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Overview

ID MAG03889
Name TH1_bin.79
Sample SMP0100
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA6898
Genus UBA6898
Species
Assembly information
Completeness (%) 78.21
Contamination (%) 2.36
GC content (%) 49.0
N50 (bp) 9,887
Genome size (bp) 1,683,045

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1701

Gene name Description KEGG GOs EC E-value Score Sequence
TH1_k127_1110009_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
TH1_k127_1110009_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 347.0
TH1_k127_1110009_2 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000001873 130.0
TH1_k127_1251180_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1549.0
TH1_k127_1251180_1 ABC transporter K06020 - 3.6.3.25 2.279e-309 956.0
TH1_k127_1251180_10 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000008532 168.0
TH1_k127_1251180_11 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000002762 172.0
TH1_k127_1251180_12 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000312 165.0
TH1_k127_1251180_13 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000009001 123.0
TH1_k127_1251180_15 calcium, potassium:sodium antiporter activity K07301 - - 0.000000000000000000000002194 108.0
TH1_k127_1251180_16 PFAM Phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.00000000000000000000006724 103.0
TH1_k127_1251180_17 - - - - 0.00000000000000000007464 92.0
TH1_k127_1251180_18 PFAM Sodium calcium exchanger membrane region K07301 - - 0.00000000001677 66.0
TH1_k127_1251180_19 Universal stress protein - - - 0.00000000008871 64.0
TH1_k127_1251180_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 6.696e-201 632.0
TH1_k127_1251180_3 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 524.0
TH1_k127_1251180_4 GHKL domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 514.0
TH1_k127_1251180_5 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 409.0
TH1_k127_1251180_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000131 287.0
TH1_k127_1251180_7 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006119 265.0
TH1_k127_1251180_8 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000002344 207.0
TH1_k127_1251180_9 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000000001674 173.0
TH1_k127_1270025_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.8e-216 682.0
TH1_k127_1270025_1 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 291.0
TH1_k127_1270025_2 - - - - 0.000000000000000000000000166 108.0
TH1_k127_1270025_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000001121 98.0
TH1_k127_1270025_4 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000001641 56.0
TH1_k127_127798_0 Dehydratase family K01687 - 4.2.1.9 1.76e-251 784.0
TH1_k127_127798_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 530.0
TH1_k127_127798_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 402.0
TH1_k127_127798_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000001219 241.0
TH1_k127_127798_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000003509 209.0
TH1_k127_127798_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000004691 104.0
TH1_k127_127798_6 Protein of unknown function (DUF465) K09794 - - 0.0000000000000007312 79.0
TH1_k127_1284248_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000001221 261.0
TH1_k127_1284248_1 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000001248 168.0
TH1_k127_1296597_0 NADH ubiquinone oxidoreductase K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 6.596e-200 639.0
TH1_k127_1296597_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009803 574.0
TH1_k127_1296597_10 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.0000000000000000000000000000000000000000000000001277 185.0
TH1_k127_1296597_11 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000002422 161.0
TH1_k127_1296597_12 heme-binding sites - - - 0.0000000000000000000000000000000000008297 148.0
TH1_k127_1296597_13 PHP-associated - - - 0.0000000000000000000000000000000004542 138.0
TH1_k127_1296597_14 denitrification pathway - - - 0.0000000000000000000000000000000006193 143.0
TH1_k127_1296597_15 cyclic nucleotide-binding - - - 0.000000000000000000000000000003703 124.0
TH1_k127_1296597_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000001527 117.0
TH1_k127_1296597_17 heat shock protein binding - - - 0.00000000000000000385 99.0
TH1_k127_1296597_18 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.00000001457 59.0
TH1_k127_1296597_2 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 462.0
TH1_k127_1296597_3 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 361.0
TH1_k127_1296597_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 290.0
TH1_k127_1296597_5 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 304.0
TH1_k127_1296597_6 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000136 269.0
TH1_k127_1296597_7 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002827 271.0
TH1_k127_1296597_8 PFAM peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005641 243.0
TH1_k127_1296597_9 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000003379 207.0
TH1_k127_1306239_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 497.0
TH1_k127_1306239_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 433.0
TH1_k127_1306239_2 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 391.0
TH1_k127_1306239_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.00000000000000000000000000000000000000008597 156.0
TH1_k127_1306239_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00003852 47.0
TH1_k127_1335179_0 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 569.0
TH1_k127_1335179_1 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 499.0
TH1_k127_1335179_10 Type II secretion system (T2SS), protein J K02459 - - 0.00000000000000006845 88.0
TH1_k127_1335179_11 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000002865 86.0
TH1_k127_1335179_12 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000004585 81.0
TH1_k127_1335179_13 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001222 72.0
TH1_k127_1335179_15 - - - - 0.000000005429 66.0
TH1_k127_1335179_16 Prokaryotic N-terminal methylation motif K02458 - - 0.0000002124 57.0
TH1_k127_1335179_17 Prokaryotic N-terminal methylation motif K02457 - - 0.000001025 56.0
TH1_k127_1335179_18 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0008517 51.0
TH1_k127_1335179_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 481.0
TH1_k127_1335179_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 415.0
TH1_k127_1335179_4 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000003684 194.0
TH1_k127_1335179_5 COG1459 Type II secretory pathway, component PulF K02455,K02653 - - 0.0000000000000000000000000000000000000000005147 172.0
TH1_k127_1335179_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000005271 151.0
TH1_k127_1335179_7 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000001678 113.0
TH1_k127_1335179_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000003394 107.0
TH1_k127_1335179_9 protein transport across the cell outer membrane K02452,K02463 - - 0.000000000000000000000001383 113.0
TH1_k127_1367416_0 Protein of unknown function (DUF1460) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006297 244.0
TH1_k127_1367416_1 Major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000021 196.0
TH1_k127_1367416_2 4Fe-4S binding domain - - - 0.000000000000000000000005506 111.0
TH1_k127_1385643_0 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 408.0
TH1_k127_1385643_1 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000001863 192.0
TH1_k127_1385643_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000007944 167.0
TH1_k127_1385643_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000007832 84.0
TH1_k127_1455841_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 8.138e-278 865.0
TH1_k127_1455841_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000009254 260.0
TH1_k127_1455841_2 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000005896 266.0
TH1_k127_1455841_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000002763 248.0
TH1_k127_1455841_4 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000005021 219.0
TH1_k127_1455841_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000001108 109.0
TH1_k127_1455841_6 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.00000000000000000001591 96.0
TH1_k127_1458430_0 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000004847 231.0
TH1_k127_1458430_1 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000273 164.0
TH1_k127_1458430_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000003066 145.0
TH1_k127_1469921_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1088.0
TH1_k127_1469921_1 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 563.0
TH1_k127_1469921_10 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000002282 220.0
TH1_k127_1469921_11 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000007327 209.0
TH1_k127_1469921_12 Pfam:TPM K08988 - - 0.0000000000000000000000000000000000000000000000000005436 191.0
TH1_k127_1469921_13 PFAM GGDEF domain containing protein K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000004721 191.0
TH1_k127_1469921_14 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000003777 169.0
TH1_k127_1469921_15 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000001287 159.0
TH1_k127_1469921_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000004671 151.0
TH1_k127_1469921_17 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000003644 147.0
TH1_k127_1469921_18 Thioredoxin-like - - - 0.0000000000000000000000000000000001001 139.0
TH1_k127_1469921_19 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000001713 140.0
TH1_k127_1469921_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 460.0
TH1_k127_1469921_20 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000007698 107.0
TH1_k127_1469921_21 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000002356 85.0
TH1_k127_1469921_23 - - - - 0.00000001208 60.0
TH1_k127_1469921_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 409.0
TH1_k127_1469921_4 K transport systems K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 385.0
TH1_k127_1469921_5 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 377.0
TH1_k127_1469921_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 365.0
TH1_k127_1469921_7 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 321.0
TH1_k127_1469921_8 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 296.0
TH1_k127_1469921_9 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000577 273.0
TH1_k127_1470548_0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000009858 114.0
TH1_k127_1470548_1 PFAM Nitroreductase - - - 0.000000000001438 68.0
TH1_k127_1470548_2 filament-like protein - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0009295,GO:0009507,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0016363,GO:0031974,GO:0031976,GO:0031981,GO:0031984,GO:0034357,GO:0034399,GO:0042646,GO:0042651,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0070013,GO:0097159,GO:1901363 - 0.00000097 62.0
TH1_k127_1470548_3 iron-sulfur cluster assembly - - - 0.000842 46.0
TH1_k127_1501998_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2076.0
TH1_k127_1501998_1 AAA domain K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 534.0
TH1_k127_1501998_2 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000004513 166.0
TH1_k127_1501998_3 - - - - 0.00000000000000000000013 102.0
TH1_k127_1501998_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000107 56.0
TH1_k127_1501998_5 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000707 55.0
TH1_k127_1533561_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000002132 245.0
TH1_k127_1533561_1 KR domain - - - 0.000000000000000000000000000000000000000000000004318 183.0
TH1_k127_1533561_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0000000000003409 76.0
TH1_k127_1533561_3 integral membrane protein - - - 0.00000000000146 76.0
TH1_k127_1638920_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 406.0
TH1_k127_1638920_1 - - - - 0.0000000000000009758 81.0
TH1_k127_1638920_2 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000003222 49.0
TH1_k127_1638920_3 Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.0006268 50.0
TH1_k127_1640550_0 Protein conserved in bacteria - - - 5.253e-231 740.0
TH1_k127_1640550_1 Histidine kinase - - - 3.432e-196 652.0
TH1_k127_1640550_2 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 602.0
TH1_k127_1640550_3 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 297.0
TH1_k127_1640550_4 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000297 267.0
TH1_k127_1640550_5 PFAM Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000006179 243.0
TH1_k127_1640550_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000004075 131.0
TH1_k127_1640550_7 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0001199 44.0
TH1_k127_164252_0 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 328.0
TH1_k127_164252_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000002027 205.0
TH1_k127_1689990_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 339.0
TH1_k127_1689990_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 303.0
TH1_k127_1689990_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000008038 164.0
TH1_k127_1689990_3 Polymer-forming cytoskeletal - - - 0.000000000000000001937 89.0
TH1_k127_1691575_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 316.0
TH1_k127_1691575_1 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 295.0
TH1_k127_1691575_2 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000006291 246.0
TH1_k127_1691575_3 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000006972 192.0
TH1_k127_1691575_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000001732 123.0
TH1_k127_1691575_5 PFAM ABC transporter related K09817 - - 0.0000000000000000000000000008584 113.0
TH1_k127_170899_0 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 467.0
TH1_k127_170899_1 PFAM peptidase K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 409.0
TH1_k127_170899_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000006441 202.0
TH1_k127_170899_3 Belongs to the MurCDEF family - - - 0.00000000000000000000001405 104.0
TH1_k127_170899_4 PFAM response regulator receiver K07662 - - 0.000000004131 69.0
TH1_k127_1794213_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001398 274.0
TH1_k127_1794213_1 - - - - 0.00000000000001914 79.0
TH1_k127_1794213_2 SurA N-terminal domain K03770 - 5.2.1.8 0.0004736 48.0
TH1_k127_180886_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 359.0
TH1_k127_180886_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 315.0
TH1_k127_180886_2 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 293.0
TH1_k127_180886_3 PFAM Mammalian cell entry related K02067 - - 0.000000000000000000000001425 114.0
TH1_k127_180886_4 - - - - 0.000000000000008846 76.0
TH1_k127_188142_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 6.497e-227 713.0
TH1_k127_188142_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 7.045e-204 655.0
TH1_k127_188142_10 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01769 - 4.6.1.2 0.00000000008764 71.0
TH1_k127_188142_11 Thioredoxin K03672 - 1.8.1.8 0.00006845 52.0
TH1_k127_188142_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 548.0
TH1_k127_188142_3 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 355.0
TH1_k127_188142_4 zinc ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004481 258.0
TH1_k127_188142_5 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000001468 140.0
TH1_k127_188142_6 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000007505 128.0
TH1_k127_188142_7 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000008463 129.0
TH1_k127_188142_8 Tetratricopeptide repeat-like domain - - - 0.00000000000000001217 91.0
TH1_k127_188142_9 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000003384 93.0
TH1_k127_1982778_0 Elongation factor G, domain IV K02355 - - 3.929e-294 917.0
TH1_k127_1982778_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000001561 241.0
TH1_k127_1982778_10 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.0000000000179 68.0
TH1_k127_1982778_2 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000012 229.0
TH1_k127_1982778_3 - - - - 0.000000000000000000000000000000000000000000005891 166.0
TH1_k127_1982778_4 Cytochrome P460 - - - 0.00000000000000000000000000000000000000003306 158.0
TH1_k127_1982778_5 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000006678 164.0
TH1_k127_1982778_6 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000000000005948 119.0
TH1_k127_1982778_7 PFAM Transposase K07491 - - 0.0000000000000000000000001335 107.0
TH1_k127_1982778_8 Cold shock K03704 - - 0.0000000000000000000000003721 106.0
TH1_k127_1982778_9 - - - - 0.00000000000000001087 85.0
TH1_k127_1986019_0 Telomere recombination K04656 - - 2.506e-245 781.0
TH1_k127_1986019_1 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 467.0
TH1_k127_1986019_2 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 381.0
TH1_k127_1986019_3 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 316.0
TH1_k127_1986019_4 nickel cation binding K04651,K19640 - - 0.0000000000000000000000000000006795 128.0
TH1_k127_1986019_5 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000573 108.0
TH1_k127_1986019_6 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.0000001048 61.0
TH1_k127_2039997_0 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003376 280.0
TH1_k127_2039997_1 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000000000000000000000000000003138 211.0
TH1_k127_2039997_2 Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000006515 175.0
TH1_k127_2039997_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000006308 142.0
TH1_k127_2039997_4 response regulator, receiver K03413 - - 0.00000000000000000578 90.0
TH1_k127_2039997_5 Multidrug transporter - - - 0.00000000003763 69.0
TH1_k127_2039997_6 Cysteine-rich small domain K07162 - - 0.000000001024 60.0
TH1_k127_207693_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009522 434.0
TH1_k127_207693_1 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000003164 223.0
TH1_k127_208013_0 aminopeptidase N - - - 0.00000000000000000000000000000000000000000000000000005564 199.0
TH1_k127_208013_1 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000000003063 120.0
