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 397.0
TH1_k127_6561597_1 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 361.0
TH1_k127_6561597_2 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001436 251.0
TH1_k127_6561597_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000002697 228.0
TH1_k127_6563632_0 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 332.0
TH1_k127_6563632_1 Protein of unknown function (DUF455) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 289.0
TH1_k127_6563632_2 protein conserved in bacteria K11022 - - 0.000000000000000000000000000000000000000001877 158.0
TH1_k127_6563632_3 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000001814 156.0
TH1_k127_6563632_4 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000002893 154.0
TH1_k127_6563632_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000008279 139.0
TH1_k127_6563632_6 - - - - 0.000000000000003716 78.0
TH1_k127_6571026_0 chondroitin AC lyase activity K00694,K01210,K03292 - 2.4.1.12,3.2.1.58 0.0 1084.0
TH1_k127_6571026_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.029e-286 896.0
TH1_k127_6571026_10 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008382 272.0
TH1_k127_6571026_11 Methyltransferase, chemotaxis proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001062 267.0
TH1_k127_6571026_12 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412,K13491 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000001566 259.0
TH1_k127_6571026_14 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000009192 228.0
TH1_k127_6571026_15 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000004278 206.0
TH1_k127_6571026_16 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000001042 197.0
TH1_k127_6571026_17 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000002471 183.0
TH1_k127_6571026_18 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000005006 181.0
TH1_k127_6571026_19 Two component signalling adaptor domain - - - 0.0000000000000000000000000000000000000000000000005049 183.0
TH1_k127_6571026_2 Molecular chaperone. Has ATPase activity K04079 - - 2.929e-284 884.0
TH1_k127_6571026_20 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000001148 172.0
TH1_k127_6571026_21 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000000001694 145.0
TH1_k127_6571026_22 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000002409 144.0
TH1_k127_6571026_23 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000966 125.0
TH1_k127_6571026_24 Belongs to the HSP15 family K04762 - - 0.0000000000000000000000000000001498 128.0
TH1_k127_6571026_25 Two component signalling adaptor domain K13488 - - 0.0000000000000000000000727 103.0
TH1_k127_6571026_26 FecR protein - - - 0.00000000000000000269 96.0
TH1_k127_6571026_27 PFAM FecR protein - - - 0.00000000000000709 84.0
TH1_k127_6571026_28 Late competence development protein ComFB - - - 0.0000000000000166 76.0
TH1_k127_6571026_29 Protein of unknown function (DUF3108) - - - 0.000000009377 65.0
TH1_k127_6571026_3 RESPONSE REGULATOR receiver K13490 - - 1.311e-221 717.0
TH1_k127_6571026_4 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 463.0
TH1_k127_6571026_5 Belongs to the RNA methyltransferase TrmD family K00554 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 344.0
TH1_k127_6571026_6 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K07315,K11444 - 2.7.7.65,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 332.0
TH1_k127_6571026_7 Methyl-accepting chemotaxis protein (MCP) signaling domain K13487 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 338.0
TH1_k127_6571026_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 328.0
TH1_k127_6571026_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002858 286.0
TH1_k127_6621644_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.545e-267 832.0
TH1_k127_6621644_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 499.0
TH1_k127_6621644_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000008997 214.0
TH1_k127_6621644_3 Histidine kinase - - - 0.0000000000000000000000000000000000009864 150.0
TH1_k127_6621644_4 Sporulation related domain - - - 0.000000000000000000000000000000005166 135.0
TH1_k127_6621644_5 Surface antigen - - - 0.000000000000000000000000001665 124.0
TH1_k127_6626810_0 Magnesium transport protein CorA - - - 2.455e-205 653.0
TH1_k127_6626810_1 Domain of unknown function (DUF1705) K03760,K19353 - 2.7.8.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 520.0
TH1_k127_6626810_10 subfamily IA, variant 3 K20881 - 3.1.3.5 0.0000000000000003482 78.0
TH1_k127_6626810_2 COG1194 A G-specific DNA glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 418.0
TH1_k127_6626810_3 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 328.0
TH1_k127_6626810_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000001583 230.0
TH1_k127_6626810_5 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000002373 201.0
TH1_k127_6626810_6 Copper resistance protein D - - - 0.00000000000000000000000000000000000000000000000000002043 194.0
TH1_k127_6626810_7 ATPase activity, coupled to transmembrane movement of substances - - - 0.00000000000000000000000000000000000000003411 155.0
TH1_k127_6626810_8 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000006491 141.0
TH1_k127_6626810_9 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000000005552 94.0
TH1_k127_6668760_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.221e-194 617.0
TH1_k127_6668760_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 482.0
TH1_k127_6668760_2 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 439.0
TH1_k127_6674023_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.6e-199 634.0
TH1_k127_6707939_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0 1131.0
TH1_k127_6707939_1 HlyD family secretion protein K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 565.0
TH1_k127_6707939_2 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K03778 - 1.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 426.0
TH1_k127_6707939_3 (ABC) transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 411.0
TH1_k127_6707939_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 374.0
TH1_k127_6707939_5 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 315.0
TH1_k127_6707939_6 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000000000000000000000005278 228.0
TH1_k127_673326_0 Sulfate transporter antisigma-factor antagonist STAS - - - 1.857e-236 741.0
TH1_k127_673326_1 Sigma-54 interaction domain - - - 8.105e-226 706.0
TH1_k127_673326_2 Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 503.0
TH1_k127_673326_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 486.0
TH1_k127_6771517_0 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 477.0
TH1_k127_6771517_1 Glyoxalase-like domain K07032 - - 0.00000000000000000000000000000000000000000000000000000000000000004051 226.0
TH1_k127_6821408_0 Peptidase, M16 K06972 - - 0.0 1266.0
TH1_k127_6821408_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.42e-266 831.0
TH1_k127_6821408_10 Protein of unknown function (DUF503) K09764 - - 0.00000000000000005552 83.0
