Overview

ID MAG03878
Name TH1_bin.57
Sample SMP0100
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Casimicrobiaceae
Genus CAIWHR01
Species
Assembly information
Completeness (%) 100.0
Contamination (%) 3.35
GC content (%) 67.0
N50 (bp) 12,411
Genome size (bp) 3,265,676

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3186

Gene name Description KEGG GOs EC E-value Score Sequence
TH1_k127_10696_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 1.008e-195 619.0
TH1_k127_10696_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 491.0
TH1_k127_10696_2 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000004516 119.0
TH1_k127_108044_0 Pyridine nucleotide-disulphide oxidoreductase - - - 6.071e-319 987.0
TH1_k127_108044_1 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 3.354e-297 923.0
TH1_k127_108044_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 505.0
TH1_k127_108044_3 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 340.0
TH1_k127_108044_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 315.0
TH1_k127_108044_5 electron transfer activity K03737,K05337 - 1.2.7.1 0.000001671 61.0
TH1_k127_1135219_0 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 7.749e-225 715.0
TH1_k127_1135219_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 414.0
TH1_k127_1135219_2 ABC transport system ATP-binding protein K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 389.0
TH1_k127_1135219_3 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 378.0
TH1_k127_1135219_4 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 365.0
TH1_k127_1135219_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000257 221.0
TH1_k127_1135219_6 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.000000000000000000000000000000000000000009503 169.0
TH1_k127_1135219_7 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000001798 156.0
TH1_k127_1135219_8 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000000002155 144.0
TH1_k127_1172_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 575.0
TH1_k127_1172_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 492.0
TH1_k127_1172_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 449.0
TH1_k127_1172_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 415.0
TH1_k127_1172_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 301.0
TH1_k127_1172_5 GrpE K03687 - - 0.00000000000000000000000000000000000000000000000000519 187.0
TH1_k127_1228468_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004803 242.0
TH1_k127_1228468_1 glycosyl transferase family 2 K20444 - - 0.000000000000000000000000000000002284 133.0
TH1_k127_1228468_3 nuclease activity K07062 - - 0.0000000000889 67.0
TH1_k127_1231022_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1062.0
TH1_k127_1231022_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.349e-227 715.0
TH1_k127_1231022_10 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000003195 234.0
TH1_k127_1231022_11 COG3245 Cytochrome c5 - - - 0.0000000000000000000000000000000000000000000000000000000000005209 225.0
TH1_k127_1231022_12 - - - - 0.0000000000000000000000000005757 125.0
TH1_k127_1231022_13 Colicin V production K03558 - - 0.00000000000000000000000001012 117.0
TH1_k127_1231022_14 Sporulation related domain K03749 - - 0.0000000000000000009583 96.0
TH1_k127_1231022_15 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000001585 80.0
TH1_k127_1231022_16 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000003142 79.0
TH1_k127_1231022_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.547e-222 695.0
TH1_k127_1231022_3 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.724e-203 640.0
TH1_k127_1231022_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.577e-195 621.0
TH1_k127_1231022_5 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 557.0
TH1_k127_1231022_6 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 455.0
TH1_k127_1231022_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 443.0
TH1_k127_1231022_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 349.0
TH1_k127_1231022_9 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000005666 237.0
TH1_k127_125189_0 Large family of predicted nucleotide-binding domains K07175 - - 2.911e-242 756.0
TH1_k127_125189_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 369.0
TH1_k127_125189_2 Redoxin K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000001968 224.0
TH1_k127_125189_3 cyclic-guanylate-specific phosphodiesterase activity - - - 0.00007383 51.0
TH1_k127_1255022_0 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002021 267.0
TH1_k127_1255022_1 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000008045 157.0
TH1_k127_1261622_0 belongs to the aldehyde dehydrogenase family K22187 - - 1.289e-229 720.0
TH1_k127_1261622_1 fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 546.0
TH1_k127_1261622_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 422.0
TH1_k127_1261622_3 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000001436 198.0
TH1_k127_1264123_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007696 284.0
TH1_k127_1264123_1 phenylacetic acid degradation operon negative regulatory protein K02616 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006082,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006805,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010124,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010817,GO:0016054,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043170,GO:0043254,GO:0043436,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0098754,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009651 274.0
TH1_k127_1264123_2 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005812 248.0
TH1_k127_1264123_3 Phenylacetic acid catabolic protein K02609 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.14.13.149 0.0000000000005034 71.0
TH1_k127_1271157_0 Protein of unknown function (DUF3141) - - - 0.0 1065.0
TH1_k127_1271157_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 548.0
TH1_k127_1271157_2 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 460.0
TH1_k127_1271157_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.00000000000000000000000000000000000000000004052 167.0
TH1_k127_1271157_4 - - - - 0.000000000003966 71.0
TH1_k127_1279660_0 molybdopterin cofactor binding K08352 - 1.8.5.5 1.197e-295 919.0
TH1_k127_1279660_1 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 407.0
TH1_k127_1279660_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 340.0
TH1_k127_1279660_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 319.0
TH1_k127_1279660_4 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 302.0
TH1_k127_1279660_5 ABC transporter K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 310.0
TH1_k127_1279660_6 sodium ABC transporter, permease K09696 - - 0.0000000000000000000000000000000000000000007695 167.0
TH1_k127_1279660_7 PIN domain - - - 0.000000000000000000000000000000000002339 141.0
TH1_k127_1282750_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2101.0
TH1_k127_1282750_1 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 2.883e-236 738.0
TH1_k127_1282750_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.981e-194 627.0
TH1_k127_1282750_3 TIGRFAM arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 576.0
TH1_k127_1282750_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 482.0
TH1_k127_1282750_5 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 317.0
TH1_k127_1292562_0 CbbX protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 451.0
TH1_k127_1292562_1 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000001627 237.0
TH1_k127_1292562_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000002484 232.0
TH1_k127_1292562_3 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000005065 181.0
TH1_k127_1300371_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.727e-214 681.0
TH1_k127_1300371_1 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 534.0
TH1_k127_1300371_10 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000003648 182.0
TH1_k127_1300371_11 Stringent starvation protein B K03600 - - 0.00000000000000000000000000000000004225 139.0
TH1_k127_1300371_2 Belongs to the peptidase S1C family K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 428.0
TH1_k127_1300371_3 nadph quinone oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 421.0
TH1_k127_1300371_4 KR domain K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 356.0
TH1_k127_1300371_5 Glutathione S-transferase K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 340.0
TH1_k127_1300371_6 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 307.0
TH1_k127_1300371_7 Cytochrome C1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 288.0
TH1_k127_1300371_8 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001843 268.0
TH1_k127_1300371_9 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000001879 226.0
TH1_k127_1302370_0 major pilin protein fima - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 350.0
TH1_k127_1302370_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 297.0
TH1_k127_1302370_2 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000001611 121.0
TH1_k127_1306789_0 PFAM Orn Lys Arg decarboxylase major region K01582,K01584 - 4.1.1.18,4.1.1.19 8.4e-323 1004.0
TH1_k127_1306789_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K13252 - 2.1.3.3,2.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 559.0
TH1_k127_1306789_2 Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 482.0
TH1_k127_1306789_3 Orn/Lys/Arg decarboxylase, N-terminal domain K01581 - 4.1.1.17 0.000000000000000000000000002347 115.0
TH1_k127_131108_0 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 548.0
TH1_k127_131108_1 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 312.0
TH1_k127_131108_2 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001881 255.0
TH1_k127_131108_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000001156 124.0
TH1_k127_1322518_0 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 573.0
TH1_k127_1322518_1 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 389.0
TH1_k127_1322518_2 polysaccharide deacetylase - - - 0.00000000000000000000000000002564 123.0
TH1_k127_1322518_3 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000001078 74.0
TH1_k127_1327481_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1420.0
TH1_k127_1327481_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 441.0
TH1_k127_1327481_2 Protein of unknown function (DUF1631) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 401.0
TH1_k127_1327481_3 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000191 292.0
TH1_k127_1327481_4 MaoC like domain - - - 0.000000000000000000000000000000000000000000000003682 177.0
TH1_k127_1327481_5 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000000000000000000001179 167.0
TH1_k127_1327481_6 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000003459 68.0
TH1_k127_1327614_0 ABC-2 family transporter protein - - - 0.0 1086.0
TH1_k127_1327614_1 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 401.0
TH1_k127_1327614_2 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000008807 251.0
TH1_k127_1327614_3 ribonuclease activity - - - 0.000000000000000000000000000000000004152 145.0
TH1_k127_1327614_4 AMP-binding enzyme C-terminal domain K18661 - - 0.000000000000000000000005012 106.0
TH1_k127_1327614_5 positive regulation of growth - - - 0.000000000000008124 76.0
TH1_k127_134382_0 Histidine kinase-like ATPases - - - 5.222e-277 882.0
TH1_k127_134382_1 Bacterial transcriptional activator domain - - - 0.000000000009605 76.0
TH1_k127_1364634_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 304.0
TH1_k127_1364634_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000002404 136.0
TH1_k127_1386577_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.331e-290 908.0
TH1_k127_1386577_1 Proton-conducting membrane transporter - - - 4.952e-278 869.0
TH1_k127_1386577_2 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 8.205e-237 739.0
TH1_k127_1386577_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 448.0
TH1_k127_1386577_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 441.0
TH1_k127_1386577_5 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 314.0
TH1_k127_1386577_6 PFAM NADH dehydrogenase (ubiquinone) 30 kDa subunit - - - 0.0000000000000000000000000000000000000000000000002004 182.0
TH1_k127_1393333_0 D-galactarate dehydratase Altronate hydrolase, C terminus K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 3.059e-213 668.0
TH1_k127_1393333_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.285e-200 641.0
TH1_k127_1393333_10 SAF K16845 - 4.4.1.24 0.0000000000000000000000000000000000004834 142.0
TH1_k127_1393333_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 385.0
TH1_k127_1393333_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 363.0
TH1_k127_1393333_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 314.0
TH1_k127_1393333_5 4Fe-4S dicluster domain K05796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 306.0
TH1_k127_1393333_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000002394 230.0
TH1_k127_1393333_7 dioxygenase of extradiol dioxygenase family K06991 - - 0.0000000000000000000000000000000000000000000000000000001183 204.0
TH1_k127_1393333_8 inositol monophosphatase K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0031403,GO:0031420,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0047954,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.0000000000000000000000000000000000000000000000000000004751 205.0
TH1_k127_1393333_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000002216 179.0
TH1_k127_139365_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K22015 - 1.17.1.9,1.17.99.7 0.0 1222.0
TH1_k127_139365_1 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 342.0
TH1_k127_1405814_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.371e-236 744.0
TH1_k127_1405814_1 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 1.593e-220 699.0
TH1_k127_1405814_2 Phosphotransferase system, mannose fructose-specific component IIA K02821 - 2.7.1.194 0.0000000000000000000000000000000000000000000004115 170.0
TH1_k127_1405814_3 PFAM binding-protein-dependent transport systems inner membrane component K13895 - - 0.00000000000000000000000000000000000005435 143.0
TH1_k127_1405814_4 Phosphotransferase System K11189 - - 0.0000000000000000000000000000000006907 135.0
TH1_k127_1430806_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 515.0
TH1_k127_1430806_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 460.0
TH1_k127_1430806_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 333.0
TH1_k127_1430806_3 - - - - 0.000000000000000000000000000000000000000000005614 173.0
TH1_k127_1433014_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 470.0
TH1_k127_1433014_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 309.0
TH1_k127_1433014_2 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000005114 124.0
TH1_k127_145312_0 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 512.0
TH1_k127_145312_1 deiminase K05603 - 3.5.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008186 490.0
TH1_k127_145312_2 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 486.0
TH1_k127_145312_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 440.0
TH1_k127_145312_4 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 327.0
TH1_k127_145312_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 285.0
TH1_k127_1459266_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1212.0
TH1_k127_1459266_1 DNA topoisomerase III K03169 - 5.99.1.2 0.0 1148.0
TH1_k127_1459266_10 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 478.0
TH1_k127_1459266_11 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 442.0
TH1_k127_1459266_12 Tripartite tricarboxylate transporter TctA K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 410.0
TH1_k127_1459266_13 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 410.0
TH1_k127_1459266_14 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 407.0
TH1_k127_1459266_15 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 397.0
TH1_k127_1459266_16 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 395.0
TH1_k127_1459266_17 RNA polymerase sigma K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 363.0
TH1_k127_1459266_18 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 375.0
TH1_k127_1459266_19 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 355.0
TH1_k127_1459266_2 Transport of potassium into the cell K03549 - - 1.247e-240 758.0
TH1_k127_1459266_20 PFAM conserved K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 338.0
TH1_k127_1459266_21 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 328.0
TH1_k127_1459266_22 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 301.0
TH1_k127_1459266_23 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 311.0
TH1_k127_1459266_24 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 294.0
TH1_k127_1459266_25 Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001885 277.0
TH1_k127_1459266_26 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002446 276.0
TH1_k127_1459266_27 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004776 245.0
TH1_k127_1459266_28 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000007445 237.0
TH1_k127_1459266_29 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000001368 232.0
TH1_k127_1459266_3 Dynamin family - - - 1.168e-219 701.0
TH1_k127_1459266_30 PFAM DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000002926 228.0
TH1_k127_1459266_31 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000004221 227.0
TH1_k127_1459266_32 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000001567 216.0
TH1_k127_1459266_33 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000008011 178.0
TH1_k127_1459266_34 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000002411 172.0
TH1_k127_1459266_35 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000005799 153.0
TH1_k127_1459266_36 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000003757 121.0
TH1_k127_1459266_37 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000003838 101.0
TH1_k127_1459266_38 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000179 76.0
TH1_k127_1459266_39 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000001815 60.0
TH1_k127_1459266_4 Histidine kinase - - - 4.81e-200 652.0
TH1_k127_1459266_40 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000002257 59.0
TH1_k127_1459266_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 580.0
TH1_k127_1459266_6 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 571.0
TH1_k127_1459266_7 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 539.0
TH1_k127_1459266_8 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 515.0
TH1_k127_1459266_9 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 506.0
TH1_k127_1462754_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000003051 230.0
TH1_k127_1462754_1 TIR domain - - - 0.0000000000005737 81.0
TH1_k127_1482461_0 transport system, fused permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 616.0
TH1_k127_1482461_1 fad dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 471.0
TH1_k127_1482461_2 transport system periplasmic component K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 468.0
TH1_k127_1482461_3 Domain of unknown function (DUF1850) - - - 0.000000002754 70.0
TH1_k127_1506781_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.71e-200 630.0
TH1_k127_1506781_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 601.0
TH1_k127_1506781_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002781 272.0
TH1_k127_1506781_3 UPF0056 inner membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000001445 223.0
TH1_k127_1506781_4 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000004232 202.0
TH1_k127_1506781_5 Cytochrome C' - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000002014 132.0
TH1_k127_1506781_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000001354 68.0
TH1_k127_1509650_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1089.0
TH1_k127_1509650_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 559.0
TH1_k127_1509650_10 - - - - 0.000000000001011 74.0
TH1_k127_1509650_2 ErfK YbiS YcfS YnhG family protein K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 426.0
TH1_k127_1509650_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000009948 224.0
TH1_k127_1509650_4 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000004292 188.0
TH1_k127_1509650_5 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000489 181.0
TH1_k127_1509650_6 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000001105 173.0
TH1_k127_1509650_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000005093 166.0
TH1_k127_1509650_8 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000002389 143.0
TH1_k127_1509650_9 Modulates RecA activity K03565 - - 0.0000000000000000009546 99.0
TH1_k127_1511923_0 COG2010 Cytochrome c, mono- and diheme variants K15864 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1,1.7.99.1 1.822e-299 935.0
TH1_k127_1511923_1 Tripartite tricarboxylate transporter TctA family K07793 - - 5.061e-271 840.0
TH1_k127_1511923_10 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000000000004655 188.0
TH1_k127_1511923_11 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000000000003392 114.0
TH1_k127_1511923_12 Cytochrome D1 heme domain - - - 0.0000000000000000003369 95.0
TH1_k127_1511923_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 528.0
TH1_k127_1511923_3 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 444.0
TH1_k127_1511923_4 Protein of unknown function (DUF808) K09781 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 374.0
TH1_k127_1511923_5 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 340.0
TH1_k127_1511923_6 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 296.0
TH1_k127_1511923_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 293.0
TH1_k127_1511923_8 cytochrome c-type protein K02569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 291.0
TH1_k127_1511923_9 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001733 271.0
TH1_k127_1533843_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 3.622e-200 640.0
TH1_k127_1533843_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 5.868e-200 642.0
TH1_k127_1533843_10 peptidase, S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 355.0
TH1_k127_1533843_11 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 339.0
TH1_k127_1533843_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 310.0
TH1_k127_1533843_13 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007172 260.0
TH1_k127_1533843_14 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005167 252.0
TH1_k127_1533843_15 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000006667 255.0
TH1_k127_1533843_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000001869 237.0
TH1_k127_1533843_17 HAD-superfamily hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000001971 231.0
TH1_k127_1533843_18 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000000000000005981 225.0
TH1_k127_1533843_19 Nitrogen regulatory protein P-II K04751 - - 0.0000000000000000000000000000000000000000000000000000000001297 205.0
TH1_k127_1533843_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 623.0
TH1_k127_1533843_20 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000006734 146.0
TH1_k127_1533843_21 rieske 2fe-2s - - - 0.000000000000000000000000000008712 131.0
TH1_k127_1533843_3 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 493.0
TH1_k127_1533843_4 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 496.0
TH1_k127_1533843_5 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 426.0
TH1_k127_1533843_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 415.0
TH1_k127_1533843_7 drug resistance transporter K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 396.0
TH1_k127_1533843_8 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 378.0
TH1_k127_1533843_9 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 364.0
TH1_k127_1571443_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002619 286.0
TH1_k127_1588209_0 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 610.0
TH1_k127_1588209_1 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 294.0
TH1_k127_1591780_0 ribonuclease, Rne Rng family K08301 - - 4.549e-223 699.0
TH1_k127_1591780_1 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001484 210.0
TH1_k127_1591780_2 PFAM alanine racemase domain protein K19967 - 4.1.2.42 0.000000000000000000000000000000000000000000000000000000003427 203.0
TH1_k127_1591780_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000001743 151.0
TH1_k127_1601384_0 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 1.198e-210 662.0
TH1_k127_1601384_1 polyphosphate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 586.0
TH1_k127_1601384_2 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 383.0
TH1_k127_1601384_3 CHAD - - - 0.0000000000000000000000000000000000000000000000000000000009358 217.0
TH1_k127_1624202_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 3.039e-217 689.0
TH1_k127_1624202_1 reverse transcriptase - - - 0.00000000002863 68.0
TH1_k127_1627695_0 Thiamine pyrophosphate enzyme, central domain K04103 - 4.1.1.74 2.958e-251 785.0
TH1_k127_1627695_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 5.376e-249 781.0
TH1_k127_1627695_10 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 327.0
TH1_k127_1627695_11 Protein of unknown function, DUF480 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 285.0
TH1_k127_1627695_12 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003009 293.0
TH1_k127_1627695_13 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000006047 257.0
TH1_k127_1627695_14 PFAM AMMECR1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007184 229.0
TH1_k127_1627695_15 hydrogenase maturation protease - - - 0.0000000000000000000000000000000000003707 149.0
TH1_k127_1627695_16 MazG-like family - - - 0.000000000000000000000000000000003357 132.0
TH1_k127_1627695_2 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 6.753e-228 717.0
TH1_k127_1627695_3 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 4.744e-202 634.0
TH1_k127_1627695_4 Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 586.0
TH1_k127_1627695_5 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 414.0
TH1_k127_1627695_6 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 377.0
TH1_k127_1627695_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 372.0
TH1_k127_1627695_8 mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 333.0
TH1_k127_1627695_9 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 340.0
TH1_k127_1652351_0 LysM domain K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 362.0
TH1_k127_1652351_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 309.0
TH1_k127_1652351_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000007324 207.0
TH1_k127_1677166_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1261.0
TH1_k127_1677166_1 PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A K01908 - 6.2.1.17 2.656e-316 977.0
TH1_k127_1677166_10 Pyridoxal phosphate biosynthesis protein PdxJ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 398.0
TH1_k127_1677166_11 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 390.0
TH1_k127_1677166_12 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 374.0
TH1_k127_1677166_13 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 344.0
TH1_k127_1677166_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 322.0
TH1_k127_1677166_15 Peptidase S24-like K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 330.0
TH1_k127_1677166_16 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004512 254.0
TH1_k127_1677166_17 Sigma E regulatory protein, MucB RseB K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000004137 246.0
TH1_k127_1677166_18 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000008512 237.0
TH1_k127_1677166_19 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000006524 246.0
TH1_k127_1677166_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.702e-314 970.0
TH1_k127_1677166_20 PFAM glutaredoxin 2 - - - 0.0000000000000000007456 90.0
TH1_k127_1677166_21 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.000000000000000006005 96.0
TH1_k127_1677166_22 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000005383 89.0
TH1_k127_1677166_23 Domain of unknown function (DUF4845) - - - 0.00000000000007476 83.0
TH1_k127_1677166_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.435e-243 757.0
TH1_k127_1677166_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.556e-221 701.0
TH1_k127_1677166_5 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 554.0
TH1_k127_1677166_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 544.0
TH1_k127_1677166_7 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 514.0
TH1_k127_1677166_8 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 446.0
TH1_k127_1677166_9 PFAM AFG1-family ATPase K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 439.0
TH1_k127_1679096_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 520.0
TH1_k127_1679096_1 Carbon-nitrogen hydrolase K01501,K01502 GO:0000257,GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016787,GO:0016810,GO:0016815,GO:0018762,GO:0022607,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0065003,GO:0071840 3.5.5.1,3.5.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 435.0
TH1_k127_1679096_2 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 303.0
TH1_k127_1679096_3 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003634 267.0
TH1_k127_1679096_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000000001671 168.0
TH1_k127_1679096_5 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000000825 158.0
TH1_k127_1679096_6 Cmp dcmp deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000003245 143.0
TH1_k127_1706640_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.855e-313 967.0
TH1_k127_1706640_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.682e-202 666.0
TH1_k127_1706640_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000007639 192.0
TH1_k127_1722929_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 479.0
TH1_k127_1722929_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 462.0
TH1_k127_1722929_2 Permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 373.0
TH1_k127_1722929_3 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 300.0
TH1_k127_1722929_4 cheY-homologous receiver domain K11443 - - 0.00000000000000000000000000000000000000000004657 174.0
TH1_k127_1722929_5 nitric oxide dioxygenase activity - - - 0.0000000000000000000000000000000000000000001563 163.0
TH1_k127_1722929_6 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000003095 111.0
TH1_k127_1722929_7 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.000000001451 66.0
TH1_k127_1723056_0 RNB K01147 - 3.1.13.1 1.845e-200 642.0
TH1_k127_1723056_1 Acts as a magnesium transporter K06213 - - 3.274e-198 629.0
TH1_k127_1723056_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000003578 192.0
TH1_k127_1723056_11 Secreted repeat of unknown function - - - 0.0000000000000000000000000000000000000000000000005958 181.0
TH1_k127_1723056_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000003753 159.0
TH1_k127_1723056_13 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.0000000001581 64.0
TH1_k127_1723056_2 AAA domain K07133 - - 1.143e-194 613.0
TH1_k127_1723056_3 TIGRFAM TRAP transporter, DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 580.0
TH1_k127_1723056_4 PFAM oxidoreductase domain protein K19181 - 1.1.1.292 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 533.0
TH1_k127_1723056_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 450.0
TH1_k127_1723056_6 Shikimate dehydrogenase substrate binding domain protein K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 406.0
TH1_k127_1723056_7 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 301.0
TH1_k127_1723056_8 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001158 287.0
TH1_k127_1723056_9 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000287 275.0
TH1_k127_1725308_0 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 484.0
TH1_k127_1725308_1 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 452.0
TH1_k127_1725308_2 KR domain K07535 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 298.0
TH1_k127_1725308_3 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000736 275.0
TH1_k127_1725308_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009271 267.0
TH1_k127_1725308_5 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000345 232.0
TH1_k127_1725308_6 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000895 115.0
TH1_k127_1725308_7 AMP-binding enzyme K01895 - 6.2.1.1 0.00000000000000000000006264 104.0
TH1_k127_1725308_8 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000008544 85.0
TH1_k127_1740173_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 454.0
TH1_k127_1740173_1 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 396.0
TH1_k127_1740173_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 390.0
TH1_k127_1740173_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000001347 275.0
TH1_k127_1740173_4 glycosyl transferase K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002816 250.0
TH1_k127_1740173_5 epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000002893 226.0
TH1_k127_1740173_6 Acetyltransferases including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000202 130.0
TH1_k127_1770438_0 tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 2.456e-198 629.0
TH1_k127_1770438_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 465.0
TH1_k127_1770438_2 Pfam Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 412.0
TH1_k127_1770438_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 410.0
TH1_k127_1770438_4 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 344.0
TH1_k127_1770438_5 FR47-like protein - - - 0.00000000000000000000000000000000000000008049 156.0
TH1_k127_1770438_6 Small Multidrug Resistance protein - - - 0.0000000000000000000000000000000004624 134.0
TH1_k127_1809630_0 glycolate oxidase subunit GlcD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 563.0
TH1_k127_1809630_1 Sigma-54 interaction domain protein K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 537.0
TH1_k127_1809630_2 M61 glycyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 482.0
TH1_k127_1809630_3 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 358.0
TH1_k127_1809630_4 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 310.0
TH1_k127_1809630_5 - - - - 0.00000000003476 69.0
TH1_k127_1809630_6 - K06950 - - 0.0000001454 55.0
TH1_k127_1811169_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1350.0
TH1_k127_1811169_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 406.0
TH1_k127_1811169_2 (Lipo)protein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 334.0
TH1_k127_1811169_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 327.0
TH1_k127_1811169_4 Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 312.0
TH1_k127_1811169_5 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000002746 201.0
