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Overview

ID MAG03871
Name TH1_bin.47
Sample SMP0100
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus Aquabacterium
Species
Assembly information
Completeness (%) 91.92
Contamination (%) 2.12
GC content (%) 64.0
N50 (bp) 4,011
Genome size (bp) 3,329,540

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3416

Gene name Description KEGG GOs EC E-value Score Sequence
TH1_k127_1001975_0 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 391.0
TH1_k127_1001975_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 376.0
TH1_k127_100268_0 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 4.393e-280 872.0
TH1_k127_100268_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 447.0
TH1_k127_100268_2 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 432.0
TH1_k127_100268_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002499 255.0
TH1_k127_1045538_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 463.0
TH1_k127_1045538_1 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000005866 224.0
TH1_k127_1045538_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000000000000000003234 204.0
TH1_k127_104891_0 GMC family oxidoreductase - - - 1.032e-238 741.0
TH1_k127_104891_1 protein-glutamate methylesterase activity K03412,K03413,K13924 - 2.1.1.80,3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 306.0
TH1_k127_1057575_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.638e-231 721.0
TH1_k127_1057575_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 443.0
TH1_k127_1057575_2 Type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 291.0
TH1_k127_1057575_3 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000000000000000000003561 165.0
TH1_k127_1058542_0 PFAM General secretion pathway protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 314.0
TH1_k127_1058542_1 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003325 241.0
TH1_k127_1058542_2 Prokaryotic N-terminal methylation motif K02459 - - 0.0000000000000000000000000000000000000000000000000000000000000001611 228.0
TH1_k127_1058542_3 general secretion pathway protein K02458 - - 0.00000000000000000000000000000000000000000001588 166.0
TH1_k127_1058542_4 Prokaryotic N-terminal methylation motif K02457 - - 0.000000000000000000000000000000009664 134.0
TH1_k127_1058542_5 general secretion pathway protein K02452 - - 0.0002447 53.0
TH1_k127_1061509_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000001032 236.0
TH1_k127_1061509_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000334 231.0
TH1_k127_1061509_2 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000001939 200.0
TH1_k127_1061509_3 response regulator - - - 0.000000000000001657 81.0
TH1_k127_1066602_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 518.0
TH1_k127_1066602_1 Regulator K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 386.0
TH1_k127_1066602_2 Peptidase family M3 K01414 - 3.4.24.70 0.000000000000000000000000000000000000000000000000000000000001685 213.0
TH1_k127_1073885_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 1.147e-238 743.0
TH1_k127_1073885_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 303.0
TH1_k127_1080412_0 Cobalamin synthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 588.0
TH1_k127_1080412_1 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 413.0
TH1_k127_1080412_2 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 312.0
TH1_k127_1080412_3 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005959 264.0
TH1_k127_1089249_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 533.0
TH1_k127_1091926_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 282.0
TH1_k127_1091926_1 - - - - 0.00000000000000000000000000000000001027 143.0
TH1_k127_1091926_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000001025 133.0
TH1_k127_109429_0 - - - - 0.00000000000000000000000000000000000006889 154.0
TH1_k127_1095275_0 GMC oxidoreductase - - - 1.574e-207 696.0
TH1_k127_1095275_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 291.0
TH1_k127_1099161_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 379.0
TH1_k127_1099161_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 303.0
TH1_k127_1105102_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 301.0
TH1_k127_1105102_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 307.0
TH1_k127_1105102_2 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000006805 207.0
TH1_k127_1105102_3 SEFIR domain - - - 0.000000000000000000000000000000000000000000000000001297 186.0
TH1_k127_1106532_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 591.0
TH1_k127_1106532_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 437.0
TH1_k127_1142942_0 Biotin carboxylase C-terminal domain K13777 - 6.4.1.5 7.697e-316 977.0
TH1_k127_1142942_1 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 2.589e-227 707.0
TH1_k127_1142942_2 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 541.0
TH1_k127_1142942_3 Enoyl-CoA hydratase/isomerase K13779 - 4.2.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 367.0
TH1_k127_1142942_4 DEAD-like helicases superfamily K07012 - - 0.00001663 48.0
TH1_k127_1143774_0 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 9.714e-310 949.0
TH1_k127_1143774_1 TIGRFAM nitrogen regulation protein NR(I) K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 1.492e-261 813.0
TH1_k127_1143774_2 General secretory system II, protein E domain protein K02454,K02652 - - 2.065e-209 668.0
TH1_k127_1143774_3 Histidine kinase K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 591.0
TH1_k127_1143774_4 Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 482.0
TH1_k127_1143774_5 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 429.0
TH1_k127_1143774_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 284.0
TH1_k127_1143774_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006697 245.0
TH1_k127_1143774_8 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001653 232.0
TH1_k127_1143774_9 - - - - 0.000000000000000000000000000000000000000000007825 169.0
TH1_k127_1150492_0 Phosphotransferase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 487.0
TH1_k127_1150492_1 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003896 276.0
TH1_k127_1150492_2 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000127 64.0
TH1_k127_1152378_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0 1271.0
TH1_k127_1152378_1 Belongs to the thiolase family K00626 - 2.3.1.9 4.949e-240 744.0
TH1_k127_1152378_2 Acyl-CoA dehydrogenase, C-terminal domain K00249,K00255 - 1.3.8.7,1.3.8.8 2.118e-234 728.0
TH1_k127_1152378_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 325.0
TH1_k127_1152378_4 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 302.0
TH1_k127_1152378_5 Belongs to the DEAD box helicase family - - - 0.00000000000000000000000001321 111.0
TH1_k127_1152800_0 Transcriptional regulator K13635 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 550.0
TH1_k127_1152800_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000001911 207.0
TH1_k127_1166941_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 571.0
TH1_k127_1166941_1 epimerase dehydratase K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 493.0
TH1_k127_1166941_2 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 454.0
TH1_k127_1166941_3 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 416.0
TH1_k127_1166941_4 Heavy-metal resistance - - - 0.000000000000000000000005064 111.0
TH1_k127_1173343_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 375.0
TH1_k127_1173343_1 general secretion pathway protein K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006486 242.0
TH1_k127_1184641_0 PFAM Orn Lys Arg decarboxylase K01584 - 4.1.1.19 0.0 1225.0
TH1_k127_1184641_1 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 462.0
TH1_k127_1184641_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 369.0
TH1_k127_1207364_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 371.0
TH1_k127_1207364_1 PFAM Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 338.0
TH1_k127_1207364_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 297.0
TH1_k127_1207364_3 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000001345 177.0
TH1_k127_1207364_4 Sulfurtransferase - - - 0.00000000000000000000000004682 108.0
TH1_k127_1215995_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 1.943e-271 844.0
TH1_k127_1215995_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 591.0
TH1_k127_1215995_2 Pfam:HipA_N K07154 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 504.0
TH1_k127_1215995_3 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 385.0
TH1_k127_1215995_4 Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 291.0
TH1_k127_1215995_5 transcriptional regulators - - - 0.000000000000000000000000000000002061 132.0
TH1_k127_1215995_6 Domain of Unknown Function (DUF350) - - - 0.0000000000000000000000000000002156 126.0
TH1_k127_1215995_7 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000001505 109.0
TH1_k127_1215995_8 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000001177 74.0
TH1_k127_1221200_0 Helicase K03657 - 3.6.4.12 3e-203 636.0
TH1_k127_1240343_0 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000006334 246.0
TH1_k127_1240343_1 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000006944 106.0
TH1_k127_1240343_2 probably involved in intracellular septation K06190 - - 0.0000000000001063 71.0
TH1_k127_1250933_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 584.0
TH1_k127_1250996_0 4Fe-4S dicluster domain K11473 - - 1.666e-198 631.0
TH1_k127_1250996_1 PFAM FAD linked oxidase domain protein K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 464.0
TH1_k127_1250996_2 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001088 273.0
TH1_k127_1250996_3 cellulase activity - - - 0.0000000000000000000000000000000000000000008727 174.0
TH1_k127_1250996_4 Dienelactone hydrolase family K21104 - 3.1.1.101 0.00000000000000000000000966 104.0
TH1_k127_1250996_5 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000005342 88.0
TH1_k127_1251503_0 Thiamine monophosphate synthase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 338.0
TH1_k127_1251503_1 PAS fold - - - 0.0000000000000000000000000000000008249 143.0
TH1_k127_1258221_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.668e-203 638.0
TH1_k127_1258221_1 - - - - 0.00000000000000000000000006747 108.0
TH1_k127_1258221_2 OmpA-like transmembrane domain - - - 0.000003041 56.0
TH1_k127_1259408_0 PFAM AMP-dependent synthetase and ligase K00666,K01897 - 6.2.1.3 6.324e-276 861.0
TH1_k127_1259408_1 Amidohydrolase K22213 - 4.1.1.52 6.992e-212 661.0
TH1_k127_1259408_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 514.0
TH1_k127_1259408_3 PFAM fumarylacetoacetate (FAA) hydrolase K16856,K18336 - 4.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 458.0
TH1_k127_1259408_4 fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 458.0
TH1_k127_1259408_5 PFAM regulatory protein TetR K22105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 336.0
TH1_k127_1259408_6 regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000006151 229.0
TH1_k127_1259408_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000691 219.0
TH1_k127_1259408_8 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000003506 213.0
TH1_k127_1261315_0 PFAM ATP-binding region, ATPase domain protein K07637 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 597.0
TH1_k127_1261315_1 PFAM response regulator receiver K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 371.0
TH1_k127_1261315_2 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 328.0
TH1_k127_1261315_3 Clp protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 305.0
TH1_k127_1261315_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 286.0
TH1_k127_1261315_5 Dihaem cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005488 243.0
TH1_k127_1261315_6 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000000000000000001184 183.0
TH1_k127_1261315_7 Serine hydrolase K07002 - - 0.0000000000000000000000000001829 120.0
TH1_k127_1261315_8 Peptidase propeptide and YPEB domain - - - 0.000000000000000000000000001101 130.0
TH1_k127_1264304_0 Flagellar hook protein FlgE K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 486.0
TH1_k127_1264304_1 Flagellar basal-body rod protein FlgF K02391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 343.0
TH1_k127_1264304_2 flagellar basal-body rod protein K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007807 263.0
TH1_k127_1264304_3 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000000000000000000000000000000000000000000000000000001281 236.0
TH1_k127_1264304_4 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000000000000000006731 229.0
TH1_k127_1264304_5 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000000000000000000000000000000000000001797 198.0
TH1_k127_1269381_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 3.284e-205 649.0
TH1_k127_1269381_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 399.0
TH1_k127_1269381_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000003075 52.0
TH1_k127_1285076_0 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 410.0
TH1_k127_1285076_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000001256 138.0
TH1_k127_1285076_3 Cell division protein ZipA - - - 0.000000000000000000000000000000001938 131.0
TH1_k127_1290152_0 Cytochrome c assembly protein - - - 3.633e-222 695.0
TH1_k127_1290152_1 ResB-like family K07399 - - 2.451e-201 641.0
TH1_k127_1290152_2 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000004331 237.0
TH1_k127_1290152_3 - - - - 0.000000000000000000000000000000000000000000000000000009991 192.0
TH1_k127_1292202_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 557.0
TH1_k127_1292202_1 Protein of unknown function (DUF1631) - - - 0.00000001095 61.0
TH1_k127_1296024_0 homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 578.0
TH1_k127_1296024_1 Diguanylate cyclase K21023 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 505.0
TH1_k127_1296024_2 Protein of unknown function (DUF3567) - - - 0.00000000000000000000000000000000000006307 144.0
TH1_k127_1297700_0 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 423.0
TH1_k127_1297700_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 334.0
TH1_k127_1299174_0 SMC domain protein - - - 0.0 1410.0
TH1_k127_1299174_1 urea carboxylase - - - 8.452e-232 726.0
TH1_k127_1299174_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 539.0
TH1_k127_1299174_3 Pectinacetylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 342.0
TH1_k127_1299174_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 332.0
TH1_k127_1313509_0 Filamentous haemagglutinin family outer membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 579.0
TH1_k127_1324717_0 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 443.0
TH1_k127_1324717_1 Transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 432.0
TH1_k127_1324717_2 - - - - 0.00000000000000001749 83.0
TH1_k127_1324717_3 fad dependent oxidoreductase K07137 - - 0.000000000000001224 77.0
TH1_k127_1324717_4 - - - - 0.00000002097 57.0
TH1_k127_1331588_0 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 508.0
TH1_k127_1331588_1 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 420.0
TH1_k127_1331588_2 Nudix hydrolase K08310 - 3.6.1.67 0.0000000000002354 69.0
TH1_k127_1334405_0 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 333.0
TH1_k127_1355455_0 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 453.0
TH1_k127_1355455_1 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 404.0
TH1_k127_1355455_2 ATPase, P-type K01531 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 309.0
TH1_k127_1371190_0 Peptidase family M3 K01414 - 3.4.24.70 1.905e-251 779.0
TH1_k127_1371190_1 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 597.0
TH1_k127_1371190_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 386.0
TH1_k127_1371190_3 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 338.0
TH1_k127_1371190_4 Glutaredoxin - - - 0.000000000000000000000000000000000000000000000000000002848 197.0
TH1_k127_1371190_5 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000004205 187.0
TH1_k127_1403448_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 536.0
TH1_k127_1403448_1 Fic/DOC family - - - 0.0006972 44.0
TH1_k127_1413486_0 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005184 259.0
TH1_k127_1413486_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000003596 211.0
TH1_k127_1413486_2 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000008903 158.0
TH1_k127_1413486_3 Protein of unknown function (DUF3592) - - - 0.0000002996 63.0
TH1_k127_1433099_0 Belongs to the UbiD family K03182 - 4.1.1.98 5.976e-318 977.0
TH1_k127_1433099_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.613e-258 799.0
TH1_k127_1433099_2 lytic transglycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 340.0
TH1_k127_1433099_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004555 265.0
TH1_k127_1433099_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000001273 248.0
TH1_k127_1433099_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000007429 207.0
TH1_k127_1433099_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000006503 163.0
TH1_k127_1433099_7 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000001121 98.0
TH1_k127_1435453_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 1.578e-229 716.0
TH1_k127_1435453_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 340.0
TH1_k127_1435453_2 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 312.0
TH1_k127_1435453_3 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000000000000000007595 162.0
TH1_k127_1438492_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 502.0
TH1_k127_1438492_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 398.0
TH1_k127_1438492_2 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 362.0
TH1_k127_1438492_3 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000000000000000000000000000001646 166.0
TH1_k127_1438492_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000001491 144.0
TH1_k127_1454382_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 431.0
TH1_k127_1454382_1 Protein of unknown function (DUF455) - - - 0.00000000000000000001689 95.0
TH1_k127_1454382_2 Belongs to the UPF0061 (SELO) family - - - 0.0000000000000000002069 102.0
TH1_k127_1470605_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0 1204.0
TH1_k127_1470605_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 538.0
TH1_k127_1470605_2 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 468.0
TH1_k127_1470605_3 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 353.0
TH1_k127_1470605_4 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000006897 155.0
TH1_k127_1482267_0 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 520.0
TH1_k127_1482267_1 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 434.0
TH1_k127_1482267_10 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000006109 137.0
TH1_k127_1482267_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 414.0
TH1_k127_1482267_3 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 413.0
TH1_k127_1482267_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 308.0
TH1_k127_1482267_5 Cytochrome B561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002499 280.0
TH1_k127_1482267_6 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002118 276.0
TH1_k127_1482267_7 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002849 257.0
TH1_k127_1482267_8 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008413 245.0
TH1_k127_1482267_9 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003946 239.0
TH1_k127_1483659_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 547.0
TH1_k127_1483659_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000001623 117.0
TH1_k127_1483659_2 O-Antigen ligase - - - 0.0000000000000002406 93.0
TH1_k127_1512164_0 Domain of unknown function (DUF3391) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 467.0
TH1_k127_1517569_0 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 466.0
TH1_k127_1517569_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 328.0
TH1_k127_1517569_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000009612 170.0
TH1_k127_1517569_3 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000000000003155 106.0
TH1_k127_1524887_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1030.0
TH1_k127_1524887_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 1.273e-261 820.0
TH1_k127_1524887_2 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004046 262.0
TH1_k127_1524887_3 FMN binding - - - 0.00000000000000000000000000000000000000000000000002784 184.0
TH1_k127_1524887_4 - - - - 0.000000000000000075 84.0
TH1_k127_154140_0 Signal transducing histidine kinase, homodimeric domain K02487,K06596 - - 0.0 1260.0
TH1_k127_154140_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 361.0
TH1_k127_154140_2 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001882 263.0
TH1_k127_1556178_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 2.481e-215 673.0
TH1_k127_1556178_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 353.0
TH1_k127_1556178_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000006641 222.0
TH1_k127_1558617_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 474.0
TH1_k127_1558617_1 Glycine cleavage system T protein K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 310.0
TH1_k127_1558617_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000002668 243.0
TH1_k127_1564647_0 Uncharacterized protein conserved in bacteria C-term(DUF2220) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 389.0
TH1_k127_1564647_1 Protein of unknown function (DUF4255) - - - 0.0000007958 57.0
TH1_k127_1570881_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1127.0
TH1_k127_1570881_1 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 300.0
TH1_k127_1571616_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 1.464e-285 931.0
TH1_k127_1571616_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 315.0
TH1_k127_1583393_0 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 434.0
TH1_k127_1583393_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 418.0
TH1_k127_1583393_2 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 358.0
TH1_k127_1583393_3 Flavodoxin domain K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 304.0
TH1_k127_1583393_4 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009796 268.0
TH1_k127_1588842_0 Major facilitator superfamily K05939 - 2.3.1.40,6.2.1.20 1.8e-322 997.0
TH1_k127_1588842_1 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 7.444e-222 692.0
TH1_k127_1588842_2 Mota tolq exbb proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 353.0
TH1_k127_1588842_3 Uncharacterized protein conserved in bacteria (DUF2145) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 299.0
TH1_k127_1588842_4 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000000000000000000000000000001898 203.0
TH1_k127_1588842_5 Major facilitator superfamily K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000008897 140.0
TH1_k127_1588842_6 TIGRFAM TonB family protein K03832 - - 0.000000000000000000000000001261 115.0
TH1_k127_1588842_7 Belongs to the peptidase S8 family - - - 0.000000000000000000000002584 112.0
TH1_k127_1588842_8 - - - - 0.0000000000000000003264 93.0
TH1_k127_1612182_0 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 4.254e-215 672.0
TH1_k127_1612182_1 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 597.0
TH1_k127_1612182_2 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 473.0
TH1_k127_1612182_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 368.0
TH1_k127_1617692_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 432.0
TH1_k127_1617692_1 Protein of unknown function (DUF3034) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 284.0
TH1_k127_1645572_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 436.0
TH1_k127_1645572_1 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 331.0
TH1_k127_1645572_2 photoreceptor activity - - - 0.0000000000000000000000000000000000000000000003093 186.0
TH1_k127_1645572_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000001873 173.0
TH1_k127_1649852_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 1.465e-255 796.0
TH1_k127_1649852_1 diguanylate cyclase K21019 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 363.0
TH1_k127_1649852_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000002004 225.0
TH1_k127_1649852_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000005321 190.0
TH1_k127_1661348_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239 - - 7.717e-246 767.0
TH1_k127_1661348_1 - - - - 0.0000000000000000008594 89.0
TH1_k127_1669442_0 RNB K01147 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 452.0
TH1_k127_1669442_1 TonB C terminal K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 288.0
TH1_k127_1669442_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000008399 164.0
TH1_k127_1694584_0 Likely ribonuclease with RNase H fold. K06959 - - 0.0 1095.0
TH1_k127_1694584_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000002209 225.0
TH1_k127_1694584_2 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000001793 92.0
TH1_k127_1706368_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 606.0
TH1_k127_1706368_1 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 606.0
TH1_k127_1706368_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 509.0
TH1_k127_1706368_3 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 305.0
TH1_k127_1706368_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005501 265.0
TH1_k127_1706368_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008717 251.0
TH1_k127_1706368_6 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000001109 137.0
TH1_k127_1706368_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000005004 100.0
TH1_k127_1718388_0 Peptidase C39 family K13409 - - 0.0 1064.0
TH1_k127_1718388_1 HlyD family secretion protein K13408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 480.0
TH1_k127_1718388_2 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.0000000009289 61.0
TH1_k127_1725428_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 8.602e-255 788.0
TH1_k127_1725428_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000004985 216.0
TH1_k127_1731594_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 568.0
TH1_k127_1735055_0 ATP synthase A chain K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 514.0
TH1_k127_1735055_1 ATP synthase I chain - - - 0.000000000000000000000000000000000004748 138.0
TH1_k127_1738085_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0 1197.0
TH1_k127_1738085_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 417.0
TH1_k127_1738085_2 2-hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 402.0
TH1_k127_1738085_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000009304 245.0
TH1_k127_1738085_4 Type VI secretion, TssG K11895 - - 0.0000000000000000000000000000000000000000001934 160.0
TH1_k127_1738085_6 Oxidoreductase-like protein, N-terminal - - - 0.0000000000000000000000000405 112.0
TH1_k127_1744396_0 Amidohydrolase family K01465 - 3.5.2.3 1.838e-231 721.0
TH1_k127_1744396_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 585.0
TH1_k127_1744396_2 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 566.0
TH1_k127_1744396_3 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 312.0
TH1_k127_1744396_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000003939 258.0
TH1_k127_1744396_5 uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000008007 252.0
TH1_k127_1744396_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000000992 186.0
TH1_k127_1772034_0 Uncharacterised signal transduction histidine kinase domain (DUF2222) K07678 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 311.0
TH1_k127_1772034_1 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000006155 171.0
TH1_k127_1778894_0 DEAD-like helicases superfamily K07012 - - 1.027e-224 705.0
TH1_k127_1778894_1 CRISPR-associated protein (Cas_Cas5) K19119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 330.0
TH1_k127_1786746_0 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 385.0
TH1_k127_1786746_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0000000000000000000000000000000000000007227 152.0
TH1_k127_1795859_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1600.0
TH1_k127_1795859_1 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 3.926e-273 845.0
TH1_k127_1795859_2 D-Ala-D-Ala carboxypeptidase 3 (S13) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 407.0
TH1_k127_1795859_3 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 339.0
TH1_k127_1801170_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1131.0
TH1_k127_1801170_1 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000427 283.0
TH1_k127_1801170_2 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000008037 164.0
TH1_k127_1801170_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000002782 161.0
TH1_k127_1801170_4 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000863 143.0
TH1_k127_1803423_0 Gram-negative porin - - - 0.0000000000000000000000000000000000000000000000000754 191.0
TH1_k127_1812273_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 557.0
TH1_k127_1812273_1 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 378.0
TH1_k127_1812273_2 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 388.0
TH1_k127_1812273_3 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.000000000000000000000000000000000000004592 150.0
TH1_k127_1812273_4 Tetratricopeptide repeat - - - 0.00041 49.0
TH1_k127_1823296_0 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 8.067e-214 666.0
TH1_k127_1823296_1 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 298.0
TH1_k127_1823296_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000001114 220.0
TH1_k127_1823296_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000005022 217.0
TH1_k127_1823296_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000001592 211.0
TH1_k127_1823296_5 - - - - 0.0000000000000000000000000000000000000000000000000000004313 199.0
TH1_k127_1823296_6 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000001179 172.0
TH1_k127_1823296_7 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000002653 168.0
TH1_k127_1830959_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 612.0
TH1_k127_1830959_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 527.0
TH1_k127_1830959_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 488.0
TH1_k127_1830959_3 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 355.0
TH1_k127_1830959_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000004619 61.0
TH1_k127_1865408_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1868.0
TH1_k127_186805_0 Protein of unknown function (DUF3304) - - - 0.000000000000000000000000000000000000000000000000000000000000001635 221.0
TH1_k127_186805_1 Protein of unknown function (DUF3304) - - - 0.0000000000000000000000000000000000000000000000000000000000005455 214.0
TH1_k127_186805_2 Domain of unknown function (DUF4123) - - - 0.0000000005405 62.0
TH1_k127_1871483_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 8.131e-199 620.0
TH1_k127_1871483_1 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 515.0
TH1_k127_1871483_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 367.0
TH1_k127_1871483_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000000000000000001206 231.0
TH1_k127_1871483_4 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000003678 117.0
TH1_k127_1875382_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.72e-237 746.0
TH1_k127_1888820_0 Uncharacterised protein family (UPF0149) K07039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 395.0
TH1_k127_1888820_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 352.0
TH1_k127_1888820_2 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001131 256.0
TH1_k127_1888820_3 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000002824 189.0
TH1_k127_1891005_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 483.0
TH1_k127_1891005_1 CHASE3 domain - - - 0.000000000000000000000000000000000000000000000000000000001356 210.0
TH1_k127_1891005_2 Domain of unknown function (DUF1857) - - - 0.0000000000000000000000000000000000000000000000000000001261 198.0
TH1_k127_1892165_0 modulator of DNA gyrase K03568 - - 2.213e-274 849.0
TH1_k127_1892165_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.432e-257 796.0
TH1_k127_1892165_10 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000000004684 233.0
TH1_k127_1892165_11 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000000000005567 229.0
TH1_k127_1892165_12 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000000000000000006836 196.0
TH1_k127_1892165_13 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000000006421 188.0
TH1_k127_1892165_14 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000000000000000000001641 177.0
TH1_k127_1892165_15 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000000000009213 154.0
TH1_k127_1892165_16 Ribosomal protein L30 K02907 - - 0.000000000000000000000006286 102.0
TH1_k127_1892165_17 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000001058 77.0
TH1_k127_1892165_2 alpha/beta hydrolase fold K01046 - 3.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 390.0
TH1_k127_1892165_3 Proteobacterial lipase chaperone protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 352.0
TH1_k127_1892165_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 332.0
TH1_k127_1892165_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 308.0
TH1_k127_1892165_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 302.0
TH1_k127_1892165_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 285.0
TH1_k127_1892165_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009346 239.0
TH1_k127_1892165_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009129 238.0
TH1_k127_1894905_0 Cation transport protein K03498 - - 2.358e-210 661.0
TH1_k127_1894905_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 4.135e-204 638.0
TH1_k127_1894905_2 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 383.0
TH1_k127_1894905_3 TrkA-C domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 332.0
TH1_k127_191927_0 PrkA AAA domain K07180 - - 0.0 1046.0
TH1_k127_191927_1 SpoVR like protein K06415 - - 1.176e-255 796.0
TH1_k127_191927_2 Belongs to the UPF0229 family K09786 - - 4.705e-251 778.0
TH1_k127_1924062_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 616.0
TH1_k127_1924062_1 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 533.0
TH1_k127_1924062_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 386.0
TH1_k127_1924062_3 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 345.0
TH1_k127_1924062_4 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 302.0
TH1_k127_1933222_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1350.0
TH1_k127_1943708_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 314.0
TH1_k127_1943708_1 - - - - 0.0000000000000000000000001357 117.0
TH1_k127_1944318_0 haemagglutination activity domain - - - 0.00000000000000000000000000000000000000000000663 188.0
TH1_k127_1944671_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 331.0
TH1_k127_1944671_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 291.0
TH1_k127_1945744_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 562.0
TH1_k127_1945744_1 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 541.0
TH1_k127_1945744_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 400.0
TH1_k127_1945744_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 366.0
TH1_k127_1945744_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 360.0
TH1_k127_1945744_5 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000000001081 85.0
TH1_k127_1954104_0 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 495.0
TH1_k127_1954104_1 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000001858 201.0
TH1_k127_1954104_2 HD domain - - - 0.000000000000000000000000000000000001139 139.0
TH1_k127_1965576_0 Pfam Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 588.0
TH1_k127_1981466_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 362.0
TH1_k127_1981466_1 Laminin B (Domain IV) - - - 0.000002655 57.0
TH1_k127_1991442_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009531 254.0
TH1_k127_1997157_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 1.642e-263 829.0
TH1_k127_1997157_1 HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 364.0
TH1_k127_1997157_2 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 287.0
TH1_k127_1999975_0 E1-E2 ATPase K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007971 603.0
TH1_k127_1999975_1 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 488.0
TH1_k127_1999975_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 326.0
TH1_k127_2002035_0 Peptidase family M48 - - - 8.965e-201 639.0
TH1_k127_2002035_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 439.0
TH1_k127_2002035_2 molybdenum cofactor K03831 - 2.7.7.75 0.0000000000000000000000001677 106.0
TH1_k127_2014287_0 Protein kinase domain K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 330.0
TH1_k127_2014287_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008618 243.0
TH1_k127_2014287_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000005981 241.0
TH1_k127_2014287_3 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000001289 211.0
TH1_k127_2014287_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000000001229 147.0
TH1_k127_2018125_0 PFAM Cys Met metabolism K01740 - 2.5.1.49 1.432e-250 774.0
TH1_k127_2018125_1 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 356.0
TH1_k127_2018125_2 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000002409 197.0
TH1_k127_20193_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 6.427e-240 746.0
TH1_k127_20193_1 Bacterial protein of unknown function (DUF839) K07093 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 572.0