TH1_k127_6821408_11 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.000000000000001053 79.0
TH1_k127_6821408_13 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000001523 69.0
TH1_k127_6821408_14 - - - - 0.000001171 52.0
TH1_k127_6821408_2 Belongs to the peptidase S16 family - - - 7.274e-220 707.0
TH1_k127_6821408_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 4.135e-207 651.0
TH1_k127_6821408_4 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 458.0
TH1_k127_6821408_5 Reduces the stability of FtsZ polymers in the presence of ATP K06916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 385.0
TH1_k127_6821408_6 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 374.0
TH1_k127_6821408_7 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000003676 236.0
TH1_k127_6821408_8 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000000000000000000000001264 161.0
TH1_k127_6821408_9 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000001109 98.0
TH1_k127_6824570_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.652e-229 716.0
TH1_k127_6824570_1 Ribosomal protein L11 methyltransferase K02687 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 331.0
TH1_k127_6824570_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000302 214.0
TH1_k127_6824570_3 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000000000000000000000000000006911 192.0
TH1_k127_6824570_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000000000000000000000118 184.0
TH1_k127_6824570_5 zinc-ribbon domain - - - 0.00000000000000000000000000000003305 138.0
TH1_k127_6824570_6 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.000000000000000007295 84.0
TH1_k127_6875695_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 373.0
TH1_k127_6875695_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000007123 265.0
TH1_k127_6875695_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000006577 220.0
TH1_k127_6875695_3 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000004701 160.0
TH1_k127_6875695_4 PFAM YicC-like - - - 0.0000000000000000000004741 98.0
TH1_k127_6907036_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 498.0
TH1_k127_6907036_1 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.000000000000000000000000000000000000000000000000000000000364 207.0
TH1_k127_6907036_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 0.000000000000000000000000000000000000000001318 158.0
TH1_k127_6907036_3 Cell division protein DamX K03112 GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367 - 0.00000000000000000000000000001281 135.0
TH1_k127_6942093_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 366.0
TH1_k127_6942093_1 PFAM Bacterial type II secretion system protein F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000004125 239.0
TH1_k127_6942093_2 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000008383 236.0
TH1_k127_6942093_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000002827 201.0
TH1_k127_6942093_4 - - - - 0.0000001897 53.0
TH1_k127_7005094_0 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 1.106e-213 684.0
TH1_k127_7005094_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 344.0
TH1_k127_7005094_10 - - - - 0.000000000000000000000000004076 116.0
TH1_k127_7005094_11 RNA-binding protein - - - 0.000000000000000000000008283 104.0
TH1_k127_7005094_12 peptidyl-tyrosine sulfation - - - 0.00000000000000001013 93.0
TH1_k127_7005094_13 FHA domain - - - 0.0000000000002127 81.0
TH1_k127_7005094_2 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 343.0
TH1_k127_7005094_3 PFAM MoeZ MoeB domain K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 316.0
TH1_k127_7005094_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 328.0
TH1_k127_7005094_5 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 320.0
TH1_k127_7005094_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003263 283.0
TH1_k127_7005094_7 Protein of unknown function (DUF3549) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004264 271.0
TH1_k127_7005094_8 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000002723 170.0
TH1_k127_7005094_9 - - - - 0.00000000000000000000000000000000000002034 153.0
TH1_k127_7013996_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.196e-293 908.0
TH1_k127_7013996_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 499.0
TH1_k127_7013996_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 322.0
TH1_k127_7013996_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000001513 158.0
TH1_k127_7013996_4 response to oxidative stress K03803 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000005854 107.0
TH1_k127_7013996_5 Domain of unknown function (DUF4845) - - - 0.000000000000000004422 88.0
TH1_k127_7013996_6 Glutaredoxin-like domain (DUF836) K00384 - 1.8.1.9 0.000000000000001662 78.0
TH1_k127_7013996_7 Sigma factor RpoE negative regulatory protein RseB K03598 - - 0.00002409 48.0
TH1_k127_70310_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.14e-322 997.0
TH1_k127_70310_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.316e-294 923.0
TH1_k127_70310_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 524.0
TH1_k127_70310_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000005382 218.0
TH1_k127_70310_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000002471 183.0
TH1_k127_70310_5 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000000000004139 183.0
TH1_k127_70310_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000001487 175.0
TH1_k127_70310_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000227 85.0
TH1_k127_7095420_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 8.418e-300 926.0
TH1_k127_7095420_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 9.619e-209 658.0
TH1_k127_7095420_10 - - - - 0.000000000000000000008409 93.0
TH1_k127_7095420_11 In Escherichia coli transcription of this gene is enhanced by polyamines K02914 - - 0.0000000000000004077 78.0
TH1_k127_7095420_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 559.0
TH1_k127_7095420_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 542.0
TH1_k127_7095420_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 452.0
TH1_k127_7095420_5 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 405.0
TH1_k127_7095420_6 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000306 280.0
TH1_k127_7095420_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000000000000000004078 117.0
TH1_k127_7095420_8 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.00000000000000000000001575 102.0
TH1_k127_7095420_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000000001884 98.0
TH1_k127_7136815_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 2.921e-196 614.0
TH1_k127_7136815_1 PhoH-like protein K06217 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 305.0
TH1_k127_7136815_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 GO:0006139,GO:0006351,GO:0006352,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010604,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031437,GO:0031439,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903311,GO:1903313,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000006286 200.0