TH1_k127_1811169_6 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000001119 97.0
TH1_k127_1811169_7 Protein of unknown function (DUF2970) - - - 0.00000001096 61.0
TH1_k127_1811169_8 - - - - 0.0000001812 54.0
TH1_k127_1822509_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 5.537e-244 764.0
TH1_k127_1822509_1 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 527.0
TH1_k127_1835542_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 415.0
TH1_k127_1835542_1 Mannitol dehydrogenase Rossmann domain K00040 - 1.1.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 372.0
TH1_k127_1835542_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000004379 87.0
TH1_k127_188517_0 PFAM polysaccharide biosynthesis protein CapD - - - 5.095e-220 704.0
TH1_k127_188517_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 5.624e-217 685.0
TH1_k127_188517_10 PFAM glycosyl transferase family 4 K13007 - - 0.0000000000000000000000000000000000000000000000000000000000000206 228.0
TH1_k127_188517_11 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000001741 204.0
TH1_k127_188517_12 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000002615 188.0
TH1_k127_188517_13 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000124 190.0
TH1_k127_188517_14 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000005356 171.0
TH1_k127_188517_15 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000007728 149.0
TH1_k127_188517_16 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000001326 144.0
TH1_k127_188517_17 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000137 133.0
TH1_k127_188517_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 542.0
TH1_k127_188517_3 Biotin and Thiamin Synthesis associated domain K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 479.0
TH1_k127_188517_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 437.0
TH1_k127_188517_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 403.0
TH1_k127_188517_6 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 351.0
TH1_k127_188517_7 Psort location Cytoplasmic, score 8.96 K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 313.0
TH1_k127_188517_8 PFAM regulatory protein TetR K05501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001127 250.0
TH1_k127_188517_9 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006834 248.0
TH1_k127_1899225_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 5.616e-258 812.0
TH1_k127_1899225_1 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 524.0
TH1_k127_1899225_2 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 451.0
TH1_k127_1899225_3 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 426.0
TH1_k127_1899225_4 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009337 287.0
TH1_k127_1899225_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000002466 269.0
TH1_k127_1899225_6 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002398 262.0
TH1_k127_1899225_7 Isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000000000187 197.0
TH1_k127_191125_0 FAD dependent oxidoreductase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 537.0
TH1_k127_191125_1 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001233 242.0
TH1_k127_2129405_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 6.123e-296 932.0
TH1_k127_2129405_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.17e-204 645.0
TH1_k127_2129405_10 Transcriptional regulator - - - 0.0000000000000000192 89.0
TH1_k127_2129405_11 radical SAM domain protein - - - 0.000000000562 63.0
TH1_k127_2129405_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 552.0
TH1_k127_2129405_3 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 353.0
TH1_k127_2129405_4 2-keto-4-pentenoate hydratase K01617 - 4.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000008649 244.0
TH1_k127_2129405_5 Tetratricopeptide repeat K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000002286 239.0
TH1_k127_2129405_6 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.00000000000000000000000000000000000000000000000000000000001248 215.0
TH1_k127_2129405_7 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000007458 210.0
TH1_k127_2129405_8 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000007716 189.0
TH1_k127_2129405_9 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000145 121.0
TH1_k127_2167970_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 598.0
TH1_k127_2167970_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 456.0
TH1_k127_2167970_2 RNA polymerase sigma factor K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 357.0
TH1_k127_2167970_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 353.0
TH1_k127_2167970_4 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 344.0
TH1_k127_2167970_5 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005691 286.0
TH1_k127_2167970_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001412 252.0
TH1_k127_2204092_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 2.021e-294 913.0
TH1_k127_2204092_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 2.002e-278 861.0
TH1_k127_2204092_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 391.0
TH1_k127_2204092_3 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 295.0
TH1_k127_2204092_4 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000007498 191.0
TH1_k127_2204092_5 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000203 198.0
TH1_k127_2204092_6 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000008213 189.0
TH1_k127_2204092_7 glyoxalase III activity K00799 - 2.5.1.18 0.0000000000000000000000000000007021 129.0
TH1_k127_2204092_8 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000002983 93.0
TH1_k127_2204092_9 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000009297 68.0
TH1_k127_2301896_0 COG0457 FOG TPR repeat - - - 2.368e-221 694.0
TH1_k127_2301896_1 domain, Protein - - - 0.0000000000000000000000000000001195 126.0
TH1_k127_2301896_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000481 102.0
TH1_k127_2336667_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1554.0
TH1_k127_2336667_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 447.0
TH1_k127_2336667_10 guanyl-nucleotide exchange factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001697 277.0
TH1_k127_2336667_11 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001822 262.0
TH1_k127_2336667_12 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006318 255.0
TH1_k127_2336667_13 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002848 242.0
TH1_k127_2336667_14 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.000000000000000000000000000000000000000000000000000000000000000000379 240.0
TH1_k127_2336667_15 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000006474 235.0
TH1_k127_2336667_16 molybdopterin-guanine dinucleotide biosynthesis protein b K03753 - - 0.0000000000000000000000000000000000000000000000000000000000008576 214.0
TH1_k127_2336667_17 OHCU decarboxylase K13485 - 4.1.1.97 0.0000000000000000000000000000000000000000000000000000001863 199.0
TH1_k127_2336667_18 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.000000000000000000000000000000000000000000008989 171.0
TH1_k127_2336667_19 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000002685 166.0
TH1_k127_2336667_2 Bacterial periplasmic substrate-binding proteins K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 447.0
TH1_k127_2336667_20 - - - - 0.0000000000000000000000000000000000000000001045 166.0
TH1_k127_2336667_21 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000005047 103.0
TH1_k127_2336667_22 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000001384 87.0
TH1_k127_2336667_23 - - - - 0.0000000000000000425 83.0
TH1_k127_2336667_24 Dehydrogenase - - - 0.0000001041 59.0
TH1_k127_2336667_25 ABC transporter K02028,K02029,K10004 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21 0.000002465 49.0
TH1_k127_2336667_26 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.000003829 57.0
TH1_k127_2336667_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 456.0
TH1_k127_2336667_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 430.0
TH1_k127_2336667_5 PFAM PfkB domain protein K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 352.0
TH1_k127_2336667_6 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 333.0
TH1_k127_2336667_7 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 315.0
TH1_k127_2336667_8 Binding-protein-dependent transport system inner membrane component K10002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 309.0
TH1_k127_2336667_9 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004021 284.0
TH1_k127_2437338_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1429.0
TH1_k127_2437338_1 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1068.0
TH1_k127_2437338_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 307.0
TH1_k127_2437338_11 Beta/Gamma crystallin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001491 280.0
TH1_k127_2437338_12 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000003805 271.0
TH1_k127_2437338_13 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000004186 225.0
TH1_k127_2437338_14 Psort location CytoplasmicMembrane, score K09793 - - 0.00000000000000000000000000000000000001065 167.0
TH1_k127_2437338_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000271 124.0
TH1_k127_2437338_16 Protein of unknown function (DUF2442) - - - 0.000000000000000001585 92.0
TH1_k127_2437338_2 RNA secondary structure unwinding K03724 - - 1.455e-297 934.0
TH1_k127_2437338_3 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 1.641e-204 642.0
TH1_k127_2437338_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 546.0
TH1_k127_2437338_5 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 497.0
TH1_k127_2437338_6 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 462.0
TH1_k127_2437338_7 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 455.0
TH1_k127_2437338_8 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 366.0
TH1_k127_2437338_9 Belongs to the peptidase S1C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 350.0
TH1_k127_244034_0 STAS domain K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 620.0
TH1_k127_244034_1 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 566.0
TH1_k127_244034_10 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000009605 246.0
TH1_k127_244034_11 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000001453 224.0
TH1_k127_244034_12 Ferredoxin - - - 0.000000000000000000000000000000000000000000009289 164.0
TH1_k127_244034_13 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000000003042 153.0
TH1_k127_244034_14 O-Antigen ligase - - - 0.000000000000000000000000001143 123.0
TH1_k127_244034_15 FabA-like domain - - - 0.000000000000000000000004831 117.0
TH1_k127_244034_16 THUMP K07444 - - 0.0000003741 62.0
TH1_k127_244034_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 556.0
TH1_k127_244034_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 454.0
TH1_k127_244034_4 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 434.0
TH1_k127_244034_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 426.0
TH1_k127_244034_6 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 370.0
TH1_k127_244034_7 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009376 337.0
TH1_k127_244034_8 KR domain K10780 - 1.3.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 300.0
TH1_k127_244034_9 lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000003871 261.0
TH1_k127_2441714_0 similarity to GP 3192745 - - - 7.671e-207 651.0
TH1_k127_2441714_1 transcriptional regulator - - - 0.0000000000000000000000008892 109.0
TH1_k127_2446180_0 Helicase K03657 - 3.6.4.12 4.038e-289 903.0
TH1_k127_2446180_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 383.0
TH1_k127_2446180_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 342.0
TH1_k127_2446180_3 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 328.0
TH1_k127_2446180_4 Protein of unknown function (DUF2782) - - - 0.00000000000000000000003937 103.0
TH1_k127_2446180_5 - - - - 0.000000000002169 78.0
TH1_k127_2452540_0 Protein of unknown function (DUF1329) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 612.0
TH1_k127_2452540_1 Protein of unknown function (DUF1302) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 587.0
TH1_k127_2452540_2 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002767 258.0
TH1_k127_2452540_3 AcrB/AcrD/AcrF family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000001883 228.0
TH1_k127_2465238_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2275.0
TH1_k127_2465238_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 8.79e-297 914.0
TH1_k127_2465238_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 346.0
TH1_k127_2465238_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 314.0
TH1_k127_2465238_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006255 262.0
TH1_k127_2465238_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000001175 240.0
TH1_k127_2465238_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000009467 239.0
TH1_k127_2465238_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000002245 172.0
TH1_k127_2465238_8 SecE/Sec61-gamma subunits of protein translocation complex K03073 - - 0.000000000000000000000000000001373 124.0
TH1_k127_2465238_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000005461 53.0
TH1_k127_2471364_0 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 565.0
TH1_k127_2471364_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 517.0
TH1_k127_2471364_2 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 464.0
TH1_k127_2471364_3 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007967 273.0
TH1_k127_2471364_4 - - - - 0.000000000000000000000000000000000000000000000000007128 186.0
TH1_k127_2471364_5 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000002978 132.0
TH1_k127_2471364_6 cell redox homeostasis - - - 0.0000000000000000002001 89.0
TH1_k127_2471364_7 Cro/C1-type HTH DNA-binding domain - - - 0.000005226 55.0
TH1_k127_2480679_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1463.0
TH1_k127_2480679_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1414.0
TH1_k127_2480679_10 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004138 261.0
TH1_k127_2480679_11 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 0.0000000000000000000000000000000000371 137.0
TH1_k127_2480679_12 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000000000000000005302 132.0
TH1_k127_2480679_13 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000000000000000003707 132.0
TH1_k127_2480679_14 Helix-turn-helix domain - - - 0.00000000001525 69.0
TH1_k127_2480679_2 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 0.0 1389.0
TH1_k127_2480679_3 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 4.138e-308 961.0
TH1_k127_2480679_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 538.0
TH1_k127_2480679_5 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 493.0
TH1_k127_2480679_6 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 398.0
TH1_k127_2480679_7 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 384.0
TH1_k127_2480679_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 326.0
TH1_k127_2480679_9 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001972 273.0
TH1_k127_2496364_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 3.223e-220 717.0
TH1_k127_2496364_1 PFAM Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 546.0
TH1_k127_2496364_10 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000002889 186.0
TH1_k127_2496364_11 Psort location CytoplasmicMembrane, score K02237 - - 0.00000000000000000001446 97.0
TH1_k127_2496364_12 TPM domain K08988 - - 0.000001105 51.0
TH1_k127_2496364_2 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 491.0
TH1_k127_2496364_3 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 482.0
TH1_k127_2496364_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 403.0
TH1_k127_2496364_5 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 396.0
TH1_k127_2496364_6 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 359.0
TH1_k127_2496364_7 3'-5' exonuclease K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 353.0
TH1_k127_2496364_8 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 291.0
TH1_k127_2496364_9 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000001495 225.0
TH1_k127_2521107_0 Phospholipase, patatin family K07001 - - 4.432e-209 662.0
TH1_k127_2521107_1 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 3.203e-194 615.0
TH1_k127_2521107_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 542.0
TH1_k127_2521107_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 373.0
TH1_k127_2521107_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 368.0
TH1_k127_2521107_5 PFAM integrase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 314.0
TH1_k127_2521107_6 - - - - 0.000000000000000005012 92.0
TH1_k127_2521107_7 Domain of unknown function (DUF202) K00389 - - 0.000000000000000007542 89.0
TH1_k127_2521107_8 - - - - 0.000001416 52.0
TH1_k127_2537729_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 374.0
TH1_k127_2537729_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 348.0
TH1_k127_2537729_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00003487 47.0
TH1_k127_2550933_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1506.0
TH1_k127_2550933_1 Tripartite tricarboxylate transporter TctA family K07793 - - 3.165e-236 741.0
TH1_k127_2550933_10 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.00000000000000002331 81.0
TH1_k127_2550933_2 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 1.693e-209 670.0
TH1_k127_2550933_3 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 5.834e-195 645.0
TH1_k127_2550933_4 Phenylacetic acid degradation protein PaaY K02617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 297.0
TH1_k127_2550933_5 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000146 274.0
TH1_k127_2550933_6 PFAM N-acetylmuramoyl-L-alanine amidase K03806 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000001039 244.0
TH1_k127_2550933_7 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000007817 214.0
TH1_k127_2550933_8 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000006377 127.0
TH1_k127_2550933_9 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000007812 94.0
TH1_k127_2586386_0 PFAM sulfatase - - - 1.303e-205 667.0
TH1_k127_2586386_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 575.0
TH1_k127_2586386_2 synthetase K16029 - - 0.000000000000000000000000000000000000000000000002974 192.0
TH1_k127_2586386_3 chain release factor K15034 - - 0.000000000000000000000000000000000000000000008111 166.0
TH1_k127_2586386_4 Membrane protein involved in D-alanine export - - - 0.0000000000000000000000000000000000000003072 166.0
TH1_k127_2586386_5 - - - - 0.0000000000000000002962 91.0
TH1_k127_2586386_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0008329 48.0
TH1_k127_2588772_0 Poly-beta-hydroxybutyrate polymerase N terminal K03821 - - 5.109e-275 859.0
TH1_k127_2588772_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 9.403e-249 790.0
TH1_k127_2588772_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 455.0
TH1_k127_2588772_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000172 286.0
TH1_k127_2588772_4 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001104 246.0
TH1_k127_2588772_5 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000000000000001014 162.0
TH1_k127_2588772_6 - - - - 0.00000000000000000000000000000000001291 139.0
TH1_k127_2588772_7 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000000000007638 115.0
TH1_k127_2588772_8 - - - - 0.0000000000002203 77.0
TH1_k127_2596240_0 Orn/Lys/Arg decarboxylase, N-terminal domain - - - 0.0 1033.0
TH1_k127_2596240_1 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000002697 119.0
TH1_k127_2615861_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.032e-293 910.0
TH1_k127_2615861_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 6.221e-212 664.0
TH1_k127_2615861_2 NUDIX hydrolase K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000000000000002455 196.0
TH1_k127_2615861_3 guanine-specific ribonuclease N1 and T1 K01167 - 3.1.27.3 0.0000000000000000000000000000000000000001199 154.0
TH1_k127_2615861_4 Protein of unknown function (DUF502) - - - 0.000000000000000000001167 95.0
TH1_k127_2615861_5 Barstar (barnase inhibitor) - - - 0.000000000000000002357 91.0
TH1_k127_2615861_6 Protein of unknown function (DUF541) - - - 0.0000000000000004286 91.0
TH1_k127_2637377_0 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 565.0
TH1_k127_2637377_1 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006207 256.0
TH1_k127_2637377_2 Glycoprotease family K14742 - - 0.000000000000000000000000000000000000005116 157.0
TH1_k127_2637377_3 COG1651 Protein-disulfide isomerase K21990 - - 0.00000000000000000000000000000000001866 143.0
TH1_k127_2644956_0 amp-dependent synthetase and ligase K00666 - - 3.531e-280 903.0
TH1_k127_2644956_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.757e-275 858.0
TH1_k127_2644956_10 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000006036 125.0
TH1_k127_2644956_11 Phosphopantetheine attachment site - - - 0.000000000000000002123 91.0
TH1_k127_2644956_12 Protein of unknown function (DUF2934) - - - 0.0000002415 57.0
TH1_k127_2644956_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009858 470.0
TH1_k127_2644956_3 S-acyltransferase activity K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 462.0
TH1_k127_2644956_4 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 426.0
TH1_k127_2644956_5 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 438.0
TH1_k127_2644956_6 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 368.0
TH1_k127_2644956_7 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000001431 179.0
TH1_k127_2644956_8 dksA traR - - - 0.0000000000000000000000000000001113 129.0
TH1_k127_2644956_9 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000005242 126.0
TH1_k127_2648879_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 508.0
TH1_k127_2648879_1 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 430.0
TH1_k127_2648879_10 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000008364 181.0
TH1_k127_2648879_11 Glutathione-dependent formaldehyde-activating enzyme family protein 4 - - - 0.000000000000000000000000000000000005447 142.0
TH1_k127_2648879_12 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000000000000001386 140.0
TH1_k127_2648879_14 PFAM HNH endonuclease K07451 - - 0.0000000000000000000009198 102.0
TH1_k127_2648879_15 - - - - 0.000000000005696 70.0
TH1_k127_2648879_17 protein-(glutamine-N5) methyltransferase activity K21786 - - 0.0001734 48.0
TH1_k127_2648879_2 NUDIX domain K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 407.0
TH1_k127_2648879_3 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 335.0
TH1_k127_2648879_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 290.0
TH1_k127_2648879_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000269 285.0
TH1_k127_2648879_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009982 273.0
TH1_k127_2648879_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000001287 199.0
TH1_k127_2648879_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000005235 197.0
TH1_k127_2648879_9 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000000000000006256 178.0
TH1_k127_2660394_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 3.277e-206 655.0
TH1_k127_2660394_1 Glutaredoxin-family domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 420.0
TH1_k127_2660394_2 Transcriptional regulator, LysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 332.0
TH1_k127_2660394_3 - - - - 0.0000000000000000000000000000000000000000000000000000000009904 206.0
TH1_k127_2660394_4 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.0000000000000008445 79.0
TH1_k127_2665206_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.239e-307 968.0
TH1_k127_2665206_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 460.0
TH1_k127_2665206_2 LexA DNA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008409 258.0
TH1_k127_2665206_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000004794 224.0
TH1_k127_2665206_4 Glutathione S-transferase, N-terminal domain K11208 - - 0.000000000000000000000000000000000000000000000000000000000002209 212.0
TH1_k127_2667921_0 Male sterility protein K22025 - 1.1.1.410 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 374.0
TH1_k127_2667921_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 357.0
TH1_k127_2667921_2 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 315.0
TH1_k127_2667921_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000003046 241.0
TH1_k127_2667921_4 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000001465 209.0
TH1_k127_2667921_5 rRNA binding K00185,K02967 - - 0.00000000000000002528 89.0
TH1_k127_2718738_0 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 365.0
TH1_k127_2718738_1 Vitamin k epoxide reductase - - - 0.000000000000000000000009275 103.0
TH1_k127_2718738_2 Iron-sulfur cluster assembly protein - - - 0.0000000007974 59.0
TH1_k127_2727010_0 Bacterial extracellular solute-binding protein K02027 - - 5.419e-214 676.0
TH1_k127_2727010_1 ABC-type sugar K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 507.0
TH1_k127_2727010_2 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 526.0
TH1_k127_2727010_3 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 479.0
TH1_k127_2727010_4 TOBE domain K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 341.0
TH1_k127_2727010_5 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000001011 165.0
TH1_k127_2727010_6 of the major facilitator superfamily K08151 - - 0.0000006789 51.0
TH1_k127_2738675_0 Mechanosensitive ion channel K16052,K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 421.0
TH1_k127_2738675_1 terminase, large subunit K06909 - - 0.0002689 46.0
TH1_k127_2738811_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 5.572e-254 792.0
TH1_k127_2738811_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 9.919e-209 655.0
TH1_k127_2738811_10 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000005286 201.0
TH1_k127_2738811_11 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.000000000000000000000000000000000000000000002665 178.0
TH1_k127_2738811_12 GDP-mannose mannosyl hydrolase activity K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000000008661 160.0
TH1_k127_2738811_13 PFAM Sporulation domain protein - - - 0.000000000000000007127 92.0
TH1_k127_2738811_2 Methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 462.0
TH1_k127_2738811_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008193 375.0
TH1_k127_2738811_4 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 293.0
TH1_k127_2738811_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 292.0
TH1_k127_2738811_6 inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 299.0
TH1_k127_2738811_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000004232 259.0
TH1_k127_2738811_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000004144 233.0
TH1_k127_2738811_9 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.00000000000000000000000000000000000000000000000000000000002161 214.0
TH1_k127_2743884_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1317.0
TH1_k127_2743884_1 Belongs to the ClpA ClpB family K03694 - - 7.961e-248 772.0
TH1_k127_2743884_10 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 323.0
TH1_k127_2743884_11 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 310.0
TH1_k127_2743884_12 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005385 267.0
TH1_k127_2743884_13 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000008337 213.0
TH1_k127_2743884_14 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000008747 154.0
TH1_k127_2743884_15 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000004173 168.0
TH1_k127_2743884_16 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000001151 151.0
TH1_k127_2743884_17 Cold shock protein K03704 - - 0.000000000000000000000000000000000005098 136.0
TH1_k127_2743884_2 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 2.028e-242 764.0
TH1_k127_2743884_3 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 515.0
TH1_k127_2743884_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 505.0
TH1_k127_2743884_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 495.0
TH1_k127_2743884_6 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 380.0
TH1_k127_2743884_7 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 343.0
TH1_k127_2743884_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 327.0
TH1_k127_2743884_9 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 320.0
TH1_k127_2747063_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0 1202.0
TH1_k127_2747063_1 AAA domain K03582 - 3.1.11.5 0.0 1196.0
TH1_k127_2747063_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 1.735e-197 646.0
TH1_k127_2747063_3 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005317 263.0
TH1_k127_2747063_4 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.000000000000000000000001268 106.0
TH1_k127_2747063_5 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.000000000000000000523 94.0
TH1_k127_2768652_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1272.0
TH1_k127_2768652_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000482 199.0
TH1_k127_2768652_2 HTH-like domain K07497 - - 0.0000000000000000000000000003848 117.0
TH1_k127_2787566_0 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 325.0
TH1_k127_2787566_1 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.00000000000000000000000000000000000000000000000000000007649 202.0
TH1_k127_2820952_0 Desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 517.0
TH1_k127_2820952_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 503.0
TH1_k127_2820952_10 SpoVT / AbrB like domain - - - 0.00000000000000000000005169 101.0
TH1_k127_2820952_11 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000001932 96.0
TH1_k127_2820952_12 Protein of unknown function (DUF3108) - - - 0.0000000000000002455 91.0
TH1_k127_2820952_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 469.0
TH1_k127_2820952_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 459.0
TH1_k127_2820952_4 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 355.0
TH1_k127_2820952_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000006991 252.0
TH1_k127_2820952_6 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000004486 177.0
TH1_k127_2820952_7 Bacterial dnaA protein K10763 - - 0.000000000000000000000000000000000000000000000009975 181.0
TH1_k127_2820952_8 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000000000000000000000001651 155.0
TH1_k127_2820952_9 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000001571 141.0
TH1_k127_2835524_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 395.0
TH1_k127_2835524_1 transport system, fused permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 345.0
TH1_k127_2836715_0 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 368.0
TH1_k127_2837522_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 541.0
TH1_k127_2837522_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000000000000000000000000000000000006553 158.0
TH1_k127_284788_0 HELICc2 K03722 - 3.6.4.12 5.04e-238 762.0
TH1_k127_284788_1 Psort location Cytoplasmic, score 8.96 K07462 - - 4.902e-213 676.0
TH1_k127_284788_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 372.0
TH1_k127_284788_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 338.0
TH1_k127_284788_4 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 278.0
TH1_k127_284788_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002407 280.0
TH1_k127_284788_6 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000001498 242.0
TH1_k127_2855687_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 526.0
TH1_k127_2855687_1 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 487.0
TH1_k127_2855687_2 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 481.0
TH1_k127_2855687_3 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 445.0
TH1_k127_2855687_4 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 355.0
TH1_k127_2855687_5 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000009161 191.0
TH1_k127_2855687_6 Mut7-C ubiquitin - - - 0.000000000000000000000005091 117.0
TH1_k127_2855687_7 - - - - 0.000000000000007401 79.0
TH1_k127_2855687_8 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000001171 52.0
TH1_k127_2888031_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 1.954e-273 853.0
TH1_k127_2888031_1 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 7.346e-211 666.0
TH1_k127_2888031_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.048e-205 647.0
TH1_k127_2888031_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 566.0
TH1_k127_2888031_4 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 466.0
TH1_k127_2888031_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 310.0
TH1_k127_2888031_6 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000007859 243.0
TH1_k127_2888031_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000293 157.0
TH1_k127_2888031_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000009896 132.0
TH1_k127_2888031_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000001813 111.0
TH1_k127_290781_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.601e-239 745.0
TH1_k127_290781_1 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000005952 197.0
TH1_k127_290781_2 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000003256 177.0
TH1_k127_290781_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000675 149.0
TH1_k127_290781_4 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000004391 129.0
TH1_k127_290781_5 PFAM Cytochrome c, class I - - - 0.0000000000006961 72.0
TH1_k127_2913265_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.294e-231 734.0
TH1_k127_2913265_1 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 616.0
TH1_k127_2913265_2 e3 binding domain K09699 - 2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 481.0
TH1_k127_2913265_3 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit K00166 - 1.2.4.4 0.00000000000000000000000000009575 116.0
TH1_k127_2991211_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 574.0
TH1_k127_2991211_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 441.0
TH1_k127_3022074_0 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 597.0
TH1_k127_3022074_1 - - - - 0.0000004443 56.0
TH1_k127_3022074_2 Belongs to the UPF0307 family K09889 - - 0.00003816 53.0
TH1_k127_3084426_0 PFAM ABC transporter K02049,K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 427.0
TH1_k127_3084426_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 413.0
TH1_k127_3084426_2 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 377.0
TH1_k127_3133804_0 AcyL-CoA dehydrogenase K06445 - - 0.0 1084.0
TH1_k127_3133804_1 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - - 3.982e-299 930.0
TH1_k127_3133804_10 Bacterial transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000167 209.0
TH1_k127_3133804_11 - - - - 0.000000000000000000000000000000000000000000000000006677 190.0