TH1_k127_20193_2 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 298.0
TH1_k127_20193_3 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000000000000000000000003008 166.0
TH1_k127_20193_4 Protein of unknown function (DUF2818) - - - 0.000000000000000000000000000000000004056 139.0
TH1_k127_2023394_0 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 518.0
TH1_k127_2023394_1 Lytic murein transglycosylase B K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 404.0
TH1_k127_2023394_2 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.00000000000000000000000003528 115.0
TH1_k127_2033965_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 418.0
TH1_k127_2033965_1 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000007185 224.0
TH1_k127_2040355_0 signal transduction histidine kinase - - - 6.059e-209 659.0
TH1_k127_2040355_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 282.0
TH1_k127_2040355_2 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000001182 221.0
TH1_k127_2040355_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000004491 173.0
TH1_k127_2040355_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. K14980 - 2.7.13.3 0.000000000000000000000001342 115.0
TH1_k127_2047210_0 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 357.0
TH1_k127_2047210_1 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000002787 198.0
TH1_k127_2050468_0 Aminotransferase class I and II K00832 - 2.6.1.57 1.114e-216 677.0
TH1_k127_2050468_1 Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 344.0
TH1_k127_2050468_2 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 299.0
TH1_k127_2050468_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 292.0
TH1_k127_2050468_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001842 259.0
TH1_k127_2050468_5 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000004213 219.0
TH1_k127_2050468_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000003656 222.0
TH1_k127_2050468_7 response regulator - - - 0.000000000000000000000000000000000000000000000000005858 181.0
TH1_k127_2050468_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000001481 153.0
TH1_k127_2051100_0 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 357.0
TH1_k127_2051100_1 histidine kinase, dimerisation and phosphoacceptor region K05962 - 2.7.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 322.0
TH1_k127_2051100_2 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000004854 169.0
TH1_k127_20678_0 rhs element vgr protein K11904 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 408.0
TH1_k127_20678_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000847 264.0
TH1_k127_2092431_0 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 513.0
TH1_k127_2092431_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 433.0
TH1_k127_2109618_0 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 1.792e-240 746.0
TH1_k127_2109618_1 Pectinacetylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 325.0
TH1_k127_2109618_2 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0002559 46.0
TH1_k127_2137252_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.356e-262 812.0
TH1_k127_2137252_1 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 361.0
TH1_k127_2137252_2 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 356.0
TH1_k127_2137252_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008969 278.0
TH1_k127_2137252_4 Bacterial protein of unknown function (DUF898) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004204 280.0
TH1_k127_2137252_5 Belongs to the glutamate synthase family - - - 0.00000000000000000000000000000000001363 138.0
TH1_k127_2142707_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.233e-280 863.0
TH1_k127_2142707_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000003849 228.0
TH1_k127_2159013_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 6.072e-286 883.0
TH1_k127_2164991_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 3.315e-212 664.0
TH1_k127_2164991_1 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009978 442.0
TH1_k127_2164991_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 383.0
TH1_k127_2164991_3 PBP superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 320.0
TH1_k127_2164991_4 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000000000000000000000003311 159.0
TH1_k127_2164991_5 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000000000000000003346 154.0
TH1_k127_2164991_6 Transcriptional regulator K10914 - - 0.0000000000000000000000000000000000000001159 161.0
TH1_k127_2171064_0 Putative exonuclease SbcCD, C subunit - - - 0.0 1060.0
TH1_k127_2171064_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 429.0
TH1_k127_2171064_2 Domain of unknown function (DUF4194) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 302.0
TH1_k127_2175321_0 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000001749 241.0
TH1_k127_2176416_0 ABC transporter K02056 - 3.6.3.17 3.451e-226 707.0
TH1_k127_2176416_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 578.0
TH1_k127_2176416_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000001075 180.0
TH1_k127_2196688_0 Pfam:DUF2424 K03379,K18371,K21730 - 1.14.13.160,1.14.13.22,1.14.13.226 1.534e-225 708.0
TH1_k127_2196688_1 Putative diguanylate phosphodiesterase - - - 0.00000002403 55.0
TH1_k127_2196937_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1189.0
TH1_k127_2196937_1 Transporter - - - 1.152e-229 716.0
TH1_k127_2196937_2 UPF0114 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 290.0
TH1_k127_2196937_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000005602 57.0
TH1_k127_2200161_0 Alkyl hydroperoxide reductase K03387 - - 7.898e-239 747.0
TH1_k127_2200161_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 373.0
TH1_k127_2200161_2 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 354.0
TH1_k127_2200161_3 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 359.0
TH1_k127_2200161_4 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.00000000000000000000000000000000000000000000003388 174.0
TH1_k127_2200839_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0 1050.0
TH1_k127_2201349_0 Aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 433.0
TH1_k127_2201349_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 402.0
TH1_k127_2201429_0 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 336.0
TH1_k127_2201429_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000001102 102.0
TH1_k127_2218343_0 PFAM CoA-binding domain protein K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 610.0
TH1_k127_2218343_1 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 362.0
TH1_k127_2218343_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 344.0
TH1_k127_2218343_3 Belongs to the glycosyltransferase 26 family K05946,K13660 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 328.0
TH1_k127_2218343_4 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000002384 206.0
TH1_k127_2218343_5 diguanylate cyclase - - - 0.000000000000000000000000000002979 136.0
TH1_k127_2227752_0 Peptidase dimerisation domain - - - 4.188e-214 676.0
TH1_k127_2227752_1 OHCU decarboxylase K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.0000000000000000000000000000000000000000000002653 168.0
TH1_k127_2227752_2 Leucine-rich repeat (LRR) protein - - - 0.00000000000000000000000000003172 125.0
TH1_k127_2228158_0 Helicase - - - 6.848e-207 654.0
TH1_k127_2234002_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 4.904e-213 664.0
TH1_k127_2234002_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 1.252e-194 612.0
TH1_k127_2234002_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001811 254.0
TH1_k127_223620_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 2.108e-250 779.0
TH1_k127_223620_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 437.0
TH1_k127_223620_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000009059 89.0
TH1_k127_2249507_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 1.047e-211 659.0
TH1_k127_2249507_1 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.0000000000000000001638 98.0
TH1_k127_2252433_0 Belongs to the bacterial solute-binding protein 3 family K02030,K09969,K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 320.0
TH1_k127_2252433_1 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 313.0
TH1_k127_2252433_2 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000006304 220.0
TH1_k127_2252433_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000003067 133.0
TH1_k127_2273041_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 1.877e-280 868.0
TH1_k127_2273041_1 Transcriptional regulator, LysR family K03576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003075 247.0
TH1_k127_22854_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 475.0
TH1_k127_22854_1 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 376.0
TH1_k127_22854_2 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 355.0
TH1_k127_22854_3 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000005648 151.0
TH1_k127_2287275_0 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 387.0
TH1_k127_2287275_1 histidine kinase HAMP region domain protein K03406,K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000007127 243.0
TH1_k127_2290667_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 9.818e-280 864.0
TH1_k127_2290667_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 372.0
TH1_k127_2304474_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 2.582e-202 632.0
TH1_k127_2304474_1 alpha/beta hydrolase fold K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 347.0
TH1_k127_2304474_2 NADPH dehydrogenase K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 329.0
TH1_k127_2304474_3 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000004971 233.0
TH1_k127_2304474_4 Protein of unknown function (DUF2938) - - - 0.00000000000000000000000000000000000000000000000000000000000009982 218.0
TH1_k127_2304474_5 alpha beta K21104 - 3.1.1.101 0.0000000000000000000000000000000000000000000000001074 190.0
TH1_k127_2304474_6 PFAM peptidylprolyl isomerase FKBP-type K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000002934 162.0
TH1_k127_2304474_7 Protein of unknown function (DUF2798) - - - 0.00000000000000000000000005832 108.0
TH1_k127_2304474_8 Histidine kinase K11527 - 2.7.13.3 0.00002726 49.0
TH1_k127_2313675_0 phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 303.0
TH1_k127_2313675_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 299.0
TH1_k127_2313675_2 MAATS-type transcriptional repressor, C-terminal region K03577 - - 0.00000000000000000000000000000000000000000000000000000000000004141 221.0
TH1_k127_2313675_3 Domain of unknown function (DUF1840) - - - 0.00000000000000000000000004683 110.0
TH1_k127_2313675_4 Transposase - - - 0.000000000000411 72.0
TH1_k127_2328734_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 8.302e-214 670.0
TH1_k127_2338938_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 339.0
TH1_k127_2338938_1 Flavodoxin-like fold K00355,K11746,K11748 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 302.0
TH1_k127_2338938_2 Uncharacterized protein conserved in bacteria (DUF2135) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001427 274.0
TH1_k127_2339253_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 501.0
TH1_k127_2339253_1 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000002641 96.0
TH1_k127_236501_0 virulence-associated E family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 430.0
TH1_k127_2367321_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 2.261e-290 897.0
TH1_k127_2367321_1 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 429.0
TH1_k127_2367321_2 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0000000000000000000000000000000000000000000000005402 175.0
TH1_k127_2373552_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1150.0
TH1_k127_2373552_1 PFAM transposase IS66 - - - 0.0000000001483 63.0
TH1_k127_2378218_0 Rhs element Vgr protein K11904 - - 1.977e-242 785.0
TH1_k127_2378218_1 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 321.0
TH1_k127_2378218_2 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 320.0
TH1_k127_2419374_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 9.337e-241 750.0
TH1_k127_2419374_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 7.477e-222 699.0
TH1_k127_2419374_2 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 515.0
TH1_k127_2419374_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 510.0
TH1_k127_2419374_4 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 391.0
TH1_k127_2419374_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 326.0
TH1_k127_2419374_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000001872 143.0
TH1_k127_2419374_7 PFAM Anti sigma-E protein RseA K03597 - - 0.00000000000000000002289 100.0
TH1_k127_2419374_8 Transglutaminase/protease-like homologues - - - 0.000043 53.0
TH1_k127_2427735_0 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 505.0
TH1_k127_2427735_1 ATPase MipZ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 415.0
TH1_k127_2427735_2 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 359.0
TH1_k127_2427735_3 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.000000000000000000000000000000000000004454 151.0
TH1_k127_2427735_4 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000008473 143.0
TH1_k127_2427735_5 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000002543 101.0
TH1_k127_2433697_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1359.0
TH1_k127_2433697_1 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000143 174.0
TH1_k127_243727_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 4.879e-286 893.0
TH1_k127_2450602_0 Domain of unknown function (DUF1845) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 316.0
TH1_k127_2450602_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 241.0
TH1_k127_2450602_2 Prophage CP4-57 regulatory protein (AlpA) - - - 0.000000000000000000000000000009668 119.0
TH1_k127_2451897_0 ribonuclease, Rne Rng family K08301 - - 4.756e-223 703.0
TH1_k127_2451897_1 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 447.0
TH1_k127_2451897_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 287.0
TH1_k127_2451897_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 288.0
TH1_k127_2451897_4 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 283.0
TH1_k127_2451897_5 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000001277 211.0
TH1_k127_2451897_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000003613 147.0
TH1_k127_2453808_0 Histidine kinase K07673 - 2.7.13.3 2.072e-298 928.0
TH1_k127_2453808_1 ABC transporter K01990,K13926 - - 7.278e-201 629.0
TH1_k127_2453808_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 581.0
TH1_k127_2453808_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 558.0
TH1_k127_2453808_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 404.0
TH1_k127_2453808_5 helix_turn_helix, cAMP Regulatory protein K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 330.0
TH1_k127_2453808_6 Bacterial regulatory proteins, luxR family K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 324.0
TH1_k127_2453808_7 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001762 213.0
TH1_k127_2454430_0 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002915 284.0
TH1_k127_2454430_1 Nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001766 259.0
TH1_k127_2454430_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000002224 116.0
TH1_k127_2457544_0 NADPH-dependent FMN reductase K11811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 467.0
TH1_k127_2457544_1 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 314.0
TH1_k127_2457544_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0001689 46.0
TH1_k127_2457544_2 Major intrinsic protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 286.0
TH1_k127_2457544_3 Pectinacetylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003622 292.0
TH1_k127_2457544_4 Poly-beta-hydroxybutyrate polymerase K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001461 268.0
TH1_k127_2457544_5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001507 254.0
TH1_k127_2457544_6 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000003217 198.0
TH1_k127_2457544_7 Transcriptional regulator K03892 - - 0.0000000000000000000000000000000000000000002654 160.0
TH1_k127_2457544_8 - - - - 0.0000000000000000000000001026 117.0
TH1_k127_2457544_9 COG1230 Co Zn Cd efflux system component K16264 - - 0.000000000000000001298 88.0
TH1_k127_2462063_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 1.565e-299 920.0
TH1_k127_2462063_1 Belongs to the CarA family K01956 - 6.3.5.5 4.649e-229 715.0
TH1_k127_2462063_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 2.259e-196 616.0
TH1_k127_2462063_3 Major Facilitator Superfamily K19577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 326.0
TH1_k127_2462063_4 - - - - 0.00000000000008337 79.0
TH1_k127_2469881_0 Peptidase M61 - - - 2.702e-216 684.0
TH1_k127_2471161_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 471.0
TH1_k127_2471161_1 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005796 222.0
TH1_k127_2471161_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000001795 164.0
TH1_k127_2471936_0 Nudix N-terminal K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001596 280.0
TH1_k127_2471936_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001371 261.0
TH1_k127_2471936_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000004434 207.0
TH1_k127_2502437_0 type II secretion system protein E K02454,K02652,K12276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 532.0
TH1_k127_2502437_1 type II secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 507.0
TH1_k127_2521050_0 amine dehydrogenase activity - - - 0.0 1054.0
TH1_k127_2521050_1 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 475.0
TH1_k127_2521050_2 Chalcone isomerase-like - - - 0.000005792 49.0
TH1_k127_2529850_0 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 430.0
TH1_k127_2529850_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 332.0
TH1_k127_2529850_2 Belongs to the glycosyl hydrolase family 6 K21104 - 3.1.1.101 0.0000000000000000000000000000000000000000000001239 177.0
TH1_k127_2539588_0 Protein tyrosine kinase K12132 - 2.7.11.1 3.546e-213 693.0
TH1_k127_2540017_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 7.895e-194 606.0
TH1_k127_2540017_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 575.0
TH1_k127_2540017_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 502.0
TH1_k127_2540017_3 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 512.0
TH1_k127_2540017_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000000000005397 184.0
TH1_k127_2540017_5 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000000006925 158.0
TH1_k127_2541815_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1298.0
TH1_k127_2541815_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 289.0
TH1_k127_2541815_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006343 250.0
TH1_k127_2541815_3 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000005919 235.0
TH1_k127_2541815_4 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000006593 210.0
TH1_k127_2543555_0 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000001375 109.0
TH1_k127_2543555_1 Protein with unknown function (DUF469) K09923 - - 0.00000000000000000000000002335 112.0
TH1_k127_2543555_2 bacterial OsmY and nodulation domain - - - 0.000000001621 64.0
TH1_k127_2567060_0 Phage tail sheath C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 412.0
TH1_k127_2567060_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000008277 220.0
TH1_k127_2567060_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000006023 197.0
TH1_k127_2567060_3 - - - - 0.00000000000000000000000000000000000000000000000001348 184.0
TH1_k127_2567060_4 - - - - 0.00000000000000000000000000000000000004387 149.0
TH1_k127_2567060_5 - - - - 0.0000000000000000000000000000008088 127.0
TH1_k127_2573823_0 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000002767 188.0
TH1_k127_2573823_1 Histidine kinase - - - 0.0000000000000000000000000000000000000001378 159.0
TH1_k127_2584296_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 8.568e-194 608.0
TH1_k127_2584296_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000002763 262.0
TH1_k127_2595386_0 ImpA, N-terminal, type VI secretion system K11902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 403.0
TH1_k127_2595386_1 OmpA family K02557,K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 319.0
TH1_k127_2595386_2 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.000000000000000000000000000000000000000000000000000001437 195.0
TH1_k127_2595386_3 TIGRFAM TonB family K03832 - - 0.000008682 53.0
TH1_k127_2597797_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007658 501.0
TH1_k127_2597797_1 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 319.0
TH1_k127_2597960_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 4.411e-225 708.0
TH1_k127_2597960_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 5.08e-218 679.0
TH1_k127_2597960_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.186e-203 645.0
TH1_k127_2597960_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000000000003962 141.0
TH1_k127_2597960_4 DNA topoisomerase II activity K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000003046 97.0
TH1_k127_2597960_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000149 79.0
TH1_k127_2597960_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000001757 87.0
TH1_k127_2615996_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1170.0
TH1_k127_2618559_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 314.0
TH1_k127_2618559_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000005115 151.0
TH1_k127_2621107_0 PFAM glycoside hydrolase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000104 242.0
TH1_k127_2621107_1 polysaccharide export protein K01991 - - 0.00000000000000000000000000000000000008469 157.0
TH1_k127_2621107_2 exopolysaccharide production protein ExoZ - - - 0.0000000000000000000000000000006391 137.0
TH1_k127_2621107_3 Glycosyltransferase Family 4 - - - 0.0000000000000000001375 96.0
TH1_k127_2621107_4 protein tyrosine kinase activity - - - 0.0000003128 61.0
TH1_k127_2623815_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 3.453e-249 802.0
TH1_k127_2623815_1 HDOD domain K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 410.0
TH1_k127_2624296_0 CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 511.0
TH1_k127_2638002_0 transcriptional regulator K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 503.0
TH1_k127_2638002_1 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 466.0
TH1_k127_2638002_2 Permease, YjgP YjgQ K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001303 259.0
TH1_k127_2638002_3 CbiX K03795 - 4.99.1.3 0.0000000000000000000000000000000000004832 151.0
TH1_k127_2653654_0 D-arabinono-1,4-lactone oxidase - - - 1.513e-239 747.0
TH1_k127_2653654_1 Alanine racemase, N-terminal domain - - - 1.954e-198 627.0
TH1_k127_2653654_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000009007 164.0
TH1_k127_2653654_3 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000001071 85.0
TH1_k127_2656474_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 469.0
TH1_k127_2656474_1 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000002817 191.0
TH1_k127_2657273_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1345.0
TH1_k127_2657273_1 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 342.0
TH1_k127_2657273_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 295.0
TH1_k127_2657273_3 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 298.0
TH1_k127_2657273_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 291.0
TH1_k127_2657273_5 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001213 265.0
TH1_k127_2657273_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000000000000000001807 192.0
TH1_k127_2657273_7 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000009437 125.0
TH1_k127_2666530_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 324.0
TH1_k127_2666530_1 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000112 241.0
TH1_k127_2666530_3 PEP-CTERM motif - - - 0.000009166 53.0
TH1_k127_2685113_0 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 381.0
TH1_k127_2685113_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 344.0
TH1_k127_2685113_2 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 330.0
TH1_k127_2685113_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000003984 129.0
TH1_k127_2693545_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 3.724e-218 686.0
TH1_k127_2693545_1 Carboxylesterase family - - - 0.000000000000000000000000000000401 124.0
TH1_k127_2693545_2 FeoA K04758 - - 0.00000000000000000004994 92.0
TH1_k127_2693545_3 - - - - 0.00000001025 61.0
TH1_k127_2704484_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.931e-293 902.0
TH1_k127_2704484_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 5.994e-266 835.0
TH1_k127_2704484_2 cytochrome C oxidase - - - 1.868e-234 734.0
TH1_k127_2704484_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 456.0
TH1_k127_2704484_4 Regulator K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 440.0
TH1_k127_2704484_5 cytochrome C oxidase K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 367.0
TH1_k127_2704484_6 - - - - 0.00000000000000000001993 94.0
TH1_k127_2704484_7 Protein conserved in bacteria K09926 - - 0.0000000000001102 75.0
TH1_k127_2704484_9 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.0000000003898 68.0
TH1_k127_2710404_0 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000002504 160.0
TH1_k127_2711812_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2996.0
TH1_k127_2711812_1 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 2.688e-293 902.0
TH1_k127_2711812_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 433.0
TH1_k127_2711812_3 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 410.0
TH1_k127_2711812_4 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000001001 230.0
TH1_k127_2711812_5 Transposase IS200 like K07491 - - 0.0008381 44.0
TH1_k127_2711863_0 Radical SAM - - - 1.362e-220 692.0
TH1_k127_2711863_1 propionate catabolism operon regulatory protein K02688 - - 0.00000000565 57.0
TH1_k127_2714977_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 437.0
TH1_k127_2714977_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 404.0
TH1_k127_2714977_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 385.0
TH1_k127_2715390_0 Alkaline phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 393.0
TH1_k127_2715390_1 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001445 270.0
TH1_k127_2730405_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 532.0
TH1_k127_2730405_1 Glutamine amido-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 406.0
TH1_k127_2730405_2 May be involved in recombination K03554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 379.0
TH1_k127_2730405_3 Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates K08722 - 3.1.3.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 324.0
TH1_k127_2730405_4 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 315.0
TH1_k127_2730405_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000001803 176.0
TH1_k127_2733358_0 PFAM MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 381.0
TH1_k127_2733358_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002823 254.0
TH1_k127_2733358_2 Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000000000000000000001272 204.0
TH1_k127_2733358_3 TonB C terminal K03646 - - 0.000000000000000000000000000000000000000000000000000000002537 211.0
TH1_k127_2733358_4 system-associated acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000000000000000000000002644 177.0
TH1_k127_2733358_5 Putative DNA-binding domain - - - 0.00002397 49.0
TH1_k127_273981_0 phospholipase d transphosphatidylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 339.0
TH1_k127_273981_1 Phage late control gene D protein (GPD) K11904 - - 0.000000000000000000000000000000000000000000000000002993 191.0
TH1_k127_2749821_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1088.0
TH1_k127_2749821_1 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 445.0
TH1_k127_2749821_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000001598 173.0
TH1_k127_2750884_0 Pfam:HipA_N K07154 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 399.0
TH1_k127_2750884_1 HipA-like C-terminal domain - - - 0.0000000000000000000000000002161 117.0
TH1_k127_2754191_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K13482 - 1.17.1.4 0.0 1234.0
TH1_k127_2754191_1 Amidohydrolase family K18456 - 3.5.4.32 2.657e-249 779.0
TH1_k127_2754191_2 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 351.0
TH1_k127_2754191_3 TIGRFAM xanthine dehydrogenase accessory protein XdhC K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001272 278.0
TH1_k127_2754191_4 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000001255 210.0
TH1_k127_2772876_0 UDP-galactopyranose mutase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 498.0
TH1_k127_2772876_1 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 495.0
TH1_k127_2772876_2 MobA-like NTP transferase domain - - - 0.000000000000000000000000000000000000000000001837 172.0
TH1_k127_2772876_3 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000002658 76.0
TH1_k127_2785164_0 Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 576.0
TH1_k127_2785164_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 428.0
TH1_k127_2785164_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 302.0
TH1_k127_2785164_3 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000006715 223.0
TH1_k127_2785164_4 dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000008036 175.0
TH1_k127_2798381_0 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 334.0
TH1_k127_2798381_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 297.0
TH1_k127_2798381_2 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000962 234.0
TH1_k127_2799547_0 Putative diguanylate phosphodiesterase - - - 2.33e-251 788.0
TH1_k127_2799547_1 Diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000002905 210.0
TH1_k127_2826734_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 327.0
TH1_k127_2826734_1 - - - - 0.0000000000000000000000000000000002264 141.0
TH1_k127_2826734_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000008282 57.0
TH1_k127_2831057_0 peptide transport - - - 7.256e-281 878.0
TH1_k127_2831057_1 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 422.0
TH1_k127_2831057_2 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 405.0
TH1_k127_2831057_3 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 343.0
TH1_k127_2831057_4 Protein of unknown function (DUF3348) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005599 248.0
TH1_k127_2831057_5 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.00000000000000000000000000000000000000000000000000000000000000003236 227.0
TH1_k127_2831057_6 Protein of unknown function (DUF2894) - - - 0.00000000000000000000000000000000002003 143.0
TH1_k127_2836082_0 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000003586 185.0
TH1_k127_2836082_1 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000007541 125.0
TH1_k127_2842037_0 ABC transporter transmembrane region K06147,K18893 - - 8.963e-320 986.0
TH1_k127_2842037_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001028 281.0
TH1_k127_2842037_2 Right handed beta helix region - - - 0.0000000000000001574 87.0
TH1_k127_2846776_0 ferric reductase - - - 1.325e-235 736.0
TH1_k127_2846776_1 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003882 245.0
TH1_k127_2846776_2 - - - - 0.0000000000000000000000000000000000000007293 152.0
TH1_k127_2846776_3 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000001049 150.0
TH1_k127_2854088_0 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 508.0
TH1_k127_2854088_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 426.0
TH1_k127_2854088_2 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 364.0
TH1_k127_2854088_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000007625 250.0
TH1_k127_2854088_4 Protein of unknown function (DUF3485) - - - 0.00000000000000000000000000000000000000000000000000000000000001938 224.0
TH1_k127_2854088_5 - - - - 0.0000000000000000000000002204 115.0
TH1_k127_285416_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1122.0
TH1_k127_2875508_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 542.0
TH1_k127_2875508_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001202 275.0
TH1_k127_2878955_0 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000001759 144.0
TH1_k127_2878955_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000002966 115.0
TH1_k127_2881632_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.149e-267 829.0
TH1_k127_2881632_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 389.0
TH1_k127_2881632_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 366.0
TH1_k127_2881632_3 PaaX-like protein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000001225 223.0
TH1_k127_2881632_4 - - - - 0.000000000000000000000000000000000000000000000000000000006166 209.0
TH1_k127_2881632_5 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000001437 105.0
TH1_k127_2895642_0 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 606.0
TH1_k127_2895642_1 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.0000000000000000000000000000000000000000000000001185 186.0
TH1_k127_2909420_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1045.0
TH1_k127_2909420_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 8.219e-210 664.0
TH1_k127_2909420_2 Ammonium Transporter K03320 - - 2.753e-202 636.0
TH1_k127_2909420_3 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 603.0
TH1_k127_2909420_4 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000001868 210.0
TH1_k127_2909420_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000000000005426 180.0
TH1_k127_2909420_6 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000006336 143.0
TH1_k127_2909420_7 Pfam:DUF1049 K08992 - - 0.0000000000000000000000000000000000007685 146.0
TH1_k127_2910641_0 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 331.0
TH1_k127_2910641_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 325.0
TH1_k127_2910641_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000003658 214.0
TH1_k127_2918274_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 381.0
TH1_k127_2918274_1 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000009347 188.0
TH1_k127_2922526_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 351.0
TH1_k127_2922526_1 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 321.0
TH1_k127_2922526_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000002677 139.0
TH1_k127_2928826_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.0 1123.0
TH1_k127_2928826_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 549.0
TH1_k127_2928826_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 313.0
TH1_k127_2928826_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000009632 175.0
TH1_k127_2944615_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 1.269e-247 804.0
TH1_k127_2944615_1 TIGRFAM type I secretion membrane fusion protein, HlyD family K12542 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 444.0
TH1_k127_2944615_2 Outer membrane efflux protein K12543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 436.0
TH1_k127_2944615_3 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000004596 72.0
TH1_k127_2945489_0 TIGRFAM adhesin HecA family 20-residue repeat (two copies), filamentous hemagglutinin family N-terminal domain K15125 - - 1.326e-234 786.0
TH1_k127_2945489_1 LysR substrate binding domain K18900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 317.0
TH1_k127_2945489_2 2-hydroxychromene-2-carboxylate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000375 283.0
TH1_k127_2945489_3 alpha/beta hydrolase fold - - - 0.00000000000002991 76.0
TH1_k127_2960972_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 8.819e-196 612.0
TH1_k127_2960972_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 606.0
TH1_k127_2960972_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 462.0
TH1_k127_2960972_3 Anti-sigma-K factor rskA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000555 263.0
TH1_k127_2960972_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001718 255.0
TH1_k127_2960972_5 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000000000000001384 234.0
TH1_k127_2960972_6 Protein of unknown function (DUF3455) - - - 0.000000000000000000000000000000000000000000000000000000000002802 214.0
TH1_k127_2960972_7 Zinc-finger domain - - - 0.000000000000000000000000000000005328 129.0
TH1_k127_2960972_8 Bacteriophage replication gene A protein (GPA) - - - 0.0000000006782 63.0
TH1_k127_2960972_9 - - - - 0.000000003542 58.0
TH1_k127_2969158_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1313.0
TH1_k127_2969158_1 Protein of unknown function (DUF1800) - - - 2.079e-197 632.0
TH1_k127_2969158_2 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001967 285.0
TH1_k127_2970353_0 Polysaccharide biosynthesis protein - - - 1.934e-227 709.0
TH1_k127_2970353_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 344.0
TH1_k127_2970470_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 505.0
TH1_k127_2970470_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 342.0
TH1_k127_2970470_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 311.0
TH1_k127_2970470_3 Transcriptional regulator crp fnr family K01420 - - 0.00000000000000000000000000000000000000000000000000000000000001443 227.0
TH1_k127_2970470_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000006691 192.0
TH1_k127_2970470_5 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000001367 123.0
TH1_k127_2970470_6 - - - - 0.0000000000000000002133 94.0
TH1_k127_2979859_0 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 421.0
