Overview

ID MAG03894
Name TH2_bin.12
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class BSN033
Order BSN033
Family UBA1163
Genus UBA1163
Species
Assembly information
Completeness (%) 97.03
Contamination (%) 6.77
GC content (%) 46.0
N50 (bp) 23,318
Genome size (bp) 4,704,387

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4271

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1015099_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1090.0
TH2_k127_1015099_1 Asparagine synthase K01953 - 6.3.5.4 5.042e-197 630.0
TH2_k127_1015099_10 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000002094 170.0
TH2_k127_1015099_11 Protein of unknown function (DUF2905) - - - 0.0000000000000000004713 88.0
TH2_k127_1015099_2 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 619.0
TH2_k127_1015099_3 ABC-type multidrug transport system ATPase and permease K06147,K06148,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 578.0
TH2_k127_1015099_4 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 377.0
TH2_k127_1015099_5 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 372.0
TH2_k127_1015099_6 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000001403 210.0
TH2_k127_1015099_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000003155 212.0
TH2_k127_1015099_8 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000000000002214 214.0
TH2_k127_1015099_9 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000313 196.0
TH2_k127_102573_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 480.0
TH2_k127_102573_1 - - - - 0.00000000000000000000000000000000000000000000000000318 186.0
TH2_k127_102573_2 PFAM SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000006325 190.0
TH2_k127_102573_3 RNA recognition motif - - - 0.000000000000000000000000001006 115.0
TH2_k127_102573_4 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000003867 111.0
TH2_k127_102573_5 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000000871 111.0
TH2_k127_102573_6 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000265 93.0
TH2_k127_102573_7 PFAM glycoside hydrolase, family 13 domain protein - - - 0.000000000000000004181 87.0
TH2_k127_1100572_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1100.0
TH2_k127_1100572_1 AsmA-like C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 336.0
TH2_k127_1100572_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000257 224.0
TH2_k127_1100572_3 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000000000000005059 191.0
TH2_k127_1100572_4 diguanylate cyclase - - - 0.00000000000000002832 91.0
TH2_k127_1145654_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 436.0
TH2_k127_1145654_1 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 395.0
TH2_k127_1145654_2 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 323.0
TH2_k127_1145654_3 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001209 279.0
TH2_k127_1145654_4 helix_turn _helix lactose operon repressor K02525,K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002411 281.0
TH2_k127_1145654_5 Fumarate K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008668 270.0
TH2_k127_1145654_6 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000003176 237.0
TH2_k127_1145654_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000002553 141.0
TH2_k127_1145654_8 Conserved carboxylase domain K00627,K01571,K01960,K03416,K20140 - 2.1.3.1,2.3.1.12,4.1.1.3,6.4.1.1,6.4.1.7 0.000000101 54.0
TH2_k127_1171916_0 4Fe-4S dicluster domain - - - 1.619e-275 856.0
TH2_k127_1171916_1 4Fe-4S dicluster domain - - - 9.277e-247 771.0
TH2_k127_1171916_2 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 371.0
TH2_k127_1171916_3 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000000000000000001009 141.0
TH2_k127_1171916_4 - - - - 0.00008558 47.0
TH2_k127_1178750_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 2.693e-205 656.0
TH2_k127_1178750_1 Alpha amylase, catalytic domain K01176 - 3.2.1.1 9.33e-200 631.0
TH2_k127_1178750_10 PFAM short chain dehydrogenase K00046,K00065,K18009 - 1.1.1.127,1.1.1.304,1.1.1.69,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 295.0
TH2_k127_1178750_11 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003292 263.0
TH2_k127_1178750_12 arylformamidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003581 263.0
TH2_k127_1178750_13 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008709 273.0
TH2_k127_1178750_14 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000005238 252.0
TH2_k127_1178750_15 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005159 248.0
TH2_k127_1178750_16 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000001141 202.0
TH2_k127_1178750_17 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000006175 204.0
TH2_k127_1178750_18 Aldolase K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000002378 197.0
TH2_k127_1178750_19 PFAM Rubrerythrin K19824 - - 0.0000000000000000000000000000000000000000000000002427 179.0
TH2_k127_1178750_2 fatty acid transporter K02106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 614.0
TH2_k127_1178750_21 heme oxygenase (decyclizing) activity K21481 - 1.14.99.57 0.0000229 48.0
TH2_k127_1178750_3 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 612.0
TH2_k127_1178750_4 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 477.0
TH2_k127_1178750_5 alcohol dehydrogenase K19954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 397.0
TH2_k127_1178750_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 359.0
TH2_k127_1178750_7 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 352.0
TH2_k127_1178750_8 COG0006 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 317.0
TH2_k127_1178750_9 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 300.0
TH2_k127_1193873_0 FAD linked oxidase domain protein K00803,K11472 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 590.0
TH2_k127_1193873_1 FGGY family of carbohydrate kinases, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 561.0
TH2_k127_1193873_10 Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0) K22364 - 1.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 316.0
TH2_k127_1193873_11 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 301.0
TH2_k127_1193873_12 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000007658 272.0
TH2_k127_1193873_13 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000002868 259.0
TH2_k127_1193873_14 lactate metabolic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000009384 230.0
TH2_k127_1193873_15 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000009197 212.0
TH2_k127_1193873_16 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000005038 214.0
TH2_k127_1193873_17 Pfam:Kce K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000001238 209.0
TH2_k127_1193873_18 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000001387 209.0
TH2_k127_1193873_19 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000004442 197.0
TH2_k127_1193873_2 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 551.0
TH2_k127_1193873_20 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000007306 184.0
TH2_k127_1193873_21 - - - - 0.000000000000000000000000000000000000001035 152.0
TH2_k127_1193873_22 DeoR C terminal sensor domain - GO:0005975,GO:0006066,GO:0006071,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016052,GO:0019219,GO:0019222,GO:0019400,GO:0019405,GO:0019563,GO:0019751,GO:0031323,GO:0031326,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901575,GO:1901615,GO:1901616,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000006677 155.0
TH2_k127_1193873_23 Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family - - - 0.0000000000000000000000000003547 120.0
TH2_k127_1193873_24 4Fe-4S ferredoxin iron-sulfur binding domain K18979 - 1.17.99.6 0.0000000000000000000000000006581 122.0
TH2_k127_1193873_25 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 0.000000001609 68.0
TH2_k127_1193873_26 Cupin domain - - - 0.0000007004 55.0
TH2_k127_1193873_3 ABC transporter K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 425.0
TH2_k127_1193873_4 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 381.0
TH2_k127_1193873_5 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 353.0
TH2_k127_1193873_6 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 359.0
TH2_k127_1193873_7 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 329.0
TH2_k127_1193873_8 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 339.0
TH2_k127_1193873_9 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 323.0
TH2_k127_120177_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 1.116e-240 751.0
TH2_k127_120177_1 CoA-substrate-specific enzyme activase - - - 6.256e-211 694.0
TH2_k127_120177_11 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000002997 102.0
TH2_k127_120177_12 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000000003133 102.0
TH2_k127_120177_13 - - - - 0.00000000000000000000008456 101.0
TH2_k127_120177_14 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000000003152 99.0
TH2_k127_120177_15 Protein of unknown function (DUF2628) - - - 0.00000000005251 74.0
TH2_k127_120177_17 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.0000000002762 61.0
TH2_k127_120177_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 473.0
TH2_k127_120177_3 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 390.0
TH2_k127_120177_4 Bax inhibitor 1 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 314.0
TH2_k127_120177_5 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001444 249.0
TH2_k127_120177_6 peptidase activity, acting on L-amino acid peptides - - - 0.0000000000000000000000000000000000000000000000000000000000001067 228.0
TH2_k127_120177_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000002483 196.0
TH2_k127_120177_8 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000007649 190.0
TH2_k127_120177_9 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000005925 169.0
TH2_k127_1210775_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 475.0
TH2_k127_1210775_1 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 413.0
TH2_k127_1210775_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001627 265.0
TH2_k127_1210775_3 PFAM glycoside hydrolase, family 13 domain protein - - - 0.000000000000000000007077 95.0
TH2_k127_1210775_4 PFAM Class III cytochrome C family - - - 0.0000000000000001942 83.0
TH2_k127_1240318_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 413.0
TH2_k127_1240318_1 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 293.0
TH2_k127_1240318_2 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000009089 236.0
TH2_k127_1240318_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000003157 130.0
TH2_k127_1240318_4 PFAM nitroreductase - - - 0.000000005482 62.0
TH2_k127_1292141_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1493.0
TH2_k127_1292141_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 376.0
TH2_k127_1292141_2 Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 359.0
TH2_k127_1292141_3 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 295.0
TH2_k127_1292141_4 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000000000009669 119.0
TH2_k127_1292141_5 - - - - 0.000000000000008367 82.0
TH2_k127_1292681_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 5.066e-273 853.0
TH2_k127_1292681_1 SCP-2 sterol transfer family - - - 1.466e-252 796.0
TH2_k127_1292681_10 PFAM Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 356.0
TH2_k127_1292681_11 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 355.0
TH2_k127_1292681_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 349.0
TH2_k127_1292681_13 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 312.0
TH2_k127_1292681_14 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 302.0
TH2_k127_1292681_15 PFAM Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001945 275.0
TH2_k127_1292681_16 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000001237 216.0
TH2_k127_1292681_17 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000001054 216.0
TH2_k127_1292681_18 PFAM DoxX K15977 - - 0.000000000000000000000000000001035 126.0
TH2_k127_1292681_19 sequence-specific DNA binding - - - 0.0000000000000000000004183 97.0
TH2_k127_1292681_2 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 3.825e-232 732.0
TH2_k127_1292681_20 response to heat - - - 0.0000000000000005187 82.0
TH2_k127_1292681_21 4Fe-4S single cluster domain of Ferredoxin I - - - 0.000000000000004191 76.0
TH2_k127_1292681_22 sequence-specific DNA binding K18830 - - 0.000000000000006837 76.0
TH2_k127_1292681_23 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.000000000001081 79.0
TH2_k127_1292681_24 PFAM YcfA-like protein - - - 0.0000001956 54.0
TH2_k127_1292681_25 - - - - 0.000000276 54.0
TH2_k127_1292681_3 Belongs to the glycosyl hydrolase 57 family - - - 5.26e-205 666.0
TH2_k127_1292681_4 Fumarase C C-terminus K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 559.0
TH2_k127_1292681_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 520.0
TH2_k127_1292681_6 PFAM AAA ATPase central domain protein K06027 - 3.6.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 485.0
TH2_k127_1292681_7 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 460.0
TH2_k127_1292681_8 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 415.0
TH2_k127_1292681_9 conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 394.0
TH2_k127_132657_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1115.0
TH2_k127_132657_1 HlyD family secretion protein K15727 - - 1.049e-224 703.0
TH2_k127_132657_10 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000004633 137.0
TH2_k127_132657_11 HEPN domain K09132 - - 0.00000000000000000000000000000003915 131.0
TH2_k127_132657_12 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000003858 119.0
TH2_k127_132657_13 Nucleotidyltransferase domain - - - 0.00000000002549 68.0
TH2_k127_132657_14 K+ potassium transporter K03549 - - 0.0000000003237 61.0
TH2_k127_132657_15 Feruloyl esterase K21105 - 3.1.1.102 0.0000000103 60.0
TH2_k127_132657_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 501.0
TH2_k127_132657_3 PFAM 4Fe-4S K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 408.0
TH2_k127_132657_4 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 336.0
TH2_k127_132657_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000001391 246.0
TH2_k127_132657_6 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000001151 205.0
TH2_k127_132657_7 Belongs to the ComB family K05979 - 3.1.3.71 0.000000000000000000000000000000000000000000000000001577 191.0
TH2_k127_132657_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000006227 167.0
TH2_k127_1355784_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 366.0
TH2_k127_1355784_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 353.0
TH2_k127_1355784_10 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000001267 208.0
TH2_k127_1355784_11 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000005036 192.0
TH2_k127_1355784_12 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000001396 187.0
TH2_k127_1355784_13 Thioesterase superfamily K02614 - - 0.000000000000000000000000000000000000000000000003273 177.0
TH2_k127_1355784_14 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000001202 144.0
TH2_k127_1355784_15 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000001093 128.0
TH2_k127_1355784_16 ACT domain protein - - - 0.000000000000000000000000003708 117.0
TH2_k127_1355784_17 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000035 105.0
TH2_k127_1355784_18 translation release factor activity - - - 0.00000000000000000002686 94.0
TH2_k127_1355784_19 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' - - - 0.000000000000002082 85.0
TH2_k127_1355784_2 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 332.0
TH2_k127_1355784_20 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000001276 76.0
TH2_k127_1355784_21 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - 0.000000000001025 69.0
TH2_k127_1355784_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 318.0
TH2_k127_1355784_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 310.0
TH2_k127_1355784_5 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001642 280.0
TH2_k127_1355784_6 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006634 274.0
TH2_k127_1355784_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001183 266.0
TH2_k127_1355784_8 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007626 257.0
TH2_k127_1355784_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002207 249.0
TH2_k127_1358274_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 5.7e-322 998.0
TH2_k127_1358274_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.227e-287 908.0
TH2_k127_1358274_10 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 439.0
TH2_k127_1358274_11 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 439.0
TH2_k127_1358274_12 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 413.0
TH2_k127_1358274_13 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 370.0
TH2_k127_1358274_14 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 359.0
TH2_k127_1358274_15 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 349.0
TH2_k127_1358274_16 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 335.0
TH2_k127_1358274_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 307.0
TH2_k127_1358274_18 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000003397 263.0
TH2_k127_1358274_19 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000001209 236.0
TH2_k127_1358274_2 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 K03738 - 1.2.7.5 2.936e-224 708.0
TH2_k127_1358274_20 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000002825 231.0
TH2_k127_1358274_21 PFAM Uncharacterised BCR, COG1649 K11931 - - 0.00000000000000000000000000000000000000000000000000000000000000001444 243.0
TH2_k127_1358274_22 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000171 241.0
TH2_k127_1358274_23 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002823 226.0
TH2_k127_1358274_24 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000000000000003944 212.0
TH2_k127_1358274_25 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000002016 210.0
TH2_k127_1358274_26 S-acyltransferase activity K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000002099 201.0
TH2_k127_1358274_27 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000005016 186.0
TH2_k127_1358274_28 dTDP-4-dehydrorhamnose 3,5-epimerase activity - - - 0.0000000000000000000000000000000000000000000000002216 179.0
TH2_k127_1358274_29 response regulator receiver - - - 0.0000000000000000000000000000000000000000000007699 186.0
TH2_k127_1358274_3 Molybdate transporter of MFS superfamily - - - 8.675e-200 626.0
TH2_k127_1358274_30 - - - - 0.0000000000000000000000000000000000000001486 161.0
TH2_k127_1358274_31 Transcriptional regulator, LysR family K02019 - - 0.00000000000000000000000982 104.0
TH2_k127_1358274_33 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000002741 76.0
TH2_k127_1358274_34 Tetratricopeptide repeat - - - 0.000000000005812 76.0
TH2_k127_1358274_35 Endonuclease/Exonuclease/phosphatase family - - - 0.00000001255 66.0
TH2_k127_1358274_37 - - - - 0.0000002574 57.0
TH2_k127_1358274_38 Transposase, Mutator family - - - 0.00007463 45.0
TH2_k127_1358274_39 Domain of unknown function (DUF4124) - - - 0.0001137 51.0
TH2_k127_1358274_4 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 619.0
TH2_k127_1358274_40 Pfam:DUF1049 - - - 0.0001219 48.0
TH2_k127_1358274_41 PEP-CTERM motif - - - 0.0001873 51.0
TH2_k127_1358274_5 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 543.0
TH2_k127_1358274_6 SMART Elongator protein 3 MiaB NifB K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 502.0
TH2_k127_1358274_7 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 472.0
TH2_k127_1358274_8 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 475.0
TH2_k127_1358274_9 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 483.0
TH2_k127_1367000_0 SWIM zinc finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 448.0
TH2_k127_1367000_1 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000001778 143.0
TH2_k127_1367000_2 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000005571 124.0
TH2_k127_1367000_3 DNA-binding transcription factor activity K02444,K03655 - 3.6.4.12 0.0001351 46.0
TH2_k127_1376649_0 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000000000000007963 183.0
TH2_k127_1376649_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000001402 177.0
TH2_k127_1376649_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000549 89.0
TH2_k127_1376649_4 Transposase K07483 - - 0.0000000000001255 72.0
TH2_k127_138008_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000001013 259.0
TH2_k127_138008_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002122 256.0
TH2_k127_138008_2 alpha,alpha-trehalase activity K03931 GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000000000000000000000000000000000000000000000000000000004733 238.0
TH2_k127_138008_3 - - - - 0.000000000000000000000000000000000000000000000000000007825 191.0
TH2_k127_138008_4 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000002525 169.0
TH2_k127_138008_5 HNH nucleases - - - 0.0000000000000000000000000000000000000000371 154.0
TH2_k127_138008_6 - - - - 0.000000000000000000000411 99.0
TH2_k127_138008_7 DNA-sulfur modification-associated - - - 0.0000000000000000003778 100.0
TH2_k127_138008_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000001705 88.0
TH2_k127_1389272_0 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 574.0
TH2_k127_1389272_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004505 276.0
TH2_k127_1389272_2 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000004144 245.0
TH2_k127_1389272_3 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000005934 224.0
TH2_k127_1389272_4 Calcineurin-like phosphoesterase superfamily domain K03269 - 3.6.1.54 0.00000000000000000000000000000000007975 143.0
TH2_k127_1389272_5 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000001039 98.0
TH2_k127_1389272_6 - - - - 0.000000003205 60.0
TH2_k127_1420099_0 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 428.0
TH2_k127_1420099_1 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 319.0
TH2_k127_1420099_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 306.0
TH2_k127_1420099_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000002135 214.0
TH2_k127_1420099_4 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000001345 195.0
TH2_k127_1442422_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 354.0
TH2_k127_1442422_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 295.0
TH2_k127_1442422_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000003881 134.0
TH2_k127_1461594_0 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000001031 223.0
TH2_k127_1461594_1 Protein of unknown function (DUF4239) - - - 0.000000000000000000000000000000000000000000000000000000000000002046 226.0
TH2_k127_1461594_2 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000001355 216.0
TH2_k127_1461594_3 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000006392 201.0
TH2_k127_1461594_4 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000373 175.0
TH2_k127_1461594_5 FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000144 126.0
TH2_k127_1461594_6 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000001507 136.0
TH2_k127_1461594_7 - - - - 0.00000000000000000000000001106 109.0
TH2_k127_1461594_8 Cupin domain - - - 0.000000000008325 70.0
TH2_k127_1461594_9 Sigma-54 interaction domain K10126 - - 0.0000001331 55.0
TH2_k127_1480679_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 7.901e-253 795.0
TH2_k127_1480679_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 7.971e-237 745.0
TH2_k127_1480679_10 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 448.0
TH2_k127_1480679_11 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856 434.0
TH2_k127_1480679_12 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 420.0
TH2_k127_1480679_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 414.0
TH2_k127_1480679_14 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 392.0
TH2_k127_1480679_15 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 394.0
TH2_k127_1480679_16 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 382.0
TH2_k127_1480679_17 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 374.0
TH2_k127_1480679_18 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 376.0
TH2_k127_1480679_19 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 363.0
TH2_k127_1480679_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 5.921e-197 620.0
TH2_k127_1480679_20 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 359.0
TH2_k127_1480679_21 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 350.0
TH2_k127_1480679_22 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 339.0
TH2_k127_1480679_23 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 308.0
TH2_k127_1480679_24 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 307.0
TH2_k127_1480679_25 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 298.0
TH2_k127_1480679_26 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 297.0
TH2_k127_1480679_27 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001371 251.0
TH2_k127_1480679_28 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000004705 234.0
TH2_k127_1480679_29 Stationary phase survival protein, YicC family, YicC_N and DUF1732 domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000002101 231.0
TH2_k127_1480679_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 3.888e-195 614.0
TH2_k127_1480679_30 peptidyl-tyrosine sulfation K03217,K06872 - - 0.00000000000000000000000000000000000000000000000000000000000003664 230.0
TH2_k127_1480679_31 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000003825 217.0
TH2_k127_1480679_32 ATPase associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000002422 226.0
TH2_k127_1480679_33 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000001828 213.0
TH2_k127_1480679_34 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000004191 210.0
TH2_k127_1480679_35 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000000004216 201.0
TH2_k127_1480679_36 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000000000000000004347 198.0
TH2_k127_1480679_37 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000003788 189.0
TH2_k127_1480679_38 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000001138 185.0
TH2_k127_1480679_39 - - - - 0.00000000000000000000000000000000000000000003387 169.0
TH2_k127_1480679_4 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 611.0
TH2_k127_1480679_40 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000002029 154.0
TH2_k127_1480679_41 NusB family K03625 - - 0.0000000000000000000000000000000000005578 144.0
TH2_k127_1480679_42 PFAM thioesterase superfamily K02614 - - 0.000000000000000000000000000000000005233 141.0
TH2_k127_1480679_43 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000005567 136.0
TH2_k127_1480679_44 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000003686 128.0
TH2_k127_1480679_45 YacP-like NYN domain K06962 - - 0.0000000000000000000000000006682 120.0
TH2_k127_1480679_46 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.000000000000000000000000001307 114.0
TH2_k127_1480679_47 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000002168 112.0
TH2_k127_1480679_48 - - - - 0.0000000000000000000003369 101.0
TH2_k127_1480679_49 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000004312 93.0
TH2_k127_1480679_5 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 574.0
TH2_k127_1480679_50 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000001955 86.0
TH2_k127_1480679_51 oxidoreductase activity - - - 0.00000000000000009762 94.0
TH2_k127_1480679_52 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000003879 78.0
TH2_k127_1480679_53 FCD - - - 0.0000000007718 63.0
TH2_k127_1480679_55 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000005419 57.0
TH2_k127_1480679_57 SnoaL-like polyketide cyclase - - - 0.00000006963 55.0
TH2_k127_1480679_6 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 489.0
TH2_k127_1480679_60 Cytosol aminopeptidase family, N-terminal domain - - - 0.000001059 58.0
TH2_k127_1480679_61 formylmethanofuran dehydrogenase subunit C K00202 - 1.2.7.12 0.000002802 58.0
TH2_k127_1480679_62 membrane - - - 0.000009839 48.0
TH2_k127_1480679_7 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 475.0
TH2_k127_1480679_8 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 467.0
TH2_k127_1480679_9 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 458.0
TH2_k127_1487251_0 Conserved carboxylase domain K01960 - 6.4.1.1 2.075e-218 687.0
TH2_k127_1487251_1 X-Pro dipeptidyl-peptidase domain protein K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 471.0
TH2_k127_1490323_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 591.0
TH2_k127_1490323_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 471.0
TH2_k127_1490323_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 461.0
TH2_k127_1490323_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 449.0
TH2_k127_1490323_4 carboxypeptidase activity K12941,K13048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 445.0
TH2_k127_1490323_5 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 344.0
TH2_k127_1490323_6 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 304.0
TH2_k127_1490323_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000001314 148.0
TH2_k127_1490323_8 ParB-like nuclease domain - - - 0.00000000000000000000000000000007057 132.0
TH2_k127_1496842_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 587.0
TH2_k127_1496842_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 579.0
TH2_k127_1496842_10 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002887 276.0
TH2_k127_1496842_11 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002219 271.0
TH2_k127_1496842_12 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000000000008462 153.0
TH2_k127_1496842_13 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000007573 149.0
TH2_k127_1496842_14 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000001573 126.0
TH2_k127_1496842_15 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000003459 121.0
TH2_k127_1496842_17 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000005813 108.0
TH2_k127_1496842_18 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000008838 103.0
TH2_k127_1496842_19 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000004435 63.0
TH2_k127_1496842_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 481.0
TH2_k127_1496842_20 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.00000006263 54.0
TH2_k127_1496842_3 Transketolase, pyrimidine binding domain K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 418.0
TH2_k127_1496842_4 Dehydrogenase E1 component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 398.0
TH2_k127_1496842_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 370.0
TH2_k127_1496842_6 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 364.0
TH2_k127_1496842_7 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 299.0
TH2_k127_1496842_8 amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 293.0
TH2_k127_1496842_9 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007631 285.0
TH2_k127_1505681_0 PFAM Transposase IS66 family K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 548.0
TH2_k127_1505681_1 - - - - 0.00006409 51.0
TH2_k127_152546_0 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 381.0
TH2_k127_152546_1 nitrite reductase (NAD(P)H) large subunit K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000001654 175.0
TH2_k127_152546_2 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000001462 168.0
TH2_k127_1531790_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 1.125e-265 844.0
TH2_k127_1531790_1 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 517.0
TH2_k127_1531790_10 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008051 279.0
TH2_k127_1531790_11 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004275 271.0
TH2_k127_1531790_12 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006228 270.0
TH2_k127_1531790_13 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003187 252.0
TH2_k127_1531790_14 NAD(P)-binding Rossmann-like domain K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000000000000000008124 250.0
TH2_k127_1531790_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002056 243.0
TH2_k127_1531790_16 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000007982 234.0
TH2_k127_1531790_17 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.000000000000000000000000000000000000000000000000001351 190.0
TH2_k127_1531790_18 sAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000000000000003161 183.0
TH2_k127_1531790_19 Predicted permease K07089 - - 0.0000000000000000000000000000000000001329 149.0
TH2_k127_1531790_2 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 404.0
TH2_k127_1531790_20 NMT1-like family K07080 - - 0.000000000000000000000000000000000001205 152.0
TH2_k127_1531790_21 NMT1-like family K07080 - - 0.000000000000000000000000000000000007244 150.0
TH2_k127_1531790_22 NMT1-like family K07080 - - 0.0000000000000000000000000000000002758 145.0
TH2_k127_1531790_23 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000004617 130.0
TH2_k127_1531790_24 DMSO reductase anchor subunit (DmsC) - - - 0.00000000000000000000000001117 121.0
TH2_k127_1531790_25 CoA binding domain K01905,K22224 - 6.2.1.13 0.0000000000000000721 82.0
TH2_k127_1531790_27 Domain of unknown function (DUF4388) - - - 0.0000004534 62.0