TH1_k127_3133804_12 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000008889 178.0
TH1_k127_3133804_13 PFAM poly granule associated family protein - - - 0.000000000000000000000000022 114.0
TH1_k127_3133804_14 PFAM acyl-coA-binding protein, ACBP - - - 0.000000000000000000000002282 105.0
TH1_k127_3133804_15 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.000000002598 72.0
TH1_k127_3133804_16 - - - - 0.0005096 49.0
TH1_k127_3133804_2 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.468e-249 786.0
TH1_k127_3133804_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 2.602e-248 777.0
TH1_k127_3133804_4 Belongs to the thiolase family K00626 - 2.3.1.9 7.129e-222 694.0
TH1_k127_3133804_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 1.154e-215 674.0
TH1_k127_3133804_6 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 446.0
TH1_k127_3133804_7 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 408.0
TH1_k127_3133804_8 B12 binding domain K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 306.0
TH1_k127_3133804_9 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000003133 243.0
TH1_k127_3167473_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1502.0
TH1_k127_3167473_1 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 1.16e-203 658.0
TH1_k127_3167473_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 523.0
TH1_k127_3167473_3 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 445.0
TH1_k127_3167473_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002653 265.0
TH1_k127_3167473_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000002372 127.0
TH1_k127_3231204_0 Protein of unknown function (DUF3604) - - - 6.669e-235 737.0
TH1_k127_3231204_1 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 380.0
TH1_k127_3231204_2 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 333.0
TH1_k127_3231204_3 - - - - 0.0000000000003798 70.0
TH1_k127_3253919_0 oxidoreductase activity - - - 0.0 1069.0
TH1_k127_3253919_1 AcrB/AcrD/AcrF family - - - 0.0 1018.0
TH1_k127_3253919_10 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 414.0
TH1_k127_3253919_11 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 363.0
TH1_k127_3253919_12 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 339.0
TH1_k127_3253919_13 Aminoacyl-tRNA editing domain K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000007412 238.0
TH1_k127_3253919_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000006236 218.0
TH1_k127_3253919_15 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000002316 220.0
TH1_k127_3253919_16 Thioesterase - - - 0.000000000000000000000000000000000000000000000000000000000000477 224.0
TH1_k127_3253919_17 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000003598 183.0
TH1_k127_3253919_18 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000005642 146.0
TH1_k127_3253919_19 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000000001074 127.0
TH1_k127_3253919_2 CoA binding domain - - - 6.345e-317 990.0
TH1_k127_3253919_20 Aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000531 128.0
TH1_k127_3253919_21 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.00000000000000000000004688 100.0
TH1_k127_3253919_22 Transcriptional regulator - - - 0.000000000000000173 81.0
TH1_k127_3253919_23 FAD linked oxidase domain protein K00103 - 1.1.3.8 0.00000000001859 78.0
TH1_k127_3253919_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 5.581e-262 831.0
TH1_k127_3253919_4 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 8.33e-210 659.0
TH1_k127_3253919_5 Acyl-CoA synthetase (NDP forming) K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 629.0
TH1_k127_3253919_6 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 589.0
TH1_k127_3253919_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 588.0
TH1_k127_3253919_8 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 502.0
TH1_k127_3253919_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 450.0
TH1_k127_3261795_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000005171 217.0
TH1_k127_3261795_1 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000000000000000000000000000000000000009976 211.0
TH1_k127_3261795_2 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000306 203.0
TH1_k127_3261795_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000006291 191.0
TH1_k127_3261795_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000002896 156.0
TH1_k127_3261795_5 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000002441 117.0
TH1_k127_3261795_6 ribonuclease, Rne Rng family K08301 - - 0.000000000000001175 77.0
TH1_k127_3334282_0 Oxidoreductase - - - 8.119e-219 693.0
TH1_k127_3334282_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 590.0
TH1_k127_3334282_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 364.0
TH1_k127_3334282_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000004458 207.0
TH1_k127_3334282_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000004251 61.0
TH1_k127_3344631_0 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000004626 239.0
TH1_k127_3344631_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000001137 224.0
TH1_k127_3344631_2 Uncharacterized protein conserved in bacteria (DUF2237) - - - 0.0000000000000000000000000000000000000000000000000128 184.0
TH1_k127_3344631_3 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000003594 127.0
TH1_k127_3344631_4 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000002521 80.0
TH1_k127_3344631_5 transcriptional regulator K03892 - - 0.000000000005066 78.0
TH1_k127_3355245_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 556.0
TH1_k127_3355245_1 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000387 105.0
TH1_k127_3355318_0 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 362.0
TH1_k127_3355318_1 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000007324 228.0
TH1_k127_3355318_2 - - - - 0.00000000000000000000000000005161 120.0
TH1_k127_3355318_3 - - - - 0.00000000000000000000764 99.0
TH1_k127_3355318_4 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000007641 98.0
TH1_k127_3355318_5 Lysin motif - - - 0.000000000000000001559 88.0
TH1_k127_3369440_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 310.0
TH1_k127_3369440_1 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000004353 178.0
TH1_k127_3369440_2 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000004208 174.0
TH1_k127_3369440_3 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000002386 157.0
TH1_k127_3369440_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000005241 164.0
TH1_k127_3425203_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.244e-202 640.0
TH1_k127_3425203_1 PFAM aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 463.0
TH1_k127_3425203_10 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000004609 198.0
TH1_k127_3425203_11 GGDEF domain - - - 0.000000000000000000000000000000000000003299 162.0
TH1_k127_3425203_12 Glycosyltransferase like family - - - 0.0000000000000000000000000000000000000101 162.0
TH1_k127_3425203_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000004748 138.0
TH1_k127_3425203_14 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000002056 87.0
TH1_k127_3425203_2 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 421.0
TH1_k127_3425203_3 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 409.0
TH1_k127_3425203_4 glucuronate isomerase K01812 - 5.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 351.0
TH1_k127_3425203_5 zinc protease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 334.0
TH1_k127_3425203_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000408 287.0
TH1_k127_3425203_7 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000003898 235.0
TH1_k127_3425203_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000007336 198.0
TH1_k127_3425203_9 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000004437 194.0
TH1_k127_3651267_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 376.0
TH1_k127_3651267_1 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001664 261.0
TH1_k127_3651267_2 Regulatory protein, FmdB family - - - 0.00000000000000000000000001353 113.0
TH1_k127_3653513_0 Protein of unknown function (DUF2867) - - - 1.892e-206 653.0
TH1_k127_3653513_1 FAD dependent oxidoreductase K06954 - - 9.642e-206 646.0
TH1_k127_3653513_10 PFAM BLUF domain protein - - - 0.00000000000000000000000000000000000000000000000001184 183.0
TH1_k127_3653513_11 Protein of unknown function (DUF2878) - - - 0.000000000000000000000000000000000000000000000001503 179.0
TH1_k127_3653513_12 COG0302 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000001227 68.0
TH1_k127_3653513_13 KR domain - - - 0.000000001043 59.0
TH1_k127_3653513_2 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 522.0
TH1_k127_3653513_3 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 505.0
TH1_k127_3653513_4 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 490.0
TH1_k127_3653513_5 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 397.0
TH1_k127_3653513_6 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 340.0
TH1_k127_3653513_7 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 305.0
TH1_k127_3653513_8 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 293.0
TH1_k127_3653513_9 Outer Membrane Lipoprotein K03098 - - 0.00000000000000000000000000000000000000000000000000000000000001992 233.0
TH1_k127_3654263_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 4.007e-234 739.0
TH1_k127_3654263_1 Pfam Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000000000000001164 165.0
TH1_k127_3654263_2 TonB C terminal K03646 - - 0.000000000000000000000000000000000001431 151.0
TH1_k127_3654263_3 - - - - 0.0000002744 63.0
TH1_k127_3655061_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 586.0
TH1_k127_3655061_1 Lanthionine synthetase C-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 333.0
TH1_k127_3655061_2 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 305.0
TH1_k127_3655061_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000007384 177.0
TH1_k127_3655061_4 amino acid ABC transporter K02029 - - 0.0000000000000000000000000000000002334 136.0
TH1_k127_3655061_5 - - - - 0.0000000000000000000000000000006944 124.0
TH1_k127_3655061_6 PEP-CTERM motif - - - 0.0009112 51.0
TH1_k127_36618_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1172.0
TH1_k127_36618_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 4.722e-300 938.0
TH1_k127_36618_10 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 429.0
TH1_k127_36618_11 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 350.0
TH1_k127_36618_12 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 312.0
TH1_k127_36618_13 Steryl acetyl hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 304.0
TH1_k127_36618_14 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 303.0
TH1_k127_36618_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 298.0
TH1_k127_36618_16 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003994 270.0
TH1_k127_36618_17 lipopolysaccharide heptosyltransferase I K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002616 267.0
TH1_k127_36618_18 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000004891 269.0
TH1_k127_36618_19 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000002787 241.0
TH1_k127_36618_2 type II and III secretion system protein K02666 - - 9.306e-212 681.0
TH1_k127_36618_20 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001336 242.0
TH1_k127_36618_21 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000004124 237.0
TH1_k127_36618_22 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000001699 210.0
TH1_k127_36618_23 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000135 205.0
TH1_k127_36618_24 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000000000000001571 203.0
TH1_k127_36618_25 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000008104 188.0
TH1_k127_36618_26 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000000000000000000000000000000005407 194.0
TH1_k127_36618_27 PGAP1-like protein - - - 0.0000000000000000000000000108 124.0
TH1_k127_36618_28 Rhodanese domain protein - - - 0.0000000000000000000000005194 117.0
TH1_k127_36618_29 mRNA catabolic process - - - 0.0000000000000000000000337 116.0
TH1_k127_36618_3 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 567.0
TH1_k127_36618_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 545.0
TH1_k127_36618_5 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 501.0
TH1_k127_36618_6 Type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 474.0
TH1_k127_36618_7 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 470.0
TH1_k127_36618_8 RmlD substrate binding domain K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 444.0
TH1_k127_36618_9 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 435.0
TH1_k127_3673563_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 314.0
TH1_k127_3673563_1 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000002656 215.0
TH1_k127_3673563_2 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000009347 161.0
TH1_k127_3673563_3 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000001968 84.0
TH1_k127_3673563_4 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000291 61.0
TH1_k127_3676708_0 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000003213 242.0
TH1_k127_3676708_1 membrane - - - 0.00000000000000000000000000000000000000000004501 171.0
TH1_k127_3677331_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.196e-268 839.0
TH1_k127_3677331_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.242e-256 798.0
TH1_k127_3677331_2 - - - - 0.0000000000000000000000000000000000000000000001006 178.0
TH1_k127_3677331_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000341 144.0
TH1_k127_368305_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 602.0
TH1_k127_368305_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009858 567.0
TH1_k127_368305_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 372.0
TH1_k127_368305_3 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 342.0
TH1_k127_368305_4 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 329.0
TH1_k127_368305_5 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 317.0
TH1_k127_368305_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002111 253.0
TH1_k127_368305_7 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000001498 210.0
TH1_k127_368305_8 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.00000000000000000000000000000000000000006707 152.0
TH1_k127_3685633_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 7.499e-230 734.0
TH1_k127_3685633_1 Glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 538.0
TH1_k127_3685633_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 518.0
TH1_k127_3685633_3 TIGRFAM histidinol-phosphate phosphatase family protein K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005778 270.0
TH1_k127_3685633_4 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000006178 255.0
TH1_k127_3685633_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000001317 206.0
TH1_k127_3685633_6 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000006719 175.0
TH1_k127_3685633_7 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.00000000000000000000000000001546 126.0
TH1_k127_3685633_8 Belongs to the frataxin family K06202 - - 0.00000000000000000000004634 105.0
TH1_k127_3691232_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1261.0
TH1_k127_3691232_1 4Fe-4S binding domain K18362 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 361.0
TH1_k127_3691232_2 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000001823 230.0
TH1_k127_3691232_3 DMSO reductase anchor subunit (DmsC) - - - 0.00000000000000000000000000000000000000000000000000000007353 207.0
TH1_k127_3691232_4 transcriptional regulator - - - 0.000000000000000000000000000000000000000000001893 191.0
TH1_k127_3691232_5 AMP-binding enzyme - - - 0.0000000000000001861 84.0
TH1_k127_3692638_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 476.0
TH1_k127_3692638_1 peptidase m48, ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 428.0
TH1_k127_3692638_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 411.0
TH1_k127_3692638_3 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 323.0
TH1_k127_3692638_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000001487 203.0
TH1_k127_3692638_5 Methyltransferase FkbM domain - - - 0.00000000000000001718 91.0
TH1_k127_3694194_0 Belongs to the IlvD Edd family - - - 5.504e-285 884.0
TH1_k127_3694194_1 glutamine synthetase K01915 - 6.3.1.2 3.973e-260 807.0
TH1_k127_3694194_10 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 428.0
TH1_k127_3694194_11 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 417.0
TH1_k127_3694194_12 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 376.0
TH1_k127_3694194_13 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 347.0
TH1_k127_3694194_14 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 339.0
TH1_k127_3694194_15 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 296.0
TH1_k127_3694194_16 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007994 286.0
TH1_k127_3694194_17 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000001608 247.0
TH1_k127_3694194_18 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000001129 185.0
TH1_k127_3694194_19 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000006236 169.0
TH1_k127_3694194_2 Peptidase family M3 K01414 - 3.4.24.70 3.263e-256 810.0
TH1_k127_3694194_21 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000000000000004582 149.0
TH1_k127_3694194_22 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000004634 141.0
TH1_k127_3694194_23 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000000000000000000000000002139 144.0
TH1_k127_3694194_24 protein involved in tolerance to divalent cations K03926 - - 0.00000000000000000000000000000000799 130.0
TH1_k127_3694194_25 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000009622 114.0
TH1_k127_3694194_26 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03830 - - 0.0000000000000000001546 95.0
TH1_k127_3694194_27 - - - - 0.0000000000006144 69.0
TH1_k127_3694194_28 Protein of unknown function (DUF3460) - - - 0.00000000001984 66.0
TH1_k127_3694194_29 Psort location CytoplasmicMembrane, score K07113 - - 0.00000000005404 69.0
TH1_k127_3694194_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.564e-245 767.0
TH1_k127_3694194_30 Domain of unknown function (DUF4124) - - - 0.0000000001358 74.0
TH1_k127_3694194_31 - - - - 0.000000008229 66.0
TH1_k127_3694194_4 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 5.91e-245 762.0
TH1_k127_3694194_5 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 3.356e-195 632.0
TH1_k127_3694194_6 Organic solvent tolerance protein K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 570.0
TH1_k127_3694194_7 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009029 437.0
TH1_k127_3694194_8 Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 438.0
TH1_k127_3694194_9 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 466.0
TH1_k127_3694827_0 Ferrous iron transport protein B K04759 - - 1.15e-199 640.0
TH1_k127_3694827_1 iron ion homeostasis K04758 - - 0.00000007376 56.0
TH1_k127_3694827_2 Outer membrane protein beta-barrel domain K03286 - - 0.000002602 49.0
TH1_k127_3699844_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 561.0
TH1_k127_3699844_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 549.0
TH1_k127_3699844_2 ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 391.0
TH1_k127_3699844_3 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 364.0
TH1_k127_3699844_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 319.0
TH1_k127_3699844_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003032 298.0
TH1_k127_3699844_6 toluene tolerance family protein K07323 - - 0.00000000000000000000000004247 108.0
TH1_k127_3699844_7 Belongs to the BolA IbaG family - - - 0.0000000000000000000005766 109.0
TH1_k127_3699844_8 STAS domain K07122 - - 0.00002493 53.0
TH1_k127_3708665_0 Oxidoreductase FAD-binding domain K02613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 488.0
TH1_k127_3708665_1 phenylacetic acid degradation protein paaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 422.0
TH1_k127_3708665_2 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000000000000000000000000001128 203.0
TH1_k127_3708665_3 Phenylacetic acid degradation K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000003865 160.0
TH1_k127_3714021_0 ABC-type dipeptide transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 523.0
TH1_k127_3714021_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000001457 239.0
TH1_k127_3733386_0 AcrB/AcrD/AcrF family - - - 0.0 1595.0
TH1_k127_3733386_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.607e-219 694.0
TH1_k127_3733386_10 metal-dependent hydrolase of the TIM-barrel fold K10221 - 3.1.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 499.0
TH1_k127_3733386_11 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04099,K04101 - 1.13.11.57,1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 467.0
TH1_k127_3733386_12 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 446.0
TH1_k127_3733386_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 434.0
TH1_k127_3733386_14 FAD linked oxidase K00104,K11472 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 411.0
TH1_k127_3733386_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 399.0
TH1_k127_3733386_16 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 366.0
TH1_k127_3733386_17 Histidine kinase K20975 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 379.0
TH1_k127_3733386_18 abc transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 361.0
TH1_k127_3733386_19 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 327.0
TH1_k127_3733386_2 Glycolate oxidase subunit GlcD K00104 - 1.1.3.15 4.34e-212 668.0
TH1_k127_3733386_20 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 321.0
TH1_k127_3733386_21 Pfam:Methyltransf_6 K10218 - 4.1.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 321.0
TH1_k127_3733386_22 Domain of unknown function (DUF1932) K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 305.0
TH1_k127_3733386_23 Transcriptional regulator K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 295.0
TH1_k127_3733386_24 Histidine kinase K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 282.0
TH1_k127_3733386_25 ABC transporter substrate binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001617 255.0
TH1_k127_3733386_26 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001228 242.0
TH1_k127_3733386_27 Protein of unknown function (DUF2652) - - - 0.000000000000000000000000000000000000000000000000000000000000000000375 236.0
TH1_k127_3733386_28 COG3119 Arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000002079 236.0
TH1_k127_3733386_29 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000006415 226.0
TH1_k127_3733386_3 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 607.0
TH1_k127_3733386_30 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000003489 223.0
TH1_k127_3733386_31 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000004996 216.0
TH1_k127_3733386_32 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000001983 205.0
TH1_k127_3733386_33 Protocatechuate 4,5-dioxygenase K04100 - 1.13.11.8 0.00000000000000000000000000000000000000000000000000002249 191.0
TH1_k127_3733386_34 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000003846 185.0
TH1_k127_3733386_35 acetyltransferase - - - 0.00000000000000000000000000000000000001008 153.0
TH1_k127_3733386_36 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000000000007162 105.0
TH1_k127_3733386_37 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000003652 91.0
TH1_k127_3733386_38 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000002356 83.0
TH1_k127_3733386_39 addiction module antidote protein - - - 0.0000000000006306 71.0
TH1_k127_3733386_4 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 604.0
TH1_k127_3733386_40 ATP-independent chaperone mediated protein folding - - - 0.0000000313 62.0
TH1_k127_3733386_5 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 571.0
TH1_k127_3733386_6 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 537.0
TH1_k127_3733386_7 PrpF protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 532.0
TH1_k127_3733386_8 glycolate oxidase iron-sulfur subunit K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 524.0
TH1_k127_3733386_9 Extracellular liganD-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 516.0
TH1_k127_3747436_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 554.0
TH1_k127_3747436_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 464.0
TH1_k127_3747436_2 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 452.0
TH1_k127_3747436_3 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 309.0
TH1_k127_3747436_4 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009428 255.0
TH1_k127_3754951_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1018.0
TH1_k127_3763797_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 8.16e-271 842.0
TH1_k127_3763797_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 436.0
TH1_k127_3763797_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 326.0
TH1_k127_3763797_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006875 259.0
TH1_k127_3763797_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000008253 247.0
TH1_k127_3763797_5 Thioesterase superfamily protein K10806 - - 0.000000000000000000000000000000000000000000000848 179.0
TH1_k127_3763797_6 - - - - 0.00000000000000000000000006594 114.0
TH1_k127_3763797_7 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000003554 87.0
TH1_k127_3763797_8 Chalcone isomerase-like - - - 0.00000000000000006966 85.0
TH1_k127_3765995_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1329.0
TH1_k127_3765995_1 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 418.0
TH1_k127_3765995_2 acetylornithine aminotransferase K00821,K00840 GO:0003674,GO:0003824,GO:0003992,GO:0004069,GO:0005488,GO:0005515,GO:0006082,GO:0006105,GO:0006520,GO:0006525,GO:0006526,GO:0006527,GO:0006553,GO:0006591,GO:0006593,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009016,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009067,GO:0009084,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0017144,GO:0019545,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0036094,GO:0042450,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043825,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.11,2.6.1.17,2.6.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 367.0
TH1_k127_3765995_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 337.0
TH1_k127_3765995_4 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000002699 141.0
TH1_k127_3769941_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 518.0
TH1_k127_3769941_1 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 420.0
TH1_k127_3769941_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 303.0
TH1_k127_377875_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1058.0
TH1_k127_377875_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 464.0
TH1_k127_377875_10 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000002465 263.0
TH1_k127_377875_11 SmpB protein K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000001578 232.0
TH1_k127_377875_12 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000002807 228.0
TH1_k127_377875_13 dna polymerase iii K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000006344 241.0
TH1_k127_377875_14 general secretion pathway protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000002613 213.0
TH1_k127_377875_15 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000001726 195.0
TH1_k127_377875_16 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000008744 184.0
TH1_k127_377875_17 NLP P60 protein - - - 0.000000000000000000000000000000000000000000006598 175.0
TH1_k127_377875_18 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000006446 160.0
TH1_k127_377875_19 Ankyrin repeat K06867 - - 0.0000000000000000000000000000000000000000008846 167.0
TH1_k127_377875_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 449.0
TH1_k127_377875_20 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000000000000000000000002239 112.0
TH1_k127_377875_21 Type II secretion system (T2SS), protein I K02458 - - 0.00000000000000000001919 102.0
TH1_k127_377875_22 PFAM General secretion pathway L K02461 - - 0.00000000000002646 85.0
TH1_k127_377875_23 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000003753 70.0
TH1_k127_377875_24 general secretion pathway protein K02457 - - 0.000000000006424 75.0
TH1_k127_377875_25 General Secretory Pathway K02463 - - 0.00000000001031 74.0
TH1_k127_377875_26 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000009095 71.0
TH1_k127_377875_27 Type II secretion system (T2SS), protein M - - - 0.000009895 55.0
TH1_k127_377875_3 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 373.0
TH1_k127_377875_4 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 357.0
TH1_k127_377875_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 352.0
TH1_k127_377875_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 339.0
TH1_k127_377875_7 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 319.0
TH1_k127_377875_8 squalene-associated FAD-dependent desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007314 286.0
TH1_k127_377875_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001059 258.0
TH1_k127_3779102_0 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 8.902e-253 811.0
TH1_k127_3779102_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 455.0
TH1_k127_3779102_2 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 429.0
TH1_k127_3779102_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 291.0
TH1_k127_3779102_4 Modulator of DNA gyrase K03568 - - 0.00000000000000002097 81.0
TH1_k127_3784143_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 5.206e-309 970.0
TH1_k127_3784143_1 Aromatic amino acid lyase - - - 8.632e-195 623.0
TH1_k127_3784143_2 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 381.0
TH1_k127_3784143_3 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000005279 249.0
TH1_k127_3784143_4 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000129 194.0
TH1_k127_3784143_5 - - - - 0.00000000000000000000000001432 115.0
TH1_k127_3785301_0 PFAM CBS domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 378.0
TH1_k127_3785301_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000004112 129.0
TH1_k127_3785301_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000004873 79.0
TH1_k127_3793396_0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II - - - 2.024e-199 640.0
TH1_k127_3793396_1 Radical SAM superfamily K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 544.0
TH1_k127_3793396_2 Quinohemoprotein amine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 412.0
TH1_k127_3793396_3 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 410.0
TH1_k127_3793396_4 peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005487 272.0
TH1_k127_3793396_5 COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain K06147,K20344 - - 0.000000000000000000000000000000000000000000000000000000000000000928 226.0
TH1_k127_3793396_6 Quinohemoprotein amine dehydrogenase, gamma subunit - - - 0.00000000000000000000000000000000000000000000000003172 189.0
TH1_k127_3794585_0 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 623.0
TH1_k127_3796758_0 antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 539.0
TH1_k127_3796758_1 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 542.0
TH1_k127_3796758_2 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 350.0
TH1_k127_3796758_3 CHASE2 K01768,K01769 - 4.6.1.1,4.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000003614 266.0
TH1_k127_3796758_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000006764 223.0
TH1_k127_3796758_5 TIGRFAM outer membrane autotransporter barrel - - - 0.000000000000000000000000000000005662 144.0
TH1_k127_3796758_6 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000005317 104.0
TH1_k127_3804627_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.658e-205 650.0
TH1_k127_3807948_0 Malic enzyme K00029 - 1.1.1.40 0.0 1073.0
TH1_k127_3807948_1 Phenol hydroxylase, C-terminal dimerisation domain K03380 - 1.14.13.7 1.726e-299 933.0
TH1_k127_3807948_10 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000000000122 148.0
TH1_k127_3807948_11 Cold-shock DNA-binding domain protein K03704 - - 0.00000000000000000000000000000000059 130.0
TH1_k127_3807948_12 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000005409 81.0
TH1_k127_3807948_13 Helix-turn-helix domain K15773 - - 0.00000000002651 68.0
TH1_k127_3807948_14 - - - - 0.0002151 49.0
TH1_k127_3807948_2 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 3.731e-291 902.0
TH1_k127_3807948_3 O-methyltransferase activity - - - 1.94e-209 671.0
TH1_k127_3807948_4 HipA N-terminal domain K07154 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 562.0
TH1_k127_3807948_5 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 411.0
TH1_k127_3807948_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 379.0
TH1_k127_3807948_7 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 319.0
TH1_k127_3807948_8 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 291.0
TH1_k127_3807948_9 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000003398 267.0
TH1_k127_3808756_0 Pyridoxal-phosphate dependent enzyme - - - 1.803e-200 629.0
TH1_k127_3808756_1 Flavocytochrome c sulphide dehydrogenase, flavin-binding K05301,K17218 - 1.8.2.1,1.8.5.4 2.221e-199 629.0
TH1_k127_3808756_2 Isocitrate lyase K01637 - 4.1.3.1 9.519e-195 614.0
TH1_k127_3808756_3 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 557.0
TH1_k127_3808756_4 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 516.0
TH1_k127_3808756_5 Virulence factor BrkB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 363.0
TH1_k127_3808756_6 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000009845 236.0
TH1_k127_3808756_7 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000000000000007059 215.0
TH1_k127_3808756_8 Methyltransferase K02553 - - 0.000000000000000000000000000000000003927 138.0
TH1_k127_3808756_9 Cytochrome c, class I - - - 0.000000000000000000000000000528 122.0
TH1_k127_3848866_0 KR domain K00034 - 1.1.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001395 285.0
TH1_k127_3848866_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000001349 73.0
TH1_k127_3860425_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 535.0
TH1_k127_3860425_1 membrane protein, TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 490.0
TH1_k127_3860425_10 Sensors of blue-light using FAD - - - 0.0000000000000000000001116 102.0
TH1_k127_3860425_11 COGs COG2929 conserved K09803 - - 0.000000000000000000001058 95.0
TH1_k127_3860425_12 PFAM regulatory protein, MerR K22491 - - 0.0000000000001814 83.0
TH1_k127_3860425_2 Bacterial regulatory helix-turn-helix protein, lysR family K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 415.0
TH1_k127_3860425_3 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 374.0
TH1_k127_3860425_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 360.0