TH1_k127_2979859_1 OmpA-like transmembrane domain K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009113 248.0
TH1_k127_2979859_2 AraC family - - - 0.00000000000000000000006392 99.0
TH1_k127_2979859_3 Protein of unknown function (DUF3096) - - - 0.000000000000002114 77.0
TH1_k127_2982071_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 488.0
TH1_k127_2982071_1 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 383.0
TH1_k127_2982071_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 337.0
TH1_k127_2982071_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003816 269.0
TH1_k127_2982071_4 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000000005983 213.0
TH1_k127_2982071_5 Two component signalling adaptor domain - - - 0.000000000000000000001603 97.0
TH1_k127_2985793_0 flagellar hook-associated protein K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 471.0
TH1_k127_2985793_1 TIGRFAM flagellar rod assembly protein muramidase FlgJ K02395 - - 0.000000000000000000000000000000000000000000007497 163.0
TH1_k127_3013617_0 NADH flavin oxidoreductase NADH oxidase - - - 4.578e-219 687.0
TH1_k127_3013617_1 TonB-dependent receptor plug K16090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 548.0
TH1_k127_3013617_2 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K16422 - 1.1.2.3,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 497.0
TH1_k127_3013617_3 PKHD-type hydroxylase K07336 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 313.0
TH1_k127_3016811_0 Sulfate permease K03321 - - 1.983e-253 788.0
TH1_k127_303483_0 Type VI secretion system protein DotU K11892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 375.0
TH1_k127_303483_1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003411 272.0
TH1_k127_303483_2 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000595 157.0
TH1_k127_3057817_0 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002265 287.0
TH1_k127_3057817_1 Putative DNA-binding domain - - - 0.00000000000000000000000000000321 128.0
TH1_k127_3058054_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1267.0
TH1_k127_3058054_1 Histidine kinase - - - 9.774e-260 820.0
TH1_k127_3058054_10 Domain of unknown function (DUF5117) - - - 0.0000000000000003082 83.0
TH1_k127_3058054_11 Protein of unknown function (DUF3460) - - - 0.000000000000004688 77.0
TH1_k127_3058054_2 helicase K03722 - 3.6.4.12 1.082e-225 719.0
TH1_k127_3058054_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 554.0
TH1_k127_3058054_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 468.0
TH1_k127_3058054_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 457.0
TH1_k127_3058054_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 444.0
TH1_k127_3058054_7 response regulator K22010 - - 0.00000000000000000000000000000000000000000000000000000000000005244 216.0
TH1_k127_3058054_8 - - - - 0.000000000000000000000000000000000000000000000002156 181.0
TH1_k127_3058054_9 CYTH K01768 - 4.6.1.1 0.0000000000000000000000000000000000001331 155.0
TH1_k127_3061139_0 CobQ/CobB/MinD/ParA nucleotide binding domain K08252,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 367.0
TH1_k127_3061139_1 Chain length determinant protein - - - 0.0000000000000000000000000000000004264 138.0
TH1_k127_3065281_0 Domain of unknown function (DUF932) - - - 9.204e-222 691.0
TH1_k127_3065281_1 Flagellar transcriptional activator (FlhC) - - - 0.000000000000000000000000000000000000000000000000000000000005809 213.0
TH1_k127_3065281_2 Histone family protein nucleoid-structuring protein H-NS K03746 - - 0.000000000000000000000000000002019 120.0
TH1_k127_3065281_3 - - - - 0.00000000000000000000004163 103.0
TH1_k127_306817_0 ABC transporter transmembrane region K11004 - - 0.0 1076.0
TH1_k127_306817_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02022,K11003 - - 3.809e-204 649.0
TH1_k127_3070585_0 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 1.67e-196 618.0
TH1_k127_3070585_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 318.0
TH1_k127_3070585_2 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 291.0
TH1_k127_3070585_3 Biopolymer transport protein K03559,K03560 - - 0.000000000000000000000000000000000001319 143.0
TH1_k127_3088697_0 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000914 203.0
TH1_k127_3088697_1 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000000000000008817 109.0
TH1_k127_3088697_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000362 76.0
TH1_k127_3088697_3 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000001835 74.0
TH1_k127_3088697_4 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000001085 59.0
TH1_k127_3117727_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1025.0
TH1_k127_3117727_1 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 469.0
TH1_k127_3117727_2 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 441.0
TH1_k127_3117727_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 406.0
TH1_k127_3117727_4 Alpha beta hydrolase K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 359.0
TH1_k127_3117727_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 333.0
TH1_k127_3117727_6 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000001287 173.0
TH1_k127_3117727_7 Type ii and iii secretion system protein - - - 0.0000000000000000000000009645 114.0
TH1_k127_3117727_8 Histidine kinase - - - 0.000000000000000000000003399 108.0
TH1_k127_3117727_9 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000007266 93.0
TH1_k127_3125741_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1206.0
TH1_k127_3125741_1 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002886 241.0
TH1_k127_3125741_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000001221 87.0
TH1_k127_3127960_0 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 463.0
TH1_k127_3127960_1 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000009088 135.0
TH1_k127_3127960_2 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000003571 81.0
TH1_k127_3130026_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000002236 237.0
TH1_k127_3130026_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000004133 227.0
TH1_k127_3130336_0 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 560.0
TH1_k127_3130336_1 MreB/Mbl protein K04046 - - 0.00000000000000000000000000000000000000002462 164.0
TH1_k127_3133354_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 376.0
TH1_k127_3133354_1 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 348.0
TH1_k127_3133354_2 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000003298 64.0
TH1_k127_3140538_0 Amidase K01457 - 3.5.1.54 2.841e-198 626.0
TH1_k127_3140538_1 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 365.0
TH1_k127_3144793_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 513.0
TH1_k127_3144793_1 DNA circulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002643 243.0
TH1_k127_3146876_0 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000000001718 158.0
TH1_k127_3146876_1 PFAM Membrane protein of K08972 - - 0.0000000000000000000000000000000000000008014 151.0
TH1_k127_3146876_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000369 141.0
TH1_k127_3150593_0 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 569.0
TH1_k127_3150593_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 421.0
TH1_k127_3150593_2 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 353.0
TH1_k127_3150593_3 Ribosomal-protein-alanine acetyltransferase K03789,K14742 - 2.3.1.128 0.0000000000000000000000000000001006 130.0
TH1_k127_3150593_4 Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000004705 104.0
TH1_k127_3161062_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000002953 233.0
TH1_k127_3161062_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000002914 194.0
TH1_k127_3176177_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 389.0
TH1_k127_3176177_1 Periplasmic binding protein K02016,K06858 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 355.0
TH1_k127_3176177_2 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000001399 175.0
TH1_k127_3203677_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 572.0
TH1_k127_3203677_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 360.0
TH1_k127_3203677_2 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000005887 231.0
TH1_k127_3203677_3 Copper binding periplasmic protein CusF - - - 0.000000000000000000000000000000000004808 139.0
TH1_k127_3213910_0 PFAM Filamentation induced by cAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 530.0
TH1_k127_3221510_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 413.0
TH1_k127_3221510_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 404.0
TH1_k127_3221510_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 378.0
TH1_k127_3221510_3 peptidase K06194 - - 0.000000000000000000000000000000000002367 143.0
TH1_k127_3221510_4 Histidine kinase-like ATPases - - - 0.000000000000002921 81.0
TH1_k127_3225080_0 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 342.0
TH1_k127_3225080_1 fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 335.0
TH1_k127_3225080_3 cellular macromolecule catabolic process K02977,K08770 GO:0003674,GO:0003824,GO:0004430,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009628,GO:0009651,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0019637,GO:0030258,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046486,GO:0046488,GO:0046777,GO:0046834,GO:0046854,GO:0050896,GO:0052742,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000003649 132.0
TH1_k127_3231248_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001993 273.0
TH1_k127_3231248_1 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.000000000000000000000000000000000000000000000000000001914 192.0
TH1_k127_3231248_2 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.0000000000000000000000000000000000000000000000000004198 187.0
TH1_k127_3231248_3 HupE / UreJ protein K03192 - - 0.00000000000000000000000000000000000000000000000009332 186.0
TH1_k127_3231248_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000001985 169.0
TH1_k127_3241964_0 Histidine kinase - - - 6.281e-205 651.0
TH1_k127_3241964_1 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000002576 140.0
TH1_k127_3256359_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1266.0
TH1_k127_3257445_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 2137.0
TH1_k127_3257445_1 Domain of unknown function (DUF4399) - - - 0.000000000000000000000000000000000000000000000000000000000000000001335 235.0
TH1_k127_3259308_0 TIGRFAM RHS repeat-associated core domain - - - 6.293e-320 1043.0
TH1_k127_3266_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.714e-303 938.0
TH1_k127_3266_1 GMC family oxidoreductase - - - 1.368e-269 840.0
TH1_k127_3266_10 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000009978 179.0
TH1_k127_3266_11 - - - - 0.000000000000000000000000000000000155 141.0
TH1_k127_3266_2 GMC oxidoreductase - - - 3.082e-265 831.0
TH1_k127_3266_3 Involved in the biosynthesis of porphyrin-containing compound - - - 2.841e-208 661.0
TH1_k127_3266_4 Serine threonine protein kinase - - - 1.177e-204 638.0
TH1_k127_3266_5 phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 529.0
TH1_k127_3266_6 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 464.0
TH1_k127_3266_7 Copper resistance protein D - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005072 268.0
TH1_k127_3266_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000003765 246.0
TH1_k127_3266_9 Exopolysaccharide synthesis, ExoD - - - 0.000000000000000000000000000000000000000000000000000000006149 201.0
TH1_k127_3286889_0 Adenosine/AMP deaminase K19572 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 509.0
TH1_k127_3286889_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 404.0
TH1_k127_3286889_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 358.0
TH1_k127_3286889_3 - - - - 0.000000000000000000000000000000000000000000000000000000002669 207.0
TH1_k127_3286889_4 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000002771 145.0
TH1_k127_3286889_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000003802 106.0
TH1_k127_3286889_6 glutamine amidotransferase K01951 - 6.3.5.2 0.000000000000008256 79.0
TH1_k127_3292357_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 562.0
TH1_k127_3292357_1 Domain of unknown function (DUF3391) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 370.0
TH1_k127_3295611_0 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 370.0
TH1_k127_3295611_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 353.0
TH1_k127_3295611_2 phosphatase K20074 - 3.1.3.16 0.00000000000001576 74.0
TH1_k127_3295611_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.0000000000224 63.0
TH1_k127_3301645_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 9.341e-306 944.0
TH1_k127_3324063_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788,K21133 - - 0.0 1068.0
TH1_k127_3324063_1 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003631 275.0
TH1_k127_334224_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1609.0
TH1_k127_334224_1 mannitol 2-dehydrogenase activity - - - 2.423e-215 691.0
TH1_k127_334224_2 mannitol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 563.0
TH1_k127_334224_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000003784 196.0
TH1_k127_3347726_0 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 426.0
TH1_k127_3347726_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 384.0
TH1_k127_3347726_2 SapC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 334.0
TH1_k127_3347726_3 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008755 252.0
TH1_k127_3347726_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000401 124.0
TH1_k127_3358841_0 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 560.0
TH1_k127_3358841_1 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 501.0
TH1_k127_3358841_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 492.0
TH1_k127_3358841_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000001036 184.0
TH1_k127_3374483_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 310.0
TH1_k127_3374483_1 Belongs to the bacterial ribosomal protein bL31 family K02909 - - 0.0000000000000000000000000000000000000000001259 159.0
TH1_k127_3379610_0 Peptidase S15 K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 567.0
TH1_k127_3379610_1 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 490.0
TH1_k127_3379610_2 diguanylate cyclase K21019 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000003465 278.0
TH1_k127_3379610_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003101 229.0
TH1_k127_3379610_4 - - - - 0.0000000000000000000000000000000000008314 143.0
TH1_k127_3379610_5 Protein of unknown function (DUF3297) - - - 0.00000000000000000000000000000000002165 136.0
TH1_k127_3379610_6 - - - - 0.000000005044 58.0
TH1_k127_3400287_0 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 4.281e-196 621.0
TH1_k127_3400287_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 419.0
TH1_k127_3400287_2 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 407.0
TH1_k127_3400287_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000004297 240.0
TH1_k127_3423406_0 GGDEF domain - - - 2.627e-296 946.0
TH1_k127_3423406_1 Flavin-binding monooxygenase-like - - - 5.049e-226 711.0
TH1_k127_3432730_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.662e-208 654.0
TH1_k127_3432730_1 PFAM Phosphoglycerate mutase K08296 - - 0.00000000000000000000000000000000000000000000000007187 181.0
TH1_k127_3459226_0 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 3.33e-280 865.0
TH1_k127_3471637_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005377 277.0
TH1_k127_3471637_1 Electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001729 256.0
TH1_k127_3472316_0 CBS domain containing protein K03699 - - 9.247e-216 676.0
TH1_k127_3472316_1 Dehydratase family K01690 - 4.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 529.0
TH1_k127_3472316_2 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 470.0
TH1_k127_3472316_3 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000004473 196.0
TH1_k127_3472316_4 Belongs to the 'phage' integrase family - - - 0.00000002291 60.0
TH1_k127_3492080_0 Integrase core domain - - - 1.259e-279 862.0
TH1_k127_3492080_1 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 530.0
TH1_k127_3492080_2 Transposase DDE domain - - - 0.000000000000000000000000002357 119.0
TH1_k127_3492080_3 - - - - 0.000000000000000000000000003145 117.0
TH1_k127_3492080_4 COG3666 Transposase and inactivated derivatives - - - 0.0000001135 56.0
TH1_k127_3497785_0 ABC transporter K06147 - - 3.527e-314 983.0
TH1_k127_3497785_1 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 371.0
TH1_k127_3497785_2 2OG-Fe dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 361.0
TH1_k127_3497785_3 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000000000000000000006657 230.0
TH1_k127_3497785_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000003904 157.0
TH1_k127_3506847_0 Belongs to the UPF0061 (SELO) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 372.0
TH1_k127_3506847_1 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000006257 240.0
TH1_k127_3506847_2 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000006633 116.0
TH1_k127_3508492_0 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 475.0
TH1_k127_3508492_1 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 449.0
TH1_k127_3508492_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 331.0
TH1_k127_3508492_3 DNA-binding transcription factor activity - - - 0.000000000000001809 79.0
TH1_k127_3514807_0 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 340.0
TH1_k127_3514807_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 311.0
TH1_k127_3514807_2 - - - - 0.0000000000000000000003865 106.0
TH1_k127_3514807_3 Polysaccharide biosynthesis protein - - - 0.000000000000001706 89.0
TH1_k127_3514807_4 Chain length determinant protein - - - 0.0000001653 61.0
TH1_k127_3518320_0 Luciferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 359.0
TH1_k127_3518320_1 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 309.0
TH1_k127_3536219_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1350.0
TH1_k127_3539904_0 Bacterial transcriptional repressor C-terminal K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006065 281.0
TH1_k127_3539904_1 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000000007086 234.0
TH1_k127_3539904_2 Nitroreductase family - - - 0.000000000000000000000001906 105.0
TH1_k127_3543656_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 407.0
TH1_k127_3543656_1 MAPEG family - - - 0.00000000000000000000000000000000000000004003 156.0
TH1_k127_3565809_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 479.0
TH1_k127_3565809_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000009993 235.0
TH1_k127_3571778_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 447.0
TH1_k127_3571778_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 385.0
TH1_k127_3585397_0 Type IV Pilus-assembly protein W K02672 - - 0.00000000000000000003633 98.0
TH1_k127_3585397_1 TIGRFAM type IV pilus modification protein PilV K02671 - - 0.0009664 49.0
TH1_k127_3596207_0 ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 460.0
TH1_k127_3596207_1 AraC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001175 263.0
TH1_k127_36003_0 Uncharacterized protein conserved in bacteria (DUF2345) - - - 0.00000000000000000000000000000000008774 138.0
TH1_k127_361119_0 Patatin-like phospholipase K07001 - - 1.653e-219 692.0
TH1_k127_3648946_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0 1036.0
TH1_k127_3648946_1 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 386.0
TH1_k127_3648946_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000003065 252.0
TH1_k127_3648946_3 Late competence development protein ComFB - - - 0.000000000000000000000000000000000000008629 149.0
TH1_k127_3655307_0 BRO family, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 435.0
TH1_k127_3655307_1 Type III restriction enzyme, res subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 305.0
TH1_k127_3655307_2 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000006379 201.0
TH1_k127_3655307_3 - - - - 0.000000000000000000000000000000000001285 143.0
TH1_k127_3655307_4 Protein of unknown function (DUF2805) - - - 0.00000000000000000000001989 102.0
TH1_k127_3655307_5 - - - - 0.000000000000000001384 87.0
TH1_k127_3655307_6 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.00000000000002302 76.0
TH1_k127_3660618_0 Polysaccharide biosynthesis/export protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 394.0
TH1_k127_3660618_1 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 289.0
TH1_k127_3660618_2 Rubredoxin - - - 0.000000000000000000000000008901 111.0
TH1_k127_3661794_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 338.0
TH1_k127_3661794_1 Domain of unknown function (DUF3391) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 312.0
TH1_k127_3661794_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005373 259.0
TH1_k127_3661794_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000004061 157.0
TH1_k127_366282_0 Flavin-binding monooxygenase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 603.0
TH1_k127_366282_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002629 257.0
TH1_k127_366282_2 Voltage gated chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000009615 232.0
TH1_k127_366282_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0001393 44.0
TH1_k127_3687926_0 Belongs to the binding-protein-dependent transport system permease family K11960 - - 3.844e-233 733.0
TH1_k127_3687926_1 Belongs to the binding-protein-dependent transport system permease family K11961 - - 1.704e-209 655.0
TH1_k127_3687926_2 urea ABC transporter, ATP-binding protein K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 492.0
TH1_k127_3687926_3 urea ABC transporter, ATP-binding protein K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 436.0
TH1_k127_3687926_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000006311 71.0
TH1_k127_3702910_0 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 1.737e-240 747.0
TH1_k127_3702910_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 614.0
TH1_k127_3702910_2 Protein of unknown function (DUF3717) K06938 - - 0.0000000000000000000000000000000000000000000000000000000000000003702 229.0
TH1_k127_3702910_3 Protein of unknown function (DUF2834) - - - 0.0000000000000000000000001696 107.0
TH1_k127_3704150_0 Transposase and inactivated derivatives - - - 5.073e-245 756.0
TH1_k127_3704150_1 3'-5' exonuclease activity K03547 - - 1.241e-239 744.0
TH1_k127_3704150_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 578.0
TH1_k127_3724539_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 335.0
TH1_k127_3724539_1 Class ii aldolase - - - 0.00000000000000000000000000001415 119.0
TH1_k127_3732904_0 Putative phage tail protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003009 301.0
TH1_k127_3737181_0 chemotaxis sensory transducer K03406,K03776,K05874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 601.0
TH1_k127_3737181_1 Hemolysin III K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 372.0
TH1_k127_3740966_0 Secretory lipase - - - 8.311e-226 714.0
TH1_k127_3740966_1 pfkB family carbohydrate kinase K16370 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000008544 265.0
TH1_k127_3740966_2 - - - - 0.000000000000000000000000000000001331 139.0
TH1_k127_3762717_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.555e-247 772.0
TH1_k127_3768639_0 acyl-CoA dehydrogenase K20035 - - 0.0 1038.0
TH1_k127_3768639_1 Electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 544.0
TH1_k127_3768639_2 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 449.0
TH1_k127_3771950_0 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 602.0
TH1_k127_3771950_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 487.0
TH1_k127_3786257_0 Amidohydrolase family K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 565.0
TH1_k127_3786257_1 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 554.0
TH1_k127_3786257_2 Resolvase - - - 0.00003922 47.0
TH1_k127_3790298_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 4.348e-238 737.0
TH1_k127_3790298_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 554.0
TH1_k127_3790298_2 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.000000000000000000000000000000000000000000000000000000000002645 214.0
TH1_k127_3791189_0 PFAM acyl-CoA dehydrogenase domain protein - - - 6.261e-218 681.0
TH1_k127_3791189_1 Dehydrogenase K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 374.0
TH1_k127_3791189_2 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000002466 114.0
TH1_k127_382829_0 Binding-protein-dependent transport system inner membrane component K02029,K09971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 316.0
TH1_k127_382829_1 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009924 265.0
TH1_k127_382829_2 Bacterial periplasmic substrate-binding proteins K09969 - - 0.0000000000000000000000000000000000000000000000000000004499 194.0
TH1_k127_382829_3 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000003199 129.0
TH1_k127_382829_4 - - - - 0.0000000000000000000003775 98.0
TH1_k127_3833510_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 7.741e-264 820.0
TH1_k127_3833510_1 Domain of unknown function (DUF4347) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000132 266.0
TH1_k127_3833510_2 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000000000102 194.0
TH1_k127_3868168_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 381.0
TH1_k127_3868168_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 325.0
TH1_k127_3870430_0 Flavoprotein involved in K transport - - - 1.859e-216 683.0
TH1_k127_3870430_1 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 547.0
TH1_k127_3870430_2 - - - - 0.0000000001368 67.0
TH1_k127_3876695_0 carbohydrate binding K13688 - - 4.398e-297 933.0
TH1_k127_3876695_1 carbohydrate binding K13688 - - 3.588e-266 840.0
TH1_k127_387899_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 297.0
TH1_k127_387899_1 binding-protein-dependent transport systems inner membrane component K02011 - - 0.000000000000000004048 84.0
TH1_k127_3888126_0 Outer membrane receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 572.0
TH1_k127_3896264_0 Integrase, catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 533.0
TH1_k127_3896264_1 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000002743 151.0
TH1_k127_3899893_0 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 447.0
TH1_k127_3899893_1 TonB-dependent Receptor Plug Domain K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 419.0
TH1_k127_3899893_2 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000000000000009237 222.0
TH1_k127_3899893_3 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.00000000000000000000000000000000000000000001216 166.0
TH1_k127_3909324_0 Endonuclease/Exonuclease/phosphatase family K07004 - - 2.962e-251 790.0
TH1_k127_3913063_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 479.0
TH1_k127_3913063_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 443.0
TH1_k127_3913063_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006154 280.0
TH1_k127_3913063_3 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000008473 204.0
TH1_k127_3913659_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 518.0
TH1_k127_3913659_1 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 297.0
TH1_k127_3914146_0 Type VI secretion protein K11896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 554.0
TH1_k127_3914146_1 TIGRFAM type VI secretion system lysozyme-related protein K11897 - - 0.00000000000000000000000000000000000000000000000000009452 192.0
TH1_k127_3914146_2 ImpE protein K11898 - - 0.000000000000000002489 86.0
TH1_k127_3949455_0 TIGRFAM type I secretion system ATPase K12541 - - 0.0 1038.0
TH1_k127_3949455_1 LapD/MoxY periplasmic domain - - - 1.043e-246 773.0
TH1_k127_3949455_2 TIGRFAM type I secretion membrane fusion protein, HlyD family K12542 - - 1.428e-217 687.0
TH1_k127_3949455_3 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 330.0
TH1_k127_3949455_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000001776 239.0
TH1_k127_3949455_5 Chorismate lyase K03181 - 4.1.3.40 0.000000000000000001341 94.0
TH1_k127_3961981_0 type II secretion system protein E K02454 - - 3e-323 996.0
TH1_k127_3961981_1 Histidine kinase-like ATPases - - - 1.63e-201 652.0
TH1_k127_3961981_2 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 411.0
TH1_k127_3961981_3 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 406.0
TH1_k127_3961981_4 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 312.0
TH1_k127_3983534_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 553.0
TH1_k127_3983534_1 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000001674 125.0
TH1_k127_3983534_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000005511 99.0
TH1_k127_3984030_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 2.416e-242 752.0
TH1_k127_3984030_1 Aminoglycoside phosphotransferase - - - 5.417e-197 619.0
TH1_k127_3984030_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 374.0
TH1_k127_3984030_3 LysR substrate binding domain - - - 0.00000000009045 63.0
TH1_k127_3989594_0 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 0.00000004586 64.0
TH1_k127_3993547_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 2.823e-196 619.0
TH1_k127_3993547_1 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.0000000000000000000000000000000006907 132.0
TH1_k127_3993547_2 - - - - 0.000000000000007721 82.0
TH1_k127_3996700_0 Belongs to the bacterial flagellin family K02397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 483.0
TH1_k127_3996700_1 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.00000000000000000008351 90.0
TH1_k127_3996700_2 flagellar hook-associated protein K02396 - - 0.00000000000000002656 82.0
TH1_k127_4034904_0 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 526.0
TH1_k127_4034904_1 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 485.0
TH1_k127_4034904_10 membrane - - - 0.00000000000000000000000000000000000000000000000000000000671 201.0
TH1_k127_4034904_11 PFAM helix-turn-helix- domain containing protein, AraC type K18991 - - 0.000000000000000000000000000000000000000000000006435 174.0
TH1_k127_4034904_2 EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 406.0
TH1_k127_4034904_3 TIGRFAM molybdate ABC transporter K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 397.0
TH1_k127_4034904_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 304.0
TH1_k127_4034904_6 protein conserved in bacteria K09958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 280.0
TH1_k127_4034904_7 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000392 275.0
TH1_k127_4034904_8 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007922 258.0
TH1_k127_4034904_9 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000001398 224.0
TH1_k127_4035181_0 carboxylase K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 4.597e-205 660.0
TH1_k127_4035181_1 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 319.0
TH1_k127_4035181_2 glutathione-regulated potassium exporter activity - - - 0.000000000000000000000000000007878 130.0
TH1_k127_4035434_0 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 538.0
TH1_k127_4035434_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 444.0
TH1_k127_4035434_2 chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006112 245.0
TH1_k127_4035434_3 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000007865 239.0
TH1_k127_4035434_4 Thioesterase-like superfamily - - - 0.000000000000000000000000000002596 121.0
TH1_k127_4035434_5 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000000000004085 110.0
TH1_k127_4045611_0 domain, Protein K13735,K15125,K15531 - 3.2.1.156 0.00000000000000000000000003391 127.0
TH1_k127_4045611_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000223 75.0
TH1_k127_4053388_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 3.212e-247 769.0
TH1_k127_4053388_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 587.0
TH1_k127_4053388_2 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000000001616 151.0
TH1_k127_4053388_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000001617 107.0
TH1_k127_4069399_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.03e-294 907.0
TH1_k127_4069399_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.891e-240 745.0
TH1_k127_4069399_2 Sugar (and other) transporter K08151 - - 4.072e-225 702.0
TH1_k127_4069399_3 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 421.0
TH1_k127_4069399_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000005574 176.0
TH1_k127_4069399_5 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000005361 130.0
TH1_k127_4072728_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 1.485e-203 640.0
TH1_k127_4072728_1 - - - - 0.000000000000000000000000000000000000000009911 160.0
TH1_k127_4072728_2 GMC oxidoreductase K03333 - 1.1.3.6 0.00000000000000000008862 89.0
TH1_k127_408549_0 Domain of unknown function (DUF5117) - - - 4.509e-213 680.0
TH1_k127_4116684_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000009873 216.0
TH1_k127_4116684_1 Signal peptide protein - - - 0.000000000000000000000000000388 121.0
TH1_k127_4116684_2 PrpF protein K09788 - - 0.00000000000001139 73.0
TH1_k127_4120976_0 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 335.0
TH1_k127_4120976_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 300.0
TH1_k127_4120976_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000004183 129.0
TH1_k127_4124668_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 1.49e-241 786.0
TH1_k127_4124668_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 374.0
TH1_k127_4124668_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 302.0
TH1_k127_4124998_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 2.278e-244 761.0
TH1_k127_4124998_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 500.0
TH1_k127_4124998_2 Transcription regulator MerR DNA binding K08365 - - 0.000000000000000000000000000000000000000000002002 168.0
TH1_k127_4124998_3 - - - - 0.00000000000000000000000000001169 124.0
TH1_k127_4125126_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.194e-229 711.0
TH1_k127_4125126_1 Cytochrome c oxidase subunit K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 507.0
TH1_k127_4125126_2 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 299.0
TH1_k127_4125126_3 Protein of unknown function (DUF2970) - - - 0.0000000000000000000000001565 108.0
TH1_k127_4125557_0 - - - - 1.708e-194 613.0
TH1_k127_4125557_1 GH3 auxin-responsive promoter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 308.0
TH1_k127_4125557_2 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000001431 196.0
TH1_k127_4125557_3 HlyD family secretion protein K01993 - - 0.0000000000000000000000001094 119.0
TH1_k127_4127614_0 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 1.155e-209 662.0
TH1_k127_4127614_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 390.0
TH1_k127_4127614_2 Alkylphosphonate utilization operon protein PhnA K06193 - - 0.000000000000000000000000000000000000000000004851 165.0
TH1_k127_4127614_4 Right handed beta helix region - - - 0.0000000000000000000000000009356 132.0
TH1_k127_4127614_5 Bacterial Ig-like domain (group 3) K01337,K20276,K21449 - 3.4.21.50 0.000000000000000002667 101.0
TH1_k127_4127614_6 - - - - 0.000000000001197 74.0
TH1_k127_4127614_7 Multicopper oxidase K22348 - 1.16.3.3 0.0000000008766 63.0
TH1_k127_4130497_0 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 520.0
TH1_k127_4130497_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 364.0
TH1_k127_4130497_2 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 344.0
TH1_k127_4130497_3 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001037 269.0
TH1_k127_4131262_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 456.0
TH1_k127_4131262_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 422.0
TH1_k127_4131262_2 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 413.0
TH1_k127_4131262_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 402.0
TH1_k127_4131262_4 Globin - - - 0.00000000000000000000000000000000000000000002852 185.0
TH1_k127_4131262_5 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000007456 90.0
TH1_k127_4131262_6 Domain of unknown function (DUF3391) - - - 0.00000005854 55.0
TH1_k127_4133614_0 basic membrane K02058 - - 4.152e-212 664.0
TH1_k127_4133614_1 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 404.0
TH1_k127_4133614_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 342.0
TH1_k127_4133614_3 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000374 128.0
TH1_k127_4140780_0 5'-nucleotidase K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 428.0
TH1_k127_4140780_1 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 298.0
TH1_k127_4140780_2 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 291.0
TH1_k127_4158785_0 TIGRFAM type IV VI secretion system protein, DotU family K11892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 443.0
TH1_k127_4158785_1 type VI secretion protein K11891 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 379.0
TH1_k127_4159598_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006049 278.0
TH1_k127_4159598_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000001226 265.0
TH1_k127_4159598_2 Prokaryotic N-terminal methylation motif K10924 - - 0.00000000001501 71.0
TH1_k127_4169994_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 532.0
TH1_k127_4169994_1 transcriptional regulator, LuxR family - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000007888 123.0
TH1_k127_4169994_2 Major facilitator superfamily - - - 0.0000000000000009501 83.0
TH1_k127_4173693_0 Subtilase family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000001799 229.0
TH1_k127_4173693_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000003259 200.0
TH1_k127_4173693_2 Acyltransferase - - - 0.0000000000000000000000000000002053 128.0
