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Overview

ID MAG03881
Name TH1_bin.60
Sample SMP0100
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family SM23-35
Genus JALHSV01
Species
Assembly information
Completeness (%) 66.83
Contamination (%) 2.18
GC content (%) 49.0
N50 (bp) 25,303
Genome size (bp) 1,385,918

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1304

Gene name Description KEGG GOs EC E-value Score Sequence
TH1_k127_1060535_0 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 323.0
TH1_k127_1060535_1 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 294.0
TH1_k127_1060535_2 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001229 264.0
TH1_k127_1060535_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000001096 213.0
TH1_k127_1232810_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 9.493e-273 864.0
TH1_k127_1232810_1 DNA polymerase K02347 - - 3.123e-235 739.0
TH1_k127_1232810_10 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 412.0
TH1_k127_1232810_11 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 408.0
TH1_k127_1232810_12 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 395.0
TH1_k127_1232810_13 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 387.0
TH1_k127_1232810_14 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 390.0
TH1_k127_1232810_15 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 381.0
TH1_k127_1232810_16 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 361.0
TH1_k127_1232810_17 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 347.0
TH1_k127_1232810_18 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 349.0
TH1_k127_1232810_19 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 338.0
TH1_k127_1232810_2 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 1.318e-196 620.0
TH1_k127_1232810_20 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 304.0
TH1_k127_1232810_21 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 301.0
TH1_k127_1232810_22 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 293.0
TH1_k127_1232810_23 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 298.0
TH1_k127_1232810_24 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003473 274.0
TH1_k127_1232810_25 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000005367 260.0
TH1_k127_1232810_26 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000004857 258.0
TH1_k127_1232810_27 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000006838 229.0
TH1_k127_1232810_28 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000001483 198.0
TH1_k127_1232810_29 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000001001 164.0
TH1_k127_1232810_3 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 599.0
TH1_k127_1232810_30 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000699 142.0
TH1_k127_1232810_31 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000012 130.0
TH1_k127_1232810_32 OstA-like protein K09774 - - 0.00000000000000000000000000000001775 132.0
TH1_k127_1232810_33 Thiamine-binding protein - - - 0.0000000000000000000000000000004601 126.0
TH1_k127_1232810_34 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000002826 128.0
TH1_k127_1232810_35 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000855 101.0
TH1_k127_1232810_36 Essential cell division protein K03589 - - 0.00000000000000000003926 100.0
TH1_k127_1232810_38 Stringent starvation protein B K09985 - - 0.0000006137 57.0
TH1_k127_1232810_39 Fimbrial assembly protein (PilN) K02663 - - 0.000002085 57.0
TH1_k127_1232810_4 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 546.0
TH1_k127_1232810_41 pilus assembly protein pilp K02665 - - 0.0001326 51.0
TH1_k127_1232810_42 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.0003393 50.0
TH1_k127_1232810_5 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 519.0
TH1_k127_1232810_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 519.0
TH1_k127_1232810_7 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009376 493.0
TH1_k127_1232810_8 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 478.0
TH1_k127_1232810_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 426.0
TH1_k127_1280030_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.998e-232 724.0
TH1_k127_1280030_1 Elongation factor SelB, winged helix K03833 - - 6.866e-218 692.0
TH1_k127_1280030_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 490.0
TH1_k127_1280030_11 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 461.0
TH1_k127_1280030_12 cysteine synthase A K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 442.0
TH1_k127_1280030_13 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 414.0
TH1_k127_1280030_14 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 379.0
TH1_k127_1280030_15 PFAM Protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 373.0
TH1_k127_1280030_16 membrane K09133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 346.0
TH1_k127_1280030_17 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 330.0
TH1_k127_1280030_18 zinc ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001422 259.0
TH1_k127_1280030_19 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000002333 233.0
TH1_k127_1280030_2 Bacterial protein of unknown function (DUF853) K06915 - - 2.161e-209 660.0
TH1_k127_1280030_20 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000005407 218.0
TH1_k127_1280030_21 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000002594 197.0
TH1_k127_1280030_22 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000000006798 197.0
TH1_k127_1280030_23 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000213 194.0
TH1_k127_1280030_24 protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000001757 184.0
TH1_k127_1280030_25 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000001201 182.0
TH1_k127_1280030_26 Histidine kinase - - - 0.0000000000000000000000000000000000000000004963 171.0
TH1_k127_1280030_27 competence protein - - - 0.0000000000000000000000000000000000000009296 157.0
TH1_k127_1280030_28 nucleotide metabolic process - - - 0.0000000000000000000000000000000000001505 150.0
TH1_k127_1280030_29 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000003331 145.0
TH1_k127_1280030_3 Aminotransferase class-III K01845 - 5.4.3.8 3.69e-200 631.0
TH1_k127_1280030_30 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000001136 135.0
TH1_k127_1280030_31 SMART serine threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase K01090 - 3.1.3.16 0.00000000000000000000000001321 119.0
TH1_k127_1280030_32 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000003881 117.0
TH1_k127_1280030_33 - - - - 0.0000000000000000185 90.0
TH1_k127_1280030_34 Protein of unknown function (DUF2845) - - - 0.0000000000000001362 84.0
TH1_k127_1280030_35 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000001889 71.0
TH1_k127_1280030_36 Tetratricopeptide repeat-like domain - - - 0.0000000001626 70.0
TH1_k127_1280030_37 One HIP oligomer binds the ATPase domains of at least two Hsc70 molecules dependent on activation of the Hsc70 ATPase by Hsp40. Stabilizes the ADP state of Hsc70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of Hsc70 with various target proteins (By similarity) K09560 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030544,GO:0030554,GO:0030674,GO:0031072,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060090,GO:0061077,GO:0061083,GO:0061084,GO:0065003,GO:0065007,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1903332,GO:1903333 - 0.000000006053 64.0
TH1_k127_1280030_38 PilZ domain - - - 0.00006468 51.0
TH1_k127_1280030_39 hmm pf04305 - - - 0.0002309 48.0
TH1_k127_1280030_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 605.0
TH1_k127_1280030_5 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 573.0
TH1_k127_1280030_6 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 553.0
TH1_k127_1280030_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 531.0
TH1_k127_1280030_8 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 508.0
TH1_k127_1280030_9 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 495.0
TH1_k127_1553577_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.074e-244 760.0
TH1_k127_1553577_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 421.0
TH1_k127_1553577_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 392.0
TH1_k127_1553577_3 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 301.0
TH1_k127_1553577_4 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007894 272.0
TH1_k127_1553577_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000003661 264.0
TH1_k127_1553577_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000001995 259.0
TH1_k127_1553577_7 Nitrogen regulatory protein P-II K04751,K04752 - - 0.00000000000000000000000000000000000000001299 160.0
TH1_k127_1553577_8 - - - - 0.0000000000000000002211 94.0
TH1_k127_1553577_9 lipopolysaccharide transmembrane transporter activity K03303,K07058 - - 0.00000000008992 72.0
TH1_k127_1596116_0 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 288.0
TH1_k127_1596116_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000219 262.0
TH1_k127_1596116_2 DGC domain - - - 0.000000000000000000000000000000000000000000000000000378 190.0
TH1_k127_1596116_3 amine dehydrogenase activity - - - 0.000000008659 66.0
TH1_k127_1596116_4 leucine-zipper of insertion element IS481 K00986,K07497 - 2.7.7.49 0.00000004991 64.0
TH1_k127_1596116_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000007855 53.0
TH1_k127_1596116_6 COG2801 Transposase and inactivated derivatives - - - 0.000002145 53.0
TH1_k127_1596116_7 protein targeting - - - 0.000002366 57.0
TH1_k127_1596116_8 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000004329 51.0
TH1_k127_1654947_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.339e-253 794.0
TH1_k127_1654947_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 464.0
TH1_k127_1654947_10 CAAX protease self-immunity - - - 0.000000009133 64.0
TH1_k127_1654947_2 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 438.0
TH1_k127_1654947_3 Subtilase family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 344.0
TH1_k127_1654947_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 296.0
TH1_k127_1654947_5 PBS lyase K22221 - - 0.0000000000000000000000000000000000000000000001811 187.0
TH1_k127_1654947_6 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000956 167.0
TH1_k127_1654947_7 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000004338 117.0
TH1_k127_1654947_8 - - - - 0.0000000000000000002223 97.0
TH1_k127_1857477_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1209.0
TH1_k127_1857477_1 Transport of potassium into the cell K03549 - - 2.078e-241 760.0
TH1_k127_1857477_10 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 339.0
TH1_k127_1857477_11 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 317.0
TH1_k127_1857477_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 301.0
TH1_k127_1857477_13 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 298.0
TH1_k127_1857477_14 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 293.0
TH1_k127_1857477_15 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 286.0
TH1_k127_1857477_16 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 292.0
TH1_k127_1857477_17 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001448 278.0
TH1_k127_1857477_18 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001942 284.0
TH1_k127_1857477_19 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002846 288.0
TH1_k127_1857477_2 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 577.0
TH1_k127_1857477_20 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001018 280.0
TH1_k127_1857477_21 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007141 263.0
TH1_k127_1857477_22 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000004164 258.0
TH1_k127_1857477_23 Oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002073 273.0
TH1_k127_1857477_24 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000001744 241.0
TH1_k127_1857477_25 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000002358 215.0
TH1_k127_1857477_26 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000001093 176.0
TH1_k127_1857477_27 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000000000000000000000000875 168.0
TH1_k127_1857477_29 Bacterial regulatory protein, Fis family K02481 - - 0.00000000000000000000000000000000004074 142.0
TH1_k127_1857477_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 550.0
TH1_k127_1857477_30 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000008448 123.0
TH1_k127_1857477_31 - - - - 0.000000000000000000005536 96.0
TH1_k127_1857477_32 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000001357 88.0
TH1_k127_1857477_33 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000006228 79.0
TH1_k127_1857477_34 - - - - 0.00000000000002104 74.0
TH1_k127_1857477_35 cytochrome C peroxidase - - - 0.00000000000002628 76.0
TH1_k127_1857477_36 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000846 56.0
TH1_k127_1857477_37 Psort location Extracellular, score K21471 - - 0.0001485 45.0
TH1_k127_1857477_4 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 518.0
TH1_k127_1857477_5 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 509.0
TH1_k127_1857477_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 506.0
TH1_k127_1857477_7 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 490.0
TH1_k127_1857477_8 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 456.0
TH1_k127_1857477_9 cysteine-tRNA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 434.0
TH1_k127_1865990_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1094.0
TH1_k127_1865990_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1072.0
TH1_k127_1865990_10 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000001335 254.0
TH1_k127_1865990_11 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000001634 241.0
TH1_k127_1865990_12 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000167 233.0
TH1_k127_1865990_13 ATP cone domain - - - 0.000000000000000000000000000000000000000000000000000000000000001349 228.0
TH1_k127_1865990_14 Pfam:TPM K08988 - - 0.0000000000000000000000000000000000000000000000000000000003235 208.0