TH1_k127_3860425_5 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000622 220.0
TH1_k127_3860425_6 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000005945 213.0
TH1_k127_3860425_7 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.000000000000000000000000000000000000000000000000003342 185.0
TH1_k127_3860425_8 Universal stress protein - - - 0.000000000000000000000000001804 116.0
TH1_k127_3860425_9 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000243 111.0
TH1_k127_3889659_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 8.194e-233 739.0
TH1_k127_3889659_1 Transketolase, C-terminal domain K00167 - 1.2.4.4 3.011e-199 623.0
TH1_k127_3889659_2 Dehydrogenase E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 615.0
TH1_k127_3889659_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 534.0
TH1_k127_3889659_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 511.0
TH1_k127_3889659_5 FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 392.0
TH1_k127_3889659_6 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 364.0
TH1_k127_3889659_7 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K09699 - 2.3.1.168 0.00000000000000000000000000001048 121.0
TH1_k127_3889659_8 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000001785 68.0
TH1_k127_3889659_9 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000002203 57.0
TH1_k127_3903680_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1108.0
TH1_k127_3903680_1 Required for chromosome condensation and partitioning K03529 - - 1.088e-285 922.0
TH1_k127_3903680_10 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 433.0
TH1_k127_3903680_11 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 409.0
TH1_k127_3903680_12 Protein of unknown function (DUF2817) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 408.0
TH1_k127_3903680_13 Transcriptional regulator, LysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 350.0
TH1_k127_3903680_14 PFAM PHP C-terminal K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 317.0
TH1_k127_3903680_15 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 317.0
TH1_k127_3903680_16 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000001486 209.0
TH1_k127_3903680_17 methyltransferase K03437 - - 0.0000000000000000000000000000000000000000000000000000001773 207.0
TH1_k127_3903680_18 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000000000000000000000003687 194.0
TH1_k127_3903680_19 transcriptional regulator, XRE family - - - 0.0000000000000000000000000000000000000000001054 163.0
TH1_k127_3903680_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.325e-275 862.0
TH1_k127_3903680_20 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000000000004232 130.0
TH1_k127_3903680_21 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.00000000000000000000000000002011 118.0
TH1_k127_3903680_22 TPM domain - - - 0.00000000000000000000000187 108.0
TH1_k127_3903680_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 1.109e-273 850.0
TH1_k127_3903680_4 PFAM extracellular solute-binding protein, family 5 K02035 - - 8.589e-246 769.0
TH1_k127_3903680_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 2.275e-220 689.0
TH1_k127_3903680_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.72e-196 621.0
TH1_k127_3903680_7 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 505.0
TH1_k127_3903680_8 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 455.0
TH1_k127_3903680_9 N-terminal TM domain of oligopeptide transport permease C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 441.0
TH1_k127_3912055_0 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 414.0
TH1_k127_3912055_1 Glycosyl transferases group 1 K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 339.0
TH1_k127_3912055_2 VanZ like family - - - 0.00000000000000000000000000000000000000000309 169.0
TH1_k127_3912055_3 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.000000000000000000000000000000000004529 138.0
TH1_k127_3912055_4 Aluminium induced protein K01953 - 6.3.5.4 0.000000000000000000000000006671 113.0
TH1_k127_3915648_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 469.0
TH1_k127_3915648_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 454.0
TH1_k127_3915648_10 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000001527 195.0
TH1_k127_3915648_11 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000001021 174.0
TH1_k127_3915648_12 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000001141 168.0
TH1_k127_3915648_13 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000002105 157.0
TH1_k127_3915648_14 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000000003407 148.0
TH1_k127_3915648_15 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000001774 148.0
TH1_k127_3915648_16 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000004622 122.0
TH1_k127_3915648_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000001279 63.0
TH1_k127_3915648_18 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000003806 68.0
TH1_k127_3915648_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 367.0
TH1_k127_3915648_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 310.0
TH1_k127_3915648_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 313.0
TH1_k127_3915648_5 50S ribosomal protein L4 K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004422 291.0
TH1_k127_3915648_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004755 247.0
TH1_k127_3915648_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005047 245.0
TH1_k127_3915648_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000001428 218.0
TH1_k127_3915648_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000001651 214.0
TH1_k127_3924386_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 7.042e-306 962.0
TH1_k127_3924386_1 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 399.0
TH1_k127_3924386_10 Belongs to the HypD family K04654 - - 0.00000000000000001931 83.0
TH1_k127_3924386_11 Rubredoxin - - - 0.000000000000001399 86.0
TH1_k127_3924386_2 PFAM HupH hydrogenase expression protein K03618 - - 0.000000000000000000000000000000000000000000000000000000000000001079 235.0
TH1_k127_3924386_3 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000000000000000000003051 221.0
TH1_k127_3924386_4 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000001904 205.0
TH1_k127_3924386_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000000000001141 138.0
TH1_k127_3924386_6 Hydrogenase-1 expression protein HyaE K03619 - - 0.0000000000000000000000000000003372 128.0
TH1_k127_3924386_7 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.00000000000000000000000000002846 128.0
TH1_k127_3924386_8 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000000005318 109.0
TH1_k127_3924386_9 HupF/HypC family K04653 - - 0.0000000000000000000006917 102.0
TH1_k127_3945446_0 candidate b-glycosidase, glycoside hydrolase family 8 protein - - - 0.000000000000000000000000000000000000000000000002357 190.0
TH1_k127_3968361_0 Cytochrome D1 heme domain - - - 6.204e-226 719.0
TH1_k127_3968361_1 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 546.0
TH1_k127_3998965_0 4Fe-4S dicluster domain - - - 0.0 1467.0
TH1_k127_3998965_1 Tripartite tricarboxylate transporter TctA family K07793 - - 4.532e-288 893.0
TH1_k127_3998965_10 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 380.0
TH1_k127_3998965_11 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 369.0
TH1_k127_3998965_12 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 317.0
TH1_k127_3998965_13 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 299.0
TH1_k127_3998965_14 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007552 246.0
TH1_k127_3998965_15 Tripartite ATP-independent periplasmic transporter dctq component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001286 251.0
TH1_k127_3998965_16 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000392 160.0
TH1_k127_3998965_17 molybdate-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.0000000000000000001645 102.0
TH1_k127_3998965_2 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 3.078e-239 755.0
TH1_k127_3998965_3 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 1.935e-217 680.0
TH1_k127_3998965_4 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 610.0
TH1_k127_3998965_5 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 603.0
TH1_k127_3998965_6 Carbohydrate transport and metabolism K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 613.0
TH1_k127_3998965_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 572.0
TH1_k127_3998965_8 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 441.0
TH1_k127_3998965_9 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 422.0
TH1_k127_4004673_0 ATP-dependent Clp protease ATP-binding subunit K03694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 481.0
TH1_k127_4004673_1 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 285.0
TH1_k127_4004673_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000001579 198.0
TH1_k127_4004673_3 -acetyltransferase K03828,K17840 - 2.3.1.59 0.0000000000003467 74.0
TH1_k127_4007175_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 7.728e-264 829.0
TH1_k127_4007175_1 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 5.557e-245 769.0
TH1_k127_4007175_10 Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007975 413.0
TH1_k127_4007175_11 Glycosyl Transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 370.0
TH1_k127_4007175_12 Glycosyl transferase K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 383.0
TH1_k127_4007175_13 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 367.0
TH1_k127_4007175_14 O-antigen ligase like membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 327.0
TH1_k127_4007175_15 response regulator K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 296.0
TH1_k127_4007175_16 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000148 304.0
TH1_k127_4007175_17 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002863 266.0
TH1_k127_4007175_18 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000001694 242.0
TH1_k127_4007175_19 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000121 235.0
TH1_k127_4007175_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.707e-216 683.0
TH1_k127_4007175_20 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000003392 213.0
TH1_k127_4007175_21 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000003804 222.0
TH1_k127_4007175_22 PFAM NAD-dependent epimerase dehydratase K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000003782 200.0
TH1_k127_4007175_23 HNH nucleases - - - 0.0000000000000000000000000000000000000000000007092 172.0
TH1_k127_4007175_24 O-acyltransferase activity - - - 0.0000000000000000000000000000000000000000001743 179.0
TH1_k127_4007175_25 shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000001965 161.0
TH1_k127_4007175_26 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000001358 142.0
TH1_k127_4007175_27 Glu-tRNAGln amidotransferase C subunit - - - 0.00000000000000000000000003285 112.0
TH1_k127_4007175_28 - - - - 0.0000000007448 61.0
TH1_k127_4007175_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 9.638e-213 671.0
TH1_k127_4007175_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.671e-210 673.0
TH1_k127_4007175_5 Rod shape-determining protein MreB K03569 - - 2.848e-196 619.0
TH1_k127_4007175_6 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 516.0
TH1_k127_4007175_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 479.0
TH1_k127_4007175_8 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 461.0
TH1_k127_4007175_9 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 464.0
TH1_k127_4040379_0 FIST C domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 435.0
TH1_k127_4040379_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000006937 172.0
TH1_k127_4052242_0 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 539.0
TH1_k127_4052242_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 499.0
TH1_k127_4052242_2 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000003804 203.0
TH1_k127_4052242_3 Subtilase family - - - 0.00000000000000000000000000000000000000000000000001198 185.0
TH1_k127_4062024_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.75e-204 645.0
TH1_k127_4062024_1 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 451.0
TH1_k127_4062024_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 436.0
TH1_k127_4062024_3 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000009041 169.0
TH1_k127_4077274_0 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 451.0
TH1_k127_4077274_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 310.0
TH1_k127_4077274_2 glycosyl transferase family 2 K20444 - - 0.0000000000000001973 80.0
TH1_k127_4102436_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 522.0
TH1_k127_4102436_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 400.0
TH1_k127_4102436_2 Solute carrier family 35 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 298.0
TH1_k127_4102436_3 Protein of unknown function (DUF465) - - - 0.0000000007459 72.0
TH1_k127_4107196_0 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000005859 220.0
TH1_k127_4107196_1 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000001053 198.0
TH1_k127_4107196_2 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.000000000000000000000000000000000000000000000000000006022 194.0
TH1_k127_4109440_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 2.201e-261 827.0
TH1_k127_4109440_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 479.0
TH1_k127_4109440_2 HD domain K13815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 371.0
TH1_k127_4109440_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000001513 196.0
TH1_k127_4109440_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000001418 175.0
TH1_k127_4109440_5 PFAM regulatory protein, MerR - - - 0.000000000000000000000000000000000000000000005048 171.0
TH1_k127_4109440_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000003126 99.0
TH1_k127_4109440_7 Belongs to the 'phage' integrase family - - - 0.000008618 52.0
TH1_k127_4118677_0 Polysaccharide biosynthesis protein K15894,K17716 - 4.2.1.115,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 303.0
TH1_k127_4118677_1 DNA replication protein - - - 0.00000000000000000000000000000000000000000000000000000004674 209.0
TH1_k127_4118677_2 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000014 195.0
TH1_k127_4118677_3 Vibrio cholerae RfbT protein - - - 0.0000000000000000009076 93.0
TH1_k127_4148738_0 - - - - 0.0000000000000000000000000000000000000000000000000006436 192.0
TH1_k127_4148738_1 - - - - 0.00000000000000000000000000000009488 128.0
TH1_k127_4148738_2 Transglycosylase associated protein - - - 0.00000000000000000003474 92.0
TH1_k127_4163272_0 Type II secretion system protein K K02460 - - 0.00000000000000000000000000000000000000000000001773 185.0
TH1_k127_4163272_1 fimbrial assembly K02461 - - 0.0000000000000000000000000188 122.0
TH1_k127_4163272_2 General secretion pathway protein K02459 - - 0.000000000000000000000000469 113.0
TH1_k127_4249128_0 ABC transporter K06020 - 3.6.3.25 4.404e-289 895.0
TH1_k127_4249128_1 ABC transporter K06158 - - 1.091e-215 687.0
TH1_k127_4249128_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.202e-210 670.0
TH1_k127_4249128_3 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 593.0
TH1_k127_4249128_4 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 548.0
TH1_k127_4249128_5 Major facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 511.0
TH1_k127_4249128_6 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 368.0
TH1_k127_4249128_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003374 287.0
TH1_k127_4249128_8 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001146 250.0
TH1_k127_4249128_9 Domain of unknown function (DUF4124) - - - 0.00000000000000000000002198 113.0
TH1_k127_4263848_0 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 312.0
TH1_k127_4263848_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007865 267.0
TH1_k127_4263848_2 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008917 281.0
TH1_k127_4263848_3 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.00000000000000000000000000000004825 146.0
TH1_k127_4263848_4 antisigma factor binding K04749,K06378 - - 0.00000000000000000000000000009457 129.0
TH1_k127_4306662_0 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 534.0
TH1_k127_4306662_1 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 516.0
TH1_k127_4306662_2 N-terminal TM domain of oligopeptide transport permease C K02034,K12370 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 452.0
TH1_k127_4306662_3 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.000000000000000000000000000000000000000000000000000007731 194.0
TH1_k127_4311611_0 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000879 379.0
TH1_k127_4311611_1 COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001588 285.0
TH1_k127_4311611_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000000000000000000007329 154.0
TH1_k127_4311611_3 positive regulation of growth - GO:0006417,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0040007,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0080090,GO:2000112 - 0.0000000001919 64.0
TH1_k127_4311611_4 to nucleic acid-binding protein contains PIN domain - - - 0.0001808 48.0
TH1_k127_4381392_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 2.663e-204 646.0
TH1_k127_4381392_1 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01032 - 2.8.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 431.0
TH1_k127_4381392_2 Aldolase K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003251 274.0
TH1_k127_4382145_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 2.501e-273 857.0
TH1_k127_4382145_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.051e-234 738.0
TH1_k127_4382145_10 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001685 279.0
TH1_k127_4382145_11 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004397 245.0
TH1_k127_4382145_12 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000001445 230.0
TH1_k127_4382145_13 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000001171 210.0
TH1_k127_4382145_14 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000004131 186.0
TH1_k127_4382145_15 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000004859 186.0
TH1_k127_4382145_16 - - - - 0.00000000000000000000000000000000000000000000005206 175.0
TH1_k127_4382145_17 Protein of unknown function (DUF3667) - - - 0.0000000000000000000000000000000000000001055 162.0
TH1_k127_4382145_18 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000003291 154.0
TH1_k127_4382145_19 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000004636 155.0
TH1_k127_4382145_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.376e-215 674.0
TH1_k127_4382145_20 Fe-S assembly protein IscX - - - 0.000000000000000000000000002462 113.0
TH1_k127_4382145_21 - - - - 0.0000000000000000000001072 108.0
TH1_k127_4382145_22 - - - - 0.00000000000000000004338 96.0
TH1_k127_4382145_23 endonuclease activity - - - 0.000000000000005589 81.0
TH1_k127_4382145_3 TRAP-type C4-dicarboxylate transport system, large permease - - - 8.496e-194 612.0
TH1_k127_4382145_4 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 598.0
TH1_k127_4382145_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 449.0
TH1_k127_4382145_6 Belongs to the HAD-like hydrolase superfamily. PhnX family K05306 - 3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 413.0
TH1_k127_4382145_7 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 367.0
TH1_k127_4382145_8 serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 354.0
TH1_k127_4382145_9 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 327.0
TH1_k127_4449276_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.962e-209 662.0
TH1_k127_4449276_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 508.0
TH1_k127_4449276_2 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 407.0
TH1_k127_4449276_3 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 371.0
TH1_k127_4449276_4 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 342.0
TH1_k127_4449276_5 Acyl-ACP thioesterase - - - 0.000000000000000000000000000000000000001755 160.0
TH1_k127_4462478_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 416.0
TH1_k127_4462478_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 316.0
TH1_k127_4462478_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000003678 158.0
TH1_k127_4462478_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000009529 141.0
TH1_k127_4462478_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000007546 141.0
TH1_k127_4472660_0 ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1122.0
TH1_k127_4472660_1 Isocitrate/isopropylmalate dehydrogenase K00052 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 434.0
TH1_k127_4472660_10 protein conserved in bacteria K09989 - - 0.000000000000000000000000000000000002294 139.0
TH1_k127_4472660_11 Anaerobic ribonucleoside-triphosphate reductase - - - 0.000000000000000000002078 95.0
TH1_k127_4472660_12 Trap-type c4-dicarboxylate transport system, small permease component K11689,K21394 - - 0.000000286 59.0
TH1_k127_4472660_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 422.0
TH1_k127_4472660_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 394.0
TH1_k127_4472660_4 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 388.0
TH1_k127_4472660_5 Fructosamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009973 317.0
TH1_k127_4472660_6 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000385 282.0
TH1_k127_4472660_7 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000108 249.0
TH1_k127_4472660_8 ribonucleoside-triphosphate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000005437 241.0
TH1_k127_4472660_9 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000000000000008324 169.0
TH1_k127_4567674_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0 1022.0
TH1_k127_4567674_1 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00122 - 1.17.1.9 5.018e-249 784.0
TH1_k127_4567674_2 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 556.0
TH1_k127_4567674_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 338.0
TH1_k127_456939_0 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005806 283.0
TH1_k127_456939_1 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001229 263.0
TH1_k127_456939_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005782 261.0
TH1_k127_456939_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000004054 173.0
TH1_k127_456939_4 PFAM GCN5-related N-acetyltransferase K06976 - - 0.0000000000000000000000000000001188 139.0
TH1_k127_4577227_0 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 491.0
TH1_k127_4577227_1 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000001428 261.0
TH1_k127_4577227_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000003421 146.0
TH1_k127_4577227_3 Lysin motif - - - 0.00000000000000000000000002205 121.0
TH1_k127_461343_0 AAA ATPase domain - - - 3.684e-253 818.0
TH1_k127_461343_1 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 2.285e-217 687.0
TH1_k127_461343_10 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006121 250.0
TH1_k127_461343_11 - - - - 0.0000000004463 62.0
TH1_k127_461343_12 - - - - 0.000001373 50.0
TH1_k127_461343_2 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 504.0
TH1_k127_461343_3 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 481.0
TH1_k127_461343_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 456.0
TH1_k127_461343_5 phosphate transport system K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 441.0
TH1_k127_461343_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 437.0
TH1_k127_461343_7 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 419.0
TH1_k127_461343_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 344.0
TH1_k127_461343_9 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 319.0
TH1_k127_469351_0 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 4.671e-207 647.0
TH1_k127_469351_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 423.0
TH1_k127_469351_2 membrane - - - 0.0000000000000000000000000000000000000001278 155.0
TH1_k127_469351_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000007168 119.0
TH1_k127_479326_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 513.0
TH1_k127_479326_1 homoserine dehydrogenase - - - 0.00000000000005562 72.0
TH1_k127_4873942_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 3.574e-307 952.0
TH1_k127_4873942_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.233e-278 870.0
TH1_k127_4873942_10 rRNA small subunit methyltransferase G K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000005559 216.0
TH1_k127_4873942_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.00000000000000000000000000000000000000000000000000251 186.0
TH1_k127_4873942_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000005118 167.0
TH1_k127_4873942_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000000007132 147.0
TH1_k127_4873942_14 Thioredoxin-like - - - 0.000000000000000000000000000000003748 136.0
TH1_k127_4873942_15 ThiS family K03636 - - 0.000000000000000000207 91.0
TH1_k127_4873942_16 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.0000000000000000009777 87.0
TH1_k127_4873942_17 ATP synthase I chain K02116 - - 0.00000000000000008629 85.0
TH1_k127_4873942_2 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 565.0
TH1_k127_4873942_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 393.0
TH1_k127_4873942_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 380.0
TH1_k127_4873942_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 365.0
TH1_k127_4873942_6 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 343.0
TH1_k127_4873942_7 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 334.0
TH1_k127_4873942_8 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000001822 257.0
TH1_k127_4873942_9 pfkB family carbohydrate kinase K00852,K18478 - 2.7.1.15,2.7.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000004525 262.0
TH1_k127_4875560_0 Orn/Lys/Arg decarboxylase, N-terminal domain - - - 1.989e-218 680.0
TH1_k127_4875560_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000956 598.0
TH1_k127_4875560_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 529.0
TH1_k127_4875560_3 taurine ABC transporter, periplasmic binding protein K15551 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 433.0
TH1_k127_4875560_4 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 431.0
TH1_k127_4875560_5 binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 417.0
TH1_k127_4875560_6 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K10831 - 3.6.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 400.0
TH1_k127_4875560_7 - - - - 0.00000004934 65.0
TH1_k127_4878449_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.393e-224 715.0
TH1_k127_4878449_1 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 461.0
TH1_k127_4878449_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 372.0
TH1_k127_4878449_3 transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 344.0
TH1_k127_4878449_5 Transposase domain (DUF772) - - - 0.0000000000000000000000000002722 114.0
TH1_k127_4878449_6 ABC transporter substrate binding protein K01989 - - 0.00006045 46.0
TH1_k127_4878449_7 Putative transposase - - - 0.00008545 51.0
TH1_k127_4879312_0 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 324.0
TH1_k127_4879312_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000001079 132.0
TH1_k127_4879312_2 Helix-turn-helix domain K07726 - - 0.00000000000000000000000000002471 119.0
TH1_k127_4879312_3 Protein of unknown function (DUF2283) - - - 0.0000000001328 64.0
TH1_k127_4879312_4 - - - - 0.0000007649 56.0
TH1_k127_4879312_5 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.0001227 51.0
TH1_k127_4892649_0 Aminotransferase K14261 - - 4.421e-214 670.0
TH1_k127_4892649_1 homoserine dehydrogenase K00003 - 1.1.1.3 1.262e-207 654.0
TH1_k127_4892649_10 Peptidase C13 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000009358 251.0
TH1_k127_4892649_11 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000009201 200.0
TH1_k127_4892649_12 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000003223 186.0
TH1_k127_4892649_13 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000002318 133.0
TH1_k127_4892649_14 plastoquinol--plastocyanin reductase activity - - - 0.0004026 45.0
TH1_k127_4892649_2 Threonine synthase K01733 - 4.2.3.1 5.714e-203 664.0
TH1_k127_4892649_3 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 467.0
TH1_k127_4892649_4 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 403.0
TH1_k127_4892649_5 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 391.0
TH1_k127_4892649_6 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 357.0
TH1_k127_4892649_7 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 307.0
TH1_k127_4892649_8 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 312.0
TH1_k127_4892649_9 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 286.0
TH1_k127_4900466_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 6.122e-198 625.0
TH1_k127_4900466_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 367.0
TH1_k127_4900466_10 PKD domain containing protein - - - 0.0001914 55.0
TH1_k127_4900466_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 320.0
TH1_k127_4900466_3 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 323.0
TH1_k127_4900466_4 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000000004081 217.0
TH1_k127_4900466_5 HYR domain - - - 0.00000000000000000000003203 117.0
TH1_k127_4900466_6 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000005583 89.0
TH1_k127_4900466_7 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000001663 83.0
TH1_k127_4900466_8 Right handed beta helix region - - - 0.0000000000000523 87.0
TH1_k127_4924119_0 asparagine K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 633.0
TH1_k127_4924119_1 glycosyl transferase K16701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 390.0
TH1_k127_4924119_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 384.0
TH1_k127_4924119_3 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001057 237.0
TH1_k127_4938663_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1067.0
TH1_k127_4938663_1 Domain of unknown function (DUF2088) - - - 1.32e-197 626.0
TH1_k127_4938663_10 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000000004921 209.0
TH1_k127_4938663_11 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000005626 166.0
TH1_k127_4938663_12 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000000000000000000000000001697 173.0
TH1_k127_4938663_13 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000000000000000000000002966 154.0
TH1_k127_4938663_14 Predicted integral membrane protein (DUF2282) - - - 0.000000000000000000000000000000000002463 141.0
TH1_k127_4938663_15 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000001638 142.0
TH1_k127_4938663_16 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000007351 135.0
TH1_k127_4938663_18 prlF antitoxin for toxin YhaV_toxin - - - 0.00000000000000000007125 91.0
TH1_k127_4938663_2 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 498.0
TH1_k127_4938663_3 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 397.0
TH1_k127_4938663_4 MCM2/3/5 family K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 386.0
TH1_k127_4938663_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 348.0
TH1_k127_4938663_6 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 349.0
TH1_k127_4938663_7 TIGRFAM TIGR00268 family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 294.0
TH1_k127_4938663_8 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000005601 249.0
TH1_k127_4938663_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000001282 235.0
TH1_k127_4956827_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 561.0
TH1_k127_4956827_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 333.0
TH1_k127_4956827_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001656 278.0
TH1_k127_4956827_3 PFAM Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.000000000000000000000000000000296 125.0
TH1_k127_4956827_4 Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism K13932 - 4.1.1.87 0.00000000000000000009093 104.0
TH1_k127_4977794_0 TIGRFAM arginyl-tRNA synthetase K01887 - 6.1.1.19 5.895e-207 657.0
TH1_k127_4977794_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 300.0
TH1_k127_4977794_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 293.0
TH1_k127_4977794_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000007907 199.0
TH1_k127_4977794_4 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000002715 181.0
TH1_k127_4977794_5 Sporulation related domain - - - 0.000000000000000000000005012 113.0
TH1_k127_5010503_0 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 351.0
TH1_k127_5010503_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 293.0
TH1_k127_5010778_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1446.0
TH1_k127_5010778_1 Dehydrogenase K00382 - 1.8.1.4 7.18e-279 868.0
TH1_k127_5010778_10 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000000000000000008614 198.0
TH1_k127_5010778_11 - - - - 0.0000000000000000000000000000000000000000000006867 174.0
TH1_k127_5010778_12 Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors K12973 - 2.3.1.251 0.0000000000000000000000000000000000000003004 156.0
TH1_k127_5010778_14 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.00000000000000000000000001036 128.0
TH1_k127_5010778_15 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000003842 98.0
TH1_k127_5010778_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.27e-222 708.0
TH1_k127_5010778_3 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 591.0
TH1_k127_5010778_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 582.0
TH1_k127_5010778_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 567.0
TH1_k127_5010778_6 aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 544.0
TH1_k127_5010778_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 432.0
TH1_k127_5010778_8 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 318.0
TH1_k127_5010778_9 FAD binding domain K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 312.0
TH1_k127_5010878_0 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 493.0
TH1_k127_5010878_1 response regulator K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001073 265.0
TH1_k127_5010878_2 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000004058 108.0
TH1_k127_50155_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 7.737e-210 663.0
TH1_k127_50155_1 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 531.0
TH1_k127_50155_2 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 304.0
TH1_k127_50155_3 phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.0000000000000000000000000000000000000000000000000000000453 201.0
TH1_k127_50155_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000001519 77.0
TH1_k127_50155_5 - - - - 0.0002776 49.0
TH1_k127_5017800_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1613.0
TH1_k127_5017800_1 4Fe-4S dicluster domain - - - 1.007e-229 731.0