TH1_k127_208013_2 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000002393 100.0
TH1_k127_208013_3 DNA integration - - - 0.00000000003844 70.0
TH1_k127_208013_4 Protein of unknown function (DUF1566) - - - 0.000003079 51.0
TH1_k127_2123105_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 3.555e-195 614.0
TH1_k127_2123105_1 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 462.0
TH1_k127_2123105_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 394.0
TH1_k127_2123105_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000001908 237.0
TH1_k127_2123105_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000008714 149.0
TH1_k127_2123105_5 Protein of unknown function (DUF1456) - - - 0.0000000000000000000000000001546 116.0
TH1_k127_2123105_6 conserved protein (DUF2132) - - - 0.00000000000000000000004989 99.0
TH1_k127_2129001_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.366e-202 642.0
TH1_k127_2129001_1 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 337.0
TH1_k127_2129001_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000975 188.0
TH1_k127_2171254_0 GTP-binding protein TypA K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 488.0
TH1_k127_2171254_1 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 322.0
TH1_k127_2171254_2 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000008449 163.0
TH1_k127_2185896_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 6.77e-322 1004.0
TH1_k127_2185896_1 Molecular chaperone. Has ATPase activity K04079 - - 8.071e-287 892.0
TH1_k127_2185896_10 LemA family K03744 - - 0.000000000000000000000000000000000000000000000004291 178.0
TH1_k127_2185896_11 metalloendopeptidase activity K03799 - - 0.00000000000000000000000000000000000000002434 170.0
TH1_k127_2185896_12 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000007659 145.0
TH1_k127_2185896_13 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000000000000000000000000000004713 134.0
TH1_k127_2185896_14 RNase H - - - 0.000000000000000000000000000567 123.0
TH1_k127_2185896_15 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000199 105.0
TH1_k127_2185896_16 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000003934 102.0
TH1_k127_2185896_17 PFAM Rubredoxin-type Fe(Cys)4 protein K05297 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0017144,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114,GO:0072592 1.18.1.1 0.00000000000000000000006344 98.0
TH1_k127_2185896_18 NusG domain II K00805 - 2.5.1.30 0.00000000000000000007335 93.0
TH1_k127_2185896_19 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000008889 72.0
TH1_k127_2185896_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 365.0
TH1_k127_2185896_20 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.0000000000003664 79.0
TH1_k127_2185896_21 - - - - 0.0000000000004809 71.0
TH1_k127_2185896_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 356.0
TH1_k127_2185896_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000309 247.0
TH1_k127_2185896_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000001426 253.0
TH1_k127_2185896_6 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000009987 244.0
TH1_k127_2185896_7 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.000000000000000000000000000000000000000000000000000000002131 207.0
TH1_k127_2185896_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000002892 187.0
TH1_k127_2185896_9 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000000006831 177.0
TH1_k127_219738_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 346.0
TH1_k127_219738_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003087 275.0
TH1_k127_219738_2 - - - - 0.0000000000000000000000000000000000000005747 158.0
TH1_k127_219738_3 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.000000000000000000000000000000003694 132.0
TH1_k127_219738_4 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000005244 99.0
TH1_k127_219738_5 S4 domain K14761 - - 0.000000000000000005855 85.0
TH1_k127_2222638_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 538.0
TH1_k127_2222638_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 520.0
TH1_k127_2222638_2 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 503.0
TH1_k127_2222638_3 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002929 272.0
TH1_k127_2222638_4 serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000001524 263.0
TH1_k127_2222638_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000001066 207.0
TH1_k127_2222638_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000108 200.0
TH1_k127_2222638_7 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000007595 203.0
TH1_k127_2222638_8 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.00000000000000001329 87.0
TH1_k127_2253415_0 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 384.0
TH1_k127_2253415_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 357.0
TH1_k127_2253415_2 Uncharacterised nucleotidyltransferase - - - 0.000000003976 65.0
TH1_k127_2253415_3 EamA-like transporter family - - - 0.0007058 43.0
TH1_k127_2257519_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1725.0
TH1_k127_2257519_1 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 543.0
TH1_k127_2257519_10 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000486 124.0
TH1_k127_2257519_11 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000007822 96.0
TH1_k127_2257519_12 Histidine kinase - - - 0.00000000004981 67.0
TH1_k127_2257519_13 - - - - 0.000000002906 61.0
TH1_k127_2257519_14 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000003533 64.0
TH1_k127_2257519_15 Protein involved in outer membrane biogenesis - - - 0.00007756 55.0
TH1_k127_2257519_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 548.0
TH1_k127_2257519_3 PFAM phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 537.0
TH1_k127_2257519_4 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 515.0
TH1_k127_2257519_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 482.0
TH1_k127_2257519_6 membrane K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 366.0
TH1_k127_2257519_7 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000004294 200.0
TH1_k127_2257519_8 protein with SCP PR1 domains - - - 0.000000000000000000000000000000000000000000759 170.0
TH1_k127_2257519_9 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000002296 150.0
TH1_k127_23788_0 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 6.697e-196 617.0
TH1_k127_23788_1 FAD binding domain K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 452.0
TH1_k127_23788_2 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000004369 236.0
TH1_k127_23788_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000006897 113.0
TH1_k127_2440991_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 606.0
TH1_k127_2440991_1 B3/4 domain K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 565.0
TH1_k127_2440991_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 460.0
TH1_k127_2440991_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 316.0
TH1_k127_2440991_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000001395 194.0
TH1_k127_2440991_5 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000002219 122.0
TH1_k127_2440991_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000001629 119.0
TH1_k127_2440991_7 mercury ion transmembrane transporter activity K07213 - - 0.0000000000004592 72.0
TH1_k127_2544884_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1068.0
TH1_k127_2544884_1 FAD dependent oxidoreductase K07137 - - 1.149e-246 771.0
TH1_k127_2544884_10 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002806 237.0
TH1_k127_2544884_11 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000001258 203.0
TH1_k127_2544884_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000002553 176.0
TH1_k127_2544884_13 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide K01480 - 3.5.3.11 0.00000000000000000000000000000000000001648 147.0
TH1_k127_2544884_14 - - - - 0.0000000000000000000000000000000000001372 148.0
TH1_k127_2544884_15 Histidine kinase K02030 - - 0.0000000000000000000000000000000001664 138.0
TH1_k127_2544884_16 ECF sigma factor K03088 - - 0.000000000000000000000000000000000732 138.0
TH1_k127_2544884_17 Domain of unknown function (DUF4349) - - - 0.00004764 52.0
TH1_k127_2544884_18 Protein of unknown function (DUF3106) - - - 0.00004862 52.0
TH1_k127_2544884_19 - - - - 0.0002039 47.0
TH1_k127_2544884_2 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 551.0
TH1_k127_2544884_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 543.0
TH1_k127_2544884_4 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 527.0
TH1_k127_2544884_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 382.0
TH1_k127_2544884_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 347.0
TH1_k127_2544884_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 292.0
TH1_k127_2544884_8 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 282.0
TH1_k127_2544884_9 iron-sulfur transferase activity K07126,K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003148 266.0
TH1_k127_2552179_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1101.0
TH1_k127_2552179_1 CAAX prenyl protease N-terminal, five membrane helices - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 469.0
TH1_k127_2552179_10 - - - - 0.000000000002197 68.0
TH1_k127_2552179_11 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000003885 64.0
TH1_k127_2552179_12 Carboxymuconolactone decarboxylase family - - - 0.0000000004214 66.0
TH1_k127_2552179_13 Alternative oxidase - - - 0.0000000004351 64.0
TH1_k127_2552179_2 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 459.0
TH1_k127_2552179_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 434.0
TH1_k127_2552179_4 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 327.0
TH1_k127_2552179_5 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000504 227.0
TH1_k127_2552179_6 Alternative oxidase - - - 0.0000000000000000000000000000000000001305 142.0
TH1_k127_2552179_7 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.00000000000000000000000000000005272 128.0
TH1_k127_2552179_9 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000006438 82.0
TH1_k127_2568661_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 548.0
TH1_k127_2568661_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 445.0
TH1_k127_2568661_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 336.0
TH1_k127_2601864_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 346.0
TH1_k127_2601864_1 Protoporphyrinogen oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 313.0
TH1_k127_2657376_0 Molybdenum Cofactor Synthesis C K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009562 354.0
TH1_k127_2657376_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002024 247.0
TH1_k127_2657376_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0034214,GO:0042802,GO:0043170,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0061799,GO:0065003,GO:0071704,GO:0071840,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.00000000000000000000000000000000000000000000000000000002373 201.0
TH1_k127_2657376_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000008079 167.0
TH1_k127_2657376_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000002579 121.0
TH1_k127_2657376_5 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000004722 93.0
TH1_k127_2657376_6 DnaJ molecular chaperone homology domain - - - 0.0003092 49.0
TH1_k127_2703581_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 8.563e-280 876.0
TH1_k127_2703581_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 426.0
TH1_k127_2703581_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000009651 202.0
TH1_k127_2703581_11 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000001439 200.0
TH1_k127_2703581_12 DoxX K15977 - - 0.00000000000000000000000000000000000000002531 157.0
TH1_k127_2703581_13 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000001009 130.0
TH1_k127_2703581_15 DEAD DEAH box helicase K05592 - 3.6.4.13 0.00000000000000003421 87.0
TH1_k127_2703581_16 Universal stress protein family - - - 0.0000000000322 70.0
TH1_k127_2703581_17 Protein of unknown function (DUF3592) - - - 0.0000000001383 72.0
TH1_k127_2703581_18 AMP binding - - - 0.0000007428 58.0
TH1_k127_2703581_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 416.0
TH1_k127_2703581_20 Psort location Cytoplasmic, score - - - 0.00003554 49.0
TH1_k127_2703581_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 406.0
TH1_k127_2703581_4 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 387.0
TH1_k127_2703581_5 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 372.0
TH1_k127_2703581_6 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 319.0
TH1_k127_2703581_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000006871 244.0
TH1_k127_2703581_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000001706 202.0
TH1_k127_2703581_9 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000001973 211.0
TH1_k127_2716487_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.123e-305 949.0
TH1_k127_2716487_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 3.503e-249 778.0
TH1_k127_2716487_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 605.0
TH1_k127_2716487_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 504.0
TH1_k127_2716487_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 405.0
TH1_k127_2716487_5 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 387.0
TH1_k127_2716487_6 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001165 243.0
TH1_k127_2716487_7 response regulator - - - 0.00000000000000000000000000000000005735 146.0
TH1_k127_2716487_9 Translation initiation factor SUI1 K03113 - - 0.000000000000000000005264 97.0
TH1_k127_2817003_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 497.0
TH1_k127_2817003_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 456.0
TH1_k127_2817003_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 392.0
TH1_k127_2817003_3 FAD binding domain K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 352.0
TH1_k127_2817003_4 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 349.0
TH1_k127_2817003_5 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 302.0
TH1_k127_2817003_6 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 284.0
TH1_k127_2817003_7 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000006962 233.0
TH1_k127_2817003_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000002148 160.0
TH1_k127_2817003_9 Domain of unknown function (DUF386) - - - 0.00000000000000000000000000000005312 130.0
TH1_k127_281967_0 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000001018 159.0
TH1_k127_281967_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000001803 62.0
TH1_k127_281967_2 protein N-acetylglucosaminyltransferase activity - GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 - 0.00002989 57.0
TH1_k127_2829621_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001589 287.0
TH1_k127_2829621_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000006346 231.0
TH1_k127_2848569_0 lipoprotein localization to outer membrane K02004,K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 462.0
TH1_k127_2848569_1 lipoprotein transporter activity K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 296.0
TH1_k127_2848569_2 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008019 276.0
TH1_k127_2848569_3 - - - - 0.0000000000000000000000000000000000000000000001377 172.0
TH1_k127_2848569_4 - - - - 0.0000000000000000000000001193 111.0
TH1_k127_2848569_5 Transcription factor zinc-finger K09981 - - 0.000000000001779 67.0
TH1_k127_2858922_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 576.0
TH1_k127_2858922_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 467.0
TH1_k127_2858922_10 Protein of unknown function DUF134 - - - 0.0000000000000000118 84.0
TH1_k127_2858922_11 Transposase - - - 0.000000000002196 67.0
TH1_k127_2858922_12 PFAM DsrE DsrF-like family - - - 0.0000000005706 65.0
TH1_k127_2858922_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 421.0
TH1_k127_2858922_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000257 250.0
TH1_k127_2858922_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000003713 201.0
TH1_k127_2858922_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000002094 177.0
TH1_k127_2858922_6 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000001837 171.0
TH1_k127_2858922_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000007078 169.0
TH1_k127_2858922_8 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.000000000000000000000000000000000000001808 150.0
TH1_k127_2858922_9 Member of a two-component regulatory system K07644 - 2.7.13.3 0.00000000000000000000000000003466 131.0
TH1_k127_2944812_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 419.0
TH1_k127_2944812_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 339.0
TH1_k127_2944812_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000642 236.0
TH1_k127_2944812_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000005109 246.0
TH1_k127_2944812_4 SMART HNH nuclease K07451 - - 0.00000000000000000000000000000000000006019 144.0
TH1_k127_2944812_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000012 125.0
TH1_k127_2944812_6 Protein of unknown function (DUF507) - - - 0.000000000000000000000000002716 113.0
TH1_k127_2944812_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000005774 109.0
TH1_k127_2944812_8 Protein of unknown function (DUF507) - - - 0.0000000000000000000002454 100.0
TH1_k127_2944812_9 Single-strand binding protein family K03111 - - 0.0000000000000009893 78.0
TH1_k127_2955092_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.875e-270 847.0
TH1_k127_2955092_1 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 409.0
TH1_k127_2955092_2 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 372.0
TH1_k127_2955092_3 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 287.0
TH1_k127_2955092_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001793 243.0
TH1_k127_2955092_5 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000000001483 190.0
TH1_k127_2955092_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000000001048 172.0
TH1_k127_2955092_7 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000001005 143.0
TH1_k127_2955092_8 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000001535 111.0
TH1_k127_3057139_0 Heat shock 70 kDa protein K04043 - - 1.055e-318 985.0