TH1_k127_1865990_15 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000006075 203.0
TH1_k127_1865990_16 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000000000000005403 177.0
TH1_k127_1865990_17 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000003989 166.0
TH1_k127_1865990_18 molybdopterin synthase activity K03635,K03752 - 2.7.7.77,2.8.1.12 0.000000000000000000000000000000000000006685 148.0
TH1_k127_1865990_19 Thioredoxin-like - - - 0.0000000000000000000000000000000004633 137.0
TH1_k127_1865990_2 1,4-alpha-glucan branching enzyme activity K00700,K01187,K01236,K17734 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,3.2.1.141,3.2.1.20 1e-322 1002.0
TH1_k127_1865990_20 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000002866 132.0
TH1_k127_1865990_21 NusG domain II - - - 0.000000000000002609 80.0
TH1_k127_1865990_22 - - - - 0.00000000000002762 75.0
TH1_k127_1865990_23 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000002865 70.0
TH1_k127_1865990_25 COG NOG19146 non supervised orthologous group - - - 0.0000817 47.0
TH1_k127_1865990_26 Protein of unknown function (DUF1573) - - - 0.0001454 46.0
TH1_k127_1865990_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 454.0
TH1_k127_1865990_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 376.0
TH1_k127_1865990_5 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 366.0
TH1_k127_1865990_6 MoeA C-terminal region (domain IV) K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 313.0
TH1_k127_1865990_7 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 289.0
TH1_k127_1865990_8 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003202 282.0
TH1_k127_1865990_9 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001686 269.0
TH1_k127_2449240_0 Domain of unknown function (DUF4139) - - - 7.45e-196 622.0
TH1_k127_2449240_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 302.0
TH1_k127_2449240_2 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000003345 221.0
TH1_k127_2710463_0 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 419.0
TH1_k127_2710463_2 PFAM RES domain - - - 0.0000000000000000000000000000000000000000001313 163.0
TH1_k127_2710463_4 - - - - 0.0000000000000000000396 92.0
TH1_k127_2710463_5 alginic acid biosynthetic process - - - 0.00000000000000000009337 103.0
TH1_k127_2710463_6 Uncharacterized protein conserved in bacteria N-term (DUF3322) - - - 0.0000000000000000009324 87.0
TH1_k127_2710463_7 Protein of unknown function (DUF2384) - - - 0.00000000000000000121 91.0
TH1_k127_2710463_8 nuclease activity K06218 - - 0.000000000000001781 79.0
TH1_k127_2710463_9 HNH nucleases - - - 0.0000000006938 64.0
TH1_k127_2862868_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 2.703e-217 683.0
TH1_k127_2862868_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003142 285.0
TH1_k127_2862868_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000348 202.0
TH1_k127_2862868_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000001436 58.0
TH1_k127_2863433_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 590.0
TH1_k127_2863433_1 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005261 281.0
TH1_k127_2863433_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000001403 194.0
TH1_k127_2967113_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 380.0
TH1_k127_2967113_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 355.0
TH1_k127_2967113_2 - - - - 0.000000000000000000000000000000008455 133.0
TH1_k127_2967113_3 - - - - 0.0000000000000000000000000007405 114.0
TH1_k127_2967113_4 - - - - 0.00000000000000000000000001027 111.0
TH1_k127_2967113_5 - - - - 0.00000000006166 65.0
TH1_k127_2983109_0 calcium, potassium:sodium antiporter activity K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 363.0
TH1_k127_2983109_1 AMP binding - - - 0.000000000000000000000000000000000000000006559 167.0
TH1_k127_2983109_2 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000001378 109.0
TH1_k127_2994609_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.881e-240 754.0
TH1_k127_2994609_1 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 368.0
TH1_k127_2994609_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 309.0
TH1_k127_2994609_3 metal-dependent enzyme K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000004009 235.0
TH1_k127_2994609_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000003697 224.0
TH1_k127_2994609_5 Dihydroorotate dehydrogenase electron transfer subunit K02823 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0042602,GO:0052875,GO:0055114 - 0.0000000000000000000000000000000000000000000000001867 185.0
TH1_k127_2994609_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000003775 177.0
TH1_k127_2994609_7 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000234 110.0
TH1_k127_2994609_8 Protein of unknown function (DUF1214) - - - 0.00000000000000000001152 93.0
TH1_k127_2994609_9 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000002659 62.0
TH1_k127_3044796_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 3.452e-234 742.0
TH1_k127_3044796_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.102e-198 629.0
TH1_k127_3044796_10 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 356.0
TH1_k127_3044796_11 NADPH-dependent FMN reductase K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 331.0
TH1_k127_3044796_12 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 315.0
TH1_k127_3044796_13 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001819 285.0
TH1_k127_3044796_14 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003544 274.0
TH1_k127_3044796_15 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003707 274.0
TH1_k127_3044796_16 Metal-dependent phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004183 267.0
TH1_k127_3044796_17 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002774 260.0
TH1_k127_3044796_18 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000002285 233.0
TH1_k127_3044796_19 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000001409 234.0
TH1_k127_3044796_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 608.0
TH1_k127_3044796_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000005922 226.0
TH1_k127_3044796_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000001313 209.0
TH1_k127_3044796_22 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000000000003085 210.0
TH1_k127_3044796_23 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000003349 198.0
TH1_k127_3044796_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000001798 175.0
TH1_k127_3044796_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000008003 142.0
TH1_k127_3044796_26 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000707 131.0
TH1_k127_3044796_27 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000001474 119.0
TH1_k127_3044796_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000008708 116.0
TH1_k127_3044796_29 RelB antitoxin K07473 - - 0.000000000000000000000000005329 112.0
TH1_k127_3044796_3 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 518.0
TH1_k127_3044796_30 TIGRFAM addiction module toxin component, YafQ family K19157 - - 0.0000000000000000000000001814 108.0
TH1_k127_3044796_31 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000007609 63.0
TH1_k127_3044796_33 Lipid A biosynthesis K02517 - 2.3.1.241 0.000001975 59.0
TH1_k127_3044796_34 HMGL-like - - - 0.000006916 54.0
TH1_k127_3044796_36 Putative prokaryotic signal transducing protein - - - 0.000946 44.0
TH1_k127_3044796_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 521.0
TH1_k127_3044796_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 467.0
TH1_k127_3044796_6 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 448.0
TH1_k127_3044796_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 447.0
TH1_k127_3044796_8 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 402.0
TH1_k127_3044796_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 366.0
TH1_k127_305491_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.425e-199 629.0
TH1_k127_305491_1 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 593.0
TH1_k127_305491_10 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 311.0
TH1_k127_305491_11 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001898 278.0
TH1_k127_305491_12 amino acid ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003488 279.0
TH1_k127_305491_13 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005147 274.0
TH1_k127_305491_14 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002334 272.0
TH1_k127_305491_15 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000445 263.0
TH1_k127_305491_16 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000008598 244.0
TH1_k127_305491_17 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000007478 237.0
TH1_k127_305491_18 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000003899 213.0
TH1_k127_305491_19 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000001493 207.0
TH1_k127_305491_2 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 560.0
TH1_k127_305491_20 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000004157 171.0
TH1_k127_305491_21 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000252 160.0
TH1_k127_305491_22 ferredoxin-thioredoxin reductase activity - - - 0.0000000000000000000000000000000000000001242 152.0
TH1_k127_305491_23 methyltransferase - - - 0.0000000000000000000000000000000000004067 147.0
TH1_k127_305491_24 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000005802 143.0
TH1_k127_305491_25 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.00000000000000000000000000002665 119.0
TH1_k127_305491_26 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000003489 118.0
TH1_k127_305491_28 - - - - 0.0000000000000000000001941 102.0
TH1_k127_305491_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 547.0
TH1_k127_305491_30 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000001677 87.0
TH1_k127_305491_31 Evidence 5 No homology to any previously reported sequences K03765 - - 0.000000000000003683 89.0
TH1_k127_305491_32 - - - - 0.0000003963 57.0
TH1_k127_305491_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 452.0
TH1_k127_305491_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 411.0
TH1_k127_305491_6 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 415.0
TH1_k127_305491_7 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 371.0
TH1_k127_305491_8 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 327.0
TH1_k127_305491_9 PFAM Bacterial protein of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 308.0
TH1_k127_3096361_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 6.756e-240 753.0
TH1_k127_3096361_1 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 1.876e-199 627.0
TH1_k127_3096361_10 radical SAM K06871 - - 0.00000000000000000000000000000000000000001656 166.0
TH1_k127_3096361_11 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000007906 135.0
TH1_k127_3096361_12 electron transfer activity K05337,K17247 - - 0.000000000000000000009948 92.0
TH1_k127_3096361_13 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000562 84.0
TH1_k127_3096361_14 radical SAM domain protein - - - 0.00007506 50.0
TH1_k127_3096361_2 sister chromatid segregation - - - 3.099e-199 632.0
TH1_k127_3096361_3 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 358.0
TH1_k127_3096361_4 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 350.0
TH1_k127_3096361_5 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 331.0
TH1_k127_3096361_6 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005488 243.0
TH1_k127_3096361_7 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001031 243.0
TH1_k127_3096361_8 General secretory system II, protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000008447 169.0
TH1_k127_3096361_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000002386 169.0
TH1_k127_3178613_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 573.0
TH1_k127_3178613_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 432.0
TH1_k127_3178613_10 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000002187 195.0
TH1_k127_3178613_11 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000006345 172.0
TH1_k127_3178613_12 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000007141 139.0
TH1_k127_3178613_13 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001499 89.0
TH1_k127_3178613_2 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 436.0
TH1_k127_3178613_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 409.0
TH1_k127_3178613_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 397.0
TH1_k127_3178613_5 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 363.0
TH1_k127_3178613_6 Nitrite and sulphite reductase 4Fe-4S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 304.0
TH1_k127_3178613_7 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 298.0
TH1_k127_3178613_8 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005789 250.0
TH1_k127_3178613_9 - - - - 0.00000000000000000000000000000000000000000000000000000000006427 210.0
TH1_k127_3195070_0 Surface antigen K07277 - - 1.687e-258 818.0
TH1_k127_3195070_1 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 1.166e-226 709.0
TH1_k127_3195070_10 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002545 263.0
TH1_k127_3195070_11 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002613 255.0
TH1_k127_3195070_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000003393 209.0
TH1_k127_3195070_13 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000317 176.0
TH1_k127_3195070_14 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000000000000000000000005519 178.0
TH1_k127_3195070_15 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.0000000000000000000000000000000000000000000001647 169.0
TH1_k127_3195070_16 metal cluster binding K06940 - - 0.0000000000000000000000000000000000000000046 163.0
TH1_k127_3195070_17 lyase activity - - - 0.000000000000000000000000000000000000006048 154.0
TH1_k127_3195070_18 Lysin motif - - - 0.00000000000000000000000000000006585 137.0
TH1_k127_3195070_19 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.000000000000000000000000000008974 125.0