TH1_k127_5017800_10 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000006599 156.0
TH1_k127_5017800_11 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000001947 140.0
TH1_k127_5017800_12 Protein of unknown function (DUF3305) - - - 0.000000000000000000000000000001473 139.0
TH1_k127_5017800_13 Protein of unknown function (DUF3306) - - - 0.000000000000000000000000001024 123.0
TH1_k127_5017800_14 - - - - 0.000000000000000006061 88.0
TH1_k127_5017800_15 - - - - 0.00009176 48.0
TH1_k127_5017800_2 Chromate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 625.0
TH1_k127_5017800_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 514.0
TH1_k127_5017800_4 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 478.0
TH1_k127_5017800_5 4Fe-4S ferredoxin, iron-sulfur binding K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 409.0
TH1_k127_5017800_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 390.0
TH1_k127_5017800_7 formate dehydrogenase K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 320.0
TH1_k127_5017800_8 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 308.0
TH1_k127_5017800_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000155 265.0
TH1_k127_5038473_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 513.0
TH1_k127_5038473_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.00000000000000000000000000000000000000000000000000000001526 203.0
TH1_k127_5052618_0 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 406.0
TH1_k127_5052618_1 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001697 277.0
TH1_k127_5052618_2 LysE type translocator K05834 - - 0.00000000000000000000000000000000000000000000000000000000000000000001012 244.0
TH1_k127_5059539_0 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 8.945e-319 992.0
TH1_k127_5059539_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 7.278e-294 923.0
TH1_k127_5059539_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000005641 156.0
TH1_k127_5059539_2 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 3.755e-228 715.0
TH1_k127_5059539_3 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 587.0
TH1_k127_5059539_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 574.0
TH1_k127_5059539_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 513.0
TH1_k127_5059539_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 455.0
TH1_k127_5059539_7 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 360.0
TH1_k127_5059539_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005152 292.0
TH1_k127_5059539_9 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000003639 231.0
TH1_k127_5063125_0 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 516.0
TH1_k127_5077032_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 3.53e-231 741.0
TH1_k127_5077032_1 sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 500.0
TH1_k127_5077032_2 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 468.0
TH1_k127_5077032_3 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 353.0
TH1_k127_5077032_4 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000005583 252.0
TH1_k127_5077032_5 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000236 207.0
TH1_k127_5090164_0 VanZ like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 621.0
TH1_k127_5090164_1 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 467.0
TH1_k127_5090164_10 - - - - 0.0000000000000000000000005106 111.0
TH1_k127_5090164_11 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000004351 71.0
TH1_k127_5090164_2 Arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 453.0
TH1_k127_5090164_3 PFAM ABC transporter K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 411.0
TH1_k127_5090164_4 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 340.0
TH1_k127_5090164_5 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002901 284.0
TH1_k127_5090164_6 Molybdenum ABC transporter K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005616 271.0
TH1_k127_5090164_7 TIGRFAM decaheme c-type cytochrome, DmsE family - - - 0.00000000000000000000000000000000000000000000000000000000000000003206 236.0
TH1_k127_5090164_8 Flavodoxin-like fold K00355,K11748 - 1.6.5.2 0.00000000000000000000000000000000000000000000002096 177.0
TH1_k127_5090164_9 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000000007733 143.0
TH1_k127_5096359_0 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 435.0
TH1_k127_5096359_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000004604 156.0
TH1_k127_5100240_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 5.152e-296 916.0
TH1_k127_5100240_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 354.0
TH1_k127_5100240_2 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000007185 269.0
TH1_k127_5101978_0 PUA-like domain K00958 - 2.7.7.4 1.452e-220 689.0
TH1_k127_5101978_1 PFAM DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000161 263.0
TH1_k127_5119283_0 CoA binding domain - - - 0.0 1155.0
TH1_k127_5119283_1 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 1.831e-249 772.0
TH1_k127_5119283_2 Belongs to the TPP enzyme family K01577 - 4.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 518.0
TH1_k127_5119283_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.00000000000000000000000000000000000000000000001779 175.0
TH1_k127_5127154_0 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 362.0
TH1_k127_5127154_1 epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 329.0
TH1_k127_5127154_2 glycosylase K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000001689 184.0
TH1_k127_5127154_3 Dienelactone hydrolase family - - - 0.00000004448 58.0
TH1_k127_5135200_0 COG0183 Acetyl-CoA acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 584.0
TH1_k127_5135200_1 COG1960 Acyl-CoA dehydrogenases K18244 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 567.0
TH1_k127_5135200_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 359.0
TH1_k127_5135200_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 330.0
TH1_k127_5135200_4 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001477 298.0
TH1_k127_5135200_5 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000005676 176.0
TH1_k127_514243_0 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 475.0
TH1_k127_514243_1 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 356.0
TH1_k127_514243_2 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 297.0
TH1_k127_514243_3 Psort location Cytoplasmic, score 8.96 K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000004357 226.0
TH1_k127_514243_4 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000495 103.0
TH1_k127_514243_5 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000004315 81.0
TH1_k127_514243_6 - - - - 0.0000000002215 70.0
TH1_k127_5165027_0 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 329.0
TH1_k127_5165027_1 TPM domain - - - 0.00000000000131 71.0
TH1_k127_5170368_0 Belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 3.001e-213 675.0
TH1_k127_5170368_1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 385.0
TH1_k127_5170368_2 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001897 249.0
TH1_k127_5170368_3 Protein of unknown function (DUF2505) - - - 0.00000000000000000000000000000157 127.0
TH1_k127_5170368_4 SnoaL-like domain - - - 0.00000000004218 69.0
TH1_k127_5174741_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 377.0
TH1_k127_5174741_1 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 347.0
TH1_k127_5174741_2 Bacterial pre-peptidase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000002558 199.0
TH1_k127_5174741_3 COG3639 ABC-type phosphate phosphonate transport system, permease component - - - 0.0000000000000000000000000000000000002411 156.0
TH1_k127_5195525_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1022.0
TH1_k127_5195525_1 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 587.0
TH1_k127_5195525_10 - - - - 0.0000000000000000000000000000002232 128.0
TH1_k127_5195525_11 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000001593 104.0
TH1_k127_5195525_2 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 490.0
TH1_k127_5195525_3 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 361.0
TH1_k127_5195525_4 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 345.0
TH1_k127_5195525_5 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 335.0
TH1_k127_5195525_6 Fe-S oxidoreductase K21834 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 301.0
TH1_k127_5195525_7 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000188 289.0
TH1_k127_5195525_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000229 235.0
TH1_k127_5195525_9 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000000000000000000000000009282 167.0
TH1_k127_5196975_0 radical SAM domain protein - - - 3.723e-219 693.0
TH1_k127_5196975_1 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001147 280.0
TH1_k127_5196975_2 ribonuclease activity - - - 0.00000000000000000000000000000000000000000000009315 171.0
TH1_k127_5196975_3 SpoVT AbrB like domain - - - 0.00000000006702 68.0
TH1_k127_5201970_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 9.158e-217 681.0
TH1_k127_5201970_1 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 555.0
TH1_k127_5201970_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000004505 91.0
TH1_k127_5203721_0 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000009656 231.0
TH1_k127_5203721_1 Beta/gamma crystallins - - - 0.000000000000000000000000000000000000000000001211 178.0
TH1_k127_5203721_2 transcriptional regulator, AraC family - - - 0.000000000000001782 87.0
TH1_k127_522448_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1196.0
TH1_k127_522448_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1101.0
TH1_k127_522448_10 Two component regulator three Y domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 411.0
TH1_k127_522448_11 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000006262 280.0
TH1_k127_522448_12 UPF0114 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001709 259.0
TH1_k127_522448_13 MobA-Related Protein K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000001566 181.0
TH1_k127_522448_14 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000003869 160.0
TH1_k127_522448_15 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000009275 149.0
TH1_k127_522448_16 Domain of unknown function (DUF4212) - - - 0.0000000000000000000000000000007812 123.0
TH1_k127_522448_17 - - - - 0.00000000000000006696 85.0
TH1_k127_522448_18 - - - - 0.00000000000000006784 86.0
TH1_k127_522448_19 - - - - 0.00000000000002202 76.0
TH1_k127_522448_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 2.494e-286 894.0
TH1_k127_522448_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.558e-275 855.0
TH1_k127_522448_4 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 624.0
TH1_k127_522448_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 588.0
TH1_k127_522448_6 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 531.0
TH1_k127_522448_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 526.0
TH1_k127_522448_8 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 430.0
TH1_k127_522448_9 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 421.0
TH1_k127_522770_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1545.0
TH1_k127_522770_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1047.0
TH1_k127_522770_10 PFAM Response regulator receiver domain K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 290.0
TH1_k127_522770_11 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000389 249.0
TH1_k127_522770_12 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000001315 233.0
TH1_k127_522770_13 Ferredoxin K05337 - - 0.000000000000000000000000001891 127.0
TH1_k127_522770_2 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 3.103e-279 882.0
TH1_k127_522770_3 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 602.0
TH1_k127_522770_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 411.0
TH1_k127_522770_5 PFAM ATP-binding region ATPase domain protein K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 392.0
TH1_k127_522770_6 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 373.0
TH1_k127_522770_7 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 384.0
TH1_k127_522770_8 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 357.0
TH1_k127_522770_9 fumarate reductase respiratory complex transmembrane subunit K00246 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 336.0
TH1_k127_5236867_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000238 297.0
TH1_k127_5237274_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 455.0
TH1_k127_5237274_1 ABC-2 family transporter protein K09696 - - 0.0000000000000000000000000000000005669 138.0
TH1_k127_5258087_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 3.194e-197 617.0
TH1_k127_5258087_1 MauM NapG family ferredoxin-type protein K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 343.0
TH1_k127_5258087_2 4Fe-4S binding domain K02574 - - 0.00000000000000000000000000000000000000000000000000006869 191.0
TH1_k127_5290486_0 TldD PmbA family protein K03568 - - 3.87e-222 698.0
TH1_k127_5290486_1 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 2.011e-219 691.0
TH1_k127_5290486_2 abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 309.0
TH1_k127_5292_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1318.0
TH1_k127_5292_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 5.302e-213 680.0
TH1_k127_5292_10 Mur ligase middle domain K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 432.0
TH1_k127_5292_11 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 412.0
TH1_k127_5292_12 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 411.0
TH1_k127_5292_13 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 372.0
TH1_k127_5292_14 General function prediction only K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 371.0
TH1_k127_5292_15 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 376.0
TH1_k127_5292_16 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 354.0
TH1_k127_5292_17 surface antigen K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 357.0
TH1_k127_5292_18 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 353.0
TH1_k127_5292_19 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 324.0
TH1_k127_5292_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 8.802e-209 663.0
TH1_k127_5292_20 Peptidase family M23 K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 314.0
TH1_k127_5292_21 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 302.0
TH1_k127_5292_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003836 249.0
TH1_k127_5292_23 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000004548 234.0
TH1_k127_5292_24 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000002024 229.0
TH1_k127_5292_25 Type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000002124 223.0
TH1_k127_5292_26 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000002385 210.0
TH1_k127_5292_27 protein conserved in bacteria K09800 - - 0.000000000000000000000000000000000000000000000000000002355 216.0
TH1_k127_5292_28 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000003349 195.0
TH1_k127_5292_29 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000008526 143.0
TH1_k127_5292_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.424e-196 629.0
TH1_k127_5292_30 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000000158 100.0
TH1_k127_5292_31 - - - - 0.0000000000004866 77.0
TH1_k127_5292_32 Protein of unknown function (DUF721) - - - 0.00000003441 62.0
TH1_k127_5292_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 590.0
TH1_k127_5292_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 516.0
TH1_k127_5292_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 486.0
TH1_k127_5292_7 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 460.0
TH1_k127_5292_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 448.0
TH1_k127_5292_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 433.0
TH1_k127_5295306_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 539.0
TH1_k127_5295306_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 440.0
TH1_k127_5295306_2 Cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000003151 230.0
TH1_k127_5295306_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000001994 190.0
TH1_k127_5295306_4 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000003207 164.0
TH1_k127_5295306_5 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000258 64.0
TH1_k127_530414_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.49e-252 789.0
TH1_k127_530414_1 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 499.0
TH1_k127_530414_10 Protein of unknown function (DUF3095) - - - 0.000004406 51.0
TH1_k127_530414_11 Transposase domain (DUF772) - - - 0.00001962 50.0
TH1_k127_530414_12 KR domain - - - 0.000147 55.0
TH1_k127_530414_13 Protein of unknown function (DUF3095) - - - 0.0005322 49.0
TH1_k127_530414_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 439.0
TH1_k127_530414_3 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 413.0
TH1_k127_530414_4 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 336.0
TH1_k127_530414_5 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003497 251.0
TH1_k127_530414_6 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000004265 238.0
TH1_k127_530414_7 restriction endonuclease K07448 - - 0.000000000000000000000000000000000000000000000008171 179.0
TH1_k127_530414_8 Protein of unknown function (DUF3095) - - - 0.00000000000000000000000000005071 123.0
TH1_k127_530414_9 - - - - 0.0000002817 62.0
TH1_k127_5332415_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.621e-298 920.0
TH1_k127_5332415_1 PFAM Type II secretion system protein E K02454 - - 5.217e-210 668.0
TH1_k127_5332415_10 SURF1 family - - - 0.0000000000000000000000000000000000000000000000003764 184.0
TH1_k127_5332415_11 signal sequence binding - - - 0.0000000000000000000000000000000483 141.0
TH1_k127_5332415_12 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000009528 124.0
TH1_k127_5332415_13 Rubredoxin - - - 0.0000000000000000000000000002768 114.0
TH1_k127_5332415_14 Protein of unknown function (DUF2909) - - - 0.0000006151 61.0
TH1_k127_5332415_15 General secretion pathway protein K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.00007062 45.0
TH1_k127_5332415_2 Aminotransferase K01845 - 5.4.3.8 7.468e-197 625.0
TH1_k127_5332415_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 499.0
TH1_k127_5332415_4 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 406.0
TH1_k127_5332415_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 410.0
TH1_k127_5332415_6 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 392.0
TH1_k127_5332415_7 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004381 268.0
TH1_k127_5332415_8 oxidase assembly K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000000002674 242.0
TH1_k127_5332415_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000003464 202.0
TH1_k127_5346053_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 7.525e-227 718.0
TH1_k127_5346053_1 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 587.0
TH1_k127_5383926_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.522e-201 634.0
TH1_k127_5383926_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 3.563e-197 622.0
TH1_k127_5383926_10 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000007555 141.0
TH1_k127_5383926_11 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000000103 116.0
TH1_k127_5383926_12 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000001697 81.0
TH1_k127_5383926_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 435.0
TH1_k127_5383926_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 405.0
TH1_k127_5383926_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 381.0
TH1_k127_5383926_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 373.0
TH1_k127_5383926_6 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 338.0
TH1_k127_5383926_7 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000005963 255.0
TH1_k127_5383926_8 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000004321 226.0
TH1_k127_5383926_9 CBS domain - - - 0.000000000000000000000000000000000000000000002426 170.0
TH1_k127_5405759_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.69e-197 627.0
TH1_k127_5405759_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 437.0
TH1_k127_5405759_2 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 409.0
TH1_k127_5405759_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 304.0
TH1_k127_5405759_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006887 252.0
TH1_k127_5405759_5 Protein of unknown function (DUF1778) - - - 0.0000000000000000000000000000000000000000002092 160.0
TH1_k127_543024_0 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 2.686e-248 771.0
TH1_k127_543024_1 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 575.0
TH1_k127_543024_10 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001405 259.0
TH1_k127_543024_11 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000000000000000000000001362 212.0
TH1_k127_543024_12 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000000000000000000002764 200.0
TH1_k127_543024_13 - - - - 0.000000000000000000000000000000000000000000000003457 181.0
TH1_k127_543024_14 redox protein, regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000001668 161.0
TH1_k127_543024_15 DsrC like protein K11179 - - 0.000000000000000000000000000000000000006345 147.0
TH1_k127_543024_16 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000008587 123.0
TH1_k127_543024_17 Peptidase S24-like - - - 0.000000000000000000000000000001699 124.0
TH1_k127_543024_18 Cas6 Crispr - - - 0.000000000000000000000000000008599 128.0
TH1_k127_543024_19 - - - - 0.0000000000000000004593 89.0
TH1_k127_543024_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 547.0
TH1_k127_543024_20 - - - - 0.0000000000000000009024 91.0
TH1_k127_543024_21 - - - - 0.000000009632 63.0
TH1_k127_543024_3 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 557.0
TH1_k127_543024_4 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 476.0
TH1_k127_543024_5 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 458.0
TH1_k127_543024_6 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 418.0
TH1_k127_543024_7 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 350.0
TH1_k127_543024_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 324.0
TH1_k127_543024_9 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000001463 257.0
TH1_k127_54420_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.958e-237 746.0
TH1_k127_54420_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 561.0
TH1_k127_54420_2 Mediates influx of magnesium ions K03284,K16074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008628 260.0
TH1_k127_5497162_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.336e-201 653.0
TH1_k127_5497162_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 528.0
TH1_k127_5497162_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 358.0
TH1_k127_5497162_3 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 340.0
TH1_k127_5497162_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 289.0
TH1_k127_5497162_5 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006456 276.0
TH1_k127_5497162_6 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000003465 210.0
TH1_k127_5497162_7 ApaG domain - - - 0.000000000000000000000000000000000000000000000000003759 196.0
TH1_k127_550437_0 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 4.928e-234 737.0
TH1_k127_550437_1 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 559.0
TH1_k127_550437_2 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 547.0
TH1_k127_550437_3 TIR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 353.0
TH1_k127_550437_4 WD40 repeat, subgroup - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 319.0
TH1_k127_550437_5 Protein of unknown function (DUF2783) - - - 0.000000000000000004745 89.0
TH1_k127_550437_6 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.00000000001033 78.0
TH1_k127_5517658_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1231.0
TH1_k127_5517658_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly - - - 5.701e-266 834.0
TH1_k127_5517658_2 Belongs to the thiolase family - - - 1.708e-199 628.0
TH1_k127_5517658_3 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 585.0
TH1_k127_5517658_4 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 493.0
TH1_k127_5517658_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 345.0
TH1_k127_5517658_6 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000000000000000001199 224.0
TH1_k127_5517658_7 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS-like protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000002039 186.0
TH1_k127_5517658_8 III protein, CoA-transferase family - - - 0.00000000000009479 77.0
TH1_k127_5517658_9 GntR family - - - 0.000000001582 59.0
TH1_k127_5570793_0 COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B K13482 - 1.17.1.4 0.0 1161.0
TH1_k127_5570793_1 (ABC) transporter K02056 - 3.6.3.17 1.151e-254 794.0
TH1_k127_5570793_10 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 481.0
TH1_k127_5570793_11 Peptidase dimerisation domain K02083 - 3.5.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 406.0
TH1_k127_5570793_12 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 320.0
TH1_k127_5570793_13 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005499 276.0
TH1_k127_5570793_14 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000988 253.0
TH1_k127_5570793_15 periplasmic protein - - - 0.00000000000000000000000000000000000000000000000000000008982 205.0
TH1_k127_5570793_16 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000008005 197.0
TH1_k127_5570793_17 - - - - 0.000000000000000000000000000000000000000008858 173.0
TH1_k127_5570793_18 CbiX K03795 - 4.99.1.3 0.0000000000000000000000004477 118.0
TH1_k127_5570793_19 Predicted membrane protein (DUF2069) - - - 0.0000000000000000001185 93.0
TH1_k127_5570793_2 Belongs to the pyruvate kinase family - - - 5.167e-202 638.0
TH1_k127_5570793_3 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 3.795e-199 634.0
TH1_k127_5570793_4 COG0402 Cytosine deaminase and related metal-dependent hydrolases K01487 - 3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 588.0
TH1_k127_5570793_5 Pfam:DUF989 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 577.0
TH1_k127_5570793_6 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 556.0
TH1_k127_5570793_7 chitin deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 541.0
TH1_k127_5570793_8 Basic membrane lipoprotein K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 535.0
TH1_k127_5570793_9 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 533.0
TH1_k127_5583265_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.196e-260 820.0
TH1_k127_5583265_1 thiamine transport K02011 - - 2.172e-229 722.0
TH1_k127_5583265_10 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000009458 192.0
TH1_k127_5583265_11 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000002171 128.0
TH1_k127_5583265_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 543.0
TH1_k127_5583265_3 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 507.0
TH1_k127_5583265_4 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 462.0
TH1_k127_5583265_5 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 468.0
TH1_k127_5583265_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 463.0
TH1_k127_5583265_7 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 401.0
TH1_k127_5583265_8 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 370.0
TH1_k127_5583265_9 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 342.0
TH1_k127_5619834_0 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 298.0
TH1_k127_5619834_1 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.00000000000000000000000000000000000000002644 165.0
TH1_k127_5619834_2 Caudovirus prohead serine protease K06904 - - 0.0000000000000000000000000000000000000000382 160.0
TH1_k127_565603_0 type IV-A pilus assembly ATPase PilB K02652 - - 8.126e-252 790.0
TH1_k127_565603_1 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 2.796e-194 613.0
TH1_k127_565603_10 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000001513 212.0
TH1_k127_565603_11 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000007224 201.0
TH1_k127_565603_12 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000002475 192.0
TH1_k127_565603_13 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000000000000004147 182.0
TH1_k127_565603_14 Hemerythrin HHE cation binding - - - 0.0000000000000000000000000000000000000000000009862 175.0
TH1_k127_565603_15 periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000000000002447 174.0
TH1_k127_565603_16 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000001285 163.0
TH1_k127_565603_17 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000211 156.0
TH1_k127_565603_18 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000001306 129.0
TH1_k127_565603_19 Invasion gene expression up-regulator SirB - - - 0.0000000000000000000000000000009971 130.0
TH1_k127_565603_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 612.0
TH1_k127_565603_20 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000006955 119.0
TH1_k127_565603_21 RDD family - - - 0.000001202 62.0
TH1_k127_565603_22 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000001202 62.0
TH1_k127_565603_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 590.0
TH1_k127_565603_4 Domain of unknown function DUF21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 463.0
TH1_k127_565603_5 Benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 445.0
TH1_k127_565603_6 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 379.0
TH1_k127_565603_7 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 322.0
TH1_k127_565603_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000001449 275.0
TH1_k127_565603_9 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000002029 260.0
TH1_k127_566366_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 361.0
TH1_k127_566366_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000002087 233.0
TH1_k127_5671845_0 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 539.0
TH1_k127_5671845_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 400.0
TH1_k127_5671845_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000005087 145.0
TH1_k127_571618_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.211e-290 911.0
TH1_k127_571618_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 487.0
TH1_k127_571618_10 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002438 252.0
TH1_k127_571618_11 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000001344 243.0
TH1_k127_571618_12 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000006162 228.0
TH1_k127_571618_13 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000008749 224.0
TH1_k127_571618_14 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000001246 225.0
TH1_k127_571618_15 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000000000000000002936 191.0
TH1_k127_571618_16 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000001776 91.0
TH1_k127_571618_17 Fels-1 Prophage Protein-like - - - 0.0000000000000001301 83.0
TH1_k127_571618_2 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 436.0
TH1_k127_571618_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 392.0
TH1_k127_571618_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 366.0
TH1_k127_571618_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 367.0
TH1_k127_571618_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 334.0
TH1_k127_571618_7 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 327.0
TH1_k127_571618_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 282.0
TH1_k127_571618_9 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001569 282.0
TH1_k127_5737538_0 mandelate racemase muconate lactonizing K01706 - 4.2.1.40 2.91e-199 628.0
TH1_k127_5737538_1 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 430.0
TH1_k127_5737538_2 Regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000001953 242.0
TH1_k127_5737538_3 PFAM Short-chain dehydrogenase reductase SDR K18335 - - 0.0000000000000000000000000000000000000000000004266 171.0
TH1_k127_58535_0 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 3.586e-211 671.0
TH1_k127_58535_1 Arsenical pump membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 586.0
TH1_k127_58535_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 375.0
TH1_k127_58535_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000006678 246.0
TH1_k127_58535_4 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000003111 241.0
TH1_k127_58535_5 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000004198 164.0
TH1_k127_58535_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000001086 130.0
TH1_k127_58535_7 Membrane transport protein K07088 - - 0.0000000000000000000000003577 107.0
TH1_k127_58535_8 Dodecin K09165 - - 0.0000000000000000000003744 102.0
TH1_k127_5964601_0 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 392.0
TH1_k127_5964601_1 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 340.0
TH1_k127_5964601_2 Bacterial-like globin K06886 - - 0.0000000000392 66.0
TH1_k127_6085563_0 NADH:flavin oxidoreductase / NADH oxidase family K00219,K09461 - 1.14.13.40,1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 381.0
TH1_k127_6085563_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 366.0
TH1_k127_6085563_2 PFAM Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000003164 108.0
TH1_k127_6086220_0 Carbohydrate phosphorylase K00688 GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 5.978e-214 677.0
TH1_k127_6086220_1 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 439.0
TH1_k127_6086220_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000006704 158.0
TH1_k127_6086220_3 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0000000000000000001603 87.0
TH1_k127_6101500_0 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 576.0
TH1_k127_6101500_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 535.0
TH1_k127_6101500_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000001216 138.0
TH1_k127_6120948_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 6.895e-276 853.0
TH1_k127_6120948_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.033e-257 805.0
TH1_k127_6120948_10 subunit II K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 336.0
TH1_k127_6120948_11 PFAM type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 341.0
TH1_k127_6120948_12 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 336.0
TH1_k127_6120948_13 Transcriptional regulator crp fnr family K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 303.0
TH1_k127_6120948_14 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 292.0
TH1_k127_6120948_15 PFAM 20S proteasome, A and B subunits K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000003583 250.0
TH1_k127_6120948_16 PFAM Lytic transglycosylase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000006926 228.0
TH1_k127_6120948_17 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000394 205.0