TH2_k127_1531790_28 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0002839 44.0
TH2_k127_1531790_3 AMP-binding enzyme C-terminal domain K02363,K04116 - 2.7.7.58,6.3.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 389.0
TH2_k127_1531790_4 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 372.0
TH2_k127_1531790_5 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 351.0
TH2_k127_1531790_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 352.0
TH2_k127_1531790_7 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 337.0
TH2_k127_1531790_8 base-excision repair K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 322.0
TH2_k127_1531790_9 4Fe-4S dicluster domain K08358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 289.0
TH2_k127_1535104_0 BFD-like [2Fe-2S] binding domain K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 507.0
TH2_k127_1535104_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00112 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000603 246.0
TH2_k127_1535104_2 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.00000000000000000000000000000000000000000000002524 177.0
TH2_k127_1535114_0 AMP-binding enzyme K01897 - 6.2.1.3 4.719e-212 676.0
TH2_k127_1535114_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 612.0
TH2_k127_1535114_10 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 388.0
TH2_k127_1535114_11 PFAM ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 378.0
TH2_k127_1535114_12 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 360.0
TH2_k127_1535114_13 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 359.0
TH2_k127_1535114_14 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 346.0
TH2_k127_1535114_15 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004284 284.0
TH2_k127_1535114_16 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003727 272.0
TH2_k127_1535114_17 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003187 254.0
TH2_k127_1535114_18 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000295 248.0
TH2_k127_1535114_19 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002411 246.0
TH2_k127_1535114_2 Aminotransferase K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 532.0
TH2_k127_1535114_20 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000001278 242.0
TH2_k127_1535114_21 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000000000000000000000000000000000000004797 248.0
TH2_k127_1535114_22 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000004236 230.0
TH2_k127_1535114_23 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000007276 199.0
TH2_k127_1535114_24 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000006733 196.0
TH2_k127_1535114_25 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000002362 177.0
TH2_k127_1535114_26 PFAM Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000000000000000005639 173.0
TH2_k127_1535114_27 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000204 157.0
TH2_k127_1535114_28 MaoC like domain - - - 0.000000000000000000000000000000000000001094 154.0
TH2_k127_1535114_29 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000001996 151.0
TH2_k127_1535114_3 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 509.0
TH2_k127_1535114_30 binding domain protein - - - 0.00000000000000000000000000000000003142 145.0
TH2_k127_1535114_31 Thiamine-binding protein - - - 0.000000000000000000000000000001094 123.0
TH2_k127_1535114_32 RNA recognition motif - - - 0.00000000000000000000000000173 114.0
TH2_k127_1535114_33 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000001231 100.0
TH2_k127_1535114_34 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.00000000000000009118 91.0
TH2_k127_1535114_35 - - - - 0.0000007985 54.0
TH2_k127_1535114_36 Probable zinc-ribbon domain - - - 0.000307 45.0
TH2_k127_1535114_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 511.0
TH2_k127_1535114_5 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 496.0
TH2_k127_1535114_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 488.0
TH2_k127_1535114_7 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 492.0
TH2_k127_1535114_8 PFAM acyl-CoA dehydrogenase domain protein K00249,K11731 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 444.0
TH2_k127_1535114_9 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 412.0
TH2_k127_1544801_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.679e-283 885.0
TH2_k127_1544801_1 FAD binding domain K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 3.377e-243 762.0
TH2_k127_1544801_10 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000005422 208.0
TH2_k127_1544801_11 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000008017 201.0
TH2_k127_1544801_12 Iron-containing alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000002734 213.0
TH2_k127_1544801_13 curli production assembly transport component CsgG - - - 0.00000000000000000000000000000000000000000005533 175.0
TH2_k127_1544801_14 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000006139 151.0
TH2_k127_1544801_15 - - - - 0.00000000000003894 85.0
TH2_k127_1544801_16 helix_turn_helix isocitrate lyase regulation - - - 0.0000000711 58.0
TH2_k127_1544801_17 TRAP transporter, 4TM 12TM fusion protein - - - 0.00000343 53.0
TH2_k127_1544801_18 Molybdopterin converting factor, small subunit K03636 - - 0.0000151 51.0
TH2_k127_1544801_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.192e-216 696.0
TH2_k127_1544801_3 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 508.0
TH2_k127_1544801_4 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 411.0
TH2_k127_1544801_5 AMP-binding enzyme C-terminal domain K02363 - 2.7.7.58,6.3.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 411.0
TH2_k127_1544801_6 protein involved in propionate catabolism K01720 - 4.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 401.0
TH2_k127_1544801_7 protein deglycase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 284.0
TH2_k127_1544801_8 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001542 299.0
TH2_k127_1544801_9 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000368 226.0
TH2_k127_1556575_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 496.0
TH2_k127_1556575_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 387.0
TH2_k127_1556575_2 Thiamine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 353.0
TH2_k127_1556575_3 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 349.0
TH2_k127_1556575_4 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 309.0
TH2_k127_1556575_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000004699 164.0
TH2_k127_1556575_6 Predicted membrane protein (DUF2318) K09005 - - 0.0000000000000000000000000000000000000008114 156.0
TH2_k127_1556575_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000008799 93.0
TH2_k127_156582_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 3.94e-310 965.0
TH2_k127_156582_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 4.563e-284 902.0
TH2_k127_156582_10 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 309.0
TH2_k127_156582_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 313.0
TH2_k127_156582_12 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000664 278.0
TH2_k127_156582_13 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000615 228.0
TH2_k127_156582_14 GntR family - - - 0.00000000000000000000000000000000000000000000000000000000006812 211.0
TH2_k127_156582_15 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000003633 184.0
TH2_k127_156582_16 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000007683 196.0
TH2_k127_156582_17 Protein of unknown function (DUF434) - - - 0.000000000000000000000000000000000000000000000001058 184.0
TH2_k127_156582_18 Protease prsW family - - - 0.0000000000000000000000000000000000000000000002472 179.0
TH2_k127_156582_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 5.028e-258 804.0
TH2_k127_156582_20 Glutaredoxin K03676,K04771 - 3.4.21.107 0.000000000001409 69.0
TH2_k127_156582_21 MlaC protein K07323 - - 0.00000000006247 71.0
TH2_k127_156582_23 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.00001502 48.0
TH2_k127_156582_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 6.771e-252 788.0
TH2_k127_156582_4 PFAM Enoyl-CoA hydratase isomerase - - - 1.076e-212 679.0
TH2_k127_156582_5 Reverse transcriptase K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 610.0
TH2_k127_156582_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 484.0
TH2_k127_156582_7 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009804 475.0
TH2_k127_156582_8 PFAM AMP-dependent synthetase and ligase K00666,K01897,K12508 - 6.2.1.3,6.2.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007977 452.0
TH2_k127_156582_9 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 431.0
TH2_k127_1612520_0 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002052 252.0
TH2_k127_1612520_1 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000001157 137.0
TH2_k127_1627116_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 520.0
TH2_k127_1627116_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 447.0
TH2_k127_1627116_10 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000007471 228.0
TH2_k127_1627116_12 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000004816 194.0
TH2_k127_1627116_13 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0000000000000000000000000000000000000000000000000005669 184.0
TH2_k127_1627116_14 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000002215 180.0
TH2_k127_1627116_15 - - - - 0.0000000000000000000000000000000000000000009675 160.0
TH2_k127_1627116_16 OmpA family K03640 - - 0.00000000000000000000000000000000000005902 150.0
TH2_k127_1627116_17 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.0000000000000000000000000000000000305 138.0
TH2_k127_1627116_18 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000028 140.0
TH2_k127_1627116_19 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000000000000000000000006973 130.0
TH2_k127_1627116_2 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 438.0
TH2_k127_1627116_20 Na -dependent transporter K03453 - - 0.0000000000000000000000006964 115.0
TH2_k127_1627116_21 Catalase K03781 - 1.11.1.6 0.0000000000000000000001995 97.0
TH2_k127_1627116_22 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000001563 91.0
TH2_k127_1627116_23 NHL repeat - - - 0.0000000000000000002183 102.0
TH2_k127_1627116_24 superoxide reductase activity K05919 - 1.15.1.2 0.0000000000000000002808 92.0
TH2_k127_1627116_25 SpoVT / AbrB like domain - - - 0.0000000000000000006171 87.0
TH2_k127_1627116_26 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000002071 81.0
TH2_k127_1627116_27 - - - - 0.000000002025 60.0
TH2_k127_1627116_29 PFAM NLP P60 protein K11060,K21471 - - 0.0000002489 60.0
TH2_k127_1627116_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 391.0
TH2_k127_1627116_31 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000007146 49.0
TH2_k127_1627116_32 Domain of unknown function (DUF4124) - - - 0.0003327 53.0
TH2_k127_1627116_33 Protein of unknown function (DUF1326) - - - 0.0003927 49.0
TH2_k127_1627116_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 376.0
TH2_k127_1627116_5 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 367.0
TH2_k127_1627116_6 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 346.0
TH2_k127_1627116_7 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005933 269.0
TH2_k127_1627116_8 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005269 252.0
TH2_k127_1627116_9 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000001414 229.0
TH2_k127_1666228_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 4.669e-286 886.0
TH2_k127_1666228_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 486.0
TH2_k127_1666228_10 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003169 252.0
TH2_k127_1666228_11 - - - - 0.00000000000000000000000000000000000000000000000000000009327 205.0
TH2_k127_1666228_12 Bacterial protein of unknown function (YtfJ_HI0045) K07109 - - 0.00000000000000000000000000000000000000000000000003216 184.0
TH2_k127_1666228_13 Histidine kinase - - - 0.00000000000000000000000000000000000009423 163.0
TH2_k127_1666228_14 - - - - 0.0000000000000001447 85.0
TH2_k127_1666228_15 PucR C-terminal helix-turn-helix domain - - - 0.0000000000007128 82.0
TH2_k127_1666228_16 Las17-binding protein actin regulator - - - 0.00000003408 57.0
TH2_k127_1666228_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 409.0
TH2_k127_1666228_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 345.0
TH2_k127_1666228_4 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 316.0
TH2_k127_1666228_5 alpha/beta hydrolase fold K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 315.0
TH2_k127_1666228_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 299.0
TH2_k127_1666228_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001885 275.0
TH2_k127_1666228_8 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001553 270.0
TH2_k127_1666228_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000001179 264.0
TH2_k127_1685422_0 NADH flavin oxidoreductase NADH oxidase K00354 - 1.6.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 380.0
TH2_k127_1685422_1 PFAM iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 304.0
TH2_k127_1685422_2 SCP-2 sterol transfer family - - - 0.0000000000000000000000006194 109.0
TH2_k127_1685422_3 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 K03738 - 1.2.7.5 0.00000000000000000006758 93.0
TH2_k127_1685422_4 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000009455 93.0
TH2_k127_1685422_5 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000002042 84.0
TH2_k127_1685422_7 - - - - 0.00008974 52.0
TH2_k127_1743204_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 4.426e-204 646.0
TH2_k127_1743204_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009068 283.0
TH2_k127_1743204_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000001723 111.0
TH2_k127_1779104_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 462.0
TH2_k127_1779104_1 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 462.0
TH2_k127_1779104_10 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000004781 151.0
TH2_k127_1779104_11 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000689 112.0
TH2_k127_1779104_12 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000006048 103.0
TH2_k127_1779104_13 PFAM Fimbrial assembly K02663 - - 0.0000000000000005548 85.0
TH2_k127_1779104_14 regulatory protein, FmdB family - - - 0.000000000001815 71.0
TH2_k127_1779104_15 Tetratricopeptide repeat - - - 0.00000000003576 76.0
TH2_k127_1779104_16 Ornithine decarboxylase inhibitor-putative sigma54 transciptional regulator K02584 - - 0.0002263 45.0
TH2_k127_1779104_2 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 428.0
TH2_k127_1779104_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 387.0
TH2_k127_1779104_4 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 371.0
TH2_k127_1779104_5 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 390.0
TH2_k127_1779104_6 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 364.0
TH2_k127_1779104_7 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000000000008479 213.0
TH2_k127_1779104_8 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000000000000000000000000000000000000000000003424 179.0
TH2_k127_1779104_9 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000008075 162.0
TH2_k127_1826759_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 351.0
TH2_k127_1826759_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000216 181.0
TH2_k127_1826759_3 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000008673 172.0
TH2_k127_183648_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1212.0
TH2_k127_183648_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 8.077e-227 711.0
TH2_k127_183648_10 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 392.0
TH2_k127_183648_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 384.0
TH2_k127_183648_12 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 368.0
TH2_k127_183648_13 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 342.0
TH2_k127_183648_14 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 340.0
TH2_k127_183648_15 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 322.0
TH2_k127_183648_16 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000178 269.0
TH2_k127_183648_17 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003464 254.0
TH2_k127_183648_18 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000482 223.0
TH2_k127_183648_19 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000009391 173.0
TH2_k127_183648_2 General secretory system II, protein E domain protein K02652 - - 7.161e-215 683.0
TH2_k127_183648_20 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000001105 131.0
TH2_k127_183648_21 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000001482 68.0
TH2_k127_183648_22 TPR Domain containing protein K12600 - - 0.00006571 56.0
TH2_k127_183648_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 9.956e-212 670.0
TH2_k127_183648_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 578.0
TH2_k127_183648_5 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 530.0
TH2_k127_183648_6 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 516.0
TH2_k127_183648_7 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 468.0
TH2_k127_183648_8 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 449.0
TH2_k127_183648_9 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 406.0
TH2_k127_1853962_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 564.0
TH2_k127_1853962_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 502.0
TH2_k127_1853962_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 320.0
TH2_k127_1853962_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000006352 140.0
TH2_k127_1853962_4 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.000000000000001012 79.0
TH2_k127_1853962_5 Branched-chain amino acid transport system / permease component K01998 - - 0.000000002643 63.0
TH2_k127_1853962_6 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.00004319 48.0
TH2_k127_1889622_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1305.0
TH2_k127_1889622_1 B-1 B cell differentiation - - - 0.0 1071.0
TH2_k127_1889622_10 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 419.0
TH2_k127_1889622_11 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 414.0
TH2_k127_1889622_12 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 402.0
TH2_k127_1889622_13 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 391.0
TH2_k127_1889622_14 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 378.0
TH2_k127_1889622_15 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 364.0
TH2_k127_1889622_16 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 341.0
TH2_k127_1889622_17 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 338.0
TH2_k127_1889622_18 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000001279 258.0
TH2_k127_1889622_19 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000000000000000000002176 222.0
TH2_k127_1889622_2 Aldehyde dehydrogenase family K22187 - - 9.79e-202 639.0
TH2_k127_1889622_20 PIN domain - - - 0.0000000000000000000000000000000000000000000000000001784 188.0
TH2_k127_1889622_21 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000006162 183.0
TH2_k127_1889622_22 Serine aminopeptidase, S33 K06889,K07397 - - 0.000000000000000000000000000000000000000000000001021 183.0
TH2_k127_1889622_23 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000001594 165.0
TH2_k127_1889622_24 PFAM membrane-bound metal-dependent hydrolase K07038 - - 0.0000000000000000000000000000000000000000001817 171.0
TH2_k127_1889622_25 Essential cell division protein K03589 - - 0.000000000000000000000000000000000000007143 156.0
TH2_k127_1889622_26 positive regulation of growth - - - 0.0000000000000000000000000000000000001534 143.0
TH2_k127_1889622_27 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.000000000000000000000000000000000138 133.0
TH2_k127_1889622_28 Curli production assembly/transport component CsgG - - - 0.000000000000000349 90.0
TH2_k127_1889622_3 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 3.126e-196 621.0
TH2_k127_1889622_31 NAD+ diphosphatase activity K01515,K03426 - 3.6.1.13,3.6.1.22 0.00000000007738 74.0
TH2_k127_1889622_32 - - - - 0.0000005735 60.0
TH2_k127_1889622_33 Stage II sporulation D domain protein K06381 - - 0.000003458 59.0
TH2_k127_1889622_34 lipoprotein YddW precursor - - - 0.00001273 54.0
TH2_k127_1889622_35 Helix-turn-helix domain - - - 0.0003777 48.0
TH2_k127_1889622_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.861e-194 614.0
TH2_k127_1889622_5 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 607.0
TH2_k127_1889622_6 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 539.0
TH2_k127_1889622_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 466.0
TH2_k127_1889622_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 444.0
TH2_k127_1889622_9 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 447.0
TH2_k127_1908161_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.396e-301 942.0
TH2_k127_1908161_1 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 1.033e-268 851.0
TH2_k127_1908161_10 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 397.0
TH2_k127_1908161_11 TRAP transporter solute receptor TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 372.0
TH2_k127_1908161_12 DnaJ molecular chaperone homology domain K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 351.0
TH2_k127_1908161_13 PFAM fumarate reductase succinate dehydrogenase flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 328.0
TH2_k127_1908161_14 Carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 302.0
TH2_k127_1908161_15 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 286.0
TH2_k127_1908161_16 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 287.0
TH2_k127_1908161_17 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001079 289.0
TH2_k127_1908161_18 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000001317 256.0
TH2_k127_1908161_19 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000006737 262.0
TH2_k127_1908161_2 Domain of unknown function (DUF3394) - - - 3.352e-253 796.0
TH2_k127_1908161_20 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000112 211.0
TH2_k127_1908161_21 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000003151 205.0
TH2_k127_1908161_22 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000004011 192.0
TH2_k127_1908161_23 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000003676 193.0
TH2_k127_1908161_24 lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000001389 191.0
TH2_k127_1908161_25 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.0000000000000000000000000000000000000000002167 164.0
TH2_k127_1908161_26 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000007217 169.0
TH2_k127_1908161_27 RNA methyltransferase K09761 - 2.1.1.193 0.0000000000000000000000000000000000000001393 161.0
TH2_k127_1908161_28 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00798 - 2.5.1.17 0.00000000000000000000000000000000000003334 149.0
TH2_k127_1908161_29 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000002022 130.0
TH2_k127_1908161_3 MMPL family K07003 - - 6.719e-237 768.0
TH2_k127_1908161_30 Rubrerythrin - - - 0.0000000000000000105 89.0
TH2_k127_1908161_31 Phosphopantetheine attachment site K02078 - - 0.00000000000000003702 84.0
TH2_k127_1908161_32 - - - - 0.00000000000000006384 83.0
TH2_k127_1908161_33 - - - - 0.0000000000001015 76.0
TH2_k127_1908161_34 Sulphur transport K07112 - - 0.0000000000007599 68.0
TH2_k127_1908161_35 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000421 60.0
TH2_k127_1908161_36 Protein of unknown function (DUF3108) - - - 0.000000009748 66.0
TH2_k127_1908161_37 B12 binding domain - - - 0.00000004378 56.0
TH2_k127_1908161_38 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000015 58.0
TH2_k127_1908161_4 Belongs to the ClpX chaperone family - - - 1.549e-210 672.0
TH2_k127_1908161_5 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 543.0
TH2_k127_1908161_6 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 526.0
TH2_k127_1908161_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 521.0
TH2_k127_1908161_8 carboxylic ester hydrolase activity K15357 - 3.5.1.106 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 504.0
TH2_k127_1908161_9 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008474 456.0
TH2_k127_1981673_0 Tripartite tricarboxylate transporter TctA family K07793 - - 2.251e-196 626.0
TH2_k127_1981673_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 617.0
TH2_k127_1981673_10 L-phenylalanine transmembrane transporter activity K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001849 278.0
TH2_k127_1981673_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003311 266.0
TH2_k127_1981673_12 Glycerophosphoryl diester phosphodiesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007104 259.0
TH2_k127_1981673_13 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000012 241.0
TH2_k127_1981673_14 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000006087 233.0
TH2_k127_1981673_15 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000008486 231.0
TH2_k127_1981673_16 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000002487 233.0
TH2_k127_1981673_17 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519,K16878 - 1.2.5.3,1.3.99.8 0.00000000000000000000000000000000000000000000000000000000000008115 223.0
TH2_k127_1981673_18 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000007391 205.0
TH2_k127_1981673_19 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000004942 211.0
TH2_k127_1981673_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01464,K01465 - 3.5.2.2,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 569.0
TH2_k127_1981673_20 Domain of unknown function (DUF4392) - - - 0.00000000000000000000000000000000000000000000000000000000891 211.0
TH2_k127_1981673_21 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000056 199.0
TH2_k127_1981673_22 Transcriptional regulator IclR K13641 - - 0.0000000000000000000000000000000000000000000000003001 186.0
TH2_k127_1981673_23 epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000005283 146.0
TH2_k127_1981673_24 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.00000000000000000000000000000000008192 141.0
TH2_k127_1981673_25 Asp/Glu/Hydantoin racemase K01799 - 5.2.1.1 0.00000000000000000000000000000004797 132.0
TH2_k127_1981673_26 GYD domain - - - 0.0000000000000000000000126 102.0
TH2_k127_1981673_27 acyl-coa dehydrogenase - - - 0.00000000000000000000004209 100.0
TH2_k127_1981673_28 Ethyl tert-butyl ether degradation EthD - - - 0.0000000000000000001249 92.0
TH2_k127_1981673_29 - - - - 0.000000000000002482 79.0
TH2_k127_1981673_3 Aldehyde oxidase and xanthine dehydrogenase K00087,K03520 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 420.0
TH2_k127_1981673_30 acyl-coa dehydrogenase - - - 0.000000000000003782 75.0
TH2_k127_1981673_31 acyl-coa dehydrogenase - - - 0.000000000002573 66.0
TH2_k127_1981673_32 Glycogen debranching enzyme K00568 - 2.1.1.222,2.1.1.64 0.00000000004961 74.0
TH2_k127_1981673_33 acyl-coa dehydrogenase - - - 0.000000005303 58.0
TH2_k127_1981673_34 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000001487 57.0
TH2_k127_1981673_4 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 362.0
TH2_k127_1981673_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 348.0
TH2_k127_1981673_6 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 324.0
TH2_k127_1981673_7 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 326.0
TH2_k127_1981673_8 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 314.0
TH2_k127_1981673_9 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 314.0
TH2_k127_204035_0 urocanate hydratase activity K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 1.418e-271 844.0
TH2_k127_204035_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 594.0
TH2_k127_204035_10 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 358.0
TH2_k127_204035_11 peptidyl-tyrosine sulfation K03217,K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 362.0
TH2_k127_204035_12 PFAM Formiminotransferase K00603 - 2.1.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 353.0
TH2_k127_204035_13 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 349.0
TH2_k127_204035_14 L-phenylalanine transmembrane transporter activity K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 323.0
TH2_k127_204035_15 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 304.0
TH2_k127_204035_16 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 305.0
TH2_k127_204035_17 extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 291.0
TH2_k127_204035_18 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 286.0
TH2_k127_204035_19 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006872 281.0
TH2_k127_204035_2 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 563.0
TH2_k127_204035_20 PFAM Methionine synthase, B12-binding module, cap domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001311 210.0
TH2_k127_204035_21 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.000000000000000000000000000000000000000000000000004759 185.0
TH2_k127_204035_22 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000005618 180.0
TH2_k127_204035_23 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000003044 169.0
TH2_k127_204035_24 SMART AAA ATPase - - - 0.000000000000000000000000000000000000001711 167.0
TH2_k127_204035_25 - - - - 0.000000000000000000000000000009496 120.0
TH2_k127_204035_26 SMART chemotaxis sensory transducer, histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000006303 130.0
TH2_k127_204035_27 Bacterial DNA-binding protein K03530 - - 0.00000000000000000000000159 106.0
TH2_k127_204035_28 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000002261 108.0
TH2_k127_204035_29 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000002077 107.0
TH2_k127_204035_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 497.0
TH2_k127_204035_30 Pas domain s-box - - - 0.000000000000003228 91.0
TH2_k127_204035_31 translation initiation factor activity K08086 - - 0.00001088 51.0
TH2_k127_204035_32 energy transducer activity K03832 - - 0.00003149 46.0
TH2_k127_204035_33 Resolvase, N terminal domain K07450 - - 0.00009998 48.0
TH2_k127_204035_34 - - - - 0.0003703 43.0
TH2_k127_204035_35 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0005282 52.0
TH2_k127_204035_4 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 470.0
TH2_k127_204035_5 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 458.0
TH2_k127_204035_6 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 451.0
TH2_k127_204035_7 mannitol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 433.0
TH2_k127_204035_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 418.0
TH2_k127_204035_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 366.0
TH2_k127_2267661_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 7.178e-208 656.0
TH2_k127_2267661_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 303.0
TH2_k127_2267661_2 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000004697 234.0
TH2_k127_2267661_3 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000004503 171.0
TH2_k127_2267661_4 RNA recognition motif - - - 0.0000000000000000000000000009097 116.0
TH2_k127_2267661_5 translation release factor activity - - - 0.000000005986 59.0
TH2_k127_2267661_6 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.000003537 50.0
TH2_k127_2271626_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 502.0
TH2_k127_2271626_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 488.0
TH2_k127_2271626_10 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 356.0
TH2_k127_2271626_11 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 320.0
TH2_k127_2271626_12 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 317.0
TH2_k127_2271626_13 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001895 280.0
TH2_k127_2271626_14 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001251 267.0
TH2_k127_2271626_15 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005348 263.0
TH2_k127_2271626_16 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000001091 263.0
TH2_k127_2271626_17 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001222 245.0
TH2_k127_2271626_18 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000001711 231.0
TH2_k127_2271626_19 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000005535 213.0
TH2_k127_2271626_2 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 477.0
TH2_k127_2271626_20 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000005923 206.0
TH2_k127_2271626_21 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000002142 188.0
TH2_k127_2271626_22 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000004036 185.0
TH2_k127_2271626_23 Oxidoreductase molybdopterin binding domain K07147 - - 0.000000000000000000000000000000000000000000000000226 183.0
TH2_k127_2271626_24 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000001724 162.0
TH2_k127_2271626_25 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000001672 157.0
TH2_k127_2271626_26 HIT domain K02503 - - 0.000000000000000000000000000000000000000959 150.0
TH2_k127_2271626_27 Phage-related replication protein - - - 0.00000000000000000000000000000000000002766 153.0
TH2_k127_2271626_28 TatD related DNase K03424 - - 0.000000000000000000000000000000000001337 148.0
TH2_k127_2271626_29 PFAM Class I peptide chain release factor - - - 0.000000000000000000000000000000000019 139.0