TH1_k127_7136815_3 Belongs to the ompA family K21218 - - 0.00000000000000000000000000000000000000001553 164.0
TH1_k127_7152741_0 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 452.0
TH1_k127_7152741_1 Peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000001002 250.0
TH1_k127_7152741_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001985 247.0
TH1_k127_7152741_3 pfam nudix - - - 0.000000000000000000000000000000000000000000000000000000000000000000005174 239.0
TH1_k127_7152741_4 - - - - 0.0000000000000000000000000000000000464 137.0
TH1_k127_7152741_5 COG2214 DnaJ-class molecular chaperone - - - 0.000000000000000000000000000003892 125.0
TH1_k127_7152741_6 - - - - 0.00000000000004212 76.0
TH1_k127_7201635_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.4.2.14 5.443e-233 729.0
TH1_k127_7201635_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 612.0
TH1_k127_7201635_10 FlhB HrpN YscU SpaS Family K04061 - - 0.000000000000000000000000004073 113.0
TH1_k127_7201635_11 Tetratricopeptide repeat - - - 0.000000000000000000000006404 112.0
TH1_k127_7201635_12 Flagellar hook-length control protein FliK - - - 0.000000000000000000003118 107.0
TH1_k127_7201635_13 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000009817 96.0
TH1_k127_7201635_14 Flagellar biosynthesis protein, FliO - - - 0.00000000000000001573 90.0
TH1_k127_7201635_15 protein conserved in bacteria K03749 - - 0.0000000000002965 77.0
TH1_k127_7201635_16 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000009564 56.0
TH1_k127_7201635_2 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 463.0
TH1_k127_7201635_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 458.0
TH1_k127_7201635_4 PFAM Mur ligase middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 379.0
TH1_k127_7201635_5 Murein peptide amidase A K14054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 320.0
TH1_k127_7201635_6 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 321.0
TH1_k127_7201635_7 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 300.0
TH1_k127_7201635_8 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 - - 0.0000000000000000000000000000000000000000000002295 170.0
TH1_k127_7201635_9 Colicin v production K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.0000000000000000000000000000001325 130.0
TH1_k127_7241881_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1055.0
TH1_k127_7241881_1 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 432.0
TH1_k127_7247029_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1073.0
TH1_k127_7247029_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.096e-219 686.0
TH1_k127_7247029_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 564.0
TH1_k127_7247029_3 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 498.0
TH1_k127_7264657_0 Part of a membrane complex involved in electron transport K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 595.0
TH1_k127_7264657_1 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 306.0
TH1_k127_7264657_2 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 281.0
TH1_k127_7264657_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000001398 182.0
TH1_k127_7348911_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 477.0
TH1_k127_7348911_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 345.0
TH1_k127_7348911_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 357.0
TH1_k127_7348911_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009274 324.0
TH1_k127_7348911_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000002084 257.0
TH1_k127_7348911_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000002819 229.0
TH1_k127_7348911_6 Outer membrane lipoprotein LolB K02494 - - 0.000000000000000000000000000002217 128.0
TH1_k127_7351512_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 2.025e-199 634.0
TH1_k127_7351512_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 389.0
TH1_k127_7351512_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007832 250.0
TH1_k127_7351512_3 Histidine kinase K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000141 250.0
TH1_k127_7351512_4 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006808,GO:0008144,GO:0008150,GO:0009889,GO:0010565,GO:0017076,GO:0019216,GO:0019217,GO:0019222,GO:0030234,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042304,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0046890,GO:0050789,GO:0050790,GO:0050794,GO:0062012,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:0097367,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000002451 188.0
TH1_k127_7351512_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.000000000000000000000000000000000157 135.0
TH1_k127_7351512_6 RNA-binding protein - - - 0.0000000000000000000000000002367 117.0
TH1_k127_7351512_7 - K06950 - - 0.00000007044 56.0
TH1_k127_7390040_0 Ferrous iron transport protein B K04759 - - 1.822e-214 679.0
TH1_k127_7390040_1 PFAM Lytic transglycosylase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000009778 227.0
TH1_k127_7390040_2 cyclic nucleotide-binding K01420 - - 0.000000000000000000000000000000000000000000000000000000000009369 214.0
TH1_k127_7390040_3 Protein of unknown function (DUF2892) - - - 0.000000000000000000000008222 102.0
TH1_k127_7390040_4 PFAM PepSY-associated TM helix domain protein - - - 0.0000000000000000000002476 106.0
TH1_k127_7390040_5 FeoC like transcriptional regulator - - - 0.0000000000000000008601 92.0
TH1_k127_7411354_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 343.0
TH1_k127_7411354_1 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001558 269.0
TH1_k127_7411354_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000004701 171.0
TH1_k127_7411354_3 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000163 135.0
TH1_k127_7411354_4 COG0188 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), A subunit - - - 0.0000000000000000000000006435 106.0
TH1_k127_7411354_5 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family - - - 0.000000000000000000002766 96.0
TH1_k127_7411354_6 Nitroreductase family - - - 0.00000000002586 66.0
TH1_k127_7411354_7 EamA-like transporter family - - - 0.00000000003476 69.0
TH1_k127_7411354_8 - - - - 0.000006351 53.0
TH1_k127_7440379_0 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 437.0
TH1_k127_7440379_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 323.0
TH1_k127_7440379_2 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 287.0
TH1_k127_7440379_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000002321 231.0
TH1_k127_7440379_4 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000007858 202.0
TH1_k127_7492151_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 4.712e-197 621.0
TH1_k127_7492151_1 response regulator receiver K10126,K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 553.0
TH1_k127_7492151_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 442.0
TH1_k127_7492151_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 292.0
TH1_k127_7492151_4 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001182 275.0
TH1_k127_7492151_5 VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000001226 244.0
TH1_k127_7492151_6 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000033 153.0