TH1_k127_6120948_18 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000002049 206.0
TH1_k127_6120948_19 transcriptional regulator K07734 - - 0.000000000000000000000000000000000000000000004906 171.0
TH1_k127_6120948_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 5.196e-233 734.0
TH1_k127_6120948_20 atpase or kinase K06925 - - 0.00000000000000000000000000000000000000000001184 171.0
TH1_k127_6120948_21 PFAM regulatory protein, MerR K22491 - - 0.00000000000000000000000000000000000000000002126 177.0
TH1_k127_6120948_22 Universal stress protein - - - 0.0000000000000000000000000000000000002579 149.0
TH1_k127_6120948_23 FixH family K09926 - - 0.000000000000000000000000000002577 132.0
TH1_k127_6120948_24 - - - - 0.00000000000000000000000000004685 134.0
TH1_k127_6120948_25 - - - - 0.000000000000000000000000008941 123.0
TH1_k127_6120948_26 - - - - 0.00000000000000000000000003794 116.0
TH1_k127_6120948_27 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000002692 75.0
TH1_k127_6120948_28 Cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000003406 78.0
TH1_k127_6120948_29 Cbb3-type cytochrome oxidase subunit K00407 - - 0.00001304 49.0
TH1_k127_6120948_3 cation transport ATPase K01533 - 3.6.3.4 3.556e-207 676.0
TH1_k127_6120948_30 Psort location CytoplasmicMembrane, score - - - 0.0002336 53.0
TH1_k127_6120948_4 general secretion pathway protein D K02453 - - 6.368e-196 635.0
TH1_k127_6120948_5 cytochrome C oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 610.0
TH1_k127_6120948_6 type II secretion system protein E K02454,K02652,K12276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 592.0
TH1_k127_6120948_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 500.0
TH1_k127_6120948_8 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 452.0
TH1_k127_6120948_9 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 370.0
TH1_k127_6132762_0 Sulfatase K01130 - 3.1.6.1 0.0 1514.0
TH1_k127_6132762_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 6.365e-266 851.0
TH1_k127_6132762_10 ABC-type transport auxiliary lipoprotein component - - - 0.00000000000000000000000000000000000000000000000000000000001646 212.0
TH1_k127_6132762_11 - - - - 0.000000000000000000000000000000000000000000000000000004799 200.0
TH1_k127_6132762_2 Protein tyrosine kinase K12132 - 2.7.11.1 1.18e-219 713.0
TH1_k127_6132762_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.744e-218 701.0
TH1_k127_6132762_4 PFAM Mammalian cell entry related K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 610.0
TH1_k127_6132762_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 347.0
TH1_k127_6132762_6 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002935 282.0
TH1_k127_6132762_7 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001356 290.0
TH1_k127_6132762_8 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000003355 253.0
TH1_k127_6132762_9 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000000003342 229.0
TH1_k127_6137315_0 FAD linked oxidase - - - 0.0 1507.0
TH1_k127_6137315_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1388.0
TH1_k127_6137315_2 Protein of unknown function, DUF255 - - - 4.247e-238 758.0
TH1_k127_6137315_3 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 520.0
TH1_k127_6137315_4 Oxidative deamination of D-amino acids K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 512.0
TH1_k127_6137315_5 - - - - 0.0000000000000000000000000000000000000000000000000006124 205.0
TH1_k127_6137315_6 Histidine triad (HIT) protein - - - 0.00000000000000000000000000000000000000000002713 165.0
TH1_k127_6137315_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.00000000000000000000000000000000000000000003924 168.0
TH1_k127_6137315_8 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000304 61.0
TH1_k127_6137825_0 Sulfatase - - - 0.0 1001.0
TH1_k127_6137825_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.576e-218 700.0
TH1_k127_6137825_10 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003388 278.0
TH1_k127_6137825_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001491 239.0
TH1_k127_6137825_12 regulatory protein LysR - - - 0.000000000000000000000000000000000000000000000000000000002757 213.0
TH1_k127_6137825_13 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000004322 202.0
TH1_k127_6137825_14 Shikimate kinase K00851 - 2.7.1.12 0.000000000000000000000000000000000000000000003517 170.0
TH1_k127_6137825_15 - - - - 0.00000000000000000000000000000000000000000004952 170.0
TH1_k127_6137825_16 Bacterial extracellular solute-binding protein - - - 0.0001697 46.0
TH1_k127_6137825_2 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 604.0
TH1_k127_6137825_3 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 495.0
TH1_k127_6137825_4 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 443.0
TH1_k127_6137825_5 Bacterial extracellular solute-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 425.0
TH1_k127_6137825_6 ABC transporter K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 314.0
TH1_k127_6137825_7 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 298.0
TH1_k127_6137825_8 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 306.0
TH1_k127_6137825_9 Peptidase C26 K01658,K07010 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 296.0
TH1_k127_6145914_0 ATP-independent chaperone mediated protein folding K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 514.0
TH1_k127_6145914_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007203 431.0
TH1_k127_6145914_10 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000005919 169.0
TH1_k127_6145914_11 Phasin protein - - - 0.000000000000000000000000000001113 131.0
TH1_k127_6145914_12 S-layer homology domain - - - 0.00000000007715 75.0
TH1_k127_6145914_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 411.0
TH1_k127_6145914_3 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 380.0
TH1_k127_6145914_4 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 306.0
TH1_k127_6145914_5 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 299.0
TH1_k127_6145914_6 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001006 293.0
TH1_k127_6145914_7 Aldose 1-epimerase K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000177 289.0
TH1_k127_6145914_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003124 264.0
TH1_k127_6145914_9 synthesis repressor, PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000007439 239.0
TH1_k127_6155941_0 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 291.0
TH1_k127_6155941_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008334 232.0
TH1_k127_6155941_2 nucleic acid-binding protein contains PIN domain K07062 - - 0.00000000000000000000000000000000000000000000000000113 187.0
TH1_k127_6155941_3 conserved protein, contains double-stranded beta-helix domain - - - 0.00000000000000000000000000000001001 130.0
TH1_k127_6155941_4 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000002137 87.0
TH1_k127_6155941_5 Plasmid stability protein - - - 0.000000000000003509 83.0
TH1_k127_6155941_6 Putative addiction module component - - - 0.00000000000002277 80.0
TH1_k127_6161691_0 GcpE protein K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 612.0
TH1_k127_6161691_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 579.0
TH1_k127_6161691_10 type 4 pilus biogenesis protein K02656 - - 0.000000000000000000000000000000000000000000000000000003431 200.0
TH1_k127_6161691_11 Helix-turn-helix domain K15539 - - 0.0000000000000000000000000000000000000000006629 168.0
TH1_k127_6161691_12 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000002916 141.0
TH1_k127_6161691_13 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000004484 129.0
TH1_k127_6161691_14 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000001959 78.0
TH1_k127_6161691_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 521.0
TH1_k127_6161691_3 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 494.0
TH1_k127_6161691_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 443.0
TH1_k127_6161691_5 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 370.0
TH1_k127_6161691_6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 367.0
TH1_k127_6161691_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 357.0
TH1_k127_6161691_8 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000002458 245.0
TH1_k127_6161691_9 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000001761 205.0
TH1_k127_616678_0 Participates in both transcription termination and antitermination K02600 - - 1.8e-220 700.0
TH1_k127_616678_1 Bacterial protein of unknown function (DUF853) K06915 - - 1.137e-208 661.0
TH1_k127_616678_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 503.0
TH1_k127_616678_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000002221 169.0
TH1_k127_6170998_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 5.431e-204 661.0
TH1_k127_6170998_1 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 597.0
TH1_k127_6170998_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 578.0
TH1_k127_6170998_3 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 515.0
TH1_k127_6170998_4 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 309.0
TH1_k127_6170998_5 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.0001061 55.0
TH1_k127_61746_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.719e-310 969.0
TH1_k127_61746_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 608.0
TH1_k127_61746_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 341.0
TH1_k127_61746_3 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000000003717 201.0
TH1_k127_61746_4 Sulphur oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000000000000001337 163.0
TH1_k127_61746_5 intradiol ring-cleavage dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000002976 159.0
TH1_k127_61746_6 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine - - - 0.000000000000000000000000000001562 126.0
TH1_k127_61746_7 Belongs to the phosphoglycerate kinase family K00927 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 0.0000000000000001782 81.0
TH1_k127_61746_8 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000002108 79.0
TH1_k127_6175857_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 2.891e-225 709.0
TH1_k127_6175857_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 3.62e-202 634.0
TH1_k127_6175857_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 513.0
TH1_k127_6175857_3 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 461.0
TH1_k127_6175857_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 342.0
TH1_k127_6175857_5 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000002805 241.0
TH1_k127_6175857_6 ABC-type sugar transport system, periplasmic component K05813 - - 0.000000000000000000000000000000006798 132.0
TH1_k127_6196142_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 477.0
TH1_k127_6196142_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 448.0
TH1_k127_6196142_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001873 276.0
TH1_k127_6196142_3 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003257 277.0
TH1_k127_6196142_4 Enoyl-CoA hydratase/isomerase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007327 280.0
TH1_k127_6196142_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004507 267.0
TH1_k127_6196142_6 META domain K03929 - - 0.00000000000000000001045 98.0
TH1_k127_6221635_0 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 350.0
TH1_k127_6221635_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 328.0
TH1_k127_6245637_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 546.0
TH1_k127_6245637_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000003892 196.0
TH1_k127_6245637_2 transcription factor binding K02584,K07713 - - 0.000000000000000000002016 103.0
TH1_k127_6294766_0 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 548.0
TH1_k127_6294766_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 527.0
TH1_k127_6294766_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 524.0
TH1_k127_6294766_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 531.0
TH1_k127_6294766_4 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 505.0
TH1_k127_6294766_5 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 331.0
TH1_k127_6294766_6 hydrolases of the HAD superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 335.0
TH1_k127_6294766_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000002434 186.0
TH1_k127_6302510_0 Protein of unknown function (DUF3604) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 303.0
TH1_k127_6302510_1 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008093 239.0
TH1_k127_6302510_2 Transglycosylase associated protein - - - 0.0000000000000000000000000000000000006632 141.0
TH1_k127_6302510_4 HupE / UreJ protein - - - 0.0000000001685 66.0
TH1_k127_6317607_0 Belongs to the enoyl-CoA hydratase isomerase family K19640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 571.0
TH1_k127_6317607_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000006841 153.0
TH1_k127_6317607_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000003138 98.0
TH1_k127_6317607_3 PFAM cytochrome c, class I K08738 - - 0.0000000000003333 74.0
TH1_k127_6317607_4 Cytochrome c K08738 - - 0.000000000002524 70.0
TH1_k127_6323546_0 ABC transporter transmembrane region K06147 - - 1.572e-264 831.0
TH1_k127_6323546_1 DNA polymerase X family K02347 - - 2.906e-234 734.0
TH1_k127_6323546_10 DsrE/DsrF-like family K06039 - - 0.0000000000000000000000000000000000000000000001401 171.0
TH1_k127_6323546_2 oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 456.0
TH1_k127_6323546_3 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 421.0
TH1_k127_6323546_4 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 373.0
TH1_k127_6323546_5 PFAM Endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 307.0
TH1_k127_6323546_6 transcriptional regulator, ArsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008288 277.0
TH1_k127_6323546_7 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009492 279.0
TH1_k127_6323546_8 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000417 245.0
TH1_k127_6323546_9 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000001179 241.0
TH1_k127_6349401_0 Histidine kinase-like ATPases - - - 1.244e-234 782.0
TH1_k127_6349401_1 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 574.0
TH1_k127_6349401_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 432.0
TH1_k127_6349401_3 Histidine kinase K20976 - - 0.0000000000000000000005809 101.0
TH1_k127_6349401_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000002704 88.0
TH1_k127_6353512_0 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001626 248.0
TH1_k127_6353512_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000001935 222.0
TH1_k127_6354802_0 Cytochrome b(N-terminal)/b6/petB - - - 1.209e-236 751.0
TH1_k127_6354802_1 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 351.0
TH1_k127_6354802_2 - - - - 0.000000000000000000000000000000004107 133.0
TH1_k127_6354802_3 SCP-2 sterol transfer family - - - 0.0000000000000000000000000002708 119.0
TH1_k127_6354980_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.0 1645.0
TH1_k127_6354980_1 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 2.62e-242 761.0
TH1_k127_6354980_10 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 321.0
TH1_k127_6354980_11 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002443 248.0
TH1_k127_6354980_12 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000326 254.0
TH1_k127_6354980_13 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000002406 255.0
TH1_k127_6354980_14 ABC-type amino acid transport signal transduction systems periplasmic component domain K10001 GO:0003333,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015740,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016595,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070335,GO:0070778,GO:0071702,GO:0071705,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000003506 225.0
TH1_k127_6354980_15 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000006147 179.0
TH1_k127_6354980_17 Protein conserved in bacteria K18480 - - 0.0000000000000000007837 101.0
TH1_k127_6354980_18 Glycine zipper 2TM domain - - - 0.0000003407 59.0
TH1_k127_6354980_2 Phospholipase, patatin family K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 558.0
TH1_k127_6354980_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 550.0
TH1_k127_6354980_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 517.0
TH1_k127_6354980_5 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 488.0
TH1_k127_6354980_6 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 448.0
TH1_k127_6354980_7 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 368.0
TH1_k127_6354980_8 PFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 353.0
TH1_k127_6354980_9 COG3264 Small-conductance mechanosensitive channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 340.0
TH1_k127_63712_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 289.0
TH1_k127_63712_1 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000000000004089 219.0
TH1_k127_6373566_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 547.0
TH1_k127_6373566_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 472.0
TH1_k127_6373566_10 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.000000000000000000000000000000000000001729 150.0
TH1_k127_6373566_11 Pfam Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000000001992 150.0
TH1_k127_6373566_12 TonB C terminal K03646 - - 0.000000000000000000000000000000007097 138.0
TH1_k127_6373566_13 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000006431 132.0
TH1_k127_6373566_2 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 390.0
TH1_k127_6373566_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 383.0
TH1_k127_6373566_4 P-loop ATPase protein family K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 338.0
TH1_k127_6373566_5 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008998 286.0
TH1_k127_6373566_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002259 274.0
TH1_k127_6373566_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000001191 233.0
TH1_k127_6373566_8 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.00000000000000000000000000000000000000000000000000006434 192.0
TH1_k127_6373566_9 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000002192 167.0
TH1_k127_637522_0 twitching motility protein K02670 - - 2.535e-196 621.0
TH1_k127_637522_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 583.0
TH1_k127_637522_10 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005053 274.0
TH1_k127_637522_11 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000002371 255.0
TH1_k127_637522_12 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000000000003799 203.0
TH1_k127_637522_13 Tim44 - - - 0.00000000000000000000000000000000000000000000000002401 192.0
TH1_k127_637522_14 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000005361 167.0
TH1_k127_637522_15 branched-chain amino acid permease (azaleucine resistance) - - - 0.000000000000000000000000000000000000000005052 163.0
TH1_k127_637522_16 SCP-2 sterol transfer family K03690 - - 0.000000000000007529 82.0
TH1_k127_637522_2 Belongs to the glycosyl hydrolase 31 family K01811 GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0016787,GO:0016798,GO:0042802,GO:0080176 3.2.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 515.0
TH1_k127_637522_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 345.0
TH1_k127_637522_4 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 328.0
TH1_k127_637522_5 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 326.0
TH1_k127_637522_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 299.0
TH1_k127_637522_7 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 302.0
TH1_k127_637522_8 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 287.0
TH1_k127_637522_9 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004341 297.0
TH1_k127_6400087_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.191e-226 723.0
TH1_k127_6400087_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 6.947e-215 671.0
TH1_k127_6400087_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 3.828e-203 644.0
TH1_k127_6400087_3 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 575.0
TH1_k127_6400087_4 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 453.0
TH1_k127_6400087_5 ATP synthase subunit D K02120 - - 0.0000000000000000000000000000000000000000000005114 172.0
TH1_k127_6400087_6 - - - - 0.000000000000000000000000000000000000006517 158.0
TH1_k127_6400087_7 - - - - 0.0000000000000000000005831 104.0
TH1_k127_6400087_8 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.00000000000000000008996 105.0
TH1_k127_6400087_9 ATP synthase (F/14-kDa) subunit - - - 0.00000000007516 71.0
TH1_k127_6420252_0 Hsp90 protein K04079 - - 0.0 1027.0
TH1_k127_6420252_1 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009298 275.0
TH1_k127_6420252_2 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009746 261.0
TH1_k127_6420252_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000004418 68.0
TH1_k127_6420475_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 420.0
TH1_k127_6420475_1 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 401.0
TH1_k127_644091_0 Adenylate and Guanylate cyclase catalytic domain - - - 3.957e-321 1017.0
TH1_k127_644091_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000159 267.0
TH1_k127_644091_2 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00004089 48.0
TH1_k127_6469020_0 AAA domain - - - 2.918e-285 903.0
TH1_k127_6469020_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.944e-228 715.0
TH1_k127_6469020_10 Methylamine dehydrogenase, L chain K15228 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001274 260.0
TH1_k127_6469020_11 Thioredoxin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004918 259.0
TH1_k127_6469020_12 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000002556 261.0
TH1_k127_6469020_13 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001345 253.0
TH1_k127_6469020_14 Nicotinamidase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000001498 238.0
TH1_k127_6469020_15 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000000000000000652 175.0
TH1_k127_6469020_16 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000003622 155.0
TH1_k127_6469020_17 Exporters of the RND superfamily K07003 - - 0.00000000000000000000000000000000000006361 145.0
TH1_k127_6469020_18 Methylamine utilisation protein MauE - - - 0.000000000000000000000000000000000003292 151.0
TH1_k127_6469020_19 Cytochrome c - - - 0.00000000000000000000000002111 125.0
TH1_k127_6469020_2 Protein of unknown function (DUF1329) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 593.0
TH1_k127_6469020_20 protein histidine kinase activity - - - 0.000000000002325 78.0
TH1_k127_6469020_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 584.0
TH1_k127_6469020_4 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 535.0
TH1_k127_6469020_5 Protein of unknown function (DUF1302) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 538.0
TH1_k127_6469020_6 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 456.0
TH1_k127_6469020_7 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 440.0
TH1_k127_6469020_8 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 344.0
TH1_k127_6469020_9 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 288.0
TH1_k127_6479605_0 candidate b-glycosidase, glycoside hydrolase family 8 protein - - - 0.0000000000000000000000000000000000000000000000000000001886 209.0
TH1_k127_6479605_1 Beta-propeller repeat - - - 0.000000000000000000000226 107.0
TH1_k127_6492365_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.102e-203 644.0
TH1_k127_6492365_1 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 384.0
TH1_k127_6492365_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 361.0
TH1_k127_6492365_3 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000001703 215.0
TH1_k127_6492365_4 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000001622 190.0
TH1_k127_6492365_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000001254 120.0
TH1_k127_6492365_6 Bacterial-like globin K06886 - - 0.000000000000000000000000001119 113.0
TH1_k127_6492365_7 AAA domain - - - 0.00000000000000000000000003655 125.0
TH1_k127_6492365_8 - - - - 0.0002215 51.0
TH1_k127_6509427_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 385.0
TH1_k127_6509427_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000461 257.0
TH1_k127_6509427_2 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000006238 55.0
TH1_k127_65273_0 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 4.262e-248 778.0
TH1_k127_65273_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 9.189e-198 632.0
TH1_k127_65273_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 484.0
TH1_k127_65273_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 311.0
TH1_k127_65273_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003146 246.0
TH1_k127_65273_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000004375 232.0
TH1_k127_6530879_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 501.0
TH1_k127_6530879_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001194 273.0
TH1_k127_6530879_2 ChaC-like protein K07232 - - 0.0000000000000000006464 92.0
TH1_k127_6550703_0 enoyl-CoA hydratase K15513 - 4.1.2.44 2.067e-265 827.0
TH1_k127_6550703_1 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 5.849e-256 802.0
TH1_k127_6550703_10 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 363.0
TH1_k127_6550703_11 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 348.0
TH1_k127_6550703_12 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 338.0
TH1_k127_6550703_13 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 352.0
TH1_k127_6550703_14 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 293.0
TH1_k127_6550703_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002288 231.0
TH1_k127_6550703_16 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000001066 230.0
TH1_k127_6550703_17 Domain of unknown function (DUF4863) - - - 0.0000000000000000000000000000000000000000000000000000000001397 207.0
TH1_k127_6550703_18 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000000000000001898 201.0
TH1_k127_6550703_19 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000001815 206.0
TH1_k127_6550703_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 6.537e-208 677.0
TH1_k127_6550703_20 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000000000000000000000000006389 156.0
TH1_k127_6550703_21 thioesterase K01075 - 3.1.2.23 0.000000000000000000000000000000000004735 141.0
TH1_k127_6550703_22 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000002116 138.0
TH1_k127_6550703_23 Rubrerythrin - - - 0.00000000000000000000000000000005227 143.0
TH1_k127_6550703_24 Protein conserved in bacteria - - - 0.000000000000000002284 88.0
TH1_k127_6550703_3 NADH flavin oxidoreductase NADH oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 545.0
TH1_k127_6550703_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 524.0
TH1_k127_6550703_5 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 516.0
TH1_k127_6550703_6 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 432.0
TH1_k127_6550703_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 421.0
TH1_k127_6550703_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 417.0
TH1_k127_6550703_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 419.0
TH1_k127_6553291_0 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 338.0
TH1_k127_6553291_1 Tetratricopeptide repeat K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 302.0
TH1_k127_6585332_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1229.0
TH1_k127_6585332_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 5.109e-273 863.0
TH1_k127_6585332_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.814e-237 743.0
TH1_k127_6585332_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 3.901e-220 688.0
TH1_k127_6585332_4 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 430.0
TH1_k127_6585332_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000001481 213.0
TH1_k127_6585332_6 bacterial (prokaryotic) histone like domain - - - 0.000000000000000000000000000000004574 133.0
TH1_k127_6585332_7 - - - - 0.00000001552 59.0
TH1_k127_6585332_8 Domain of unknown function (DUF4124) - - - 0.00000008204 61.0
TH1_k127_6585332_9 - - - - 0.00000008907 55.0
TH1_k127_66168_0 Belongs to the TPP enzyme family K03852 - 2.3.3.15 1.399e-276 861.0
TH1_k127_66168_1 Transglycosylase SLT domain - - - 6.767e-204 645.0
TH1_k127_66168_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 593.0
TH1_k127_66168_3 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 445.0
TH1_k127_66168_4 Cytochrome B561 K12262 - - 0.0000000000000000000000000000000000003087 148.0
TH1_k127_6653110_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1303.0
TH1_k127_6653110_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.742e-299 939.0
TH1_k127_6653110_10 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000609 166.0
TH1_k127_6653110_11 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000005751 123.0
TH1_k127_6653110_12 DnaJ homolog subfamily B member K09517 GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0012505,GO:0016020,GO:0031347,GO:0031349,GO:0031974,GO:0032991,GO:0034663,GO:0035821,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044003,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052033,GO:0052166,GO:0052167,GO:0052169,GO:0052173,GO:0052200,GO:0052255,GO:0052257,GO:0052305,GO:0052306,GO:0052308,GO:0052509,GO:0052510,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0070013,GO:0071944,GO:0075136,GO:0080134 - 0.000179 51.0
TH1_k127_6653110_2 Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 509.0
TH1_k127_6653110_3 LytB protein K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 455.0
TH1_k127_6653110_4 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 429.0
TH1_k127_6653110_5 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 349.0
TH1_k127_6653110_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 338.0
TH1_k127_6653110_7 Belongs to the peptidase S24 family K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000001107 258.0
TH1_k127_6653110_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000008736 193.0
TH1_k127_6653110_9 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000005568 193.0
TH1_k127_6665543_0 Histidine kinase-like ATPases - - - 5.361e-248 814.0
TH1_k127_6665543_1 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 4.049e-239 743.0
TH1_k127_6665543_10 NnrS protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005514 262.0
TH1_k127_6665543_11 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000209 233.0
TH1_k127_6665543_12 Belongs to the CarA family K01956 GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000003839 213.0
TH1_k127_6665543_13 PFAM response regulator receiver K11443 - - 0.000000000000000000000000000000114 131.0
TH1_k127_6665543_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000000007722 113.0
TH1_k127_6665543_15 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000001047 107.0
TH1_k127_6665543_16 - - - - 0.0000000000000000866 87.0
TH1_k127_6665543_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 553.0
TH1_k127_6665543_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 490.0
TH1_k127_6665543_4 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 449.0
TH1_k127_6665543_5 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 412.0
TH1_k127_6665543_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 367.0
TH1_k127_6665543_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 308.0
TH1_k127_6665543_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 290.0
TH1_k127_6665543_9 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007787 266.0
TH1_k127_66721_0 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 2.487e-263 819.0
TH1_k127_66721_1 - - - - 0.00000001363 59.0
TH1_k127_6697904_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 572.0
TH1_k127_6697904_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 437.0
TH1_k127_6697904_2 KR domain K00059 - 1.1.1.100 0.0000000007431 61.0
TH1_k127_6719713_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.697e-264 827.0
TH1_k127_6719713_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 3.445e-205 658.0
TH1_k127_6719713_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 587.0
TH1_k127_6719713_3 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 415.0
TH1_k127_6719713_4 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 400.0
TH1_k127_6719713_5 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.00003737 50.0
TH1_k127_672348_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 420.0
TH1_k127_672348_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000002888 142.0
TH1_k127_672348_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000001942 92.0
TH1_k127_672348_3 ThiS family K03154 - - 0.000000000000001453 82.0
TH1_k127_672348_4 - - - - 0.0000000009955 68.0
TH1_k127_6730955_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 596.0
TH1_k127_6730955_1 Glutathione S-transferase K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 333.0
TH1_k127_6730955_2 PFAM Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000101 259.0
TH1_k127_6793636_0 Sulfatase K01130 - 3.1.6.1 0.0 1018.0
TH1_k127_6794319_0 NADH:flavin oxidoreductase / NADH oxidase family K00219,K09461 - 1.14.13.40,1.3.1.34 3.522e-305 945.0
TH1_k127_6794319_1 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004117 235.0
TH1_k127_688568_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 537.0
TH1_k127_688568_1 Belongs to the peptidase S1C family K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 418.0
TH1_k127_688568_10 Nucleotide transport and metabolism Carbohydrate transport and metabolism General function prediction only K02503 - - 0.00000000000000000000000000000000000000000000000396 175.0
TH1_k127_688568_11 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000002265 166.0
TH1_k127_688568_12 Psort location Cytoplasmic, score K01523 - 3.6.1.31 0.0000000000000000000000000000000001641 136.0
TH1_k127_688568_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000005079 119.0
TH1_k127_688568_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000003143 103.0
TH1_k127_688568_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 400.0
TH1_k127_688568_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 355.0
TH1_k127_688568_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 357.0
TH1_k127_688568_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 310.0
TH1_k127_688568_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 315.0
TH1_k127_688568_7 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 310.0
TH1_k127_688568_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004046 274.0
TH1_k127_688568_9 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000002052 196.0
TH1_k127_6918940_0 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 289.0
TH1_k127_6918940_1 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007799 296.0
TH1_k127_6918940_2 Glycosyl transferase family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000534 241.0