TH1_k127_3057139_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.239e-223 698.0
TH1_k127_3057139_10 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000006811 175.0
TH1_k127_3057139_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000005171 156.0
TH1_k127_3057139_12 Chromate transporter K07240 - - 0.00000000000000000000000000000001423 134.0
TH1_k127_3057139_13 Chromate transporter K07240 - - 0.000000000000000000000000000004868 126.0
TH1_k127_3057139_14 PFAM aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000003432 117.0
TH1_k127_3057139_15 membrane K07058 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000001959 95.0
TH1_k127_3057139_16 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.000000000004866 66.0
TH1_k127_3057139_2 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 502.0
TH1_k127_3057139_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 439.0
TH1_k127_3057139_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 410.0
TH1_k127_3057139_5 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 370.0
TH1_k127_3057139_6 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 299.0
TH1_k127_3057139_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000002672 244.0
TH1_k127_3057139_8 retrograde transport, endosome to Golgi K07095 - - 0.000000000000000000000000000000000000000000000000001418 186.0
TH1_k127_3057139_9 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000004207 187.0
TH1_k127_3083390_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 573.0
TH1_k127_3083390_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 481.0
TH1_k127_3083390_10 energy transducer activity K03646,K03832 - - 0.0000000000000002148 88.0
TH1_k127_3083390_11 - - - - 0.000000000000002616 78.0
TH1_k127_3083390_12 GIY-YIG catalytic domain K07461 - - 0.00000000000001721 79.0
TH1_k127_3083390_14 Transcriptional regulators - - - 0.00001221 48.0
TH1_k127_3083390_15 Glyoxalase-like domain K06996 - - 0.0001086 45.0
TH1_k127_3083390_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 320.0
TH1_k127_3083390_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002219 277.0
TH1_k127_3083390_4 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001078 276.0
TH1_k127_3083390_5 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000003631 194.0
TH1_k127_3083390_6 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000006684 145.0
TH1_k127_3083390_7 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000003251 153.0
TH1_k127_3083390_8 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000448 148.0
TH1_k127_3083390_9 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000003776 89.0
TH1_k127_3152811_0 PD-(D/E)XK nuclease superfamily - - - 3.614e-234 760.0
TH1_k127_3152811_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 323.0
TH1_k127_3152811_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002314 243.0
TH1_k127_3152811_3 - - - - 0.0000000000000000000000000000000000000000000001457 173.0
TH1_k127_3152811_4 PIN domain - - - 0.000000000000000000000000000000000002553 141.0
TH1_k127_3152811_6 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000002009 77.0
TH1_k127_316326_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.908e-197 625.0
TH1_k127_316326_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 577.0
TH1_k127_316326_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 481.0
TH1_k127_316326_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 481.0
TH1_k127_316326_4 Glycosyl transferase, family 2 K12992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 383.0
TH1_k127_316326_5 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 384.0
TH1_k127_316326_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 328.0
TH1_k127_316326_7 general secretion pathway protein K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000007831 81.0
TH1_k127_316326_8 SMART helix-turn-helix domain protein K15539 - - 0.0000000001619 71.0
TH1_k127_316326_9 heat shock protein binding K03686 - - 0.00000009018 65.0
TH1_k127_3186718_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.44e-276 865.0
TH1_k127_3186718_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 529.0
TH1_k127_3186718_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 374.0
TH1_k127_3186718_3 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.000000000000000000000000000000000000002323 152.0
TH1_k127_3186718_4 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000009526 110.0
TH1_k127_3225506_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 623.0
TH1_k127_3225506_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 337.0
TH1_k127_3225506_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 308.0
TH1_k127_3225506_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000002069 227.0
TH1_k127_3225506_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003446 225.0
TH1_k127_3230881_0 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 327.0
TH1_k127_3230881_1 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000001932 212.0
TH1_k127_3230881_2 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000001438 187.0
TH1_k127_3230881_3 Ribbon-helix-helix protein, copG family - - - 0.000000000000000000001678 96.0
TH1_k127_3230881_4 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0001233 46.0
TH1_k127_3327588_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008186 416.0
TH1_k127_3327588_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 386.0
TH1_k127_3327588_2 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000002364 91.0
TH1_k127_3395051_0 ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008744 292.0
TH1_k127_3395051_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002666 243.0
TH1_k127_3395051_2 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000004356 192.0
TH1_k127_3395051_3 response regulator K02485 - - 0.000000000000000000000000000000000000000000000000000268 188.0
TH1_k127_3395051_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000003435 117.0
TH1_k127_3474027_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 578.0
TH1_k127_3474027_1 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 405.0
TH1_k127_3474027_2 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 303.0
TH1_k127_3474027_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 298.0
TH1_k127_3474027_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000616 229.0
TH1_k127_3474027_5 His Kinase A (phosphoacceptor) domain K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000006958 194.0
TH1_k127_3474027_6 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000894 174.0
TH1_k127_3515109_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1094.0
TH1_k127_3515109_1 Surface antigen K07277 - - 1.121e-247 786.0
TH1_k127_3515109_10 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000003366 213.0
TH1_k127_3515109_11 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000002713 197.0
TH1_k127_3515109_12 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000001559 152.0
TH1_k127_3515109_13 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.00000000000000000000000008521 113.0
TH1_k127_3515109_14 Addiction module toxin, RelE StbE - - - 0.000000000000000000001022 97.0
TH1_k127_3515109_15 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000149 79.0
TH1_k127_3515109_16 Ribbon-helix-helix protein, copG family - - - 0.0000000000001398 74.0
TH1_k127_3515109_2 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 607.0
TH1_k127_3515109_3 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 595.0
TH1_k127_3515109_4 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 548.0
TH1_k127_3515109_5 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 549.0
TH1_k127_3515109_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 375.0
TH1_k127_3515109_7 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 364.0
TH1_k127_3515109_8 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 293.0
TH1_k127_3515109_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000007388 244.0
TH1_k127_3664103_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 330.0
TH1_k127_3664103_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002551 276.0
TH1_k127_3664103_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000008688 176.0
TH1_k127_3664103_3 energy transducer activity K03832 - - 0.00000000000000000000000000000000000000003768 163.0
TH1_k127_3664103_4 Universal stress protein family - - - 0.0000000000000000000000000000000000001856 147.0
TH1_k127_3664103_5 alpha beta - - - 0.00000000000000000000000000000000002206 147.0
TH1_k127_3664103_6 proteolysis K03665 - - 0.00000000000000000000000001158 116.0
TH1_k127_3670455_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.904e-263 823.0
TH1_k127_3670455_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.073e-215 674.0
TH1_k127_3670455_2 DEAD DEAH box helicase K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 464.0
TH1_k127_3670455_3 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 319.0
TH1_k127_3670455_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000009482 229.0
TH1_k127_3670455_5 ACT domain - - - 0.00000000000000000000000000000000000000000000000000003492 190.0
TH1_k127_3670455_6 protein-disulfide reductase activity - - - 0.00000000000000000000001905 105.0
TH1_k127_3701230_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.875e-280 884.0
TH1_k127_3701230_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.378e-265 843.0
TH1_k127_3701230_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000003695 142.0
TH1_k127_3701230_11 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000002076 101.0
TH1_k127_3701230_12 peptidyl-tyrosine sulfation - - - 0.000000000000000000004836 101.0
TH1_k127_3701230_13 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000008002 93.0
TH1_k127_3701230_14 Protein of unknown function (DUF721) - - - 0.000000008142 63.0
TH1_k127_3701230_15 Domain of unknown function (DUF4912) K09942 - - 0.000007929 58.0
TH1_k127_3701230_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 575.0
TH1_k127_3701230_3 Transport of potassium into the cell K03549 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 535.0
TH1_k127_3701230_4 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 344.0
TH1_k127_3701230_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 329.0
TH1_k127_3701230_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006961 276.0
TH1_k127_3701230_7 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000173 261.0
TH1_k127_3701230_8 tRNA pseudouridylate synthase B C-terminal domain K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000004332 241.0
TH1_k127_3701230_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000006536 234.0
TH1_k127_3837778_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000001709 189.0
TH1_k127_3837778_1 Protein export membrane protein K07003 - - 0.000000000000000000000000000000000000000000000000002785 207.0
TH1_k127_3837778_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000002995 98.0
TH1_k127_3837778_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000004177 84.0
TH1_k127_3837778_4 PFAM Glycosyl transferase family 2 - - - 0.000000000000005861 76.0
TH1_k127_3867455_0 O-Antigen ligase K02847 - - 0.00000000000000000000000000000000000000000000000000008554 204.0
TH1_k127_3867455_1 PFAM PHP domain protein K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000002213 184.0
TH1_k127_3867455_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000001455 190.0
TH1_k127_3867455_3 KOW (Kyprides, Ouzounis, Woese) motif. K05785 - - 0.00000000000000000000000000000002607 131.0
TH1_k127_3867455_4 DNA-binding transcription factor activity K18996 - - 0.00000000000000000000000000158 114.0
TH1_k127_3867455_5 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000005589 90.0
TH1_k127_3867455_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000005129 72.0
TH1_k127_3908590_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 389.0
TH1_k127_3908590_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000001841 130.0
TH1_k127_3908590_2 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.00005622 48.0
TH1_k127_3908590_3 Biotin-protein ligase, N terminal - - - 0.00006289 46.0
TH1_k127_391457_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1504.0
TH1_k127_391457_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.839e-265 833.0
TH1_k127_391457_10 Belongs to the 'phage' integrase family - - - 0.00000000003497 68.0
TH1_k127_391457_11 protein transport across the cell outer membrane K02246,K02457,K02459,K02672,K08084 - - 0.00000000379 66.0
TH1_k127_391457_12 Pfam:N_methyl_2 K02459 - - 0.000001849 57.0
TH1_k127_391457_2 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 554.0
TH1_k127_391457_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 372.0
TH1_k127_391457_4 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 342.0
TH1_k127_391457_5 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 299.0
TH1_k127_391457_6 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002141 242.0
TH1_k127_391457_7 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000001762 230.0
TH1_k127_391457_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000001113 198.0
TH1_k127_391457_9 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000000000000009464 187.0
TH1_k127_3919843_0 glycolate transport K14393 - - 8.359e-234 736.0
TH1_k127_3919843_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 1.402e-223 709.0
TH1_k127_3919843_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000005072 133.0
TH1_k127_3919843_3 Protein of unknown function, DUF485 - - - 0.0000000000000000000000005133 107.0
TH1_k127_3919843_4 - - - - 0.0000004618 53.0
TH1_k127_3940501_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.291e-297 933.0
TH1_k127_3940501_1 C-terminal, D2-small domain, of ClpB protein K03694 - - 8.726e-281 881.0
TH1_k127_3940501_10 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007697 292.0
TH1_k127_3940501_11 Male sterility protein K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008886 271.0
TH1_k127_3940501_12 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000004903 226.0
TH1_k127_3940501_13 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000002458 181.0
TH1_k127_3940501_14 - - - - 0.00000000000000000000000000000000000000009619 173.0
TH1_k127_3940501_15 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.000000000000000000000000000003703 122.0
TH1_k127_3940501_16 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000002274 132.0
TH1_k127_3940501_17 DUF218 domain - - - 0.0000000000002006 79.0
TH1_k127_3940501_18 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.0000000001329 64.0
TH1_k127_3940501_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.217e-199 625.0
TH1_k127_3940501_3 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 607.0
TH1_k127_3940501_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 409.0
TH1_k127_3940501_5 cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 391.0
TH1_k127_3940501_6 PFAM Class II aldolase K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 357.0
TH1_k127_3940501_7 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 336.0
TH1_k127_3940501_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 320.0
TH1_k127_3940501_9 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003759 276.0
TH1_k127_3947728_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 302.0
TH1_k127_3947728_1 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001311 235.0
TH1_k127_3947728_2 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000007997 82.0
TH1_k127_3947728_3 metalloendopeptidase activity K08602 - - 0.0008496 48.0
TH1_k127_3990627_0 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 473.0
TH1_k127_3990627_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000156 206.0
TH1_k127_3991267_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 306.0
TH1_k127_3991267_1 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001311 241.0
TH1_k127_3991267_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000001786 221.0
TH1_k127_3991267_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000001003 121.0
TH1_k127_3997263_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 2.016e-198 639.0
TH1_k127_3997263_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 353.0
TH1_k127_3997263_2 HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide K12138,K12139,K15829 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 300.0
TH1_k127_3997263_3 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000003385 220.0
TH1_k127_3997263_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000000000000000002885 158.0
TH1_k127_3997263_5 - - - - 0.00000000000000000000000000000000004248 137.0
TH1_k127_3997263_6 Helix-turn-helix domain K02806 - - 0.000000000000000000000000000000001332 138.0
TH1_k127_3997263_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.000003373 51.0
TH1_k127_4021473_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.296e-264 831.0
TH1_k127_4021473_1 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 576.0
TH1_k127_4021473_2 DHH family K07462 - - 0.0000000000000000000001212 100.0
TH1_k127_4021496_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.301e-226 713.0
TH1_k127_4021496_1 DHH family K07462 - - 0.000000000000000000000001988 106.0
TH1_k127_4170310_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 537.0
TH1_k127_4170310_1 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 414.0
TH1_k127_4170310_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 316.0
TH1_k127_4170310_3 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000008323 243.0
TH1_k127_4170310_4 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000004474 173.0
TH1_k127_4170310_5 MgtC family K07507 - - 0.0000000000000000000000002302 111.0
TH1_k127_4170310_6 - - - - 0.00000000000000000000376 96.0
TH1_k127_4178495_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 405.0
TH1_k127_4178495_1 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001189 253.0
TH1_k127_4178495_2 SagB-type dehydrogenase domain - - - 0.0000000000000000000000004058 108.0
TH1_k127_4191522_0 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000004517 191.0
TH1_k127_4347252_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1321.0
TH1_k127_4347252_1 Belongs to the Fur family K03711,K09825 - - 0.00000000000000000000000000000000000000000000000894 174.0
TH1_k127_4347252_2 Bacterial regulatory proteins, crp family - - - 0.00000000000000000000000000000000000000009638 154.0