TH2_k127_2271626_3 Rhodanese Homology Domain K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 477.0
TH2_k127_2271626_30 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000001785 85.0
TH2_k127_2271626_31 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.000000000002821 73.0
TH2_k127_2271626_32 Cupin domain K11312 - - 0.00000001381 57.0
TH2_k127_2271626_33 Belongs to the 'phage' integrase family K04763 - - 0.00000005894 54.0
TH2_k127_2271626_4 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 458.0
TH2_k127_2271626_5 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 396.0
TH2_k127_2271626_6 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 395.0
TH2_k127_2271626_7 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 401.0
TH2_k127_2271626_8 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 389.0
TH2_k127_2271626_9 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 355.0
TH2_k127_2288867_0 PFAM Asparagine synthase K01953 - 6.3.5.4 1.478e-220 701.0
TH2_k127_2288867_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 470.0
TH2_k127_2288867_11 transglycosylase K08309 - - 0.0000007086 59.0
TH2_k127_2288867_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 458.0
TH2_k127_2288867_3 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 447.0
TH2_k127_2288867_4 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 356.0
TH2_k127_2288867_5 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 317.0
TH2_k127_2288867_6 DnaJ molecular chaperone homology domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001445 274.0
TH2_k127_2288867_7 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001366 260.0
TH2_k127_2288867_8 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000001306 190.0
TH2_k127_2288867_9 PAP2 superfamily K19302 - 3.6.1.27 0.000000000000000000000000000004681 128.0
TH2_k127_231159_0 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 489.0
TH2_k127_231159_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 374.0
TH2_k127_231159_2 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000309 100.0
TH2_k127_2357926_0 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000142 256.0
TH2_k127_2357926_1 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000003017 124.0
TH2_k127_2357926_2 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000004554 109.0
TH2_k127_2357926_3 Amidohydrolase family - - - 0.0000002747 55.0
TH2_k127_236823_0 PFAM 2-nitropropane dioxygenase NPD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 608.0
TH2_k127_236823_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 546.0
TH2_k127_236823_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 353.0
TH2_k127_236823_3 Protein of unknown function (DUF559) - - - 0.00000000000000000006876 90.0
TH2_k127_236823_4 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000004227 84.0
TH2_k127_236823_5 Protein of unknown function (DUF559) - - - 0.000002095 50.0
TH2_k127_2393779_0 CoA binding domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 596.0
TH2_k127_2393779_1 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 461.0
TH2_k127_2393779_10 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000002002 104.0
TH2_k127_2393779_11 conserved protein (DUF2249) K07322 - - 0.0000000000000000000005181 98.0
TH2_k127_2393779_12 - - - - 0.00000000000000000000816 97.0
TH2_k127_2393779_13 Domain of unknown function (DUF1858) - - - 0.0000000000000000001943 91.0
TH2_k127_2393779_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000001279 63.0
TH2_k127_2393779_15 - - - - 0.0006317 43.0
TH2_k127_2393779_2 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 295.0
TH2_k127_2393779_3 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007167 278.0
TH2_k127_2393779_4 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005711 231.0
TH2_k127_2393779_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001034 218.0
TH2_k127_2393779_6 Pectinacetylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000001458 230.0
TH2_k127_2393779_7 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000001582 203.0
TH2_k127_2393779_8 Cupin 2 conserved barrel domain - - - 0.00000000000000000000000000001183 125.0
TH2_k127_2394522_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 9.074e-195 614.0
TH2_k127_2394522_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 507.0
TH2_k127_2394522_10 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000001461 243.0
TH2_k127_2394522_11 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000003259 237.0
TH2_k127_2394522_12 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000002581 192.0
TH2_k127_2394522_13 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000141 167.0
TH2_k127_2394522_14 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000003132 164.0
TH2_k127_2394522_15 Thioesterase superfamily K02614 - - 0.000000000000000000002589 99.0
TH2_k127_2394522_16 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000003396 49.0
TH2_k127_2394522_17 Plasmid stability protein K21495 - - 0.0003504 44.0
TH2_k127_2394522_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 468.0
TH2_k127_2394522_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 456.0
TH2_k127_2394522_4 Electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 400.0
TH2_k127_2394522_5 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 364.0
TH2_k127_2394522_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000473 282.0
TH2_k127_2394522_7 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007079 261.0
TH2_k127_2394522_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002045 258.0
TH2_k127_2394522_9 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000008934 239.0
TH2_k127_2409315_0 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000003795 111.0
TH2_k127_2409315_1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000001744 99.0
TH2_k127_2409315_2 PIN domain - - - 0.00000000000000000004371 95.0
TH2_k127_2409315_3 TIGRFAM looped-hinge helix DNA binding domain, AbrB family - - - 0.00000000007996 66.0
TH2_k127_2409315_4 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000001996 56.0
TH2_k127_2436873_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 484.0
TH2_k127_2436873_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 425.0
TH2_k127_2436873_10 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000001303 77.0
TH2_k127_2436873_2 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 405.0
TH2_k127_2436873_3 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 323.0
TH2_k127_2436873_4 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000009467 180.0
TH2_k127_2436873_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000003524 147.0
TH2_k127_2436873_6 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000003861 132.0
TH2_k127_2436873_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000004528 134.0
TH2_k127_2436873_8 DNA polymerase - - - 0.0000000000000000000000000000421 118.0
TH2_k127_2436873_9 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000001192 96.0
TH2_k127_245189_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 515.0
TH2_k127_245189_1 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000004799 242.0
TH2_k127_245189_2 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.00000000000000003376 81.0
TH2_k127_245189_3 acetyl coenzyme A synthetase - - - 0.00000000000882 72.0
TH2_k127_2457926_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K00355,K05587,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 5.221e-289 896.0
TH2_k127_2457926_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 631.0
TH2_k127_2457926_2 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 545.0
TH2_k127_2457926_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007629 380.0
TH2_k127_2457926_4 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 310.0
TH2_k127_2457926_5 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002213 281.0
TH2_k127_2470277_0 Belongs to the carbamoyltransferase HypF family K04656 - - 1.074e-262 830.0
TH2_k127_2470277_1 PFAM Nickel-dependent hydrogenase, large subunit K06281 - 1.12.99.6 7.024e-204 643.0
TH2_k127_2470277_10 HupF/HypC family K04653 - - 0.000000000000000000549 89.0
TH2_k127_2470277_11 Rhodanese Homology Domain - - - 0.00000007449 60.0
TH2_k127_2470277_2 Hydrogenase expression formation protein hypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 446.0
TH2_k127_2470277_3 small subunit K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 402.0
TH2_k127_2470277_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 326.0
TH2_k127_2470277_5 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001775 270.0
TH2_k127_2470277_6 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000003646 175.0
TH2_k127_2470277_7 hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000008683 141.0
TH2_k127_2470277_8 - - - - 0.000000000000000000000000000000006312 138.0
TH2_k127_2470277_9 - - - - 0.0000000000000000000000000001509 119.0
TH2_k127_2529634_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 532.0
TH2_k127_2529634_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 453.0
TH2_k127_2529634_2 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 445.0
TH2_k127_2529634_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000004287 224.0
TH2_k127_257764_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 494.0
TH2_k127_257764_1 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 377.0
TH2_k127_257764_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 359.0
TH2_k127_257764_3 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002566 247.0
TH2_k127_257764_4 PFAM PilT protein domain protein - - - 0.0000000000000000000000000000000000000000007372 160.0
TH2_k127_257764_5 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000009957 130.0
TH2_k127_257764_6 Transcription termination factor nusG - - - 0.0000000000000000000000000006685 119.0
TH2_k127_257764_7 Capsular exopolysaccharide family - - - 0.0000000000000000000000000008142 118.0
TH2_k127_257764_8 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000000001275 92.0
TH2_k127_257764_9 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00004461 47.0
TH2_k127_2610007_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1652.0
TH2_k127_2610007_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 416.0
TH2_k127_2610007_10 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.00000000000000000000000006825 111.0
TH2_k127_2610007_11 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000002603 98.0
TH2_k127_2610007_12 - - - - 0.000000000000001677 82.0
TH2_k127_2610007_13 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.000000004152 58.0
TH2_k127_2610007_2 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 383.0
TH2_k127_2610007_3 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 349.0
TH2_k127_2610007_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 331.0
TH2_k127_2610007_5 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 312.0
TH2_k127_2610007_6 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000009097 201.0
TH2_k127_2610007_7 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000003115 151.0
TH2_k127_2610007_8 - - - - 0.00000000000000000000000000000000004925 139.0
TH2_k127_2610007_9 ThiS family K03636 - - 0.00000000000000000000000003634 115.0
TH2_k127_2647766_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.0 1064.0
TH2_k127_2647766_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 608.0
TH2_k127_2647766_10 - - - - 0.00000003783 59.0
TH2_k127_2647766_11 - - - - 0.00007426 52.0
TH2_k127_2647766_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 430.0
TH2_k127_2647766_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 390.0
TH2_k127_2647766_4 Belongs to the Nudix hydrolase family. NudC subfamily K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 348.0
TH2_k127_2647766_5 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 299.0
TH2_k127_2647766_6 COG1233 Phytoene dehydrogenase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005653 288.0
TH2_k127_2647766_7 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007945 274.0
TH2_k127_2647766_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000112 277.0
TH2_k127_2647766_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.00000000000000007448 80.0
TH2_k127_2680699_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000553 286.0
TH2_k127_2680699_1 methyltransferase K05928 - 2.1.1.95 0.0000000000000000000000000000000000000009207 156.0
TH2_k127_2680699_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000006354 102.0
TH2_k127_2680699_3 PFAM Methyltransferase - - - 0.0000000000005289 72.0
TH2_k127_2685574_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.806e-278 875.0
TH2_k127_2685574_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 561.0
TH2_k127_2685574_10 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 315.0
TH2_k127_2685574_11 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 334.0
TH2_k127_2685574_12 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001085 272.0
TH2_k127_2685574_13 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001841 274.0
TH2_k127_2685574_14 abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004549 250.0
TH2_k127_2685574_15 Uroporphyrinogen-III synthase HemD K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000001324 245.0
TH2_k127_2685574_16 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000000000004109 218.0
TH2_k127_2685574_17 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000008893 204.0
TH2_k127_2685574_18 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000003183 196.0
TH2_k127_2685574_19 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000000004599 182.0
TH2_k127_2685574_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 520.0
TH2_k127_2685574_20 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000007414 166.0
TH2_k127_2685574_21 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000008388 172.0
TH2_k127_2685574_22 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000004037 159.0
TH2_k127_2685574_23 - - - - 0.00000000000000000000000000000000005974 139.0
TH2_k127_2685574_24 Tetratricopeptide repeat - - - 0.000000000000000000000000000000009472 135.0
TH2_k127_2685574_25 Thioredoxin-like - - - 0.00000000000000000000000001248 117.0
TH2_k127_2685574_26 Domain of unknown function (DUF4115) - - - 0.0000000000000002732 90.0
TH2_k127_2685574_27 COG0457 FOG TPR repeat - - - 0.000001674 59.0
TH2_k127_2685574_28 shape-determining protein MreD K03571 - - 0.00001138 54.0
TH2_k127_2685574_29 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.0002416 44.0
TH2_k127_2685574_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 494.0
TH2_k127_2685574_4 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 478.0
TH2_k127_2685574_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 414.0
TH2_k127_2685574_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 359.0
TH2_k127_2685574_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 359.0
TH2_k127_2685574_8 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 346.0
TH2_k127_2685574_9 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 338.0
TH2_k127_2718059_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.085e-230 727.0
TH2_k127_2718059_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 506.0
TH2_k127_2718059_10 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 317.0
TH2_k127_2718059_11 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 305.0
TH2_k127_2718059_12 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 300.0
TH2_k127_2718059_13 branched-chain amino acid K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 295.0
TH2_k127_2718059_14 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 299.0
TH2_k127_2718059_15 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 286.0
TH2_k127_2718059_16 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008863 276.0
TH2_k127_2718059_17 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001329 269.0
TH2_k127_2718059_18 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001262 257.0
TH2_k127_2718059_19 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000275 254.0
TH2_k127_2718059_2 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 505.0
TH2_k127_2718059_20 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000572 251.0
TH2_k127_2718059_21 COG4177 ABC-type branched-chain amino acid transport system, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007835 248.0
TH2_k127_2718059_22 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000007252 220.0
TH2_k127_2718059_23 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000102 198.0
TH2_k127_2718059_24 PFAM MaoC domain protein dehydratase K17865 - 4.2.1.55 0.000000000000000000000000000000000000000000000000001037 186.0
TH2_k127_2718059_25 sequence-specific DNA binding K18830 - - 0.000000000000000000000000000000000000000000003769 167.0
TH2_k127_2718059_26 polynucleotide 5'-hydroxyl-kinase activity K06947 - - 0.000000000000000000000000000000000003929 149.0
TH2_k127_2718059_27 COG2963 Transposase and inactivated derivatives K07483 - - 0.0000000000000004051 81.0
TH2_k127_2718059_28 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000001476 57.0
TH2_k127_2718059_29 - - - - 0.000001554 55.0
TH2_k127_2718059_3 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 398.0
TH2_k127_2718059_30 Helix-turn-helix domain - - - 0.0001561 44.0
TH2_k127_2718059_4 alcohol dehydrogenase K19954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 372.0
TH2_k127_2718059_5 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 358.0
TH2_k127_2718059_6 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 356.0
TH2_k127_2718059_7 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 355.0
TH2_k127_2718059_8 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 348.0
TH2_k127_2718059_9 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 333.0
TH2_k127_2725997_0 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 590.0
TH2_k127_2725997_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 473.0
TH2_k127_2725997_2 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004678 257.0
TH2_k127_2725997_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002215 241.0
TH2_k127_2725997_4 3-hydroxyacyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003255 243.0
TH2_k127_2725997_5 Glutathione peroxidase - - - 0.00000000000000000000000000000000006432 141.0
TH2_k127_2725997_6 NAD+ diphosphatase activity K01515,K03426 - 3.6.1.13,3.6.1.22 0.00000008168 64.0
TH2_k127_2725997_7 Domain of unknown function (DUF4282) - - - 0.000001043 57.0
TH2_k127_2734337_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 1.307e-236 741.0
TH2_k127_2734337_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 602.0
TH2_k127_2734337_2 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 310.0
TH2_k127_2734337_3 Glycine cleavage system H protein K02437 - - 0.0000000000000000000000000000000000000000000000004773 179.0
TH2_k127_2734337_4 Nitrate reductase gamma subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000008743 170.0
TH2_k127_2734337_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000001026 171.0
TH2_k127_2744409_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 2.5e-323 998.0
TH2_k127_2744409_1 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 552.0
TH2_k127_2744409_10 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 319.0
TH2_k127_2744409_11 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 304.0
TH2_k127_2744409_12 Neisseria PilC beta-propeller domain K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 316.0
TH2_k127_2744409_13 histidine kinase, HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001874 293.0
TH2_k127_2744409_14 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007448 275.0
TH2_k127_2744409_15 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006408 259.0
TH2_k127_2744409_16 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000002373 249.0
TH2_k127_2744409_17 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001511 241.0
TH2_k127_2744409_18 Neisseria PilC beta-propeller domain K02674 - - 0.0000000000000000000000000000000000000000000000000000000007768 231.0
TH2_k127_2744409_19 COG0438 Glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001566 215.0
TH2_k127_2744409_2 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 445.0
TH2_k127_2744409_20 Neisseria PilC beta-propeller domain K02674 - - 0.0000000000000000000000000000000000000000000000000000001411 224.0
TH2_k127_2744409_21 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000005261 201.0
TH2_k127_2744409_22 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000002827 196.0
TH2_k127_2744409_23 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000001458 169.0
TH2_k127_2744409_24 PFAM Roadblock LC7 - - - 0.00000000000000000000000000000005125 129.0
TH2_k127_2744409_25 Winged helix-turn-helix DNA-binding - - - 0.0000000000000000000000000002551 121.0
TH2_k127_2744409_26 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000005566 108.0
TH2_k127_2744409_27 Tetratricopeptide repeats - - - 0.00000000000000000000002819 111.0
TH2_k127_2744409_28 COG3209 Rhs family protein - - - 0.0000000000000000002885 98.0
TH2_k127_2744409_29 pilus assembly protein PilW - - - 0.00000000000000000442 94.0
TH2_k127_2744409_3 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 446.0
TH2_k127_2744409_30 pilus assembly protein PilW - - - 0.00000000000000003986 93.0
TH2_k127_2744409_31 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000004108 77.0
TH2_k127_2744409_32 Tetratricopeptide repeat - - - 0.00000000000004424 83.0
TH2_k127_2744409_33 Pilin (bacterial filament) K02650,K02655 - - 0.00000000000008506 77.0
TH2_k127_2744409_34 Prokaryotic N-terminal methylation motif K02671 - - 0.0000000002284 66.0
TH2_k127_2744409_35 Prokaryotic N-terminal methylation motif - - - 0.000000002453 63.0
TH2_k127_2744409_36 Type II transport protein GspH K08084 - - 0.00000000328 64.0
TH2_k127_2744409_37 Type II transport protein GspH K08084 - - 0.000000005924 63.0
TH2_k127_2744409_38 PilX N-terminal - - - 0.000000005943 63.0
TH2_k127_2744409_39 PilX N-terminal - - - 0.00000003593 61.0
TH2_k127_2744409_4 Neisseria PilC beta-propeller domain K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 453.0
TH2_k127_2744409_40 Prokaryotic N-terminal methylation motif K08084 - - 0.00000003922 61.0
TH2_k127_2744409_41 type IV pilus modification protein PilV K02458,K02671 - - 0.00000006533 59.0
TH2_k127_2744409_42 pilus assembly protein PilW K02672 - - 0.000001386 58.0
TH2_k127_2744409_43 TIGRFAM Pilus modification type IV, PilV K02671 - - 0.00001345 52.0
TH2_k127_2744409_44 PilX N-terminal - - - 0.00001653 53.0
TH2_k127_2744409_45 pilus assembly protein PilW K02672 - - 0.00004892 54.0
TH2_k127_2744409_46 PilX N-terminal - - - 0.0009897 48.0
TH2_k127_2744409_5 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 426.0
TH2_k127_2744409_6 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 422.0
TH2_k127_2744409_7 Evidence 2b Function of strongly homologous gene K01990,K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 376.0
TH2_k127_2744409_8 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 353.0
TH2_k127_2744409_9 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 352.0
TH2_k127_2745406_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 435.0
TH2_k127_2745406_1 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 350.0
TH2_k127_2745406_2 peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000002169 146.0
TH2_k127_2745406_3 CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000003117 119.0
TH2_k127_2745406_4 Domain of unknown function (DUF4410) - - - 0.00000008204 61.0
TH2_k127_2745406_5 - - - - 0.00002573 54.0
TH2_k127_2805085_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.06e-302 944.0
TH2_k127_2805085_1 penicillin amidase K01434 - 3.5.1.11 5.223e-220 710.0
TH2_k127_2805085_10 Belongs to the helicase family. UvrD subfamily - - - 0.0000000000000000000000000000000000000000000000003482 188.0
TH2_k127_2805085_11 ACT domain - - - 0.0000000000000000000000000000000000000000000002628 171.0
TH2_k127_2805085_12 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000000007826 89.0
TH2_k127_2805085_13 Transposase IS200 like K07491 - - 0.00000000000000001499 87.0
TH2_k127_2805085_2 CoA binding domain K01905 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 570.0
TH2_k127_2805085_3 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 504.0
TH2_k127_2805085_4 PFAM aminotransferase, class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 504.0
TH2_k127_2805085_5 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 411.0
TH2_k127_2805085_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 382.0
TH2_k127_2805085_7 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 356.0
TH2_k127_2805085_8 PFAM ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001925 262.0
TH2_k127_2805085_9 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000001738 211.0
TH2_k127_2805307_0 Tim44 K02117,K08678,K11646,K15539,K17835,K21636 - 1.1.98.6,1.4.1.24,3.6.3.14,3.6.3.15,4.1.1.35,4.1.99.20 1.459e-217 712.0
TH2_k127_2805307_1 gluconate transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 587.0
TH2_k127_2805307_10 SAM-dependent RNA methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001535 215.0
TH2_k127_2805307_11 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000393 211.0
TH2_k127_2805307_12 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000002743 169.0
TH2_k127_2805307_13 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000364 129.0
TH2_k127_2805307_14 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000006143 128.0
TH2_k127_2805307_15 KH domain K06960 - - 0.00000000000000000000000000003961 118.0
TH2_k127_2805307_16 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000005112 106.0
TH2_k127_2805307_18 - - - - 0.0000000000001323 76.0
TH2_k127_2805307_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 560.0
TH2_k127_2805307_3 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 543.0
TH2_k127_2805307_4 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 520.0
TH2_k127_2805307_5 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 499.0
TH2_k127_2805307_6 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 383.0
TH2_k127_2805307_7 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 314.0
TH2_k127_2805307_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000001848 252.0
TH2_k127_2805307_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000005116 224.0
TH2_k127_2916508_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.00000000000000000000000000003354 122.0
TH2_k127_2916508_1 Transcriptional regulator, Crp Fnr family K03321,K10914 - - 0.000000001677 64.0
TH2_k127_2916508_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000002587 64.0
TH2_k127_2925233_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 536.0
TH2_k127_2925233_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 416.0
TH2_k127_2925233_2 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 372.0
TH2_k127_2925233_3 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 346.0
TH2_k127_2925233_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000002197 141.0
TH2_k127_2925233_5 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000005673 111.0
TH2_k127_2925233_6 Conserved carboxylase domain K00627,K01571,K01960,K03416,K20140 - 2.1.3.1,2.3.1.12,4.1.1.3,6.4.1.1,6.4.1.7 0.0000001251 53.0
TH2_k127_301843_0 membrane - - - 0.0000000000000000000000000503 112.0
TH2_k127_301843_1 reverse transcriptase - - - 0.000000000002801 68.0
TH2_k127_301843_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000007721 69.0
TH2_k127_301843_3 Virulence factor BrkB - - - 0.0000000004355 70.0
TH2_k127_301843_4 CopG antitoxin of type II toxin-antitoxin system - - - 0.00000002132 58.0
TH2_k127_301843_5 viral genome integration into host DNA K04763 - - 0.000000232 53.0
TH2_k127_301843_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000009727 54.0
TH2_k127_3056156_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 341.0
TH2_k127_3056156_1 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003048 259.0
TH2_k127_3056156_2 Zn-dependent hydrolases including glyoxylases-like protein - - - 0.00000000000000000000000000000000001642 147.0
TH2_k127_3056156_3 Putative regulatory protein - - - 0.0000000000004431 70.0
TH2_k127_307208_0 Endoribonuclease that initiates mRNA decay K18682 - - 2.835e-217 686.0
TH2_k127_307208_1 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 1.043e-213 678.0
TH2_k127_307208_10 - - - - 0.00000000000000000000003818 99.0
TH2_k127_307208_11 Belongs to the peptidase S8 family K13276 GO:0005575,GO:0005576 - 0.00000000000000000001608 107.0
TH2_k127_307208_12 - - - - 0.000000000000001327 79.0
TH2_k127_307208_13 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000002678 70.0
TH2_k127_307208_14 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000006912 59.0
TH2_k127_307208_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 522.0
TH2_k127_307208_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 504.0
TH2_k127_307208_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 430.0
TH2_k127_307208_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000944 405.0
TH2_k127_307208_6 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 324.0
TH2_k127_307208_7 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005036 278.0
TH2_k127_307208_8 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006101 255.0
TH2_k127_307208_9 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000005059 156.0
TH2_k127_3079543_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1230.0
TH2_k127_3079543_1 ABC transporter transmembrane region K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 404.0
TH2_k127_3079543_10 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000003071 151.0
TH2_k127_3079543_11 - - - - 0.0000000000000000000000000000000001129 139.0
TH2_k127_3079543_13 Transcription factor zinc-finger K09981 - - 0.00000000000000000000000002365 110.0
TH2_k127_3079543_14 Cold shock protein K03704 - - 0.000000000000000000000003667 103.0
TH2_k127_3079543_15 PIN domain - - - 0.00000000000000000000009482 102.0
TH2_k127_3079543_16 PBS lyase HEAT-like repeat K05384 - - 0.0000007262 63.0
TH2_k127_3079543_17 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000004299 53.0
TH2_k127_3079543_2 SMART Chromosomal replication initiator DnaA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 372.0
TH2_k127_3079543_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 312.0
TH2_k127_3079543_4 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001963 271.0
TH2_k127_3079543_5 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000004624 249.0
TH2_k127_3079543_6 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000004692 174.0
TH2_k127_3079543_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000006054 177.0
TH2_k127_3079543_8 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000001441 148.0
TH2_k127_3079543_9 Histidine kinase - - - 0.0000000000000000000000000000000000000263 157.0
TH2_k127_3084805_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 2.894e-207 650.0
TH2_k127_3084805_1 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 559.0
TH2_k127_3084805_2 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 534.0
TH2_k127_3084805_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886 430.0
TH2_k127_3084805_4 Bacterial type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 383.0
TH2_k127_3084805_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006059 254.0
TH2_k127_3084805_6 PFAM Cytochrome b5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002798 257.0
TH2_k127_3084805_7 Putative heavy-metal chelation K09138 - - 0.00000000000000000000000000000000000000000000000000000000000001165 224.0
TH2_k127_3084805_8 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000003848 183.0
TH2_k127_3090688_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 479.0
TH2_k127_3090688_1 Type II secretory pathway component ExeA K02450,K12283 - - 0.0000000000000000000000000000000000000004707 162.0
TH2_k127_3090688_2 - - - - 0.0001025 46.0
TH2_k127_3123480_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1861.0
TH2_k127_3123480_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 9.04e-321 990.0
TH2_k127_3123480_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 341.0
TH2_k127_3123480_3 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008376 256.0
TH2_k127_3123480_4 Ribosomal protein L11/L12 K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000493 224.0
TH2_k127_3123480_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000005326 164.0
TH2_k127_3123480_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864,K02935 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000885 148.0
TH2_k127_3123480_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000001827 91.0
TH2_k127_3123480_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000006926 77.0
TH2_k127_3123480_9 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000003497 67.0
TH2_k127_3123556_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 422.0
TH2_k127_3123556_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 334.0
TH2_k127_3123556_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000004943 156.0
TH2_k127_3123556_11 Ribosomal proteins 50S L24/mitochondrial 39S L24 K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000006057 147.0
TH2_k127_3123556_12 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000001499 135.0
TH2_k127_3123556_13 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000005019 118.0
TH2_k127_3123556_14 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001194 117.0