TH1_k127_4173693_3 Protein of unknown function (DUF1653) - - - 0.000000000000000000000006447 105.0
TH1_k127_4195508_0 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 559.0
TH1_k127_4195508_1 binding-protein-dependent transport systems inner membrane component K13895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 545.0
TH1_k127_4195508_2 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 544.0
TH1_k127_4195508_3 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 475.0
TH1_k127_4210990_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1665.0
TH1_k127_4210990_1 Alpha/beta hydrolase family K06889 - - 0.00000000000000009918 85.0
TH1_k127_4219870_0 ABC transporter transmembrane region K12541 - - 2.295e-293 917.0
TH1_k127_4219870_1 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 646.0
TH1_k127_4219870_2 type I secretion membrane fusion protein, HlyD K12542 - - 0.000000000000000000000000000000000000000000000000004229 189.0
TH1_k127_4224605_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 385.0
TH1_k127_4242440_0 rRNA methyltransferase K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 366.0
TH1_k127_4242440_1 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 315.0
TH1_k127_4242440_2 AsmA family K07289 - - 0.00000000000000000000000000000000000000000000000000000363 203.0
TH1_k127_4244010_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K19707 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 347.0
TH1_k127_4244010_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000001074 248.0
TH1_k127_4244010_2 Ribonucleotide reductase subunit alpha - - - 0.0000000000000000000000000000000000000000000000000004394 187.0
TH1_k127_4244010_3 Anaerobic ribonucleoside-triphosphate reductase - - - 0.0000000000000000000000004071 105.0
TH1_k127_4244010_4 diguanylate cyclase - - - 0.000000004011 59.0
TH1_k127_4244010_5 NnrS protein K07234 - - 0.000001454 55.0
TH1_k127_4254687_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - 0.000000000000000000000000000000000000000000000000006918 187.0
TH1_k127_4254687_1 - - - - 0.0000001728 54.0
TH1_k127_4281233_0 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000477 287.0
TH1_k127_4281233_1 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11900 - - 0.00000000000000000000000004149 124.0
TH1_k127_4291564_0 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 2.586e-262 814.0
TH1_k127_4291564_1 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 571.0
TH1_k127_4291564_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000002545 150.0
TH1_k127_4291564_3 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase K03606 - - 0.00000000000000003556 80.0
TH1_k127_4300286_0 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 7.764e-264 814.0
TH1_k127_4300286_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 3.949e-236 737.0
TH1_k127_4300286_2 OmpA-like transmembrane domain K03286 - - 0.00000000000000000000000000000000000004583 148.0
TH1_k127_4300286_3 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000001863 137.0
TH1_k127_4303510_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 492.0
TH1_k127_4308718_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0 1049.0
TH1_k127_4308718_1 reductase K00059 - 1.1.1.100 8.77e-258 801.0
TH1_k127_4308718_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 9.085e-257 797.0
TH1_k127_4308718_3 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 437.0
TH1_k127_4308718_4 PFAM regulatory protein TetR - - - 0.00000000000000000001176 94.0
TH1_k127_4311873_0 SecA preprotein cross-linking domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 312.0
TH1_k127_4311873_1 membrane-associated Zn-dependent proteases 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007734 279.0
TH1_k127_4313198_0 Gkycosyl transferase family 4 group - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 563.0
TH1_k127_4313198_1 HipA-like C-terminal domain K07154 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 368.0
TH1_k127_4313198_2 TRANSCRIPTIONal - - - 0.0000000000000001468 85.0
TH1_k127_4323316_0 Protein of unknown function (DUF1173) - - - 7.453e-202 630.0
TH1_k127_4323316_1 Integrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 490.0
TH1_k127_4323316_2 - - - - 0.00000000000000000000000000000000000000000002597 165.0
TH1_k127_4323559_0 Protein of unknown function - - - 4.278e-260 831.0
TH1_k127_4325935_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 579.0
TH1_k127_4325935_1 POTRA domain K07326 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 409.0
TH1_k127_4325935_2 - - - - 0.000000000000000000001083 96.0
TH1_k127_4325935_3 haemagglutination activity domain - - - 0.0002033 49.0
TH1_k127_4329658_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000001053 185.0
TH1_k127_4329658_1 Ankyrin repeats (many copies) - - - 0.00000000008782 72.0
TH1_k127_4352989_0 GDYXXLXY protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 402.0
TH1_k127_4352989_1 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004443 285.0
TH1_k127_4375433_0 PFAM Orn Lys Arg decarboxylase K01584 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 593.0
TH1_k127_4375433_1 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000001635 172.0
TH1_k127_4375433_2 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000000008806 138.0
TH1_k127_4376003_0 Peptidase dimerisation domain K01270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 602.0
TH1_k127_4376003_1 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 432.0
TH1_k127_4376003_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000000000001824 170.0
TH1_k127_4376003_5 Protein of unknown function (DUF962) - - - 0.0000000000003103 79.0
TH1_k127_4376503_0 import inner membrane translocase subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 342.0
TH1_k127_4376503_1 Belongs to the DEAD box helicase family K05591 GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001115 260.0
TH1_k127_4379029_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 2.082e-218 680.0
TH1_k127_4379029_1 methyl-accepting chemotaxis protein K03406,K03776,K05874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 477.0
TH1_k127_4379029_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 426.0
TH1_k127_4379029_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003922 273.0
TH1_k127_4379029_4 Nudix hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000007272 229.0
TH1_k127_4379029_5 TM2 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005192 231.0
TH1_k127_4379029_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000000003681 220.0
TH1_k127_4379029_7 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000000000000001059 213.0
TH1_k127_4379029_8 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000006036 134.0
TH1_k127_4389794_0 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004163 251.0
TH1_k127_4389794_1 bond formation protein DsbB K03611 - - 0.0000000000000000000000000000000000000000000000000000009962 198.0
TH1_k127_4389794_2 Cold shock protein K03704 - - 0.0000000000000000000000000000000003237 132.0
TH1_k127_4389794_3 Trypsin-like peptidase domain - - - 0.00000000000000003662 87.0
TH1_k127_4389794_4 - - - - 0.00000004274 61.0
TH1_k127_4389794_5 chorismate binding enzyme K01665,K03342 - 2.6.1.85,4.1.3.38 0.0000007509 53.0
TH1_k127_4398325_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 395.0
TH1_k127_4398325_1 Trypsin K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000002779 220.0
TH1_k127_4398325_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000001045 68.0
TH1_k127_4409214_0 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 294.0
TH1_k127_4409214_1 Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000007235 220.0
TH1_k127_4409214_2 - - - - 0.00000000000000000123 94.0
TH1_k127_4439836_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 369.0
TH1_k127_4439836_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000001224 188.0
TH1_k127_4444272_0 urea carboxylase - - - 0.0 1133.0
TH1_k127_4444272_1 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 309.0
TH1_k127_4444272_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000003264 154.0
TH1_k127_4448836_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 8.219e-293 905.0
TH1_k127_4448836_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 5.695e-242 752.0
TH1_k127_4455361_0 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000005741 190.0
TH1_k127_4466543_0 flagellar motor switch protein K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 441.0
TH1_k127_4466543_1 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 398.0
TH1_k127_4479392_0 SMART Elongator protein 3 MiaB NifB - - - 0.0 1119.0
TH1_k127_4479392_1 Belongs to the DEAD box helicase family K05591 GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 425.0
TH1_k127_448092_0 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 286.0
TH1_k127_448092_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000252 274.0
TH1_k127_448092_2 Aminotransferase K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006044 265.0
TH1_k127_448092_3 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000001051 118.0
TH1_k127_4484212_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 535.0
TH1_k127_4484212_1 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 488.0
TH1_k127_4484212_2 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
TH1_k127_4484212_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 300.0
TH1_k127_4484212_4 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007859 284.0
TH1_k127_4485075_0 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 410.0
TH1_k127_4485075_1 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 347.0
TH1_k127_4485075_2 - - - - 0.0000000000000000000000000000000000004295 149.0
TH1_k127_4485824_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.209e-226 703.0
TH1_k127_4485824_1 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000005278 228.0
TH1_k127_4485824_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000000002729 213.0
TH1_k127_4485824_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000000000002898 176.0
TH1_k127_4485824_4 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000000000000000002475 120.0
TH1_k127_4485824_5 - - - - 0.000000000000009866 75.0
TH1_k127_4487889_0 BFD-like [2Fe-2S] binding domain K00362 - 1.7.1.15 0.0 1495.0
TH1_k127_4487889_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 1.212e-216 680.0
TH1_k127_4487889_10 - - - - 0.000000000000000000000001217 109.0
TH1_k127_4487889_11 GMC family oxidoreductase - - - 0.000000000000000000006638 92.0
TH1_k127_4487889_2 ANTAR domain protein - - - 1.93e-198 625.0
TH1_k127_4487889_3 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 488.0
TH1_k127_4487889_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 428.0
TH1_k127_4487889_5 COG1309 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 368.0
TH1_k127_4487889_7 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000002113 203.0
TH1_k127_4487889_8 Nitrite reductase K00363 - 1.7.1.15 0.000000000000000000000000000000000000000000000004119 175.0
TH1_k127_4487889_9 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000001877 154.0
TH1_k127_4495856_0 Alpha beta hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 338.0
TH1_k127_4495856_1 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005788 280.0
TH1_k127_4510818_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 407.0
TH1_k127_4510818_1 Bacterial regulatory proteins, tetR family - - - 0.000001117 52.0
TH1_k127_4518688_0 Belongs to the thiolase family K00626 - 2.3.1.9 2.894e-203 636.0
TH1_k127_4518688_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 473.0
TH1_k127_4518688_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0003504 43.0
TH1_k127_453074_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 7.729e-250 779.0
TH1_k127_453074_1 Belongs to the methyltransferase superfamily K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 530.0
TH1_k127_453074_2 Protein of unknown function, DUF599 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 368.0
TH1_k127_453074_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008444 357.0
TH1_k127_453074_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001144 273.0
TH1_k127_453074_5 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000006089 175.0
TH1_k127_453074_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000002663 121.0
TH1_k127_4537414_0 Rieske 2Fe-2S K00499 - 1.14.15.7 1.098e-219 688.0
TH1_k127_4537414_1 Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 400.0
TH1_k127_4537414_2 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004781 282.0
TH1_k127_4537414_3 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000006093 134.0
TH1_k127_4539764_0 Belongs to the GMC oxidoreductase family - - - 8.08e-201 639.0
TH1_k127_4539764_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000001061 233.0
TH1_k127_4539764_2 tetR family - - - 0.0000000000000000000000007204 111.0
TH1_k127_4539764_3 Aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000009274 95.0
TH1_k127_454109_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 497.0
TH1_k127_454109_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 351.0
TH1_k127_4559069_0 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 1.161e-250 777.0
TH1_k127_457635_0 Glycosyltransferase Family 4 - - - 0.000000000000769 79.0
TH1_k127_457635_1 PFAM O-antigen polymerase - - - 0.000000007552 67.0
TH1_k127_4582355_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 7.66e-207 662.0
TH1_k127_4582355_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 542.0
TH1_k127_4582355_2 Alpha beta hydrolase K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000001487 248.0
TH1_k127_4601234_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0 1427.0
TH1_k127_4601234_1 Pfam:T6SS_VasB K11895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 365.0
TH1_k127_4601254_0 PFAM AzlC family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002922 246.0
TH1_k127_4601254_1 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000000000000000000000000001517 203.0
TH1_k127_4601254_2 - - - - 0.000000000000000000000000000000006041 131.0
TH1_k127_4620714_0 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 444.0
TH1_k127_4620714_1 CHASE2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 446.0
TH1_k127_4620714_2 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 378.0
TH1_k127_4657553_0 Bacterial protein of unknown function (DUF853) K06915 - - 7.288e-281 869.0
TH1_k127_4657553_1 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 512.0
TH1_k127_4657553_2 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000006636 208.0
TH1_k127_4698519_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1002.0
TH1_k127_4698519_1 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 313.0
TH1_k127_4704720_0 Biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 324.0
TH1_k127_4704720_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000003124 260.0
TH1_k127_4704720_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000000000005107 225.0
TH1_k127_4704720_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000006401 218.0
TH1_k127_4704720_4 - - - - 0.0006898 49.0
TH1_k127_4708560_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1328.0
TH1_k127_4708560_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 423.0
TH1_k127_4708560_2 Glycosyl transferase family 41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008564 283.0
TH1_k127_4708560_3 Secretory lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005342 267.0
TH1_k127_4708560_4 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000001414 213.0
TH1_k127_4708560_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000000007689 154.0
TH1_k127_4710400_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1096.0
TH1_k127_4732050_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1200.0
TH1_k127_4732050_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 468.0
TH1_k127_4732050_2 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 393.0
TH1_k127_4732050_3 Thiamine monophosphate synthase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000002174 235.0
TH1_k127_4732050_4 ThiS family K03154 - - 0.00000837 55.0
TH1_k127_4740967_0 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 383.0
TH1_k127_4740967_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009906 264.0
TH1_k127_4740967_2 methyltransferase K03183,K15256 - 2.1.1.163,2.1.1.201 0.0000000000000000000003004 105.0
TH1_k127_4743102_0 Type IV secretion-system coupling protein DNA-binding domain K12071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 555.0
TH1_k127_4743102_1 Domain of unknown function (DUF4400) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 358.0
TH1_k127_4743102_2 PAAR motif - - - 0.00000000000000000000000000000000000000009642 157.0
TH1_k127_4743102_3 Type VI secretion system (T6SS), amidase effector protein 4 - - - 0.000000000000000000000000000000000000003278 146.0
TH1_k127_4745373_0 Guanine deaminase K01487 - 3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 512.0
TH1_k127_4762154_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 451.0
TH1_k127_4762154_1 Domain of unknown function (DUF4347) - - - 0.000000000000000009098 91.0
TH1_k127_4766320_0 Filamentous haemagglutinin family outer membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000003318 237.0
TH1_k127_4775852_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1379.0
TH1_k127_4775852_1 Four helix bundle sensory module for signal transduction K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 594.0
TH1_k127_4775852_2 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 357.0
TH1_k127_4775852_3 Barstar (barnase inhibitor) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 324.0
TH1_k127_4775852_4 SapC - - - 0.00000000000000000000000000000000000000000000000001965 190.0
TH1_k127_4775852_5 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000003958 172.0
TH1_k127_4775852_6 guanine-specific ribonuclease N1 and T1 K01167 - 3.1.27.3 0.00000000000000000000000000000000000004982 148.0
TH1_k127_4775852_7 Chalcone isomerase-like - - - 0.00000000000000000000000000002751 118.0
TH1_k127_4785045_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239 - - 4.894e-254 791.0
TH1_k127_4785045_1 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002623 232.0
TH1_k127_4789249_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 583.0
TH1_k127_4789249_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002966 278.0
TH1_k127_4789249_2 TIGRFAM flagellar rod assembly protein muramidase FlgJ K02395 - - 0.0000000000000000000000000000000000000000000000000000000000005421 220.0
TH1_k127_4791831_0 membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 502.0
TH1_k127_4791831_1 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 290.0
TH1_k127_4791831_2 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000006469 210.0
TH1_k127_4791831_3 Evidence 4 Homologs of previously reported genes of K09981 - - 0.00000000000000000000000000003367 119.0
TH1_k127_4791831_4 Type II secretion system protein B K02451 - - 0.0000000000000000009461 89.0
TH1_k127_4791831_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.000000000000000834 81.0
TH1_k127_4804555_0 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 537.0
TH1_k127_4804555_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 308.0
TH1_k127_4816295_0 GTPase subunit of restriction endonuclease K07452 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 574.0
TH1_k127_4816295_1 McrBC 5-methylcytosine restriction system component K19147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 544.0
TH1_k127_4816295_2 InterPro IPR007367 - - - 0.0000000000000000000000000000000000000000000000005049 183.0
TH1_k127_4816295_3 PFAM restriction modification system DNA specificity domain K01154 - 3.1.21.3 0.000000000001762 70.0
TH1_k127_482367_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 5.285e-205 642.0
TH1_k127_482367_1 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 563.0
TH1_k127_482367_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000002579 129.0
TH1_k127_4830388_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 588.0
TH1_k127_4830388_1 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 306.0
TH1_k127_4830388_2 Sporulation related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002705 269.0
TH1_k127_4840341_0 KR domain K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 299.0
TH1_k127_4840341_1 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 296.0
TH1_k127_4840341_2 Belongs to the UPF0225 family K09858 - - 0.000000000000000000000000000000000000000000000000003024 196.0
TH1_k127_4840341_4 Fe-S-cluster oxidoreductase K06940 - - 0.00000000000000000000000000000000000002442 145.0
TH1_k127_4841148_0 Uncharacterized protein conserved in bacteria (DUF2138) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000344 240.0
TH1_k127_4841148_1 COG0642 Signal transduction histidine kinase K11527 - 2.7.13.3 0.000000000000000000000000000000000003207 141.0
TH1_k127_4848608_0 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 451.0
TH1_k127_4848608_2 Domain of unknown function (DUF4280) - - - 0.00000000000000000000000000000000000000000000007442 171.0
TH1_k127_4848608_3 peptidase - - - 0.0000000000000000000000000000000000008 162.0
TH1_k127_4848608_4 - - - - 0.0000000000000000000000000001056 119.0
TH1_k127_4848608_6 PFAM Annexin repeat - - - 0.00004719 55.0
TH1_k127_4876987_0 Urea ABC transporter, urea binding protein K11959 - - 2.206e-197 617.0
TH1_k127_4876987_1 Protein of unknown function (DUF1275) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 317.0
TH1_k127_4884101_0 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 362.0
TH1_k127_4884101_1 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 334.0
TH1_k127_4884101_3 peptidase M48, Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005759 293.0
TH1_k127_4884101_4 Phosphotransferase system, mannose fructose-specific component IIA K02821 - 2.7.1.194 0.00000000000000000000000000000000000000000000000000000000000001294 218.0
TH1_k127_4884101_5 TIGRFAM phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000004831 124.0
TH1_k127_4884101_6 - - - - 0.0000000002038 70.0
TH1_k127_4884824_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 301.0
TH1_k127_4884824_1 TIGRFAM phasin family protein - - - 0.00000000000000000000000000000000001359 140.0
TH1_k127_4884824_2 PFAM aminotransferase class V - - - 0.00000000000000000000000000000001022 128.0
TH1_k127_4887169_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.779e-251 779.0
TH1_k127_4887169_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 463.0
TH1_k127_4887169_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 441.0
TH1_k127_4887169_3 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000000000000001824 150.0
TH1_k127_4887169_4 Bacterial transcriptional repressor - - - 0.0000000000000000000000007071 119.0
TH1_k127_4887169_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000001359 84.0
TH1_k127_4891452_0 Belongs to the glutamate synthase family - - - 4.448e-244 758.0
TH1_k127_4891452_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 3.555e-200 629.0
TH1_k127_4891452_2 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 312.0
TH1_k127_4891452_3 Gram-negative porin - - - 0.0000000000000000005763 89.0
TH1_k127_4897435_0 Chloramphenicol acetyltransferase K19271 - 2.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 318.0
TH1_k127_4930251_0 DEAD_2 K10844 - 3.6.4.12 7.241e-288 901.0
TH1_k127_4937772_0 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 464.0
TH1_k127_4937772_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 428.0
TH1_k127_4937772_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 388.0
TH1_k127_4937772_3 Strictosidine synthase K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 373.0
TH1_k127_4937772_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 312.0
TH1_k127_4937772_5 LemA family K03744 - - 0.0000000000000000000000006456 111.0
TH1_k127_4937772_6 Predicted membrane protein (DUF2061) - - - 0.000000000000000008713 85.0
TH1_k127_4938158_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 562.0
TH1_k127_4938158_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 393.0
TH1_k127_4938158_2 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0001525 47.0
TH1_k127_4951380_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 300.0
TH1_k127_4951380_1 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002232 263.0
TH1_k127_4965671_0 Leucine-rich repeats, outliers - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 479.0
TH1_k127_4965671_1 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000009057 180.0
TH1_k127_4968221_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 8.727e-231 723.0
TH1_k127_4968221_1 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000002526 187.0
TH1_k127_4973842_0 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000002776 256.0
TH1_k127_4973842_1 Cysteine-rich motif following a subset of SET domains K07117 - - 0.000000000000000000000000000000000000000000008462 163.0
TH1_k127_4973842_2 Belongs to the peptidase S8 family K14645 - - 0.00000000000000000000000000000000000000001775 165.0
TH1_k127_4973842_3 Sporulation domain protein - - - 0.00000000000000000000000000000000007241 143.0
TH1_k127_4976072_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 313.0
TH1_k127_4976072_1 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 292.0
TH1_k127_4976072_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001773 240.0
TH1_k127_4976072_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000001468 173.0
TH1_k127_4976072_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000005705 68.0
TH1_k127_4977037_0 alcohol dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 541.0
TH1_k127_4977037_1 Histidine kinase K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000002127 254.0
TH1_k127_4977037_2 Acetyl-coenzyme A transporter 1 - - - 0.0000000000000000000000000000000000000000000000000001369 192.0
TH1_k127_4977037_3 AMP-binding enzyme - - - 0.0000000000008283 71.0
TH1_k127_4984499_0 Cytosine deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 470.0
TH1_k127_4984499_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 368.0
TH1_k127_4984499_2 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 336.0
TH1_k127_4984499_3 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 329.0
TH1_k127_4984499_4 Eukaryotic integral membrane protein (DUF1751) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 284.0
TH1_k127_4984499_5 Protein export membrane protein K21133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003292 254.0
TH1_k127_5014223_0 ABC-type multidrug transport system, ATPase and permease K06147 - - 5.4e-323 999.0
TH1_k127_5014223_1 Belongs to the peptidase S8 family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 386.0
TH1_k127_5014223_2 Domain of unknown function (DUF1854) - - - 0.0000000000000000000000000000000000000000000000000000000002302 208.0
TH1_k127_5014223_3 ABC transporter, transmembrane region K06147 - - 0.00000000000000000000000000000000000008839 142.0
TH1_k127_5014223_4 Ferredoxin - - - 0.00000000000000000000000000001032 124.0
TH1_k127_5017523_0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 332.0
TH1_k127_5017523_1 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001061 228.0
TH1_k127_5017523_2 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000001283 185.0
TH1_k127_5017523_3 - - - - 0.0004119 51.0
TH1_k127_5023376_0 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 344.0
TH1_k127_5023376_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000004069 243.0
TH1_k127_5023376_2 Protein of unknown function (DUF3299) K09950 - - 0.0000000000000000000000000000000000000000000001748 177.0
TH1_k127_5023376_3 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000000009844 142.0
TH1_k127_5023376_4 Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000004514 99.0
TH1_k127_5029017_0 - - - - 1.584e-272 844.0
TH1_k127_5038265_0 aminotransferase class I and II K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 462.0
TH1_k127_5038265_1 2-nitropropane dioxygenase - - - 0.0000000000000004394 89.0
TH1_k127_5038265_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000001015 62.0
TH1_k127_504854_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K18916 - 1.20.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 606.0
TH1_k127_504854_1 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 565.0
TH1_k127_504854_2 phosphonate ABC transporter, inner membrane subunit K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 492.0
TH1_k127_504854_3 ATP binding cassette (Abc) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 333.0
TH1_k127_504854_4 Transposase and inactivated derivatives - - - 0.000000000000000007674 83.0
TH1_k127_504854_5 - - - - 0.00000698 50.0
TH1_k127_5050352_0 chemotaxis sensory transducer K03406,K03776,K05874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 585.0
TH1_k127_5050352_1 Four helix bundle sensory module for signal transduction K03406,K05874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 422.0
TH1_k127_5050352_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 326.0
TH1_k127_5050352_3 H-NS histone family K03746 - - 0.0000000000000000000000003319 109.0
TH1_k127_5052381_0 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 316.0
TH1_k127_5052381_1 Periplasmic solute binding protein K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007233 270.0
TH1_k127_5052381_2 CAAX protease self-immunity K07052 - - 0.000000000005627 69.0
TH1_k127_5060005_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 578.0
TH1_k127_5060005_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 540.0
TH1_k127_5060005_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 531.0
TH1_k127_5060005_3 Phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 478.0
TH1_k127_5060005_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 343.0
TH1_k127_5060005_5 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000002691 158.0
TH1_k127_5064593_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1273.0
TH1_k127_5064593_1 Phosphoesterase DHHA1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 566.0
TH1_k127_5064593_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 391.0
TH1_k127_5064593_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 373.0
TH1_k127_5064593_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003184 258.0
TH1_k127_5064593_5 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000002574 154.0
TH1_k127_5065320_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 524.0
TH1_k127_5065320_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 456.0
TH1_k127_5065320_2 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 326.0
TH1_k127_5065320_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002149 293.0
TH1_k127_5065320_4 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000002837 125.0
TH1_k127_5076141_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 454.0
TH1_k127_5076141_1 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000001764 221.0
TH1_k127_5076141_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000001628 188.0
TH1_k127_5090677_0 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 301.0
TH1_k127_5090677_1 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000002269 190.0
TH1_k127_5090677_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000003408 152.0
TH1_k127_5090677_3 GMC oxidoreductase - - - 0.0000000000000000000000000000000000005364 154.0
TH1_k127_5098204_0 Domain of unknown function (DUF2341) K03561 - - 2.023e-237 747.0
TH1_k127_5098204_1 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000000000000000223 228.0
TH1_k127_5098204_2 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000000000005071 212.0
TH1_k127_5098204_3 TonB C terminal - - - 0.00000000000000000000000000000000000000001064 163.0
TH1_k127_5098204_4 Filamentous haemagglutinin family outer membrane protein - - - 0.00000000000000000000000000000005172 135.0
TH1_k127_5098204_5 Putative porin - - - 0.000000000000000000000000000001171 125.0
TH1_k127_5101032_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.427e-284 887.0
TH1_k127_5101032_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 9.818e-279 863.0
TH1_k127_5101032_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000005097 162.0
TH1_k127_5101032_11 response to copper ion - - - 0.0000000000000000000000000000000000001761 155.0
TH1_k127_5101032_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 8.628e-214 665.0
TH1_k127_5101032_3 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 4.386e-195 616.0
TH1_k127_5101032_4 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 496.0
TH1_k127_5101032_5 Acetyl xylan esterase (AXE1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 450.0
TH1_k127_5101032_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 398.0
TH1_k127_5101032_7 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 353.0
TH1_k127_5101032_8 Rod shape-determining protein mreD K03571 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001602 272.0
TH1_k127_5101032_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002535 233.0
TH1_k127_5106003_0 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 454.0
TH1_k127_5106003_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 315.0
TH1_k127_5106003_2 Protein of unknown function (DUF4254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001381 278.0
TH1_k127_5106003_3 glycosyl transferase, family 25 K07270 - - 0.00000000000000000000000000000000000000000002514 174.0
TH1_k127_5112242_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1618.0
TH1_k127_5112242_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0 1045.0
TH1_k127_5112242_2 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 488.0
TH1_k127_5112242_3 C-terminal region of band_7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 316.0
TH1_k127_5112242_4 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000106 265.0
TH1_k127_5128227_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1148.0
TH1_k127_5128227_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 432.0
TH1_k127_5128227_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000000000000000003476 198.0
TH1_k127_5142364_0 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 1.111e-317 984.0
TH1_k127_5142364_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 399.0
TH1_k127_5148009_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 403.0
TH1_k127_5148009_1 abc transporter K02003 - - 0.000000000000000000001608 96.0
TH1_k127_5148009_2 PEP-CTERM motif - - - 0.0000000000000001363 93.0
TH1_k127_5148009_3 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0001812 44.0
TH1_k127_5150085_0 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 460.0
TH1_k127_5150085_1 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000008552 226.0
TH1_k127_5150085_2 Protein of unknown function (DUF2804) - - - 0.00000000000000000000000000000000000000000003759 164.0
TH1_k127_517578_0 serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 484.0
TH1_k127_517578_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000005041 63.0
TH1_k127_517578_2 KR domain - - - 0.000000001334 58.0
TH1_k127_5192310_0 Biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 593.0
TH1_k127_5192310_1 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 531.0
TH1_k127_5192310_2 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 439.0
TH1_k127_5192310_3 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 360.0
TH1_k127_5197044_0 signal transduction protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001486 245.0
TH1_k127_522083_0 terminase GpA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 468.0
TH1_k127_522083_1 Phage portal protein, lambda family - - - 0.000000000000001471 84.0
TH1_k127_522083_2 - - - - 0.0000000000004376 77.0
TH1_k127_5227368_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.018e-254 791.0
TH1_k127_5227368_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 522.0
TH1_k127_5227368_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 459.0
TH1_k127_5227368_3 Domain of unknown function (DUF4390) - - - 0.0000002631 55.0
TH1_k127_5231581_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 2.721e-249 777.0
TH1_k127_5231581_1 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000000000000000000001603 168.0
TH1_k127_5231581_2 DnaJ molecular chaperone homology domain - - - 0.00000000000000001324 92.0
TH1_k127_5244504_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 7.016e-227 706.0
TH1_k127_5244504_1 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000001133 139.0
TH1_k127_5253323_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 4.002e-219 683.0
TH1_k127_5277614_0 argininosuccinate lyase K01755 - 4.3.2.1 9.471e-230 737.0
TH1_k127_5277614_1 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 325.0
TH1_k127_5277614_2 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 307.0
TH1_k127_5277614_3 PFAM response regulator receiver K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003173 267.0
TH1_k127_5279639_0 cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 8.315e-253 784.0
TH1_k127_5279639_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 568.0
TH1_k127_5279639_2 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 553.0
TH1_k127_5279639_3 Predicted metal-dependent hydrolase K07044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 434.0
TH1_k127_5279639_4 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000001025 235.0
TH1_k127_5279639_5 MarR family - - - 0.0000000000000000000000000000000000000000000000000000000002904 204.0
TH1_k127_5285674_0 Peptidase family C25 - - - 0.0 1132.0
TH1_k127_5285674_1 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000001727 156.0
TH1_k127_5285674_2 Domain of unknown function (DUF4394) - - - 0.000000000000007102 77.0
TH1_k127_5286685_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 7.293e-206 673.0
TH1_k127_5286685_1 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000000004838 208.0