TH1_k127_4347252_3 - - - - 0.00000000000000000000000000000000000000009979 154.0
TH1_k127_4347252_4 amino acid K03294 - - 0.0004034 51.0
TH1_k127_4372112_0 Major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598 371.0
TH1_k127_4372112_1 TIGRFAM PAS domain S-box - - - 0.0000000000000000000000000000000000000000000002598 184.0
TH1_k127_4477369_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 5.058e-282 890.0
TH1_k127_4477369_1 Glycosyl hydrolase family 57 - - - 1.564e-239 762.0
TH1_k127_4477369_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 471.0
TH1_k127_4477369_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000147 174.0
TH1_k127_4477369_4 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000002696 158.0
TH1_k127_4477369_5 - - - - 0.0000000000000000000002231 111.0
TH1_k127_4477369_6 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000001576 74.0
TH1_k127_4477369_7 cell cycle K05589,K12065,K13052 - - 0.0000000000001043 74.0
TH1_k127_458275_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 410.0
TH1_k127_458275_1 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 339.0
TH1_k127_458275_2 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 327.0
TH1_k127_458275_3 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000003258 203.0
TH1_k127_458275_4 Domain of unknown function (DUF4388) - - - 0.0000000000000000000001126 110.0
TH1_k127_458275_5 DnaJ molecular chaperone homology domain - - - 0.000002731 59.0
TH1_k127_4607107_0 Endoribonuclease that initiates mRNA decay K18682 - - 6.69e-208 658.0
TH1_k127_4607107_1 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 564.0
TH1_k127_4607107_10 Bacterial type II and III secretion system protein K02453,K03219 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 336.0
TH1_k127_4607107_11 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 315.0
TH1_k127_4607107_12 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 297.0
TH1_k127_4607107_13 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003534 275.0
TH1_k127_4607107_14 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000216 245.0
TH1_k127_4607107_15 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000384 214.0
TH1_k127_4607107_16 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000588 198.0
TH1_k127_4607107_17 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000007502 130.0
TH1_k127_4607107_18 PFAM response regulator receiver - - - 0.00000000000000000000000000001398 123.0
TH1_k127_4607107_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000001093 90.0
TH1_k127_4607107_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 552.0
TH1_k127_4607107_20 diguanylate cyclase (GGDEF) domain - - - 0.0000000000000004885 93.0
TH1_k127_4607107_21 Fimbrial assembly protein (PilN) K02461 - - 0.00000000000205 79.0
TH1_k127_4607107_3 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 511.0
TH1_k127_4607107_4 AAA ATPase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 466.0
TH1_k127_4607107_5 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 463.0
TH1_k127_4607107_6 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 443.0
TH1_k127_4607107_7 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 359.0
TH1_k127_4607107_8 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 331.0
TH1_k127_4607107_9 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 323.0
TH1_k127_4655255_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 5.968e-298 926.0
TH1_k127_4655255_1 CO-methylating acetyl-CoA synthase activity K00193,K14138 - 2.3.1.169 2.201e-266 839.0
TH1_k127_4655255_2 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 585.0
TH1_k127_4655255_3 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 500.0
TH1_k127_4655255_4 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 374.0
TH1_k127_4655255_5 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 356.0
TH1_k127_4655255_6 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 352.0
TH1_k127_4655255_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000401 124.0
TH1_k127_4707263_0 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 430.0
TH1_k127_4707263_1 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 362.0
TH1_k127_4707263_2 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 322.0
TH1_k127_4707263_3 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 301.0
TH1_k127_4707263_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001283 283.0
TH1_k127_4707263_5 type II III secretion system K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006979 283.0
TH1_k127_4707263_6 TIGRFAM iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000000000004285 182.0
TH1_k127_4707263_7 PFAM Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000000001696 152.0
TH1_k127_4707263_8 Tetratricopeptide repeat - - - 0.0000002489 60.0
TH1_k127_4707263_9 phosphorelay signal transduction system - - - 0.0004734 47.0
TH1_k127_4707591_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1116.0
TH1_k127_4707591_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 534.0
TH1_k127_4707591_10 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000001383 76.0
TH1_k127_4707591_11 - - - - 0.000000002177 59.0
TH1_k127_4707591_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 520.0
TH1_k127_4707591_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 383.0
TH1_k127_4707591_4 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 396.0
TH1_k127_4707591_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 331.0
TH1_k127_4707591_6 YbbR-like protein - - - 0.00000000000000000000000000000000000000004053 159.0
TH1_k127_4707591_7 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000006021 158.0
TH1_k127_4707591_8 cytochrome complex assembly K02200,K04018 - - 0.0000000000000000000000000005564 120.0
TH1_k127_4790790_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 6.104e-278 866.0
TH1_k127_4790790_1 Ami_2 K01447 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
TH1_k127_4790790_2 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000005911 216.0
TH1_k127_4790790_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000009361 186.0
TH1_k127_4790790_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000003961 176.0
TH1_k127_4790790_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000001202 144.0
TH1_k127_4790790_6 Rhodanese Homology Domain - - - 0.0000000000000000000000000000002824 137.0
TH1_k127_4790790_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000003645 91.0
TH1_k127_4790790_8 Universal stress protein - - - 0.0000004963 58.0
TH1_k127_4867195_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 500.0
TH1_k127_4867195_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 308.0
TH1_k127_4867195_10 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000192 114.0
TH1_k127_4867195_11 LysM domain - - - 0.00000000493 69.0
TH1_k127_4867195_12 Tetratricopeptide repeats - - - 0.00002825 56.0
TH1_k127_4867195_13 Outer membrane lipoprotein - - - 0.0003438 54.0
TH1_k127_4867195_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000166 220.0
TH1_k127_4867195_3 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000003713 199.0
TH1_k127_4867195_4 - - - - 0.00000000000000000000000000000000000000000000000000004267 210.0
TH1_k127_4867195_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000002538 192.0
TH1_k127_4867195_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000001053 149.0
TH1_k127_4867195_7 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000004828 136.0
TH1_k127_4867195_8 protein family UPF0079, ATPase K06925 - - 0.000000000000000000000000001834 116.0
TH1_k127_4867195_9 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000008996 110.0
TH1_k127_4873010_0 Putative Fe-S cluster K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 341.0
TH1_k127_4873010_1 Transcriptional regulatory protein, C terminal K07664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 283.0
TH1_k127_4873010_2 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000005315 233.0
TH1_k127_4873010_3 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000006361 199.0
TH1_k127_4873010_4 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00005518 49.0
TH1_k127_4883850_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 9.138e-286 893.0
TH1_k127_4883850_1 Psort location Cytoplasmic, score K07137 - - 2.879e-217 684.0
TH1_k127_4883850_10 electron transfer activity K05337,K17247 - - 0.0000001812 54.0
TH1_k127_4883850_11 - - - - 0.000006978 48.0
TH1_k127_4883850_2 metal ion transmembrane transporter activity K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 570.0
TH1_k127_4883850_3 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 566.0
TH1_k127_4883850_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 496.0
TH1_k127_4883850_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 409.0
TH1_k127_4883850_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000009666 258.0
TH1_k127_4883850_7 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000002189 207.0
TH1_k127_4883850_8 TIGRFAM 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000000000000000000001082 116.0
TH1_k127_4883850_9 Glutamine amidotransferase class-I - - - 0.0000000003617 63.0
TH1_k127_4887216_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 574.0
TH1_k127_4887216_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 443.0
TH1_k127_4887216_10 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000001273 55.0
TH1_k127_4887216_11 - - - - 0.000001412 49.0
TH1_k127_4887216_2 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001728 279.0
TH1_k127_4887216_3 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001092 271.0
TH1_k127_4887216_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000002304 212.0
TH1_k127_4887216_5 - - - - 0.00000000000000000000000000000000000000000000000000000001623 206.0
TH1_k127_4887216_6 - - - - 0.00000000000000000006358 90.0
TH1_k127_4887216_7 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000001479 78.0
TH1_k127_4887216_8 Thiamine biosynthesis K03154 - - 0.000000000001865 70.0
TH1_k127_4887216_9 Permease MlaE K02066 - - 0.0000000001483 63.0
TH1_k127_4908620_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 520.0
TH1_k127_4908620_1 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 446.0
TH1_k127_4908620_10 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 291.0
TH1_k127_4908620_11 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000324 278.0
TH1_k127_4908620_12 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 265.0
TH1_k127_4908620_13 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000000019 230.0
TH1_k127_4908620_14 Polypeptide deformylase K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000003156 209.0
TH1_k127_4908620_15 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000004327 163.0
TH1_k127_4908620_16 Radical SAM superfamily K04070 - 1.97.1.4 0.0000000000000000000000000000000000002441 146.0
TH1_k127_4908620_17 PIN domain K07063 - - 0.0000000000000000000000000000000001259 137.0
TH1_k127_4908620_18 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000005165 131.0
TH1_k127_4908620_19 OstA-like protein K09774 - - 0.0000000000000000000000000000002393 129.0
TH1_k127_4908620_2 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 416.0
TH1_k127_4908620_20 SMART Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.0000000000000000000000000001415 119.0
TH1_k127_4908620_21 mRNA binding K07339 - - 0.0000000000000000000000005055 104.0
TH1_k127_4908620_22 Plasmid stabilization system - - - 0.000000000000000000000005414 102.0
TH1_k127_4908620_23 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000001569 98.0
TH1_k127_4908620_24 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000006038 85.0
TH1_k127_4908620_25 - - - - 0.0000000000000008836 79.0
TH1_k127_4908620_26 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000001284 86.0
TH1_k127_4908620_27 - - - - 0.00000000000006527 74.0
TH1_k127_4908620_28 bacterial-type flagellum-dependent cell motility - - - 0.00000000006326 69.0
TH1_k127_4908620_29 peptidyl-tyrosine sulfation - - - 0.00000000009607 71.0
TH1_k127_4908620_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 407.0
TH1_k127_4908620_30 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000002744 61.0
TH1_k127_4908620_31 - - - - 0.0000002183 61.0
TH1_k127_4908620_32 Putative addiction module component - - - 0.00002533 48.0
TH1_k127_4908620_33 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.00005163 52.0
TH1_k127_4908620_4 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 366.0
TH1_k127_4908620_5 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 367.0
TH1_k127_4908620_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 321.0
TH1_k127_4908620_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 320.0
TH1_k127_4908620_8 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 316.0
TH1_k127_4908620_9 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 302.0
TH1_k127_4917409_0 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 9.382e-216 682.0
TH1_k127_4917409_1 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 499.0
TH1_k127_4917409_2 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002317 280.0
TH1_k127_4917409_3 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000001728 236.0
TH1_k127_4917409_4 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000002494 229.0
TH1_k127_4917409_5 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000001379 217.0
TH1_k127_4917409_6 Peptidase S24-like K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000005743 210.0
TH1_k127_4917409_7 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000006123 130.0
TH1_k127_4917409_8 - - - - 0.000000000000000000000001119 109.0
TH1_k127_4917409_9 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000006007 81.0
TH1_k127_4988698_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 8.355e-234 730.0
TH1_k127_4988698_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 593.0
TH1_k127_4988698_2 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000143 246.0
TH1_k127_4988698_3 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000009661 234.0
TH1_k127_4988698_4 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000001291 184.0
TH1_k127_4988698_5 Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000002717 188.0
TH1_k127_4988698_6 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000009297 144.0
TH1_k127_4988698_7 Gaf domain K02488 - 2.7.7.65 0.000000000000000000000000000000004173 132.0
TH1_k127_4988698_8 RNA-binding protein - - - 0.000000000000000000000006392 104.0
TH1_k127_5054664_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000179 248.0
TH1_k127_5054664_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000004777 207.0
TH1_k127_5054664_2 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000002775 152.0
TH1_k127_5062989_0 PFAM UvrD REP helicase K03656,K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 602.0
TH1_k127_5062989_1 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000005843 231.0
TH1_k127_5062989_2 Protein of unknown function, DUF480 K09915 - - 0.000000000000000000000000000000000000000000000000000000000007908 213.0
TH1_k127_5062989_3 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000001232 147.0
TH1_k127_5062989_4 - - - - 0.0000000000000000401 86.0
TH1_k127_5066873_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1106.0
TH1_k127_5066873_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 402.0
TH1_k127_5066873_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 318.0
TH1_k127_5066873_3 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 299.0
TH1_k127_5066873_4 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000004216 237.0
TH1_k127_5072015_0 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000006934 190.0
TH1_k127_5072015_1 12 heme-binding sites - - - 0.00000000000000000000000000000000000000313 156.0
TH1_k127_5072015_2 denitrification pathway - - - 0.00000000000000000000000000000000002488 147.0
TH1_k127_5074336_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 365.0
TH1_k127_5074336_1 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 302.0
TH1_k127_5074336_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 310.0
TH1_k127_5074336_3 Integrase core domain protein - - - 0.000000000000000000000000000000000000000000000000001675 194.0
TH1_k127_5074336_4 Domain of unknown function (DUF4124) K08309 - - 0.0000000000000000000000000000000000000000000006609 174.0
TH1_k127_5074336_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000005145 136.0
TH1_k127_5074336_6 Putative regulatory protein - - - 0.00000000000000000000001385 103.0
TH1_k127_5098218_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 570.0
TH1_k127_5098218_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 284.0
TH1_k127_5098218_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000009647 203.0
TH1_k127_5098218_3 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000178 163.0
TH1_k127_5135635_0 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 283.0
TH1_k127_5135635_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006657 275.0
TH1_k127_5135635_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001871 273.0
TH1_k127_5135635_3 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.00000000000000000000000007655 110.0
TH1_k127_5135635_4 Cytochrome c K02305 - - 0.00000000003363 68.0
TH1_k127_5162561_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003511 266.0
TH1_k127_5162561_1 IMP dehydrogenase activity - - - 0.0000000000000000000000000000002301 129.0
TH1_k127_5162561_2 response regulator, receiver - - - 0.0000000000000000000000006456 111.0
TH1_k127_5162561_3 Histidine kinase - - - 0.000000000005675 74.0
TH1_k127_5168728_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 5.13e-199 629.0
TH1_k127_5168728_1 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 584.0
TH1_k127_5168728_10 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000003815 184.0
TH1_k127_5168728_11 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000008439 175.0
TH1_k127_5168728_12 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000001481 167.0
TH1_k127_5168728_13 ferredoxin-thioredoxin reductase activity - - - 0.0000000000000000000000000000000000000001197 153.0
TH1_k127_5168728_14 protocatechuate 3,4-dioxygenase - - - 0.0000000000000000000000000000000000000008321 152.0
TH1_k127_5168728_15 HNH nucleases - - - 0.00000000000000000000000000000000000001881 146.0
TH1_k127_5168728_16 - - - - 0.0000000000000000000000000000000000006803 145.0