TH2_k127_3123556_15 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000247 102.0
TH2_k127_3123556_16 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000006926 77.0
TH2_k127_3123556_17 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000007312 79.0
TH2_k127_3123556_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000181 282.0
TH2_k127_3123556_3 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001003 256.0
TH2_k127_3123556_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003521 250.0
TH2_k127_3123556_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001938 216.0
TH2_k127_3123556_6 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001511 211.0
TH2_k127_3123556_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000005913 203.0
TH2_k127_3123556_8 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001503 178.0
TH2_k127_3123556_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000001458 165.0
TH2_k127_3161844_0 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 481.0
TH2_k127_3161844_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 419.0
TH2_k127_3161844_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005534 260.0
TH2_k127_3161844_3 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000005425 85.0
TH2_k127_3171015_0 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 584.0
TH2_k127_3171015_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 308.0
TH2_k127_3171015_2 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 309.0
TH2_k127_3171015_3 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004845 245.0
TH2_k127_3171015_4 spore germination K16928 - - 0.00000000000000000000000000000000000000000000001513 179.0
TH2_k127_3171015_5 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000004341 162.0
TH2_k127_31823_0 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01615 - 4.1.1.70 8.623e-307 947.0
TH2_k127_31823_1 Psort location CytoplasmicMembrane, score - - - 2.691e-258 816.0
TH2_k127_31823_10 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 310.0
TH2_k127_31823_11 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 304.0
TH2_k127_31823_12 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 293.0
TH2_k127_31823_13 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000003221 267.0
TH2_k127_31823_14 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000003476 232.0
TH2_k127_31823_15 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000004866 238.0
TH2_k127_31823_16 FAD binding domain in molybdopterin dehydrogenase K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000007047 223.0
TH2_k127_31823_17 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000002193 206.0
TH2_k127_31823_18 Prephenate dehydrogenase K00210 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000001485 195.0
TH2_k127_31823_19 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000003212 171.0
TH2_k127_31823_2 aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 498.0
TH2_k127_31823_20 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000003689 177.0
TH2_k127_31823_21 COG1233 Phytoene dehydrogenase and related proteins K09516 - 1.3.99.23 0.000000000000000000000000000000006915 145.0
TH2_k127_31823_22 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000003434 118.0
TH2_k127_31823_23 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.000000000000000000003545 99.0
TH2_k127_31823_24 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000001345 91.0
TH2_k127_31823_25 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000279 70.0
TH2_k127_31823_26 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000001409 65.0
TH2_k127_31823_27 - - - - 0.000003047 55.0
TH2_k127_31823_28 Histidine kinase HAMP K02482 - 2.7.13.3 0.00004955 49.0
TH2_k127_31823_3 ABC transporter K02017,K06857 - 3.6.3.29,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 466.0
TH2_k127_31823_4 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 445.0
TH2_k127_31823_5 Bacterial extracellular solute-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 423.0
TH2_k127_31823_6 TIGRFAM DNA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 392.0
TH2_k127_31823_7 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 358.0
TH2_k127_31823_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 336.0
TH2_k127_31823_9 mannitol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 343.0
TH2_k127_3200307_0 Oxidoreductase family, NAD-binding Rossmann fold K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 364.0
TH2_k127_3200307_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 314.0
TH2_k127_3200307_2 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000003556 222.0
TH2_k127_3200307_3 transferase hexapeptide K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000005139 177.0
TH2_k127_3200307_4 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000134 124.0
TH2_k127_3200307_5 lipolytic protein G-D-S-L family - - - 0.000000000000000749 84.0
TH2_k127_320637_0 Psort location Cytoplasmic, score - - - 0.0 1621.0
TH2_k127_320637_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 432.0
TH2_k127_320637_2 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 397.0
TH2_k127_320637_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 328.0
TH2_k127_320637_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 325.0
TH2_k127_320637_5 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000001176 229.0
TH2_k127_320637_6 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000009794 220.0
TH2_k127_320637_7 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000001256 111.0
TH2_k127_320637_8 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000001003 72.0
TH2_k127_3227937_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 604.0
TH2_k127_3227937_1 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 421.0
TH2_k127_3227937_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 384.0
TH2_k127_3230925_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 7.007e-255 795.0
TH2_k127_3230925_1 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 598.0
TH2_k127_3230925_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000003789 147.0
TH2_k127_3230925_11 - - - - 0.000000000000000000000000000000001437 132.0
TH2_k127_3230925_12 NAD(P)H dehydrogenase (quinone) activity - - - 0.0000000000000000000000000006897 113.0
TH2_k127_3230925_13 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000642 108.0
TH2_k127_3230925_14 general stress protein - - - 0.0000000000000000006072 93.0
TH2_k127_3230925_15 B3 4 domain protein - - - 0.00000000000002583 81.0
TH2_k127_3230925_16 Regulatory protein, FmdB family - - - 0.0000005418 56.0
TH2_k127_3230925_17 Tautomerase enzyme K01821 - 5.3.2.6 0.000001003 53.0
TH2_k127_3230925_2 PFAM 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 556.0
TH2_k127_3230925_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 317.0
TH2_k127_3230925_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005468 269.0
TH2_k127_3230925_5 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001002 261.0
TH2_k127_3230925_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001015 258.0
TH2_k127_3230925_7 Virulence activator alpha C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000001044 235.0
TH2_k127_3230925_8 PFAM Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.0000000000000000000000000000000000000000000000000000002532 204.0
TH2_k127_3230925_9 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000000000000000000000000004584 187.0
TH2_k127_3231443_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1180.0
TH2_k127_3231443_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 8.518e-230 726.0
TH2_k127_3231443_10 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 377.0
TH2_k127_3231443_11 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 361.0
TH2_k127_3231443_12 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 357.0
TH2_k127_3231443_13 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 342.0
TH2_k127_3231443_14 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 325.0
TH2_k127_3231443_15 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 300.0
TH2_k127_3231443_16 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 297.0
TH2_k127_3231443_17 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 287.0
TH2_k127_3231443_18 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005943 282.0
TH2_k127_3231443_19 NlpC/P60 family K19223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007323 269.0
TH2_k127_3231443_2 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 2.2e-214 692.0
TH2_k127_3231443_20 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001495 262.0
TH2_k127_3231443_21 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000002141 255.0
TH2_k127_3231443_22 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001056 264.0
TH2_k127_3231443_23 ABC transporter K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000007939 242.0
TH2_k127_3231443_24 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000001597 241.0
TH2_k127_3231443_25 pfam nlp p60 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002231 250.0
TH2_k127_3231443_26 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000008973 226.0
TH2_k127_3231443_27 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000006951 221.0
TH2_k127_3231443_28 DIM6 NTAB family - - - 0.00000000000000000000000000000000000000000000000000000006388 202.0
TH2_k127_3231443_29 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000001541 204.0
TH2_k127_3231443_3 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 4.792e-210 666.0
TH2_k127_3231443_30 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000001734 182.0
TH2_k127_3231443_31 Cobalt ABC transporter K02008 - - 0.000000000000000000000000000000000000000000005688 172.0
TH2_k127_3231443_32 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000005144 158.0
TH2_k127_3231443_33 CoA binding domain K06929 - - 0.00000000000000000000000000000000000017 145.0
TH2_k127_3231443_34 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000001062 138.0
TH2_k127_3231443_35 Thioesterase superfamily - - - 0.0000000000000000000000000000007671 126.0
TH2_k127_3231443_36 - - - - 0.0000000000000000000000000000108 120.0
TH2_k127_3231443_37 Soluble P-type ATPase - - - 0.0000000000000000000000004281 111.0
TH2_k127_3231443_38 Radical SAM domain protein - - - 0.000000000000000000000003706 114.0
TH2_k127_3231443_39 lysyltransferase activity K07027 - - 0.00000000000000000000003194 111.0
TH2_k127_3231443_4 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 556.0
TH2_k127_3231443_40 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.0000000000000001856 83.0
TH2_k127_3231443_41 - - - - 0.0000000000006248 72.0
TH2_k127_3231443_43 Putative zinc-finger - - - 0.0001134 54.0
TH2_k127_3231443_44 Transposase, Mutator family - - - 0.0006651 42.0
TH2_k127_3231443_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 546.0
TH2_k127_3231443_6 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 470.0
TH2_k127_3231443_7 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 443.0
TH2_k127_3231443_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 426.0
TH2_k127_3231443_9 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 415.0
TH2_k127_3232247_0 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 601.0
TH2_k127_3232247_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 423.0
TH2_k127_3232247_11 PFAM UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.0000008539 55.0
TH2_k127_3232247_2 Cytochrome C biogenesis protein - - - 0.000000000000000000000000000000000000000000000000003975 201.0
TH2_k127_3232247_3 Domains HisKA, HATPase_c - - - 0.00000000000000000000000000000000000000000221 172.0
TH2_k127_3232247_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.000000000000000000000000000000003357 132.0
TH2_k127_3232247_5 GYD domain - - - 0.000000000000000000000000005858 113.0
TH2_k127_3232247_6 PFAM Thioredoxin K03671 - - 0.000000000000000000000003771 113.0
TH2_k127_3232247_7 AraC-like ligand binding domain - - - 0.000000000000007306 78.0
TH2_k127_3232247_9 Glutaredoxin K03676 - - 0.0000000000006092 69.0
TH2_k127_3290819_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 8.234e-232 746.0
TH2_k127_3290819_1 Tripartite tricarboxylate transporter TctA family - - - 5.966e-213 673.0
TH2_k127_3290819_10 PFAM ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004286 276.0
TH2_k127_3290819_11 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007043 272.0
TH2_k127_3290819_12 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003665 256.0
TH2_k127_3290819_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003373 260.0
TH2_k127_3290819_14 Cytidylyltransferase-like K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000002599 210.0
TH2_k127_3290819_15 ABC transporter substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000004597 188.0
TH2_k127_3290819_16 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000003339 144.0
TH2_k127_3290819_17 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000003548 140.0
TH2_k127_3290819_18 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000001175 139.0
TH2_k127_3290819_19 PFAM PilT protein domain protein - - - 0.0000000000000000000000000000000003042 136.0
TH2_k127_3290819_2 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 586.0
TH2_k127_3290819_20 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000007593 119.0
TH2_k127_3290819_21 RNA polymerase-binding protein DksA K06204 - - 0.000000000000000000000004167 108.0
TH2_k127_3290819_22 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000001687 106.0
TH2_k127_3290819_23 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672 - 1.21.4.2 0.000000000000000008964 86.0
TH2_k127_3290819_24 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000008113 68.0
TH2_k127_3290819_3 Aldehyde dehydrogenase family K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 563.0
TH2_k127_3290819_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 423.0
TH2_k127_3290819_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 419.0
TH2_k127_3290819_6 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 391.0
TH2_k127_3290819_7 Glycine reductase complex component B subunit gamma K10672 - 1.21.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 379.0
TH2_k127_3290819_8 Glycine/sarcosine/betaine reductase component B subunits K10671 - 1.21.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 326.0
TH2_k127_3290819_9 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 295.0
TH2_k127_3345901_0 PFAM Tannase and feruloyl esterase K21105 - 3.1.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 594.0
TH2_k127_3345901_1 Psort location CytoplasmicMembrane, score K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 584.0
TH2_k127_3345901_10 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 440.0
TH2_k127_3345901_11 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 434.0
TH2_k127_3345901_12 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 431.0
TH2_k127_3345901_13 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 433.0
TH2_k127_3345901_14 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 409.0
TH2_k127_3345901_15 LysR substrate binding domain K16135 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 394.0
TH2_k127_3345901_16 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 380.0
TH2_k127_3345901_17 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 382.0
TH2_k127_3345901_18 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 374.0
TH2_k127_3345901_19 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 359.0
TH2_k127_3345901_2 CoA binding domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 585.0
TH2_k127_3345901_20 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 364.0
TH2_k127_3345901_21 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 346.0
TH2_k127_3345901_22 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 351.0
TH2_k127_3345901_23 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 334.0
TH2_k127_3345901_24 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 305.0
TH2_k127_3345901_25 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 301.0
TH2_k127_3345901_26 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000322 287.0
TH2_k127_3345901_27 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007472 268.0
TH2_k127_3345901_28 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007317 252.0
TH2_k127_3345901_29 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009535 253.0
TH2_k127_3345901_3 domain, Protein K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 556.0
TH2_k127_3345901_30 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000002105 241.0
TH2_k127_3345901_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000057 237.0
TH2_k127_3345901_32 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001975 233.0
TH2_k127_3345901_33 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) K03386,K13279 GO:0000122,GO:0000187,GO:0000302,GO:0000303,GO:0000305,GO:0001775,GO:0001932,GO:0001934,GO:0002237,GO:0002252,GO:0002376,GO:0002520,GO:0002532,GO:0002536,GO:0002679,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0002831,GO:0002832,GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006357,GO:0006801,GO:0006950,GO:0006952,GO:0006954,GO:0006979,GO:0007162,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008283,GO:0008340,GO:0008379,GO:0008430,GO:0009056,GO:0009266,GO:0009408,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009636,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010259,GO:0010286,GO:0010310,GO:0010468,GO:0010556,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0019219,GO:0019220,GO:0019222,GO:0019430,GO:0022407,GO:0022408,GO:0023051,GO:0023056,GO:0023057,GO:0030155,GO:0030193,GO:0030194,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031399,GO:0031401,GO:0031664,GO:0031665,GO:0032088,GO:0032101,GO:0032102,GO:0032147,GO:0032268,GO:0032270,GO:0032496,GO:0032501,GO:0032502,GO:0032943,GO:0033554,GO:0033674,GO:0033993,GO:0034599,GO:0034614,GO:0042098,GO:0042110,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042542,GO:0042592,GO:0042737,GO:0042743,GO:0042744,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043207,GO:0043209,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043433,GO:0043523,GO:0043524,GO:0043549,GO:0043900,GO:0043901,GO:0044092,GO:0044093,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0045580,GO:0045581,GO:0045595,GO:0045596,GO:0045619,GO:0045620,GO:0045730,GO:0045859,GO:0045860,GO:0045892,GO:0045934,GO:0045937,GO:0046649,GO:0046651,GO:0046677,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048538,GO:0048583,GO:0048584,GO:0048585,GO:0048731,GO:0048732,GO:0048856,GO:0048872,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050818,GO:0050820,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0050878,GO:0050896,GO:0051090,GO:0051093,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051186,GO:0051187,GO:0051193,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051249,GO:0051250,GO:0051252,GO:0051253,GO:0051338,GO:0051347,GO:0051704,GO:0051707,GO:0051716,GO:0051920,GO:0055114,GO:0060255,GO:0060548,GO:0061041,GO:0065007,GO:0065008,GO:0065009,GO:0070661,GO:0070887,GO:0071450,GO:0071451,GO:0071900,GO:0071902,GO:0072593,GO:0080090,GO:0080134,GO:0090303,GO:0097237,GO:0098754,GO:0098869,GO:1900046,GO:1900048,GO:1901099,GO:1901214,GO:1901215,GO:1901700,GO:1901701,GO:1902105,GO:1902106,GO:1902531,GO:1902533,GO:1902679,GO:1903034,GO:1903036,GO:1903037,GO:1903038,GO:1903506,GO:1903507,GO:1903706,GO:1903707,GO:1990748,GO:2000026,GO:2000112,GO:2000113,GO:2000377,GO:2000378,GO:2001141,GO:2001233,GO:2001234,GO:2001236,GO:2001237,GO:2001239,GO:2001240 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000002406 232.0
TH2_k127_3345901_34 Protein of unknown function (DUF401) K09133 - - 0.000000000000000000000000000000000000000000000000000000000000000004217 241.0
TH2_k127_3345901_35 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000006371 229.0
TH2_k127_3345901_36 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000007564 225.0
TH2_k127_3345901_37 Sodium:alanine symporter family K03310 - - 0.00000000000000000000000000000000000000000000000000000000001847 217.0
TH2_k127_3345901_38 LUD domain - - - 0.000000000000000000000000000000000000000000000000000000007366 205.0
TH2_k127_3345901_39 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000004239 206.0
TH2_k127_3345901_4 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 553.0
TH2_k127_3345901_40 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000002196 212.0
TH2_k127_3345901_41 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000004353 194.0
TH2_k127_3345901_42 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000001053 190.0
TH2_k127_3345901_43 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000002318 181.0
TH2_k127_3345901_44 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.000000000000000000000000000000000000000000000002004 177.0
TH2_k127_3345901_45 DsbA oxidoreductase - - - 0.000000000000000000000000000000000000000000000002487 179.0
TH2_k127_3345901_46 Glyoxalase-like domain K01759,K08234 - 4.4.1.5 0.00000000000000000000000000000000000000000000494 166.0
TH2_k127_3345901_47 Domain of unknown function (DUF4392) - - - 0.00000000000000000000000000000000000005898 156.0
TH2_k127_3345901_48 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000003777 146.0
TH2_k127_3345901_49 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000001023 139.0
TH2_k127_3345901_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 526.0
TH2_k127_3345901_50 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000005361 130.0
TH2_k127_3345901_51 - - - - 0.0000000000000000000000000000004103 126.0
TH2_k127_3345901_52 Histidine kinase K17292 - - 0.000000000000000000000000000009107 128.0
TH2_k127_3345901_53 protein with a C-terminal OMP (outer membrane protein) domain - - - 0.0000000000000000000000006542 116.0
TH2_k127_3345901_54 - - - - 0.000000000000000000002511 96.0
TH2_k127_3345901_55 - - - - 0.0000000000000000007131 100.0
TH2_k127_3345901_56 Protein-tyrosine phosphatase K14165 - 3.1.3.16,3.1.3.48 0.00000000000000000321 90.0
TH2_k127_3345901_57 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000001019 63.0
TH2_k127_3345901_58 PIN domain - - - 0.0000007428 58.0
TH2_k127_3345901_59 Transposase - - - 0.000005866 54.0
TH2_k127_3345901_6 Metallo-beta-lactamase domain protein K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 517.0
TH2_k127_3345901_60 Helix-turn-helix domain - - - 0.00001992 49.0
TH2_k127_3345901_61 Sodium:alanine symporter family K03310 - - 0.00004522 49.0
TH2_k127_3345901_62 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0001109 46.0
TH2_k127_3345901_7 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 506.0
TH2_k127_3345901_8 PFAM cyclase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 463.0
TH2_k127_3345901_9 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 467.0
TH2_k127_3386157_0 Penicillin K01434 - 3.5.1.11 1.1e-293 923.0
TH2_k127_3386157_1 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 314.0
TH2_k127_34196_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.344e-220 705.0
TH2_k127_34196_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 301.0
TH2_k127_34196_2 Polysulphide reductase, NrfD - - - 0.000000000003611 77.0
TH2_k127_34196_3 4Fe-4S ferredoxin K00184 - - 0.0001422 45.0
TH2_k127_3425403_0 DNA photolyase activity K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002901 284.0
TH2_k127_3425403_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001642 281.0
TH2_k127_3425403_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002618 256.0
TH2_k127_3425403_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000006967 240.0
TH2_k127_3425403_4 COG0559 Branched-chain amino acid ABC-type transport system, permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000002379 235.0
TH2_k127_3425403_5 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000283 138.0
TH2_k127_3425403_6 Transposase IS200 like - - - 0.00000000000000000000000000009347 121.0
TH2_k127_3447123_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1040.0
TH2_k127_3447123_1 Heat shock 70 kDa protein K04043 - - 1.755e-311 964.0
TH2_k127_3447123_10 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000005546 194.0
TH2_k127_3447123_11 MarC family integral membrane protein - - - 0.000000000000000000000000000000000000000000000005114 179.0
TH2_k127_3447123_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000004326 173.0
TH2_k127_3447123_13 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000002647 168.0
TH2_k127_3447123_14 GrpE K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000001154 152.0
TH2_k127_3447123_15 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000004654 141.0
TH2_k127_3447123_16 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000006097 50.0
TH2_k127_3447123_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 588.0
TH2_k127_3447123_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 375.0
TH2_k127_3447123_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 346.0
TH2_k127_3447123_5 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 328.0
TH2_k127_3447123_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 316.0
TH2_k127_3447123_7 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005886 256.0
TH2_k127_3447123_8 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004562 243.0
TH2_k127_3447123_9 TIGRFAM maf protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000003839 213.0
TH2_k127_344774_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.118e-262 821.0
TH2_k127_344774_1 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 514.0
TH2_k127_344774_10 PFAM Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 303.0
TH2_k127_344774_11 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000000000000000000006826 147.0
TH2_k127_344774_12 KduI/IolB family K03337 - 5.3.1.30 0.0000000000000000000000004451 117.0
TH2_k127_344774_13 COG1082 Sugar phosphate - - - 0.00000002613 56.0
TH2_k127_344774_2 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 449.0
TH2_k127_344774_3 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 456.0
TH2_k127_344774_4 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 413.0
TH2_k127_344774_5 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 413.0
TH2_k127_344774_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 408.0
TH2_k127_344774_7 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 402.0
TH2_k127_344774_8 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 368.0
TH2_k127_344774_9 tagaturonate epimerase K21619 - 5.1.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 350.0
TH2_k127_3459956_1 TIR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000656 246.0
TH2_k127_3459956_2 cytolysis by virus of host cell K01185,K03791 - 3.2.1.17 0.0000000000000000000000000000000000000000000000000000000093 205.0
TH2_k127_3459956_3 Protein of unknown function (DUF3467) - - - 0.000000000000000000000000000003804 121.0
TH2_k127_3459956_4 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000007601 102.0
TH2_k127_3459956_5 Phage tail sheath C-terminal domain K06907 - - 0.00000000000006589 71.0
TH2_k127_3461447_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1341.0
TH2_k127_3461447_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 3.543e-195 624.0
TH2_k127_3461447_10 glycosyl transferase group 1 K00786,K12994 - 2.4.1.349 0.00000000000000000000000000000000000000000000000000000000000000000000009783 254.0
TH2_k127_3461447_11 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000001451 239.0
TH2_k127_3461447_12 O-methyltransferase activity K05303 - - 0.000000000000000000000000000000000000000000000000000000000000000002016 236.0
TH2_k127_3461447_13 dextransucrase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002158 236.0
TH2_k127_3461447_14 Belongs to the glycosyl hydrolase 32 family - - - 0.0000000000000000000000000000000000000000000000000000000000003538 235.0
TH2_k127_3461447_15 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000000000000000000003753 209.0
TH2_k127_3461447_16 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000004881 216.0
TH2_k127_3461447_17 macromolecule localization K09690 - - 0.00000000000000000000000000000000000000000000000000000002493 206.0
TH2_k127_3461447_18 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000004374 209.0
TH2_k127_3461447_19 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000009327 202.0
TH2_k127_3461447_2 Transposase K07484,K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 609.0
TH2_k127_3461447_20 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000002326 180.0
TH2_k127_3461447_21 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000003433 176.0
TH2_k127_3461447_22 methyltransferase K06983,K15984 - 2.1.1.242 0.0000000000000000000000000000003707 132.0
TH2_k127_3461447_23 Methyltransferase domain - - - 0.0000000000000000000000000000008822 130.0
TH2_k127_3461447_24 pilus assembly protein PilW K02459 - - 0.00000000000000000000828 102.0
TH2_k127_3461447_25 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.00000000000000002728 96.0
TH2_k127_3461447_26 type IV pilus modification protein PilV K02458 - - 0.0000000000000322 78.0
TH2_k127_3461447_27 fimbrial assembly K02461 - - 0.0000000001204 74.0
TH2_k127_3461447_28 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.000000007657 64.0
TH2_k127_3461447_29 General secretion pathway protein H K02457 - - 0.0000001125 60.0
TH2_k127_3461447_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 510.0
TH2_k127_3461447_31 Belongs to the glycosyl hydrolase 32 family - - - 0.000009275 52.0
TH2_k127_3461447_33 - - - - 0.0006305 51.0
TH2_k127_3461447_4 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 473.0
TH2_k127_3461447_5 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 461.0
TH2_k127_3461447_6 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 441.0
TH2_k127_3461447_7 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 422.0
TH2_k127_3461447_8 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 381.0
TH2_k127_3461447_9 Glycosyltransferase like family 2 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001327 258.0
TH2_k127_3477858_0 methyltransferase activity K00574,K12240,K18534,K19620,K20444 - 2.1.1.295,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 523.0
TH2_k127_3477858_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 510.0
TH2_k127_3477858_2 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 330.0
TH2_k127_3477858_3 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002173 281.0
TH2_k127_3477858_4 Fe-S-cluster-containing hydrogenase K08358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004873 257.0
TH2_k127_3477858_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001057 248.0
TH2_k127_3477858_6 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000001311 193.0
TH2_k127_3477858_7 PFAM GAF domain - - - 0.000000000000000000000000000000000000000000005278 169.0
TH2_k127_3477858_8 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000005548 167.0
TH2_k127_3477858_9 heme-binding sites - - - 0.00000000004335 75.0
TH2_k127_348087_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 454.0
TH2_k127_348087_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 364.0
TH2_k127_348087_2 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 358.0
TH2_k127_348087_3 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000000000000000000000001853 143.0
TH2_k127_348087_5 PFAM Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000003239 111.0
TH2_k127_348087_6 Phospholipid methyltransferase - - - 0.00000000000000004906 91.0
TH2_k127_348087_7 - - - - 0.0000003612 54.0
TH2_k127_3488849_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 378.0
TH2_k127_3488849_1 eight transmembrane protein EpsH - - - 0.000000000000000000000000000000000000000001474 167.0
TH2_k127_3488849_2 PFAM S23 ribosomal protein - - - 0.000000000000000000000000003081 114.0
TH2_k127_3488849_3 Sigma-54 factor interaction domain-containing protein K02481 - - 0.000000000000000000002239 97.0
TH2_k127_3488849_4 nuclease activity - - - 0.000000000000003996 81.0
TH2_k127_3488849_5 Bacterial antitoxin of type II TA system, VapB - - - 0.000002107 52.0
TH2_k127_3531090_0 peptide catabolic process - - - 0.00000000000000000000000000000000000000000000000003069 190.0
TH2_k127_3531090_1 Amidohydrolase - - - 0.0000000000000000000000000001256 124.0
TH2_k127_3533297_0 PFAM alpha beta hydrolase fold K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000002726 261.0
TH2_k127_3533297_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000007906 135.0
TH2_k127_3533297_2 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000009691 130.0
TH2_k127_3533297_3 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000000000008447 106.0
TH2_k127_3533297_4 Heavy-metal-associated domain K07213 - - 0.00000000003825 64.0
TH2_k127_3533297_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000001979 62.0
TH2_k127_3547820_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1106.0
TH2_k127_3547820_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 5.069e-219 685.0
TH2_k127_3547820_10 Belongs to the bacterial solute-binding protein 3 family K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 332.0
TH2_k127_3547820_11 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 298.0
TH2_k127_3547820_12 Enoyl-CoA hydratase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001377 276.0
TH2_k127_3547820_13 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007686 270.0
TH2_k127_3547820_14 radical SAM domain protein K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002005 264.0
TH2_k127_3547820_15 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001277 241.0