TH1_k127_3195070_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 3.724e-204 646.0
TH1_k127_3195070_20 Dissimilatory sulfite reductase D (DsrD) - - - 0.0000000000000000001933 90.0
TH1_k127_3195070_21 Regulatory protein, FmdB family - - - 0.000000000000000004005 86.0
TH1_k127_3195070_3 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 605.0
TH1_k127_3195070_4 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 496.0
TH1_k127_3195070_5 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 445.0
TH1_k127_3195070_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 394.0
TH1_k127_3195070_7 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 385.0
TH1_k127_3195070_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 379.0
TH1_k127_3195070_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005318 258.0
TH1_k127_3255600_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1140.0
TH1_k127_3255600_1 PFAM Integrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 312.0
TH1_k127_3255600_2 phosphorelay signal transduction system - - - 0.000000000000000000003963 102.0
TH1_k127_3280867_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 441.0
TH1_k127_3280867_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 368.0
TH1_k127_3280867_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000007165 63.0
TH1_k127_3280867_2 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 301.0
TH1_k127_3280867_3 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001092 283.0
TH1_k127_3280867_4 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003707 264.0
TH1_k127_3280867_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000001472 133.0
TH1_k127_3280867_6 denitrification pathway - - - 0.0000000000000000000000000001649 121.0
TH1_k127_3280867_7 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000007402 81.0
TH1_k127_3280867_8 - - - - 0.000000000001844 81.0
TH1_k127_3280867_9 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.0000000003654 71.0
TH1_k127_3410520_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 541.0
TH1_k127_3410520_1 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 478.0
TH1_k127_3410520_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 376.0
TH1_k127_3410520_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002911 245.0
TH1_k127_3410520_4 Protein of unknown function DUF262 - - - 0.000000000000000000000000000000000000000002402 169.0
TH1_k127_3410520_5 Protein of unknown function (DUF4019) - - - 0.0000000000000000000000000000000000000009486 152.0
TH1_k127_3410520_6 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001449 106.0
TH1_k127_3410520_7 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000002332 61.0
TH1_k127_3701345_0 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 511.0
TH1_k127_3701345_1 - - - - 0.00000000000000000000000000000000000000000000002641 173.0
TH1_k127_3701345_2 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000000000629 171.0
TH1_k127_3701345_3 DNA RNA non-specific endonuclease K01173 - - 0.000000000000000000000000006204 116.0
TH1_k127_3701345_4 Glycine-zipper domain - - - 0.00000000000000000000000001655 111.0
TH1_k127_3701345_5 - - - - 0.00000000000000000000000003907 115.0
TH1_k127_3701345_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000009952 114.0
TH1_k127_3701345_7 Staphylococcal nuclease homologues - - - 0.00000000000000001013 87.0
TH1_k127_3840744_0 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 381.0
TH1_k127_3840744_1 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 339.0
TH1_k127_3840744_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 293.0
TH1_k127_3840744_3 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000002258 253.0
TH1_k127_3840744_4 cobalamin synthesis protein, P47K - - - 0.00000000000000000000000000000000000000000001064 174.0
TH1_k127_3840744_5 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000000000000000101 145.0
TH1_k127_3840744_6 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000002064 136.0
TH1_k127_3840744_7 Peptidase family M48 - - - 0.00000000167 69.0
TH1_k127_4125137_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1098.0
TH1_k127_4125137_1 Conserved carboxylase domain K01958 - 6.4.1.1 0.0 1088.0
TH1_k127_4125137_10 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 564.0
TH1_k127_4125137_11 Nitronate monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 503.0
TH1_k127_4125137_12 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 508.0
TH1_k127_4125137_13 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 479.0
TH1_k127_4125137_14 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 436.0
TH1_k127_4125137_15 Dehydrogenase E1 component K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 420.0
TH1_k127_4125137_16 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 400.0
TH1_k127_4125137_17 radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 391.0
TH1_k127_4125137_18 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 395.0
TH1_k127_4125137_19 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 387.0
TH1_k127_4125137_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1037.0
TH1_k127_4125137_20 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 379.0
TH1_k127_4125137_21 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 379.0
TH1_k127_4125137_22 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 359.0
TH1_k127_4125137_23 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 365.0
TH1_k127_4125137_24 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 366.0
TH1_k127_4125137_25 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 343.0
TH1_k127_4125137_26 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 344.0
TH1_k127_4125137_27 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 325.0
TH1_k127_4125137_28 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 313.0
TH1_k127_4125137_29 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 285.0
TH1_k127_4125137_3 carbon starvation protein CstA K06200 - - 9.796e-301 933.0
TH1_k127_4125137_30 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003915 293.0
TH1_k127_4125137_31 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003293 285.0
TH1_k127_4125137_32 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008723 273.0
TH1_k127_4125137_33 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007309 275.0
TH1_k127_4125137_34 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001433 258.0
TH1_k127_4125137_35 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000001651 253.0
TH1_k127_4125137_36 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000004774 269.0
TH1_k127_4125137_37 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000004762 243.0
TH1_k127_4125137_38 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007625 242.0
TH1_k127_4125137_39 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000002259 242.0
TH1_k127_4125137_4 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.776e-286 890.0
TH1_k127_4125137_40 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000001437 242.0
TH1_k127_4125137_41 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000463 223.0
TH1_k127_4125137_42 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000000000000000005362 220.0
TH1_k127_4125137_43 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000166 220.0
TH1_k127_4125137_44 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000002365 220.0
TH1_k127_4125137_45 Histidine kinase K02668,K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000002149 226.0
TH1_k127_4125137_46 nucleotide catabolic process - - - 0.00000000000000000000000000000000000000000000000000004414 191.0
TH1_k127_4125137_47 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000006024 189.0
TH1_k127_4125137_48 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000001628 193.0
TH1_k127_4125137_49 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000003791 179.0
TH1_k127_4125137_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 1.967e-284 900.0
TH1_k127_4125137_50 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000000000003077 171.0
TH1_k127_4125137_51 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000000000000000000000000000000000000000005925 169.0
TH1_k127_4125137_52 Response regulator, receiver K11443 - - 0.00000000000000000000000000000000000000000001218 165.0
TH1_k127_4125137_53 - - - - 0.00000000000000000000000000000000000000000002749 168.0
TH1_k127_4125137_54 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000007615 168.0
TH1_k127_4125137_55 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000005974 160.0
TH1_k127_4125137_56 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000001098 154.0
TH1_k127_4125137_57 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.00000000000000000000000000000000004884 145.0
TH1_k127_4125137_58 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.0000000000000000000000000000002692 129.0
TH1_k127_4125137_59 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000001273 126.0
TH1_k127_4125137_6 acetyl-CoA carboxylase, biotin carboxylase K01965 - 6.4.1.3 6.874e-242 754.0
TH1_k127_4125137_60 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000004901 128.0
TH1_k127_4125137_61 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000005898 119.0
TH1_k127_4125137_62 - - - - 0.00000000000000000000000006644 116.0
TH1_k127_4125137_63 Predicted RNA-binding protein - - - 0.000000000000000000001156 96.0
TH1_k127_4125137_64 Membrane - - - 0.0000000000006282 77.0
TH1_k127_4125137_65 Tetratricopeptide repeats - - - 0.00000000004932 69.0
TH1_k127_4125137_66 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000001995 74.0
TH1_k127_4125137_69 Universal stress protein family - - - 0.000006704 49.0
TH1_k127_4125137_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 7.748e-233 734.0
TH1_k127_4125137_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 7.514e-213 667.0
TH1_k127_4125137_9 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 6.492e-199 641.0
TH1_k127_4253297_0 Aconitase C-terminal domain K01681 - 4.2.1.3 1.301e-292 912.0
TH1_k127_4253297_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.21e-257 797.0
TH1_k127_4253297_10 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000541 219.0
TH1_k127_4253297_11 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000005226 164.0
TH1_k127_4253297_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000004431 160.0
TH1_k127_4253297_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000001814 156.0
TH1_k127_4253297_14 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000000000001778 136.0
TH1_k127_4253297_15 Protein of unknown function (DUF3187) - - - 0.00000000000000000000002172 110.0
TH1_k127_4253297_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.405e-250 780.0
TH1_k127_4253297_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 559.0
TH1_k127_4253297_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 455.0
TH1_k127_4253297_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 404.0
TH1_k127_4253297_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 360.0
TH1_k127_4253297_7 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 335.0
TH1_k127_4253297_8 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 328.0
TH1_k127_4253297_9 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.000000000000000000000000000000000000000000000000000000000000000001595 234.0
TH1_k127_4264622_0 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 562.0
TH1_k127_4264622_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 341.0
TH1_k127_4264622_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007639 268.0
TH1_k127_4264622_3 - - - - 0.000000000000000000000000000000000000000000000000003665 185.0
TH1_k127_4264622_4 SNARE associated Golgi protein - - - 0.0000000000000000000000009538 111.0
TH1_k127_4264622_5 4Fe-4S binding domain - - - 0.00000000000000000000002276 100.0
TH1_k127_4264622_6 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.00000000000000000758 87.0
TH1_k127_4357908_0 Dehydratase family K01687 - 4.2.1.9 1.099e-257 807.0
TH1_k127_4357908_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 458.0
TH1_k127_4357908_2 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 430.0
TH1_k127_4357908_3 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 323.0
TH1_k127_4357908_4 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000002228 225.0
TH1_k127_4357908_5 retrograde transport, endosome to Golgi K07095 - - 0.00000000000000000000000000000000000000000000007019 173.0
TH1_k127_4357908_6 MarC family integral membrane protein - - - 0.00000000000000000000000000000000000000000002263 168.0
TH1_k127_4357908_7 PFAM Class I peptide chain release factor - - - 0.0000000000000000000000000000000000000005587 151.0
TH1_k127_4357908_8 PFAM Smr protein MutS2 - - - 0.0000000000000000002972 89.0
TH1_k127_4357908_9 Protein of unknown function (DUF465) K09794 - - 0.00000000000000002697 84.0
TH1_k127_4441065_0 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.0 1103.0
TH1_k127_4441065_1 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 601.0
TH1_k127_4441065_10 Cysteine rich repeat - - - 0.000000000000000000000000000000000000000000006187 166.0
TH1_k127_4441065_11 Protein of unknown function DUF126 K09123,K09128 - - 0.000000000000000000000000000000000000004397 150.0
TH1_k127_4441065_12 - - - - 0.0000000000000000000000000000002156 126.0
TH1_k127_4441065_13 addiction module killer protein - - - 0.000000000000000000000000005997 111.0
TH1_k127_4441065_14 nuclease activity K06218 - - 0.00000000000000000000000001846 110.0
TH1_k127_4441065_15 Helix-turn-helix domain - - - 0.000000000000000000000003961 103.0
TH1_k127_4441065_16 - - - - 0.000000000000000005008 85.0
TH1_k127_4441065_17 Virulence protein RhuM family - - - 0.0000001749 55.0
TH1_k127_4441065_18 - - - - 0.0000008127 56.0
TH1_k127_4441065_19 - - - - 0.0001924 46.0
TH1_k127_4441065_2 surface antigen variable number repeat protein K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 533.0
TH1_k127_4441065_3 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 376.0
TH1_k127_4441065_4 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 302.0
TH1_k127_4441065_5 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000000000000000000003392 230.0