TH1_k127_5294287_0 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 431.0
TH1_k127_5294287_1 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 311.0
TH1_k127_5294287_2 Protein of unknown function (DUF2788) - - - 0.00000000000000003556 81.0
TH1_k127_5325050_0 Polyhydroxyalkanoate depolymerase, intracellular K05973 - 3.1.1.75 9.024e-249 771.0
TH1_k127_5325050_1 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 327.0
TH1_k127_5325050_2 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.000000000000000000000000000000000000312 151.0
TH1_k127_5343156_0 Papain family cysteine protease - - - 0.0 1174.0
TH1_k127_5343156_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 602.0
TH1_k127_5343156_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 285.0
TH1_k127_5343156_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000001716 235.0
TH1_k127_5343156_4 ABC-type phosphate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000001766 177.0
TH1_k127_5343156_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0001682 46.0
TH1_k127_5343808_0 Zinc-binding domain of primase-helicase K06919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 591.0
TH1_k127_5343808_1 - - - - 0.00000000000000000000000000000000000000000000000000000000006999 205.0
TH1_k127_5362474_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 6.296e-214 666.0
TH1_k127_5362474_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 321.0
TH1_k127_5362474_2 - - - - 0.00000000000000000000000000000000000000000987 171.0
TH1_k127_5362474_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000004271 156.0
TH1_k127_5362474_4 - - - - 0.000000000000000000000000000000000000001804 163.0
TH1_k127_536441_0 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 372.0
TH1_k127_536441_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 330.0
TH1_k127_536441_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 289.0
TH1_k127_536441_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000001596 143.0
TH1_k127_536441_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000872 132.0
TH1_k127_5367687_0 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 370.0
TH1_k127_5367687_1 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 359.0
TH1_k127_5367687_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003112 277.0
TH1_k127_5367687_3 CRS1_YhbY K07574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001741 257.0
TH1_k127_5367687_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000003327 214.0
TH1_k127_5367687_5 Domain of unknown function (DUF4149) - - - 0.000000000000000000000000000000000000000000000001852 179.0
TH1_k127_5370724_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.569e-231 719.0
TH1_k127_5370724_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 2.096e-208 651.0
TH1_k127_5370724_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 533.0
TH1_k127_5370724_3 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 448.0
TH1_k127_5370724_4 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000000000000002472 175.0
TH1_k127_5377077_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1246.0
TH1_k127_5377077_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 503.0
TH1_k127_5377077_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 417.0
TH1_k127_5377077_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 360.0
TH1_k127_5377077_4 Belongs to the skp family K06142 - - 0.00000000000000000000000000000000000000000000000000000000000000000004725 235.0
TH1_k127_5377077_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000002266 232.0
TH1_k127_5377077_6 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000865 181.0
TH1_k127_5381901_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 365.0
TH1_k127_5381901_1 peptidase M48, Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 357.0
TH1_k127_5381901_2 4-oxalocrotonate tautomerase - - - 0.0000000000000000000000000000000000000000249 155.0
TH1_k127_5382455_0 deoxyribodipyrimidine photolyase-related protein K06876 - - 1.88e-271 842.0
TH1_k127_5382455_1 DNA photolyase K01669 - 4.1.99.3 3.479e-224 703.0
TH1_k127_5382455_2 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 554.0
TH1_k127_5382455_3 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 357.0
TH1_k127_5382455_4 Uncharacterized protein conserved in bacteria (DUF2256) - - - 0.000000000000000001448 86.0
TH1_k127_5382455_5 regulatory protein, arsR K22298 - - 0.00002135 48.0
TH1_k127_5386115_0 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 403.0
TH1_k127_5386115_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 374.0
TH1_k127_5386115_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003783 259.0
TH1_k127_5387256_0 GAF domain K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 383.0
TH1_k127_5387256_1 belongs to the aldehyde dehydrogenase family K00138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 309.0
TH1_k127_5415346_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 588.0
TH1_k127_5415346_1 short-chain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 399.0
TH1_k127_5424053_0 AcrB/AcrD/AcrF family K18138 - - 0.0 1117.0
TH1_k127_5424053_1 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 347.0
TH1_k127_5424562_0 PFAM Aminotransferase class I and II K14287 - 2.6.1.88 7.256e-226 703.0
TH1_k127_5424562_1 MreB/Mbl protein K04046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 516.0
TH1_k127_5424562_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 426.0
TH1_k127_5424562_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000001476 134.0
TH1_k127_5431012_0 PFAM HipA domain protein K07154 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004164 271.0
TH1_k127_5431012_1 sequence-specific DNA binding - - - 0.0000000000000000000000000004455 116.0
TH1_k127_5431012_2 Fic/DOC family - - - 0.00000000000000000000341 94.0
TH1_k127_5448260_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 306.0
TH1_k127_5448260_1 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000001527 206.0
TH1_k127_5469728_0 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 415.0
TH1_k127_5469728_1 Ribosome-associated heat shock protein K04762 - - 0.000000000000000000000000000000000000000000000000007904 194.0
TH1_k127_5469728_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000006391 116.0
TH1_k127_5469728_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000008923 53.0
TH1_k127_547074_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 464.0
TH1_k127_547074_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 392.0
TH1_k127_547074_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000162 256.0
TH1_k127_5473881_0 Transport of potassium into the cell K03549 - - 0.0 1065.0
TH1_k127_5473881_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 598.0
TH1_k127_5473881_2 Benzoate membrane transport protein K05782 - - 0.000000005574 58.0
TH1_k127_5475837_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 4.608e-224 716.0
TH1_k127_5475837_1 Heavy metal transport detoxification protein K07213 - - 0.000000000001636 70.0
TH1_k127_5476533_0 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 370.0
TH1_k127_5476533_1 Protein of unknown function (DUF429) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 322.0
TH1_k127_5476751_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1508.0
TH1_k127_5487884_0 Type II secretory pathway, component ExeA K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 317.0
TH1_k127_5510307_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 3.792e-264 832.0
TH1_k127_5510307_1 NMT1-like family K02051,K15576 - - 2.783e-251 781.0
TH1_k127_5510307_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 4.399e-238 741.0
TH1_k127_5510307_3 ATPases associated with a variety of cellular activities K02049,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 469.0
TH1_k127_5510307_4 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 473.0
TH1_k127_5510307_5 Binding-protein-dependent transport system inner membrane component K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 462.0
TH1_k127_5510307_6 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 288.0
TH1_k127_5510307_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005629 260.0
TH1_k127_5510307_8 Protein of unknown function (DUF1348) K09958 - - 0.000000000000000000000000000000000000000000000000000000000002045 214.0
TH1_k127_5510307_9 Alpha beta hydrolase K14731 - 3.1.1.83 0.0000000000000000000000000000000003683 135.0
TH1_k127_5515048_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 0.0 1128.0
TH1_k127_5515048_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002412 254.0
TH1_k127_5515048_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000001442 235.0
TH1_k127_5515048_3 ribosome binding - - - 0.0000000000000000000000000000000000000316 154.0
TH1_k127_5515048_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000032 155.0
TH1_k127_5515048_5 Outer membrane efflux protein - - - 0.0000000000000000000002614 100.0
TH1_k127_5515048_7 exodeoxyribonuclease VII activity K03601 - 3.1.11.6 0.00003115 53.0
TH1_k127_5516011_0 Predicted metal-dependent hydrolase K07044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 487.0
TH1_k127_5516011_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 357.0
TH1_k127_5519375_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 8.916e-313 961.0
TH1_k127_5519375_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 524.0
TH1_k127_5519375_2 Belongs to the transcriptional regulatory Fis family K03557 - - 0.00000000000000000000000000000000001151 136.0
TH1_k127_5524700_0 Protein of unknown function (DUF917) K09703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 511.0
TH1_k127_5524700_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 345.0
TH1_k127_5524700_2 Asp Glu hydantoin racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 331.0
TH1_k127_5524700_3 cyclase dehydrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003619 251.0
TH1_k127_5524700_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000006479 101.0
TH1_k127_5524700_5 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000002398 86.0
TH1_k127_5527939_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 1.122e-292 900.0
TH1_k127_5527939_1 chemotaxis sensory transducer K03406,K03776,K05874 - - 0.000000000000000000000000000001186 124.0
TH1_k127_5536338_0 phosphate K03306 - - 2.737e-235 738.0
TH1_k127_5536338_1 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 282.0
TH1_k127_5540349_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 611.0
TH1_k127_5540349_1 His Kinase A (phospho-acceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004517 247.0
TH1_k127_5540349_2 response regulator K22010 - - 0.000000000000006343 76.0
TH1_k127_5548099_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 322.0
TH1_k127_5564286_0 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001472 274.0
TH1_k127_5564286_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000001888 179.0
TH1_k127_5566544_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 575.0
TH1_k127_5566544_1 Transcriptional regulator, LysR family K03576 - - 0.000000000000000000000000000000000000000000000001373 175.0
TH1_k127_5584103_0 UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 570.0
TH1_k127_5584103_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 502.0
TH1_k127_5584103_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 472.0
TH1_k127_5584103_3 - - - - 0.00000000000000000000000000007505 119.0
TH1_k127_5601112_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681,K20455 - 4.2.1.117,4.2.1.3 1.459e-309 951.0
TH1_k127_5601112_1 Belongs to the citrate synthase family K01659 - 2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 361.0
TH1_k127_5605650_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 608.0
TH1_k127_5605650_1 HMGL-like K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 423.0
TH1_k127_5605650_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000002026 87.0
TH1_k127_5612947_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000001302 208.0
TH1_k127_5612947_1 PFAM glycoside hydrolase family 39 K21000 - - 0.00000008064 65.0
TH1_k127_562564_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.646e-217 676.0
TH1_k127_562564_1 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 331.0
TH1_k127_5629862_0 GAF domain K21405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 403.0
TH1_k127_5629862_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 340.0
TH1_k127_5639241_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.0 1198.0
TH1_k127_5639241_1 Acetyl-CoA dehydrogenase C-terminal like K00248 - 1.3.8.1 0.0 1089.0
TH1_k127_5639241_2 Enoyl-CoA hydratase/isomerase K20036 - 4.2.1.155 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 494.0
TH1_k127_5639241_3 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 422.0
TH1_k127_5639241_4 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 396.0
TH1_k127_5639241_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000003785 173.0
TH1_k127_5647695_0 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001909 263.0
TH1_k127_5647695_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002361 228.0
TH1_k127_5647695_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000003183 160.0
TH1_k127_5647695_3 Tautomerase enzyme - - - 0.00000000000000000000000000000000000005544 149.0
TH1_k127_5647695_4 PFAM filamentation induced by cAMP protein Fic - - - 0.00002083 47.0
TH1_k127_5647695_5 YceI-like domain - - - 0.0004217 42.0
TH1_k127_5655480_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1337.0
TH1_k127_5663980_0 histidine kinase HAMP region domain protein K03406,K03776,K05874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 354.0
TH1_k127_5663980_1 Lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 282.0
TH1_k127_5663980_2 Diguanylate cyclase - - - 0.0000009071 61.0
TH1_k127_5666839_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 596.0
TH1_k127_5666839_1 TonB-dependent receptor plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 573.0
TH1_k127_5666839_2 PepSY-associated TM region K00380 - 1.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 436.0
TH1_k127_5666839_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000000000008346 178.0
TH1_k127_5673953_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000001083 96.0
TH1_k127_5687388_0 fatty acid desaturase K00508 - 1.14.19.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 480.0
TH1_k127_5687388_1 fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 442.0
TH1_k127_5687388_2 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.000000000000000000000000000000000000000000000002594 179.0
TH1_k127_5687388_3 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.00000000000000000000000000000000001249 140.0
TH1_k127_5732037_0 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 281.0
TH1_k127_5732037_1 - - - - 0.00004764 52.0
TH1_k127_5747594_0 Belongs to the GARS family K01945 - 6.3.4.13 1.212e-251 779.0
TH1_k127_5747594_1 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 350.0
TH1_k127_5763407_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.0 1031.0
TH1_k127_5763407_1 Molybdate K02018 - - 0.00000000000000000000000000000000001811 144.0
TH1_k127_5763407_2 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000003141 139.0
TH1_k127_5766529_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 6.675e-287 885.0
TH1_k127_5766529_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 424.0
TH1_k127_5766529_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000004449 60.0
TH1_k127_5775710_0 serine dehydratase beta chain K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 612.0
TH1_k127_5775710_1 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 592.0
TH1_k127_5793244_0 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000391 260.0
TH1_k127_5793244_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001233 242.0
TH1_k127_5793244_2 Response regulator, receiver - - - 0.00000000003477 64.0
TH1_k127_5796261_0 Glycosyl transferase, family 2 K12992 - - 0.000000000000000000000000000000000000000000000000000000000000000000008878 244.0
TH1_k127_5796261_1 PFAM glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000005534 180.0
TH1_k127_5796261_2 ADP-glyceromanno-heptose 6-epimerase activity K00067,K01784,K17947 - 1.1.1.133,5.1.3.2,5.1.3.25 0.000000000000000000000000000000000000005222 159.0
TH1_k127_5796261_3 Sugar transferases involved in lipopolysaccharide synthesis K03606,K13656,K20997 - 2.7.8.31 0.000000000000000000000000000000525 124.0
TH1_k127_5818126_0 Fatty acid desaturase K00507 - 1.14.19.1 6.439e-201 631.0
TH1_k127_5818126_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 534.0
TH1_k127_5818126_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000000002295 153.0
TH1_k127_5818126_3 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000000002404 113.0
TH1_k127_5824179_0 Plasmid segregation protein ParM K18640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 316.0
TH1_k127_5824179_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000003364 220.0
TH1_k127_5848485_0 Phosphoribulokinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 550.0
TH1_k127_5848485_1 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 481.0
TH1_k127_5848485_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 329.0
TH1_k127_5848485_3 subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000000000000000000000000001353 151.0
TH1_k127_5884118_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 594.0
TH1_k127_5884118_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 375.0
TH1_k127_5884118_2 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002058 274.0
TH1_k127_588724_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000001611 198.0
TH1_k127_588724_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.000000000000000000000000000007626 134.0
TH1_k127_589846_0 peptidase K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 441.0
TH1_k127_589846_1 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 331.0
TH1_k127_589846_2 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000006646 133.0
TH1_k127_589846_3 - - - - 0.0005045 47.0
TH1_k127_5907495_0 ABC transporter K01990,K13926 - - 0.0 1202.0
TH1_k127_5907495_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 518.0
TH1_k127_5907495_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 445.0
TH1_k127_5907495_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 413.0
TH1_k127_5907495_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000009 182.0
TH1_k127_5907495_5 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0010564,GO:0010948,GO:0031333,GO:0031668,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0033554,GO:0034260,GO:0043086,GO:0043087,GO:0043254,GO:0044087,GO:0044092,GO:0045786,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051302,GO:0051336,GO:0051346,GO:0051716,GO:0051726,GO:0051782,GO:0065007,GO:0065009,GO:0071496,GO:1903664,GO:1903665,GO:2000241,GO:2000242,GO:2000244,GO:2000245 - 0.00003749 48.0
TH1_k127_5909354_0 diguanylate cyclase K13069,K21085 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000001055 259.0
TH1_k127_5909354_1 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000001086 221.0
TH1_k127_5909354_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000005109 105.0
TH1_k127_5909354_3 diguanylate cyclase K13069,K21085 - 2.7.7.65 0.0000000000000000000000165 102.0
TH1_k127_5924510_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 520.0
TH1_k127_5924510_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 349.0
TH1_k127_5924510_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 328.0
TH1_k127_5924510_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004029 247.0
TH1_k127_5924510_4 Domain of unknown function (DUF4845) - - - 0.000000000000000000000000000000000000000325 153.0
TH1_k127_594047_0 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 487.0
TH1_k127_594047_1 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 336.0
TH1_k127_594047_2 Transposase - - - 0.000000000000000000000000000000000000000000000000000000008806 199.0
TH1_k127_594047_3 Integrase, catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000000001374 197.0
TH1_k127_594047_4 transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000008263 186.0
TH1_k127_594047_5 Transcriptional regulator K07734 - - 0.00000000000000000000000000000000000000000000000185 179.0
TH1_k127_594047_6 Protein of unknown function (DUF1153) - - - 0.00000000000000000000000000000000000000000005537 162.0
TH1_k127_594047_7 ImcF-related N-terminal domain K11891 - - 0.00000000000000000000000000000000000009033 160.0
TH1_k127_594047_8 Integrase, catalytic region K07497 - - 0.000000000000000000000000000000004856 130.0
TH1_k127_594047_9 Domain of unknown function (DU1801) - - - 0.000000000000000000003204 97.0
TH1_k127_5946686_0 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 482.0
TH1_k127_5946686_1 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 482.0
TH1_k127_5946686_2 PFAM Ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 447.0
TH1_k127_5946686_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 441.0
TH1_k127_5946686_4 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 320.0
TH1_k127_5946686_5 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000002807 234.0
TH1_k127_5946686_6 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000000000000000000000001903 186.0
TH1_k127_5946686_7 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.0000000000000000000000000000000000000000000003296 170.0
TH1_k127_5946686_8 2-oxopent-4-enoate hydratase activity K02554 - 4.2.1.80 0.00000000000000000000000000001696 127.0
TH1_k127_5953257_0 Protein of unknown function (DUF3616) - - - 2.283e-196 617.0
TH1_k127_5953257_1 - - - - 0.0000000000000000000000000000000000000001421 158.0
TH1_k127_5953257_2 - - - - 0.000000000000000006385 90.0
TH1_k127_5974168_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 306.0
TH1_k127_5974168_1 Ferritin, Dps family protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000003154 216.0
TH1_k127_5975372_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 6.618e-195 612.0
TH1_k127_5975372_1 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000000009977 143.0
TH1_k127_5975372_2 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000002421 60.0
TH1_k127_5985834_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.0 1279.0
TH1_k127_5985834_1 Transcriptional regulator - - - 0.000000000000000000000000000002536 121.0
TH1_k127_5994671_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 0.0 1335.0
TH1_k127_5994671_1 Respiratory nitrate reductase beta C-terminal K00371,K17051 - 1.7.5.1 0.0 1018.0
TH1_k127_5994671_2 Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 416.0
TH1_k127_5994671_3 Nitrate reductase delta subunit K00373 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 302.0
TH1_k127_5994671_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000009355 213.0
TH1_k127_5996126_0 chorismate binding enzyme K01665,K03342 - 2.6.1.85,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 505.0
TH1_k127_6002094_0 RNA-metabolising metallo-beta-lactamase K07576 - - 1.158e-220 691.0
TH1_k127_6002094_1 Helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 503.0
TH1_k127_6002094_2 Bacterial protein of unknown function (DUF898) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 360.0
TH1_k127_6002094_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001991 282.0
TH1_k127_6002094_4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000942 222.0
TH1_k127_6002094_5 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000009824 213.0
TH1_k127_6002094_6 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000000000007469 149.0
TH1_k127_6002094_8 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000005867 80.0
TH1_k127_6023130_0 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 328.0
TH1_k127_6023130_1 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001383 255.0
TH1_k127_6023130_2 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000000000000000000000001621 231.0
TH1_k127_6029828_0 GTP-binding protein K06207 - - 0.0 1164.0
TH1_k127_6029828_1 enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000341 109.0
TH1_k127_6032742_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.643e-272 840.0
TH1_k127_6043466_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.486e-235 734.0
TH1_k127_6043466_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 426.0
TH1_k127_6060605_0 PFAM multicopper oxidase type K22348 - 1.16.3.3 1.072e-299 922.0
TH1_k127_6060605_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 1.062e-252 789.0
TH1_k127_6060605_2 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000007397 234.0
TH1_k127_6060605_3 MerR, DNA binding K19591,K19592 - - 0.0000000000000000000000000000000000000000000000000000000000000003707 226.0
TH1_k127_6060605_4 Protein of unknown function, DUF - - - 0.00000000000000000000000000000000000000000000000000000003033 201.0
TH1_k127_6060605_5 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000952 202.0
TH1_k127_6060605_6 Copper binding periplasmic protein CusF - - - 0.00000000000000000000000000000000000000001001 156.0
TH1_k127_6060605_7 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000015 151.0
TH1_k127_6060605_8 Copper resistance protein K - - - 0.00000000000000000006367 93.0
TH1_k127_6068053_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 7.94e-271 840.0
TH1_k127_6077524_0 Domain of unknown function (DUF4331) - - - 5.433e-260 806.0
TH1_k127_6082585_0 Histidine kinase - - - 0.0 1195.0
TH1_k127_6082585_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 293.0
TH1_k127_6084126_0 dioxygenase K11159 - - 2.858e-217 682.0
TH1_k127_6084126_1 Beta-lactamase superfamily domain - - - 1.334e-211 659.0
TH1_k127_6084126_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 601.0
TH1_k127_6084126_3 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.000000000000000001307 90.0
TH1_k127_6092625_0 DNA topoisomerase III K03169 - 5.99.1.2 2.387e-219 683.0
TH1_k127_6092625_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 552.0
TH1_k127_6092625_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 343.0
TH1_k127_6092625_3 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000002818 160.0
TH1_k127_6092625_4 - - - - 0.00000000000000000000000000000001291 142.0
TH1_k127_6094808_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.959e-231 724.0
TH1_k127_6094808_1 AsmA family K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 295.0
TH1_k127_6107380_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.905e-296 913.0
TH1_k127_6107380_1 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 568.0
TH1_k127_6107380_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 469.0
TH1_k127_6107380_3 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 454.0
TH1_k127_6107380_4 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 442.0
TH1_k127_6107380_5 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 422.0
TH1_k127_6107380_6 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000003504 108.0
TH1_k127_6123581_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000005833 246.0
TH1_k127_6123581_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000007716 154.0
TH1_k127_6123581_2 Histidine kinase - - - 0.0000000000000000000000000000000002382 143.0
TH1_k127_6133511_0 TIGRFAM adhesin HecA family 20-residue repeat (two copies), filamentous hemagglutinin family N-terminal domain K15125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 569.0
TH1_k127_6141221_0 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000013 269.0
TH1_k127_6141221_1 Protein of unknown function (DUF1304) K08987 - - 0.00000000000000000000000000000000000000000000000000002037 190.0
TH1_k127_6141221_3 - - - - 0.0005555 44.0
TH1_k127_6142195_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 606.0
TH1_k127_6142195_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 306.0
TH1_k127_6142195_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000271 282.0
TH1_k127_6142195_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004273 241.0
TH1_k127_6142195_4 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000008281 211.0
TH1_k127_6142195_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000007785 203.0
TH1_k127_6142195_6 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000001926 190.0
TH1_k127_6142195_7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000549 138.0
TH1_k127_614317_0 PFAM virulence protein, SciE type K11898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
TH1_k127_614317_1 This family consists of several bacterial proteins of K11903 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003728 258.0
TH1_k127_614317_2 This family consists of a number of uncharacterised bacterial proteins. The function of this family is K11900 - - 0.00000000000000000000000000000000000000000000000000000004986 196.0
TH1_k127_614317_3 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000007801 144.0
TH1_k127_614897_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 2.892e-282 878.0
TH1_k127_614897_1 Bacterial extracellular solute-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 538.0
TH1_k127_6157659_0 Type II and III secretion system protein K02453 - - 9.827e-236 749.0
TH1_k127_6157659_1 Type II secretion system (T2SS), protein N K02463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 327.0
TH1_k127_6157659_2 PFAM General secretion pathway, M protein K02462 - - 0.000000000000000000000000000000000000000000000002759 178.0
TH1_k127_6157659_3 General secretion pathway K02461 - - 0.000000000000000000000000000000000002472 140.0
TH1_k127_6157659_4 TIGRFAM general secretory pathway protein E K02454 - - 0.0000000005209 61.0
TH1_k127_6163149_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 438.0
TH1_k127_6163149_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003416 245.0
TH1_k127_6169817_1 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.0000000000000000000000000000001093 128.0
TH1_k127_6169817_2 acyl-coA-binding protein - - - 0.000000000000000000004142 93.0
TH1_k127_6169817_3 Ammonium Transporter Family K03320 - - 0.000000000000000006545 83.0
TH1_k127_6176189_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.418e-238 750.0
TH1_k127_6176189_1 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000005584 220.0
TH1_k127_6176189_2 - - - - 0.0000000000000000000000000000000001242 136.0
TH1_k127_6185695_0 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 445.0
TH1_k127_6185695_1 Sensors of blue-light using FAD - - - 0.000000000000000000000000000000000000000000000000000000000000000001225 229.0
TH1_k127_6191743_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 613.0
TH1_k127_6191743_1 Permease, YjgP YjgQ K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 312.0
TH1_k127_6193395_0 Belongs to the 'phage' integrase family - - - 7.045e-198 617.0
TH1_k127_6210888_0 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 419.0
TH1_k127_6210888_1 SdiA-regulated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 346.0
TH1_k127_6210888_2 Lamin Tail Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001188 248.0
TH1_k127_6210888_3 Starvation protein B K03600 - - 0.000000000000000000000000000000000000000000000000000000000000001125 223.0
TH1_k127_6215947_0 transcriptional regulator K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 537.0
TH1_k127_6215947_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000005985 238.0
TH1_k127_6215947_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000062 100.0
TH1_k127_6221503_0 the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 548.0
TH1_k127_6227082_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.625e-204 640.0
TH1_k127_6227082_1 FAD linked oxidases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 507.0
TH1_k127_6227082_2 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 520.0
TH1_k127_6227082_3 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001349 266.0
TH1_k127_6227082_4 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002866 243.0
TH1_k127_6227082_5 Lactoylglutathione lyase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000003004 233.0
TH1_k127_6227082_6 Predicted membrane protein (DUF2069) - - - 0.000000000000000000000001339 120.0
TH1_k127_623813_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.713e-239 749.0
TH1_k127_623813_1 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 451.0
TH1_k127_623813_2 KR domain K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 438.0
TH1_k127_623813_3 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.00000000000000000000000000000000000000000000000007106 191.0
TH1_k127_6248656_0 Putative Na+/H+ antiporter - - - 6.738e-206 646.0
TH1_k127_6248656_1 twitching motility protein K02670 - - 3.002e-194 616.0
TH1_k127_6248656_10 START domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000159 278.0
TH1_k127_6248656_11 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000005193 266.0
TH1_k127_6248656_12 Thioesterase-like superfamily K01075 - 3.1.2.23 0.000000000000000000000000000000000000000000000000000000003423 202.0
TH1_k127_6248656_13 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000008666 186.0
TH1_k127_6248656_14 DNA-binding protein VF530 - - - 0.00000000000000000000000000000000001047 138.0
TH1_k127_6248656_2 Extracellular solute-binding protein K02027,K10227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 533.0
TH1_k127_6248656_3 Esterase-like activity of phytase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 526.0
TH1_k127_6248656_4 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 473.0
TH1_k127_6248656_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 467.0
TH1_k127_6248656_6 Histidine Phosphotransfer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 440.0
TH1_k127_6248656_7 chemotaxis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 419.0
TH1_k127_6248656_8 Fasciclin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 342.0
TH1_k127_6248656_9 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007624 283.0
TH1_k127_6250379_0 PFAM Filamentation induced by cAMP - - - 1.421e-194 616.0
TH1_k127_6250379_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000001321 170.0
TH1_k127_6267088_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 381.0
TH1_k127_6267088_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003271 256.0
TH1_k127_6276439_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0 1052.0
TH1_k127_6276439_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 352.0
TH1_k127_6276439_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000002684 188.0
TH1_k127_6276439_3 Glycosyltransferase like family 2 - - - 0.0000000008354 70.0
TH1_k127_6305046_1 Pyocin activator protein PrtN - - - 0.000000000000000000000000000000638 124.0
TH1_k127_6305046_2 Belongs to the ParB family - - - 0.00000000000000000000000000005422 134.0
TH1_k127_6305046_3 - - - - 0.00000002365 59.0
TH1_k127_6308362_0 COG0642 Signal transduction histidine kinase K11527 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 500.0
TH1_k127_631343_0 histidine kinase, dimerisation and phosphoacceptor region K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000004851 165.0
TH1_k127_631343_1 SMART Transport-associated and nodulation region K04065 - - 0.0000000000000000000000000000000000371 137.0
TH1_k127_631343_2 Protein of unknown function (DUF3309) - - - 0.00000000000000000004628 90.0
TH1_k127_6313676_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 393.0
TH1_k127_6313676_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 370.0
TH1_k127_6313676_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 303.0
TH1_k127_6313676_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008053 261.0
TH1_k127_6313676_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000000000001468 207.0
TH1_k127_6313676_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000000000000000000000005167 120.0
TH1_k127_6323579_0 Predicted membrane protein (DUF2339) - - - 2.91e-258 842.0
TH1_k127_6323579_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 571.0
TH1_k127_6323579_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000002734 234.0
TH1_k127_6323579_3 PFAM peptidase S16 lon domain protein K07157 - - 0.000000000000000000000000000000000000004884 149.0
TH1_k127_6323579_4 Protein of unknown function (DUF3999) - - - 0.000000000000000000000000000009017 136.0
TH1_k127_6330024_0 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 444.0
TH1_k127_6330024_1 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000000001412 213.0
TH1_k127_6338963_0 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 2.296e-305 947.0
TH1_k127_6338963_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 351.0
TH1_k127_6338963_2 Histidine kinase - - - 0.0000000000000000000002402 99.0
TH1_k127_6346282_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 2.171e-274 847.0
TH1_k127_6346282_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 5.265e-266 830.0
TH1_k127_6346282_2 Peptidoglycan polymerase that is essential for cell division K03588 - - 3.223e-216 679.0
TH1_k127_6346282_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 518.0
TH1_k127_6346282_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 260.0
TH1_k127_6346282_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000009748 231.0
TH1_k127_6348621_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1242.0
TH1_k127_6348621_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 478.0
TH1_k127_6348621_2 PFAM Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 292.0
TH1_k127_6348621_3 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000006011 179.0
TH1_k127_6354682_0 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 372.0
TH1_k127_6354682_1 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001059 252.0
TH1_k127_6354682_2 Protein of unknown function (DUF1173) - - - 0.0000000000000000000000000000009064 121.0
TH1_k127_6354682_3 heavy metal translocating P-type ATPase K01534 - 3.6.3.3,3.6.3.5 0.0003014 47.0
TH1_k127_6357439_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 1.978e-210 655.0
TH1_k127_6357439_1 enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 440.0