TH2_k127_3547820_16 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000007729 236.0
TH2_k127_3547820_17 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001583 230.0
TH2_k127_3547820_18 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000001298 229.0
TH2_k127_3547820_19 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000002785 239.0
TH2_k127_3547820_2 Enoyl-CoA hydratase/isomerase K07539 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 4.069e-217 677.0
TH2_k127_3547820_20 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000001356 186.0
TH2_k127_3547820_21 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000004964 177.0
TH2_k127_3547820_22 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000000000001904 175.0
TH2_k127_3547820_23 Vacuole effluxer Atg22 like - - - 0.000000000000000000000000000000000000000000001819 180.0
TH2_k127_3547820_24 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000001048 144.0
TH2_k127_3547820_25 pfam abc K01995 - - 0.0000000000000000000000000000000000005616 147.0
TH2_k127_3547820_26 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000001698 143.0
TH2_k127_3547820_27 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000001347 127.0
TH2_k127_3547820_28 Glycine cleavage H-protein - - - 0.00000000000000000000000006747 108.0
TH2_k127_3547820_29 Predicted Permease Membrane Region K07085 - - 0.0000000000000000000002054 98.0
TH2_k127_3547820_3 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 584.0
TH2_k127_3547820_30 Formate-dependent nitrite reductase, membrane - - - 0.0000000000000000000004554 108.0
TH2_k127_3547820_31 Tyrosine phosphatase family - - - 0.0000000008194 69.0
TH2_k127_3547820_32 ThiS family K03636 - - 0.000000001394 62.0
TH2_k127_3547820_33 Transporter - - - 0.000000313 56.0
TH2_k127_3547820_34 4 iron, 4 sulfur cluster binding - - - 0.0000009362 59.0
TH2_k127_3547820_4 PFAM Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 579.0
TH2_k127_3547820_5 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 501.0
TH2_k127_3547820_6 Dehydrogenase K00030,K07246 - 1.1.1.41,1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 388.0
TH2_k127_3547820_7 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 367.0
TH2_k127_3547820_8 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 344.0
TH2_k127_3547820_9 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 345.0
TH2_k127_3550045_0 Protein involved in outer membrane biogenesis - - - 9.849e-294 941.0
TH2_k127_3550045_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 581.0
TH2_k127_3550045_2 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 461.0
TH2_k127_3550045_3 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 410.0
TH2_k127_3550045_4 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000002235 220.0
TH2_k127_3550045_5 Poly A polymerase head domain K00970 - 2.7.7.19 0.000009652 51.0
TH2_k127_3553781_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 3.478e-304 955.0
TH2_k127_3553781_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 515.0
TH2_k127_3553781_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 496.0
TH2_k127_3553781_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000006416 204.0
TH2_k127_3553781_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000006489 180.0
TH2_k127_3553781_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000001334 146.0
TH2_k127_3561340_0 acyl-CoA dehydrogenase - - - 1.984e-204 651.0
TH2_k127_3561340_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 544.0
TH2_k127_3561340_2 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 425.0
TH2_k127_3561340_3 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 331.0
TH2_k127_3561340_4 phosphonoacetaldehyde hydrolase activity K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000002063 194.0
TH2_k127_3561340_5 Secondary thiamine-phosphate synthase enzyme - - - 0.000000000000000000000000000000000000000000000000007846 183.0
TH2_k127_3561340_6 SMART serine threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase K01090 - 3.1.3.16 0.00000000000000000000003037 109.0
TH2_k127_3561340_7 - - - - 0.000000000000000003198 99.0
TH2_k127_3561340_8 phosphorelay signal transduction system K03413,K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.0007487 45.0
TH2_k127_36062_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001268 288.0
TH2_k127_36062_1 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000185 214.0
TH2_k127_36062_2 PFAM nitroreductase - - - 0.00000000000000000000000000000000000000000000003354 181.0
TH2_k127_36062_3 Cupin 2, conserved barrel domain protein - - - 0.000002675 49.0
TH2_k127_36062_4 transferase activity, transferring glycosyl groups - - - 0.0009687 42.0
TH2_k127_3612146_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 323.0
TH2_k127_3612146_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000007745 126.0
TH2_k127_3666354_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1047.0
TH2_k127_3666354_1 Belongs to the transketolase family K00615 - 2.2.1.1 1.026e-294 918.0
TH2_k127_3666354_10 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 436.0
TH2_k127_3666354_11 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 392.0
TH2_k127_3666354_12 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 385.0
TH2_k127_3666354_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 377.0
TH2_k127_3666354_14 Domain of unknown function (DUF4922) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 387.0
TH2_k127_3666354_15 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 374.0
TH2_k127_3666354_16 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 375.0
TH2_k127_3666354_17 binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 299.0
TH2_k127_3666354_18 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003651 282.0
TH2_k127_3666354_19 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002847 262.0
TH2_k127_3666354_2 glucan 1,4-alpha-glucosidase activity - - - 4.081e-250 788.0
TH2_k127_3666354_20 EcsC protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003506 256.0
TH2_k127_3666354_21 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000003081 245.0
TH2_k127_3666354_22 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000003927 243.0
TH2_k127_3666354_23 Protein of unknown function (DUF1460) - - - 0.00000000000000000000000000000000000000000000000000000000000000006574 231.0
TH2_k127_3666354_24 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000756 222.0
TH2_k127_3666354_25 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000004046 194.0
TH2_k127_3666354_26 Involved in chromosome partitioning - - - 0.0000000000000000000000000000000000000000000002583 177.0
TH2_k127_3666354_27 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000008415 156.0
TH2_k127_3666354_28 acetyltransferase K22441 - 2.3.1.57 0.0000000000000000000000000000000000000002662 167.0
TH2_k127_3666354_29 - - - - 0.0000000000000000000000000000000000103 138.0
TH2_k127_3666354_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 8.455e-202 635.0
TH2_k127_3666354_30 Universal stress protein - - - 0.000000000000000000000000000002293 128.0
TH2_k127_3666354_31 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000008307 117.0
TH2_k127_3666354_32 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.000000000000000000000000001502 114.0
TH2_k127_3666354_33 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.0000000000000005903 78.0
TH2_k127_3666354_34 Protein of unknown function (DUF2769) - - - 0.0000000000003817 71.0
TH2_k127_3666354_35 - - - - 0.00000004526 54.0
TH2_k127_3666354_36 Glucokinase K00845 - 2.7.1.2 0.0000003307 54.0
TH2_k127_3666354_37 - - - - 0.0000707 51.0
TH2_k127_3666354_4 Glycosyltransferase like family 2 - - - 1.991e-199 633.0
TH2_k127_3666354_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.361e-196 621.0
TH2_k127_3666354_6 Major facilitator Superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 610.0
TH2_k127_3666354_7 Stage II sporulation protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 595.0
TH2_k127_3666354_8 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 507.0
TH2_k127_3666354_9 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 452.0
TH2_k127_3666421_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535 - 3.6.3.6 3.842e-223 704.0
TH2_k127_3666421_1 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 584.0
TH2_k127_3666421_2 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 357.0
TH2_k127_3666421_3 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 330.0
TH2_k127_3666421_4 Amino acid permease - - - 0.00000000007725 64.0
TH2_k127_3669186_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.303e-271 852.0
TH2_k127_3669186_1 Domain of unknown function (DUF1846) - - - 1.203e-253 790.0
TH2_k127_3669186_10 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 499.0
TH2_k127_3669186_11 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 460.0
TH2_k127_3669186_12 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 449.0
TH2_k127_3669186_13 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 408.0
TH2_k127_3669186_14 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 394.0
TH2_k127_3669186_15 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 362.0
TH2_k127_3669186_16 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 348.0
TH2_k127_3669186_17 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 335.0
TH2_k127_3669186_18 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 324.0
TH2_k127_3669186_19 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 300.0
TH2_k127_3669186_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.216e-253 792.0
TH2_k127_3669186_20 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000012 295.0
TH2_k127_3669186_21 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003539 250.0
TH2_k127_3669186_22 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000002058 205.0
TH2_k127_3669186_23 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000009735 186.0
TH2_k127_3669186_24 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000003854 162.0
TH2_k127_3669186_25 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000001268 147.0
TH2_k127_3669186_26 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000003692 153.0
TH2_k127_3669186_27 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000001429 148.0
TH2_k127_3669186_28 AsmA-like C-terminal region K07289 - - 0.00000000000000000000000000000000001652 153.0
TH2_k127_3669186_29 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000003219 141.0
TH2_k127_3669186_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 602.0
TH2_k127_3669186_30 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - 0.0000000000000000000000000000001678 131.0
TH2_k127_3669186_31 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000000000000002643 121.0
TH2_k127_3669186_32 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000008677 104.0
TH2_k127_3669186_33 Lipopolysaccharide-assembly, LptC-related - - - 0.000000000000003614 83.0
TH2_k127_3669186_34 PhoQ Sensor - - - 0.0000006496 60.0
TH2_k127_3669186_35 Protein of unknown function (DUF1059) - - - 0.000019 51.0
TH2_k127_3669186_4 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 610.0
TH2_k127_3669186_5 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 593.0
TH2_k127_3669186_6 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 587.0
TH2_k127_3669186_7 Predicted ATPase of the ABC class - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 584.0
TH2_k127_3669186_8 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 518.0
TH2_k127_3669186_9 amino acid-binding ACT domain protein K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 506.0
TH2_k127_3676553_0 CoA-binding domain protein K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 437.0
TH2_k127_3676553_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 405.0
TH2_k127_3676553_2 binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 379.0
TH2_k127_3676553_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 347.0
TH2_k127_3676553_4 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004674 269.0
TH2_k127_3676553_5 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001592 277.0
TH2_k127_3676553_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007798 274.0
TH2_k127_3676553_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000002889 75.0
TH2_k127_3676553_8 Serine hydrolase involved in the detoxification of formaldehyde K03930,K17076 - - 0.0000001084 64.0
TH2_k127_3676553_9 - - - - 0.0000005753 52.0
TH2_k127_3687167_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 572.0
TH2_k127_3687167_1 Zn-dependent hydrolase, glyoxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 411.0
TH2_k127_3687167_10 Staphylococcal nuclease homologue K01174 - 3.1.31.1 0.000000000000003135 78.0
TH2_k127_3687167_11 endonuclease activity - - - 0.0000000001567 65.0
TH2_k127_3687167_12 - - - - 0.000000001946 61.0
TH2_k127_3687167_13 Domain of unknown function (DUF362) - - - 0.00001443 53.0
TH2_k127_3687167_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 363.0
TH2_k127_3687167_3 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 340.0
TH2_k127_3687167_4 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000006753 212.0
TH2_k127_3687167_5 PFAM Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000001866 140.0
TH2_k127_3687167_6 AraC-like ligand binding domain - - - 0.0000000000000000000000000007976 116.0
TH2_k127_3687167_7 Yip1 domain - - - 0.00000000000000000000000001665 122.0
TH2_k127_3689116_0 S1, RNA binding domain K06959 - - 0.0 1090.0
TH2_k127_3689116_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1006.0
TH2_k127_3689116_10 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 295.0
TH2_k127_3689116_11 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000001129 256.0
TH2_k127_3689116_12 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003307 250.0
TH2_k127_3689116_13 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000002078 230.0
TH2_k127_3689116_14 Pfam:TPM K08988 - - 0.00000000000000000000000000000000000000000000000000000000000003756 221.0
TH2_k127_3689116_15 PFAM molybdopterin oxidoreductase Fe4S4 region - - - 0.00000000000000000000000000000000000000000000000000009007 188.0
TH2_k127_3689116_16 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000001337 163.0
TH2_k127_3689116_17 PFAM methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000004504 164.0
TH2_k127_3689116_18 FecR protein - - - 0.000000000000000000000000000000000002986 143.0
TH2_k127_3689116_19 Belongs to the ompA family - - - 0.0000000000000000000000000000000001782 141.0
TH2_k127_3689116_2 PFAM Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 3.792e-250 785.0
TH2_k127_3689116_20 - - - - 0.0000000000000000000000000008058 117.0
TH2_k127_3689116_21 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.0000000000000000000001103 104.0
TH2_k127_3689116_22 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000003841 97.0
TH2_k127_3689116_23 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000003468 100.0
TH2_k127_3689116_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.19e-209 664.0
TH2_k127_3689116_4 Elongator protein 3, MiaB family, Radical SAM - - - 2.677e-208 659.0
TH2_k127_3689116_5 PFAM CHASE2 domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 545.0
TH2_k127_3689116_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 469.0
TH2_k127_3689116_7 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 402.0
TH2_k127_3689116_8 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 317.0
TH2_k127_3689116_9 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 295.0
TH2_k127_3732164_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 7.16e-259 808.0
TH2_k127_3732164_1 Belongs to the enoyl-CoA hydratase isomerase family K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 9.664e-202 639.0
TH2_k127_3732164_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00009822 47.0
TH2_k127_3732164_2 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 501.0
TH2_k127_3732164_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 472.0
TH2_k127_3732164_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 427.0
TH2_k127_3732164_5 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 355.0
TH2_k127_3732164_6 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 328.0
TH2_k127_3732164_7 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 311.0
TH2_k127_3732164_8 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 311.0
TH2_k127_3732164_9 PFAM ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 293.0
TH2_k127_384094_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1470.0
TH2_k127_384094_1 Protein of unknown function (DUF1214) - - - 2.318e-227 714.0
TH2_k127_384094_10 PFAM Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000001019 100.0
TH2_k127_384094_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.435e-216 677.0
TH2_k127_384094_3 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 490.0
TH2_k127_384094_4 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 296.0
TH2_k127_384094_5 Deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000001337 236.0
TH2_k127_384094_6 GXGXG motif - - - 0.00000000000000000000000000000000000000000000000000000000000009169 246.0
TH2_k127_384094_7 Glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000001368 233.0
TH2_k127_384094_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000562 178.0
TH2_k127_384094_9 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000001216 186.0
TH2_k127_386160_0 AMP-binding enzyme K01897 - 6.2.1.3 3.854e-277 864.0
TH2_k127_386160_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 600.0
TH2_k127_386160_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 375.0
TH2_k127_386160_11 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 369.0
TH2_k127_386160_12 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 378.0
TH2_k127_386160_13 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 368.0
TH2_k127_386160_14 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 359.0
TH2_k127_386160_15 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000002519 261.0
TH2_k127_386160_16 Fumarylacetoacetate (FAA) hydrolase K01826 - 5.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000002289 258.0
TH2_k127_386160_17 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001901 250.0
TH2_k127_386160_18 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001278 228.0
TH2_k127_386160_19 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000002066 135.0
TH2_k127_386160_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 518.0
TH2_k127_386160_20 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000001385 109.0
TH2_k127_386160_21 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000004837 100.0
TH2_k127_386160_22 - - - - 0.000001364 57.0
TH2_k127_386160_3 Beta-ketoacyl synthase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 485.0
TH2_k127_386160_4 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 444.0
TH2_k127_386160_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 441.0
TH2_k127_386160_6 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 439.0
TH2_k127_386160_7 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 445.0
TH2_k127_386160_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 426.0
TH2_k127_386160_9 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 393.0
TH2_k127_3863960_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.121e-223 702.0
TH2_k127_3863960_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 514.0
TH2_k127_3863960_2 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 340.0
TH2_k127_3863960_3 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001533 289.0
TH2_k127_3863960_4 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003222 276.0
TH2_k127_3863960_5 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 269.0
TH2_k127_3863960_6 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000000000001145 173.0
TH2_k127_3863960_7 Polymer-forming cytoskeletal - - - 0.00000000000000000000007794 104.0
TH2_k127_3863960_8 - - - - 0.000000000000000000007134 99.0
TH2_k127_3946798_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 2.685e-202 632.0
TH2_k127_3946798_1 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 332.0
TH2_k127_3946798_2 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 305.0
TH2_k127_3946798_3 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001284 267.0
TH2_k127_3946798_4 including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005616 269.0
TH2_k127_3946798_5 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007414 270.0
TH2_k127_3946798_6 - - - - 0.000000000000000000000000000000000000000000000000000000002726 207.0
TH2_k127_3946798_7 THIoesterase K18700 - 3.1.2.29 0.00000000000000000000000003573 112.0
TH2_k127_3946798_8 Ferric uptake regulator family K09825 - - 0.00000000000000000000002306 105.0
TH2_k127_3946798_9 Catalase K03781 - 1.11.1.6 0.00000000000001192 74.0
TH2_k127_3967190_0 3-beta hydroxysteroid dehydrogenase/isomerase family K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 382.0
TH2_k127_3967190_1 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 382.0
TH2_k127_3995466_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 523.0
TH2_k127_3995466_1 FAD linked oxidase domain protein K00803,K11472 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 307.0
TH2_k127_3995466_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 290.0
TH2_k127_3995466_3 Cytochrome C biogenesis protein - - - 0.00000000000000000000000000000000000000000000000605 190.0
TH2_k127_3995466_4 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000004481 156.0
TH2_k127_3995466_5 Universal stress protein - - - 0.000000000000000000000001568 109.0
TH2_k127_3995466_6 - - - - 0.00000003724 63.0
TH2_k127_3995466_7 Redoxin - - - 0.0000007346 55.0
TH2_k127_3995466_8 Thioredoxin-like - - - 0.000001623 52.0
TH2_k127_4033547_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 5.903e-212 672.0
TH2_k127_4033547_1 PFAM Aminotransferase class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 391.0
TH2_k127_4033547_2 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000002864 226.0
TH2_k127_4081647_0 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 505.0
TH2_k127_4081647_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 449.0
TH2_k127_4081647_10 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000005027 135.0
TH2_k127_4081647_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000009532 141.0
TH2_k127_4081647_12 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000001618 124.0
TH2_k127_4081647_13 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000002217 130.0
TH2_k127_4081647_14 PFAM Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000007712 106.0
TH2_k127_4081647_15 polysaccharide biosynthetic process - - - 0.00000000000000000002538 104.0
TH2_k127_4081647_16 Methionine biosynthesis protein MetW - - - 0.000000000000004177 83.0
TH2_k127_4081647_17 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000005231 78.0
TH2_k127_4081647_18 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000007313 73.0
TH2_k127_4081647_19 PFAM Glycosyl transferase family 2 - - - 0.0000000005537 70.0
TH2_k127_4081647_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 415.0
TH2_k127_4081647_20 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.1.163,2.1.1.201 0.0000000555 63.0
TH2_k127_4081647_21 - - - - 0.0000001387 64.0
TH2_k127_4081647_3 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 401.0
TH2_k127_4081647_4 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 399.0
TH2_k127_4081647_5 glycosyl transferase family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 320.0
TH2_k127_4081647_6 WbqC-like protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001387 257.0
TH2_k127_4081647_7 Domain of unknown function (DUF3473) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002598 258.0
TH2_k127_4081647_8 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000001184 195.0
TH2_k127_4081647_9 Glycosyltransferase 28 domain - - - 0.0000000000000000000000000000000005018 137.0
TH2_k127_4104064_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1098.0
TH2_k127_4104064_1 ABC transporter transmembrane region K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 578.0
TH2_k127_4104064_2 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000004863 197.0
TH2_k127_4104064_3 exodeoxyribonuclease I activity - - - 0.0000000000000116 76.0
TH2_k127_4139441_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 472.0
TH2_k127_4139441_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 381.0
TH2_k127_4139441_2 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 382.0
TH2_k127_4139441_3 Organic solvent tolerance protein K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 340.0
TH2_k127_4139441_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005626 279.0
TH2_k127_4139441_5 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000008481 239.0
TH2_k127_4147414_0 Beta-eliminating lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 332.0
TH2_k127_4147414_1 transferase activity, transferring glycosyl groups K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 322.0
TH2_k127_4147414_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 296.0
TH2_k127_4147414_3 glycosyl transferase family 39 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 301.0
TH2_k127_4147414_4 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008634 273.0
TH2_k127_4147414_5 Oxidoreductase family, NAD-binding Rossmann fold K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000001174 178.0
TH2_k127_4147414_6 Lipid A Biosynthesis N-terminal domain - - - 0.0000000000000000000000000000003355 126.0
TH2_k127_4147414_7 sam-dependent methyltransferase - - - 0.000000000000001159 86.0
TH2_k127_4147414_8 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00000000000001269 85.0
TH2_k127_4147414_9 dehydrogenases and related proteins - - - 0.00000000002449 74.0
TH2_k127_4148429_0 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 298.0
TH2_k127_4148429_1 Virulence factor BrkB K07058 - - 0.0000000000000000000000000004272 124.0
TH2_k127_416999_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 493.0
TH2_k127_416999_1 PFAM Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 302.0
TH2_k127_416999_10 PDGLE domain K02009 - - 0.000000000000000009045 95.0
TH2_k127_416999_11 Putative MetA-pathway of phenol degradation - - - 0.0002283 53.0
TH2_k127_416999_2 ABC transporter K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 294.0
TH2_k127_416999_3 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002954 279.0
TH2_k127_416999_4 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000003541 252.0
TH2_k127_416999_5 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000367 224.0
TH2_k127_416999_6 Domain of unknown function (DUF3842) - - - 0.000000000000000000000000000000000000000000004229 168.0
TH2_k127_416999_7 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000000000000004239 142.0
TH2_k127_416999_8 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000008204 147.0
TH2_k127_416999_9 Predicted RNA-binding protein - - - 0.0000000000000000007824 88.0
TH2_k127_4195248_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 427.0
TH2_k127_4195248_1 Beta-ketoacyl synthase, N-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 345.0
TH2_k127_4195248_10 Dehydratase - - - 0.00000144 57.0
TH2_k127_4195248_11 lysine biosynthetic process via aminoadipic acid K00997,K06133 - 2.7.8.7 0.000001836 58.0
TH2_k127_4195248_2 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 295.0
TH2_k127_4195248_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001528 272.0
TH2_k127_4195248_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000006081 162.0
TH2_k127_4195248_5 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000001295 145.0
TH2_k127_4195248_6 Outer membrane lipoprotein carrier protein LolA - - - 0.0000000000000000000000003347 113.0
TH2_k127_4195248_7 Acyl-transferase - - - 0.000000000000000002539 95.0
TH2_k127_4195248_8 - - - - 0.0000000000001597 79.0
TH2_k127_4204845_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.464e-246 771.0
TH2_k127_4204845_1 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 330.0
TH2_k127_4204845_2 SnoaL-like domain - - - 0.00000000000000000000000000000001463 132.0
TH2_k127_4204845_3 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000009793 89.0
TH2_k127_4206982_0 phosphoribosyltransferase. Source PGD - - - 1.103e-207 657.0
TH2_k127_4206982_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 560.0
TH2_k127_4206982_10 Belongs to the phosphoglycerate mutase family K22305 - 3.1.3.3 0.00000000000000000000000000000000000000000004587 168.0
TH2_k127_4206982_11 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000006227 160.0
TH2_k127_4206982_12 sterol carrier protein - - - 0.000000000000000000000008842 104.0
TH2_k127_4206982_13 GUN4-like - - - 0.0000000000000000004505 90.0
TH2_k127_4206982_14 HD domain K07814 - - 0.000000000000000003572 91.0
TH2_k127_4206982_15 - - - - 0.0000000002304 68.0
TH2_k127_4206982_16 alpha beta - - - 0.0000000006291 61.0
TH2_k127_4206982_17 Psort location Cytoplasmic, score - - - 0.000000983 56.0
TH2_k127_4206982_19 Mo-molybdopterin cofactor metabolic process - - - 0.00001179 52.0
TH2_k127_4206982_2 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 386.0
TH2_k127_4206982_3 tagaturonate epimerase K21619 - 5.1.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 355.0
TH2_k127_4206982_4 Pyridoxal-phosphate dependent enzyme K01505,K05396,K19105 - 3.5.99.7,4.4.1.15,5.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002958 289.0
TH2_k127_4206982_5 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000261 291.0
TH2_k127_4206982_6 COG1082 Sugar phosphate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001462 251.0
TH2_k127_4206982_7 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000001724 250.0
TH2_k127_4206982_8 PFAM formylmethanofuran dehydrogenase subunit E region K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000003656 211.0
TH2_k127_4225598_0 PFAM Pyruvate carboxyltransferase - - - 1.44e-283 881.0
TH2_k127_4225598_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.933e-243 763.0
TH2_k127_4225598_10 RHS Repeat - - - 0.00000000000000000000000000000000000000000006741 168.0
TH2_k127_4225598_11 self proteolysis - - - 0.00000000000000000000000000005715 136.0
TH2_k127_4225598_12 RHS Repeat - - - 0.000000000000000000509 88.0
TH2_k127_4225598_14 - - - - 0.0001613 52.0
TH2_k127_4225598_15 cheY-homologous receiver domain - - - 0.0002045 50.0
TH2_k127_4225598_2 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 514.0
TH2_k127_4225598_3 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 447.0
TH2_k127_4225598_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 443.0
TH2_k127_4225598_5 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 384.0
TH2_k127_4225598_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009723 286.0
TH2_k127_4225598_7 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000713 263.0
TH2_k127_4225598_8 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003147 249.0
TH2_k127_4225598_9 COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.0000000000000000000000000000000000000000000000004133 189.0
TH2_k127_4232560_0 Large extracellular alpha-helical protein K06894 - - 0.0 1311.0
TH2_k127_4232560_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 5.204e-200 642.0
TH2_k127_4232560_10 B12 binding domain K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 501.0
TH2_k127_4232560_11 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 478.0
TH2_k127_4232560_12 DNA helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 499.0
TH2_k127_4232560_13 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 465.0
TH2_k127_4232560_14 Thiamine-phosphate synthase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 441.0
TH2_k127_4232560_15 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 428.0
TH2_k127_4232560_16 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006891 427.0
TH2_k127_4232560_17 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 408.0
TH2_k127_4232560_18 ATPase BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 389.0
TH2_k127_4232560_19 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 392.0
TH2_k127_4232560_2 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 4.777e-198 622.0
TH2_k127_4232560_20 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 388.0
TH2_k127_4232560_21 Thi4 family K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 358.0
TH2_k127_4232560_22 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 354.0
TH2_k127_4232560_23 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 343.0
TH2_k127_4232560_24 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 339.0
TH2_k127_4232560_25 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 346.0
TH2_k127_4232560_26 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 320.0
TH2_k127_4232560_27 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 320.0
TH2_k127_4232560_28 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 328.0
TH2_k127_4232560_29 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 324.0
TH2_k127_4232560_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 608.0
TH2_k127_4232560_30 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 297.0
TH2_k127_4232560_31 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 292.0
TH2_k127_4232560_32 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 291.0
TH2_k127_4232560_33 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000447 282.0
TH2_k127_4232560_34 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000382 274.0