TH1_k127_4441065_6 Zeta toxin - - - 0.000000000000000000000000000000000000000000000000000000000000000004648 230.0
TH1_k127_4441065_7 MltA-interacting protein MipA K07274 - - 0.0000000000000000000000000000000000000000000000000000008338 202.0
TH1_k127_4441065_8 - K07275 - - 0.000000000000000000000000000000000000000000000000000001226 198.0
TH1_k127_4441065_9 Transglutaminase-like - - - 0.00000000000000000000000000000000000000000000000003999 182.0
TH1_k127_4573889_0 COG0058 Glucan phosphorylase - - - 1.13e-255 799.0
TH1_k127_4573889_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 2.251e-202 638.0
TH1_k127_4573889_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 346.0
TH1_k127_4573889_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 334.0
TH1_k127_4573889_4 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 290.0
TH1_k127_4573889_5 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000004074 216.0
TH1_k127_4573889_7 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000000000001479 178.0
TH1_k127_4573889_9 protein secretion K03116,K03117 - - 0.0000000000001241 75.0
TH1_k127_4580185_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 2.231e-260 814.0
TH1_k127_4580185_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.091e-209 659.0
TH1_k127_4580185_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000004744 262.0
TH1_k127_4580185_11 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000009219 257.0
TH1_k127_4580185_12 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000002238 233.0
TH1_k127_4580185_13 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000004334 223.0
TH1_k127_4580185_14 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000003113 207.0
TH1_k127_4580185_15 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000227 197.0
TH1_k127_4580185_16 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000001583 161.0
TH1_k127_4580185_17 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000005767 138.0
TH1_k127_4580185_18 - - - - 0.00000000000000000000001024 104.0
TH1_k127_4580185_19 Type II secretion system protein B K02451 - - 0.0000000000000000000003555 106.0
TH1_k127_4580185_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 5.758e-199 624.0
TH1_k127_4580185_21 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000004739 80.0
TH1_k127_4580185_22 exonuclease activity K16899 - 3.6.4.12 0.000000000003304 79.0
TH1_k127_4580185_3 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 509.0
TH1_k127_4580185_4 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 501.0
TH1_k127_4580185_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 486.0
TH1_k127_4580185_6 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 436.0
TH1_k127_4580185_7 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 340.0
TH1_k127_4580185_8 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 323.0
TH1_k127_4580185_9 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 318.0
TH1_k127_4621053_0 Glycosyl hydrolase family 57 - - - 2.235e-225 719.0
TH1_k127_4621053_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 467.0
TH1_k127_4621053_10 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000004402 90.0
TH1_k127_4621053_11 cell cycle K05589,K12065,K13052 - - 0.00000000000002644 76.0
TH1_k127_4621053_14 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0001284 54.0
TH1_k127_4621053_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 428.0
TH1_k127_4621053_3 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 398.0
TH1_k127_4621053_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 368.0
TH1_k127_4621053_5 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000002055 263.0
TH1_k127_4621053_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000001128 180.0
TH1_k127_4621053_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000003131 161.0
TH1_k127_4621053_8 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000003759 151.0
TH1_k127_4621053_9 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000331 125.0
TH1_k127_481988_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1752.0
TH1_k127_481988_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.36e-322 1007.0
TH1_k127_481988_10 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 490.0
TH1_k127_481988_11 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 472.0
TH1_k127_481988_12 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 379.0
TH1_k127_481988_13 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 374.0
TH1_k127_481988_14 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 352.0
TH1_k127_481988_15 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 352.0
TH1_k127_481988_16 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 346.0
TH1_k127_481988_17 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 345.0
TH1_k127_481988_18 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 325.0
TH1_k127_481988_19 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 319.0
TH1_k127_481988_2 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 2.573e-312 963.0
TH1_k127_481988_20 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 319.0
TH1_k127_481988_21 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 317.0
TH1_k127_481988_22 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 315.0
TH1_k127_481988_23 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 302.0
TH1_k127_481988_24 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 297.0
TH1_k127_481988_25 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001666 284.0
TH1_k127_481988_26 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001914 281.0
TH1_k127_481988_27 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001458 275.0
TH1_k127_481988_28 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000006574 231.0
TH1_k127_481988_29 DnaJ molecular chaperone homology domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000003311 227.0
TH1_k127_481988_3 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 4.231e-251 786.0
TH1_k127_481988_30 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000004862 220.0
TH1_k127_481988_31 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.00000000000000000000000000000000000000000000000000003041 194.0
TH1_k127_481988_32 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000694 190.0
TH1_k127_481988_33 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000177 179.0
TH1_k127_481988_34 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000001292 170.0
TH1_k127_481988_35 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000001617 160.0
TH1_k127_481988_36 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.000000000000000000000000000000000000000002819 159.0
TH1_k127_481988_37 - - - - 0.000000000000000000000000000000000000003173 153.0
TH1_k127_481988_38 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000103 151.0
TH1_k127_481988_39 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000009544 141.0
TH1_k127_481988_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.591e-225 710.0
TH1_k127_481988_40 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000000006116 136.0
TH1_k127_481988_41 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000004966 129.0
TH1_k127_481988_42 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000007733 129.0
TH1_k127_481988_43 - - - - 0.00000000000000000000000000001211 122.0
TH1_k127_481988_44 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000000000004442 122.0
TH1_k127_481988_45 SMART Cold shock protein K03704 - - 0.0000000000000000000000000001136 116.0
TH1_k127_481988_47 Domain of unknown function (DUF4870) K09940 - - 0.000000000000000000000001511 109.0
TH1_k127_481988_48 iron-sulfur cluster assembly - - - 0.00000000000000000000004769 100.0
TH1_k127_481988_49 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.0000000000000000000002658 102.0
TH1_k127_481988_5 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.155e-220 694.0
TH1_k127_481988_50 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000003665 72.0
TH1_k127_481988_51 regulation of DNA repair K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000001167 72.0
TH1_k127_481988_52 cobalt transport protein K16785 - - 0.00000002261 63.0
TH1_k127_481988_53 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000001567 59.0
TH1_k127_481988_6 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 579.0
TH1_k127_481988_7 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 537.0
TH1_k127_481988_8 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 515.0
TH1_k127_481988_9 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 486.0
TH1_k127_4827484_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 551.0
TH1_k127_4827484_1 sugar transferase K00996 - 2.7.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005468 425.0
TH1_k127_4827484_2 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 366.0
TH1_k127_4827484_3 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000005067 188.0
TH1_k127_4827484_4 PFAM Fimbrial assembly K02461 - - 0.000000000000000000000000007202 126.0
TH1_k127_4827484_5 PFAM Glycosyl transferase family 2 K12992 - - 0.000000000000000000000006742 103.0
TH1_k127_4827484_6 Type II secretion system (T2SS), protein M subtype b - - - 0.00000000001731 72.0
TH1_k127_4827484_7 pilus assembly protein PilW K02459,K02672 - - 0.000000002519 67.0
TH1_k127_4827484_8 Prokaryotic N-terminal methylation motif K02458 - - 0.000001769 57.0
TH1_k127_4827484_9 Prokaryotic N-terminal methylation motif K02457 - - 0.00001881 53.0
TH1_k127_495388_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1774.0
TH1_k127_495388_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1177.0
TH1_k127_495388_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000004933 224.0
TH1_k127_495388_11 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000000000000000006424 184.0
TH1_k127_495388_12 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000007157 184.0
TH1_k127_495388_13 - - - - 0.000000000000000000000000000000000000000000002954 168.0
TH1_k127_495388_14 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000001338 154.0
TH1_k127_495388_15 histidine kinase A domain protein - - - 0.0000000000000000000000000000005517 130.0
TH1_k127_495388_16 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000009292 126.0
TH1_k127_495388_17 Belongs to the ompA family K03286 - - 0.000000000000000000000000000753 114.0
TH1_k127_495388_18 Cytochrome c7 and related cytochrome c - - - 0.000000000000001748 81.0
TH1_k127_495388_19 Bacterial PH domain - - - 0.000000000001104 74.0
TH1_k127_495388_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 538.0
TH1_k127_495388_20 Membrane - - - 0.00000000004706 71.0
TH1_k127_495388_3 PFAM Outer membrane efflux protein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 541.0
TH1_k127_495388_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 488.0
TH1_k127_495388_5 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 492.0
TH1_k127_495388_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 415.0
TH1_k127_495388_7 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 359.0
TH1_k127_495388_8 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 309.0
TH1_k127_495388_9 PFAM flavin reductase domain protein FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000002709 234.0
TH1_k127_4998158_0 protein secretion K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 606.0
TH1_k127_4998158_1 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 586.0
TH1_k127_4998158_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 504.0
TH1_k127_4998158_3 Multicopper oxidase K08100 - 1.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 418.0
TH1_k127_4998158_4 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 327.0
TH1_k127_4998158_5 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000001065 169.0
TH1_k127_4998158_6 Transcription factor zinc-finger - - - 0.0000000000000000000000001275 113.0
TH1_k127_4998158_8 von Willebrand factor, type A - - - 0.00000001691 59.0
TH1_k127_5076245_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.797e-274 854.0
TH1_k127_5076245_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.627e-247 769.0
TH1_k127_5076245_10 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 359.0
TH1_k127_5076245_11 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 352.0
TH1_k127_5076245_12 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 365.0
TH1_k127_5076245_13 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 342.0
TH1_k127_5076245_14 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 343.0
TH1_k127_5076245_15 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 289.0
TH1_k127_5076245_16 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 285.0
TH1_k127_5076245_17 cellulose synthase operon protein YhjU - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001129 296.0
TH1_k127_5076245_18 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004811 256.0
TH1_k127_5076245_19 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000001529 256.0
TH1_k127_5076245_2 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 6.872e-213 671.0
TH1_k127_5076245_20 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000002244 231.0
TH1_k127_5076245_21 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000002809 207.0
TH1_k127_5076245_22 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000001432 195.0
TH1_k127_5076245_23 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000716 183.0
TH1_k127_5076245_24 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000633 183.0
TH1_k127_5076245_25 YbbR-like protein - - - 0.000000000000000000000000000000000000000000000483 174.0
TH1_k127_5076245_26 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000000000000000000001979 161.0
TH1_k127_5076245_27 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000009126 165.0
TH1_k127_5076245_28 Transcriptional regulator - - - 0.000000000000000000000000000000000000001634 155.0
TH1_k127_5076245_29 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000001104 130.0
TH1_k127_5076245_3 Endoribonuclease that initiates mRNA decay K18682 - - 9.25e-207 655.0
TH1_k127_5076245_31 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000001469 96.0