TH1_k127_6918940_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000001001 137.0
TH1_k127_694095_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 468.0
TH1_k127_694095_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000002316 246.0
TH1_k127_6946307_0 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661,K07536 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 510.0
TH1_k127_6946307_1 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 461.0
TH1_k127_6946307_2 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 404.0
TH1_k127_6946307_3 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 364.0
TH1_k127_6946307_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001817 280.0
TH1_k127_6985775_0 Protein of unknown function (DUF3604) - - - 1.287e-243 766.0
TH1_k127_703842_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1273.0
TH1_k127_703842_1 Pyridine nucleotide-disulphide oxidoreductase - - - 3.747e-296 923.0
TH1_k127_703842_2 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 8.248e-257 807.0
TH1_k127_703842_3 PFAM Thiamine pyrophosphate K00170,K18356 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 520.0
TH1_k127_703842_4 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 297.0
TH1_k127_703842_5 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000002745 257.0
TH1_k127_703842_6 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000000000000004326 169.0
TH1_k127_7075968_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 1.049e-308 954.0
TH1_k127_7075968_1 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 8.881e-255 796.0
TH1_k127_7075968_10 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000003593 239.0
TH1_k127_7075968_11 transcriptional regulator AsnC family - - - 0.000000000000000000000000000000000000000000000000000000000000000404 223.0
TH1_k127_7075968_12 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000007984 203.0
TH1_k127_7075968_13 Glycosyl transferase family, helical bundle domain K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000001379 171.0
TH1_k127_7075968_14 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.0000000000000000000000000000006039 125.0
TH1_k127_7075968_15 Cytochrome c K08738 - - 0.000000000000000000000000001286 116.0
TH1_k127_7075968_16 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000004483 87.0
TH1_k127_7075968_17 - - - - 0.0000000000009551 72.0
TH1_k127_7075968_2 4Fe-4S single cluster domain - - - 1.344e-203 637.0
TH1_k127_7075968_3 cytochrome d1 heme K19345 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 544.0
TH1_k127_7075968_4 peptidase, U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 513.0
TH1_k127_7075968_5 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 456.0
TH1_k127_7075968_6 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 344.0
TH1_k127_7075968_7 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 327.0
TH1_k127_7075968_8 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 314.0
TH1_k127_7075968_9 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 295.0
TH1_k127_7112421_0 Transposase K07481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 362.0
TH1_k127_7112421_1 Dehydrogenase - - - 0.00000000000000000000003926 100.0
TH1_k127_7112421_2 HAF family - - - 0.00002848 49.0
TH1_k127_7182935_0 asparaginyl-tRNA synthetase K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 552.0
TH1_k127_7182935_1 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 345.0
TH1_k127_7182935_2 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 302.0
TH1_k127_7182935_3 TIGRFAM yecA family protein K07039 - - 0.0000000000000000000000000000000052 141.0
TH1_k127_7258973_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 603.0
TH1_k127_7258973_1 synthesis repressor, PhaR - - - 0.000000000000000000000000000000000000000000000000000000000000000002458 231.0
TH1_k127_7258973_2 Phasin protein - - - 0.00000000000000000000000000009708 123.0
TH1_k127_72802_0 PFAM ATP-binding region ATPase domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 316.0
TH1_k127_72802_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000001389 104.0
TH1_k127_7300986_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1740.0
TH1_k127_7300986_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1010.0
TH1_k127_7300986_10 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000004339 100.0
TH1_k127_7300986_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 573.0
TH1_k127_7300986_3 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 548.0
TH1_k127_7300986_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 337.0
TH1_k127_7300986_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000004337 248.0
TH1_k127_7300986_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000001149 235.0
TH1_k127_7300986_7 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000006572 202.0
TH1_k127_7300986_8 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000001203 118.0
TH1_k127_7300986_9 RNA-binding protein containing KH domain possibly ribosomal protein - - - 0.000000000000000000000000001044 117.0
TH1_k127_7303015_0 Belongs to the DEAD box helicase family - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 499.0
TH1_k127_7303015_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 359.0
TH1_k127_7303015_2 RHS Repeat - - - 0.0000000000000000000134 108.0
TH1_k127_7303015_3 cellulose binding K01179 - 3.2.1.4 0.0000000000000001287 94.0
TH1_k127_7303015_4 Fibronectin type III domain - - - 0.00000000001114 78.0
TH1_k127_7303015_5 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000004187 68.0
TH1_k127_7303015_6 Caspase domain - - - 0.0000000007278 64.0
TH1_k127_7305180_0 Prolyl oligopeptidase family - - - 3.157e-202 651.0
TH1_k127_7305180_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 557.0
TH1_k127_7305180_10 Periplasmic Protein - GO:0003674,GO:0004857,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0016020,GO:0019867,GO:0030234,GO:0030312,GO:0030313,GO:0031975,GO:0043086,GO:0044092,GO:0044462,GO:0044464,GO:0050790,GO:0060241,GO:0065007,GO:0065009,GO:0071944,GO:0098772 - 0.00001034 56.0
TH1_k127_7305180_2 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 550.0
TH1_k127_7305180_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 503.0
TH1_k127_7305180_4 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 368.0
TH1_k127_7305180_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000008289 255.0
TH1_k127_7305180_6 CHAD - - - 0.0000000000000000000005013 106.0
TH1_k127_7305180_7 PFAM PsiF repeat protein - - - 0.00000000000000000005347 96.0
TH1_k127_7305180_8 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000008784 93.0
TH1_k127_7305180_9 KTSC domain - - - 0.00000000000000001377 83.0
TH1_k127_7325250_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 5.716e-199 632.0
TH1_k127_7325250_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 497.0
TH1_k127_7325250_2 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 407.0
TH1_k127_7325250_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 371.0
TH1_k127_7325250_4 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000009331 194.0
TH1_k127_7325250_5 Protein of unknown function (DUF2726) - - - 0.00004969 53.0
TH1_k127_7332810_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 534.0
TH1_k127_7332810_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 316.0
TH1_k127_7332810_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000005464 229.0
TH1_k127_7332810_3 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000001207 206.0
TH1_k127_7333970_0 PFAM extracellular solute-binding protein family 1 K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 505.0
TH1_k127_7333970_1 Binding-protein-dependent transport system inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 436.0
TH1_k127_7333970_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11076 - - 0.0000000000000000000000000000000000000000000004078 172.0
TH1_k127_7336397_0 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 411.0
TH1_k127_7336397_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 356.0
TH1_k127_7336397_2 Belongs to the DegT DnrJ EryC1 family K20429 - 2.6.1.33 0.000000000000000000000000000000000000000000003279 168.0
TH1_k127_7336397_3 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000001048 144.0
TH1_k127_7336397_4 Membrane - - - 0.000000000001664 72.0
TH1_k127_7338476_0 FAD dependent oxidoreductase - - - 0.0 1090.0
TH1_k127_7338476_1 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.067e-240 754.0
TH1_k127_7338476_10 IclR family transcriptional regulator K13641 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004498 284.0
TH1_k127_7338476_11 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003842 272.0
TH1_k127_7338476_12 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000852 237.0
TH1_k127_7338476_13 Domain of unknown function (DUF4743) - - - 0.000000000000000000000000000000000000000000000000000000000000001741 228.0
TH1_k127_7338476_14 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.000000000000000000000000000000000000000000000000000000003687 204.0
TH1_k127_7338476_15 ABC transporter substrate binding protein - - - 0.00000000000000000000000000000000000000000000000000001105 202.0
TH1_k127_7338476_16 Cysteine-rich CWC - - - 0.0000000000002581 77.0
TH1_k127_7338476_2 Na Pi-cotransporter II-related protein K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 618.0
TH1_k127_7338476_3 permease K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 612.0
TH1_k127_7338476_4 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 584.0
TH1_k127_7338476_5 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 585.0
TH1_k127_7338476_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K00836 - 2.6.1.19,2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 567.0
TH1_k127_7338476_7 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 481.0
TH1_k127_7338476_8 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 452.0
TH1_k127_7338476_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 396.0
TH1_k127_7340011_0 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009688 406.0
TH1_k127_7340011_1 Protein of unknown function (DUF3015) - - - 0.0000000000000000000000000000000000000000000000000000000000006629 217.0
TH1_k127_7340011_2 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000001242 213.0
TH1_k127_7344009_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.087e-219 690.0
TH1_k127_7344009_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 451.0
TH1_k127_7344009_10 - - - - 0.000000007043 57.0
TH1_k127_7344009_2 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 318.0
TH1_k127_7344009_4 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001841 239.0
TH1_k127_7344009_5 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000002314 212.0
TH1_k127_7344009_6 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000003104 203.0
TH1_k127_7344009_7 Helix-turn-helix K21498 - - 0.00000000000000000000000000000000000002339 150.0
TH1_k127_7344009_8 SAF - - - 0.0000000000000000000006487 98.0
TH1_k127_7344009_9 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000001268 79.0
TH1_k127_7344882_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1223.0
TH1_k127_7344882_1 protein synthesis factor, GTP-binding K06207 - - 1.423e-297 927.0
TH1_k127_7344882_10 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000134 282.0
TH1_k127_7344882_11 PFAM permease YjgP YjgQ family protein K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000002233 252.0
TH1_k127_7344882_12 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000002446 226.0
TH1_k127_7344882_13 Magnesium transport protein CorA K03284 - - 0.000000000000000000000000000000000000000000000000000000000005798 222.0
TH1_k127_7344882_14 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000005398 196.0
TH1_k127_7344882_15 Protein of unknown function (DUF3299) K09950 - - 0.000000000000000000000000000000005453 141.0
TH1_k127_7344882_16 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000000001447 132.0
TH1_k127_7344882_17 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000002026 125.0
TH1_k127_7344882_18 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000003425 126.0
TH1_k127_7344882_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.012e-207 654.0
TH1_k127_7344882_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 6.038e-203 642.0
TH1_k127_7344882_4 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 566.0
TH1_k127_7344882_5 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 530.0
TH1_k127_7344882_6 DNA recombination protein RmuC K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 439.0
TH1_k127_7344882_7 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006621 360.0
TH1_k127_7344882_8 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 362.0
TH1_k127_7344882_9 Permease YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 311.0
TH1_k127_7352602_0 Protein conserved in bacteria K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 611.0
TH1_k127_7352602_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 587.0
TH1_k127_7352602_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000007275 213.0
TH1_k127_7352602_11 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000004639 154.0
TH1_k127_7352602_12 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000006093 110.0
TH1_k127_7352602_13 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000002955 91.0
TH1_k127_7352602_2 Protein of unknown function (DUF993) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 538.0
TH1_k127_7352602_3 Putative oxidoreductase C terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 542.0
TH1_k127_7352602_4 Glutaredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 485.0
TH1_k127_7352602_5 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 464.0
TH1_k127_7352602_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 454.0
TH1_k127_7352602_7 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 450.0
TH1_k127_7352602_8 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 402.0
TH1_k127_7352602_9 Domain of unknown function (DUF4202) - - - 0.000000000000000000000000000000000000000000000000000000000000000002372 232.0
TH1_k127_7360699_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K18355 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 593.0
TH1_k127_7360699_1 Pyridine nucleotide-disulphide oxidoreductase K18359 - 1.2.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 483.0
TH1_k127_7360699_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 433.0
TH1_k127_7360699_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009589 391.0
TH1_k127_7360699_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K18357 - 1.2.1.58 0.000000000000000000000000000000000000000000000000000000000000000000000001562 252.0
TH1_k127_7360699_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000347 241.0
TH1_k127_7360699_6 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000001536 216.0
TH1_k127_7360699_7 4Fe-4S binding domain K18358 - 1.2.1.58 0.000000000000000000000000000000000000000002197 164.0
TH1_k127_7361630_0 Pfam Sulfatase K01130 - 3.1.6.1 4.62e-303 936.0
TH1_k127_7361630_1 Arylsulfatase K01130 - 3.1.6.1 8.102e-213 671.0
TH1_k127_7361630_2 radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 521.0
TH1_k127_7361630_3 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 449.0
TH1_k127_7361630_4 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 386.0
TH1_k127_7361630_5 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000000000000000000000000000000004582 185.0
TH1_k127_7361630_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.000000000000000000000000004636 112.0
TH1_k127_7361630_7 membrane - - - 0.000000000000000003657 91.0
TH1_k127_7361630_8 - - - - 0.00000000000001055 85.0
TH1_k127_737468_0 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 529.0
TH1_k127_737468_1 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008093 272.0
TH1_k127_737468_2 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000001025 65.0
TH1_k127_7405605_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.946e-287 904.0
TH1_k127_7405605_1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 327.0
TH1_k127_7405605_2 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 311.0
TH1_k127_7405605_3 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 308.0
TH1_k127_7405605_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000001218 88.0
TH1_k127_7405605_5 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000001472 55.0
TH1_k127_7412224_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1512.0
TH1_k127_7412224_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1259.0
TH1_k127_7412224_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002265 264.0
TH1_k127_7412224_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000007865 227.0
TH1_k127_7412224_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000005799 95.0
TH1_k127_7423770_0 FAD binding domain K00394 - 1.8.99.2 0.0 1097.0
TH1_k127_7423770_1 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 295.0
TH1_k127_7433154_0 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 284.0
TH1_k127_7433154_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000005141 235.0
TH1_k127_7433154_2 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000004617 130.0
TH1_k127_7433154_3 - - - - 0.000000000000000001215 95.0
TH1_k127_7463539_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1024.0
TH1_k127_7463539_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.665e-229 725.0
TH1_k127_7463539_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 446.0
TH1_k127_7463539_3 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 366.0
TH1_k127_7463539_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 275.0
TH1_k127_7463539_5 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000008599 186.0
TH1_k127_7463539_6 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.0000000000000000000000000000000000000000000000004982 178.0
TH1_k127_7463539_7 phenylacetic acid degradation protein paaD K02614 - - 0.00000000000000000000000000000000000004813 147.0
TH1_k127_7463539_8 CRP FNR family - - - 0.0002547 45.0
TH1_k127_7470559_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 389.0
TH1_k127_7470559_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 355.0
TH1_k127_7470559_2 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 320.0
TH1_k127_7470559_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009341 288.0
TH1_k127_7470559_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000002762 61.0
TH1_k127_7470667_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 1.593e-224 705.0
TH1_k127_7470667_1 Heavy metal transport detoxification protein K17686,K19597 - 3.6.3.54 2.593e-224 718.0
TH1_k127_7470667_10 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000879 151.0
TH1_k127_7470667_11 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000008306 76.0
TH1_k127_7470667_12 Heavy metal-associated domain protein K07213 - - 0.00000000004339 70.0
TH1_k127_7470667_13 - - - - 0.0000001547 53.0
TH1_k127_7470667_14 Amidohydrolase family - - - 0.000001289 53.0
TH1_k127_7470667_15 - - - - 0.0002688 48.0
TH1_k127_7470667_2 Cytochrome c554 and c-prime - - - 2.846e-220 734.0
TH1_k127_7470667_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 571.0
TH1_k127_7470667_4 TrkA-N domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 569.0
TH1_k127_7470667_5 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 416.0
TH1_k127_7470667_6 phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000007229 231.0
TH1_k127_7470667_7 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000001046 248.0
TH1_k127_7470667_8 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000000000000000001177 209.0
TH1_k127_7470667_9 - - - - 0.0000000000000000000000000000000000000000000000000004575 186.0
TH1_k127_7473972_0 PFAM extracellular solute-binding protein family 5 K12368 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 565.0
TH1_k127_7473972_1 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 368.0
TH1_k127_7481718_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 386.0
TH1_k127_7481718_1 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 297.0
TH1_k127_7489957_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.475e-237 747.0
TH1_k127_7489957_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.371e-196 632.0
TH1_k127_7489957_10 Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001568 254.0
TH1_k127_7489957_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 577.0
TH1_k127_7489957_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 510.0
TH1_k127_7489957_4 pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 433.0
TH1_k127_7489957_5 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 400.0
TH1_k127_7489957_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 358.0
TH1_k127_7489957_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 344.0
TH1_k127_7489957_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 309.0
TH1_k127_7489957_9 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001524 281.0
TH1_k127_7495425_0 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing - - - 0.0 1115.0
TH1_k127_7495425_1 PFAM Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 4.823e-218 689.0
TH1_k127_7495425_10 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001009 270.0
TH1_k127_7495425_11 Bacterial transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000004709 213.0
TH1_k127_7495425_12 Methylmuconolactone methyl-isomerase - - - 0.000000000000000000000000000000000000000000002295 173.0
TH1_k127_7495425_13 B12- binding domain protein K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000002261 162.0
TH1_k127_7495425_14 amidohydrolase K07045 - - 0.000000000000000000000000000000000000001089 159.0
TH1_k127_7495425_15 Nitroreductase family - - - 0.000000000000000000000001106 113.0
TH1_k127_7495425_2 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 2.124e-209 665.0
TH1_k127_7495425_3 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 1.254e-202 639.0
TH1_k127_7495425_4 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007235 514.0
TH1_k127_7495425_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 479.0
TH1_k127_7495425_6 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 400.0
TH1_k127_7495425_7 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 361.0
TH1_k127_7495425_8 abc transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 317.0
TH1_k127_7495425_9 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003057 275.0
TH1_k127_7507541_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K03336 - 3.7.1.22 9.032e-278 866.0
TH1_k127_7507541_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 2.359e-228 719.0
TH1_k127_7507541_2 Belongs to the thiolase family K00632,K07550 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 617.0
TH1_k127_7507541_3 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 430.0
TH1_k127_7507541_4 KduI/IolB family K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 361.0
TH1_k127_7507541_5 PIN domain - - - 0.00000000000000000000000000000000000000001063 161.0
TH1_k127_7507541_6 Uncharacterized protein conserved in bacteria (DUF2090) K03338 - 2.7.1.92 0.000000000000000000000000000000000000003335 148.0
TH1_k127_7507541_7 - - - - 0.000000003931 61.0
TH1_k127_7507541_8 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000005657 62.0
TH1_k127_7533927_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1838.0
TH1_k127_7533927_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 5.818e-271 848.0
TH1_k127_7533927_10 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 443.0
TH1_k127_7533927_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 421.0
TH1_k127_7533927_12 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 406.0
TH1_k127_7533927_13 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 408.0
TH1_k127_7533927_14 Exonuclease VII, large subunit K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 409.0
TH1_k127_7533927_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 408.0
TH1_k127_7533927_16 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 370.0
TH1_k127_7533927_17 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 343.0
TH1_k127_7533927_18 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 323.0
TH1_k127_7533927_19 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 323.0
TH1_k127_7533927_2 glutaminyl-tRNA K01886 - 6.1.1.18 1.625e-262 822.0
TH1_k127_7533927_20 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 311.0
TH1_k127_7533927_21 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001037 285.0
TH1_k127_7533927_22 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005805 281.0
TH1_k127_7533927_23 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009796 268.0
TH1_k127_7533927_24 Psort location CytoplasmicMembrane, score 10.00 K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006074 257.0
TH1_k127_7533927_25 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000766 246.0
TH1_k127_7533927_26 UPF0761 membrane protein K07058 - - 0.0000000000000000000000000000000000000000000000000001091 197.0
TH1_k127_7533927_27 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000001061 174.0
TH1_k127_7533927_28 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000000000000000003279 171.0
TH1_k127_7533927_29 Biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000001975 153.0
TH1_k127_7533927_3 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 8.22e-248 780.0
TH1_k127_7533927_30 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000001415 136.0
TH1_k127_7533927_31 Adenylosuccinate lyase C-terminal K01756 - 4.3.2.2 0.00000000000000000000004746 99.0
TH1_k127_7533927_4 Sulfatase - - - 3.032e-196 646.0
TH1_k127_7533927_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.724e-194 617.0
TH1_k127_7533927_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 572.0
TH1_k127_7533927_7 response regulator K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 567.0
TH1_k127_7533927_8 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 488.0
TH1_k127_7533927_9 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 462.0
TH1_k127_7543855_0 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.0 1206.0
TH1_k127_7543855_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.467e-308 957.0
TH1_k127_7543855_10 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 316.0
TH1_k127_7543855_11 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 324.0
TH1_k127_7543855_12 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 312.0
TH1_k127_7543855_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 307.0
TH1_k127_7543855_14 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 297.0
TH1_k127_7543855_15 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 295.0
TH1_k127_7543855_16 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009267 281.0
TH1_k127_7543855_17 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001703 267.0
TH1_k127_7543855_18 helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000294 248.0
TH1_k127_7543855_19 Guanylate kinase homologues. K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000007571 245.0
TH1_k127_7543855_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 8.594e-285 891.0
TH1_k127_7543855_20 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000002913 225.0
TH1_k127_7543855_21 cheY-homologous receiver domain K02657 - - 0.000000000000000000000000000000000000000000000000000000000000006039 220.0
TH1_k127_7543855_22 - - - - 0.00000000000000000000000000000000000000000000000000000006929 204.0
TH1_k127_7543855_23 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000001198 189.0
TH1_k127_7543855_24 RESPONSE REGULATOR receiver K02658 - - 0.0000000000000000000000000000000000000000000000000013 186.0
TH1_k127_7543855_25 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000002531 162.0
TH1_k127_7543855_26 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000001967 152.0
TH1_k127_7543855_27 Chemotaxis signal transduction protein K02659 - - 0.00000000000000000000000000000000006019 139.0
TH1_k127_7543855_28 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000006021 111.0
TH1_k127_7543855_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 7.153e-243 761.0
TH1_k127_7543855_4 Ammonium Transporter Family K03320,K06580 - - 4.543e-222 693.0
TH1_k127_7543855_5 dihydroorotase K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 603.0
TH1_k127_7543855_6 Methyl-accepting chemotaxis protein K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 600.0
TH1_k127_7543855_7 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 548.0
TH1_k127_7543855_8 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 511.0
TH1_k127_7543855_9 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 422.0
TH1_k127_7553066_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 2.464e-295 915.0
TH1_k127_7553066_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 383.0
TH1_k127_7553066_2 citrate synthase K01647 - 2.3.3.1 0.000000000000000000000000000009214 119.0
TH1_k127_7554808_0 FtsX-like permease family K02004 - - 6.938e-238 761.0
TH1_k127_7554808_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.119e-224 713.0
TH1_k127_7554808_10 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003683 261.0
TH1_k127_7554808_11 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000002558 223.0
TH1_k127_7554808_12 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000000000000000000011 206.0
TH1_k127_7554808_13 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000004231 188.0
TH1_k127_7554808_14 Beta/gamma crystallins - - - 0.000000000000000000000000000000000000000000002706 177.0
TH1_k127_7554808_15 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000000000000000000004572 160.0
TH1_k127_7554808_16 NfeD-like C-terminal, partner-binding - - - 0.0000000000000000000000000004471 118.0
TH1_k127_7554808_2 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.889e-208 656.0
TH1_k127_7554808_3 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 538.0
TH1_k127_7554808_4 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 475.0
TH1_k127_7554808_5 C-terminal region of band_7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 430.0
TH1_k127_7554808_6 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 413.0
TH1_k127_7554808_7 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 383.0
TH1_k127_7554808_8 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 327.0
TH1_k127_7554808_9 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009656 272.0
TH1_k127_7578267_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 4.992e-202 638.0
TH1_k127_7578267_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000003713 201.0
TH1_k127_7578267_2 - - - - 0.00000000000000000000000000000000000001884 157.0
TH1_k127_7578267_3 Protein of unknown function (DUF3301) - - - 0.00000000000000000000008488 103.0
TH1_k127_7620137_0 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 291.0
TH1_k127_7620137_1 Glycine cleavage system regulatory protein - - - 0.00000000000000000000000000000000000000000000005081 180.0
TH1_k127_7620137_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000006749 81.0
TH1_k127_7626728_0 TIGRFAM malate synthase A K01638 - 2.3.3.9 2.489e-260 811.0
TH1_k127_7626728_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.47e-245 769.0
TH1_k127_7626728_10 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000003449 236.0
TH1_k127_7626728_11 Evidence 4 Homologs of previously reported genes of K09700 - - 0.000000000000000000000000000000000000000001485 158.0
TH1_k127_7626728_2 Cysteine-rich domain - - - 1.276e-217 683.0
TH1_k127_7626728_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 582.0
TH1_k127_7626728_4 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 349.0
TH1_k127_7626728_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 323.0
TH1_k127_7626728_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 302.0
TH1_k127_7626728_7 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009947 251.0
TH1_k127_7626728_8 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004192 251.0
TH1_k127_7626728_9 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000002491 237.0
TH1_k127_7653062_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1038.0
TH1_k127_7653062_1 Nickel-dependent hydrogenase K06281 - 1.12.99.6 5.442e-315 972.0
TH1_k127_7653062_2 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 319.0
TH1_k127_7653062_3 Prokaryotic cytochrome b561 K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001715 271.0
TH1_k127_7653062_4 PFAM cytoplasmic chaperone TorD family protein - - - 0.000000000000000000000000000000000005357 146.0
TH1_k127_7653062_5 Helix-turn-helix K21498 - - 0.00000000000000000000003542 115.0
TH1_k127_7675321_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 502.0
TH1_k127_7675321_1 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003501 244.0
TH1_k127_7675321_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000006823 171.0
TH1_k127_7710168_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 6.734e-321 993.0
TH1_k127_7710168_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000959 502.0
TH1_k127_771325_0 4-alpha-glucanotransferase K01214,K02438 - 3.2.1.196,3.2.1.68 0.0 1428.0
TH1_k127_771325_1 ABC-type Fe3 transport system permease component K02011 - - 1.225e-254 805.0
TH1_k127_771325_2 COG1960 Acyl-CoA dehydrogenases K20035 - - 3.217e-235 741.0
TH1_k127_771325_3 Nucleotidyl transferase K00975 - 2.7.7.27 4.916e-206 646.0
TH1_k127_771325_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.807e-196 625.0
TH1_k127_771325_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 445.0
TH1_k127_771325_6 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 420.0
TH1_k127_771325_7 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 403.0
TH1_k127_771325_8 Bacterial extracellular solute-binding protein K02012,K11081 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 372.0
TH1_k127_771325_9 - - - - 0.000000000000000000000000496 120.0
TH1_k127_7762436_0 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 327.0
TH1_k127_7762436_1 protein conserved in bacteria K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 325.0
TH1_k127_7813193_0 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 7.158e-279 865.0
TH1_k127_7813193_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.595e-251 779.0
TH1_k127_7813193_2 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 412.0
TH1_k127_7838968_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.851e-264 827.0
TH1_k127_7838968_1 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005044 279.0
TH1_k127_7838968_2 Thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000001767 153.0
TH1_k127_7851375_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 410.0
TH1_k127_7851375_1 Glycosyltransferase Family 4 - - - 0.0000000002301 62.0
TH1_k127_8054469_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 5.652e-315 970.0
TH1_k127_8054469_1 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848,K20906 - 5.4.99.2,5.4.99.64 1.615e-281 886.0
TH1_k127_8054469_10 Protein of unknown function (DUF3106) - - - 0.000000000000000000000001593 114.0
TH1_k127_8054469_11 PFAM RDD domain containing protein - - - 0.000000000000000000003016 105.0
TH1_k127_8054469_12 Protein of unknown function (DUF3619) - - - 0.000000002604 67.0