TH2_k127_4232560_35 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007772 267.0
TH2_k127_4232560_36 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000209 263.0
TH2_k127_4232560_37 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001391 263.0
TH2_k127_4232560_38 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005732 253.0
TH2_k127_4232560_39 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001312 251.0
TH2_k127_4232560_4 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 606.0
TH2_k127_4232560_40 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001941 244.0
TH2_k127_4232560_41 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000002647 233.0
TH2_k127_4232560_42 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.0000000000000000000000000000000000000000000000000000000000000000673 233.0
TH2_k127_4232560_43 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000274 233.0
TH2_k127_4232560_44 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000001356 228.0
TH2_k127_4232560_45 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000003026 226.0
TH2_k127_4232560_46 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000001783 207.0
TH2_k127_4232560_47 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000207 198.0
TH2_k127_4232560_48 [acyl-carrier-protein] S-malonyltransferase activity - - - 0.0000000000000000000000000000000000003068 153.0
TH2_k127_4232560_49 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000000000004862 150.0
TH2_k127_4232560_5 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 571.0
TH2_k127_4232560_50 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000002292 145.0
TH2_k127_4232560_51 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000004182 138.0
TH2_k127_4232560_52 Universal stress protein K06149 - - 0.000000000000000000000000000000001193 134.0
TH2_k127_4232560_53 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000000000000000003521 129.0
TH2_k127_4232560_54 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000000000000000000000001748 124.0
TH2_k127_4232560_55 Phosphopantetheine attachment site K02078 - - 0.000000000000000000000000000419 115.0
TH2_k127_4232560_56 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000001518 105.0
TH2_k127_4232560_57 23S rRNA-intervening sequence protein - - - 0.00000000000000000002254 95.0
TH2_k127_4232560_58 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.000000000006376 71.0
TH2_k127_4232560_59 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0000000005178 66.0
TH2_k127_4232560_6 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007984 509.0
TH2_k127_4232560_60 D-glucuronyl C5-epimerase C-terminus - - - 0.00002287 56.0
TH2_k127_4232560_7 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 512.0
TH2_k127_4232560_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008939 527.0
TH2_k127_4232560_9 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 504.0
TH2_k127_4243587_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 597.0
TH2_k127_4243587_1 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 318.0
TH2_k127_4243587_2 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000002149 269.0
TH2_k127_4249075_0 von Willebrand factor, type A K07114 - - 6.925e-313 976.0
TH2_k127_4249075_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 410.0
TH2_k127_4255826_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 503.0
TH2_k127_4255826_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 454.0
TH2_k127_4255826_2 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 392.0
TH2_k127_4255826_3 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000001157 252.0
TH2_k127_4255826_4 Ferrochelatase K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000142 249.0
TH2_k127_4255826_5 nitric oxide reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001791 224.0
TH2_k127_4255826_6 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000001082 128.0
TH2_k127_4255826_7 YtxH-like protein - - - 0.0000000000000000000000000001096 117.0
TH2_k127_4255826_8 Smr domain - - - 0.0000000000000000000000004487 107.0
TH2_k127_4255941_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.356e-219 687.0
TH2_k127_4255941_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 437.0
TH2_k127_4255941_2 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 347.0
TH2_k127_4255941_3 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006049 278.0
TH2_k127_4255941_4 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008852 272.0
TH2_k127_4255941_5 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000000006544 213.0
TH2_k127_4255941_6 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000007526 204.0
TH2_k127_4255941_7 Phage integrase family - - - 0.000000000000000000007122 94.0
TH2_k127_4255941_8 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.0000000000001889 77.0
TH2_k127_4265848_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0 1050.0
TH2_k127_4265848_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 578.0
TH2_k127_4265848_10 Putative transposon-encoded protein (DUF2080) - - - 0.00000000000002372 74.0
TH2_k127_4265848_11 Methylamine utilisation protein MauE - - - 0.0000000000005964 75.0
TH2_k127_4265848_12 TIGRFAM C_GCAxxG_C_C family - - - 0.00000006065 59.0
TH2_k127_4265848_13 Putative transposon-encoded protein (DUF2080) - - - 0.000006587 48.0
TH2_k127_4265848_2 Aliphatic nitrilase K01502 - 3.5.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 338.0
TH2_k127_4265848_3 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 321.0
TH2_k127_4265848_4 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 299.0
TH2_k127_4265848_5 PIN domain - - - 0.000000000000000000000000000000000000000000000000000513 189.0
TH2_k127_4265848_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000007853 171.0
TH2_k127_4265848_7 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000006264 139.0
TH2_k127_4265848_8 Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - 0.000000000000000000000000000000002035 133.0
TH2_k127_4269128_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 2.898e-218 701.0
TH2_k127_4269128_1 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 614.0
TH2_k127_4269128_2 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 342.0
TH2_k127_4269128_3 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 331.0
TH2_k127_4269128_4 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001171 279.0
TH2_k127_4269128_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000001755 184.0
TH2_k127_4269128_6 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.000001155 57.0
TH2_k127_4286836_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 6.03e-322 1006.0
TH2_k127_4286836_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 565.0
TH2_k127_4286836_2 in signal transduction K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 476.0
TH2_k127_4286836_3 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000009443 231.0
TH2_k127_4286836_4 4Fe-4S binding domain - - - 0.0000000000000001633 85.0
TH2_k127_4286836_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000002142 68.0
TH2_k127_4287859_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 488.0
TH2_k127_4287859_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 438.0
TH2_k127_4287859_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 432.0
TH2_k127_4287859_3 3-dehydroquinate synthase (EC 4.6.1.3) K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 366.0
TH2_k127_4287859_4 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 355.0
TH2_k127_4287859_5 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 336.0
TH2_k127_4287859_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0003674,GO:0003824,GO:0004764,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0055114,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002288 277.0
TH2_k127_4287859_7 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000001039 199.0
TH2_k127_4287859_8 3-dehydroquinate dehydratase activity K00014,K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000001707 181.0
TH2_k127_4287859_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000001407 151.0
TH2_k127_4365194_0 UDP binding domain K02474,K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 541.0
TH2_k127_4365194_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 436.0
TH2_k127_4365194_2 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 354.0
TH2_k127_4365194_3 8-oxoguanine DNA glycosylase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000005922 216.0
TH2_k127_4365194_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000008374 82.0
TH2_k127_4380653_0 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 414.0
TH2_k127_4380653_1 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 400.0
TH2_k127_4380653_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000246 253.0
TH2_k127_4380653_3 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000001932 85.0
TH2_k127_4380653_4 NfeD-like C-terminal, partner-binding - - - 0.000000000000000996 83.0
TH2_k127_446_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 453.0
TH2_k127_446_1 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 396.0
TH2_k127_446_2 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 391.0
TH2_k127_446_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 307.0
TH2_k127_446_4 peptide catabolic process - - - 0.00000000000000000000000000000000000000000003348 184.0
TH2_k127_446_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000003896 158.0
TH2_k127_446_6 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000001586 148.0
TH2_k127_446_7 Peptidase family M28 - - - 0.0000000000000000000000000000000000006238 161.0
TH2_k127_446_8 - - - - 0.0000000000000005321 84.0
TH2_k127_4461218_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 6.301e-215 677.0
TH2_k127_4461218_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 1.037e-200 638.0
TH2_k127_4461218_10 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 298.0
TH2_k127_4461218_11 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 300.0
TH2_k127_4461218_12 antibiotic catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 305.0
TH2_k127_4461218_13 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 288.0
TH2_k127_4461218_14 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002436 286.0
TH2_k127_4461218_15 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001251 267.0
TH2_k127_4461218_16 Allophanate hydrolase subunit 1 K06351 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001013 254.0
TH2_k127_4461218_18 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000003865 225.0
TH2_k127_4461218_19 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000608 217.0
TH2_k127_4461218_2 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 447.0
TH2_k127_4461218_20 B3/4 domain - - - 0.000000000000000000000000000000000000000000000000000005599 198.0
TH2_k127_4461218_21 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000000000000000004861 190.0
TH2_k127_4461218_22 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000009361 186.0
TH2_k127_4461218_23 NTPase - - - 0.00000000000000000000000000000000000000000000000004424 184.0
TH2_k127_4461218_24 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000117 187.0
TH2_k127_4461218_25 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000002056 155.0
TH2_k127_4461218_26 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000948 162.0
TH2_k127_4461218_27 - K01507 - 3.6.1.1 0.0000000000000000000000000000002585 126.0
TH2_k127_4461218_28 Membrane - - - 0.0000000000000000000000002263 112.0
TH2_k127_4461218_29 Diguanylate cyclase - - - 0.00000000000000007085 84.0
TH2_k127_4461218_3 COG1363 Cellulase M and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 427.0
TH2_k127_4461218_30 Evidence 4 Homologs of previously reported genes of K03975 - - 0.00000000115 60.0
TH2_k127_4461218_4 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 346.0
TH2_k127_4461218_5 extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 349.0
TH2_k127_4461218_6 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 308.0
TH2_k127_4461218_7 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 327.0
TH2_k127_4461218_8 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 302.0
TH2_k127_4461218_9 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 316.0
TH2_k127_4491635_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.099e-248 780.0
TH2_k127_4491635_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 527.0
TH2_k127_4491635_10 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000007535 208.0
TH2_k127_4491635_11 CHRD domain - - - 0.000000000000000000000000000000000000000000000000000006408 196.0
TH2_k127_4491635_12 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000001228 197.0
TH2_k127_4491635_13 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000003852 180.0
TH2_k127_4491635_15 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000209 145.0
TH2_k127_4491635_16 Thioesterase superfamily K02614 - - 0.000000000000000000000000000004377 125.0
TH2_k127_4491635_17 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000000000001367 127.0
TH2_k127_4491635_18 Probable molybdopterin binding domain - - - 0.00000000000000000000000000159 116.0
TH2_k127_4491635_19 YsiA-like protein, C-terminal region - - - 0.0000000000000000002473 96.0
TH2_k127_4491635_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 452.0
TH2_k127_4491635_20 MaoC like domain K09709 - 4.2.1.153 0.00000000000000002158 87.0
TH2_k127_4491635_21 Endonuclease containing a URI domain - - - 0.00000000000000004343 87.0
TH2_k127_4491635_22 N-terminal half of MaoC dehydratase - - - 0.0000000000000001236 87.0
TH2_k127_4491635_23 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000003028 81.0
TH2_k127_4491635_24 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000034 73.0
TH2_k127_4491635_25 - - - - 0.00000000004793 67.0
TH2_k127_4491635_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 396.0
TH2_k127_4491635_4 SMART PDZ DHR GLGF domain protein K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 345.0
TH2_k127_4491635_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 303.0
TH2_k127_4491635_6 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001836 297.0
TH2_k127_4491635_7 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001406 272.0
TH2_k127_4491635_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000007471 266.0
TH2_k127_4491635_9 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000001217 234.0
TH2_k127_4503805_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002026 269.0
TH2_k127_4503805_1 Rhomboid family K07059 - - 0.0000000000000000000000000000000000000002355 153.0
TH2_k127_4503805_2 Acyl-CoA synthetase (NDP forming) K01905 - 6.2.1.13 0.000000001003 61.0
TH2_k127_4506143_0 denitrification pathway - - - 3.379e-229 727.0
TH2_k127_4506143_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 598.0
TH2_k127_4506143_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 519.0
TH2_k127_4506143_3 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001087 277.0
TH2_k127_4506143_4 peptidase dimerisation domain protein K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000008738 268.0
TH2_k127_4506143_5 Isochorismatase family - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008936,GO:0009117,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019362,GO:0019637,GO:0019674,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901360,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000001761 207.0
TH2_k127_4506143_6 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000000001327 197.0
TH2_k127_4506143_7 5'-nucleotidase - - - 0.000000000000000000000000000000000000005763 162.0
TH2_k127_4506192_0 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 429.0
TH2_k127_4506192_1 PFAM UBA THIF-type NAD FAD binding protein K03148 - 2.7.7.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 323.0
TH2_k127_4513628_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 9.165e-306 973.0
TH2_k127_4513628_1 Family membership - - - 1.897e-213 702.0
TH2_k127_4513628_10 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 392.0
TH2_k127_4513628_11 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 307.0
TH2_k127_4513628_12 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 302.0
TH2_k127_4513628_13 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 300.0
TH2_k127_4513628_14 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 295.0
TH2_k127_4513628_15 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 294.0
TH2_k127_4513628_16 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008291 283.0
TH2_k127_4513628_17 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000667 274.0
TH2_k127_4513628_18 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000002161 260.0
TH2_k127_4513628_19 FES K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000002187 195.0
TH2_k127_4513628_2 Family membership - - - 5.881e-201 662.0
TH2_k127_4513628_20 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000002885 192.0
TH2_k127_4513628_21 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000002855 190.0
TH2_k127_4513628_22 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000004111 187.0
TH2_k127_4513628_23 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000000003873 171.0
TH2_k127_4513628_24 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000001653 150.0
TH2_k127_4513628_25 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000006901 148.0
TH2_k127_4513628_26 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000001239 139.0
TH2_k127_4513628_27 - - - - 0.000000000000000000000007139 106.0
TH2_k127_4513628_28 Belongs to the universal stress protein A family - - - 0.000000000000000000000007932 107.0
TH2_k127_4513628_29 Protein of unknown function (DUF3426) - - - 0.00000000000000000000001463 112.0
TH2_k127_4513628_3 Bacterial regulatory protein, Fis family - - - 3.631e-200 632.0
TH2_k127_4513628_30 - - - - 0.0000000000000000000002542 108.0
TH2_k127_4513628_31 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000005051 90.0
TH2_k127_4513628_32 TIGRFAM transcriptional regulator, AbrB family - - - 0.00000000000000006875 82.0
TH2_k127_4513628_33 Mut7-C ubiquitin - - - 0.0000000000000003111 81.0
TH2_k127_4513628_34 - - - - 0.00000000000002852 78.0
TH2_k127_4513628_35 Domain of unknown function (DUF4911) - - - 0.00000000001364 68.0
TH2_k127_4513628_36 PFAM Antibiotic biosynthesis monooxygenase - - - 0.0000004685 54.0
TH2_k127_4513628_37 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000001175 55.0
TH2_k127_4513628_38 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0001614 44.0
TH2_k127_4513628_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 563.0
TH2_k127_4513628_5 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 525.0
TH2_k127_4513628_6 Electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 472.0
TH2_k127_4513628_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 465.0
TH2_k127_4513628_8 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 429.0
TH2_k127_4513628_9 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 402.0
TH2_k127_4544037_0 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 3.367e-206 649.0
TH2_k127_4544037_1 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 377.0
TH2_k127_4544037_10 Protein of unknown function (DUF433) - - - 0.000000000000000000002673 94.0
TH2_k127_4544037_11 PIN domain - - - 0.00000000000000000001105 96.0
TH2_k127_4544037_12 toxin-antitoxin pair type II binding - - - 0.0000000000000000006028 89.0
TH2_k127_4544037_13 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000245 85.0
TH2_k127_4544037_14 NfeD-like C-terminal, partner-binding - - - 0.0000000000000002233 85.0
TH2_k127_4544037_15 MerR HTH family regulatory protein - - - 0.000000000000004975 76.0
TH2_k127_4544037_17 methyltransferase - - - 0.000001171 52.0
TH2_k127_4544037_18 - - - - 0.00001409 51.0
TH2_k127_4544037_19 - - - - 0.00001543 51.0
TH2_k127_4544037_2 Protein of unknown function (DUF1016) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 289.0
TH2_k127_4544037_3 PFAM response regulator receiver K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006469 275.0
TH2_k127_4544037_4 PFAM ATP-binding region ATPase domain protein K02484,K07640 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000001603 259.0
TH2_k127_4544037_5 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.00000000000000000000000000000001987 135.0
TH2_k127_4544037_6 reverse transcriptase - - - 0.0000000000000000000000000000001272 131.0
TH2_k127_4544037_7 - - - - 0.0000000000000000000000000002686 117.0
TH2_k127_4544037_8 nuclease activity K06218 - - 0.000000000000000000000000002595 113.0
TH2_k127_4544037_9 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000001016 98.0
TH2_k127_4544989_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 495.0
TH2_k127_4544989_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 378.0
TH2_k127_4544989_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000002061 222.0
TH2_k127_4544989_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000003156 209.0
TH2_k127_4544989_4 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000004977 186.0
TH2_k127_4545890_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.681e-225 706.0
TH2_k127_4545890_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001504 265.0
TH2_k127_4545890_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000001883 152.0
TH2_k127_4548263_0 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000161 233.0
TH2_k127_4548263_1 - - - - 0.000000002042 68.0
TH2_k127_4548263_2 NMT1/THI5 like K02051 - - 0.0008562 43.0
TH2_k127_456821_0 Multicopper oxidase - - - 0.0 1075.0
TH2_k127_456821_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 567.0
TH2_k127_456821_10 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000001367 123.0
TH2_k127_456821_11 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000000005131 113.0
TH2_k127_456821_12 DNA polymerase beta domain protein region - - - 0.000000000000000000000000005969 114.0
TH2_k127_456821_13 COG3666 Transposase and inactivated derivatives - - - 0.00000000000000000118 87.0
TH2_k127_456821_14 Alternative locus ID K09835 - 5.2.1.13 0.000000002164 70.0
TH2_k127_456821_16 Addiction module antidote protein - - - 0.00005738 49.0
TH2_k127_456821_2 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 453.0
TH2_k127_456821_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 372.0
TH2_k127_456821_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 367.0
TH2_k127_456821_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 353.0
TH2_k127_456821_6 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001057 276.0
TH2_k127_456821_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000001799 208.0
TH2_k127_456821_8 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000004862 201.0
TH2_k127_456821_9 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.000000000000000000000000000000000000000003569 162.0
TH2_k127_4603624_0 CHAT domain - - - 2.831e-207 670.0
TH2_k127_4603624_1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 542.0
TH2_k127_4603624_2 N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000002373 249.0
TH2_k127_4603624_3 glucosamine-1-phosphate N-acetyltransferase activity K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000001962 141.0
TH2_k127_4603624_4 COGs COG1487 nucleic acid-binding protein contains PIN domain K18828 - - 0.000000000000000000000000000000001777 134.0
TH2_k127_4603624_5 LmbE family - - - 0.00000000000000000000000000007277 129.0
TH2_k127_4603624_6 LmbE family - - - 0.00000000000000000000000002391 117.0
TH2_k127_4603624_7 cyclic nucleotide-binding - - - 0.00000000000003544 81.0
TH2_k127_4603624_8 - - - - 0.0000003315 56.0
TH2_k127_4640061_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.266e-201 635.0
TH2_k127_4640061_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 314.0
TH2_k127_4640061_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 320.0
TH2_k127_4640061_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 307.0
TH2_k127_4640061_4 radical SAM domain protein K03716 - 4.1.99.14 0.00000000000000000000000000000003428 130.0
TH2_k127_4640061_5 chromosome segregation K03497 - - 0.000000000000000000000007892 113.0
TH2_k127_4640061_6 GIY-YIG catalytic domain K07461 - - 0.000000000000000002806 87.0
TH2_k127_4640061_7 - - - - 0.00000000000000000758 87.0
TH2_k127_4640061_8 - - - - 0.00000005841 56.0
TH2_k127_4652215_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 540.0
TH2_k127_4652215_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 464.0
TH2_k127_4652215_2 SMART AAA ATPase - - - 0.0000000000000000000000000000000000000000002054 178.0
TH2_k127_4652215_3 PAC2 family - - - 0.00000000000000000000000000000000000000001161 164.0
TH2_k127_4652215_4 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000003291 154.0
TH2_k127_4652215_5 - - - - 0.0002575 49.0
TH2_k127_4688438_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.301e-223 700.0
TH2_k127_4688438_1 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 5.318e-208 666.0
TH2_k127_4688438_10 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000004072 196.0
TH2_k127_4688438_11 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000000007501 122.0
TH2_k127_4688438_12 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.000000000000000000000000000002864 127.0
TH2_k127_4688438_13 Protein of unknown function (DUF433) - - - 0.0000000000000000000000001542 107.0
TH2_k127_4688438_14 - - - - 0.000000000000000000000001822 105.0
TH2_k127_4688438_15 PIN domain - - - 0.00000000000000000004985 94.0
TH2_k127_4688438_17 4fe-4S ferredoxin, iron-sulfur binding domain protein K20449 - 1.3.7.1 0.0000000007394 63.0
TH2_k127_4688438_18 PFAM Integrase catalytic region - - - 0.00000007335 54.0
TH2_k127_4688438_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 624.0
TH2_k127_4688438_3 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 529.0
TH2_k127_4688438_4 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 519.0
TH2_k127_4688438_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 398.0
TH2_k127_4688438_6 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 398.0
TH2_k127_4688438_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000002024 231.0
TH2_k127_4688438_8 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000003224 231.0
TH2_k127_4688438_9 AIR synthase related protein, N-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000006071 223.0
TH2_k127_4706313_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1063.0
TH2_k127_4706313_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 8.384e-306 956.0
TH2_k127_4706313_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000005916 184.0
TH2_k127_4706313_11 Jag_N K06346 - - 0.000000000000000000000000000002112 125.0
TH2_k127_4706313_12 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000005675 108.0
TH2_k127_4706313_13 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000000000000000000000006759 104.0
TH2_k127_4706313_14 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000162 71.0
TH2_k127_4706313_15 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000001731 72.0
TH2_k127_4706313_16 translation release factor activity K02835 - - 0.000002218 51.0
TH2_k127_4706313_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.434e-214 673.0
TH2_k127_4706313_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 505.0
TH2_k127_4706313_4 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 450.0
TH2_k127_4706313_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 443.0
TH2_k127_4706313_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 377.0
TH2_k127_4706313_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 330.0
TH2_k127_4706313_8 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 315.0
TH2_k127_4706313_9 Beta-lactamase superfamily domain K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000104 277.0
TH2_k127_4721146_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 4.07e-200 629.0
TH2_k127_4721146_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 619.0
TH2_k127_4721146_10 Dodecin K09165 - - 0.000000000000000000006597 93.0
TH2_k127_4721146_11 glycosyl transferase family 2 K00786 - - 0.000000000002665 68.0
TH2_k127_4721146_2 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 516.0
TH2_k127_4721146_3 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 392.0
TH2_k127_4721146_4 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 369.0
TH2_k127_4721146_5 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 305.0
TH2_k127_4721146_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001744 280.0
TH2_k127_4721146_7 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000008711 249.0
TH2_k127_4721146_8 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.00000000000000000000000000000000000000000000000000003522 188.0
TH2_k127_4721146_9 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00000000000000000000000000000000000005827 146.0
TH2_k127_4728132_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 4.057e-262 814.0
TH2_k127_4728132_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 4.228e-258 811.0
TH2_k127_4728132_10 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 344.0
TH2_k127_4728132_11 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 336.0
TH2_k127_4728132_12 Dehydrogenase K00005 - 1.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 337.0
TH2_k127_4728132_13 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 335.0
TH2_k127_4728132_14 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 312.0
TH2_k127_4728132_15 PFAM Bacterial regulatory proteins, gntR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002219 270.0
TH2_k127_4728132_16 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004541 258.0
TH2_k127_4728132_17 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004577 258.0
TH2_k127_4728132_18 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000009745 246.0
TH2_k127_4728132_19 2-Nitropropane dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000001948 228.0
TH2_k127_4728132_2 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 574.0
TH2_k127_4728132_20 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000001055 221.0
TH2_k127_4728132_21 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000001447 214.0
TH2_k127_4728132_22 TSCPD domain - - - 0.000000000000000000000000000000000000000000000000000484 196.0
TH2_k127_4728132_23 UPF0060 membrane protein K09771 - - 0.0000000000000000000000000000000000000000001625 160.0
TH2_k127_4728132_24 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000001486 161.0
TH2_k127_4728132_25 Cysteine-rich domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000002058 151.0
TH2_k127_4728132_26 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.00000000000000000000000000000000000008907 148.0
TH2_k127_4728132_27 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000698 136.0
TH2_k127_4728132_28 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.0000000000000000000000000000000001959 136.0
TH2_k127_4728132_29 DGC domain - - - 0.000000000000000000000000000000001567 134.0
TH2_k127_4728132_3 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 527.0
TH2_k127_4728132_30 Methyltransferase type 11 - - - 0.0000000000000000000000000001123 125.0
TH2_k127_4728132_31 Uncharacterised BCR, YnfA/UPF0060 family K09771 - - 0.000000000000000000000000001434 114.0
TH2_k127_4728132_32 Transcriptional regulator, MerR family - - - 0.00000000000000000000000008021 113.0
TH2_k127_4728132_33 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000004278 98.0
TH2_k127_4728132_34 glycine decarboxylation via glycine cleavage system K02437 - - 0.00000000000000000001412 98.0
TH2_k127_4728132_35 DGC domain - - - 0.0000000000000002008 85.0
TH2_k127_4728132_36 - - - - 0.0000000000000002821 80.0
TH2_k127_4728132_37 - - - - 0.000000000000004049 78.0
TH2_k127_4728132_39 DGC domain - - - 0.00000000008467 70.0
TH2_k127_4728132_4 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006862 471.0
TH2_k127_4728132_40 DGC domain - - - 0.0000000004355 67.0
TH2_k127_4728132_42 Uroporphyrinogen decarboxylase K01599 - 4.1.1.37 0.00002461 49.0
TH2_k127_4728132_43 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.00002471 48.0
TH2_k127_4728132_44 The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005960,GO:0006082,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006730,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009249,GO:0009987,GO:0010467,GO:0016054,GO:0017144,GO:0018065,GO:0018193,GO:0018205,GO:0019464,GO:0019538,GO:0019752,GO:0032991,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051604,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 - 0.0008329 48.0
TH2_k127_4728132_45 Thiamine biosynthesis protein K03154 - - 0.0009015 46.0
TH2_k127_4728132_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 436.0
TH2_k127_4728132_6 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 378.0
TH2_k127_4728132_7 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080,K14082 - 2.1.1.246,2.1.1.247,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 374.0
TH2_k127_4728132_8 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 369.0
TH2_k127_4728132_9 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 352.0
TH2_k127_4728766_0 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 403.0
TH2_k127_4728766_1 COG0191 Fructose tagatose bisphosphate aldolase K01624,K08302 - 4.1.2.13,4.1.2.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 371.0
TH2_k127_4728766_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 325.0
TH2_k127_4728766_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000002537 218.0