TH1_k127_7492151_7 NUDIX domain K03574 - 3.6.1.55 0.0000000000002621 74.0
TH1_k127_7492151_8 protein containing LysM domain - - - 0.000000001239 70.0
TH1_k127_7492151_9 DNA-binding transcription factor activity - - - 0.0002368 47.0
TH1_k127_7644882_0 PFAM Peptidase family U32 K08303 - - 7.94e-225 700.0
TH1_k127_7644882_1 PFAM Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 351.0
TH1_k127_7644882_2 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000006644 260.0
TH1_k127_7644882_3 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000003539 250.0
TH1_k127_7644882_4 Phosphoglycerate mutase family K02226,K15634 - 3.1.3.73,5.4.2.12 0.0000000000000000000000000000000000000000000000000000003212 199.0
TH1_k127_7644882_5 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.1.10 0.000000000000000000000000000000000007816 147.0
TH1_k127_7644882_6 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.0000000000006263 73.0
TH1_k127_7655512_0 PFAM Spermine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 318.0
TH1_k127_7655512_1 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003823 260.0
TH1_k127_7655512_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001321 255.0
TH1_k127_7655512_3 oxidoreductase K06940 - - 0.00000000000000000000000000000000000000000000000000001365 190.0
TH1_k127_7741746_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 4.456e-321 998.0
TH1_k127_7741746_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 519.0
TH1_k127_7741746_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 452.0
TH1_k127_7741746_3 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.0000004852 53.0
TH1_k127_7764405_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 631.0
TH1_k127_7764405_1 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 479.0
TH1_k127_7764405_2 GGDEF domain K01768,K02488,K07676,K10715,K20976 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3,2.7.7.65,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 445.0
TH1_k127_7764405_3 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 387.0
TH1_k127_7764405_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 357.0
TH1_k127_7764405_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 296.0
TH1_k127_7764405_6 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003,K09810 - - 0.00000000000000000000000000000007777 125.0
TH1_k127_7764405_7 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000004825 115.0
TH1_k127_7795707_0 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 4.71e-238 756.0
TH1_k127_7795707_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 5.576e-195 624.0
TH1_k127_7795707_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 327.0
TH1_k127_7795707_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 301.0
TH1_k127_7795707_4 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002787 258.0
TH1_k127_7795707_5 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000003207 141.0
TH1_k127_7795707_6 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000001683 113.0
TH1_k127_7795707_7 Belongs to the UPF0434 family K09791 - - 0.000000000000003123 76.0
TH1_k127_7795707_8 Belongs to the Rsd AlgQ family K07740 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.000000006614 59.0
TH1_k127_7828341_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5,3.1.7.2 1.946e-253 801.0
TH1_k127_7828341_1 Major Facilitator Superfamily K19577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 384.0
TH1_k127_7828341_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000001041 108.0
TH1_k127_7828341_11 - - - - 0.0000001006 61.0
TH1_k127_7828341_2 Bacterial protein of unknown function (DUF898) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004004 274.0
TH1_k127_7828341_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001022 265.0
TH1_k127_7828341_4 2OG-Fe(II) oxygenase K07394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001448 244.0
TH1_k127_7828341_5 Uncharacterised protein family UPF0066 - GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000002345 221.0
TH1_k127_7828341_6 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000008474 212.0
TH1_k127_7828341_7 Uncharacterized protein conserved in bacteria (DUF2058) K09912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000006803 145.0
TH1_k127_7828341_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000001001 117.0
TH1_k127_7828341_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000004738 108.0
TH1_k127_7863627_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.873e-248 771.0
TH1_k127_7863627_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 301.0
TH1_k127_7863627_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000001041 241.0
TH1_k127_7882008_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1313.0
TH1_k127_7882008_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 598.0
TH1_k127_7882008_10 Flagellar protein YcgR - - - 0.00000000000000000000000007254 121.0
TH1_k127_7882008_11 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000003145 91.0
TH1_k127_7882008_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 503.0
TH1_k127_7882008_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 472.0
TH1_k127_7882008_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 367.0
TH1_k127_7882008_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000002015 199.0
TH1_k127_7882008_6 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000003306 147.0
TH1_k127_7882008_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000009185 148.0
TH1_k127_7882008_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000001094 141.0
TH1_k127_7882008_9 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000002823 110.0
TH1_k127_7907493_0 Likely ribonuclease with RNase H fold. K06959 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 1.137e-264 827.0
TH1_k127_7907493_1 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 432.0
TH1_k127_793319_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 413.0
TH1_k127_793319_1 general secretion pathway protein - - - 0.00004733 48.0
TH1_k127_7941351_0 Single-stranded-DNA-specific exonuclease K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 1.24e-204 653.0
TH1_k127_7941351_1 Protein conserved in bacteria - - - 0.000000000000000000000000000001475 128.0
TH1_k127_7950431_0 PFAM FAD dependent oxidoreductase K00116 - 1.1.5.4 8.559e-218 683.0
TH1_k127_7950431_1 Diguanylate cyclase - - - 1.506e-212 692.0
TH1_k127_7950431_10 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 361.0
TH1_k127_7950431_11 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 342.0
TH1_k127_7950431_12 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 343.0
TH1_k127_7950431_13 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 329.0
TH1_k127_7950431_14 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 321.0
TH1_k127_7950431_15 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 293.0
TH1_k127_7950431_16 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002003 264.0
TH1_k127_7950431_17 carbonic - - - 0.00000000000000000000000000000000000000000000000000000000000000001727 228.0
TH1_k127_7950431_18 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000006468 215.0