TH1_k127_5168728_17 PFAM Transglycosylase-associated protein - - - 0.000000000000000000000000000000004838 129.0
TH1_k127_5168728_18 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000001646 124.0
TH1_k127_5168728_19 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.000000000000000000004852 97.0
TH1_k127_5168728_2 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 441.0
TH1_k127_5168728_21 Peptidoglycan-binding LysM - - - 0.0000000000000615 75.0
TH1_k127_5168728_22 - - - - 0.000000000002306 68.0
TH1_k127_5168728_23 - - - - 0.00000000008016 66.0
TH1_k127_5168728_24 Belongs to the pirin family K06911 - - 0.000001624 53.0
TH1_k127_5168728_3 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 422.0
TH1_k127_5168728_4 S1 domain K00243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 341.0
TH1_k127_5168728_5 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 311.0
TH1_k127_5168728_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001659 276.0
TH1_k127_5168728_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000007328 263.0
TH1_k127_5168728_8 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006526 239.0
TH1_k127_5168728_9 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000004136 211.0
TH1_k127_5198686_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 5.198e-237 741.0
TH1_k127_5198686_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 538.0
TH1_k127_5198686_10 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000001954 157.0
TH1_k127_5198686_11 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000001604 129.0
TH1_k127_5198686_12 HupF/HypC family K04653 - - 0.0000000000000000008849 89.0
TH1_k127_5198686_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 477.0
TH1_k127_5198686_3 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 421.0
TH1_k127_5198686_4 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 391.0
TH1_k127_5198686_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 385.0
TH1_k127_5198686_6 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004979 267.0
TH1_k127_5198686_7 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000006038 187.0
TH1_k127_5198686_8 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000976 184.0
TH1_k127_5198686_9 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000000000003197 179.0
TH1_k127_5208237_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.925e-228 717.0
TH1_k127_5208237_1 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 595.0
TH1_k127_5208237_10 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000009939 149.0
TH1_k127_5208237_11 Transcriptional regulator - - - 0.00000000000000000000000000000000000001532 149.0
TH1_k127_5208237_12 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000000000000002956 151.0
TH1_k127_5208237_13 - - - - 0.0000000000000000000000000000000000002366 143.0
TH1_k127_5208237_14 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000003011 147.0
TH1_k127_5208237_15 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000000001016 124.0
TH1_k127_5208237_16 Sulfurtransferase TusA - - - 0.0000000000000000000000002906 106.0
TH1_k127_5208237_17 Glutaredoxin K03676 - - 0.00000000000002401 73.0
TH1_k127_5208237_2 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 535.0
TH1_k127_5208237_3 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 417.0
TH1_k127_5208237_4 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 380.0
TH1_k127_5208237_5 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000005558 234.0
TH1_k127_5208237_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000004241 226.0
TH1_k127_5208237_7 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000007109 194.0
TH1_k127_5208237_8 Dihydroorotate dehydrogenase electron transfer subunit K02823 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0042602,GO:0052875,GO:0055114 - 0.00000000000000000000000000000000000000000000000002853 188.0
TH1_k127_5208237_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000002168 153.0
TH1_k127_5218490_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 5.094e-254 794.0
TH1_k127_5218490_1 Chain length determinant protein K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 618.0
TH1_k127_5218490_10 TIGRFAM molybdenum cofactor synthesis domain - - - 0.00000000000000000000000000000000005057 136.0
TH1_k127_5218490_11 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000005669 117.0
TH1_k127_5218490_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 496.0
TH1_k127_5218490_3 Lipid A core-O-antigen ligase-like enyme K18814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 484.0
TH1_k127_5218490_4 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 400.0
TH1_k127_5218490_5 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 288.0
TH1_k127_5218490_6 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 301.0
TH1_k127_5218490_7 export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008958 284.0
TH1_k127_5218490_8 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000004141 213.0
TH1_k127_5218490_9 Putative beta-barrel porin 2 K20920 - - 0.000000000000000000000000000000000000000009011 175.0
TH1_k127_5229392_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 605.0
TH1_k127_5229392_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 449.0
TH1_k127_5229392_2 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.000000000000000000000000000000000000000000009094 171.0
TH1_k127_5237075_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 513.0
TH1_k127_5237075_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000157 111.0
TH1_k127_5244041_0 4Fe-4S dicluster domain - - - 1.183e-302 933.0
TH1_k127_5244041_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 446.0
TH1_k127_5244041_2 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 421.0
TH1_k127_5244041_3 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000000000000000003358 188.0
TH1_k127_5244041_4 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.0000000000000000000000000000000000000000000001231 174.0
TH1_k127_5244041_5 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000001026 120.0
TH1_k127_5244041_6 lyase activity - - - 0.000000000000004661 80.0
TH1_k127_5291868_0 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 545.0
TH1_k127_5291868_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 452.0
TH1_k127_5291868_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 321.0
TH1_k127_5291868_3 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000006471 218.0
TH1_k127_5310360_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 467.0
TH1_k127_5310360_1 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000002314 176.0
TH1_k127_5310360_2 cheY-homologous receiver domain - - - 0.000000000000000000000000001776 120.0
TH1_k127_5310360_3 Protein of unknown function (DUF1232) - - - 0.000000000000000000000009563 104.0
TH1_k127_5310360_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000002266 81.0
TH1_k127_5310360_5 Histidine kinase K13040 - 2.7.13.3 0.000000001414 65.0
TH1_k127_5310360_7 PilZ domain - - - 0.0004646 47.0
TH1_k127_5327603_0 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000006284 234.0
TH1_k127_5327603_1 PFAM HhH-GPD family protein K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000004817 227.0
TH1_k127_5353047_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 4.128e-254 797.0
TH1_k127_5353047_1 COG2200 FOG EAL domain K20963 - 3.1.4.52 0.00000005056 62.0
TH1_k127_5353047_2 PFAM Methyltransferase type 11 - - - 0.00001053 49.0
TH1_k127_5372756_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 591.0
TH1_k127_5372756_1 Caspase domain - - - 0.00000000000000006576 93.0
TH1_k127_5372756_2 Winged helix-turn helix - - - 0.000000004553 60.0
TH1_k127_5372756_3 COG COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.000003125 59.0
TH1_k127_5372756_4 Domain of unknown function (DUF4384) - - - 0.000007082 57.0
TH1_k127_5372756_5 - - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009507,GO:0009509,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009575,GO:0009579,GO:0009611,GO:0009628,GO:0009642,GO:0009644,GO:0009765,GO:0009941,GO:0009987,GO:0010206,GO:0010207,GO:0015979,GO:0016020,GO:0016043,GO:0019538,GO:0019684,GO:0019898,GO:0022607,GO:0030091,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0034622,GO:0035448,GO:0042170,GO:0042651,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0055035,GO:0065003,GO:0071704,GO:0071840,GO:1901564 - 0.00005156 53.0
TH1_k127_5397370_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 546.0
TH1_k127_5397370_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 391.0
TH1_k127_5397370_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008451 278.0
TH1_k127_5397370_3 Bacterial regulatory helix-turn-helix protein, lysR family K21900 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001851 252.0
TH1_k127_5397370_4 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000001482 226.0
TH1_k127_5397370_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000009348 212.0
TH1_k127_5397370_6 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000001609 133.0
TH1_k127_5397370_7 - - - - 0.0007743 49.0
TH1_k127_5424697_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 604.0
TH1_k127_5424697_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 507.0
TH1_k127_5424697_10 HEAT repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002024 289.0
TH1_k127_5424697_11 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002182 265.0
TH1_k127_5424697_12 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000001986 257.0
TH1_k127_5424697_13 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000004906 206.0
TH1_k127_5424697_14 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000001665 162.0
TH1_k127_5424697_15 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000000000000006912 138.0
TH1_k127_5424697_16 Plasmid stabilization system K19092 - - 0.00000000000000000000000000006685 119.0
TH1_k127_5424697_17 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000008729 123.0
TH1_k127_5424697_18 PBP superfamily domain K02040 - - 0.000000000000000000000000000225 119.0
TH1_k127_5424697_19 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000001328 106.0
TH1_k127_5424697_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 479.0
TH1_k127_5424697_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 445.0
TH1_k127_5424697_4 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 415.0
TH1_k127_5424697_5 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005131 357.0
TH1_k127_5424697_6 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 311.0
TH1_k127_5424697_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 305.0
TH1_k127_5424697_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 309.0
TH1_k127_5424697_9 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009034 287.0
TH1_k127_5431392_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.643e-282 881.0
TH1_k127_5431392_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 8.81e-260 823.0
TH1_k127_5431392_2 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 520.0
TH1_k127_5431392_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 485.0
TH1_k127_5431392_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 394.0
TH1_k127_5431392_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 345.0
TH1_k127_5432246_0 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 544.0
TH1_k127_5432246_1 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 293.0
TH1_k127_5432246_2 Histidine kinase HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000000009165 237.0
TH1_k127_5432246_3 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000004505 210.0
TH1_k127_5432246_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000147 163.0
TH1_k127_5432246_5 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000003052 79.0
TH1_k127_5434008_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 384.0
TH1_k127_5434008_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 381.0
TH1_k127_5434008_2 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 310.0
TH1_k127_5434008_3 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002301 256.0
TH1_k127_5434008_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000004841 124.0
TH1_k127_5434008_5 SMART Chromosomal replication initiator DnaA domain - - - 0.000000000000000000000027 101.0
TH1_k127_5434008_6 Nucleotide binding protein, PINc - - - 0.00000007376 56.0
TH1_k127_5434008_7 - - - - 0.0000001353 59.0
TH1_k127_5434008_8 Cro/C1-type HTH DNA-binding domain - - - 0.000002233 57.0
TH1_k127_5438269_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 560.0
TH1_k127_5438269_1 protein secretion K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 532.0
TH1_k127_5438269_2 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 436.0
TH1_k127_5438269_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000003364 111.0
TH1_k127_5438269_5 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000001299 99.0
TH1_k127_5475001_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 5.688e-252 796.0
TH1_k127_5475001_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 3.061e-232 734.0
TH1_k127_5475001_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000008786 151.0
TH1_k127_5475001_3 Glu-tRNAGln amidotransferase C subunit K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000002049 116.0
TH1_k127_5475001_4 Nucleotidyl transferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000001197 87.0
TH1_k127_5475730_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 498.0
TH1_k127_5475730_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 415.0
TH1_k127_5475730_2 shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000002052 143.0
TH1_k127_5523622_0 FAD linked oxidase K18930 - - 0.0 1210.0
TH1_k127_5523622_1 L-Lactate permease K00427,K03303 - - 7.68e-301 932.0
TH1_k127_5523622_2 electron transport protein ykgF-putative 4Fe-4S containing oxidoreductase K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 602.0
TH1_k127_5523622_3 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 561.0
TH1_k127_5523622_4 COG0247 Fe-S K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 329.0
TH1_k127_5523622_5 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.00000000000000000000000000000000000000000001272 166.0
TH1_k127_5523622_6 Pfam:DUF162 K00782 - - 0.0000000000000000000000000000000000000004283 155.0
TH1_k127_5523622_7 Transposase - - - 0.00000000000000000000000000004841 118.0
TH1_k127_5555954_0 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 396.0
TH1_k127_5555954_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 332.0
TH1_k127_5555954_2 TIGRFAM oligoendopeptidase, M3 family K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000002176 248.0
TH1_k127_5569382_0 AsmA-like C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 480.0
TH1_k127_5569382_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 284.0
TH1_k127_5569382_2 addiction module antidote protein HigA K21498 - - 0.000000000000000000000000000000000000001136 149.0
TH1_k127_5569382_3 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000000000000004355 141.0
TH1_k127_5596924_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 316.0
TH1_k127_5596924_1 membrane transporter protein K07090 - - 0.00000000000000000000000001676 114.0
TH1_k127_5596924_2 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.00000000000000000000806 95.0
TH1_k127_5596924_3 PFAM Bacterial regulatory protein, arsR family - - - 0.00005303 47.0
TH1_k127_5635171_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.452e-239 748.0
TH1_k127_5635171_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000004017 190.0
TH1_k127_5635171_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000003873 143.0
TH1_k127_5635171_3 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000001086 88.0
TH1_k127_5759176_0 sensor diguanylate cyclase phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 485.0
TH1_k127_5759176_1 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 384.0
TH1_k127_5759176_2 Response regulator, receiver K11443 - - 0.000000000000000000000000000000000000000000005169 166.0
TH1_k127_5759176_3 Helix-hairpin-helix motif - - - 0.000000000000000000000000000000000000000005059 161.0
TH1_k127_5759176_4 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000003189 142.0
TH1_k127_5759176_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000004039 109.0
TH1_k127_5760431_0 Aminotransferase class-III K01845 - 5.4.3.8 4.799e-199 627.0
TH1_k127_5760431_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000003812 209.0
TH1_k127_5760431_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000003918 126.0
TH1_k127_5760431_3 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000867 70.0
TH1_k127_5760431_4 denitrification pathway K15876 - - 0.000579 49.0
TH1_k127_5846726_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 611.0
TH1_k127_5846726_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 574.0
TH1_k127_5846726_10 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000001059 231.0
TH1_k127_5846726_11 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000002352 220.0
TH1_k127_5846726_12 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000002043 196.0
TH1_k127_5846726_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000002878 177.0
TH1_k127_5846726_14 Crossover junction endodeoxyribonuclease RuvC K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000008808 141.0
TH1_k127_5846726_16 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.0000000000000000000006886 101.0
TH1_k127_5846726_17 Protein of unknown function (DUF2905) - - - 0.0000000000000001869 81.0
TH1_k127_5846726_18 Protein of unknown function DUF58 - - - 0.00000001864 59.0
TH1_k127_5846726_19 Sporulation related domain - - - 0.0000013 58.0
TH1_k127_5846726_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 475.0
TH1_k127_5846726_3 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 482.0
TH1_k127_5846726_4 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 423.0
TH1_k127_5846726_5 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 338.0
TH1_k127_5846726_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 338.0
TH1_k127_5846726_7 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003786 285.0
TH1_k127_5846726_8 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000001107 264.0
TH1_k127_5846726_9 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000002173 258.0
TH1_k127_5862402_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 2.188e-271 860.0