TH2_k127_4728766_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000002607 162.0
TH2_k127_4728766_5 Putative transmembrane protein (PGPGW) - - - 0.000000000001081 72.0
TH2_k127_4728766_6 - - - - 0.00000000002045 71.0
TH2_k127_4728766_7 - - - - 0.000683 47.0
TH2_k127_4735287_0 acetyltransferase K19113 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 449.0
TH2_k127_4735287_1 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 374.0
TH2_k127_4735287_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 302.0
TH2_k127_4735287_3 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000001236 218.0
TH2_k127_4735287_4 CoA-transferase family III - - - 0.00000000000000000000000000009575 116.0
TH2_k127_4735287_5 CoA-transferase family III - - - 0.0000000000000000002675 88.0
TH2_k127_475107_0 Psort location Cytoplasmic, score - - - 0.0 1587.0
TH2_k127_475107_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0 1161.0
TH2_k127_475107_10 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 307.0
TH2_k127_475107_11 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 295.0
TH2_k127_475107_12 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004003 275.0
TH2_k127_475107_13 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000004958 273.0
TH2_k127_475107_14 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002001 271.0
TH2_k127_475107_15 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000002472 206.0
TH2_k127_475107_16 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000003814 184.0
TH2_k127_475107_17 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000002458 144.0
TH2_k127_475107_18 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000000000009669 119.0
TH2_k127_475107_19 - - - - 0.000000000000000006324 86.0
TH2_k127_475107_2 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.0 1156.0
TH2_k127_475107_3 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 2.211e-297 924.0
TH2_k127_475107_4 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 569.0
TH2_k127_475107_5 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 430.0
TH2_k127_475107_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 439.0
TH2_k127_475107_7 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 405.0
TH2_k127_475107_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 358.0
TH2_k127_475107_9 Pterin binding enzyme K15023 - 2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 359.0
TH2_k127_4762859_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002378 272.0
TH2_k127_4762859_1 PIN domain - - - 0.000000000000000000000009045 106.0
TH2_k127_4762859_2 - - - - 0.000000000009821 70.0
TH2_k127_4762859_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - 0.0000000000152 75.0
TH2_k127_4769376_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 7.478e-229 719.0
TH2_k127_4769376_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 431.0
TH2_k127_4769376_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 299.0
TH2_k127_4769376_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000002119 216.0
TH2_k127_4769376_4 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000006654 151.0
TH2_k127_4769376_5 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000002696 142.0
TH2_k127_4769376_6 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000001301 82.0
TH2_k127_4794793_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.347e-245 772.0
TH2_k127_4794793_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 593.0
TH2_k127_4794793_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 535.0
TH2_k127_4794793_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 338.0
TH2_k127_4794793_4 Pyridoxal-phosphate dependent enzyme K01883,K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 289.0
TH2_k127_4794793_5 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000266 177.0
TH2_k127_4794793_6 Rhodanese domain protein K01011 GO:0005575,GO:0005623,GO:0042597,GO:0044464 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000001111 180.0
TH2_k127_4794793_7 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.000000000000000000000003566 102.0
TH2_k127_4794793_8 PIN domain K07065 - - 0.00000000000000000002555 95.0
TH2_k127_4795022_0 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 3.73e-198 637.0
TH2_k127_4795022_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 407.0
TH2_k127_4795022_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004201 254.0
TH2_k127_4795022_3 alpha-ribazole phosphatase activity K01834,K15634,K22306 - 3.1.3.85,5.4.2.11,5.4.2.12 0.0000000000000000000000000000000001842 139.0
TH2_k127_4795067_0 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 560.0
TH2_k127_4795067_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 417.0
TH2_k127_4795067_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001343 250.0
TH2_k127_4795067_3 alpha-ribazole phosphatase activity K01834,K15634,K22306 - 3.1.3.85,5.4.2.11,5.4.2.12 0.00000000000000000000000000000000002179 143.0
TH2_k127_4802350_0 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 502.0
TH2_k127_4802350_1 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 457.0
TH2_k127_4802350_10 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000006663 126.0
TH2_k127_4802350_11 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000718 123.0
TH2_k127_4802350_12 SMART Tetratricopeptide - - - 0.0000000000000000000000003251 117.0
TH2_k127_4802350_13 - - - - 0.000000000000000000000005104 108.0
TH2_k127_4802350_14 cheY-homologous receiver domain K02657 - - 0.000000000000000000000005928 105.0
TH2_k127_4802350_15 - - - - 0.000000000000000000005986 99.0
TH2_k127_4802350_16 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000006256 69.0
TH2_k127_4802350_17 PFAM NADPH-dependent FMN reductase - - - 0.0002999 44.0
TH2_k127_4802350_2 NnrS protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 368.0
TH2_k127_4802350_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 332.0
TH2_k127_4802350_4 Flavodoxin domain K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000003819 246.0
TH2_k127_4802350_5 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000003934 206.0
TH2_k127_4802350_6 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000007043 194.0
TH2_k127_4802350_7 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000001244 177.0
TH2_k127_4802350_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000001685 167.0
TH2_k127_4802350_9 PFAM pyridoxamine 5-phosphate oxidase-related FMN-binding - - - 0.0000000000000000000000000000000000000001644 154.0
TH2_k127_4830311_0 B-1 B cell differentiation - - - 1.094e-266 843.0
TH2_k127_4830311_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 5.782e-201 640.0
TH2_k127_4830311_10 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 296.0
TH2_k127_4830311_11 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 294.0
TH2_k127_4830311_12 B-1 B cell differentiation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005143 242.0
TH2_k127_4830311_13 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000009246 200.0
TH2_k127_4830311_14 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000001853 118.0
TH2_k127_4830311_15 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000005052 59.0
TH2_k127_4830311_16 - - - - 0.00000003936 61.0
TH2_k127_4830311_2 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 604.0
TH2_k127_4830311_3 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 373.0
TH2_k127_4830311_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 368.0
TH2_k127_4830311_5 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 353.0
TH2_k127_4830311_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 344.0
TH2_k127_4830311_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 338.0
TH2_k127_4830311_8 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 325.0
TH2_k127_4830311_9 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 311.0
TH2_k127_4897780_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007381 282.0
TH2_k127_4897780_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001374 251.0
TH2_k127_4897780_2 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000008996 187.0
TH2_k127_4897780_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000003021 121.0
TH2_k127_4914891_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 578.0
TH2_k127_4914891_1 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 348.0
TH2_k127_4914891_10 COGs COG1569 nucleic acid-binding protein contains PIN domain - - - 0.0000000006215 63.0
TH2_k127_4914891_11 sequence-specific DNA binding - - - 0.00000009992 56.0
TH2_k127_4914891_13 Acetyltransferase (GNAT) domain - - - 0.0005136 48.0
TH2_k127_4914891_2 WYL domain K13573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001038 262.0
TH2_k127_4914891_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001395 255.0
TH2_k127_4914891_4 HD domain - - - 0.00000000000000000000000000000000000000000000000000000004687 205.0
TH2_k127_4914891_5 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000001485 188.0
TH2_k127_4914891_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000005864 133.0
TH2_k127_4914891_7 UV-endonuclease UvdE - - - 0.00000000000000001258 86.0
TH2_k127_4914891_8 PFAM SpoVT AbrB - - - 0.000000000000003438 78.0
TH2_k127_4914891_9 PFAM Helix-turn-helix - - - 0.000000000001421 76.0
TH2_k127_4922267_0 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 599.0
TH2_k127_4922267_1 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 492.0
TH2_k127_4922267_10 Thioredoxin-like - - - 0.0000000000000000000000000000000001608 138.0
TH2_k127_4922267_11 SCO1/SenC - - - 0.000000000000000000000000000007203 127.0
TH2_k127_4922267_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 482.0
TH2_k127_4922267_3 Arginase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 400.0
TH2_k127_4922267_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 301.0
TH2_k127_4922267_5 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005214 271.0
TH2_k127_4922267_6 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000429 261.0
TH2_k127_4922267_7 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000007168 224.0
TH2_k127_4922267_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.00000000000000000000000000000000000000000000000000000000000001459 223.0
TH2_k127_4922267_9 transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000004274 199.0
TH2_k127_4954336_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 501.0
TH2_k127_4954336_1 Belongs to the DegT DnrJ EryC1 family K16436 - 2.6.1.106 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 424.0
TH2_k127_4954336_2 PFAM Glycosyl transferase, group 1 K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 314.0
TH2_k127_4954336_3 COG0859 ADP-heptose LPS heptosyltransferase K02841,K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003376 285.0
TH2_k127_4954336_4 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001569 269.0
TH2_k127_4954336_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004712 265.0
TH2_k127_4954336_6 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000000000003211 126.0
TH2_k127_4954336_7 Bacterial transferase hexapeptide (six repeats) K08280 - - 0.00000007956 58.0
TH2_k127_4960444_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1184.0
TH2_k127_4960444_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 9.38e-286 902.0
TH2_k127_4960444_10 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 291.0
TH2_k127_4960444_11 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004118 271.0
TH2_k127_4960444_12 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005613 235.0
TH2_k127_4960444_13 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000001322 233.0
TH2_k127_4960444_14 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000002903 222.0
TH2_k127_4960444_15 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000001043 215.0
TH2_k127_4960444_16 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000001124 187.0
TH2_k127_4960444_17 Lysin motif K06194 - - 0.00000000000000000000000000000000000000000001058 171.0
TH2_k127_4960444_18 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000009552 156.0
TH2_k127_4960444_19 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000242 130.0
TH2_k127_4960444_2 Threonyl and Alanyl tRNA synthetase second additional domain K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 3.935e-272 850.0
TH2_k127_4960444_20 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000007154 110.0
TH2_k127_4960444_21 helix_turn_helix, mercury resistance - - - 0.000000000000000000000001388 107.0
TH2_k127_4960444_22 Protein of unknown function (DUF1232) - - - 0.0000000000000000000003958 96.0
TH2_k127_4960444_23 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000005824 83.0
TH2_k127_4960444_24 Belongs to the UPF0145 family - - - 0.0000000000002171 76.0
TH2_k127_4960444_25 Protein of unknown function (DUF1232) - - - 0.000000001674 60.0
TH2_k127_4960444_26 Belongs to the 'phage' integrase family - - - 0.00003666 47.0
TH2_k127_4960444_27 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000243 52.0
TH2_k127_4960444_3 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.498e-239 764.0
TH2_k127_4960444_4 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 3.855e-214 670.0
TH2_k127_4960444_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 492.0
TH2_k127_4960444_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 447.0
TH2_k127_4960444_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 388.0
TH2_k127_4960444_8 PFAM Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 348.0
TH2_k127_4960444_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 298.0
TH2_k127_4985728_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1231.0
TH2_k127_4985728_1 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1203.0
TH2_k127_4985728_10 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 539.0
TH2_k127_4985728_11 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 520.0
TH2_k127_4985728_12 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 513.0
TH2_k127_4985728_13 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 487.0
TH2_k127_4985728_14 ferredoxin oxidoreductase K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 467.0
TH2_k127_4985728_15 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 474.0
TH2_k127_4985728_16 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 421.0
TH2_k127_4985728_17 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 385.0
TH2_k127_4985728_18 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 381.0
TH2_k127_4985728_19 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 371.0
TH2_k127_4985728_2 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 8.359e-289 897.0
TH2_k127_4985728_20 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 328.0
TH2_k127_4985728_21 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 323.0
TH2_k127_4985728_22 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 322.0
TH2_k127_4985728_23 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 304.0
TH2_k127_4985728_24 Belongs to the arginase family K01480,K18459 - 3.5.3.11,3.5.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 303.0
TH2_k127_4985728_25 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 308.0
TH2_k127_4985728_26 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 290.0
TH2_k127_4985728_27 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007337 290.0
TH2_k127_4985728_28 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 283.0
TH2_k127_4985728_29 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003867 273.0
TH2_k127_4985728_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 4.587e-277 864.0
TH2_k127_4985728_30 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001104 283.0
TH2_k127_4985728_31 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001927 263.0
TH2_k127_4985728_32 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005235 256.0
TH2_k127_4985728_33 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000002333 244.0
TH2_k127_4985728_34 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001038 238.0
TH2_k127_4985728_35 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000001936 241.0
TH2_k127_4985728_36 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003788 243.0
TH2_k127_4985728_37 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000001203 226.0
TH2_k127_4985728_38 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000399 218.0
TH2_k127_4985728_39 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000001136 214.0
TH2_k127_4985728_4 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 5.567e-263 814.0
TH2_k127_4985728_40 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000005101 209.0
TH2_k127_4985728_41 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000003275 196.0
TH2_k127_4985728_43 PFAM Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000002684 192.0
TH2_k127_4985728_44 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000764 176.0
TH2_k127_4985728_45 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000000006512 178.0
TH2_k127_4985728_46 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000002093 172.0
TH2_k127_4985728_47 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.00000000000000000000000000000000000000000007217 164.0
TH2_k127_4985728_48 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000004447 158.0
TH2_k127_4985728_49 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000003053 151.0
TH2_k127_4985728_5 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 3.013e-245 764.0
TH2_k127_4985728_50 Pyruvate ferredoxin oxidoreductase K00171 - 1.2.7.1 0.0000000000000000000000000000000000000209 145.0
TH2_k127_4985728_51 YbaB/EbfC DNA-binding family K09747 - - 0.00000000000000000000000000000000000002122 145.0
TH2_k127_4985728_52 Nucleotide binding protein, PINc - - - 0.000000000000000000000000000000000003454 141.0
TH2_k127_4985728_53 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000003024 135.0
TH2_k127_4985728_54 Sporulation and spore germination - - - 0.0000000000000000000000000002375 121.0
TH2_k127_4985728_55 Domain of unknown function (DUF4870) - - - 0.0000000000000000000000000008334 116.0
TH2_k127_4985728_56 Domain of unknown function DUF120 K01091 - 3.1.3.18 0.000000000000000000000006447 105.0
TH2_k127_4985728_57 OmpA family - - - 0.0000000000000000000888 98.0
TH2_k127_4985728_58 DUF167 K09131 - - 0.0000000000000000001698 91.0
TH2_k127_4985728_59 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000002135 83.0
TH2_k127_4985728_6 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 1.371e-226 705.0
TH2_k127_4985728_60 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000003111 83.0
TH2_k127_4985728_61 PFAM flavin reductase domain protein FMN-binding - - - 0.000000000000001137 83.0
TH2_k127_4985728_62 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) - - - 0.000000000000004443 81.0
TH2_k127_4985728_63 EamA-like transporter family - - - 0.000000000007308 68.0
TH2_k127_4985728_64 PFAM Integrase catalytic region - - - 0.0000001772 54.0
TH2_k127_4985728_65 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000003262 52.0
TH2_k127_4985728_67 EamA-like transporter family - - - 0.000001186 55.0
TH2_k127_4985728_7 Transposase DDE domain - - - 5.378e-198 629.0
TH2_k127_4985728_70 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00004098 46.0
TH2_k127_4985728_71 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 - - - 0.0004156 47.0
TH2_k127_4985728_72 Resolvase, N terminal domain - - - 0.0008195 42.0
TH2_k127_4985728_8 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 578.0
TH2_k127_4985728_9 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 556.0
TH2_k127_5002319_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 542.0
TH2_k127_5002319_1 Triosephosphate isomerase K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007778 317.0
TH2_k127_5002319_2 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001485 278.0
TH2_k127_5002319_3 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000002211 260.0
TH2_k127_5002319_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004022 265.0
TH2_k127_5002319_5 - - - - 0.00000000000000000000000000000000001593 149.0
TH2_k127_5002319_6 regulatory protein, FmdB family - - - 0.00000000000000844 76.0
TH2_k127_5002319_7 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000007165 60.0
TH2_k127_5006922_0 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 297.0
TH2_k127_5006922_1 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000001724 209.0
TH2_k127_5006922_2 Psort location CytoplasmicMembrane, score - - - 0.00000000007862 68.0
TH2_k127_5034375_0 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 447.0
TH2_k127_5034375_1 PFAM Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 330.0
TH2_k127_5034375_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 304.0
TH2_k127_5034375_3 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000892 282.0
TH2_k127_5034375_4 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008621 261.0
TH2_k127_5034375_5 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001361 248.0
TH2_k127_5034375_6 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000001741 231.0
TH2_k127_5034375_7 Ndr family K00433,K01055 - 1.11.1.10,3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000001924 222.0
TH2_k127_5034375_8 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000002593 203.0
TH2_k127_5034375_9 Serine aminopeptidase, S33 K19707 - - 0.00000000000000000000000000000000000000000000004183 179.0
TH2_k127_5039917_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 447.0
TH2_k127_5039917_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 425.0
TH2_k127_5039917_2 DisA bacterial checkpoint controller nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009581 250.0
TH2_k127_5039917_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000003131 233.0
TH2_k127_5039917_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000005359 203.0
TH2_k127_5039917_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000002167 193.0
TH2_k127_5039917_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000008034 181.0
TH2_k127_5039917_7 Could be involved in septation K06412 - - 0.0000000000000000000000000000000000187 137.0
TH2_k127_5039917_8 4Fe-4S binding domain - - - 0.000000000000000006412 84.0
TH2_k127_5039917_9 TPR Domain containing protein K12600 - - 0.000000000008292 73.0
TH2_k127_5055172_0 C4-dicarboxylate ABC transporter permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 425.0
TH2_k127_5055172_1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 361.0
TH2_k127_5055172_10 PFAM band 7 protein - - - 0.00000000000133 73.0
TH2_k127_5055172_11 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.000000000002235 74.0
TH2_k127_5055172_12 - - - - 0.000255 47.0
TH2_k127_5055172_13 PIN domain - - - 0.0004335 47.0
TH2_k127_5055172_2 Nuclease-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 337.0
TH2_k127_5055172_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000003053 267.0
TH2_k127_5055172_4 carbohydrate transport K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002568 258.0
TH2_k127_5055172_5 HD domain - - - 0.0000000000000000000000000000000000000000000001597 171.0
TH2_k127_5055172_6 PIN domain - - - 0.00000000000000000000000000003179 121.0
TH2_k127_5055172_7 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000006495 104.0
TH2_k127_5055172_8 PFAM glycoside hydrolase, family 13 domain protein - - - 0.000000000000000008936 87.0
TH2_k127_5055172_9 PFAM SpoVT AbrB - - - 0.000000000000000017 84.0
TH2_k127_5059694_0 glycosyl transferase family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 560.0
TH2_k127_5059694_1 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 537.0
TH2_k127_5059694_2 haloacid dehalogenase-like hydrolase K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000006 269.0
TH2_k127_5059694_3 PFAM Glycosyl transferase family 2 K12990 - - 0.0000000000000000000000000000000000000000000000000000000002365 217.0
TH2_k127_5059694_4 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000002324 193.0
TH2_k127_5059694_5 PTS system fructose IIA component K02793 - 2.7.1.191 0.00000000000000000000000000009296 119.0
TH2_k127_5059694_6 cheY-homologous receiver domain - - - 0.00000000000000000001116 96.0
TH2_k127_5059694_7 - - - - 0.00000000000004131 74.0
TH2_k127_5059694_8 response regulator - - - 0.00000003091 59.0
TH2_k127_5059694_9 Pfam:DUF1049 - - - 0.00004446 49.0
TH2_k127_5066197_0 PFAM Phosphate-starvation-inducible - - - 0.0000000000000000000000000000000000000000000000000000000000128 209.0
TH2_k127_5066197_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000005357 115.0
TH2_k127_5066197_2 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000001737 100.0
TH2_k127_5066197_3 - - - - 0.0000000000000000000002384 100.0
TH2_k127_5066197_4 Amidohydrolase family - - - 0.00000000000002188 75.0
TH2_k127_5087261_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002728 280.0
TH2_k127_5087261_1 Domain of unknown function (DUF697) - - - 0.000000000000000000000000000000000000000000000000000501 196.0
TH2_k127_5087261_2 NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000008439 174.0
TH2_k127_5087261_3 - - - - 0.00000000000000533 76.0
TH2_k127_511622_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 588.0
TH2_k127_511622_1 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 325.0
TH2_k127_511622_2 Periplasmic binding protein K01999 - - 0.0000000000000000000000001719 117.0
TH2_k127_5169140_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 354.0
TH2_k127_5169140_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000001163 154.0
TH2_k127_5169140_2 TIGRFAM DNA binding domain, excisionase family - - - 0.00003002 48.0
TH2_k127_5172914_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 434.0
TH2_k127_5172914_1 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 374.0
TH2_k127_5172914_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 286.0
TH2_k127_5172914_3 FCD K05799 - - 0.000000000000000000000000000000000000000000000003199 181.0
TH2_k127_5172914_4 Universal stress protein family - - - 0.00000000000000000000001479 107.0
TH2_k127_5242023_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1018.0
TH2_k127_5242023_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.246e-215 679.0
TH2_k127_5242023_10 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 460.0
TH2_k127_5242023_11 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 453.0
TH2_k127_5242023_12 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 427.0
TH2_k127_5242023_13 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 425.0
TH2_k127_5242023_14 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 383.0
TH2_k127_5242023_15 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 378.0
TH2_k127_5242023_16 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 368.0
TH2_k127_5242023_17 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 373.0
TH2_k127_5242023_18 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 366.0
TH2_k127_5242023_19 nitrogen compound transport K02033,K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 325.0
TH2_k127_5242023_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 8.773e-201 642.0
TH2_k127_5242023_20 Sugar-transfer associated ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 320.0
TH2_k127_5242023_21 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 319.0
TH2_k127_5242023_22 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 307.0
TH2_k127_5242023_23 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 304.0
TH2_k127_5242023_24 Radical_SAM C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 297.0
TH2_k127_5242023_25 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 304.0
TH2_k127_5242023_26 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004054 281.0
TH2_k127_5242023_27 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005443 256.0
TH2_k127_5242023_28 PFAM ApbE family K09740 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002083 252.0
TH2_k127_5242023_29 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002942 248.0
TH2_k127_5242023_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.876e-198 625.0
TH2_k127_5242023_30 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000113 252.0
TH2_k127_5242023_31 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000001001 241.0
TH2_k127_5242023_32 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000001612 243.0
TH2_k127_5242023_33 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000002409 227.0
TH2_k127_5242023_34 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000004221 227.0
TH2_k127_5242023_35 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.0000000000000000000000000000000000000000000000000000000000000001619 241.0
TH2_k127_5242023_36 Cyclic nucleotide-monophosphate binding domain K04739 - - 0.00000000000000000000000000000000000000000000000000000000000001626 230.0
TH2_k127_5242023_37 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000002554 218.0
TH2_k127_5242023_38 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000003464 217.0
TH2_k127_5242023_39 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000002114 220.0
TH2_k127_5242023_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 8.868e-197 624.0
TH2_k127_5242023_40 protein conserved in bacteria K09778 - - 0.0000000000000000000000000000000000000000000000000002418 193.0
TH2_k127_5242023_41 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000002446 188.0
TH2_k127_5242023_42 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000001081 188.0
TH2_k127_5242023_43 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000008163 165.0
TH2_k127_5242023_44 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.0000000000000000000000000000000000000001583 153.0
TH2_k127_5242023_45 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000001004 150.0
TH2_k127_5242023_46 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000000000000009809 119.0
TH2_k127_5242023_47 electron transfer activity K00428 - 1.11.1.5 0.000000000000000000000004697 104.0
TH2_k127_5242023_48 Putative ATP-dependant zinc protease - - - 0.000000000000000001306 92.0
TH2_k127_5242023_49 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000002889 75.0
TH2_k127_5242023_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 589.0
TH2_k127_5242023_50 COG0247 Fe-S oxidoreductase - - - 0.000000000000107 85.0
TH2_k127_5242023_52 Phage integrase family - - - 0.000134 44.0
TH2_k127_5242023_6 Domain of unknown function (DUF4301) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009512 573.0
TH2_k127_5242023_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 543.0
TH2_k127_5242023_8 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 518.0
TH2_k127_5242023_9 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 460.0
TH2_k127_5308750_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 3.771e-227 724.0
TH2_k127_5308750_1 Bacterial extracellular solute-binding protein K02012 - - 8.533e-203 635.0
TH2_k127_5308750_10 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 318.0
TH2_k127_5308750_11 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 287.0
TH2_k127_5308750_12 Sensory domain found in PocR K07720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003307 288.0
TH2_k127_5308750_13 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002594 280.0
TH2_k127_5308750_14 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002875 270.0
TH2_k127_5308750_15 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006674 251.0
TH2_k127_5308750_16 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000001707 230.0
TH2_k127_5308750_17 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000044 231.0
TH2_k127_5308750_18 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000002081 232.0
TH2_k127_5308750_19 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000001652 231.0
TH2_k127_5308750_2 Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 575.0
TH2_k127_5308750_20 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000002822 238.0
TH2_k127_5308750_21 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000003501 217.0
TH2_k127_5308750_22 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000002756 219.0
TH2_k127_5308750_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000935 213.0
TH2_k127_5308750_24 COGs COG1144 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase delta subunit K00171,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000005576 208.0
TH2_k127_5308750_25 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000001578 200.0
TH2_k127_5308750_26 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000007684 194.0
TH2_k127_5308750_27 cobalamin binding K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000005509 192.0
TH2_k127_5308750_28 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000004554 182.0
TH2_k127_5308750_29 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000001436 160.0
TH2_k127_5308750_3 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 561.0
TH2_k127_5308750_30 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000002808 156.0
TH2_k127_5308750_31 Regulatory protein GntR HTH K05799 - - 0.000000000000000000000000000000000005028 146.0
TH2_k127_5308750_32 PFAM Bacterial regulatory proteins, gntR family - - - 0.00000000000000000000000000000001312 135.0
TH2_k127_5308750_33 4Fe-4S dicluster domain - - - 0.000000000000000000000000007955 115.0
TH2_k127_5308750_34 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000003176 102.0
TH2_k127_5308750_35 4Fe-4S dicluster domain - - - 0.000000000000000000001853 98.0
TH2_k127_5308750_36 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000003113 79.0
TH2_k127_5308750_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 471.0