TH1_k127_8054469_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 3.729e-240 750.0
TH1_k127_8054469_3 Thioredoxin-like K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 391.0
TH1_k127_8054469_4 ArgK protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 362.0
TH1_k127_8054469_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002504 277.0
TH1_k127_8054469_6 RNA polymerase K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000009626 250.0
TH1_k127_8054469_7 COG2185 Methylmalonyl-CoA mutase, C-terminal domain subunit (cobalamin-binding) K01849,K20907 - 5.4.99.2,5.4.99.64 0.0000000000000000000000000000000000000000000000000000000002334 208.0
TH1_k127_8054469_8 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000007437 188.0
TH1_k127_8054469_9 - - - - 0.000000000000000000000001475 113.0
TH1_k127_8114606_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 316.0
TH1_k127_8114606_1 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 292.0
TH1_k127_8114606_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000006745 209.0
TH1_k127_8114606_3 rieske 2fe-2s K00499 - 1.14.15.7 0.000000000000000000000000000000000004911 137.0
TH1_k127_8192855_0 glycosyl transferase family 2 K20444 - - 2.5e-323 1036.0
TH1_k127_8192855_1 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000007675 163.0
TH1_k127_8192855_2 DUF218 domain - - - 0.00000000000000000000000000000000003927 142.0
TH1_k127_8220025_0 ABC-type multidrug transport system, ATPase and permease K06147 - - 8.422e-226 728.0
TH1_k127_8220025_1 Aminotransferase class I and II K00832 - 2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 565.0
TH1_k127_8220025_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000003536 166.0
TH1_k127_8220025_3 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000001586 132.0
TH1_k127_8220025_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000001714 68.0
TH1_k127_82630_0 Ftsk_gamma K03466 - - 6.462e-306 955.0
TH1_k127_82630_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 2.172e-267 852.0
TH1_k127_82630_10 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 300.0
TH1_k127_82630_11 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000000000000000000004855 230.0
TH1_k127_82630_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000003165 229.0
TH1_k127_82630_13 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000003915 205.0
TH1_k127_82630_14 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000002719 159.0
TH1_k127_82630_15 Smr domain - - - 0.000000000000000000000000000000000001289 155.0
TH1_k127_82630_16 SnoaL-like domain - - - 0.00000000000000000000000000001665 123.0
TH1_k127_82630_17 Zinc-finger domain - - - 0.000000000000000001836 95.0
TH1_k127_82630_2 Protein of unknown function - - - 5.912e-262 875.0
TH1_k127_82630_3 MgsA AAA+ ATPase C terminal K07478 - - 6.476e-195 616.0
TH1_k127_82630_4 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 601.0
TH1_k127_82630_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 597.0
TH1_k127_82630_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 501.0
TH1_k127_82630_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 459.0
TH1_k127_82630_8 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 364.0
TH1_k127_82630_9 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 322.0
TH1_k127_8274876_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1012.0
TH1_k127_8274876_1 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 3.16e-205 647.0
TH1_k127_8274876_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 484.0
TH1_k127_8274876_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 364.0
TH1_k127_8274876_4 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 346.0
TH1_k127_8274876_5 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001477 268.0
TH1_k127_8274876_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000001808 180.0
TH1_k127_8274876_7 Universal stress protein - - - 0.0000000000000000000000000498 112.0
TH1_k127_8274876_8 Domain of unknown function (DUF4160) - - - 0.0000000000013 79.0
TH1_k127_829006_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 348.0
TH1_k127_829006_1 PFAM NapC NirT cytochrome c K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 297.0
TH1_k127_829006_2 4Fe-4S binding domain K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001988 256.0
TH1_k127_829006_3 Domain of unknown function (DUF4160) - - - 0.00000000000000000000000000000000000000006092 152.0
TH1_k127_829006_4 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.0000000000000000000000000000000000000001861 162.0
TH1_k127_829006_5 Protein of unknown function (DUF2442) - - - 0.000000000000000000000009451 116.0
TH1_k127_8313030_0 Tripartite tricarboxylate transporter TctA family - - - 2.249e-253 790.0
TH1_k127_8313030_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.454e-252 780.0
TH1_k127_8313030_10 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000002474 147.0
TH1_k127_8313030_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000008832 128.0
TH1_k127_8313030_12 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000001027 117.0
TH1_k127_8313030_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 509.0
TH1_k127_8313030_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 484.0
TH1_k127_8313030_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 438.0
TH1_k127_8313030_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 319.0
TH1_k127_8313030_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 299.0
TH1_k127_8313030_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000008839 269.0
TH1_k127_8313030_8 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004299 258.0
TH1_k127_8313030_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000003237 194.0
TH1_k127_8364483_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 389.0
TH1_k127_8364483_1 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000000396 175.0
TH1_k127_8364483_2 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000005513 134.0
TH1_k127_8364483_4 - - - - 0.0003912 43.0
TH1_k127_8409701_0 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 437.0
TH1_k127_8409701_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 429.0
TH1_k127_8409701_2 Aminotransferase class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 372.0
TH1_k127_8409701_3 RES - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005949 256.0
TH1_k127_8409701_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000008145 248.0
TH1_k127_8409701_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000008907 247.0
TH1_k127_8409701_6 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000001839 183.0
TH1_k127_8409701_7 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000001606 131.0
TH1_k127_8532009_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.383e-253 788.0
TH1_k127_8532009_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 5.529e-253 788.0
TH1_k127_8532009_10 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001699 274.0
TH1_k127_8532009_11 Acetyltransferase (GNAT) domain K02348 - - 0.000000000000000000000000000000000000000000000008702 184.0
TH1_k127_8532009_12 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000007604 172.0
TH1_k127_8532009_13 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000002971 175.0
TH1_k127_8532009_14 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000006871 158.0
TH1_k127_8532009_15 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000002753 117.0
TH1_k127_8532009_2 Tripartite tricarboxylate transporter TctA family K07793 - - 1.004e-234 734.0
TH1_k127_8532009_3 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 565.0
TH1_k127_8532009_4 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 551.0
TH1_k127_8532009_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 513.0
TH1_k127_8532009_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 514.0
TH1_k127_8532009_7 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 470.0
TH1_k127_8532009_8 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 327.0
TH1_k127_8532009_9 TilS substrate binding domain K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 309.0
TH1_k127_8534666_0 Glutathione S-transferase, N-terminal domain K11208 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001853 266.0
TH1_k127_8534666_1 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.0000000000000000000000000000000000000000000000000000001406 203.0
TH1_k127_8534666_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000002674 128.0
TH1_k127_8534666_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000006527 60.0
TH1_k127_8534666_4 impB/mucB/samB family K14161 - - 0.00007058 50.0
TH1_k127_8551198_0 MMPL family K07003 - - 0.0 1047.0
TH1_k127_8551198_1 Protein of unknown function (DUF1329) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 576.0
TH1_k127_8551198_2 Protein of unknown function (DUF1302) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 550.0
TH1_k127_8551198_3 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005098 273.0
TH1_k127_8551198_4 Multicopper oxidase K22349 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000003549 202.0
TH1_k127_8551198_5 Thioesterase K07107 - - 0.0000000000000000000000000002309 120.0
TH1_k127_8551746_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 5.62e-316 978.0
TH1_k127_8551746_1 oxidoreductase DsbE K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005323 257.0
TH1_k127_8551746_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000005812 208.0
TH1_k127_8551746_3 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000004466 141.0
TH1_k127_8551746_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.000006658 50.0
TH1_k127_8551746_5 Cytochrome c-type biogenesis protein K02200 - - 0.0007961 44.0
TH1_k127_8578247_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1640.0
TH1_k127_8578247_1 Belongs to the peptidase M16 family K07263 - - 5.465e-278 884.0
TH1_k127_8578247_2 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 419.0
TH1_k127_8578247_3 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 342.0
TH1_k127_8578247_4 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 339.0
TH1_k127_8578247_5 Ankyrin repeats (3 copies) K06867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009136 257.0
TH1_k127_8578247_6 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000001108 205.0
TH1_k127_8578247_7 phenylacetic acid degradation protein paaD K02614 - - 0.0000004035 52.0
TH1_k127_8594872_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1175.0
TH1_k127_8594872_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1068.0
TH1_k127_8594872_2 Nucleotidyl transferase K00975 - 2.7.7.27 0.0000000000000000003484 94.0
TH1_k127_8618154_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 1.505e-241 758.0
TH1_k127_8618154_1 Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000002957 103.0
TH1_k127_8624011_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 3.031e-284 882.0
TH1_k127_8624011_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 4.151e-248 775.0
TH1_k127_8624011_10 Cytochrome c - - - 0.00000000000000000000000004901 114.0
TH1_k127_8624011_11 Protein of unknown function (DUF2788) - - - 0.000000000000000000000001323 104.0
TH1_k127_8624011_12 Dehydratase small subunit K13920 - 4.2.1.28 0.0000000000000000000004084 101.0
TH1_k127_8624011_13 Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC K01160 - 3.1.22.4 0.000001254 58.0
TH1_k127_8624011_2 Dehydratase large subunit K01699,K06120 - 4.2.1.28,4.2.1.30 8.552e-206 665.0
TH1_k127_8624011_3 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 597.0
TH1_k127_8624011_4 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 556.0
TH1_k127_8624011_5 Transporter K11688,K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 538.0
TH1_k127_8624011_6 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000002457 239.0
TH1_k127_8624011_7 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000003767 198.0
TH1_k127_8624011_8 Tripartite ATP-independent periplasmic transporter - - - 0.000000000000000000000000000000000000000000000000003514 195.0
TH1_k127_8624011_9 Dehydratase medium subunit K06121,K13919 - 4.2.1.28,4.2.1.30 0.000000000000000000000000000000000000002258 169.0
TH1_k127_8624107_0 Transcriptional regulator K03603,K05799 - - 3.37e-264 842.0
TH1_k127_8624107_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 7.283e-206 650.0
TH1_k127_8624107_2 PhoH-like phosphate starvation-inducible protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 450.0
TH1_k127_8624107_3 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 467.0
TH1_k127_8624107_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 324.0
TH1_k127_8624107_5 Periplasmic binding protein K02016,K06858 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003098 273.0
TH1_k127_8624107_6 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000001402 243.0
TH1_k127_8624107_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000007505 160.0
TH1_k127_8624107_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000001195 79.0
TH1_k127_8626171_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1328.0
TH1_k127_8626171_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.403e-299 943.0
TH1_k127_8626171_10 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 421.0
TH1_k127_8626171_11 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 417.0
TH1_k127_8626171_12 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 415.0
TH1_k127_8626171_13 Phosphorylase superfamily K00772,K03815 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 319.0
TH1_k127_8626171_14 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 316.0
TH1_k127_8626171_15 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 309.0
TH1_k127_8626171_16 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 304.0
TH1_k127_8626171_17 Cytidylate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005098 265.0
TH1_k127_8626171_18 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000008848 258.0
TH1_k127_8626171_19 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000004467 261.0
TH1_k127_8626171_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.886e-262 816.0
TH1_k127_8626171_20 Sodium Bile acid symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000007351 235.0
TH1_k127_8626171_21 OmpA family K03286 - - 0.00000000000000000000000000000000000000000000000003577 193.0
TH1_k127_8626171_22 Type II secretion system protein C K02452 - - 0.000174 53.0
TH1_k127_8626171_3 PFAM aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 530.0
TH1_k127_8626171_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 524.0
TH1_k127_8626171_5 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 515.0
TH1_k127_8626171_6 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 500.0
TH1_k127_8626171_7 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 458.0
TH1_k127_8626171_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 454.0
TH1_k127_8626171_9 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 427.0
TH1_k127_8630153_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138,K18303 - - 0.0 1193.0
TH1_k127_8630153_1 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 5.912e-252 786.0
TH1_k127_8630153_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000003306 201.0
TH1_k127_8630153_11 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000008695 176.0
TH1_k127_8630153_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000008387 167.0
TH1_k127_8630153_13 transcriptional regulator - - - 0.00000000000000000000000000000000000004669 152.0
TH1_k127_8630153_14 Tfp pilus assembly protein K02655 - - 0.000000000000000000000000000003461 134.0
TH1_k127_8630153_15 GYD domain - - - 0.0000000000000000000000000006425 118.0
TH1_k127_8630153_16 Type II transport protein GspH K08084 - - 0.000000000000000000000000002619 119.0
TH1_k127_8630153_17 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000000003749 127.0
TH1_k127_8630153_18 Pilus assembly protein PilX - - - 0.00000000000001795 87.0
TH1_k127_8630153_19 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000004554 74.0
TH1_k127_8630153_2 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 2.134e-213 668.0
TH1_k127_8630153_20 type IV pilus modification protein PilV K02671 - - 0.000000001275 69.0
TH1_k127_8630153_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 514.0
TH1_k127_8630153_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 319.0
TH1_k127_8630153_5 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 318.0
TH1_k127_8630153_6 fumarylacetoacetate hydrolase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 291.0
TH1_k127_8630153_7 Maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008218 273.0
TH1_k127_8630153_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000843 273.0
TH1_k127_8630153_9 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000002303 269.0
TH1_k127_8631848_0 AMP-binding enzyme K00666,K20034 - 6.2.1.44 2.927e-291 904.0
TH1_k127_8631848_1 Patatin-like phospholipase K07001 - - 4.829e-257 815.0
TH1_k127_8631848_2 AcrB/AcrD/AcrF family K07003 - - 6.509e-254 797.0
TH1_k127_8631848_3 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 2.047e-210 662.0
TH1_k127_8631848_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 577.0
TH1_k127_8631848_5 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 472.0
TH1_k127_8634927_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 509.0
TH1_k127_8634927_1 tRNA wobble cytosine modification - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 469.0
TH1_k127_8634927_10 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000007456 91.0
TH1_k127_8634927_11 - - - - 0.0001966 51.0
TH1_k127_8634927_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 326.0
TH1_k127_8634927_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 289.0
TH1_k127_8634927_4 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002784 280.0
TH1_k127_8634927_5 Pfam:DUF989 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009175 276.0
TH1_k127_8634927_6 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002604 282.0
TH1_k127_8634927_7 Disulfide bond isomerase protein N-terminus K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000005752 250.0
TH1_k127_8634927_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001781 168.0
TH1_k127_8634927_9 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000000000000000000000001496 173.0
TH1_k127_8639549_0 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 327.0
TH1_k127_8639549_1 Protein of unknown function (DUF3302) - - - 0.0000000000000000000000000000000000000001015 160.0
TH1_k127_8639549_2 Ion channel - - - 0.000000000000000000004769 93.0
TH1_k127_8656085_0 amine dehydrogenase activity - - - 3.364e-290 921.0
TH1_k127_8656085_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 394.0
TH1_k127_8656085_2 Protease prsW family - - - 0.00000000000000000000000000000000000000008749 168.0
TH1_k127_8682468_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 494.0
TH1_k127_8682468_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 400.0
TH1_k127_8682468_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000001367 115.0
TH1_k127_8695522_0 ATPase (AAA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 391.0
TH1_k127_8695522_1 Von Willebrand factor A K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001181 267.0
TH1_k127_8695522_2 Acetyltransferase (GNAT) domain K22479 - - 0.00000000000000000000000000000000000000000000000000000000000001183 221.0
TH1_k127_8701714_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.266e-211 663.0
TH1_k127_8701714_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001518 257.0
TH1_k127_8701714_2 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.000000000000000000000000000000000000000000000000000000002284 203.0
TH1_k127_8701714_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000001091 194.0
TH1_k127_8701714_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000002426 138.0
TH1_k127_8701714_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000334 141.0
TH1_k127_8701714_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000003267 84.0
TH1_k127_8701714_7 Ribosomal protein L30 K02907 - - 0.000000000000000004149 85.0
TH1_k127_8701714_8 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000002497 70.0
TH1_k127_8711073_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 5.348e-244 774.0
TH1_k127_8711073_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 1.448e-205 653.0
TH1_k127_8711073_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007239 257.0
TH1_k127_8711073_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002062 255.0
TH1_k127_8711073_12 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000007241 242.0
TH1_k127_8711073_13 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000004165 237.0
TH1_k127_8711073_14 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000002866 222.0
TH1_k127_8711073_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000009443 215.0
TH1_k127_8711073_16 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000002599 202.0
TH1_k127_8711073_17 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000002547 188.0
TH1_k127_8711073_18 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000001918 146.0
TH1_k127_8711073_19 - - - - 0.0000004949 53.0
TH1_k127_8711073_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01740 - 2.5.1.48,2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 592.0
TH1_k127_8711073_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 514.0
TH1_k127_8711073_4 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 427.0
TH1_k127_8711073_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 401.0
TH1_k127_8711073_6 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 343.0
TH1_k127_8711073_7 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 334.0
TH1_k127_8711073_8 response regulator K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 309.0
TH1_k127_8711073_9 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002396 274.0
TH1_k127_8712783_0 PFAM Glycoside hydrolase 15-related - - - 1.982e-267 836.0
TH1_k127_8712783_1 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 8.436e-211 661.0
TH1_k127_8712783_10 esterase lipase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000003475 239.0
TH1_k127_8712783_11 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000002155 227.0
TH1_k127_8712783_12 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000002323 221.0
TH1_k127_8712783_13 Response regulator receiver K15012 - - 0.000000000000000000000000000000000000000000000000000000002442 209.0
TH1_k127_8712783_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 422.0
TH1_k127_8712783_3 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 400.0
TH1_k127_8712783_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 349.0
TH1_k127_8712783_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 297.0
TH1_k127_8712783_6 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001376 293.0
TH1_k127_8712783_7 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006113 275.0
TH1_k127_8712783_8 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002984 271.0
TH1_k127_8712783_9 Signal transduction histidine kinase K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000001241 252.0
TH1_k127_8733281_0 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 1.089e-292 917.0
TH1_k127_8733281_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003588 277.0
TH1_k127_8733281_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004459 258.0
TH1_k127_8733281_3 Lactoylglutathione lyase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001277 260.0
TH1_k127_8733281_4 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000001716 160.0
TH1_k127_8733281_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000000004658 126.0
TH1_k127_8733281_6 PFAM Uncharacterised protein family (UPF0150) - - - 0.00000000000000000000001184 102.0
TH1_k127_8759384_0 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 428.0
TH1_k127_8759384_1 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000005388 242.0
TH1_k127_8759384_2 arylsulfatase A K01130 - 3.1.6.1 0.000000000000000001048 89.0
TH1_k127_8759384_3 Protein of unknown function (DUF4239) - - - 0.00006949 51.0
TH1_k127_8772415_0 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 589.0
TH1_k127_8772415_1 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 332.0
TH1_k127_8772415_2 Belongs to the enoyl-CoA hydratase isomerase family K19640 - - 0.00000000000000000000000000000000000000000000000000000000001998 210.0
TH1_k127_8788295_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 592.0
TH1_k127_8788295_1 Extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 495.0
TH1_k127_8795032_0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 574.0
TH1_k127_8795032_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0055114 1.6.5.8 0.00000000000000000000000000000000000000000000000000001341 190.0
TH1_k127_8795032_2 PFAM CBS domain containing protein - - - 0.0000000000000000000000002481 111.0
TH1_k127_8833278_0 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 434.0
TH1_k127_8833278_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 412.0
TH1_k127_8833278_2 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 354.0
TH1_k127_8833278_3 Biotin-lipoyl like - - - 0.000000000000000000000000000002906 121.0
TH1_k127_8833690_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 2.409e-284 883.0
TH1_k127_8833690_1 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 5.133e-213 670.0
TH1_k127_8833690_10 Haem-degrading - - - 0.0000000000000000000000000000000000000001172 158.0
TH1_k127_8833690_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 575.0
TH1_k127_8833690_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 511.0
TH1_k127_8833690_4 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 325.0
TH1_k127_8833690_5 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 320.0
TH1_k127_8833690_6 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001272 247.0
TH1_k127_8833690_7 Trap-type c4-dicarboxylate transport system, small permease component - - - 0.000000000000000000000000000000000000000000000000000000001313 205.0
TH1_k127_8833690_8 PFAM Taurine catabolism dioxygenase TauD TfdA K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000002397 226.0
TH1_k127_8833690_9 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000004492 177.0
TH1_k127_8842678_0 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 459.0
TH1_k127_8842678_1 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 435.0
TH1_k127_8842678_10 - - - - 0.0000000000000000000000000000000000000000000000000000000004471 206.0
TH1_k127_8842678_11 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000002864 165.0
TH1_k127_8842678_12 PPIC-type PPIASE domain - - - 0.000000000000000000000000003719 128.0
TH1_k127_8842678_2 Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate K00966,K16881 GO:0000166,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0003983,GO:0005488,GO:0006011,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009225,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0051748,GO:0055086,GO:0070569,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 400.0
TH1_k127_8842678_3 Psort location OuterMembrane, score 9.92 K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 334.0
TH1_k127_8842678_4 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 351.0
TH1_k127_8842678_5 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 300.0
TH1_k127_8842678_6 eight transmembrane protein EpsH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001601 284.0
TH1_k127_8842678_7 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009209 282.0
TH1_k127_8842678_8 Glycosyltransferase family 25 (LPS biosynthesis protein) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007816 243.0
TH1_k127_8842678_9 Protein of unknown function (DUF3485) - - - 0.00000000000000000000000000000000000000000000000000000000001976 225.0
TH1_k127_8892708_0 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 8.389e-220 683.0
TH1_k127_8892708_1 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 502.0
TH1_k127_8892708_2 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000000000000000000000000000000000000006104 217.0
TH1_k127_8892708_3 DsrE/DsrF-like family K07236 - - 0.0000000000000000000000000000000000000000000000000000001895 199.0
TH1_k127_8892708_4 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000000000000000009644 190.0
TH1_k127_8892708_5 DsrH like protein K07237 - - 0.000000000000000000000000000001109 129.0
TH1_k127_8892708_6 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000114 119.0
TH1_k127_8960102_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 533.0
TH1_k127_8960102_1 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000003093 165.0
TH1_k127_9066883_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 9.735e-219 697.0
TH1_k127_9066883_1 GHMP kinase K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 533.0
TH1_k127_9080965_0 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 290.0
TH1_k127_9080965_1 PFAM Multiple antibiotic resistance (MarC)-related K05595 - - 0.00000000000000000000000000000000000000000000000000000000001533 219.0
TH1_k127_9080965_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000002134 91.0
TH1_k127_9129642_0 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 359.0
TH1_k127_9129642_1 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000000000634 209.0
TH1_k127_9129642_2 ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro Biopolymer transport protein ExbD TolR Pfam Biopolymer transport protein ExbD TolR no signal peptide K03559 - - 0.00000000000000000000000000000000000000000000000000308 188.0
TH1_k127_9129642_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000002116 173.0
TH1_k127_9129642_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000003699 122.0
TH1_k127_91423_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 544.0
TH1_k127_91423_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 531.0
TH1_k127_91423_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 309.0
TH1_k127_91423_3 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 284.0
TH1_k127_91423_4 Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism K02567 - - 0.000000000000000000000000000000000000000000000000000000000000001257 220.0
TH1_k127_91423_5 4Fe-4S binding domain K02572 - - 0.000000000000000000000000000000000000000002206 164.0
TH1_k127_91423_6 negative regulation of establishment of protein localization K02570 - - 0.00000000000121 78.0
TH1_k127_9175951_0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 384.0
TH1_k127_9175951_1 Xylose isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 368.0
TH1_k127_9175951_2 helix_turn_helix isocitrate lyase regulation K05818 - - 0.00000000000000000000000000000000000000000000000000000000000000009161 228.0
TH1_k127_9175951_3 Aldo/keto reductase family K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000001789 222.0
TH1_k127_9177023_0 Type II secretion system K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 372.0
TH1_k127_9177023_1 PFAM type II secretion system protein G K02456 - - 0.000000000000000000000000000000000000002539 154.0
TH1_k127_9177023_2 General secretion pathway protein H K02457 - - 0.00000000000000000000000000001063 130.0
TH1_k127_925018_0 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 503.0
TH1_k127_925018_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000006406 124.0
TH1_k127_925018_2 - - - - 0.0000008322 52.0
TH1_k127_9268382_0 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 322.0
TH1_k127_9268382_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002295 280.0
TH1_k127_9268382_2 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001194 272.0
TH1_k127_9365440_0 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 522.0
TH1_k127_9365440_1 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 462.0
TH1_k127_9365440_2 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 405.0
TH1_k127_9365440_3 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 310.0
TH1_k127_9365440_4 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000000000007599 229.0
TH1_k127_937148_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0 1056.0
TH1_k127_937148_1 AMP-binding enzyme C-terminal domain K02363 - 2.7.7.58,6.3.2.14 1.514e-198 627.0
TH1_k127_937148_2 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 469.0
TH1_k127_937148_3 FAD binding domain K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 426.0
TH1_k127_937148_4 - - - - 0.00000000000000000005419 100.0
TH1_k127_937148_5 - - - - 0.000000000000004778 85.0
TH1_k127_9635813_0 5-oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 0.0 1696.0
TH1_k127_9635813_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 560.0
TH1_k127_9635813_2 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 444.0
TH1_k127_9635813_3 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000000000000000000000000000000000000000000000000009405 197.0
TH1_k127_9661099_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.892e-226 714.0
TH1_k127_980698_0 carboxylase K01969 - 6.4.1.4 6.879e-284 879.0
TH1_k127_980698_1 poly(R)-hydroxyalkanoic acid synthase K03821 - - 4.969e-269 844.0
TH1_k127_980698_10 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 366.0
TH1_k127_980698_11 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 331.0
TH1_k127_980698_12 epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 294.0
TH1_k127_980698_13 Enoyl-CoA hydratase/isomerase K13766,K15312 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 298.0
TH1_k127_980698_14 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001077 293.0
TH1_k127_980698_15 cell septum assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005961 282.0
TH1_k127_980698_16 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000002654 238.0
TH1_k127_980698_17 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000787 233.0
TH1_k127_980698_18 Lysine exporter protein (Lyse ygga) - - - 0.00000000000000000000000000000000000000000000000000000000000000001051 230.0
TH1_k127_980698_19 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000002125 223.0
TH1_k127_980698_2 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 8.924e-246 777.0
TH1_k127_980698_20 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000007724 212.0
TH1_k127_980698_21 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000874 185.0
TH1_k127_980698_22 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000003436 195.0
TH1_k127_980698_23 transcriptional - - - 0.000000000000000000000000000000000007717 146.0
TH1_k127_980698_24 Glycine zipper 2TM domain - - - 0.00000000000000000000000000006319 123.0
TH1_k127_980698_3 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 5.431e-213 665.0
TH1_k127_980698_4 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 602.0
TH1_k127_980698_5 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 586.0
TH1_k127_980698_6 Soluble lytic murein transglycosylase L domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 493.0
TH1_k127_980698_7 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 457.0
TH1_k127_980698_8 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 444.0
TH1_k127_980698_9 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 402.0