TH1_k127_6357439_2 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000002249 268.0
TH1_k127_6357439_3 succinylglutamate desuccinylase - - - 0.000000000000000000000000000002142 122.0
TH1_k127_6403281_0 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002735 233.0
TH1_k127_6403281_1 - - - - 0.00000001128 66.0
TH1_k127_6403281_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000002841 50.0
TH1_k127_6404226_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 531.0
TH1_k127_6404226_1 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000001054 207.0
TH1_k127_6404226_2 Glucose / Sorbosone dehydrogenase - - - 0.00000005548 66.0
TH1_k127_6404226_3 Domain of unknown function (DUF4347) - - - 0.000002055 61.0
TH1_k127_6406875_0 Sulfite reductase K00381,K00392 - 1.8.1.2,1.8.7.1 4.973e-315 967.0
TH1_k127_6406875_1 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 492.0
TH1_k127_6410761_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 576.0
TH1_k127_6410761_1 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 378.0
TH1_k127_6410761_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000398 279.0
TH1_k127_6412834_0 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 606.0
TH1_k127_6412834_1 Transcriptional regulator, AraC family K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 533.0
TH1_k127_6412834_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 332.0
TH1_k127_6412834_3 Transcription elongation factor, GreA/GreB, C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004856 276.0
TH1_k127_6412834_4 2OG-Fe(II) oxygenase superfamily K03919 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008198,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016705,GO:0016706,GO:0032451,GO:0033554,GO:0034641,GO:0035510,GO:0035511,GO:0035513,GO:0035515,GO:0035552,GO:0035553,GO:0042245,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043734,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044728,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051213,GO:0051716,GO:0055114,GO:0070579,GO:0070988,GO:0070989,GO:0071704,GO:0080111,GO:0090304,GO:0140098,GO:1901360 1.14.11.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000004688 263.0
TH1_k127_6412834_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007039 259.0
TH1_k127_6412834_6 - - - - 0.0000000000000000000009558 96.0
TH1_k127_6425124_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 293.0
TH1_k127_6425124_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004379 278.0
TH1_k127_6425124_2 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000513 132.0
TH1_k127_6431134_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 404.0
TH1_k127_6440454_0 General secretion pathway K02461 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 448.0
TH1_k127_645142_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 578.0
TH1_k127_645142_1 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 400.0
TH1_k127_645142_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 311.0
TH1_k127_645142_3 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000002036 74.0
TH1_k127_647652_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1444.0
TH1_k127_647652_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 330.0
TH1_k127_6485306_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1e-215 671.0
TH1_k127_6485306_1 acetolactate synthase K01652 - 2.2.1.6 1.014e-194 608.0
TH1_k127_6485306_2 synthase small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 299.0
TH1_k127_650173_0 Extracellular repeat protein, HAF family - - - 0.0000000000000000000000000000000000000001075 164.0
TH1_k127_6504807_0 TIGRFAM general secretory pathway protein E K02454 - - 1.432e-252 784.0
TH1_k127_6504807_1 general secretion pathway protein K02455 - - 0.00000000000000000000000000000000000000001073 155.0
TH1_k127_6504807_2 Type II and III secretion system protein K02453 - - 0.00000000000000000000007884 102.0
TH1_k127_6514281_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 595.0
TH1_k127_6514281_1 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 436.0
TH1_k127_6514281_2 Lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.0000000000000000000000000001411 119.0
TH1_k127_6536683_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 317.0
TH1_k127_6536683_1 Polypeptide-transport-associated domain protein ShlB-type - - - 0.0000000000000000261 89.0
TH1_k127_6539702_0 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000001643 263.0
TH1_k127_6539702_1 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000003094 233.0
TH1_k127_6539702_2 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000001308 155.0
TH1_k127_6539702_3 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000000009481 126.0
TH1_k127_6539702_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000002198 79.0
TH1_k127_6542416_0 enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 556.0
TH1_k127_6542416_1 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 447.0
TH1_k127_6542416_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000371 283.0
TH1_k127_6542416_3 5'-nucleotidase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005323 257.0
TH1_k127_6542416_4 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 K18586 - - 0.0000000000000000000000000000000000000000001363 169.0
TH1_k127_6542416_6 - - - - 0.000001357 52.0
TH1_k127_6543576_0 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 407.0
TH1_k127_6543576_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 312.0
TH1_k127_6543576_2 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000004816 259.0
TH1_k127_6543576_3 Polyhydroxyalkanoate synthesis repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003197 252.0
TH1_k127_6543576_4 - - - - 0.000000000000000000000000000000000000000000008661 167.0
TH1_k127_6543576_5 Major Facilitator Superfamily - - - 0.0000000000000000000000001572 109.0
TH1_k127_6549430_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1737.0
TH1_k127_6549430_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 1.252e-224 700.0
TH1_k127_6549430_2 ABC transporter K06020 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 602.0
TH1_k127_6549430_3 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000000000000000000002144 154.0
TH1_k127_6549430_4 - K11275 - - 0.000000000000000000000000000000000203 139.0
TH1_k127_6568394_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 519.0
TH1_k127_6568394_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005263 250.0
TH1_k127_6568394_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000165 190.0
TH1_k127_6568781_0 5'-nucleotidase, C-terminal domain - - - 1.563e-233 734.0
TH1_k127_6568781_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000008435 121.0
TH1_k127_6568781_2 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000000000000000001779 107.0
TH1_k127_657394_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 343.0
TH1_k127_657394_1 COG3327 Phenylacetic acid-responsive transcriptional repressor K02616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007092 287.0
TH1_k127_658272_0 AFG1-like ATPase K06916 - - 2.369e-215 670.0
TH1_k127_658272_1 Mannan-binding protein - - - 0.00000000000008508 82.0
TH1_k127_6603001_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 8.73e-272 844.0
TH1_k127_6603001_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362,K05297 - 1.18.1.1,1.7.1.15 1.949e-228 712.0
TH1_k127_6614704_0 aminopeptidase N K01256 - 3.4.11.2 0.0 1587.0
TH1_k127_6614704_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000054 108.0
TH1_k127_6614704_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000001348 67.0
TH1_k127_6615331_0 ThiF family K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 376.0
TH1_k127_6615331_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008377 271.0
TH1_k127_6615331_2 - - - - 0.00000000000000007448 80.0
TH1_k127_6615331_3 Belongs to the ompA family K03640 - - 0.00000006579 54.0
TH1_k127_6617185_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 463.0
TH1_k127_6617185_1 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000000000000000005464 229.0
TH1_k127_6617453_0 Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide K01426,K01455 - 3.5.1.4,3.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 578.0
TH1_k127_6617453_1 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 523.0
TH1_k127_6617453_2 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 446.0
TH1_k127_6617453_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 331.0
TH1_k127_6617453_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003347 244.0
TH1_k127_6626257_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009676 409.0
TH1_k127_6626257_1 Major Facilitator Superfamily K07552,K18552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 400.0
TH1_k127_6626257_2 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000000000000004637 145.0
TH1_k127_662874_0 TIGRFAM type VI secretion protein IcmF K11891 - - 2.846e-243 775.0
TH1_k127_662874_1 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 436.0
TH1_k127_662874_2 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.0000000000000000000000000000000001536 143.0
TH1_k127_6640505_0 RHS Repeat - - - 0.0000000000000000000000000000003166 136.0
TH1_k127_6640505_1 ASPIC and UnbV - - - 0.00000000002154 70.0
TH1_k127_664158_0 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 516.0
TH1_k127_664158_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003427 266.0
TH1_k127_6651283_0 protein and some similarities with VgrG protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 440.0
TH1_k127_6651283_1 Phage tail sheath C-terminal domain K06907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001276 299.0
TH1_k127_6651283_2 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001753 252.0
TH1_k127_6651283_3 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000001813 209.0
TH1_k127_6651283_4 homolog of phage Mu protein gp47 - - - 0.0000000000000000000000000000000000000000000009988 192.0
TH1_k127_6651283_5 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000001812 158.0
TH1_k127_6651283_6 Gene 25-like lysozyme K06903 - - 0.0000000000000000000000000000002084 131.0
TH1_k127_6651283_7 Protein of unknown function (DUF4255) - - - 0.0000000000001338 74.0
TH1_k127_6651283_8 - - - - 0.00001752 57.0
TH1_k127_6667630_0 Glycosyltransferase Family 4 K03208 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 427.0
TH1_k127_6667630_1 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000001422 220.0
TH1_k127_6667630_2 colanic acid biosynthesis acetyltransferase wcaF K03818 GO:0003674,GO:0003824,GO:0008374,GO:0016740,GO:0016746,GO:0016747 - 0.000000000000000000000000000000000000000002713 162.0
TH1_k127_6667630_3 - - - - 0.000000000000000000000000000000000000000003536 168.0
TH1_k127_6667630_4 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000008738 145.0
TH1_k127_6682413_0 Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide K01426,K01455 - 3.5.1.4,3.5.1.49 1.502e-221 688.0
TH1_k127_6682413_1 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000005391 203.0
TH1_k127_6682413_2 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000006175 139.0
TH1_k127_669074_0 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 4.942e-207 651.0
TH1_k127_669074_1 - - - - 2.337e-206 650.0
TH1_k127_669074_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 409.0
TH1_k127_669074_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001488 269.0
TH1_k127_669074_4 Luciferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004501 259.0
TH1_k127_669074_5 PFAM ribonuclease H K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000003031 176.0
TH1_k127_669074_6 PFAM heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000000000007855 170.0
TH1_k127_669074_7 SlyX K03745 - - 0.00000000000000000003906 91.0
TH1_k127_669074_8 Acyltransferase family - - - 0.000000000000004247 82.0
TH1_k127_6693106_0 peptidase S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 467.0
TH1_k127_6693106_1 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007987 353.0
TH1_k127_6693106_2 Chalcone isomerase-like - - - 0.00000002945 55.0
TH1_k127_6699310_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 3.898e-270 834.0
TH1_k127_6699310_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001859 279.0
TH1_k127_6699310_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000003239 54.0
TH1_k127_6711179_0 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0 1163.0
TH1_k127_6711179_1 Circularly permuted ATP-grasp type 2 - - - 2.354e-296 913.0
TH1_k127_6711179_2 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 8.364e-278 858.0
TH1_k127_6711179_3 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 587.0
TH1_k127_6711179_4 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 413.0
TH1_k127_6711179_5 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 389.0
TH1_k127_6711179_6 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000000000000000000000006456 225.0
TH1_k127_6711179_7 TIGRFAM diguanylate cyclase (GGDEF) domain K21019 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000003139 213.0
TH1_k127_6711179_8 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000000000000001733 191.0
TH1_k127_6714851_0 TraG-like protein, N-terminal region K12056 - - 0.0 1399.0
TH1_k127_6714851_1 Conjugative relaxosome accessory transposon protein K12072 - - 4.324e-302 928.0
TH1_k127_6714851_2 F plasmid transfer operon protein K12057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 412.0
TH1_k127_6722030_0 Belongs to the DegT DnrJ EryC1 family - - - 3.659e-218 683.0
TH1_k127_6722030_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 562.0
TH1_k127_6722030_2 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 408.0
TH1_k127_6722030_3 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 328.0
TH1_k127_6722030_4 Polysaccharide biosynthesis C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 324.0
TH1_k127_6722030_5 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 294.0
TH1_k127_6722030_6 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000008271 212.0
TH1_k127_672227_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1093.0
TH1_k127_672227_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 404.0
TH1_k127_672227_2 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 289.0
TH1_k127_672227_3 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000000000000000000292 217.0
TH1_k127_6725364_0 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 364.0
TH1_k127_6725364_1 PQ loop repeat K15383 - - 0.00000000000000000000000000000009697 130.0
TH1_k127_6725364_2 lipase activity - - - 0.0000000004533 64.0
TH1_k127_6746384_0 acetylornithine K00821 - 2.6.1.11,2.6.1.17 1.022e-213 674.0
TH1_k127_6746384_1 Protein of unknown function (DUF3579) - - - 0.00000000000000000000000000000000000000000000003007 179.0
TH1_k127_6746384_2 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000000000000000306 151.0
TH1_k127_6759317_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000004248 148.0
TH1_k127_6759317_1 PAAR motif - - - 0.000000000000000000000000000000000006706 144.0
TH1_k127_6761533_0 membrane-associated Zn-dependent proteases 1 K16922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 481.0
TH1_k127_6761533_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 434.0
TH1_k127_6761533_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 322.0
TH1_k127_6775895_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 309.0
TH1_k127_6775895_1 Glycosyl transferase K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000007166 241.0
TH1_k127_6777027_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 339.0
TH1_k127_6777027_1 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.00000000000000000000000000000000000000000000000000000000008702 230.0
TH1_k127_6791825_0 relaxase K12070 - - 6.401e-261 814.0
TH1_k127_6791825_1 Type IV secretion-system coupling protein DNA-binding domain K12071 - - 2.603e-218 680.0
TH1_k127_6796385_0 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 328.0
TH1_k127_6796385_1 AraC family transcriptional regulator - - - 0.0000000165 59.0
TH1_k127_6825003_0 Domain of unknown function (DUF4347) - - - 0.0000000000000000000000000000000000000000000000000006923 203.0
TH1_k127_6825003_1 Domain of unknown function (DUF4347) - - - 0.00000002927 64.0
TH1_k127_6825003_2 COG2931, RTX toxins and related Ca2 -binding proteins K12549,K20276 - - 0.00000004729 66.0
TH1_k127_6842566_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 364.0
TH1_k127_6842566_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000007791 215.0
TH1_k127_686465_0 peptidase M48, Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 436.0
TH1_k127_686465_1 TonB-dependent receptor plug K16090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 357.0
TH1_k127_686465_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000025 136.0
TH1_k127_6868694_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 595.0
TH1_k127_6868694_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001448 250.0
TH1_k127_6870324_0 Belongs to the thiolase family K00626 - 2.3.1.9 6.183e-240 743.0
TH1_k127_6870324_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 487.0
TH1_k127_6870324_2 LysR substrate binding domain K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 433.0
TH1_k127_6870324_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 407.0
TH1_k127_6870324_4 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 350.0
TH1_k127_6870324_5 transcriptional regulator - - - 0.0000000000000000000000000000006549 130.0
TH1_k127_6876162_0 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000000000007362 196.0
TH1_k127_688096_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.877e-297 915.0
TH1_k127_688096_1 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.00000000000000000000000000000000005217 134.0
TH1_k127_688096_2 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.00000000000000000006695 91.0
TH1_k127_6903584_0 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 413.0
TH1_k127_6903584_1 Belongs to the UPF0176 family K07146 - - 0.000000000000000000000000000000000000000000000000000000000000004179 219.0
TH1_k127_6905579_0 chemotaxis K03406,K05874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 520.0
TH1_k127_6905579_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000018 76.0
TH1_k127_6909151_0 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 598.0
TH1_k127_6926291_0 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 477.0
TH1_k127_6926291_1 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 459.0
TH1_k127_6926291_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 437.0
TH1_k127_6926830_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1223.0
TH1_k127_6926830_1 Isocitrate lyase K01637 - 4.1.3.1 1.139e-282 869.0
TH1_k127_6926830_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 7.232e-211 658.0
TH1_k127_6926830_3 Alcohol dehydrogenase GroES-like domain K12957,K13979 - - 1.247e-198 621.0
TH1_k127_6926830_4 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 461.0
TH1_k127_6926830_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 348.0
TH1_k127_6926830_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000000000000004935 220.0
TH1_k127_6926830_7 - - - - 0.0000000000000000000000000000000001101 140.0
TH1_k127_6926830_8 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000000002231 120.0
TH1_k127_6928375_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1238.0
TH1_k127_6939601_0 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 503.0
TH1_k127_6939601_1 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003164 241.0
TH1_k127_6939601_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000002173 158.0
TH1_k127_6939601_3 - - - - 0.000000000000000000000000000000000002546 138.0
TH1_k127_6952166_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 509.0
TH1_k127_6952166_1 Belongs to the Dps family K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002058 274.0
TH1_k127_6952166_2 Uncharacterized protein conserved in bacteria (DUF2325) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000917 243.0
TH1_k127_6952166_3 4 iron, 4 sulfur cluster binding K00176,K00528,K03737,K20449 - 1.18.1.2,1.19.1.1,1.2.7.1,1.2.7.3,1.3.7.1 0.0000000000000000006263 89.0
TH1_k127_6967835_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1673.0
TH1_k127_6967835_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 556.0
TH1_k127_6975379_0 type II secretion system protein K02455,K12278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 509.0
TH1_k127_6975379_1 Prokaryotic N-terminal methylation motif K10924 - - 0.0000000000000000000000000000000001416 139.0
TH1_k127_6975379_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K12276 - - 0.000000000000000000000003548 104.0
TH1_k127_6975379_3 Concanavalin A-like lectin/glucanases superfamily K12287 - - 0.0000000000267 75.0
TH1_k127_6984578_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0 1377.0
TH1_k127_6984578_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 2.367e-313 972.0
TH1_k127_6984578_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 3.192e-228 717.0
TH1_k127_6984578_3 metal-dependent phosphohydrolase HD sub domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 573.0
TH1_k127_6984578_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 495.0
TH1_k127_6984578_5 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 302.0
TH1_k127_6984578_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003294 272.0
TH1_k127_6984578_7 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000001293 253.0
TH1_k127_7001158_0 Universal stress protein - - - 0.00000002491 55.0
TH1_k127_7015691_0 His Kinase A (phosphoacceptor) domain - - - 2.997e-296 917.0
TH1_k127_7015691_1 Urea ABC transporter, urea binding protein K11959 - - 4.29e-242 766.0
TH1_k127_7015691_2 Branched-chain amino acid transport system / permease component K11961 - - 4.753e-217 679.0
TH1_k127_7015691_3 Branched-chain amino acid transport system / permease component K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 515.0
TH1_k127_7015691_4 AAA domain K11962 - - 0.00000000000000000000000000000000000000001006 154.0
TH1_k127_702085_0 Ftsk_gamma K03466 - - 0.0 1044.0
TH1_k127_702085_1 Transcriptional regulator, Crp Fnr family K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 399.0
TH1_k127_702085_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006049 278.0
TH1_k127_702085_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000002581 111.0
TH1_k127_702085_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000009366 52.0
TH1_k127_7023060_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 590.0
TH1_k127_7023060_1 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 358.0
TH1_k127_7023060_2 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000001226 131.0
TH1_k127_7035079_0 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 358.0
TH1_k127_7035079_1 Class II aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003007 271.0
TH1_k127_7035079_2 - - - - 0.00000000000000000000000000000000000000001092 162.0
TH1_k127_7038500_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 390.0
TH1_k127_7038500_1 Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000644 260.0
TH1_k127_7058141_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 528.0
TH1_k127_7058141_1 Chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 510.0
TH1_k127_7058141_2 CobQ/CobB/MinD/ParA nucleotide binding domain K08252,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 387.0
TH1_k127_7058141_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003115 265.0
TH1_k127_708561_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000007413 151.0
TH1_k127_708561_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000002717 162.0
TH1_k127_7096165_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 347.0
TH1_k127_7096165_1 - - - - 0.00000000000000000000000000000000000004858 148.0
TH1_k127_7096165_2 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.000000000000000002148 90.0
TH1_k127_710154_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 1.874e-228 713.0
TH1_k127_710154_1 Belongs to the thiolase family K00626 - 2.3.1.9 3.052e-213 669.0
TH1_k127_710154_2 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000009595 179.0
TH1_k127_710154_3 Bacterial-like globin K06886 - - 0.000000000000000000000000000008756 119.0
TH1_k127_7101543_0 AAA domain - - - 4.708e-213 677.0
TH1_k127_7101543_1 SEFIR domain - - - 0.0000000000000000001877 95.0
TH1_k127_7102178_0 Double sensory domain of two-component sensor kinase - - - 2.362e-229 715.0
TH1_k127_7102178_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000004168 158.0
TH1_k127_7102178_2 PFAM Thioredoxin K00384 - 1.8.1.9 0.00000000000000000000005835 109.0
TH1_k127_7104840_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 546.0
TH1_k127_7104840_1 Protein of unknown function (DUF2726) - - - 0.00000000000000000000000000000000000000000000000004536 187.0
TH1_k127_7104840_2 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000003372 134.0
TH1_k127_71148_0 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 473.0
TH1_k127_71148_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 385.0
TH1_k127_71148_2 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 373.0
TH1_k127_71148_3 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000001853 118.0
TH1_k127_711623_0 RHS Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 599.0
TH1_k127_711623_1 PFAM chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 541.0
TH1_k127_7144223_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000001658 200.0
TH1_k127_7144223_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000844 204.0
TH1_k127_7172506_0 NMT1-like family K02051,K15576,K22067 - - 1.291e-241 753.0
TH1_k127_7172506_1 PFAM Cl- channel voltage-gated family protein - - - 4.056e-206 651.0
TH1_k127_7172506_2 Nitrate ABC transporter K15552,K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 494.0
TH1_k127_7172506_3 ATPases associated with a variety of cellular activities K02049,K15578 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 475.0
TH1_k127_7172506_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 426.0
TH1_k127_7172506_5 ANTAR K07183 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 354.0
TH1_k127_7172506_6 MarR family - - - 0.00000000000000000000000000000000000000000000000000008672 190.0
TH1_k127_7172506_7 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000003166 92.0
TH1_k127_7179981_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K12276 - - 2.793e-293 907.0
TH1_k127_7179981_1 TIGRFAM pilus (MSHA type) biogenesis protein MshL K02453,K12282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 371.0
TH1_k127_7187496_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 472.0
TH1_k127_7187496_1 transporter component K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000887 218.0
TH1_k127_7187496_2 transporter component K07112 - - 0.00000000000000000000000000000000000000000000000000000002636 207.0
TH1_k127_7187496_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000004035 154.0
TH1_k127_7191772_0 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 302.0
TH1_k127_7191772_1 Aminotransferase class I and II K00639 - 2.3.1.29 0.0000000000000000000000000001387 120.0
TH1_k127_7198577_0 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000001034 218.0
TH1_k127_7198577_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000000000000000000000000000000000000001127 221.0
TH1_k127_7198577_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000001126 117.0
TH1_k127_7207918_0 acyl-CoA dehydrogenase - - - 3.401e-201 634.0
TH1_k127_7207918_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.272e-196 613.0
TH1_k127_7207918_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 324.0
TH1_k127_7207918_3 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002807 234.0
TH1_k127_7207918_4 Cupin K21747 - - 0.00000000000000000000000000000000000000000000000000003357 201.0
TH1_k127_7209906_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.3e-275 856.0
TH1_k127_7209906_1 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase K03606 - - 1.818e-240 747.0
TH1_k127_7209906_2 protein conserved in bacteria K03690 - - 0.0000000000000000000000000000000000000002116 156.0
TH1_k127_7209906_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 0.000000000000000000000000000001848 121.0
TH1_k127_7217963_0 CHASE - - - 0.0 1090.0
TH1_k127_7217963_1 Crp Fnr family - - - 0.00000002041 57.0
TH1_k127_723394_0 TraU protein K12060 - - 2.907e-233 721.0
TH1_k127_723394_1 TIGRFAM Type-F conjugative transfer system pilin assembly protein TrbC, subgroup K12059 - - 0.0000000000000000000000000000000000000000000000000000000000000000004043 238.0
TH1_k127_723394_2 Type-1V conjugative transfer system mating pair stabilisation K12058 - - 0.0000000000000000000000000000000000001872 143.0
TH1_k127_7250568_0 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 475.0
TH1_k127_7250568_1 Glucose sorbosone K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 460.0
TH1_k127_7255447_0 Major Facilitator Superfamily K02575 - - 3.896e-259 803.0
TH1_k127_7255447_1 Major Facilitator Superfamily K02575 - - 9.257e-252 780.0
TH1_k127_7255447_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.0000000000000000000000000000000000006803 145.0
TH1_k127_7258604_0 Allophanate hydrolase subunit 2 K01941 - 6.3.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 538.0
TH1_k127_7258604_1 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 387.0
TH1_k127_7258604_2 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 370.0
TH1_k127_7263645_0 Histidine kinase - - - 7.478e-301 957.0
TH1_k127_7263645_1 metal-dependent phosphohydrolase HD sub domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 521.0
TH1_k127_7263645_2 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 385.0
TH1_k127_7263645_3 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 371.0
TH1_k127_7263645_4 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.0000000000000000000000000000000000000000000000000000000000000003436 222.0
TH1_k127_7263645_5 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.00000000000000000000000000000000000001708 150.0
TH1_k127_7263645_6 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000003242 129.0
TH1_k127_7263645_7 PFAM Negative transcriptional regulator K07734 - - 0.00000000000000000000591 94.0
TH1_k127_7263645_8 - - - - 0.00000000000000000003763 97.0
TH1_k127_7270542_0 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 580.0
TH1_k127_7270542_1 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.0000000000000000000000000000000000000000002818 160.0
TH1_k127_7270542_2 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.000000000000000000001032 96.0
TH1_k127_7279237_0 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K04090 - 1.2.7.8 9.087e-290 906.0
TH1_k127_7292221_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 447.0
TH1_k127_7292221_1 Diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000000000233 159.0
TH1_k127_7309608_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 559.0
TH1_k127_7309608_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 463.0
TH1_k127_7309608_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 364.0
TH1_k127_7309608_3 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000002773 225.0
TH1_k127_7309608_4 PRC-barrel domain - - - 0.00000000000000000000000000000000000000000000000000000000000001034 218.0
TH1_k127_7340128_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.603e-221 704.0
TH1_k127_7340128_1 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 609.0
TH1_k127_7340128_2 lytic transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 614.0
TH1_k127_7340128_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 437.0
TH1_k127_7340128_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 312.0
TH1_k127_7340128_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004171 272.0
TH1_k127_7340128_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001073 265.0
TH1_k127_7340128_7 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003637 242.0
TH1_k127_7340128_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000000002212 192.0
TH1_k127_7340244_0 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 451.0
TH1_k127_7340244_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000004598 190.0
TH1_k127_7340574_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 3.685e-233 727.0
TH1_k127_7344240_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1267.0
TH1_k127_7344240_1 Flavin-binding monooxygenase-like K07222 - - 1.746e-254 792.0
TH1_k127_7344240_2 Fatty acid desaturase K00496 - 1.14.15.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 563.0
TH1_k127_7344240_3 Alpha beta hydrolase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 438.0
TH1_k127_7344240_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 421.0
TH1_k127_7344240_5 Belongs to the UPF0176 family K07146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 372.0
TH1_k127_7344240_6 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 338.0
TH1_k127_7344240_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 309.0
TH1_k127_7344240_8 Alpha beta hydrolase - - - 0.000000131 54.0
TH1_k127_7350312_0 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 555.0
TH1_k127_7350312_1 PFAM porin Gram-negative type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 376.0
TH1_k127_7350312_2 WHG domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 312.0
TH1_k127_7350312_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 299.0
TH1_k127_7350312_4 - K07004 - - 0.00000000000000000000000000000000000000657 168.0
TH1_k127_7360074_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1120.0
TH1_k127_7372454_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 402.0
TH1_k127_7372454_1 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 319.0
TH1_k127_7372454_2 Protein of unknown function (DUF3485) - - - 0.0000000000000000000000000000000000000000000000000000000002645 211.0
TH1_k127_737768_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 508.0
TH1_k127_737768_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 334.0
TH1_k127_737768_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000189 286.0
TH1_k127_7391717_0 Threonine synthase K01733 - 4.2.3.1 2.795e-270 838.0
TH1_k127_7391717_1 homoserine dehydrogenase K00003 - 1.1.1.3 2.351e-243 756.0
TH1_k127_7391717_2 PFAM aminotransferase, class I and II K14260 - 2.6.1.2,2.6.1.66 4.925e-235 729.0
TH1_k127_7391717_3 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 447.0
TH1_k127_7391717_4 Molybdopterin biosynthesis MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000001309 196.0
TH1_k127_7391717_5 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000004146 126.0
TH1_k127_7391717_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000008082 98.0
TH1_k127_7403357_0 Type VI secretion K11896 - - 2.037e-280 873.0
TH1_k127_7403357_1 TIGRFAM type VI secretion protein, EvpB VC_A0108 family K11900 - - 7.981e-267 827.0
TH1_k127_7403357_2 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.000000000000000000000000000000000000000000000000000000000000000000005272 236.0
TH1_k127_7403357_3 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000000000000000000000000000000000000000000003306 201.0
TH1_k127_7403357_4 TIGRFAM type VI secretion system lysozyme-related protein K11897 - - 0.0000000000000000000000000000000002256 137.0
TH1_k127_7403357_5 Type VI secretion protein K11895 - - 0.0000000000000000006464 92.0
TH1_k127_7419723_0 COG2148 Sugar transferases involved in lipopolysaccharide synthesis K20997 - - 0.00000000000000000000000000000000000000000007559 176.0
TH1_k127_7419723_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 - 4.2.1.46,4.2.1.76 0.00000000000001293 77.0
TH1_k127_742131_0 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 490.0
TH1_k127_742131_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009759 449.0
TH1_k127_742131_2 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001434 280.0
TH1_k127_742131_3 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002834 243.0
TH1_k127_742131_4 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000001033 183.0
TH1_k127_742131_5 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000000008543 143.0
TH1_k127_742131_6 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000003156 136.0
TH1_k127_7423671_0 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 410.0
TH1_k127_7423671_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009116 371.0
TH1_k127_7423671_2 Protein of unknown function (DUF541) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002444 246.0
TH1_k127_7423671_3 TIGRFAM phasin family protein - - - 0.000000000000000726 78.0
TH1_k127_7425237_0 Flavin-binding monooxygenase-like - - - 5.021e-283 872.0
TH1_k127_7425237_1 Lytic transglycosylase catalytic K08309 - - 2.178e-250 800.0
TH1_k127_7425237_2 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 504.0
TH1_k127_7425237_3 PFAM OmpW family protein K07275 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003979 269.0
TH1_k127_7425237_4 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000002394 230.0
TH1_k127_7425237_5 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000004961 201.0
TH1_k127_7430085_0 PFAM carboxyl transferase K01969 - 6.4.1.4 2.745e-273 846.0
TH1_k127_7430085_1 PFAM Enoyl-CoA hydratase isomerase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002409 281.0
TH1_k127_7430085_2 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 0.0000000000000000000000000000003771 124.0
TH1_k127_7440803_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1135.0
TH1_k127_7440803_1 GTP-binding signal recognition particle K02404 - - 2.18e-201 643.0
TH1_k127_7440803_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 437.0
TH1_k127_7440803_3 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 356.0
TH1_k127_7440803_4 bacterial-type flagellum organization K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002868 259.0