TH1_k127_5076245_32 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000002046 87.0
TH1_k127_5076245_33 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000009505 83.0
TH1_k127_5076245_34 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000001311 74.0
TH1_k127_5076245_35 - - - - 0.00000001095 61.0
TH1_k127_5076245_36 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000005274 58.0
TH1_k127_5076245_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 536.0
TH1_k127_5076245_5 TonB-dependent Receptor Plug Domain K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 519.0
TH1_k127_5076245_6 Glycosyl transferase family 21 K00694 - 2.4.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 445.0
TH1_k127_5076245_7 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 422.0
TH1_k127_5076245_8 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 398.0
TH1_k127_5076245_9 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 379.0
TH1_k127_5199947_0 PFAM type III restriction protein res subunit - - - 2.012e-311 972.0
TH1_k127_5199947_1 Calcineurin-like phosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 317.0
TH1_k127_5199947_10 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000001101 64.0
TH1_k127_5199947_2 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000000000003585 206.0
TH1_k127_5199947_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000001099 199.0
TH1_k127_5199947_4 PFAM pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000000007078 169.0
TH1_k127_5199947_5 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.0000000000000000000000000000000000000000009504 161.0
TH1_k127_5199947_6 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000004547 125.0
TH1_k127_5199947_7 PIN domain - - - 0.00000000000000000000001926 104.0
TH1_k127_5325740_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 347.0
TH1_k127_5325740_1 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 361.0
TH1_k127_5325740_10 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000005333 111.0
TH1_k127_5325740_11 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000006724 103.0
TH1_k127_5325740_12 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000003805 79.0
TH1_k127_5325740_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 329.0
TH1_k127_5325740_3 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 338.0
TH1_k127_5325740_4 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 331.0
TH1_k127_5325740_5 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 288.0
TH1_k127_5325740_6 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 281.0
TH1_k127_5325740_7 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001113 302.0
TH1_k127_5325740_8 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000001539 172.0
TH1_k127_5325740_9 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000001002 173.0
TH1_k127_532623_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 2.188e-314 971.0
TH1_k127_532623_1 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 3.377e-241 764.0
TH1_k127_532623_2 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00335,K18331 - 1.12.1.3,1.6.5.3 2.009e-212 684.0
TH1_k127_532623_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 473.0
TH1_k127_532623_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000002802 214.0
TH1_k127_532623_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.0000000000000000000000000000000000000000000000000000026 198.0
TH1_k127_532623_6 Universal stress protein - - - 0.0000000000000000000000000000000000000005319 152.0
TH1_k127_532623_7 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000000009999 151.0
TH1_k127_532623_8 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000274 68.0
TH1_k127_532623_9 response to heat K07090 - - 0.00000002815 55.0
TH1_k127_5367237_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 2.938e-238 744.0
TH1_k127_5367237_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 451.0
TH1_k127_5367237_10 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000001217 205.0
TH1_k127_5367237_11 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000142 123.0
TH1_k127_5367237_12 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000001009 98.0
TH1_k127_5367237_13 Protein of unknown function (DUF2905) - - - 0.000000000000000000255 90.0
TH1_k127_5367237_14 3D domain protein - - - 0.000000009148 62.0
TH1_k127_5367237_15 n-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0008446 50.0
TH1_k127_5367237_2 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 399.0
TH1_k127_5367237_3 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 374.0
TH1_k127_5367237_4 Major Facilitator Superfamily K16210 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 362.0
TH1_k127_5367237_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 340.0
TH1_k127_5367237_6 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004759 276.0
TH1_k127_5367237_7 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000003613 263.0
TH1_k127_5367237_8 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.0000000000000000000000000000000000000000000000000000000002402 208.0
TH1_k127_5367237_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000002546 195.0
TH1_k127_5429054_0 Heat shock 70 kDa protein K04043 - - 2.891e-320 989.0
TH1_k127_5429054_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.845e-280 875.0
TH1_k127_5429054_10 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 484.0
TH1_k127_5429054_11 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 488.0
TH1_k127_5429054_12 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 466.0
TH1_k127_5429054_13 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 459.0
TH1_k127_5429054_14 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 445.0
TH1_k127_5429054_15 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 367.0
TH1_k127_5429054_16 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 373.0
TH1_k127_5429054_17 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 351.0
TH1_k127_5429054_18 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 327.0
TH1_k127_5429054_19 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 310.0
TH1_k127_5429054_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 2.1e-205 641.0
TH1_k127_5429054_20 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 304.0
TH1_k127_5429054_21 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 287.0
TH1_k127_5429054_22 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001361 286.0
TH1_k127_5429054_23 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002305 284.0
TH1_k127_5429054_24 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000171 267.0
TH1_k127_5429054_25 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001021 276.0
TH1_k127_5429054_26 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003778 263.0
TH1_k127_5429054_27 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000157 266.0
TH1_k127_5429054_28 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000145 257.0
TH1_k127_5429054_29 endonuclease III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003856 258.0
TH1_k127_5429054_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 3.123e-201 631.0
TH1_k127_5429054_30 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000001079 245.0
TH1_k127_5429054_31 Protein of unknown function (DUF1460) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003587 242.0
TH1_k127_5429054_32 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000008768 241.0
TH1_k127_5429054_33 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000003681 220.0
TH1_k127_5429054_34 PFAM Phosphomethylpyrimidine kinase type-1 K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000008442 224.0
TH1_k127_5429054_35 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000005877 202.0
TH1_k127_5429054_36 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000002034 196.0
TH1_k127_5429054_37 SMART Signal transduction response regulator, receiver domain - - - 0.00000000000000000000000000000000000000000000000000006053 199.0
TH1_k127_5429054_38 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000697 208.0
TH1_k127_5429054_39 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000006269 186.0
TH1_k127_5429054_4 Fructose-bisphosphate aldolase class-II - - - 6.599e-197 622.0
TH1_k127_5429054_40 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000006505 172.0
TH1_k127_5429054_41 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000009769 171.0
TH1_k127_5429054_42 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000003467 176.0
TH1_k127_5429054_43 PFAM Pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000164 167.0
TH1_k127_5429054_44 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000000004468 152.0
TH1_k127_5429054_45 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000003432 153.0
TH1_k127_5429054_46 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000001554 157.0
TH1_k127_5429054_47 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000001856 151.0
TH1_k127_5429054_48 protein conserved in bacteria - - - 0.0000000000000000000000000000000000004155 145.0
TH1_k127_5429054_49 radical SAM domain protein - - - 0.0000000000000000000000000000000000105 151.0
TH1_k127_5429054_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 586.0
TH1_k127_5429054_50 Phosphoesterase - - - 0.0000000000000000000000000000003823 126.0
TH1_k127_5429054_51 PFAM Smr protein MutS2 - - - 0.000000000000000000000000000003011 127.0
TH1_k127_5429054_52 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000000007136 123.0
TH1_k127_5429054_53 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000003456 118.0
TH1_k127_5429054_54 Protein of unknown function (DUF2628) - - - 0.00000000000000000000000005523 111.0
TH1_k127_5429054_55 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000009949 110.0
TH1_k127_5429054_56 Protein of unknown function (DUF507) - - - 0.0000000000000000000000001737 108.0
TH1_k127_5429054_57 Protein of unknown function (DUF507) - - - 0.0000000000000000000000001792 109.0
TH1_k127_5429054_58 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000001559 104.0
TH1_k127_5429054_59 PFAM Pterin binding enzyme K00548 - 2.1.1.13 0.00000000000000002059 92.0
TH1_k127_5429054_6 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 573.0
TH1_k127_5429054_60 energy transducer activity K03646,K03832 - - 0.0000000000000007582 86.0
TH1_k127_5429054_62 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000002243 70.0
TH1_k127_5429054_63 Methyltransferase type 11 - - - 0.000000000006261 73.0
TH1_k127_5429054_64 integral membrane protein - - - 0.00000000004744 70.0
TH1_k127_5429054_65 Glutaredoxin K03676 - - 0.0000000002588 62.0
TH1_k127_5429054_67 NAD(P)H dehydrogenase K00355 - 1.6.5.2 0.00001425 47.0
TH1_k127_5429054_7 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 578.0
TH1_k127_5429054_8 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 560.0
TH1_k127_5429054_9 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 545.0
TH1_k127_561448_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.854e-286 902.0
TH1_k127_561448_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 563.0
TH1_k127_561448_10 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000007525 164.0
TH1_k127_561448_11 - - - - 0.00000000000000000000000000000000001249 140.0
TH1_k127_561448_2 Von Willebrand factor type A K02448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 442.0
TH1_k127_561448_3 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 396.0
TH1_k127_561448_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 369.0
TH1_k127_561448_5 CbbQ/NirQ/NorQ C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 337.0
TH1_k127_561448_6 Ferritin Dps family protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 294.0
TH1_k127_561448_7 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007739 242.0
TH1_k127_561448_8 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000001344 213.0
TH1_k127_561448_9 Transposase for insertion sequence element - - - 0.0000000000000000000000000000000000000000115 167.0
TH1_k127_5930960_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 402.0
TH1_k127_5930960_1 COG3385 FOG Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005772 271.0
TH1_k127_5930960_2 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K19312 GO:0003674,GO:0003824,GO:0004658,GO:0016421,GO:0016874,GO:0016885 2.1.3.15,6.4.1.2,6.4.1.3 0.00000007341 54.0
TH1_k127_6234885_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1138.0
TH1_k127_6234885_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 1.411e-252 801.0
TH1_k127_6234885_10 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 433.0
TH1_k127_6234885_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 431.0
TH1_k127_6234885_12 PFAM PfkB K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 402.0
TH1_k127_6234885_13 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 392.0
TH1_k127_6234885_14 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 394.0
TH1_k127_6234885_15 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 371.0
TH1_k127_6234885_16 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009367 373.0
TH1_k127_6234885_17 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 326.0
TH1_k127_6234885_18 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 323.0
TH1_k127_6234885_19 Putative Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 291.0
TH1_k127_6234885_2 GTP-binding GTPase Middle Region K03665 - - 1.082e-200 638.0
TH1_k127_6234885_20 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003725 279.0
TH1_k127_6234885_21 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000178 269.0
TH1_k127_6234885_22 cyclic diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001131 255.0
TH1_k127_6234885_23 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000001957 240.0
TH1_k127_6234885_24 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000008183 250.0
TH1_k127_6234885_25 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000005371 227.0
TH1_k127_6234885_26 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000002207 222.0
TH1_k127_6234885_27 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000002631 220.0