TH1_k127_5862402_1 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 300.0
TH1_k127_5862402_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000006336 143.0
TH1_k127_5862402_3 - - - - 0.0000000000000002646 80.0
TH1_k127_5903196_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 434.0
TH1_k127_5903196_1 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 299.0
TH1_k127_5903196_2 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 294.0
TH1_k127_5903196_3 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002388 292.0
TH1_k127_5903196_4 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000000000000000000000002538 136.0
TH1_k127_5903196_5 - - - - 0.000000000000000000001436 100.0
TH1_k127_5903196_6 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.000000000001038 81.0
TH1_k127_5909442_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 466.0
TH1_k127_5909442_1 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000001935 177.0
TH1_k127_5909442_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000004844 109.0
TH1_k127_605906_0 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 489.0
TH1_k127_605906_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001296 276.0
TH1_k127_605906_2 ABC1 family K03688 - - 0.00000000000000000000000000357 121.0
TH1_k127_6139317_0 Glycosyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 471.0
TH1_k127_6139317_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 378.0
TH1_k127_6139317_2 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000547 138.0
TH1_k127_6202205_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 513.0
TH1_k127_6202205_1 Smr domain - - - 0.00000000000000000000000000000006648 127.0
TH1_k127_6202205_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000001401 93.0
TH1_k127_6218647_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 381.0
TH1_k127_6218647_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006695 276.0
TH1_k127_6218647_2 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003442 218.0
TH1_k127_6218647_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000003147 167.0
TH1_k127_6218647_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000003262 150.0
TH1_k127_6218647_5 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000258 131.0
TH1_k127_6218647_6 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001328 106.0
TH1_k127_6218647_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000008823 74.0
TH1_k127_6222787_0 TRCF K03723 - - 2.238e-235 764.0
TH1_k127_6222787_1 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 571.0
TH1_k127_6222787_10 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 352.0
TH1_k127_6222787_11 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004269 277.0
TH1_k127_6222787_12 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006163 287.0
TH1_k127_6222787_13 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002952 271.0
TH1_k127_6222787_14 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000559 238.0
TH1_k127_6222787_15 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000003082 224.0
TH1_k127_6222787_16 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.000000000000000000000000000000000000000000000000000000000309 220.0
TH1_k127_6222787_17 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000003436 217.0
TH1_k127_6222787_18 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000007046 201.0
TH1_k127_6222787_19 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000154 183.0
TH1_k127_6222787_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 559.0
TH1_k127_6222787_20 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000002833 176.0
TH1_k127_6222787_21 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000007516 163.0
TH1_k127_6222787_22 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000000006295 149.0
TH1_k127_6222787_23 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000001723 138.0
TH1_k127_6222787_24 cell redox homeostasis - - - 0.0000000000000000000000000000000004705 144.0
TH1_k127_6222787_25 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000009059 136.0
TH1_k127_6222787_26 response to heat K06149,K07090 - - 0.000000000000000000000000000000008515 144.0
TH1_k127_6222787_27 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000004234 124.0
TH1_k127_6222787_28 Cell surface protein - - - 0.00000000000000002995 96.0
TH1_k127_6222787_29 - - - - 0.000000000004475 73.0
TH1_k127_6222787_3 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 495.0
TH1_k127_6222787_30 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.00000001187 58.0
TH1_k127_6222787_4 PAS domain K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 462.0
TH1_k127_6222787_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 434.0
TH1_k127_6222787_6 Chromate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 433.0
TH1_k127_6222787_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 422.0
TH1_k127_6222787_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 368.0
TH1_k127_6222787_9 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 362.0
TH1_k127_6227041_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 7.273e-319 990.0
TH1_k127_6227041_1 FAD binding domain K00394 - 1.8.99.2 9.338e-284 880.0
TH1_k127_6227041_2 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 1.199e-208 651.0
TH1_k127_6227041_3 FAD dependent oxidoreductase K16885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 606.0
TH1_k127_6227041_4 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000008017 244.0
TH1_k127_6227041_5 FAD binding domain K00394 - 1.8.99.2 0.00000000000000000000000000000000004969 134.0
TH1_k127_6243952_0 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 470.0
TH1_k127_6243952_1 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 314.0
TH1_k127_6243952_2 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000009437 125.0
TH1_k127_6247866_0 Protein export membrane protein K07003 - - 0.000000000000000001266 94.0
TH1_k127_6247866_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000368 93.0
TH1_k127_6247866_2 3-demethylubiquinone-9 3-O-methyltransferase activity K07003 - - 0.0000000000002304 81.0
TH1_k127_6247866_3 Protein export membrane protein K07003 - - 0.0003012 51.0
TH1_k127_6282740_0 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 421.0
TH1_k127_6282740_1 elongation factor Tu domain 2 protein K06207 - - 0.000000000000008782 74.0
TH1_k127_6287296_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 460.0
TH1_k127_6287296_1 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.000000000000000000000000000000000000000000000000000000000009825 215.0
TH1_k127_6287296_2 Protein of unknown function (DUF3187) - - - 0.00000000000000000000000006773 119.0
TH1_k127_6287296_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000001942 63.0
TH1_k127_6307428_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008449 252.0
TH1_k127_6307428_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000001055 250.0
TH1_k127_6307428_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002102 248.0
TH1_k127_6307428_3 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000007926 222.0
TH1_k127_6317663_0 L,D-transpeptidase catalytic domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 602.0
TH1_k127_6317663_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 440.0
TH1_k127_6317663_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 394.0
TH1_k127_6317663_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 319.0
TH1_k127_6317663_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 323.0
TH1_k127_6317663_5 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 308.0
TH1_k127_6317663_6 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004268 274.0
TH1_k127_6317663_7 viral genome integration into host DNA K04763 - - 0.000000000000000000000000004066 113.0
TH1_k127_6317663_8 Alanine-zipper, major outer membrane lipoprotein - - - 0.000000000000000337 83.0
TH1_k127_6317663_9 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000006353 50.0
TH1_k127_6319917_0 Large extracellular alpha-helical protein K06894 - - 0.0 1593.0
TH1_k127_6319917_1 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 528.0
TH1_k127_6319917_2 Glycosyltransferase family 28 N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 343.0
TH1_k127_6319917_3 ribonuclease BN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 289.0
TH1_k127_6319917_4 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000101 219.0
TH1_k127_6319917_5 O-methyltransferase family 3 - - - 0.0000000000000000000000000000000000000000000000000000000007348 210.0
TH1_k127_6319917_6 smart pdz dhr glgf - - - 0.0000000000000000000000000000000000000000000000009093 183.0
TH1_k127_6319917_7 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000003892 69.0
TH1_k127_6319917_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0003798 44.0
TH1_k127_6334235_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.601e-315 980.0
TH1_k127_6334235_1 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 1.336e-240 760.0
TH1_k127_6334235_10 Evidence 4 Homologs of previously reported genes of - - - 0.00000000004885 65.0
TH1_k127_6334235_2 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006578 561.0
TH1_k127_6334235_3 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 346.0
TH1_k127_6334235_4 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002026 261.0
TH1_k127_6334235_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000851 248.0
TH1_k127_6334235_6 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000004391 186.0
TH1_k127_6334235_7 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000001387 162.0
TH1_k127_6334235_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000003373 130.0
TH1_k127_6334235_9 Ubiquinol--cytochrome c reductase - - - 0.00000000000000000000000000001421 118.0
TH1_k127_6342908_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.101e-221 692.0
TH1_k127_6342908_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 481.0
TH1_k127_6342908_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 435.0
TH1_k127_6342908_3 - - - - 0.000000000000000000000000000000001244 134.0
TH1_k127_6342908_4 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000452 109.0
TH1_k127_6342908_5 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000007322 73.0
TH1_k127_6342908_6 nuclease activity - - - 0.000000001519 62.0
TH1_k127_6351522_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.541e-313 982.0
TH1_k127_6351522_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 498.0
TH1_k127_6351522_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 500.0
TH1_k127_6351522_3 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 469.0
TH1_k127_6351522_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000000001486 157.0
TH1_k127_6351522_5 phosphatidylglycerophosphatase activity K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.0000000000000000005004 89.0
TH1_k127_6351522_6 ATP synthase, subunit b - - - 0.0000003572 56.0
TH1_k127_6351522_7 RecX family K03565 - - 0.000122 50.0
TH1_k127_6403201_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 364.0
TH1_k127_6403201_1 Carbohydrate-binding family 9 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001762 283.0
TH1_k127_6403201_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000009078 253.0
TH1_k127_6403201_3 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000001786 235.0
TH1_k127_6403201_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000001919 211.0
TH1_k127_6403201_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000001509 187.0
TH1_k127_6403201_6 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.000000000000000000000000000000000000000000004121 166.0
TH1_k127_6403201_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000001015 131.0
TH1_k127_6403201_8 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000003783 130.0
TH1_k127_6403201_9 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000001849 81.0
TH1_k127_6404270_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 541.0
TH1_k127_6404270_1 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 466.0
TH1_k127_6404270_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000003953 219.0
TH1_k127_6404270_11 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000000000000000000001459 206.0
TH1_k127_6404270_12 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000007244 197.0
TH1_k127_6404270_13 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000008912 188.0
TH1_k127_6404270_14 NTPase - - - 0.0000000000000000000000000000000000003343 146.0
TH1_k127_6404270_15 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000005425 85.0
TH1_k127_6404270_16 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000000000000758 87.0
TH1_k127_6404270_17 formate dehydrogenase - - - 0.000000004662 65.0
TH1_k127_6404270_18 Acetyltransferase (GNAT) family - - - 0.000002726 56.0
TH1_k127_6404270_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 416.0
TH1_k127_6404270_3 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 387.0
TH1_k127_6404270_4 membrane K09133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 342.0
TH1_k127_6404270_5 Chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 317.0
TH1_k127_6404270_6 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 295.0
TH1_k127_6404270_7 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001309 276.0
TH1_k127_6404270_8 ATP cone domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004764 255.0
TH1_k127_6404270_9 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000001848 239.0
TH1_k127_6497842_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 2.393e-247 785.0
TH1_k127_6497842_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000002588 229.0
TH1_k127_6506951_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.212e-236 740.0
TH1_k127_6506951_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 5.852e-227 719.0
TH1_k127_6506951_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.238e-225 706.0
TH1_k127_6506951_3 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 316.0
TH1_k127_6506951_4 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000005903 192.0
TH1_k127_6524466_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 3.594e-226 720.0
TH1_k127_6524466_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 367.0
TH1_k127_6524466_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 297.0
TH1_k127_6524466_3 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000002096 206.0
TH1_k127_6524466_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000004973 132.0
TH1_k127_6524466_5 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000005371 88.0
TH1_k127_6524466_6 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.0000000000003333 74.0
TH1_k127_6528137_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 348.0
TH1_k127_6528137_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000231 277.0
TH1_k127_6528137_2 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009501 271.0
TH1_k127_6528137_3 Chemotaxis protein CheC K03410 - - 0.0000000000000000000000000000000000000000000000000000000009616 207.0
TH1_k127_6528137_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000002901 214.0
TH1_k127_6528137_5 COG0698 Ribose 5-phosphate isomerase RpiB - - - 0.0000000000000000000000000000000000000000000000000002106 190.0
TH1_k127_6528137_6 diguanylate cyclase - - - 0.000000000000000000000000000000000000000001236 178.0
TH1_k127_6528137_7 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.0000000000000000000002788 100.0
TH1_k127_6559855_0 40-residue yvtn family beta-propeller repeat protein - - - 1.293e-209 659.0
TH1_k127_6559855_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 340.0
TH1_k127_6559855_10 DUF167 - - - 0.0000000003111 64.0
TH1_k127_6559855_11 - - - - 0.00002835 50.0
TH1_k127_6559855_2 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 319.0
TH1_k127_6559855_3 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008479 283.0
TH1_k127_6559855_4 PFAM response regulator receiver K02483,K18344 - - 0.00000000000000000000000000000000000000000000000000000000000000000003755 239.0
TH1_k127_6559855_5 phosphatidate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000007031 235.0
TH1_k127_6559855_6 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000000000000000000002106 167.0
TH1_k127_6559855_7 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000005068 126.0
TH1_k127_6559855_8 RNA-binding protein containing a PIN domain K06962 - - 0.0000000000000000000000000464 112.0
TH1_k127_6559855_9 - - - - 0.0000000002999 63.0
TH1_k127_6661264_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 471.0
TH1_k127_6661264_1 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000007105 224.0
TH1_k127_6661264_2 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000000000000000000000009513 201.0
TH1_k127_6661264_3 MlaD protein K02067 - - 0.0000000000000000000000000003151 115.0
TH1_k127_6702278_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 401.0
TH1_k127_6702278_1 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000001605 188.0
TH1_k127_6786794_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 295.0
TH1_k127_6786794_1 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002701 266.0
TH1_k127_6786794_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004001 258.0
TH1_k127_6786794_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002844 232.0
TH1_k127_6786794_4 COG0463 Glycosyltransferases involved in cell wall biogenesis K13002 - - 0.00000000000000000000000000000000000000000000000000000000001349 215.0
TH1_k127_6786794_5 Glycosyl transferases group 1 K12989 - - 0.00000000000000000000000000009892 130.0
TH1_k127_6786794_6 Glycosyl transferase family 2 - - - 0.0000000001558 63.0
TH1_k127_6790042_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.742e-207 652.0
TH1_k127_6790042_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 352.0
TH1_k127_6790042_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000007689 154.0
TH1_k127_6790042_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000001206 130.0
TH1_k127_6790042_12 Ribosomal protein L36 K02919 - - 0.00000000000001949 72.0
TH1_k127_6790042_13 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000004198 72.0
TH1_k127_6790042_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000001163 68.0
TH1_k127_6790042_15 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0001568 48.0