TH1_k127_7440803_5 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000001208 129.0
TH1_k127_7441562_0 Acetamidase/Formamidase family K01455 - 3.5.1.49 1.504e-272 838.0
TH1_k127_7441562_1 ATPases associated with a variety of cellular activities K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 406.0
TH1_k127_7441562_2 AAA domain K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 319.0
TH1_k127_7441562_4 Putative regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000008438 198.0
TH1_k127_7443969_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 1.166e-235 729.0
TH1_k127_7443969_1 Major Facilitator Superfamily K02575 - - 0.00000000000000006362 79.0
TH1_k127_7464639_0 PFAM AMP-dependent synthetase and ligase K00666 - - 2.87e-322 998.0
TH1_k127_7464639_1 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 2.685e-243 759.0
TH1_k127_7464639_2 PFAM Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 401.0
TH1_k127_7464639_3 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000001518 144.0
TH1_k127_7464639_4 S4 domain K14761 - - 0.000000000000000000000000001083 114.0
TH1_k127_7464639_5 - - - - 0.0000000000000000002048 93.0
TH1_k127_7468479_0 TonB-dependent receptor plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 420.0
TH1_k127_7468479_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 302.0
TH1_k127_7491266_0 Member of a two-component regulatory system K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 537.0
TH1_k127_7491266_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 389.0
TH1_k127_7491266_2 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 351.0
TH1_k127_7491266_3 Protein of unknown function (DUF2933) - - - 0.0000000000000000003346 90.0
TH1_k127_7505214_0 Type IV pili methyl-accepting chemotaxis transducer N-term K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009989 452.0
TH1_k127_7505214_1 CheW-like domain K02659 - - 0.0000000000000000000000000000000000000000000000000000000000000000003735 233.0
TH1_k127_7505214_2 PFAM response regulator receiver K02658 - - 0.000000000000000000000000000000000000000000000000000000000000000008522 225.0
TH1_k127_7505214_3 cheY-homologous receiver domain K02657 - - 0.000000000000000000000000000000000000000000000000000000000000000009922 227.0
TH1_k127_7508330_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 1.538e-230 716.0
TH1_k127_7508330_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 454.0
TH1_k127_7508330_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 289.0
TH1_k127_7514505_0 Dolichyl-phosphate-mannose-protein mannosyltransferase K00721,K00786 - 2.4.1.83 4.82e-216 685.0
TH1_k127_7514505_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 471.0
TH1_k127_7514505_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 307.0
TH1_k127_7514505_3 PAP2 superfamily - - - 0.0000000000000000000000000000000000186 145.0
TH1_k127_7514505_4 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000002577 106.0
TH1_k127_7523104_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001448 226.0
TH1_k127_7523104_1 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000002148 192.0
TH1_k127_7523104_2 Cupin domain - - - 0.00000000000000000000000000000000000000004555 156.0
TH1_k127_7523104_3 addiction module antidote protein - - - 0.0000000000000000000000000000000000000002471 152.0
TH1_k127_7523104_4 addiction module killer protein - - - 0.0000000000000000000000000000001374 126.0
TH1_k127_7524817_0 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 351.0
TH1_k127_7524817_1 Protein of unknown function (DUF3833) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003922 266.0
TH1_k127_7548628_0 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 536.0
TH1_k127_7548628_1 Type IV Pilus-assembly protein W K02672 - - 0.0000000000004651 76.0
TH1_k127_7548678_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000002996 127.0
TH1_k127_7552076_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 6.967e-205 644.0
TH1_k127_7552076_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000009125 251.0
TH1_k127_7552076_2 peptidylprolyl isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000007266 249.0
TH1_k127_7552076_3 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000013 179.0
TH1_k127_7557190_0 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 385.0
TH1_k127_7557190_1 TraE protein K12067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 369.0
TH1_k127_7557190_2 TraL protein K12068 - - 0.00000000000000000000000000000000000000000000000000000000000001805 215.0
TH1_k127_7557190_3 - - - - 0.00000000000000000000000000000000000005759 152.0
TH1_k127_7557190_4 TraK protein K12066 - - 0.0000000000000000000000000000001432 127.0
TH1_k127_7557190_5 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000004353 59.0
TH1_k127_756745_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 452.0
TH1_k127_756745_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000003887 116.0
TH1_k127_756745_2 Cell wall-associated K13695,K19303 - - 0.000000000000000000000000264 106.0
TH1_k127_7574006_0 Pfam:HxxPF_rpt - - - 0.000000000000000000000000000000000000000000000000000000000000000000365 237.0
TH1_k127_7574006_1 transferase activity, transferring glycosyl groups - - - 0.000000000000005075 87.0
TH1_k127_757446_0 Domain of unknown function (DUF4172) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 527.0
TH1_k127_757446_1 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 434.0
TH1_k127_757446_2 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000001318 186.0
TH1_k127_7575572_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 4.37e-294 912.0
TH1_k127_7575572_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000001834 197.0
TH1_k127_7575572_2 Belongs to the frataxin family K06202 - - 0.0000000000000000000000000000000000000000002255 160.0
TH1_k127_7606992_0 surface antigen K07278 - - 7.769e-214 678.0
TH1_k127_7606992_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000002373 67.0
TH1_k127_7621428_0 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 561.0
TH1_k127_7621428_1 Belongs to the citrate synthase family K01659 - 2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 287.0
TH1_k127_7621441_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0 1047.0
TH1_k127_7621441_1 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 347.0
TH1_k127_7621441_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000001237 218.0
TH1_k127_7621441_3 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000004519 199.0
TH1_k127_7621441_4 - - - - 0.00000000002462 67.0
TH1_k127_7623161_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 3.694e-286 883.0
TH1_k127_7623161_1 PFAM SNF2-related protein - - - 2.728e-259 842.0
TH1_k127_7623161_2 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 537.0
TH1_k127_7623161_3 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 505.0
TH1_k127_7623161_4 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 350.0
TH1_k127_7623161_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000001069 115.0
TH1_k127_7623161_6 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0004631 45.0
TH1_k127_7649685_0 Major Facilitator Superfamily K08159,K19577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 518.0
TH1_k127_7649685_1 Virulence factor membrane-bound polymerase, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 475.0
TH1_k127_7649685_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000004189 102.0
TH1_k127_7689053_0 DNA alkylation repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 528.0
TH1_k127_7689053_1 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 425.0
TH1_k127_7689053_2 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 417.0
TH1_k127_7689053_3 Aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 307.0
TH1_k127_7689053_4 Protein of unknown function (DUF779) K09959 - - 0.0000000000000000000000000000000000000000000000000000003554 196.0
TH1_k127_7689053_5 Belongs to the ArsC family K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000001669 193.0
TH1_k127_7689053_6 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000001107 88.0
TH1_k127_7694677_0 PFAM Polysaccharide deacetylase K01452 - 3.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 546.0
TH1_k127_7694677_1 OHCU decarboxylase K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 440.0
TH1_k127_7694677_2 FCD - - - 0.0000000000000000000000005871 106.0
TH1_k127_7694787_0 Filamentous haemagglutinin family outer membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000001016 229.0
TH1_k127_7701358_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 3.899e-271 848.0
TH1_k127_7701358_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 413.0
TH1_k127_7701358_2 PFAM SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 341.0
TH1_k127_7701358_3 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 345.0
TH1_k127_7701358_4 drug resistance K07552 - - 0.00000001424 59.0
TH1_k127_7706259_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1117.0
TH1_k127_7706259_1 PFAM Aminotransferase class I and II K00832 - 2.6.1.57 2.395e-245 759.0
TH1_k127_7706259_2 Bacterial protein of unknown function (DUF839) K07093 - - 0.0004591 45.0
TH1_k127_7712692_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 556.0
TH1_k127_7712692_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 424.0
TH1_k127_7712692_2 branched-chain amino acid K01999 - - 0.000000000000001175 76.0
TH1_k127_7716780_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 421.0
TH1_k127_7716780_1 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001485 278.0
TH1_k127_7716780_2 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000001706 227.0
TH1_k127_7716780_3 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000004714 184.0
TH1_k127_7716780_4 Flagellar protein FliT K02423 - - 0.000000000001162 68.0
TH1_k127_7718794_0 This family consists of a number of uncharacterised bacterial proteins. The function of this family is K11900 - - 7.587e-239 746.0
TH1_k127_7718794_1 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 287.0
TH1_k127_7718794_2 TIGRFAM type VI secretion-associated protein, ImpA family K11902 - - 0.000000000000000000000000000000000000000000000000000000000000002482 231.0
TH1_k127_7718794_3 Large exoproteins involved in heme utilization or adhesion - - - 0.0000000004312 74.0
TH1_k127_772114_0 Ammonium Transporter K03320,K06580 - - 8.176e-202 630.0
TH1_k127_772114_1 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000000000000000000000000000000000001438 187.0
TH1_k127_772114_2 Zeta toxin - - - 0.000000000003384 70.0
TH1_k127_7729503_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000005561 206.0
TH1_k127_7729503_1 Alpha-N-arabinofuranosidase K01209 - 3.2.1.55 0.00000000000000000000000000000000000000000000000000001298 202.0
TH1_k127_7749099_0 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 316.0
TH1_k127_7749099_1 Glutaredoxin - - - 0.000000000000000000000000001586 117.0
TH1_k127_7749099_2 Belongs to the SUA5 family - - - 0.0000000000000000000000007732 105.0
TH1_k127_7795198_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1300.0
TH1_k127_7795198_1 Stage II sporulation protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 388.0
TH1_k127_7795198_2 Uncharacterized protein conserved in bacteria (DUF2135) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003325 250.0
TH1_k127_7795198_3 Protein of unknown function (DUF1175) K09934 - - 0.0000000000000000000000000000000000000000000000000000000000000001274 229.0
TH1_k127_7795198_4 Uncharacterized protein conserved in bacteria (DUF2135) - - - 0.000001924 54.0
TH1_k127_7795373_0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 431.0
TH1_k127_7795373_1 TIGRFAM type VI secretion lipoprotein, VC_A0113 family K11906 - - 0.0000000000000000000000000000000000000000000000000000000002434 212.0
TH1_k127_7795373_2 COG0457 FOG TPR repeat - - - 0.000000000000000000000000002273 121.0
TH1_k127_7807979_0 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 455.0
TH1_k127_7807979_1 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 452.0
TH1_k127_7807979_2 Cytochrome C assembly protein - - - 0.0000000000000000002298 88.0
TH1_k127_7809649_0 Protein of unknown function (DUF3683) - - - 0.0 2445.0
TH1_k127_7809649_1 Histidine kinase K03407 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.0 1087.0
TH1_k127_7809649_2 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 597.0
TH1_k127_7809649_3 luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 323.0
TH1_k127_7809649_4 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 289.0
TH1_k127_7809649_5 HIT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001077 242.0
TH1_k127_7809649_6 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000001975 225.0
TH1_k127_7809649_7 Cache_2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000568 228.0
TH1_k127_7809649_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000007166 213.0
TH1_k127_7810770_0 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 400.0
TH1_k127_7810770_1 Response regulator receiver K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000007865 227.0
TH1_k127_783302_0 ABC transporter K06158 - - 5.298e-300 932.0
TH1_k127_783302_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 7.231e-221 688.0
TH1_k127_783302_2 twitching motility protein K02670 - - 3.468e-212 665.0
TH1_k127_783302_3 Belongs to the protein N5-glutamine methyltransferase family K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 459.0
TH1_k127_783302_4 Cell wall-associated K13695,K19303 - - 0.00000000000000000000000000000000001409 141.0
TH1_k127_7856902_0 Major facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 560.0
TH1_k127_7856902_1 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 385.0
TH1_k127_7856902_2 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 365.0
TH1_k127_7856902_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 353.0
TH1_k127_7856902_4 PFAM YaeQ - - - 0.0000000000000005216 78.0
TH1_k127_7874444_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 384.0
TH1_k127_7874444_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000003116 173.0
TH1_k127_7874444_2 O-Antigen ligase - - - 0.0000000000000000000000000007258 121.0
TH1_k127_7874444_3 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000502 88.0
TH1_k127_7893747_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 6.328e-235 730.0
TH1_k127_79091_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 4.532e-237 741.0
TH1_k127_79091_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 309.0
TH1_k127_7909599_0 - - - - 0.0000000000000000000000000000000000000000000000000142 197.0
TH1_k127_7911162_0 AMP-binding enzyme C-terminal domain K18661 - - 1.915e-229 720.0
TH1_k127_7911162_1 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.000002897 49.0
TH1_k127_7938583_0 Protein of unknown function (DUF1631) - - - 1.549e-204 646.0
TH1_k127_7938583_1 Pilus assembly protein K12279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 393.0
TH1_k127_7938583_2 TIGRFAM pilus (MSHA type) biogenesis protein MshL K02453,K12282 - - 0.00000000000000000000000000000000000000000000000000001134 199.0
TH1_k127_7938583_3 carbon utilization K12280 - - 0.00000000000000000000000000000000000000000000000158 181.0
TH1_k127_7938583_4 - K12281 - - 0.0001873 50.0
TH1_k127_7963696_0 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 389.0
TH1_k127_7963696_1 Nucleotidyltransferase K09962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 293.0
TH1_k127_7963696_2 pathogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000884 223.0
TH1_k127_7963696_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.000000000000000000000000000000000000000000000002974 175.0
TH1_k127_7963696_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000000000000001134 163.0
TH1_k127_7963696_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000001147 158.0
TH1_k127_7963696_6 Protein of unknown function (DUF1272) K09984 - - 0.0000000000000000000000000000000000000481 143.0
TH1_k127_7963696_7 protein conserved in bacteria - - - 0.000003222 49.0
TH1_k127_7968571_0 RNB K01147 - 3.1.13.1 5.894e-240 747.0
TH1_k127_7968571_1 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007179 280.0
TH1_k127_7968571_2 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000006797 158.0
TH1_k127_7968571_3 Integrin alpha (beta-propellor repeats). - - - 0.0000002042 64.0
TH1_k127_7973780_0 GH3 auxin-responsive promoter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 556.0
TH1_k127_7973780_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005192 231.0
TH1_k127_7974407_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 526.0
TH1_k127_7974407_1 VanZ like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 439.0
TH1_k127_7974407_2 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001692 265.0
TH1_k127_7974407_3 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000000003631 230.0
TH1_k127_7974407_4 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000001468 201.0
TH1_k127_7974407_5 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000004776 130.0
TH1_k127_7974407_6 Belongs to the UPF0250 family K09158 - - 0.000000000000000000000000000003225 122.0
TH1_k127_7974407_7 preprotein translocase K03210 - - 0.000000000002844 67.0
TH1_k127_7976511_0 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily K01002 - 2.7.8.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 600.0
TH1_k127_7976511_1 chemotaxis sensory transducer K03406,K03776,K05874 - - 0.000000000000000000000000000000000002713 144.0
TH1_k127_7984286_0 HD domain - - - 1.987e-262 835.0
TH1_k127_8013163_0 type VI secretion protein K11891 - - 0.0 1485.0
TH1_k127_8029876_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 6.06e-295 929.0
TH1_k127_8029876_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 305.0
TH1_k127_8029876_3 cyclic-guanylate-specific phosphodiesterase activity - - - 0.000000000000000000101 92.0
TH1_k127_8039327_0 VWA domain containing CoxE-like protein K09989 - - 2.026e-222 695.0
TH1_k127_8039327_1 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 519.0
TH1_k127_8039327_2 cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 291.0
TH1_k127_8039327_3 TIGRFAM diguanylate cyclase K13069,K21085 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000004362 202.0
TH1_k127_8039327_4 TIGRFAM outer membrane adhesin like proteiin - - - 0.00000000000000000000000000000000000000000000000003917 185.0
TH1_k127_8050652_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 314.0
TH1_k127_8050677_0 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 478.0
TH1_k127_8050677_1 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001328 282.0
TH1_k127_8053371_0 Fatty acid desaturase K00496 - 1.14.15.3 1.37e-204 642.0
TH1_k127_8053371_1 Glutathione S-transferase, C-terminal domain K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 520.0
TH1_k127_8053371_2 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 459.0
TH1_k127_8053371_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 462.0
TH1_k127_8053371_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 359.0
TH1_k127_8053371_5 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000004382 185.0
TH1_k127_8053371_6 - - - - 0.000000000000000000000000000001915 126.0
TH1_k127_8053371_7 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000006995 112.0
TH1_k127_8061362_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 434.0
TH1_k127_8061362_1 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 377.0
TH1_k127_8061362_2 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 321.0
TH1_k127_8061362_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 293.0
TH1_k127_8061362_4 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000009138 225.0
TH1_k127_8061362_5 pilus assembly K02676 - - 0.00000000000000000000000000000000000000000000000000000000004062 210.0
TH1_k127_8061362_6 Domain of unknown function (DUF4936) - - - 0.000000000003405 71.0
TH1_k127_8061362_7 Transport and Golgi organisation 2 - - - 0.00000001711 55.0
TH1_k127_807364_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 501.0
TH1_k127_807364_1 ABC-type Fe3 transport system, permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 497.0
TH1_k127_807364_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 465.0
TH1_k127_8087465_0 heavy metal translocating P-type ATPase K01534 - 3.6.3.3,3.6.3.5 0.0 1115.0
TH1_k127_8087465_1 - - - - 0.00000000003637 68.0
TH1_k127_8095787_0 MMPL family K18138,K18902 - - 0.0 1637.0
TH1_k127_8095787_1 Outer membrane efflux protein K18903 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 407.0
TH1_k127_8095787_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007528 298.0
TH1_k127_8099863_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.661e-308 949.0
TH1_k127_8099863_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 6.049e-214 669.0
TH1_k127_8099863_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 493.0
TH1_k127_8099863_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 490.0
TH1_k127_8099863_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 389.0
TH1_k127_8099863_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000074 258.0
TH1_k127_8099863_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000000000000000005576 231.0
TH1_k127_8099863_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000000000000000001603 228.0
TH1_k127_8101118_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.792e-266 826.0
TH1_k127_8101118_1 Chalcone isomerase-like - - - 0.00000000000000000000000000008979 121.0
TH1_k127_8117233_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000001942 119.0
TH1_k127_8117233_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000006086 103.0
TH1_k127_8148078_0 Belongs to the UPF0246 family K09861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 409.0
TH1_k127_8148078_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 374.0
TH1_k127_8148078_2 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 336.0
TH1_k127_8148078_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 314.0
TH1_k127_8148078_4 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 303.0
TH1_k127_8175885_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 566.0
TH1_k127_8175885_1 Major Facilitator - - - 0.00000000000000000000000000000000000000000206 158.0
TH1_k127_8176588_0 TIGRFAM type IV-A pilus assembly ATPase PilB K02454,K02504,K02652 - - 6.761e-258 805.0
TH1_k127_8176588_1 Type II secretion system K02653 - - 4.579e-208 652.0
TH1_k127_8176588_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 519.0
TH1_k127_8176588_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000006214 120.0
TH1_k127_8220239_1 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009062 269.0
TH1_k127_8220239_2 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000001695 215.0
TH1_k127_8220239_3 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000001795 217.0
TH1_k127_8220239_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000001055 160.0
TH1_k127_8243375_0 ATPase involved in DNA repair K03546 - - 1.359e-262 827.0
TH1_k127_8245387_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 2.844e-213 663.0
TH1_k127_8248185_0 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000003108 273.0
TH1_k127_8248185_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000001504 248.0
TH1_k127_8248185_2 Hit family K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000007233 203.0
TH1_k127_8248185_3 - - - - 0.00000000000000000000000000000506 128.0
TH1_k127_8248185_4 Methyltransferase domain - - - 0.0000000000000000000000001997 116.0
TH1_k127_8250086_0 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 591.0
TH1_k127_8250086_1 Peroxidase K03782 - 1.11.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 389.0
TH1_k127_8250086_2 Membrane - - - 0.00000000000000000000000000000000001184 139.0
TH1_k127_8270003_0 Predicted membrane protein (DUF2306) - - - 3.507e-227 715.0
TH1_k127_8270003_1 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 469.0
TH1_k127_8270003_2 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000002229 206.0
TH1_k127_8270003_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000002777 209.0
TH1_k127_8270796_0 Chain length determinant protein K20998 - - 0.00000000000000000000000000000000000000000000000000000000000881 224.0
TH1_k127_8270796_1 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000001409 207.0
TH1_k127_8270796_2 AAA domain - - - 0.00000715 56.0
TH1_k127_8273892_0 Rhs element Vgr protein K11904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 562.0
TH1_k127_8273892_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 306.0
TH1_k127_8273892_4 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000145 75.0
TH1_k127_8275305_0 Methyltransferase domain - - - 7.922e-204 640.0
TH1_k127_8275305_1 Transcriptional regulatory protein, C terminal K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 334.0
TH1_k127_8275305_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 301.0
TH1_k127_8275305_3 ProQ/FINO family K03607 - - 0.00000000000000000000000000000000000000000001531 176.0
TH1_k127_8275305_4 oxidoreductase K06955 - - 0.000000000000000000000000000000002512 135.0
TH1_k127_8275305_6 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.00003229 52.0
TH1_k127_8282784_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0 1452.0
TH1_k127_8282784_1 Belongs to the UPF0176 family K07146 - - 0.0000000000000000000000000000000002173 136.0
TH1_k127_8294018_0 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 466.0
TH1_k127_8294018_1 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000009314 130.0
TH1_k127_8304275_0 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 380.0
TH1_k127_8304275_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 359.0
TH1_k127_8304275_2 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 327.0
TH1_k127_8304275_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003969 228.0
TH1_k127_8304275_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000002995 197.0
TH1_k127_8304275_5 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000001497 191.0
TH1_k127_8304275_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000001414 174.0
TH1_k127_8304275_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000006314 134.0
TH1_k127_830790_0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 461.0
TH1_k127_830790_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 458.0
TH1_k127_830790_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 444.0
TH1_k127_830790_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 342.0
TH1_k127_830790_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 315.0
TH1_k127_830790_5 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000001231 218.0
TH1_k127_8326411_0 His Kinase A (phosphoacceptor) domain - - - 2.037e-237 741.0
TH1_k127_8335698_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 6.532e-236 732.0
TH1_k127_8335698_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000002231 130.0
TH1_k127_8337797_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 7.9e-248 773.0
TH1_k127_83379_0 Protein of unknown function (DUF808) K09781 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 441.0
TH1_k127_83379_1 Signal transduction histidine kinase K11711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 392.0
TH1_k127_83379_2 response regulator K11712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 304.0
TH1_k127_83379_3 Transporter K11688,K21395 - - 0.000000000000000000000000000000000000001306 149.0
TH1_k127_8338566_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.137e-284 876.0
TH1_k127_8338566_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 1.231e-255 790.0
TH1_k127_8338566_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 569.0
TH1_k127_8366931_0 ABC transporter K15738 - - 6.058e-308 955.0
TH1_k127_8366931_1 Histidine kinase-like ATPases - - - 3.643e-212 677.0
TH1_k127_8366931_2 Benzoate membrane transport protein K05782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 508.0
TH1_k127_8366931_3 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 480.0
TH1_k127_8366931_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000007633 235.0
TH1_k127_8377089_0 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000000000006575 220.0
TH1_k127_8377089_1 Histidine kinase K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000001128 227.0
TH1_k127_8377089_2 BON domain K04065 - - 0.0000000000000000000000000000004435 125.0
TH1_k127_8377089_3 Protein of unknown function (DUF1328) - - - 0.0000000000000000007539 88.0
TH1_k127_8380999_0 glutamine synthetase K01915 - 6.3.1.2 3.009e-272 854.0
TH1_k127_8380999_1 Binding-protein-dependent transport system inner membrane component K02050 - - 9.504e-194 606.0
TH1_k127_8380999_2 NMT1-like family K02051,K15553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 578.0
TH1_k127_8380999_3 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 544.0
TH1_k127_8380999_4 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 454.0
TH1_k127_8380999_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000007494 228.0
TH1_k127_8380999_6 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000000000000000008986 225.0
TH1_k127_8390762_0 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 365.0
TH1_k127_8390762_1 Alpha-N-arabinofuranosidase K01209 - 3.2.1.55 0.000000000000000000008315 98.0
TH1_k127_8390762_2 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000006704 83.0
TH1_k127_8391274_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 2222.0
TH1_k127_8421063_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 6.527e-321 996.0
TH1_k127_8430681_0 restriction modification system DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 324.0
TH1_k127_8430681_1 N-6 DNA Methylase K03427 - 2.1.1.72 0.000000000000000000000000000000000000009785 146.0
TH1_k127_8432559_0 Belongs to the DEAD box helicase family - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 6.05e-228 720.0
TH1_k127_8438377_0 Metal-dependent hydrolase K07044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 477.0
TH1_k127_8438377_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000006667 247.0
TH1_k127_8438377_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000108 207.0
TH1_k127_8438377_3 Cys/Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.0002177 44.0
TH1_k127_8449793_0 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 327.0
TH1_k127_8449793_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 290.0
TH1_k127_8451518_0 FAD dependent oxidoreductase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 597.0
TH1_k127_8451518_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 586.0
TH1_k127_8451518_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 407.0
TH1_k127_8451518_3 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 362.0
TH1_k127_8451518_4 B12 binding domain K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001548 290.0
TH1_k127_8451518_5 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002467 279.0
TH1_k127_8451518_6 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002781 245.0
TH1_k127_8461384_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 4.743e-221 687.0
TH1_k127_8461384_1 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 548.0
TH1_k127_8461384_2 TRAP dicarboxylate transporter, DctM subunit K03299 - - 0.00000000000000000000000000000000000000000000003725 171.0
TH1_k127_8461384_3 - - - - 0.0000000000000000000000000000000000000000000001157 173.0
TH1_k127_8461384_4 Protein of unknown function (DUF454) K09790 - - 0.000000000000000005718 89.0
TH1_k127_8464837_0 RmuC family K09760 - - 2.994e-221 696.0
TH1_k127_8464837_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 547.0
TH1_k127_8464837_2 Protein of unknown function (DUF1571) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001408 252.0
TH1_k127_8464837_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000002205 179.0
TH1_k127_8467672_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 5.287e-321 983.0
TH1_k127_8467672_1 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002452 272.0
TH1_k127_8467672_2 ATPase family associated with various cellular activities (AAA) - - - 0.0000000001615 65.0
TH1_k127_8479060_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 433.0
TH1_k127_8479060_1 Diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 392.0
TH1_k127_8479238_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 8.248e-194 609.0
TH1_k127_8479238_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 389.0
TH1_k127_8479238_2 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 372.0
TH1_k127_8479238_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 366.0
TH1_k127_8483851_0 Neutral/alkaline non-lysosomal ceramidase, C-terminal K12349 - 3.5.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 545.0
TH1_k127_8484609_0 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 484.0
TH1_k127_8484609_1 Filamentous haemagglutinin family outer membrane protein - - - 0.00000000000001017 76.0
TH1_k127_8489918_0 chemotaxis sensory transducer K03406,K03776,K05874 - - 9.756e-224 729.0
TH1_k127_8489918_1 CheA signal transduction histidine kinase K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 582.0
TH1_k127_8511028_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002147 243.0
TH1_k127_8511028_1 - - - - 0.0006343 43.0
TH1_k127_8530068_0 Putative diguanylate phosphodiesterase - - - 1.752e-227 715.0
TH1_k127_8530068_1 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000001347 128.0
TH1_k127_8531035_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 407.0
TH1_k127_8531035_1 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 292.0
TH1_k127_8531035_2 - - - - 0.0000000000000000000000000000000000000164 151.0
TH1_k127_8544898_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00004 - 1.1.1.303,1.1.1.4 1.166e-226 704.0
TH1_k127_8544898_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 356.0
TH1_k127_8544898_2 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 319.0
TH1_k127_8544898_3 sh3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 324.0
TH1_k127_8544898_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000007119 228.0
TH1_k127_8544898_5 Histidine kinase - - - 0.00000000000000000000000000000002233 137.0
TH1_k127_8544898_6 Gram-negative porin - - - 0.00000000000000006911 84.0
TH1_k127_8547837_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1270.0
TH1_k127_8547837_1 Flagellar motor switch K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 582.0
TH1_k127_8547837_2 Role in flagellar biosynthesis K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 402.0
TH1_k127_8547837_3 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 389.0
TH1_k127_8547837_4 Flagellar motor switch protein fliN K02417,K03225 - - 0.00000000000000000000000000000000000000000000000000000000000003654 217.0
TH1_k127_8547837_5 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000000000000000000004072 201.0
TH1_k127_8547837_6 Rhs element Vgr K11904 - - 0.0000000000000000000000000000000000000000000000002252 185.0
TH1_k127_8547837_7 Role in flagellar biosynthesis K02420 - - 0.00000000000000000000000000000000005334 135.0
TH1_k127_8547837_8 Flagellar biosynthesis protein, FliO K02418 - - 0.000000000000000001937 89.0
TH1_k127_8573312_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 548.0
TH1_k127_8573312_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000005075 177.0
TH1_k127_8581789_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 450.0
TH1_k127_8581789_1 RadC-like JAB domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 336.0
TH1_k127_8581789_2 - - - - 0.000000000000000000000000000000000000002855 147.0
TH1_k127_8581789_3 - - - - 0.00000000000003115 76.0
TH1_k127_8588329_0 propionate catabolism operon regulatory protein K02688 - - 3.037e-253 790.0
TH1_k127_859926_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K16872 - 2.3.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 603.0
TH1_k127_859926_1 Bile acid sodium symporter K14347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 509.0
TH1_k127_859926_2 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000216 282.0
TH1_k127_859926_3 - - - - 0.00000000000000000000000000000009792 128.0
TH1_k127_862853_0 Transposase - - - 0.000000000000000000000000000000000004193 149.0
TH1_k127_8631437_0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 326.0
TH1_k127_8631437_1 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000001102 83.0
TH1_k127_8649735_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1417.0
TH1_k127_8649735_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000001469 244.0
TH1_k127_8650122_0 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000004978 243.0
TH1_k127_8650122_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.00000000000000000000000000000000000000000003916 168.0
TH1_k127_8651239_0 fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 518.0
TH1_k127_8651239_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001878 284.0
TH1_k127_8651239_2 Uncharacterized protein conserved in bacteria (DUF2322) - - - 0.00000000000000000000000000000000000000002839 158.0
TH1_k127_8651239_3 Glycosyl transferase K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000426 154.0
TH1_k127_8690457_0 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 414.0
TH1_k127_8690457_1 NADH flavin oxidoreductase NADH oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 377.0
TH1_k127_8690457_2 Protein of unknown function (DUF1415) K09941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001872 258.0
TH1_k127_8690457_3 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002382 240.0
TH1_k127_8690457_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000002397 228.0
TH1_k127_8690457_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000005919 203.0
TH1_k127_8690457_6 MAPEG family - - - 0.00000000000000000000000000000000000000000000000000003827 195.0
TH1_k127_8693663_0 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 465.0
TH1_k127_8693663_1 Flagellar hook-length control protein K02414 - - 0.0000000000000000000000000000000000000000001969 176.0
TH1_k127_8693663_2 flagellar export protein FliJ K02413 - - 0.0000000000000000013 91.0