TH1_k127_6234885_28 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000005014 221.0
TH1_k127_6234885_29 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000194 211.0
TH1_k127_6234885_3 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 591.0
TH1_k127_6234885_30 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000002479 187.0
TH1_k127_6234885_32 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001054 163.0
TH1_k127_6234885_33 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001292 149.0
TH1_k127_6234885_34 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000004362 147.0
TH1_k127_6234885_35 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000002867 131.0
TH1_k127_6234885_36 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000005831 122.0
TH1_k127_6234885_37 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000007075 114.0
TH1_k127_6234885_38 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000002289 117.0
TH1_k127_6234885_39 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000003974 106.0
TH1_k127_6234885_4 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 571.0
TH1_k127_6234885_40 AMP binding - - - 0.0000000000002584 73.0
TH1_k127_6234885_41 electron transfer activity K03616 - - 0.00006949 48.0
TH1_k127_6234885_42 Tetratricopeptide repeat - - - 0.0005146 47.0
TH1_k127_6234885_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 567.0
TH1_k127_6234885_6 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 530.0
TH1_k127_6234885_7 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 499.0
TH1_k127_6234885_8 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 484.0
TH1_k127_6234885_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 478.0
TH1_k127_6242938_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 6.406e-244 760.0
TH1_k127_6242938_1 cytochrome c nitrate reductase, small subunit K15876 - - 0.00000000000000000000000000000000000000000000000001213 184.0
TH1_k127_6242938_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000164 113.0
TH1_k127_6242938_3 Nitroreductase family - - - 0.000000009225 57.0
TH1_k127_6359475_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 451.0
TH1_k127_6359475_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 450.0
TH1_k127_6359475_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000007394 211.0
TH1_k127_6359475_11 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000001873 192.0
TH1_k127_6359475_12 S1 domain K00243 - - 0.0000000000000000000000000000000000000000000000000003909 189.0
TH1_k127_6359475_13 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000002004 182.0
TH1_k127_6359475_14 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000001577 141.0
TH1_k127_6359475_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 389.0
TH1_k127_6359475_3 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 327.0
TH1_k127_6359475_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000225 305.0
TH1_k127_6359475_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002541 263.0
TH1_k127_6359475_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000007853 254.0
TH1_k127_6359475_7 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001607 242.0
TH1_k127_6359475_8 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000466 231.0
TH1_k127_6359475_9 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000007616 215.0
TH1_k127_6381416_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1030.0
TH1_k127_6381416_1 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 6.127e-231 719.0
TH1_k127_6381416_10 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000007252 200.0
TH1_k127_6381416_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000002537 126.0
TH1_k127_6381416_12 - - - - 0.0000000000000001314 82.0
TH1_k127_6381416_13 pfam yhs - - - 0.000000000000009593 75.0
TH1_k127_6381416_14 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain - - - 0.00000001979 65.0
TH1_k127_6381416_15 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000002863 58.0
TH1_k127_6381416_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 608.0
TH1_k127_6381416_3 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 551.0
TH1_k127_6381416_4 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 502.0
TH1_k127_6381416_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 393.0
TH1_k127_6381416_6 COG1194 A G-specific DNA glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 344.0
TH1_k127_6381416_7 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 322.0
TH1_k127_6381416_8 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000002787 222.0
TH1_k127_6381416_9 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000003258 205.0
TH1_k127_6410436_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 4.873e-317 994.0
TH1_k127_6410436_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.775e-200 637.0
TH1_k127_6410436_10 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 287.0
TH1_k127_6410436_11 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001068 281.0
TH1_k127_6410436_12 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000000000000000000263 202.0
TH1_k127_6410436_13 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000002438 195.0
TH1_k127_6410436_14 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.0000000000000000000000000000000000000000001829 164.0
TH1_k127_6410436_15 - - - - 0.00000000000000000000000000000000000002402 159.0
TH1_k127_6410436_16 - - - - 0.00000000000000000000000000003354 122.0
TH1_k127_6410436_2 Ftsk_gamma K03466 - - 2.105e-197 637.0
TH1_k127_6410436_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 611.0
TH1_k127_6410436_4 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 572.0
TH1_k127_6410436_5 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 550.0
TH1_k127_6410436_6 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 490.0
TH1_k127_6410436_7 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 370.0
TH1_k127_6410436_8 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 369.0
TH1_k127_6410436_9 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 306.0
TH1_k127_6521180_0 PFAM Radical SAM - - - 2.375e-220 696.0
TH1_k127_6521180_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 358.0
TH1_k127_6521180_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 314.0
TH1_k127_6521180_3 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000001305 158.0
TH1_k127_6521180_4 Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000003895 141.0
TH1_k127_6521180_5 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000002722 95.0
TH1_k127_6521180_6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000005846 79.0
TH1_k127_6544796_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 402.0
TH1_k127_6544796_1 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 349.0
TH1_k127_6544796_2 Thiamine biosynthesis protein (ThiI) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000155 293.0
TH1_k127_6544796_3 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000005908 239.0
TH1_k127_6618749_0 FAD binding domain K00278 - 1.4.3.16 1.45e-204 652.0
TH1_k127_6618749_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 439.0
TH1_k127_6618749_10 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000009743 179.0
TH1_k127_6618749_11 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000003086 175.0
TH1_k127_6618749_12 nuclease activity K06218,K07334 - - 0.0000000000000000000006331 99.0
TH1_k127_6618749_13 sequence-specific DNA binding K18830 - - 0.0008264 43.0
TH1_k127_6618749_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 415.0
TH1_k127_6618749_3 binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 412.0
TH1_k127_6618749_4 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004039 265.0
TH1_k127_6618749_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000007447 244.0
TH1_k127_6618749_6 Glycosyltransferase like family 2 K12992 - - 0.000000000000000000000000000000000000000000000000000000000000000003194 232.0
TH1_k127_6618749_7 PFAM Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000009502 232.0
TH1_k127_6618749_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000006214 210.0
TH1_k127_6618749_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000001527 207.0
TH1_k127_6698990_0 Retron-type reverse transcriptase K00986 - 2.7.7.49 8.057e-223 704.0
TH1_k127_6698990_1 GH3 auxin-responsive promoter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 375.0
TH1_k127_6698990_2 Mandelate racemase muconate lactonizing enzyme K01856,K19802 - 5.1.1.20,5.5.1.1 0.00000000000000000000000000000000000000628 156.0
TH1_k127_6698990_3 Fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000004665 88.0
TH1_k127_6698990_4 Crp Fnr family transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.000000005491 63.0
TH1_k127_704478_0 Histidine kinase - - - 1.37e-210 690.0
TH1_k127_704478_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 462.0
TH1_k127_704478_10 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 302.0
TH1_k127_704478_11 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 303.0
TH1_k127_704478_12 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002627 276.0
TH1_k127_704478_13 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000001437 247.0
TH1_k127_704478_14 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000001184 226.0
TH1_k127_704478_15 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000747 216.0
TH1_k127_704478_16 - - - - 0.00000000000000000000000000000000000000000000000001607 182.0
TH1_k127_704478_17 the in vivo substrate is - - - 0.000000000000000000000000000000000000000000000000123 188.0
TH1_k127_704478_18 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000001094 171.0
TH1_k127_704478_19 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000005778 169.0
TH1_k127_704478_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 425.0
TH1_k127_704478_20 Universal stress protein K06149 - - 0.0000000000000000000000000000000000402 139.0
TH1_k127_704478_21 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000001485 138.0
TH1_k127_704478_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.000000000000000000000000000000003497 140.0
TH1_k127_704478_23 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000428 133.0
TH1_k127_704478_24 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000007296 130.0
TH1_k127_704478_25 proteolysis K03665 - - 0.000000000000000000000000000001107 127.0
TH1_k127_704478_26 - - - - 0.0000000000000000000000001746 107.0
TH1_k127_704478_27 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000371 83.0
TH1_k127_704478_28 Protein of unknown function DUF72 - - - 0.00000003729 57.0
TH1_k127_704478_3 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 429.0
TH1_k127_704478_4 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 332.0
TH1_k127_704478_5 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 322.0
TH1_k127_704478_6 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 317.0
TH1_k127_704478_7 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 315.0
TH1_k127_704478_8 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 316.0
TH1_k127_704478_9 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 309.0
TH1_k127_7361642_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.444e-249 790.0
TH1_k127_7361642_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 7.828e-223 706.0
TH1_k127_7361642_10 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000002887 189.0
TH1_k127_7361642_11 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000001826 154.0
TH1_k127_7361642_12 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000000007043 149.0
TH1_k127_7361642_13 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000003684 115.0
TH1_k127_7361642_14 nucleotidyltransferase activity K07075 - - 0.0000000000000000000000005583 111.0
TH1_k127_7361642_16 Kinase/pyrophosphorylase K09773 - 2.7.11.33,2.7.4.28 0.0000001111 55.0
TH1_k127_7361642_2 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 528.0
TH1_k127_7361642_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 424.0
TH1_k127_7361642_4 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 373.0
TH1_k127_7361642_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 315.0
TH1_k127_7361642_6 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001031 273.0
TH1_k127_7361642_7 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000001199 224.0
TH1_k127_7361642_8 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000002125 222.0
TH1_k127_7361642_9 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000005653 192.0
TH1_k127_7402867_0 Asparagine synthase K01953 - 6.3.5.4 7.26e-237 749.0
TH1_k127_7402867_1 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 587.0
TH1_k127_7402867_2 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007021 334.0
TH1_k127_7402867_3 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002371 293.0
TH1_k127_7402867_4 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000001105 131.0
TH1_k127_7402867_5 Phosphopantetheine attachment site - - - 0.0000000000000000000003442 98.0
TH1_k127_7402867_6 TIGRFAM N-acetyl sugar amidotransferase - - - 0.000002774 52.0
TH1_k127_7521751_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.575e-278 872.0
TH1_k127_7521751_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 1.027e-217 687.0
TH1_k127_7521751_10 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 455.0
TH1_k127_7521751_11 coenzyme F420 hydrogenase activity K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 385.0
TH1_k127_7521751_12 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 342.0
TH1_k127_7521751_13 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 324.0
TH1_k127_7521751_14 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 330.0
TH1_k127_7521751_15 Belongs to the MurCDEF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 327.0
TH1_k127_7521751_16 PFAM import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 316.0
TH1_k127_7521751_17 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 310.0
TH1_k127_7521751_18 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 310.0
TH1_k127_7521751_19 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 301.0