TH1_k127_7950431_19 Competence protein - - - 0.0000000000000000000000000000000000000000000000000000000004872 209.0
TH1_k127_7950431_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 1.358e-207 655.0
TH1_k127_7950431_20 Elongation factor P (EF-P) OB domain K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000002353 196.0
TH1_k127_7950431_21 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.00000000000000000000000000000000000000000000000000002575 191.0
TH1_k127_7950431_22 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000694 190.0
TH1_k127_7950431_23 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000002524 194.0
TH1_k127_7950431_24 Phosphoribosyl-ATP pyrophosphohydrolase - - - 0.0000000000000000000000000000000000000000000000004759 178.0
TH1_k127_7950431_25 Dihaem cytochrome c - - - 0.00000000000000000000000000000000000000000000003423 174.0
TH1_k127_7950431_26 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000001106 174.0
TH1_k127_7950431_27 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000000000000000000000002002 168.0
TH1_k127_7950431_28 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000002919 170.0
TH1_k127_7950431_29 metal cluster binding K06940 - - 0.000000000000000000000000000000000000000002609 158.0
TH1_k127_7950431_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 607.0
TH1_k127_7950431_30 Disulfide bond formation protein DsbB - - - 0.00000000000000000000000000000000000000129 153.0
TH1_k127_7950431_31 - - - - 0.00000000000000000000000000000001681 131.0
TH1_k127_7950431_32 Cold shock K03704 - - 0.000000000000000000000000008483 111.0
TH1_k127_7950431_33 Protein of unknown function (DUF2914) - - - 0.00000000000000000000000007913 113.0
TH1_k127_7950431_34 Tetratricopeptide repeat - - - 0.000000000000000000000002659 108.0
TH1_k127_7950431_35 - - - - 0.0000000006756 61.0
TH1_k127_7950431_36 - - - - 0.00008558 47.0
TH1_k127_7950431_38 - - - - 0.0001959 47.0
TH1_k127_7950431_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 545.0
TH1_k127_7950431_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 492.0
TH1_k127_7950431_6 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 485.0
TH1_k127_7950431_7 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 470.0
TH1_k127_7950431_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 435.0
TH1_k127_7950431_9 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 397.0
TH1_k127_801173_0 COG2925 Exonuclease I K01141 GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 3.1.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 559.0
TH1_k127_801173_1 PFAM Glycosyl transferase, family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 394.0
TH1_k127_801173_2 PFAM periplasmic solute binding protein K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 338.0
TH1_k127_801173_3 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009797 279.0
TH1_k127_801173_4 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001418 267.0
TH1_k127_801173_5 phosphate-selective porin O and P - - - 0.000000000000000000001602 95.0
TH1_k127_801173_6 Resolvase, N terminal domain - - - 0.0000005972 53.0
TH1_k127_801173_7 - - - - 0.000008518 51.0
TH1_k127_8032844_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 3.49e-279 864.0
TH1_k127_8032844_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.76e-264 821.0
TH1_k127_8032844_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 429.0
TH1_k127_8032844_3 Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000002017 248.0
TH1_k127_8032844_4 Cytochrome c oxidase subunit III K02164,K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000001212 238.0
TH1_k127_8032844_6 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000009073 164.0
TH1_k127_8032844_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0002817 44.0
TH1_k127_8040337_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 304.0
TH1_k127_8040337_1 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000009222 168.0
TH1_k127_8072161_0 PFAM Binding-protein-dependent transport systems inner membrane component K02037 - - 5.693e-216 692.0
TH1_k127_8072161_1 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 488.0
TH1_k127_8072161_2 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000002318 169.0
TH1_k127_8072161_3 Histidine kinase - - - 0.00000000000000000000001151 104.0
TH1_k127_8082886_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.848e-238 760.0
TH1_k127_8082886_1 Nadh flavin oxidoreductase nadh oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 595.0
TH1_k127_8082886_2 PFAM Fructosamine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 367.0
TH1_k127_8082886_3 protein domain (DUF2202) - - - 0.0000000000000000000000000000000000000000000000000000000004554 211.0
TH1_k127_8082886_4 Belongs to the ompA family K03286 - - 0.000000000000000000008789 98.0
TH1_k127_8082886_5 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000005584 70.0
TH1_k127_8214666_0 FAD binding domain K00394 - 1.8.99.2 1.134e-232 722.0
TH1_k127_8214666_1 Galactose-1-phosphate uridyl transferase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 565.0
TH1_k127_8214666_2 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 300.0
TH1_k127_8214666_3 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000000003405 203.0
TH1_k127_8220487_0 catalyzes a condensation reaction in fatty acid biosynthesis addition of an acyl acceptor of two carbons from malonyl-ACP K00647 - 2.3.1.41 7.046e-201 631.0
TH1_k127_8220487_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 403.0
TH1_k127_8220487_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 362.0
TH1_k127_8220487_3 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 305.0
TH1_k127_8220487_4 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001827 291.0
TH1_k127_8220487_5 Domain of unknown function (DUF4426) - - - 0.0000000000000000000000000001563 120.0
TH1_k127_8236810_0 PFAM Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000101 282.0
TH1_k127_8236810_1 Sigma factor PP2C-like phosphatases K01079 - 3.1.3.3 0.00000000000000000002748 98.0
TH1_k127_8236810_2 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.000000002076 58.0
TH1_k127_8268395_0 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.0 1132.0
TH1_k127_8268395_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.028e-260 808.0
TH1_k127_8268395_10 conserved protein - - - 0.000000000000000000000000001316 114.0
TH1_k127_8268395_11 chemotaxis signal transduction protein K06598 - - 0.00000000000000000007599 94.0
TH1_k127_8268395_12 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000003947 70.0
TH1_k127_8268395_2 chemotaxis K02660 - - 4.556e-218 697.0
TH1_k127_8268395_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 2.761e-202 634.0
TH1_k127_8268395_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 567.0
TH1_k127_8268395_5 reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 380.0
TH1_k127_8268395_6 response regulator receiver K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000000003753 230.0
TH1_k127_8268395_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000001646 223.0
TH1_k127_8268395_8 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000008123 188.0