TH1_k127_8723086_0 membrane protein, terc K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 572.0
TH1_k127_8723086_1 LysR substrate binding domain K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 549.0
TH1_k127_8723086_2 - - - - 0.00000000000000000000000000000000000000000000000000000001055 201.0
TH1_k127_8723086_3 - - - - 0.000000008745 57.0
TH1_k127_8724821_0 TIGRFAM type I secretion system ATPase K12541 - - 2.363e-275 864.0
TH1_k127_8724821_1 Glycosyl transferase family 41 - - - 2.111e-208 658.0
TH1_k127_8731611_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.814e-202 631.0
TH1_k127_8731611_1 Protein conserved in bacteria K09924 - - 0.00000000000000000000000000000000000000000000000001605 188.0
TH1_k127_8731611_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000007409 143.0
TH1_k127_8744246_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000007569 193.0
TH1_k127_8746109_0 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002957 239.0
TH1_k127_8754906_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009982 423.0
TH1_k127_8778764_0 - - - - 0.0000000000007269 76.0
TH1_k127_8778764_1 - - - - 0.00000001773 60.0
TH1_k127_8781570_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 381.0
TH1_k127_8781570_1 chemotaxis protein K03406,K05874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002881 250.0
TH1_k127_8782194_0 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 374.0
TH1_k127_8782194_1 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004369 275.0
TH1_k127_8782194_2 transcriptional regulator - - - 0.0000000000000000000000000000000000004615 142.0
TH1_k127_8782194_3 Histidine kinase K02484 - 2.7.13.3 0.00000000000000006158 86.0
TH1_k127_8792055_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 514.0
TH1_k127_8792055_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002258 275.0
TH1_k127_880752_0 Protein of unknown function (DUF3034) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 415.0
TH1_k127_880752_1 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 391.0
TH1_k127_880752_2 Chloramphenicol acetyltransferase K19271 - 2.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 313.0
TH1_k127_880752_3 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000000000000000000000000000000002904 215.0
TH1_k127_880752_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000001612 135.0
TH1_k127_8817327_0 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 445.0
TH1_k127_8817327_1 FHA domain K07169,K11913 - - 0.000000000000000000000000000000000003156 154.0
TH1_k127_8817327_2 - - - - 0.00000000000000000000008102 105.0
TH1_k127_8821124_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 384.0
TH1_k127_8821124_1 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 333.0
TH1_k127_8821124_2 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 299.0
TH1_k127_8824994_0 Large family of predicted nucleotide-binding domains K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 594.0
TH1_k127_8824994_1 Large family of predicted nucleotide-binding domains K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 328.0
TH1_k127_8824994_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 299.0
TH1_k127_8824994_3 tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001972 273.0
TH1_k127_8824994_4 NADH flavin oxidoreductase NADH oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002429 249.0
TH1_k127_8832085_0 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000002253 208.0
TH1_k127_8832085_2 PFAM 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000002569 77.0
TH1_k127_8846968_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.13e-288 888.0
TH1_k127_8846968_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 417.0
TH1_k127_8846968_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003008 274.0
TH1_k127_8846968_3 Entericidin EcnA/B family - - - 0.000000003413 61.0
TH1_k127_8862250_0 TRAP dicarboxylate transporter, DctM subunit K03299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 551.0
TH1_k127_8862250_1 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005509 246.0
TH1_k127_8862250_2 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000000000000000005431 237.0
TH1_k127_8862250_3 Putative phosphatase (DUF442) - - - 0.00000000000000000000000000000000000000000000000000000000003887 207.0
TH1_k127_8862250_4 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000000000181 135.0
TH1_k127_8862250_5 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000003741 108.0
TH1_k127_8868502_0 type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 541.0
TH1_k127_8868502_1 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000000006265 239.0
TH1_k127_8868502_2 Type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000000002102 171.0
TH1_k127_8868502_3 Type II secretory pathway, pseudopilin - - - 0.0000000000000000000000000000000001087 139.0
TH1_k127_8912019_0 Type III restriction - - - 7.326e-314 975.0
TH1_k127_8912019_1 Haem-degrading K11477 - - 0.00000000000000000000000000000000000000000000005425 173.0
TH1_k127_8912019_2 MazG-like family - - - 0.000000000000000000000000000000000000000008363 159.0
TH1_k127_8912019_3 addiction module antidote protein, CC2985 family K07746 - - 0.0000000000000000000000000000001131 126.0
TH1_k127_8912019_4 Helix-turn-helix domain K15773 - - 0.0000000000000000007561 89.0
TH1_k127_8912019_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000001711 85.0
TH1_k127_8912019_6 Helix-turn-helix domain - - - 0.0000001973 57.0
TH1_k127_8919528_0 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 556.0
TH1_k127_8919528_1 Methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 520.0
TH1_k127_8919528_2 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009779 419.0
TH1_k127_8919528_3 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 364.0
TH1_k127_8919528_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042171,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 367.0
TH1_k127_8919528_5 Cytochrome P450 - - - 0.000000000000000000000000003845 112.0
TH1_k127_8931626_0 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 488.0
TH1_k127_8938166_0 PHB de-polymerase C-terminus K05973 - 3.1.1.75 2.32e-203 645.0
TH1_k127_8938166_1 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 359.0
TH1_k127_8938166_2 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000003753 80.0
TH1_k127_8938644_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1399.0
TH1_k127_8938644_1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000000000001465 196.0
TH1_k127_8938644_2 regulatory protein, MerR - - - 0.00000000000000000000000000000000000000000005804 167.0
TH1_k127_8945315_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 591.0
TH1_k127_8945315_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 357.0
TH1_k127_8945315_2 Belongs to the DEAD box helicase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 302.0
TH1_k127_8945315_3 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000002666 182.0
TH1_k127_8945315_4 - - - - 0.0000000000000000000000000000000000000001263 153.0
TH1_k127_8945315_5 Flagella basal body rod protein - - - 0.0000000000000000006405 91.0
TH1_k127_8945315_6 Protein of unknown function (DUF2185) - - - 0.0000000000000001474 84.0
TH1_k127_8951667_0 homolog of phage Mu protein gp47 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 572.0
TH1_k127_8951667_1 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 567.0
TH1_k127_8951667_10 - K06905 - - 0.000000000000000000000000000000000000000000005334 181.0
TH1_k127_8951667_11 - - - - 0.000000000000005375 88.0
TH1_k127_8951667_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 368.0
TH1_k127_8951667_3 Oxidoreductase FAD-binding domain K11933,K21832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 335.0
TH1_k127_8951667_4 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002404 246.0
TH1_k127_8951667_5 Rhs element vgr protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001609 239.0
TH1_k127_8951667_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000008073 229.0
TH1_k127_8951667_7 photosystem II stabilization - - - 0.000000000000000000000000000000000000000000000000000003107 211.0
TH1_k127_8951667_8 PAAR motif protein - - - 0.00000000000000000000000000000000000000000000000000003658 190.0
TH1_k127_8951667_9 Mu-like prophage protein gp46 - - - 0.0000000000000000000000000000000000000000000000001608 181.0
TH1_k127_8955172_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 619.0
TH1_k127_8955172_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 580.0
TH1_k127_8955172_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 333.0
TH1_k127_8955172_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 338.0
TH1_k127_8955172_4 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000003503 191.0
TH1_k127_8955172_5 - - - - 0.000000000000000000000000000000000000002297 154.0
TH1_k127_8958134_0 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 424.0
TH1_k127_8958134_1 Lipase (class 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 299.0
TH1_k127_8958134_2 rhs element vgr protein K11904 - - 0.0000000000000000000000000000000000000000000759 165.0
TH1_k127_8958134_3 Lysine-specific metallo-endopeptidase - - - 0.00000000000000000000006681 109.0
TH1_k127_8958276_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 293.0
TH1_k127_8958276_1 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003804 267.0
TH1_k127_8958276_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000002517 168.0
TH1_k127_8958276_3 - - - - 0.00000000004444 65.0
TH1_k127_8958447_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008561 434.0
TH1_k127_8958447_1 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 372.0
TH1_k127_8958447_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000006494 248.0
TH1_k127_8958447_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000001212 159.0
TH1_k127_8963018_0 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 566.0
TH1_k127_8963018_1 alpha/beta hydrolase fold K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000001009 252.0
TH1_k127_8972123_0 SNF2 family N-terminal domain - - - 0.0 1091.0
TH1_k127_8972123_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 548.0
TH1_k127_8972123_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000000001006 186.0
TH1_k127_8972123_11 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000000000000000000001075 188.0
TH1_k127_8972123_12 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000000000005302 159.0
TH1_k127_8972123_13 Translation initiation factor K03113 - - 0.0000000000000000000000000000000000000000008043 160.0
TH1_k127_8972123_14 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000000000000002159 146.0
TH1_k127_8972123_15 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000000000000001856 117.0
TH1_k127_8972123_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 543.0
TH1_k127_8972123_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 494.0
TH1_k127_8972123_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 417.0
TH1_k127_8972123_5 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 384.0
TH1_k127_8972123_6 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 296.0
TH1_k127_8972123_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002431 255.0
TH1_k127_8972123_8 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000000000000004367 211.0
TH1_k127_8972123_9 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000000000287 201.0
TH1_k127_8985258_0 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 505.0
TH1_k127_8985258_1 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 476.0
TH1_k127_8985258_2 Gram-negative porin - - - 0.0000000000000000000000000000000001576 145.0
TH1_k127_8993629_0 Nucleotidyl transferase K00992 - 2.7.7.99 3.105e-200 629.0
TH1_k127_8993629_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 524.0
TH1_k127_8993629_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 391.0
TH1_k127_8993629_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 399.0
TH1_k127_8993629_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 320.0
TH1_k127_8993629_5 - - - - 0.00000000000000001231 89.0
TH1_k127_8993629_6 Glycosyltransferase Family 4 - - - 0.00000003088 57.0
TH1_k127_8993903_0 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 445.0
TH1_k127_8993903_1 PFAM Inner membrane CreD family protein K06143 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 424.0
TH1_k127_8993903_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 321.0
TH1_k127_9010561_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 535.0
TH1_k127_9010561_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 460.0
TH1_k127_901519_0 GGDEF domain - - - 3.118e-196 634.0
TH1_k127_901519_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 385.0
TH1_k127_9023271_0 Exonuclease C-terminal K01141 - 3.1.11.1 2.169e-258 801.0
TH1_k127_9023271_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007828 516.0
TH1_k127_9023271_2 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 377.0
TH1_k127_9023271_3 WLM domain K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001646 251.0
TH1_k127_9023271_4 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001748 250.0
TH1_k127_9023271_5 Belongs to the ompA family - - - 0.0000000000000000000000001742 113.0
TH1_k127_9023271_6 pfkB family carbohydrate kinase K16370 - 2.7.1.11 0.0000000000000000002621 89.0
TH1_k127_9070167_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.023e-245 766.0
TH1_k127_9070167_1 TIGRFAM TIGR03790 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 456.0
TH1_k127_9070167_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 406.0
TH1_k127_9070167_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000575 225.0
TH1_k127_9070167_4 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000001789 187.0
TH1_k127_9079597_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.509e-249 772.0
TH1_k127_9079597_1 NnrU protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000482 278.0
TH1_k127_9079597_2 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.00000000000000000000000000000000000000000000000000000732 196.0
TH1_k127_9090348_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 485.0
TH1_k127_9090348_1 Transcriptional regulator, LysR family - - - 0.0000000000000000001093 90.0
TH1_k127_9090348_2 Domain of unknown function (DUF4148) - - - 0.000000006735 63.0
TH1_k127_9123528_0 twitching motility protein K02669,K12203 - - 1.113e-213 666.0
TH1_k127_9123528_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000007671 162.0
TH1_k127_9123528_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000002105 76.0
TH1_k127_9133097_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 358.0
TH1_k127_9133097_1 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 332.0
TH1_k127_9133097_2 Transcriptional regulator K02444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 310.0
TH1_k127_9133097_3 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.00000000000000000000000000000000000000000000000000000000000000002266 240.0
TH1_k127_9133490_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 355.0
TH1_k127_9133490_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001152 244.0
TH1_k127_9179530_0 PFAM ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000001084 243.0
TH1_k127_9179530_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000001508 226.0
TH1_k127_9179862_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 9.243e-298 927.0
TH1_k127_9179862_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 420.0
TH1_k127_9179862_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 304.0
TH1_k127_9179862_3 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004335 268.0
TH1_k127_9179862_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000004346 220.0
TH1_k127_9179862_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000000003097 100.0
TH1_k127_9179862_6 Carboxylesterase family - - - 0.0004054 48.0
TH1_k127_9185608_0 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001126 236.0
TH1_k127_9185608_1 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000001226 222.0
TH1_k127_9185608_2 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000000003495 167.0
TH1_k127_9185608_3 PFAM Class I peptide chain release factor K15034 - - 0.000000000000000000000000000000000000000000002421 171.0
TH1_k127_9185608_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000001579 153.0
TH1_k127_9187359_0 ABC transporter K01990,K13926 - - 3.23e-250 781.0
TH1_k127_9187359_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 537.0
TH1_k127_9187359_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000005299 197.0
TH1_k127_9192022_0 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 468.0
TH1_k127_9192022_1 Secretory lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000003751 231.0
TH1_k127_9192348_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 374.0
TH1_k127_9192348_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus - - - 0.00000000000000000000000000000000000000000000000000000000000000000008397 249.0
TH1_k127_9194348_0 Site-specific recombinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 319.0
TH1_k127_9194348_1 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000000004945 194.0
TH1_k127_9201160_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 361.0
TH1_k127_9201160_1 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 284.0
TH1_k127_9201160_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000009569 235.0
TH1_k127_9201160_3 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000000000002087 203.0
TH1_k127_9201160_4 Belongs to the UPF0434 family K09791 - - 0.00000000000000000001244 93.0
TH1_k127_9209620_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 374.0
TH1_k127_9209620_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000002037 268.0
TH1_k127_9209620_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000008912 161.0
TH1_k127_9224653_0 Transcriptional regulator - - - 7.596e-195 614.0
TH1_k127_9224653_1 2-nitropropane dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 378.0
TH1_k127_9232306_0 TRAP C4-dicarboxylate transport system permease DctM subunit K11690,K21393 - - 2.873e-240 748.0
TH1_k127_9232306_1 Glycine cleavage system T protein K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 379.0
TH1_k127_9232306_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 312.0
TH1_k127_9232306_3 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 306.0
TH1_k127_9232306_4 lysine biosynthetic process via aminoadipic acid K06133 - - 0.000000000000000000001032 104.0
TH1_k127_9242829_0 Haemolysin-type calcium binding protein related domain K01406 - 3.4.24.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 485.0
TH1_k127_9242829_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 386.0
TH1_k127_9242829_2 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 296.0
TH1_k127_9242829_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 292.0
TH1_k127_924531_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 356.0
TH1_k127_924531_1 Cupin K21747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 299.0
TH1_k127_924531_2 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000008861 205.0
TH1_k127_9247404_0 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 492.0
TH1_k127_9247404_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 293.0
TH1_k127_9249455_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 2.565e-228 713.0
TH1_k127_9249455_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 530.0
TH1_k127_9249455_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 407.0
TH1_k127_9249455_3 Sporulation related domain K03749 - - 0.00000000000000000006541 92.0
TH1_k127_9251417_0 general secretion pathway protein K02455 - - 5.049e-199 626.0
TH1_k127_9251417_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007948 274.0
TH1_k127_9251417_2 TIGRFAM general secretory pathway protein E K02454 - - 0.0000000000000000000000000000000000000000000000004788 175.0
TH1_k127_925734_0 twitching motility protein K02670 - - 3.956e-230 715.0
TH1_k127_925734_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 432.0
TH1_k127_925734_2 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006502 249.0
TH1_k127_925734_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000003096 210.0
TH1_k127_925734_4 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000004789 189.0
TH1_k127_925734_5 Belongs to the UPF0102 family K07460 - - 0.0000005263 51.0
TH1_k127_9258257_0 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 414.0
TH1_k127_9258257_1 membrane - - - 0.000000000000000000000000000005094 122.0
TH1_k127_9262401_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.023e-248 770.0
TH1_k127_9262401_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 581.0
TH1_k127_9262401_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 392.0
TH1_k127_9262401_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000319 262.0
TH1_k127_9264680_0 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000003058 192.0
TH1_k127_9264680_1 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000004066 162.0
TH1_k127_9264680_2 Protein of unknown function (DUF3034) - - - 0.000000004856 58.0
TH1_k127_9282556_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1363.0
TH1_k127_9282556_1 acyl-CoA dehydrogenase - - - 8.251e-299 921.0
TH1_k127_9282556_2 Belongs to the thiolase family K00632 - 2.3.1.16 1.113e-230 720.0
TH1_k127_9282556_3 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008395 233.0
TH1_k127_9282556_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000002288 174.0
TH1_k127_9293608_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1091.0
TH1_k127_9293608_1 Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 287.0
TH1_k127_9293608_2 Cytochrome K08738 - - 0.00000000000000000000000000000000003706 137.0
TH1_k127_9293608_3 - - - - 0.0000000000000000000000000000007104 123.0
TH1_k127_930123_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 467.0
TH1_k127_930123_1 tryptophan synthase subunit beta - - - 0.0000000000000000000000000000007671 126.0
TH1_k127_9303581_0 Conserved hypothetical protein 2217 (DUF2460) - - - 0.0000000000000000000000000001593 127.0
TH1_k127_9303581_1 - - - - 0.0000000000000000000000000002493 132.0
TH1_k127_9305776_0 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001542 288.0
TH1_k127_9305776_1 Protein of unknown function (DUF3485) - - - 0.0000000000000000000000000000000000000000000000000006446 192.0
TH1_k127_9307045_0 FAD binding domain K07077 - - 1.849e-240 753.0
TH1_k127_9307045_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 504.0
TH1_k127_9310533_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009546 340.0
TH1_k127_9310533_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001037 223.0
TH1_k127_9334416_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1293.0
TH1_k127_9334416_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.446e-289 889.0
TH1_k127_9334416_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 5.747e-263 811.0
TH1_k127_9334416_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 423.0
TH1_k127_9334416_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 354.0
TH1_k127_9334416_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 338.0
TH1_k127_9334416_6 NADH dehydrogenase K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 288.0
TH1_k127_9334416_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000004197 226.0
TH1_k127_9334416_8 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000000000005274 133.0
TH1_k127_9338540_0 PFAM helicase domain protein - - - 1.162e-285 880.0
TH1_k127_9355053_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 1.51e-267 831.0
TH1_k127_9355053_1 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 436.0
TH1_k127_936574_0 Histidine kinase K07638 - 2.7.13.3 5.461e-247 767.0
TH1_k127_936574_1 PFAM response regulator receiver K02483,K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 467.0
TH1_k127_936574_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001338 271.0
TH1_k127_936574_3 Ammonium Transporter K03320,K06580 - - 0.00000000000000002729 83.0
TH1_k127_9370447_0 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002264 261.0
TH1_k127_9370447_1 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000005412 122.0
TH1_k127_9370447_2 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000006181 90.0
TH1_k127_9380326_0 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 415.0
TH1_k127_9380326_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000002555 223.0
TH1_k127_9380326_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000001941 58.0
TH1_k127_9380709_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2306.0
TH1_k127_9380709_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 383.0
TH1_k127_9387672_0 sulfate ABC transporter K02046,K15496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 496.0
TH1_k127_9387672_1 Binding-protein-dependent transport system inner membrane component K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 457.0
TH1_k127_9387672_2 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.00000000000000000000000000000000000001596 144.0
TH1_k127_9388324_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.137e-239 757.0
TH1_k127_9388324_1 TrkA-N domain K03455 - - 4.603e-207 659.0
TH1_k127_9388324_2 Rhs element Vgr protein K11904 - - 0.000000000000000000000000000000000000000000000000000000000002404 218.0
TH1_k127_9392871_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 445.0
TH1_k127_9392871_1 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 409.0
TH1_k127_9392871_2 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 408.0
TH1_k127_9392871_3 seryl-tRNA synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 388.0
TH1_k127_9392871_4 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000006589 193.0
TH1_k127_9392871_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000004393 93.0
TH1_k127_9392871_7 Phosphopantetheine attachment site - - - 0.0000000000000001415 86.0
TH1_k127_9392871_8 Polysaccharide biosynthesis/export protein K01991 - - 0.0005507 48.0
TH1_k127_9395108_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 541.0
TH1_k127_9395108_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 458.0
TH1_k127_9395108_2 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 414.0
TH1_k127_9395108_3 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001438 252.0
TH1_k127_9395108_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000002368 227.0
TH1_k127_9411326_0 GXWXG protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006968 275.0
TH1_k127_9411326_1 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000009911 160.0
TH1_k127_942381_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K00533,K18006 - 1.12.1.2,1.12.7.2 0.0 1049.0
TH1_k127_942381_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 7.767e-261 812.0
TH1_k127_942381_2 Belongs to the peptidase S16 family - - - 2.893e-224 715.0
TH1_k127_942381_3 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 343.0
TH1_k127_942381_4 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004727 245.0
TH1_k127_942381_5 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000002915 217.0
TH1_k127_942381_6 Protein required for attachment to host cells - - - 0.00000000000000001864 87.0
TH1_k127_9424402_0 Arsenite-activated ATPase (ArsA) K01551 - 3.6.3.16 1.706e-223 698.0
TH1_k127_9424402_1 Poly-beta-hydroxybutyrate polymerase K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 522.0
TH1_k127_9442936_0 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1058.0
TH1_k127_9442936_1 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 312.0
TH1_k127_9443688_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 600.0
TH1_k127_9443688_1 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 327.0
TH1_k127_9443688_2 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 320.0
TH1_k127_9443688_3 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007156 273.0
TH1_k127_9459570_0 Carboxyl transferase domain K13778 - 6.4.1.5 7.592e-300 924.0
TH1_k127_9459570_1 KR domain K13774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 460.0
TH1_k127_9459570_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000688 94.0
TH1_k127_9462964_0 Glycosyltransferase Family 4 - - - 4.26e-196 615.0
TH1_k127_9467844_0 Participates in both transcription termination and antitermination K02600 - - 5.211e-285 879.0
TH1_k127_9467844_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 478.0
TH1_k127_9467844_2 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 397.0
TH1_k127_9467844_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003377 251.0
TH1_k127_9467844_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000000001663 156.0
TH1_k127_9467844_5 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000003336 123.0
TH1_k127_9467844_6 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000004433 103.0
TH1_k127_9473238_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 589.0
TH1_k127_9483573_0 CheA signal transduction histidine kinase K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 288.0
TH1_k127_9483573_1 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000001922 193.0
TH1_k127_9483573_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000002906 106.0
TH1_k127_9483573_3 antisigma factor binding K04749,K06378 - - 0.0000004941 56.0
TH1_k127_9496177_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 2.495e-240 744.0
TH1_k127_9496177_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 426.0
TH1_k127_9496177_2 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 306.0
TH1_k127_9496177_3 Major facilitator superfamily K05939 - 2.3.1.40,6.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000006133 241.0
TH1_k127_9496177_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000002557 171.0
TH1_k127_9499277_0 Rhs element Vgr protein K11904 - - 6.357e-225 720.0
TH1_k127_950211_0 fad dependent oxidoreductase K07137 - - 3.338e-271 839.0
TH1_k127_950211_1 COG3070 Regulator of competence-specific genes K07343 GO:0006810,GO:0007154,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0015931,GO:0030420,GO:0031668,GO:0044764,GO:0050657,GO:0050896,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0051716,GO:0071496,GO:0071702,GO:0071705,GO:0098657 - 0.00000000000000000000005565 107.0
TH1_k127_9528520_0 type II and III secretion system protein K02666 - - 7.295e-268 836.0
TH1_k127_9528520_1 pilus assembly protein PilM K02662 - - 9.127e-207 646.0
TH1_k127_9528520_2 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 310.0
TH1_k127_9528520_3 PFAM Fimbrial assembly family protein K02663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009419 255.0
TH1_k127_9528520_4 pilus assembly protein PilP K02665 - - 0.0000000000000000000000000000000000000000000000000000000001062 209.0
TH1_k127_9533026_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 504.0
TH1_k127_9533026_1 Lysine methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 312.0
TH1_k127_9533026_2 Type II secretory pathway, component ExeA K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000006608 230.0
TH1_k127_9535085_0 PrpF protein K09788 - - 1.168e-223 711.0
TH1_k127_9535085_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681,K20455 - 4.2.1.117,4.2.1.3 1.15e-219 683.0
TH1_k127_9535085_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008866 250.0
TH1_k127_9544614_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 367.0
TH1_k127_9544614_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 353.0
TH1_k127_9544614_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.00000000000000000000000002799 108.0
TH1_k127_9545391_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 515.0
TH1_k127_9545391_1 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004944 267.0
TH1_k127_9545391_2 - - - - 0.0003061 48.0
TH1_k127_9573370_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 3.471e-283 877.0
TH1_k127_9573370_1 PFAM porin Gram-negative type - - - 0.00000000000000000000000000000002163 139.0
TH1_k127_9587109_0 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 468.0
TH1_k127_9587109_1 Bacterial protein of unknown function (DUF934) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004265 233.0
TH1_k127_9587109_2 Sulfite reductase K00381,K00392 - 1.8.1.2,1.8.7.1 0.00000000621 56.0
TH1_k127_9588007_0 Transposase and inactivated derivatives - - - 4.072e-286 884.0
TH1_k127_9588007_1 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 432.0
TH1_k127_9588007_2 Resolvase domain - - - 0.00000000002352 66.0
TH1_k127_9602153_0 branched-chain amino acid K01999 - - 3.852e-211 659.0
TH1_k127_9624446_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 6.439e-225 699.0
TH1_k127_9624446_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 286.0
TH1_k127_9624446_2 Heavy-metal-associated domain K07213 - - 0.00000000000000000000001163 103.0
TH1_k127_9625172_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 579.0
TH1_k127_9625172_1 Polysaccharide biosynthesis C-terminal domain - - - 0.000000000000001413 80.0
TH1_k127_963281_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2178.0
TH1_k127_963281_1 - - - - 0.0001124 47.0
TH1_k127_963613_0 PPIC-type PPIASE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 304.0
TH1_k127_963613_1 Rhomboid family - - - 0.000000000000000000000000002748 116.0
TH1_k127_9660945_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 599.0
TH1_k127_9660945_1 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 373.0
TH1_k127_9660945_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 326.0
TH1_k127_9660945_3 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000002769 167.0
TH1_k127_9674242_0 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 463.0
TH1_k127_9674242_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000005082 197.0
TH1_k127_9674242_2 Thioredoxin-like domain - - - 0.000000000000000000000000000000000000000000000000000001108 198.0
TH1_k127_9693194_0 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K12132 - 2.7.11.1,3.1.3.16 2.593e-251 785.0
TH1_k127_9693194_1 Major Facilitator Superfamily K02575 - - 1.571e-214 671.0
TH1_k127_9693194_2 phosphoesterase, PHP K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 490.0
TH1_k127_9693194_3 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 394.0
TH1_k127_9693194_4 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000001859 183.0
TH1_k127_9693194_5 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000004568 156.0
TH1_k127_9697923_0 Binding-protein-dependent transport system inner membrane component - - - 1.509e-266 831.0
TH1_k127_9697923_1 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 587.0
TH1_k127_9697923_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008647 271.0
TH1_k127_9697923_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003251 258.0
TH1_k127_9697923_4 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000003108 173.0
TH1_k127_9702089_0 Iron-containing alcohol dehydrogenase K00043,K00217 - 1.1.1.61,1.3.1.32 4.819e-219 684.0
TH1_k127_9702089_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000004839 175.0
TH1_k127_97093_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 548.0
TH1_k127_97093_1 Prokaryotic N-terminal methylation motif K12285 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 344.0
TH1_k127_97093_2 Concanavalin A-like lectin/glucanases superfamily K12287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002987 278.0
TH1_k127_97093_3 type IV pilus modification protein PilV K10927 - - 0.0000000000000000000000000000000000000000000000000000006021 197.0
TH1_k127_97093_4 Pilus assembly protein PilX - - - 0.0000000000000000000000000000000000006809 151.0
TH1_k127_97093_5 Tfp pilus assembly protein FimT K10926 - - 0.00000000000000000000000000000000002057 140.0
TH1_k127_9713009_0 Transposase IS66 family K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 426.0
TH1_k127_9713009_1 Transposase IS66 family K07484 - - 0.00000000000000001273 83.0
TH1_k127_9713009_3 IS66 Orf2 like protein K07484 - - 0.00000000002085 69.0
TH1_k127_9713009_4 Transposase IS66 family K07484 - - 0.0000008214 53.0
TH1_k127_978007_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000007467 182.0
TH1_k127_978007_1 homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000001972 141.0
TH1_k127_986283_0 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000000000002331 211.0
TH1_k127_986283_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000001553 169.0
TH1_k127_986283_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.0000000000000000008298 85.0
TH1_k127_986774_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0 1156.0
TH1_k127_986774_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 436.0
TH1_k127_986774_2 Succinate dehydrogenase cytochrome b556 subunit K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000142 256.0
TH1_k127_986774_3 Succinate dehydrogenase hydrophobic membrane anchor protein K00242 - - 0.0000000000000000000000000000000000000000000000000000000000000001663 222.0
TH1_k127_986774_4 UTRA K03710 - - 0.00000007973 53.0
TH1_k127_987031_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 5.043e-219 684.0
TH1_k127_987031_1 peptidase - - - 0.0000000000000000000006712 98.0
TH1_k127_989768_0 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000005597 229.0
TH1_k127_989768_1 urea carboxylase K01941 - 6.3.4.6 0.000000000000000000000000000000000000000000000000000000006685 203.0
TH1_k127_998494_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 5.272e-232 728.0
TH1_k127_998494_1 PFAM transposase, IS4 family protein K07481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 382.0
TH1_k127_998494_2 PFAM regulatory protein DeoR K02444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 374.0
TH1_k127_998494_3 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000000000001058 231.0
TH1_k127_998494_4 - - - - 0.000000000000000000000000000000000000000001289 163.0
TH1_k127_998494_5 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000004647 103.0
TH1_k127_998494_6 Kazal type serine protease inhibitors - - - 0.0000005964 60.0