TH1_k127_6790042_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 315.0
TH1_k127_6790042_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004407 276.0
TH1_k127_6790042_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000004012 231.0
TH1_k127_6790042_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000004742 212.0
TH1_k127_6790042_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000002528 201.0
TH1_k127_6790042_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001482 183.0
TH1_k127_6790042_8 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000007517 181.0
TH1_k127_6790042_9 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000297 159.0
TH1_k127_6790278_0 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 442.0
TH1_k127_6790278_1 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005259 270.0
TH1_k127_6790278_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000003662 221.0
TH1_k127_6790278_3 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000007518 169.0
TH1_k127_6794323_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 566.0
TH1_k127_6833079_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 406.0
TH1_k127_6833079_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000827 209.0
TH1_k127_6833079_2 Glycosyl transferase family 2 K09931 - - 0.00000000000000000000000000000000000000000000000000000005489 204.0
TH1_k127_6833079_3 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000002178 147.0
TH1_k127_6833079_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000001165 139.0
TH1_k127_6833079_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000001689 93.0
TH1_k127_6833079_6 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000002124 61.0
TH1_k127_6842752_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1223.0
TH1_k127_6842752_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 484.0
TH1_k127_6842752_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 390.0
TH1_k127_6842752_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000359 172.0
TH1_k127_6842752_4 LysM domain - - - 0.00000000000000000000000000000000000003793 156.0
TH1_k127_6842752_5 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000009459 137.0
TH1_k127_6842752_6 AMP binding - - - 0.000000000000000000001774 105.0
TH1_k127_6842752_7 Unextendable partial coding region - - - 0.0000000000000000001297 89.0
TH1_k127_6842752_8 DNA alkylation repair enzyme - - - 0.0000000000000939 73.0
TH1_k127_6936219_0 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 8.169e-305 952.0
TH1_k127_6936219_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 326.0
TH1_k127_6936219_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006178 259.0
TH1_k127_6936219_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000001273 220.0
TH1_k127_6936219_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000002431 190.0
TH1_k127_6936219_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000462 146.0
TH1_k127_6936219_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000002057 73.0
TH1_k127_6936219_7 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000006027 73.0
TH1_k127_6983519_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.908e-239 750.0
TH1_k127_6983519_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 431.0
TH1_k127_6983519_10 SpoVT / AbrB like domain - - - 0.0000000000000004801 84.0
TH1_k127_6983519_2 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 369.0
TH1_k127_6983519_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 364.0
TH1_k127_6983519_4 Restriction endonuclease K07448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 319.0
TH1_k127_6983519_5 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002052 275.0
TH1_k127_6983519_6 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000007205 182.0
TH1_k127_6983519_7 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.00000000000000000000000000000000000000000009113 166.0
TH1_k127_6983519_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000002259 160.0
TH1_k127_6983519_9 PIN domain - - - 0.00000000000000000000000000000000000001143 148.0
TH1_k127_7161521_0 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 399.0
TH1_k127_7161521_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 325.0
TH1_k127_7161521_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001801 276.0
TH1_k127_7161521_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000003323 186.0
TH1_k127_7161521_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000001181 117.0
TH1_k127_7171409_0 NOG31153 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004917 280.0
TH1_k127_7171409_1 DNA-binding transcription factor activity K03892 - - 0.00000000000004463 76.0
TH1_k127_7171409_2 Thioredoxin-like - - - 0.00000000000332 70.0
TH1_k127_7171409_3 - - - - 0.00000002264 59.0
TH1_k127_7189999_0 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000005985 200.0
TH1_k127_7189999_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000004325 130.0
TH1_k127_7189999_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000001098 105.0
TH1_k127_723228_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 3.271e-208 668.0
TH1_k127_723228_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 395.0
TH1_k127_723228_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 329.0
TH1_k127_723228_3 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001522 267.0
TH1_k127_723228_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000001573 194.0
TH1_k127_723228_5 Sh3 type 3 domain protein - - - 0.000000000000000000000000000000000000004729 150.0
TH1_k127_723228_6 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.00000000000000000000000005489 107.0
TH1_k127_723228_7 - - - - 0.00000000000003112 78.0
TH1_k127_723228_8 Aconitase C-terminal domain K01681 - 4.2.1.3 0.000000007043 57.0
TH1_k127_723228_9 Aconitase C-terminal domain K01681 - 4.2.1.3 0.000002465 49.0
TH1_k127_7331773_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 537.0
TH1_k127_7331773_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 448.0
TH1_k127_7331773_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000001725 98.0
TH1_k127_7407741_0 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000001033 241.0
TH1_k127_7407741_1 heat shock protein binding - - - 0.00000000000000000000000000000000000001131 155.0
TH1_k127_7407741_2 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000005361 140.0
TH1_k127_7407741_4 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000007459 69.0
TH1_k127_7407741_5 Belongs to the 'phage' integrase family - - - 0.00000003507 56.0
TH1_k127_7476295_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000002934 231.0
TH1_k127_7476295_1 Domain of Unknown Function (DUF350) K08989 - - 0.0000000000000000000000000000000005403 136.0
TH1_k127_7476295_2 thiolester hydrolase activity - - - 0.000000000000000000000002778 106.0
TH1_k127_7476295_3 Glutathionylspermidine synthase preATP-grasp - - - 0.00000000000000000000003748 101.0
TH1_k127_7540420_0 Putative peptidoglycan binding domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 487.0
TH1_k127_7540420_1 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 459.0
TH1_k127_7540420_2 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 346.0
TH1_k127_7540420_3 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000001516 261.0
TH1_k127_7540420_6 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.00000007109 57.0
TH1_k127_7628317_0 ABC transporter K15738 - - 5.981e-228 722.0
TH1_k127_7628317_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 597.0
TH1_k127_7628317_2 UDP-N-acetylmuramyl pentapeptide K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 332.0
TH1_k127_7628317_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.00000000000000000000000000000000000000000000000000009949 196.0
TH1_k127_7628317_4 bifunctional purine biosynthesis protein purh K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000003714 162.0
TH1_k127_7628317_5 COG1109 Phosphomannomutase K01840 GO:0003674,GO:0003824,GO:0004615,GO:0005975,GO:0008150,GO:0008152,GO:0016853,GO:0016866,GO:0016868,GO:0044238,GO:0071704 5.4.2.8 0.000000000000000000000000000002724 121.0
TH1_k127_7660792_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 532.0
TH1_k127_7660792_1 PFAM plasmid stabilization system - - - 0.00000000000000000000000005126 110.0
TH1_k127_7660792_2 Spore photoproduct lyase K03716 GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0016829,GO:0016830,GO:0043167,GO:0043169,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0070283,GO:0140097 4.1.99.14 0.000000000000000000000007813 112.0
TH1_k127_7660792_3 Putative addiction module component - - - 0.000000000000000001421 87.0
TH1_k127_7685651_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.297e-284 883.0
TH1_k127_7685651_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 487.0
TH1_k127_7685651_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 350.0
TH1_k127_7685651_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 317.0
TH1_k127_7685651_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 309.0
TH1_k127_7685651_5 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.000000000000000000000000000000000000000001676 162.0
TH1_k127_7685651_6 Short-chain dehydrogenase reductase Sdr - - - 0.00000000000000000000000000000004652 125.0
TH1_k127_7685651_7 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.000000000000000004278 96.0
TH1_k127_7685651_8 Sporulation and spore germination - - - 0.000000000002296 74.0
TH1_k127_7713300_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 8.994e-296 930.0
TH1_k127_7713300_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 596.0
TH1_k127_7713300_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 455.0
TH1_k127_7713300_3 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 342.0
TH1_k127_7713300_4 NAD(P)H dehydrogenase K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000007136 227.0
TH1_k127_7713300_5 PFAM Rhodanese domain protein - - - 0.000000000000000000000000000000007444 134.0
TH1_k127_7713300_6 thiosulfate sulfurtransferase activity - - - 0.00000000003635 64.0
TH1_k127_7848215_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 369.0
TH1_k127_7848215_1 - - - - 0.00000000000000000000000000000000000000000000000000000001553 207.0
TH1_k127_7848215_2 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000003147 139.0
TH1_k127_7848215_3 thiolester hydrolase activity - - - 0.00000000000000000000000000003905 121.0
TH1_k127_7848215_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000001234 110.0
TH1_k127_7848215_5 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000006507 74.0
TH1_k127_7848215_6 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000002956 71.0
TH1_k127_7848215_7 Acetyltransferase (GNAT) family K03824 - - 0.0000879 45.0
TH1_k127_7893571_0 Large extracellular alpha-helical protein K06894 - - 1.446e-249 785.0
TH1_k127_7893571_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 2.358e-225 720.0
TH1_k127_7893571_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 556.0
TH1_k127_7893571_3 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 304.0
TH1_k127_7893571_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000002281 183.0
TH1_k127_7893571_5 - - - - 0.00000000000000000000002888 105.0
TH1_k127_7893571_6 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000003302 82.0
TH1_k127_8024401_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1146.0
TH1_k127_8024401_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 401.0
TH1_k127_8024401_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 363.0
TH1_k127_8024401_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000003331 237.0
TH1_k127_8024401_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000003248 216.0
TH1_k127_8024401_5 protein conserved in bacteria K09928 - - 0.000000000000001101 82.0
TH1_k127_8024401_6 sulfur carrier activity K04085 - - 0.0000000000007236 71.0
TH1_k127_8081209_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 1.168e-216 677.0
TH1_k127_8081209_1 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 515.0
TH1_k127_8081209_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 413.0
TH1_k127_8081209_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 299.0
TH1_k127_8081209_4 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 290.0
TH1_k127_8081209_5 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 285.0
TH1_k127_8081209_6 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000006942 254.0
TH1_k127_8081209_7 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000004352 167.0
TH1_k127_8081209_8 ThiS family K03636 - - 0.000000000000000000000000000000001029 132.0
TH1_k127_8081209_9 NIL - - - 0.000000000000000000000000002066 112.0
TH1_k127_8217312_0 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 351.0
TH1_k127_8217312_1 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 307.0
TH1_k127_8217312_2 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000808 162.0
TH1_k127_8217312_3 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000006265 65.0
TH1_k127_8217312_4 PFAM ABC transporter K09013 - - 0.0000000001412 63.0
TH1_k127_8217312_5 PFAM Uncharacterised protein family UPF0150 - - - 0.0000102 49.0
TH1_k127_8217312_6 DNA modification - - - 0.0005401 43.0
TH1_k127_8244290_0 PFAM Integrase, catalytic region - - - 1.302e-198 632.0
TH1_k127_8244290_1 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 302.0
TH1_k127_8249055_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 7.122e-279 869.0
TH1_k127_8249055_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 538.0
TH1_k127_8249055_10 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000007695 132.0
TH1_k127_8249055_11 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.000000000000000000001082 103.0
TH1_k127_8249055_12 Two component signalling adaptor domain K03408 - - 0.00000000000000000004659 98.0
TH1_k127_8249055_13 phosphate K02040 - - 0.0000004094 57.0
TH1_k127_8249055_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 536.0
TH1_k127_8249055_3 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 400.0
TH1_k127_8249055_4 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 290.0
TH1_k127_8249055_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004351 305.0
TH1_k127_8249055_6 Pyridoxal-phosphate dependent enzyme K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000003141 247.0
TH1_k127_8249055_7 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000000000000005084 172.0
TH1_k127_8249055_8 Ferric uptake regulator family K09825 - - 0.000000000000000000000000000000000000001128 152.0
TH1_k127_8249055_9 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000000000001004 147.0
TH1_k127_8278577_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 1.294e-237 758.0
TH1_k127_8278577_1 Iron-sulfur cluster-binding domain K06871 - - 3.47e-217 680.0
TH1_k127_8278577_10 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001469 285.0
TH1_k127_8278577_11 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001395 261.0
TH1_k127_8278577_12 PFAM Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000004944 248.0
TH1_k127_8278577_13 nucleotide catabolic process - - - 0.000000000000000000000000000000000000000000000000006378 186.0
TH1_k127_8278577_14 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000001542 177.0
TH1_k127_8278577_15 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000002433 179.0
TH1_k127_8278577_16 Glutathione peroxidase - - - 0.00000000000000000000000000000000001461 142.0
TH1_k127_8278577_17 - - - - 0.000000001255 62.0
TH1_k127_8278577_18 Protein of unknown function (DUF433) - - - 0.00000005122 56.0
TH1_k127_8278577_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 544.0
TH1_k127_8278577_20 Psort location Cytoplasmic, score K03655 - 3.6.4.12 0.0009065 44.0
TH1_k127_8278577_3 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 407.0
TH1_k127_8278577_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 419.0
TH1_k127_8278577_5 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 376.0
TH1_k127_8278577_6 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 356.0
TH1_k127_8278577_7 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 334.0
TH1_k127_8278577_8 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 325.0
TH1_k127_8278577_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 322.0
TH1_k127_8314686_0 Chemotaxis phosphatase CheX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 306.0
TH1_k127_8314686_1 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000004873 183.0
TH1_k127_8314686_2 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.00000000000000000000000000000008003 142.0
TH1_k127_8314686_3 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000001764 94.0
TH1_k127_8314686_4 Phospholipid methyltransferase - - - 0.00000000000000004889 95.0
TH1_k127_8393895_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 3.076e-204 649.0
TH1_k127_8393895_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 503.0
TH1_k127_8393895_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 363.0
TH1_k127_8393895_3 CO dehydrogenase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 292.0
TH1_k127_8393895_4 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000001014 204.0
TH1_k127_8393895_5 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000004146 139.0
TH1_k127_84193_0 Sigma-54 interaction domain K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 407.0
TH1_k127_84193_1 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 302.0
TH1_k127_84193_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 301.0
TH1_k127_84193_3 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002294 259.0
TH1_k127_84193_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000631 256.0
TH1_k127_84193_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000001484 224.0
TH1_k127_84193_6 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000001235 218.0
TH1_k127_84193_7 Rubrerythrin - - - 0.00000000000000000000000000000000009124 134.0
TH1_k127_8476256_0 Domain of unknown function (DUF4139) - - - 3.918e-203 642.0
TH1_k127_8476256_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000005704 208.0
TH1_k127_8476256_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000004759 190.0
TH1_k127_8476256_3 Putative zinc-finger - - - 0.0000000000000008625 89.0
TH1_k127_8476256_4 Cytochrome c K08738 - - 0.000000005303 58.0
TH1_k127_8476256_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000002891 61.0
TH1_k127_8477762_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.326e-202 638.0