TH1_k127_8268395_9 Two component signalling adaptor domain K02659 - - 0.0000000000000000000000000000000000000004897 154.0
TH1_k127_8354285_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 592.0
TH1_k127_8354285_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 520.0
TH1_k127_8354285_2 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 421.0
TH1_k127_8354285_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 400.0
TH1_k127_8354285_4 Iron--sulfur cluster insertion protein erpA K15724 - - 0.000000000000000000000000000000000000000000000000000000001932 201.0
TH1_k127_8354285_5 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000001015 155.0
TH1_k127_8354285_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.0000000000000000000000000001105 115.0
TH1_k127_8354285_7 - - - - 0.0000000000000000000000001681 115.0
TH1_k127_8389608_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 471.0
TH1_k127_8389608_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000008403 209.0
TH1_k127_8389608_2 TIGRFAM type IV pilus secretin (or competence protein) PilQ K02666 - - 0.000000000000000000000000004501 111.0
TH1_k127_8389608_3 PFAM Ig domain protein, group 1 domain protein - - - 0.00001451 55.0
TH1_k127_8396973_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 385.0
TH1_k127_8396973_1 PFAM sigma-54 factor interaction domain-containing protein K06714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 373.0
TH1_k127_8396973_2 DNA integration K03733 GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 314.0
TH1_k127_8396973_3 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000002028 132.0
TH1_k127_8396973_4 Proteasome subunit K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.00000000000000000000000000001616 118.0
TH1_k127_8396973_5 PFAM MarR family - - - 0.00001542 50.0
TH1_k127_8475081_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1019.0
TH1_k127_8511187_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 5.649e-228 719.0
TH1_k127_8511187_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000001593 214.0
TH1_k127_8553207_0 GTP-binding protein TypA K06207 - - 1.083e-294 914.0
TH1_k127_8553207_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 4.152e-218 693.0
TH1_k127_8553207_2 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 588.0
TH1_k127_8553207_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 379.0
TH1_k127_8553207_4 COG2183 Transcriptional accessory protein K06959 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001788 271.0
TH1_k127_8553207_5 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005428 259.0
TH1_k127_8553207_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000003874 224.0
TH1_k127_8553207_7 PFAM globin K06886 - - 0.00000000000000000000000000000000000000000000000001746 181.0
TH1_k127_8553207_8 Protein of unknown function (DUF1631) - - - 0.00000000000000000000000000000000001508 152.0
TH1_k127_8560322_0 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 313.0
TH1_k127_8560322_1 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000001964 201.0
TH1_k127_8560322_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000008397 158.0
TH1_k127_8560322_3 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.0000000000000000000001529 102.0
TH1_k127_8561762_0 PFAM Lytic K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 424.0
TH1_k127_8561762_1 Sel1-like repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002726 265.0
TH1_k127_8561762_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008383 249.0
TH1_k127_8561762_3 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000004717 235.0
TH1_k127_8561762_4 - - - - 0.000000000000000000000000000000000000000000007735 171.0
TH1_k127_8561762_5 Thioredoxin - - - 0.000000000000000000000000000000000001439 141.0
TH1_k127_8561762_6 - - - - 0.00000000000000000000000000000000001768 147.0
TH1_k127_8569976_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 466.0
TH1_k127_8569976_1 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 354.0
TH1_k127_8569976_2 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000000726 134.0
TH1_k127_858714_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 4.202e-225 706.0
TH1_k127_858714_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 481.0
TH1_k127_858714_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 407.0
TH1_k127_858714_3 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 344.0
TH1_k127_858714_4 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 325.0
TH1_k127_858714_5 Cytochrome c - - - 0.00000000000000000000000005767 111.0
TH1_k127_858714_6 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000006742 103.0
TH1_k127_8619462_0 DNA polymerase III, alpha subunit K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 493.0
TH1_k127_8619462_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 429.0
TH1_k127_8660095_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.348e-267 852.0
TH1_k127_8660095_1 Diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 423.0
TH1_k127_8660095_2 Metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 295.0
TH1_k127_8660095_3 OsmC-like protein K06889,K07397 - - 0.00000000000000000000000000000000000000000000000000000008982 205.0
TH1_k127_8660095_4 aspartyl protease K06985 - - 0.0000000000000000000000000000000000000001593 156.0
TH1_k127_8660095_5 - - - - 0.000000000000000004696 85.0
TH1_k127_8694106_0 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 548.0
TH1_k127_8694106_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 442.0
TH1_k127_8694106_2 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 419.0
TH1_k127_8706096_0 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 373.0
TH1_k127_8706096_1 Crp-like helix-turn-helix domain K21563 - - 0.000000000000000000000000000000000000000000000000000001663 199.0
TH1_k127_8706096_2 COG2940 Proteins containing SET domain K07117 - - 0.00000000000000000000000007932 111.0
TH1_k127_8735629_0 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 441.0
TH1_k127_8735629_1 Gram-negative porin - - - 0.000000000000000000001664 103.0
TH1_k127_8735629_2 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000004001 92.0
TH1_k127_8761652_0 Domain of unknown function (DUF4478) K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 385.0
TH1_k127_8761652_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 362.0
TH1_k127_8761652_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03214 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000003364 260.0
TH1_k127_8761652_3 Membrane - - - 0.0000000000000000000002454 104.0
TH1_k127_8761652_4 COG2826 Transposase and inactivated derivatives, IS30 family K07482 - - 0.000000000005379 65.0
TH1_k127_877481_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 5.315e-276 856.0
TH1_k127_877481_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 1.995e-202 638.0
TH1_k127_877481_2 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 328.0
TH1_k127_877481_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000009827 263.0
TH1_k127_877481_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000157 135.0