TH1_k127_7521751_2 Nickel-dependent hydrogenase - - - 7.825e-213 668.0
TH1_k127_7521751_20 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 287.0
TH1_k127_7521751_21 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001798 282.0
TH1_k127_7521751_22 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000001517 239.0
TH1_k127_7521751_23 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000569 222.0
TH1_k127_7521751_24 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000007731 194.0
TH1_k127_7521751_25 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000000000000001048 156.0
TH1_k127_7521751_26 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.00000000000000000000000000000000000001574 147.0
TH1_k127_7521751_27 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000000001054 99.0
TH1_k127_7521751_28 Putative zinc- or iron-chelating domain - - - 0.000000000000005406 80.0
TH1_k127_7521751_29 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000008945 75.0
TH1_k127_7521751_3 Metallo-beta-lactamase superfamily - - - 5.535e-195 622.0
TH1_k127_7521751_30 peptidyl-tyrosine sulfation - - - 0.00000000003592 73.0
TH1_k127_7521751_31 - - - - 0.000001531 56.0
TH1_k127_7521751_4 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 592.0
TH1_k127_7521751_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 592.0
TH1_k127_7521751_6 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 572.0
TH1_k127_7521751_7 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 559.0
TH1_k127_7521751_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 462.0
TH1_k127_7521751_9 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 471.0
TH1_k127_7646335_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1086.0
TH1_k127_7646335_1 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 518.0
TH1_k127_7646335_10 Transposase - - - 0.0000000000000000000000000000000008123 132.0
TH1_k127_7646335_11 Thioredoxin-like - - - 0.00000000000000000000000000000000358 134.0
TH1_k127_7646335_12 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000001453 106.0
TH1_k127_7646335_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 433.0
TH1_k127_7646335_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 421.0
TH1_k127_7646335_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 397.0
TH1_k127_7646335_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 341.0
TH1_k127_7646335_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000002175 168.0
TH1_k127_7646335_7 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000711 156.0
TH1_k127_7646335_8 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000001539 151.0
TH1_k127_7646335_9 ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000002293 140.0
TH1_k127_7659492_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.915e-296 925.0
TH1_k127_7659492_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 9.757e-247 786.0
TH1_k127_7659492_10 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005504 265.0
TH1_k127_7659492_11 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000001521 210.0
TH1_k127_7659492_12 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000002899 176.0
TH1_k127_7659492_13 Enzyme of the cupin superfamily K06995 - - 0.0000000000000000000000000000000004743 132.0
TH1_k127_7659492_14 S23 ribosomal protein - - - 0.000000000000000000000000000002026 125.0
TH1_k127_7659492_15 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000454 121.0
TH1_k127_7659492_16 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.000000000000000000000001884 109.0
TH1_k127_7659492_17 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.000000000000000005589 90.0
TH1_k127_7659492_18 - - - - 0.00000000001131 66.0
TH1_k127_7659492_19 Prokaryotic N-terminal methylation motif K02671 - - 0.0009972 48.0
TH1_k127_7659492_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.158e-201 635.0
TH1_k127_7659492_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 460.0
TH1_k127_7659492_4 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 465.0
TH1_k127_7659492_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 382.0
TH1_k127_7659492_6 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 370.0
TH1_k127_7659492_7 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 350.0
TH1_k127_7659492_8 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 339.0
TH1_k127_7659492_9 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 299.0
TH1_k127_780115_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 331.0
TH1_k127_780115_1 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000001203 225.0
TH1_k127_780115_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000000000001488 134.0
TH1_k127_780115_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000006475 107.0
TH1_k127_780115_4 Tetratricopeptide repeat - - - 0.00002396 53.0
TH1_k127_7904586_0 B3/4 domain K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 614.0
TH1_k127_7904586_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 506.0
TH1_k127_7904586_10 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 315.0
TH1_k127_7904586_11 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 314.0
TH1_k127_7904586_12 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 306.0
TH1_k127_7904586_13 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001024 284.0
TH1_k127_7904586_14 Protein of unknown function DUF89 K09116,K09680 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003515 280.0
TH1_k127_7904586_15 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000108 254.0
TH1_k127_7904586_16 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000001292 207.0
TH1_k127_7904586_17 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000000000000000000000354 204.0
TH1_k127_7904586_18 belongs to the Fur family K02076,K03711,K09823 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000001102 182.0
TH1_k127_7904586_19 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000006387 159.0
TH1_k127_7904586_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 464.0
TH1_k127_7904586_20 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000008793 157.0
TH1_k127_7904586_21 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000002502 163.0
TH1_k127_7904586_22 CHASE2 - - - 0.0000000000000000000000000000000000001664 148.0
TH1_k127_7904586_23 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000000000007746 132.0
TH1_k127_7904586_24 Ribosomal protein S16 K02959 - - 0.000000000000000000000000002168 112.0
TH1_k127_7904586_25 serine-type aminopeptidase activity K02030,K14475 - - 0.0000000002893 66.0
TH1_k127_7904586_3 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 436.0
TH1_k127_7904586_4 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 406.0
TH1_k127_7904586_5 PFAM Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 381.0
TH1_k127_7904586_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 372.0
TH1_k127_7904586_7 wide pore channel activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 361.0
TH1_k127_7904586_8 AAA domain, putative AbiEii toxin, Type IV TA system K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 332.0
TH1_k127_7904586_9 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 316.0
TH1_k127_7905326_0 ABC transporter K06020 - 3.6.3.25 9.027e-195 611.0
TH1_k127_7905326_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 640.0
TH1_k127_7905326_10 Macrocin-O-methyltransferase (TylF) K05303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000612 285.0
TH1_k127_7905326_11 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003687 280.0
TH1_k127_7905326_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002885 244.0
TH1_k127_7905326_13 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000005362 198.0
TH1_k127_7905326_14 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000009332 186.0
TH1_k127_7905326_15 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000002864 181.0
TH1_k127_7905326_16 Glycosyltransferase like family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000003068 186.0
TH1_k127_7905326_17 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000006558 173.0
TH1_k127_7905326_18 Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000009527 180.0
TH1_k127_7905326_19 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000003896 178.0
TH1_k127_7905326_2 ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 451.0
TH1_k127_7905326_20 PFAM Glycosyl transferase family 2 K12992 - - 0.000000000000000000000000000000000001646 153.0
TH1_k127_7905326_21 Methyltransferase domain - - - 0.0000000000000000000000000000001118 133.0
TH1_k127_7905326_22 methyltransferase activity K02169 - 2.1.1.197 0.000000000000000000000000008582 122.0
TH1_k127_7905326_23 GTP-binding protein TypA K06207 - - 0.0001071 44.0
TH1_k127_7905326_24 NAD(P)H-binding K01709,K01710 - 4.2.1.45,4.2.1.46 0.0003512 47.0
TH1_k127_7905326_3 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 419.0
TH1_k127_7905326_4 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 386.0
TH1_k127_7905326_5 Transport permease protein K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 359.0
TH1_k127_7905326_6 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 347.0
TH1_k127_7905326_7 PFAM Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 328.0
TH1_k127_7905326_8 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 333.0
TH1_k127_7905326_9 carbohydrate metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 306.0
TH1_k127_8099721_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1251.0
TH1_k127_8099721_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1045.0
TH1_k127_8099721_10 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 481.0
TH1_k127_8099721_11 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 432.0
TH1_k127_8099721_12 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 391.0
TH1_k127_8099721_13 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 385.0
TH1_k127_8099721_14 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 366.0
TH1_k127_8099721_15 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 361.0
TH1_k127_8099721_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 367.0
TH1_k127_8099721_17 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 345.0
TH1_k127_8099721_18 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 336.0
TH1_k127_8099721_19 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 319.0
TH1_k127_8099721_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.161e-287 901.0
TH1_k127_8099721_20 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 322.0
TH1_k127_8099721_21 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 315.0
TH1_k127_8099721_22 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 314.0
TH1_k127_8099721_23 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 285.0
TH1_k127_8099721_24 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001008 283.0
TH1_k127_8099721_25 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002169 284.0
TH1_k127_8099721_26 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001922 272.0
TH1_k127_8099721_27 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005016 267.0
TH1_k127_8099721_28 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000001073 254.0
TH1_k127_8099721_29 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008908 252.0
TH1_k127_8099721_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.905e-220 688.0
TH1_k127_8099721_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004528 239.0
TH1_k127_8099721_31 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000004033 231.0
TH1_k127_8099721_32 Redoxin K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000006159 231.0
TH1_k127_8099721_33 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000003869 226.0
TH1_k127_8099721_34 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000006657 228.0
TH1_k127_8099721_35 DegT/DnrJ/EryC1/StrS aminotransferase family K14260 - 2.6.1.2,2.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000918 234.0
TH1_k127_8099721_36 HDIG domain protein K06950 - - 0.00000000000000000000000000000000000000000000000000000000000001474 220.0
TH1_k127_8099721_37 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000003644 212.0
TH1_k127_8099721_38 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003788 215.0
TH1_k127_8099721_39 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000006795 211.0
TH1_k127_8099721_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 592.0
TH1_k127_8099721_40 Acyltransferase family K16568 - - 0.0000000000000000000000000000000000000000000000000000000000168 220.0
TH1_k127_8099721_41 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000008076 205.0
TH1_k127_8099721_42 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000006769 183.0
TH1_k127_8099721_43 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000008459 204.0
TH1_k127_8099721_44 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000001764 177.0
TH1_k127_8099721_45 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001598 169.0
TH1_k127_8099721_46 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000001214 168.0
TH1_k127_8099721_47 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000008111 166.0
TH1_k127_8099721_48 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000000001116 165.0
TH1_k127_8099721_49 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000197 156.0
TH1_k127_8099721_5 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 563.0
TH1_k127_8099721_50 HNH nucleases - - - 0.00000000000000000000000000000000000000002476 156.0
TH1_k127_8099721_51 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000001653 153.0
TH1_k127_8099721_52 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000000006874 153.0
TH1_k127_8099721_53 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000105 145.0
TH1_k127_8099721_54 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000002362 140.0
TH1_k127_8099721_55 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000009544 127.0
TH1_k127_8099721_56 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000007642 124.0
TH1_k127_8099721_57 PFAM Glutaredoxin K06191 - - 0.00000000000000000000000000002005 119.0
TH1_k127_8099721_58 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000004197 117.0