TH1_k127_8477762_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 483.0
TH1_k127_8477762_10 helicase activity - - - 0.000006537 52.0
TH1_k127_8477762_2 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 341.0
TH1_k127_8477762_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000003937 261.0
TH1_k127_8477762_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000005513 232.0
TH1_k127_8477762_5 - - - - 0.000000000000000000000000000000000000000000000000001081 187.0
TH1_k127_8477762_6 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.000000000000000000000000000000000000000000000009614 181.0
TH1_k127_8477762_7 Protein of unknown function (DUF1189) - - - 0.00000000000000000000000000000000002703 145.0
TH1_k127_8477762_8 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000002461 117.0
TH1_k127_8477762_9 - - - - 0.000000000000000009299 84.0
TH1_k127_8492467_0 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000004388 188.0
TH1_k127_8492467_1 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000001834 163.0
TH1_k127_8492467_2 - - - - 0.0000000002232 65.0
TH1_k127_8505700_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 462.0
TH1_k127_8505700_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 374.0
TH1_k127_8505700_10 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000002181 55.0
TH1_k127_8505700_11 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00004046 47.0
TH1_k127_8505700_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 348.0
TH1_k127_8505700_3 SPTR Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000001222 167.0
TH1_k127_8505700_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000005045 143.0
TH1_k127_8505700_5 nuclease activity K06218 - - 0.0000000000000000000003952 98.0
TH1_k127_8505700_6 cheY-homologous receiver domain - - - 0.000000000000000002988 90.0
TH1_k127_8505700_7 Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000007646 88.0
TH1_k127_8505700_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000001267 79.0
TH1_k127_8505700_9 TraY domain K18918 - - 0.00000003902 57.0
TH1_k127_8536132_0 Di-haem cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 493.0
TH1_k127_8536132_1 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000002546 187.0
TH1_k127_8536132_2 radical SAM domain protein - - - 0.000000000000000000000000000001804 133.0
TH1_k127_857708_0 ABC transporter K06158 - - 7.216e-232 732.0
TH1_k127_857708_1 Rhodanese Homology Domain - - - 0.0000000000001773 73.0
TH1_k127_8599832_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 538.0
TH1_k127_8599832_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 522.0
TH1_k127_8599832_10 Domain of unknown function (DUF1858) - - - 0.00000000000000003866 83.0
TH1_k127_8599832_11 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000005566 67.0
TH1_k127_8599832_12 Sulfurtransferase TusA - - - 0.00000000001306 68.0
TH1_k127_8599832_13 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000008907 55.0
TH1_k127_8599832_14 4Fe-4S binding domain - - - 0.00000377 49.0
TH1_k127_8599832_2 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 325.0
TH1_k127_8599832_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 312.0
TH1_k127_8599832_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000009985 259.0
TH1_k127_8599832_5 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000001231 219.0
TH1_k127_8599832_6 - - - - 0.00000000000000000000000000000000000000000000000000000000007285 211.0
TH1_k127_8599832_7 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000001332 194.0
TH1_k127_8599832_8 nucleotidyltransferase activity K07075 - - 0.000000000000000000000000003464 123.0
TH1_k127_8599832_9 Protein of unknown function (DUF3617) - - - 0.00000000000000000000003533 105.0
TH1_k127_8678521_0 cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007189 250.0
TH1_k127_8678521_1 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000671 241.0
TH1_k127_8687060_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 2.042e-214 673.0
TH1_k127_8687060_1 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 413.0
TH1_k127_8687060_10 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000004053 118.0
TH1_k127_8687060_11 Domain of unknown function (DUF370) K09777 - - 0.000000000000000000000000003896 113.0
TH1_k127_8687060_12 Tetratricopeptide repeat - - - 0.00000000000000000001521 104.0
TH1_k127_8687060_13 Psort location Cytoplasmic, score - - - 0.00000000000000000195 86.0
TH1_k127_8687060_14 Roadblock/LC7 domain - - - 0.000000000000000003496 89.0
TH1_k127_8687060_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 386.0
TH1_k127_8687060_3 Creatinase Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004247 282.0
TH1_k127_8687060_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000001031 243.0
TH1_k127_8687060_5 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000004645 207.0
TH1_k127_8687060_6 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000004659 195.0
TH1_k127_8687060_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000001618 183.0
TH1_k127_8687060_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000003315 180.0
TH1_k127_8687060_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000003803 162.0
TH1_k127_8703442_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 5.838e-290 901.0
TH1_k127_8703442_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 378.0
TH1_k127_8703442_2 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000319 225.0
TH1_k127_8703442_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000003919 201.0
TH1_k127_8703442_4 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000001288 182.0
TH1_k127_8703442_5 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000145 165.0
TH1_k127_8703442_6 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000004708 109.0
TH1_k127_8736368_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 616.0
TH1_k127_8736368_1 citrate synthase K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 389.0
TH1_k127_8736368_2 - - - - 0.0000007855 53.0
TH1_k127_8736368_3 PFAM PilT protein domain protein - - - 0.000001723 55.0
TH1_k127_8764218_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 4.313e-200 641.0
TH1_k127_8764218_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 394.0
TH1_k127_8764218_11 integral membrane protein - - - 0.00000004624 58.0
TH1_k127_8764218_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 396.0
TH1_k127_8764218_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 350.0
TH1_k127_8764218_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000131 236.0
TH1_k127_8764218_5 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000000000000000000000000000000002758 198.0
TH1_k127_8764218_6 addiction module antidote protein HigA K21498 - - 0.000000000000000000000000001369 114.0
TH1_k127_8764218_7 - - - - 0.0000000000000000007101 92.0
TH1_k127_8764218_8 Tetratricopeptide repeat - - - 0.0000000002832 65.0
TH1_k127_8792641_0 cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000282 251.0
TH1_k127_8792641_1 lyase activity - - - 0.0000000000000000000000000001198 127.0
TH1_k127_8814247_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1105.0
TH1_k127_8814247_1 Ftsk_gamma K03466 - - 2.464e-197 637.0
TH1_k127_8814247_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 405.0
TH1_k127_8814247_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002282 283.0
TH1_k127_8814247_4 pyridoxamine 5-phosphate oxidase-related K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000002066 232.0
TH1_k127_8814247_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000001651 147.0
TH1_k127_8814247_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000375 136.0
TH1_k127_8814247_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00005748 53.0
TH1_k127_8814247_8 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.0003843 49.0
TH1_k127_8831646_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 552.0
TH1_k127_8835217_0 Phosphoglycerate kinase K00927 - 2.7.2.3 6.203e-197 620.0
TH1_k127_8835217_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 482.0
TH1_k127_8835217_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 354.0
TH1_k127_8835217_3 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 359.0
TH1_k127_8934499_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006136 256.0
TH1_k127_8934499_1 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000107 246.0
TH1_k127_8934499_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000005761 219.0
TH1_k127_8934499_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000008465 215.0
TH1_k127_8934499_4 FtsX-like permease family - - - 0.0000000000000000000000000000004474 128.0
TH1_k127_8934499_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000005115 109.0
TH1_k127_8934499_6 Thioredoxin-like - - - 0.0000000000000000004768 90.0
TH1_k127_8934499_7 ABC transporter substrate binding protein K01989 - - 0.00000000000002986 83.0
TH1_k127_8975576_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.684e-252 790.0
TH1_k127_8975576_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 597.0
TH1_k127_8975576_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 297.0
TH1_k127_8975576_3 DNA methylase K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000001103 231.0
TH1_k127_8975576_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000008876 117.0
TH1_k127_9068720_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 415.0
TH1_k127_9068720_1 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 354.0
TH1_k127_9068720_10 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.000000000000000000000000002862 119.0
TH1_k127_9068720_11 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000000003863 106.0
TH1_k127_9068720_12 signal-transduction protein containing cAMP-binding and CBS domains K07315 - 3.1.3.3 0.00000000000000001571 95.0
TH1_k127_9068720_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 325.0
TH1_k127_9068720_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 307.0
TH1_k127_9068720_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 302.0
TH1_k127_9068720_5 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008988 282.0
TH1_k127_9068720_6 Branched-chain amino acid ABC transporter, ATP-binding protein K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002156 277.0
TH1_k127_9068720_7 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000005585 247.0
TH1_k127_9068720_8 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001831 242.0
TH1_k127_9068720_9 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000001874 190.0
TH1_k127_9101615_0 phosphorelay signal transduction system K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 439.0
TH1_k127_9101615_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000001188 222.0
TH1_k127_9101615_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.0001075 47.0
TH1_k127_9130718_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 470.0
TH1_k127_9130718_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 446.0
TH1_k127_924285_0 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 390.0
TH1_k127_924285_1 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 317.0
TH1_k127_924285_2 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002659 279.0
TH1_k127_924285_3 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004155 259.0
TH1_k127_924285_4 cell redox homeostasis - - - 0.000000000000000000000000000007043 119.0
TH1_k127_924285_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000005155 78.0
TH1_k127_9271761_0 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 373.0
TH1_k127_9271761_1 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 360.0
TH1_k127_9271761_2 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000002288 174.0
TH1_k127_9354256_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 2.071e-259 819.0
TH1_k127_9354256_1 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 323.0
TH1_k127_9354256_2 PFAM cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 311.0
TH1_k127_9354256_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000006323 81.0
TH1_k127_9354256_4 - - - - 0.0000000000004662 70.0
TH1_k127_9358539_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 569.0
TH1_k127_9358539_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002383 273.0
TH1_k127_9358539_2 HD domain - - - 0.0000000000000000000000000000000000002161 143.0
TH1_k127_9359779_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 437.0
TH1_k127_9359779_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 322.0
TH1_k127_9359779_10 Stringent starvation protein B K09985 - - 0.000000000000000000000000000001389 125.0
TH1_k127_9359779_11 PFAM EamA-like transporter family - - - 0.00000000000000000000000000105 123.0
TH1_k127_9359779_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008965 270.0
TH1_k127_9359779_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000001312 241.0
TH1_k127_9359779_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000001429 232.0
TH1_k127_9359779_5 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000007909 221.0
TH1_k127_9359779_6 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000001468 196.0
TH1_k127_9359779_7 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000003805 202.0
TH1_k127_9359779_8 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000181 183.0
TH1_k127_9359779_9 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000006676 132.0
TH1_k127_9398773_0 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 618.0
TH1_k127_9398773_1 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 375.0
TH1_k127_9398773_2 TonB-dependent receptor, beta-barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004941 253.0
TH1_k127_9398773_3 Leucine-rich repeat (LRR) protein - - - 0.0000000000002262 76.0
TH1_k127_9464004_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 400.0
TH1_k127_9464004_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007793 292.0
TH1_k127_9464004_2 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000002297 124.0
TH1_k127_9464004_3 Diguanylate cyclase - - - 0.00000000000000000000000004565 124.0
TH1_k127_9464004_4 drug transmembrane transporter activity K03327,K18908 GO:0000302,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0006857,GO:0006862,GO:0006950,GO:0006979,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015215,GO:0015230,GO:0015238,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015893,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0033554,GO:0034220,GO:0034599,GO:0034614,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0042891,GO:0042895,GO:0042938,GO:0044464,GO:0044610,GO:0046677,GO:0050896,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1901700,GO:1901701,GO:1904680 - 0.00000000000000000003317 92.0
TH1_k127_955114_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 2.85e-216 679.0
TH1_k127_955114_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.529e-211 662.0
TH1_k127_955114_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 518.0
TH1_k127_955114_3 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002978 286.0
TH1_k127_955114_4 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000001488 250.0
TH1_k127_955114_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000002233 235.0
TH1_k127_955114_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000002809 195.0
TH1_k127_955114_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000001498 120.0
TH1_k127_955114_9 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000291 113.0
TH1_k127_9554465_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 7e-323 994.0
TH1_k127_9554465_1 all-trans-retinol 13,14-reductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 552.0
TH1_k127_9554465_2 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000001215 182.0
TH1_k127_9554465_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000001601 173.0
TH1_k127_9554465_4 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.000000000000000000000000000000000000000495 149.0
TH1_k127_9554465_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000006183 152.0
TH1_k127_9554465_6 - K07071 - - 0.000000000000000000000000008052 116.0
TH1_k127_9561136_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 7.074e-229 724.0
TH1_k127_9561136_1 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 4.484e-211 675.0
TH1_k127_9561136_2 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 349.0
TH1_k127_9561136_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.0000000000000000000000000000000000000000000000000005401 190.0
TH1_k127_9561136_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000007431 188.0
TH1_k127_9561136_5 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000001907 104.0
TH1_k127_9561136_6 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.00001269 55.0
TH1_k127_9612745_0 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000003874 139.0
TH1_k127_9612745_1 PAS fold - - - 0.0000000000000000000000000000000002085 147.0
TH1_k127_9612745_2 Protein of unknown function DUF86 - - - 0.00000000000000000001133 95.0
TH1_k127_9612745_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000945 99.0
TH1_k127_9612745_4 nucleotidyltransferase activity - - - 0.0000000000004695 74.0
TH1_k127_9612745_5 Response regulator receiver - - - 0.00000000006268 74.0
TH1_k127_995858_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 468.0
TH1_k127_995858_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 418.0
TH1_k127_995858_10 PFAM Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000008114 156.0
TH1_k127_995858_11 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000004856 137.0
TH1_k127_995858_12 iron-sulfur cluster assembly - - - 0.000000000000000000000133 98.0
TH1_k127_995858_13 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.00000005729 62.0
TH1_k127_995858_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 353.0
TH1_k127_995858_3 Family 5 K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 364.0
TH1_k127_995858_4 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 351.0
TH1_k127_995858_5 HlyD family K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 304.0
TH1_k127_995858_6 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 295.0
TH1_k127_995858_7 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000849 276.0
TH1_k127_995858_8 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000697 275.0
TH1_k127_995858_9 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000006593 239.0