TH1_k127_8812082_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 1.202e-243 759.0
TH1_k127_8812082_1 metal ion transport K14445 - - 2.796e-218 687.0
TH1_k127_8812082_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 448.0
TH1_k127_8812082_3 Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 434.0
TH1_k127_8812082_4 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 320.0
TH1_k127_8812082_5 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000007244 189.0
TH1_k127_8812082_6 IMP dehydrogenase activity K06041,K11527 - 2.7.13.3,5.3.1.13 0.0000000008269 66.0
TH1_k127_881499_0 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 453.0
TH1_k127_881499_1 FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 393.0
TH1_k127_881499_2 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 373.0
TH1_k127_881499_3 PFAM Fe-S metabolism associated K02426 - - 0.000000000000000000000000000000000000000000000000000000002734 203.0
TH1_k127_881499_4 Belongs to the HesB IscA family K05997,K13628 - - 0.00000000000000000000000000000000000000000001639 164.0
TH1_k127_881499_5 FeS assembly SUF system protein - - - 0.00000000000000000000000000000000002819 138.0
TH1_k127_8829461_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 6.701e-220 688.0
TH1_k127_8829461_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 518.0
TH1_k127_8829461_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 487.0
TH1_k127_8829461_3 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 374.0
TH1_k127_8829461_4 HflC and HflK could regulate a protease K04087 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 338.0
TH1_k127_8829461_5 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002115 273.0
TH1_k127_8829461_6 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000007507 72.0
TH1_k127_8829461_7 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000001866 68.0
TH1_k127_886630_0 UPF0313 protein - - - 0.0 1177.0
TH1_k127_886630_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 6.677e-290 904.0
TH1_k127_886630_10 COG1108 ABC-type Mn2 Zn2 transport systems permease components K09816 GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002714 264.0
TH1_k127_886630_11 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000001842 199.0
TH1_k127_886630_12 ABC-type Zn2 transport system, periplasmic component surface adhesin K09815 - - 0.00000000000000000000000000000000000000000000000000008217 197.0
TH1_k127_886630_13 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000002647 178.0
TH1_k127_886630_14 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000004389 179.0
TH1_k127_886630_19 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000003779 53.0
TH1_k127_886630_2 sulphate transporter K03321 - - 2.833e-249 782.0
TH1_k127_886630_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07713 GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 615.0
TH1_k127_886630_4 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 562.0
TH1_k127_886630_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 364.0
TH1_k127_886630_6 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 333.0
TH1_k127_886630_7 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 319.0
TH1_k127_886630_8 COG0501 Zn-dependent protease with chaperone function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 314.0
TH1_k127_886630_9 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 309.0
TH1_k127_8896819_0 Heat shock 70 kDa protein K04043 - - 0.0 1004.0
TH1_k127_8896819_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.01e-197 622.0
TH1_k127_8896819_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000001859 188.0
TH1_k127_8896819_11 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000001537 149.0
TH1_k127_8896819_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000003927 138.0
TH1_k127_8896819_13 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000002741 96.0
TH1_k127_8896819_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 560.0
TH1_k127_8896819_3 Anthranilate synthase component I K01657,K01665 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 499.0
TH1_k127_8896819_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 379.0
TH1_k127_8896819_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 379.0
TH1_k127_8896819_6 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 351.0
TH1_k127_8896819_7 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 342.0
TH1_k127_8896819_8 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000004953 255.0
TH1_k127_8896819_9 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000008167 210.0
TH1_k127_8918907_0 cation transport ATPase K01533 - 3.6.3.4 3.268e-302 943.0
TH1_k127_8918907_1 Sulfate permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 438.0
TH1_k127_8918907_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 332.0
TH1_k127_8918907_3 cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000000006976 79.0
TH1_k127_8943055_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 441.0
TH1_k127_8943055_1 LemA Family K03744 - - 0.000000000000000000000000000000000000004957 147.0
TH1_k127_8946651_0 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 319.0
TH1_k127_8946651_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000004301 139.0
TH1_k127_8946651_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000002164 89.0
TH1_k127_8950059_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 515.0
TH1_k127_8950059_1 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 355.0
TH1_k127_8950059_2 Flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007868 278.0
TH1_k127_8950059_3 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000131 271.0
TH1_k127_8950059_4 DJ-1/PfpI family K03152 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009100,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019538,GO:0022613,GO:0030091,GO:0033554,GO:0034599,GO:0036211,GO:0036524,GO:0036525,GO:0042026,GO:0042221,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000001586 231.0
TH1_k127_8950059_5 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000003179 192.0
TH1_k127_8950059_6 COG0526 Thiol-disulfide isomerase and thioredoxins K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000005283 190.0
TH1_k127_8950059_7 regulatory protein, arsR - - - 0.000000000000000000000000000000000000000000001097 167.0
TH1_k127_8950059_8 PFAM Rhodanese-like K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000002444 141.0
TH1_k127_8950059_9 Cyclic nucleotide-monophosphate binding domain K01420 - - 0.0000000000000000000000000006545 122.0
TH1_k127_9025594_0 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000001518 239.0
TH1_k127_9025594_1 PFAM Pentapeptide - - - 0.00000000000000000000000001361 119.0
TH1_k127_9025594_2 Glutaredoxin - - - 0.0000000000002844 74.0
TH1_k127_9074512_0 FAD linked - - - 0.0 1794.0
TH1_k127_9074512_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 7.917e-232 729.0
TH1_k127_9074512_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 318.0
TH1_k127_9074512_3 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001591 280.0
TH1_k127_9074512_4 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001854 242.0