TH1_k127_8099721_59 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000000000006848 127.0
TH1_k127_8099721_6 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 562.0
TH1_k127_8099721_60 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000001383 110.0
TH1_k127_8099721_61 Na -dependent transporter K03453 - - 0.0000000000000000000000001572 117.0
TH1_k127_8099721_62 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001764 106.0
TH1_k127_8099721_63 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000001772 111.0
TH1_k127_8099721_64 NIL - - - 0.000000000000000000000000264 106.0
TH1_k127_8099721_65 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001256 104.0
TH1_k127_8099721_66 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000001522 86.0
TH1_k127_8099721_67 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001423 75.0
TH1_k127_8099721_68 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000002992 72.0
TH1_k127_8099721_69 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000000008623 76.0
TH1_k127_8099721_7 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 558.0
TH1_k127_8099721_70 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000009377 68.0
TH1_k127_8099721_71 Putative regulatory protein - - - 0.000000784 53.0
TH1_k127_8099721_8 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 516.0
TH1_k127_8099721_9 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 501.0
TH1_k127_8322419_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 437.0
TH1_k127_8322419_1 Polysaccharide export protein K01991 - - 0.0000000000000000000000000000000000000000000001052 179.0
TH1_k127_8368872_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1064.0
TH1_k127_8368872_1 Multicopper oxidase - - - 2.994e-249 794.0
TH1_k127_8368872_2 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 436.0
TH1_k127_8368872_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 323.0
TH1_k127_8368872_4 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005343 281.0
TH1_k127_8368872_5 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000002233 267.0
TH1_k127_8368872_6 Copper resistance protein B precursor (CopB) K07233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001227 267.0
TH1_k127_8368872_7 Protein of unknown function (DUF2950) - - - 0.000000000000000000000004702 106.0
TH1_k127_8368872_8 Domain of unknown function (DUF4412) - - - 0.00000000000000000000005368 106.0
TH1_k127_8433738_0 Phosphoesterase, PA-phosphatase related K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000005617 118.0
TH1_k127_8433738_1 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000005642 75.0
TH1_k127_8433738_2 cheY-homologous receiver domain - - - 0.00000000004807 68.0
TH1_k127_8489645_0 Polysaccharide biosynthesis/export protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 527.0
TH1_k127_8489645_1 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 474.0
TH1_k127_8489645_10 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000004005 149.0
TH1_k127_8489645_12 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.00000000000000395 83.0
TH1_k127_8489645_2 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 378.0
TH1_k127_8489645_3 COG3524 Capsule polysaccharide export protein K10107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 299.0
TH1_k127_8489645_4 ABC-type polysaccharide polyol phosphate transport system ATPase component K09689 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 287.0
TH1_k127_8489645_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005275 280.0
TH1_k127_8489645_6 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001029 283.0
TH1_k127_8489645_7 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000006593 239.0
TH1_k127_8489645_8 Transport Permease Protein K09688 - - 0.0000000000000000000000000000000000000000000000000000000000000001815 229.0
TH1_k127_8489645_9 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000002261 178.0
TH1_k127_8533389_0 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 1.148e-215 679.0
TH1_k127_8533389_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.214e-207 653.0
TH1_k127_8533389_10 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000002691 218.0
TH1_k127_8533389_11 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000003171 207.0
TH1_k127_8533389_12 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000003021 180.0
TH1_k127_8533389_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000002547 178.0
TH1_k127_8533389_14 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000000000000000000000004494 169.0
TH1_k127_8533389_15 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000005666 169.0
TH1_k127_8533389_16 Domain of unknown function (DUF370) K09777 - - 0.00000000000000000000000000006643 118.0
TH1_k127_8533389_17 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000006536 115.0
TH1_k127_8533389_18 peptidyl-tyrosine sulfation - - - 0.0000000000000000001586 98.0
TH1_k127_8533389_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 1.334e-201 633.0
TH1_k127_8533389_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 500.0
TH1_k127_8533389_4 Mediates zinc uptake. May also transport other divalent cations K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 470.0
TH1_k127_8533389_5 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 437.0
TH1_k127_8533389_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 377.0
TH1_k127_8533389_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 299.0
TH1_k127_8533389_8 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 299.0
TH1_k127_8533389_9 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000007945 253.0
TH1_k127_8534772_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.593e-284 884.0
TH1_k127_8534772_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 1.201e-250 794.0
TH1_k127_8534772_10 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 313.0
TH1_k127_8534772_11 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000507 280.0
TH1_k127_8534772_12 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000001628 263.0
TH1_k127_8534772_13 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000002194 216.0
TH1_k127_8534772_14 - - - - 0.00000000000000000000000000000000000000000000000000005143 197.0
TH1_k127_8534772_15 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000006256 178.0
TH1_k127_8534772_16 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.0000000000000000000000000000000000000000104 158.0
TH1_k127_8534772_17 coenzyme F420 binding K00275 - 1.4.3.5 0.0000000000000000000000000000000000000005919 153.0
TH1_k127_8534772_18 Putative Ig domain - - - 0.0000000000000000000000000000000007127 151.0
TH1_k127_8534772_19 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000000008459 112.0
TH1_k127_8534772_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 563.0
TH1_k127_8534772_20 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000722 96.0
TH1_k127_8534772_21 Sporulation and spore germination - - - 0.0000000000000002226 86.0
TH1_k127_8534772_22 Protein conserved in bacteria K09928 - - 0.0000000000002254 75.0
TH1_k127_8534772_23 Ami_3 - - - 0.00000000001313 76.0
TH1_k127_8534772_3 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 450.0
TH1_k127_8534772_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 378.0
TH1_k127_8534772_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 358.0
TH1_k127_8534772_6 UV-endonuclease UvdE K13281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 348.0
TH1_k127_8534772_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 331.0
TH1_k127_8534772_8 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 318.0
TH1_k127_8534772_9 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 325.0
TH1_k127_871503_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1081.0
TH1_k127_871503_1 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 540.0
TH1_k127_871503_10 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000006755 178.0
TH1_k127_871503_11 shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000009004 164.0
TH1_k127_871503_12 Universal stress protein family - - - 0.00000000000000000000000237 108.0
TH1_k127_871503_13 RDD family - - - 0.00000000000000000000003164 104.0
TH1_k127_871503_2 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 518.0
TH1_k127_871503_3 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 464.0
TH1_k127_871503_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 416.0
TH1_k127_871503_5 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 358.0
TH1_k127_871503_6 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 343.0
TH1_k127_871503_7 helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 340.0
TH1_k127_871503_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 299.0
TH1_k127_871503_9 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000002129 213.0
TH1_k127_9269627_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 601.0
TH1_k127_9269627_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 562.0
TH1_k127_9269627_10 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000003354 223.0
TH1_k127_9269627_11 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000002377 218.0
TH1_k127_9269627_12 Fumarase C-terminus K01676,K03780 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000003076 188.0
TH1_k127_9269627_13 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000005354 189.0
TH1_k127_9269627_14 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000003079 185.0
TH1_k127_9269627_15 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000000001563 163.0
TH1_k127_9269627_16 RNA-binding protein containing a PIN domain K06962 - - 0.000000000000000000000000000000000000001187 153.0
TH1_k127_9269627_17 Uncharacterised ArCR, COG2043 - - - 0.000000000000001719 85.0
TH1_k127_9269627_18 COG1522 Transcriptional regulators - - - 0.00000000000005711 74.0
TH1_k127_9269627_19 Sporulation related domain - - - 0.000006251 56.0
TH1_k127_9269627_2 CAAX prenyl protease N-terminal, five membrane helices - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 492.0
TH1_k127_9269627_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 466.0
TH1_k127_9269627_4 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 431.0
TH1_k127_9269627_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 306.0
TH1_k127_9269627_6 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 307.0
TH1_k127_9269627_7 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001718 263.0
TH1_k127_9269627_8 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000008924 258.0
TH1_k127_9269627_9 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000004035 243.0
TH1_k127_9398491_0 Conserved region in glutamate synthase - - - 7.398e-273 846.0
TH1_k127_9398491_1 PFAM ferredoxin-dependent glutamate synthase - - - 4.219e-200 627.0
TH1_k127_9398491_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 501.0
TH1_k127_9398491_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 402.0
TH1_k127_9398491_4 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 394.0
TH1_k127_9398491_5 PFAM Radical SAM domain protein K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 372.0
TH1_k127_9398491_6 Belongs to the HesB IscA family K15724 - - 0.000000000000000000000005684 105.0
TH1_k127_9398491_7 Belongs to the Fur family K03711 - - 0.000000000000001198 78.0
TH1_k127_9442513_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.724e-279 871.0
TH1_k127_9442513_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 573.0
TH1_k127_9442513_2 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 422.0
TH1_k127_9442513_3 PFAM Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 403.0
TH1_k127_9442513_4 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001722 247.0
TH1_k127_9442513_5 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000001255 228.0
TH1_k127_9442513_6 Radical SAM K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000002161 237.0
TH1_k127_9442513_7 beta-galactosidase activity K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000428 219.0
TH1_k127_9442513_9 4Fe-4S single cluster domain - - - 0.00000000001515 74.0
TH1_k127_9514577_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1096.0
TH1_k127_9514577_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 9.999e-205 643.0
TH1_k127_9514577_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 376.0
TH1_k127_9514577_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 330.0
TH1_k127_9514577_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000001277 211.0
TH1_k127_9514577_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000958 139.0
TH1_k127_9514577_7 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000001864 82.0
TH1_k127_9514577_8 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000002246 85.0
TH1_k127_9628956_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 9.176e-314 979.0
TH1_k127_9628956_1 PFAM magnesium chelatase ChlI subunit K07391 - - 1.21e-205 651.0
TH1_k127_9628956_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 608.0
TH1_k127_9628956_3 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 468.0
TH1_k127_9628956_4 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 462.0
TH1_k127_9628956_5 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 297.0
TH1_k127_9628956_6 DUF167 - - - 0.00000000000001401 76.0
TH1_k127_9628956_7 Helix-turn-helix domain - - - 0.0002984 50.0
TH1_k127_9685929_0 ABC transporter K06158 - - 1.209e-215 684.0
TH1_k127_9685929_1 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 593.0
TH1_k127_9685929_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 367.0
TH1_k127_9685929_3 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000000003679 144.0
TH1_k127_9685929_4 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000002803 123.0
TH1_k127_9685929_5 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 0.00000000000000000000001353 100.0
TH1_k127_9685929_6 Protein of unknown function (DUF2628) - - - 0.00000000000000000000002149 105.0
TH1_k127_9685929_7 4-amino-4-deoxy-L-arabinose transferase and related - - - 0.0000000000004176 83.0
TH1_k127_9685929_8 Belongs to the SOS response-associated peptidase family - - - 0.0000000003144 63.0