TH1_k127_9074512_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.00000000000000000000000000000000000000000000000001871 185.0
TH1_k127_9074512_6 COG3203 Outer membrane protein (porin) - - - 0.0000000000000000000000000000000000000009747 158.0
TH1_k127_9074512_7 Belongs to the UPF0149 family K09895 - - 0.0000000000000000000000000000000003082 139.0
TH1_k127_9074512_8 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000006683 96.0
TH1_k127_9074512_9 - - - - 0.00003243 50.0
TH1_k127_9155846_0 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 2.226e-251 782.0
TH1_k127_9155846_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 599.0
TH1_k127_9155846_2 Type III effector Hrp-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 595.0
TH1_k127_9155846_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 558.0
TH1_k127_9155846_4 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 540.0
TH1_k127_9155846_5 PFAM FAD linked oxidase domain protein K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 411.0
TH1_k127_9155846_6 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 357.0
TH1_k127_9155846_7 PFAM Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 307.0
TH1_k127_9155846_8 PAS domain - - - 0.000000000000000000004757 95.0
TH1_k127_9155846_9 PFAM VanZ - - - 0.0002323 49.0
TH1_k127_9173811_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 438.0
TH1_k127_9173811_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 359.0
TH1_k127_9173811_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 315.0
TH1_k127_9247961_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.046e-238 748.0
TH1_k127_9247961_1 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 608.0
TH1_k127_9247961_10 Subunit R is required for both nuclease and ATPase activities, but not for modification - - - 0.00000001764 61.0
TH1_k127_9247961_11 Subunit R is required for both nuclease and ATPase activities, but not for modification - - - 0.000004811 54.0
TH1_k127_9247961_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 501.0
TH1_k127_9247961_3 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000192 275.0
TH1_k127_9247961_4 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005184 267.0
TH1_k127_9247961_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003083 236.0
TH1_k127_9247961_6 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000002376 199.0
TH1_k127_9247961_7 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.000000000000000000000000000000000001287 145.0
TH1_k127_9247961_8 response regulator receiver K02658 - - 0.000000000000000000000000000000000005604 142.0
TH1_k127_9247961_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000002004 136.0
TH1_k127_9249430_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 534.0
TH1_k127_9249430_1 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004352 253.0
TH1_k127_9249430_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000002602 243.0
TH1_k127_9249430_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000008381 216.0
TH1_k127_9249430_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000006326 190.0
TH1_k127_9249430_5 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000000004066 162.0
TH1_k127_9249430_6 Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000003411 158.0
TH1_k127_9249430_7 NTP pyrophosphohydrolases including oxidative damage repair enzymes K08310 - 3.6.1.67 0.00000000000000000002845 92.0
TH1_k127_9249430_8 Membrane protein involved in colicin uptake K03646 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0016032,GO:0017038,GO:0019058,GO:0019904,GO:0030260,GO:0031224,GO:0031226,GO:0032153,GO:0033036,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046677,GO:0046678,GO:0046718,GO:0046790,GO:0050896,GO:0051179,GO:0051234,GO:0051301,GO:0051701,GO:0051704,GO:0051716,GO:0051806,GO:0051828,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:0071944,GO:0097718,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - 0.00004373 53.0
TH1_k127_9294869_0 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 301.0
TH1_k127_9294869_1 - - - - 0.0000000000000000000000009624 109.0
TH1_k127_9294869_3 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.0002482 51.0
TH1_k127_9314215_0 acyl-CoA dehydrogenase K06445 - - 2.134e-287 904.0
TH1_k127_9314215_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 555.0
TH1_k127_9314215_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 434.0
TH1_k127_9314215_3 PFAM 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 332.0
TH1_k127_9314215_4 PFAM Adenylate cyclase K01768 - 4.6.1.1 0.00000002354 57.0
TH1_k127_9336143_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0044237 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 601.0
TH1_k127_9336143_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 424.0
TH1_k127_9336143_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 398.0
TH1_k127_9336143_3 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000000000000000003158 114.0
TH1_k127_9343752_0 TIGRFAM general secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000001481 227.0
TH1_k127_9343752_1 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000002357 215.0
TH1_k127_9343752_2 general secretion pathway protein K02456 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000001083 193.0
TH1_k127_9343752_3 General secretion pathway protein J K02459 - - 0.000000000000000000000000000000000001188 147.0
TH1_k127_9343752_4 membrane protein (homolog of Drosophila rhomboid) - - - 0.0000000000000000000000000000000007399 137.0
TH1_k127_9343752_5 GspL periplasmic domain - - - 0.0000000000000000000002322 106.0
TH1_k127_9343752_6 general secretion pathway protein K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000008787 74.0
TH1_k127_9343752_7 COG2165 Type II secretory pathway, pseudopilin PulG K02457 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000002111 68.0
TH1_k127_939477_0 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 468.0
TH1_k127_939477_1 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 313.0
TH1_k127_9411149_0 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 392.0
TH1_k127_9411149_1 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.00000000000000001435 89.0
TH1_k127_9424110_0 Type II secretory pathway component ExeA K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 443.0
TH1_k127_9424110_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000002242 221.0
TH1_k127_9424110_2 COG0784 FOG CheY-like receiver K02658 - - 0.00000000000000000000000000000000000000000298 158.0
TH1_k127_9424110_3 Type II secretion system protein B K02451 - - 0.0000000000000000000008251 103.0
TH1_k127_9449290_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 519.0
TH1_k127_9449290_1 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 476.0
TH1_k127_9449290_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 337.0
TH1_k127_9449290_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000003644 214.0
TH1_k127_9449290_4 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000002041 209.0
TH1_k127_9449290_5 COG1145 Ferredoxin - - - 0.000000000000000000000000000000000000000000007671 163.0
TH1_k127_9449290_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000007478 58.0