TH2_k127_5308750_5 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 471.0
TH2_k127_5308750_6 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 423.0
TH2_k127_5308750_7 Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 407.0
TH2_k127_5308750_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 354.0
TH2_k127_5308750_9 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 349.0
TH2_k127_5311598_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001342 267.0
TH2_k127_5311598_1 - - - - 0.0000000000000000000000000000009036 125.0
TH2_k127_5320680_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 470.0
TH2_k127_5320680_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 350.0
TH2_k127_5320680_2 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000000000000000000001215 220.0
TH2_k127_5320680_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000003339 155.0
TH2_k127_5320680_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000002014 132.0
TH2_k127_5320680_5 cellulase activity - - - 0.000000000000007407 76.0
TH2_k127_5327741_0 TIGRFAM FemAB-related protein, PEP-CTERM system-associated - - - 0.0000000000000000000000000000000000000000000000000000000000002728 219.0
TH2_k127_5327741_1 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000000000000000000001641 197.0
TH2_k127_5327741_10 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000197 50.0
TH2_k127_5327741_2 nucleotidyltransferase activity K07076 - - 0.0000000000000000000000000000000000000000000001021 171.0
TH2_k127_5327741_3 PIN domain - - - 0.0000000000000000000000000000000000007644 144.0
TH2_k127_5327741_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000002799 136.0
TH2_k127_5327741_5 nuclease activity K06218 - - 0.00000000000000000000000001222 110.0
TH2_k127_5327741_6 PFAM Plasmid maintenance system killer protein - - - 0.0000000000000000000000002606 108.0
TH2_k127_5327741_7 - - - - 0.00000000000000000000274 94.0
TH2_k127_5327741_8 Protein of unknown function DUF86 - - - 0.000000003156 57.0
TH2_k127_5327741_9 - - - - 0.0000136 50.0
TH2_k127_5353234_0 Stage II sporulation K07315 - 3.1.3.3 1.062e-215 687.0
TH2_k127_5353234_1 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 381.0
TH2_k127_5353234_2 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004559 241.0
TH2_k127_5353234_3 anti-sigma regulatory factor K04757 - 2.7.11.1 0.00000000000000000000000000000002505 130.0
TH2_k127_538815_0 protocatechuate 3,4-dioxygenase activity K03333 - 1.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000005389 242.0
TH2_k127_538815_1 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000005866 222.0
TH2_k127_538815_2 Histidine kinase HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000008609 220.0
TH2_k127_538815_3 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000002456 166.0
TH2_k127_538815_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000001398 161.0
TH2_k127_538815_5 Amidohydrolase K01686 - 4.2.1.8 0.00000000000000000000000007498 120.0
TH2_k127_54162_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 396.0
TH2_k127_54162_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 364.0
TH2_k127_54162_2 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 291.0
TH2_k127_54162_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009588 259.0
TH2_k127_54162_4 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000001309 232.0
TH2_k127_54162_5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000216 176.0
TH2_k127_54162_6 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000001886 141.0
TH2_k127_54162_7 - - - - 0.000000000000000000000000001815 121.0
TH2_k127_543462_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 1.423e-242 756.0
TH2_k127_543462_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 4.681e-214 681.0
TH2_k127_543462_10 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 466.0
TH2_k127_543462_11 conserved protein (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 459.0
TH2_k127_543462_12 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 445.0
TH2_k127_543462_13 proline dipeptidase activity K18829 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 412.0
TH2_k127_543462_14 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 405.0
TH2_k127_543462_15 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 373.0
TH2_k127_543462_16 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 367.0
TH2_k127_543462_17 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 369.0
TH2_k127_543462_18 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 361.0
TH2_k127_543462_19 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 355.0
TH2_k127_543462_2 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 606.0
TH2_k127_543462_20 carbohydrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 353.0
TH2_k127_543462_21 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 338.0
TH2_k127_543462_22 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008312 335.0
TH2_k127_543462_23 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 332.0
TH2_k127_543462_24 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 320.0
TH2_k127_543462_25 Glucose dehydrogenase C-terminus K00008,K00060 - 1.1.1.103,1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 315.0
TH2_k127_543462_26 transport system periplasmic component K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 313.0
TH2_k127_543462_27 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 312.0
TH2_k127_543462_28 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003032 298.0
TH2_k127_543462_29 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001556 275.0
TH2_k127_543462_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009427 607.0
TH2_k127_543462_30 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000007286 243.0
TH2_k127_543462_31 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000688 241.0
TH2_k127_543462_32 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000003346 241.0
TH2_k127_543462_33 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000001149 229.0
TH2_k127_543462_34 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000005868 219.0
TH2_k127_543462_35 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000001056 214.0
TH2_k127_543462_36 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000000000000000001406 203.0
TH2_k127_543462_37 - - - - 0.000000000000000000000000000000000000000000000000007755 186.0
TH2_k127_543462_38 Calcineurin-like phosphoesterase superfamily domain K07096 - - 0.0000000000000000000000000000000000000000000000141 181.0
TH2_k127_543462_39 ferredoxin oxidoreductase, subunit gamma K00177 - 1.2.7.3 0.000000000000000000000000000000000000001524 153.0
TH2_k127_543462_4 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 590.0
TH2_k127_543462_40 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000002346 139.0
TH2_k127_543462_41 Putative TM nitroreductase - - - 0.00000000000000000000000000000000004871 139.0
TH2_k127_543462_42 GntR family - - - 0.0000000000000000000000000000008688 129.0
TH2_k127_543462_43 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000002994 132.0
TH2_k127_543462_44 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000001521 132.0
TH2_k127_543462_45 4Fe-4S dicluster domain K08358 - - 0.00000000000000000000000003409 115.0
TH2_k127_543462_46 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000002785 110.0
TH2_k127_543462_47 4 iron, 4 sulfur cluster binding K00176,K05524 - 1.2.7.3 0.0000000000000000000176 93.0
TH2_k127_543462_48 - - - - 0.000000000000000003328 88.0
TH2_k127_543462_49 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000004408 80.0
TH2_k127_543462_5 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 542.0
TH2_k127_543462_50 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000005283 81.0
TH2_k127_543462_51 - - - - 0.0000000000009285 72.0
TH2_k127_543462_52 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000008223 66.0
TH2_k127_543462_53 Transcriptional regulator - - - 0.0000000001397 64.0
TH2_k127_543462_54 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000002519 71.0
TH2_k127_543462_55 FCD - - - 0.0000001812 54.0
TH2_k127_543462_56 Tripartite tricarboxylate transporter TctB family - - - 0.000007687 54.0
TH2_k127_543462_6 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 544.0
TH2_k127_543462_7 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 486.0
TH2_k127_543462_8 ABC transporter K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 463.0
TH2_k127_543462_9 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 472.0
TH2_k127_55010_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1130.0
TH2_k127_55010_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 5.659e-277 868.0
TH2_k127_55010_2 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 531.0
TH2_k127_55010_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 416.0
TH2_k127_55010_4 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 304.0
TH2_k127_55010_5 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000001947 226.0
TH2_k127_55010_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124,K07307 - - 0.0000000000000000000000000000000000000000000000000009509 189.0
TH2_k127_55010_7 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000009765 145.0
TH2_k127_55010_8 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000001222 109.0
TH2_k127_55010_9 belongs to the sigma-70 factor family - - - 0.00000002735 61.0
TH2_k127_556180_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 370.0
TH2_k127_556180_1 helix_turn_helix, Lux Regulon K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000009467 239.0
TH2_k127_556180_2 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001041 256.0
TH2_k127_556180_3 PFAM S23 ribosomal protein - - - 0.00000000000000000000000000000000004445 137.0
TH2_k127_556180_4 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000008208 137.0
TH2_k127_556180_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000006385 126.0
TH2_k127_556180_6 YtkA-like - - - 0.000000000001309 72.0
TH2_k127_5564427_0 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 428.0
TH2_k127_5564427_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 400.0
TH2_k127_5564427_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 306.0
TH2_k127_5564427_3 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000033 224.0
TH2_k127_5590555_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 1.38e-246 771.0
TH2_k127_5590555_1 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 612.0
TH2_k127_5590555_10 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000005627 96.0
TH2_k127_5590555_11 - - - - 0.000000000000009593 75.0
TH2_k127_5590555_12 oxidase, subunit IV K02277 - 1.9.3.1 0.000000000006074 68.0
TH2_k127_5590555_13 response regulator - - - 0.00000002972 57.0
TH2_k127_5590555_14 prohibitin homologues - - - 0.000003222 49.0
TH2_k127_5590555_15 - - - - 0.00001479 50.0
TH2_k127_5590555_16 SPFH Band 7 PHB domain protein - - - 0.0002263 45.0
TH2_k127_5590555_17 Polysulphide reductase, NrfD K00185 - - 0.0008684 44.0
TH2_k127_5590555_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 331.0
TH2_k127_5590555_3 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 299.0
TH2_k127_5590555_4 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003637 261.0
TH2_k127_5590555_5 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000005605 236.0
TH2_k127_5590555_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000007705 229.0
TH2_k127_5590555_7 S23 ribosomal protein - - - 0.000000000000000000000000000000000000000000000000002323 184.0
TH2_k127_5590555_8 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000007834 125.0
TH2_k127_5590555_9 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000008633 101.0
TH2_k127_560085_0 Seven times multi-haem cytochrome CxxCH - - - 1.843e-209 661.0
TH2_k127_560085_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002083 235.0
TH2_k127_560085_2 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000071 147.0
TH2_k127_560085_3 Cytochrome c K08738 - - 0.0000000000000000000000000000001638 131.0
TH2_k127_5621395_0 DNA photolyase K01669 - 4.1.99.3 1.335e-208 657.0
TH2_k127_5621395_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 535.0
TH2_k127_5621395_10 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008678 255.0
TH2_k127_5621395_11 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000007294 199.0
TH2_k127_5621395_12 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000001646 197.0
TH2_k127_5621395_13 alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000007947 190.0
TH2_k127_5621395_14 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000007665 151.0
TH2_k127_5621395_15 NUDIX domain - - - 0.000000000000000000000000000000000000001214 155.0
TH2_k127_5621395_16 carotenoid biosynthetic process K10212 - - 0.00000000000000000000000000000000001183 144.0
TH2_k127_5621395_17 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000002111 130.0
TH2_k127_5621395_18 PLD-like domain - - - 0.0000000000000000000000004436 111.0
TH2_k127_5621395_19 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588,K01945 - 5.4.99.18,6.3.4.13 0.00000000000000000000000953 101.0
TH2_k127_5621395_2 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 356.0
TH2_k127_5621395_20 methyltransferase activity - - - 0.0000000000000000000838 96.0
TH2_k127_5621395_21 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000001273 70.0
TH2_k127_5621395_22 - - - - 0.00000000006444 65.0
TH2_k127_5621395_23 - - - - 0.000000005262 59.0
TH2_k127_5621395_24 Ankyrin repeat domain protein - - - 0.00000001744 66.0
TH2_k127_5621395_25 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000008603 53.0
TH2_k127_5621395_3 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 338.0
TH2_k127_5621395_4 epimerase dehydratase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 340.0
TH2_k127_5621395_5 glycosyl transferase family 2 K10211 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 313.0
TH2_k127_5621395_6 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 302.0
TH2_k127_5621395_7 PFAM secretion protein HlyD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 300.0
TH2_k127_5621395_8 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 290.0
TH2_k127_5621395_9 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001873 285.0
TH2_k127_5621485_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 1.598e-255 812.0
TH2_k127_5621485_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 1.486e-217 686.0
TH2_k127_5621485_10 uncharacterised conserved protein UCP017998 - - - 0.000000000002032 78.0
TH2_k127_5621485_11 Protein of unknown function (DUF1722) - - - 0.00003017 46.0
TH2_k127_5621485_12 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0009923 43.0
TH2_k127_5621485_2 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 589.0
TH2_k127_5621485_3 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 425.0
TH2_k127_5621485_4 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 323.0
TH2_k127_5621485_5 coenzyme F420 binding K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000002355 181.0
TH2_k127_5621485_6 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000006005 137.0
TH2_k127_5621485_7 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000005439 129.0
TH2_k127_5621485_8 Protein of unknown function (DUF3243) - - - 0.0000000000000000000000000003053 115.0
TH2_k127_5635886_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 4.585e-298 931.0
TH2_k127_5635886_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 513.0
TH2_k127_5635886_2 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 493.0
TH2_k127_5635886_3 PFAM tRNA synthetase, class II (D, K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 393.0
TH2_k127_5635886_4 NAD(P)-binding Rossmann-like domain K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 331.0
TH2_k127_5635886_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 304.0
TH2_k127_5635886_6 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000004838 135.0
TH2_k127_5635886_7 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000282 84.0
TH2_k127_5635886_8 Lipopolysaccharide-assembly - - - 0.00000000001545 71.0
TH2_k127_5635886_9 nuclear chromosome segregation - - - 0.0000006745 57.0
TH2_k127_5648692_0 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 599.0
TH2_k127_5648692_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 441.0
TH2_k127_5648692_10 Protein of unknown function (DUF3096) - - - 0.0000003972 54.0
TH2_k127_5648692_11 - - - - 0.00002037 54.0
TH2_k127_5648692_2 KaiB K08481 - - 0.0000000000000000000000000000000000000000000009851 167.0
TH2_k127_5648692_3 KaiB K08481 - - 0.00000000000000000000000000000000001141 138.0
TH2_k127_5648692_5 PFAM Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000001976 109.0
TH2_k127_5648692_6 - - - - 0.0000000000000000002382 89.0
TH2_k127_5648692_7 Protein of unknown function (DUF3309) - - - 0.000000000000000004218 84.0
TH2_k127_5648692_8 - - - - 0.00000000000002491 74.0
TH2_k127_5648692_9 - - - - 0.00000002713 57.0
TH2_k127_5658384_0 PFAM nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 584.0
TH2_k127_5658384_1 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 535.0
TH2_k127_5658384_10 TraB family K00657,K09973 - 2.3.1.57 0.0000000000000000000000000000000000000000000000000000000000184 215.0
TH2_k127_5658384_11 DsrC like protein K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000004739 188.0
TH2_k127_5658384_12 Cysteine-rich domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000004053 159.0
TH2_k127_5658384_13 4Fe-4S dicluster domain - - - 0.00000000002331 74.0
TH2_k127_5658384_14 - - - - 0.0000000001664 63.0
TH2_k127_5658384_2 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 526.0
TH2_k127_5658384_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 473.0
TH2_k127_5658384_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 429.0
TH2_k127_5658384_5 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 379.0
TH2_k127_5658384_6 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 319.0
TH2_k127_5658384_7 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 299.0
TH2_k127_5658384_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002614 271.0
TH2_k127_5658384_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000978 243.0
TH2_k127_5661024_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 490.0
TH2_k127_5661024_1 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000006157 216.0
TH2_k127_5661024_2 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000000000004373 201.0
TH2_k127_5661024_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000006692 198.0
TH2_k127_5661024_4 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.0000000000000000000000000000000000000000000001481 183.0
TH2_k127_5661024_5 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000000000000000000000000000000004745 169.0
TH2_k127_5661024_6 - - - - 0.0001148 53.0
TH2_k127_5661372_0 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000000000000001452 179.0
TH2_k127_5661372_1 PIN domain - - - 0.00000000000000000000000000000000000000000000002301 174.0
TH2_k127_5661372_10 toxin-antitoxin pair type II binding K19159 - - 0.0002902 47.0
TH2_k127_5661372_11 PFAM VanZ - - - 0.0003227 52.0
TH2_k127_5661372_2 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000000000000000000000000003082 126.0
TH2_k127_5661372_3 sequence-specific DNA binding - - - 0.000000000000000000000000000001148 124.0
TH2_k127_5661372_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000004064 117.0
TH2_k127_5661372_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000007714 111.0
TH2_k127_5661372_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000001492 98.0
TH2_k127_5661372_7 Domain of unknown function (DUF1902) - - - 0.00000000000000000004097 91.0
TH2_k127_5661372_8 - - - - 0.00000000000001215 76.0
TH2_k127_5690950_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.558e-217 690.0
TH2_k127_5690950_1 Elongation factor Tu domain 2 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 619.0
TH2_k127_5690950_2 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 298.0
TH2_k127_5690950_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000004986 228.0
TH2_k127_5690950_4 PFAM Signal transduction histidine kinase, internal region - - - 0.00002796 54.0
TH2_k127_5702259_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 1.944e-320 987.0
TH2_k127_5702259_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 1.315e-263 827.0
TH2_k127_5702259_10 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000001051 91.0
TH2_k127_5702259_2 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 292.0
TH2_k127_5702259_3 Staphylopine dehydrogenase K04940 - 1.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000007721 274.0
TH2_k127_5702259_4 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003196 250.0
TH2_k127_5702259_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000005081 209.0
TH2_k127_5702259_6 PEGA domain - - - 0.000000000000000000001263 98.0
TH2_k127_570500_0 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002901 279.0
TH2_k127_570500_1 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000002041 231.0
TH2_k127_570500_2 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000000001409 169.0
TH2_k127_570500_3 LysE type translocator - - - 0.0000000000000000000000000000000001373 135.0
TH2_k127_570500_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000002153 119.0
TH2_k127_5751751_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003394 279.0
TH2_k127_5751751_1 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336 - 1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001974 270.0
TH2_k127_5751751_2 - - - - 0.00000000000000000000000001062 116.0
TH2_k127_5788184_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 473.0
TH2_k127_5788184_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002008 236.0
TH2_k127_5788184_2 Cysteine-rich domain - - - 0.000000000002794 70.0
TH2_k127_5790017_0 Alkylmercury lyase - - - 0.00000000000000001548 85.0
TH2_k127_5790017_2 Alkylmercury lyase - - - 0.000000005181 59.0
TH2_k127_5790017_4 PEP-CTERM motif - - - 0.00007541 53.0
TH2_k127_5801508_0 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 331.0
TH2_k127_5801508_1 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005251 267.0
TH2_k127_5801508_2 Multicopper oxidase K04753 - - 0.00000000000000000000000000000000002483 153.0
TH2_k127_5801508_3 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000001561 95.0
TH2_k127_5801508_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000002248 94.0
TH2_k127_5801508_5 - - - - 0.00000000000002009 77.0
TH2_k127_5801508_6 Transposase - - - 0.00000004443 58.0
TH2_k127_5801508_7 OsmC-like protein - - - 0.00000109 53.0
TH2_k127_5801508_8 PFAM Methyltransferase type 11 - - - 0.000001632 57.0
TH2_k127_5827250_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 519.0
TH2_k127_5827250_1 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 520.0
TH2_k127_5827250_10 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 353.0
TH2_k127_5827250_11 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 349.0
TH2_k127_5827250_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 342.0
TH2_k127_5827250_13 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 348.0
TH2_k127_5827250_14 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 327.0
TH2_k127_5827250_15 Alpha/beta hydrolase family K16050 - 3.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 310.0
TH2_k127_5827250_16 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000673 280.0
TH2_k127_5827250_17 PFAM metal-dependent phosphohydrolase HD sub - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005845 274.0
TH2_k127_5827250_18 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007293 259.0
TH2_k127_5827250_19 PFAM Oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000066 250.0
TH2_k127_5827250_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 507.0
TH2_k127_5827250_20 Bacterial extracellular solute-binding protein, family 7 K11688,K21395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002698 253.0
TH2_k127_5827250_21 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003142 254.0
TH2_k127_5827250_22 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000168 238.0
TH2_k127_5827250_23 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000001037 223.0
TH2_k127_5827250_24 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000006728 221.0
TH2_k127_5827250_25 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000002227 204.0
TH2_k127_5827250_26 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000002169 185.0
TH2_k127_5827250_27 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000004804 188.0
TH2_k127_5827250_28 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000002934 173.0
TH2_k127_5827250_29 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000003847 164.0
TH2_k127_5827250_3 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 479.0
TH2_k127_5827250_30 NMT1-like family K02051 - - 0.000000000000000000000000000000000000008885 157.0
TH2_k127_5827250_32 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000000000000008095 129.0
TH2_k127_5827250_33 - - - - 0.0000000000000000000000009062 117.0
TH2_k127_5827250_34 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000002942 109.0
TH2_k127_5827250_35 4Fe-4S binding domain - - - 0.0000000000000001637 82.0
TH2_k127_5827250_36 ATP-independent chaperone mediated protein folding K07803 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0008270,GO:0016151,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050897 - 0.000000000533 66.0
TH2_k127_5827250_37 - - - - 0.0008371 48.0
TH2_k127_5827250_4 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 467.0
TH2_k127_5827250_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009276 424.0
TH2_k127_5827250_6 cell adhesion involved in biofilm formation K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 392.0
TH2_k127_5827250_7 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 392.0
TH2_k127_5827250_8 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 372.0
TH2_k127_5827250_9 PFAM Prokaryotic protein of K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 360.0
TH2_k127_5841103_0 Belongs to the aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 347.0
TH2_k127_5841103_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 313.0
TH2_k127_5841103_2 ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006234 274.0
TH2_k127_5841103_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002812 267.0
TH2_k127_5841103_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000141 263.0
TH2_k127_5841103_5 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003087 259.0
TH2_k127_5841103_6 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001066 258.0
TH2_k127_5841103_7 FCD K05799 - - 0.000000000000000000000000000000000000000000000000000000213 203.0
TH2_k127_5841103_8 - - - - 0.000000000000000000000000000000000000000000000000003553 183.0
TH2_k127_5841103_9 Haem-degrading K11477 - - 0.00000000000000000000000000001732 123.0
TH2_k127_5842488_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 426.0
TH2_k127_58923_0 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 472.0
TH2_k127_58923_1 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 376.0
TH2_k127_58923_10 Chlorite dismutase - - - 0.00000000000000000000000001004 111.0
TH2_k127_58923_11 glucan 1,4-alpha-glucosidase activity K05989,K20541 - 3.2.1.40 0.000000000000001134 89.0
TH2_k127_58923_12 LuxR family transcriptional regulator K07696 - - 0.0000000165 59.0
TH2_k127_58923_13 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000002186 62.0
TH2_k127_58923_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 370.0
TH2_k127_58923_3 PFAM MltA K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 345.0
TH2_k127_58923_4 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001235 293.0
TH2_k127_58923_5 Pyruvate kinase, alpha/beta domain K09126 - - 0.0000000000000000000000000000000000000000000000000000000000006325 216.0
TH2_k127_58923_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 0.000000000000000000000000000000000000002229 153.0
TH2_k127_58923_7 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000001277 157.0
TH2_k127_58923_8 Protein tyrosine serine phosphatase - - - 0.000000000000000000000000000000001398 143.0
TH2_k127_58923_9 OprF membrane domain K03286 - - 0.00000000000000000000000000007038 121.0
TH2_k127_59018_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 2.32e-246 785.0
TH2_k127_59018_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 380.0
TH2_k127_59018_2 acetoacetate decarboxylase K01574 - 4.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 291.0
TH2_k127_5948744_0 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 404.0
TH2_k127_5948744_1 PFAM Integrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 400.0
TH2_k127_5948744_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 336.0
TH2_k127_5948744_3 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 293.0
TH2_k127_5948744_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009435 296.0
TH2_k127_5948744_5 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000005449 175.0
TH2_k127_5948744_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000001196 124.0
TH2_k127_5948744_7 Alpha amylase, catalytic domain - - - 0.000000000000000001799 85.0
TH2_k127_5957131_0 hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 499.0
TH2_k127_5957131_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 487.0
TH2_k127_5957131_2 haemagglutination activity domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 394.0
TH2_k127_5957131_3 dextransucrase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001089 256.0
TH2_k127_5957131_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.0000000000000000000000000000000000001046 152.0
TH2_k127_596077_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.269e-286 897.0
TH2_k127_596077_1 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 525.0
TH2_k127_596077_10 - - - - 0.000000000000000000006171 98.0
TH2_k127_596077_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000003093 89.0
TH2_k127_596077_12 Helix-turn-helix - - - 0.000000006498 63.0
TH2_k127_596077_13 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000001411 56.0
TH2_k127_596077_14 - - - - 0.0000001918 55.0
TH2_k127_596077_2 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 417.0
TH2_k127_596077_3 2-Keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 335.0
TH2_k127_596077_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 313.0
TH2_k127_596077_5 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002234 287.0
TH2_k127_596077_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001833 267.0
TH2_k127_596077_7 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001178 250.0
TH2_k127_596077_8 - - - - 0.000000000000000000000000000000000000000000000000002041 185.0
TH2_k127_596077_9 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000000000000001251 147.0
TH2_k127_59758_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.76e-277 863.0
TH2_k127_59758_1 GTP-binding protein TypA K06207 - - 1.349e-259 812.0
TH2_k127_59758_10 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 301.0
TH2_k127_59758_11 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 294.0
TH2_k127_59758_12 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.0000000000000000000000000000000000000000000000000000000000002251 219.0
TH2_k127_59758_13 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000002533 183.0
TH2_k127_59758_14 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000007809 184.0
TH2_k127_59758_15 thioredoxin peroxidase activity K11065 - 1.11.1.15 0.000000000000000000000000000000000000000006418 162.0
TH2_k127_59758_16 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000004285 146.0
TH2_k127_59758_17 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000005907 142.0
TH2_k127_59758_18 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000006721 123.0
TH2_k127_59758_19 Protein of unknown function (DUF3617) - - - 0.000000000000000000000000003339 116.0
TH2_k127_59758_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.81e-233 732.0
TH2_k127_59758_20 Toxic component of a type II toxin-antitoxin (TA) system. A sequence-specific mRNA endoribonuclease that inhibits translation elongation and induces bacterial stasis. Cleavage occurs between the second and third residue of the Lys codon followed by a G or A (5'AAA(G A)3'), is reading-frame dependent and occurs within the 5' end of most mRNAs. Ribosome-binding confers the sequence specificity and reading frame-dependence. When overexpressed in liquid media YafQ partially inhibits protein synthesis, with a reduction in growth rate and colony growth rate. This effect is counteracted by coexpression with cognate antitoxin DinJ. YafQ and DinJ together bind their own promoter, and repress its expression K19157 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006415,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032984,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034655,GO:0042221,GO:0042710,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043565,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044010,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044764,GO:0044877,GO:0046483,GO:0046677,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 - 0.000000000000000000000000512 110.0
TH2_k127_59758_21 Competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.0000000000000000001598 97.0
TH2_k127_59758_22 RelB antitoxin K07473 - - 0.00000000000000003386 83.0
TH2_k127_59758_23 Phospholipase D. Active site motifs. - - - 0.00000001854 57.0
TH2_k127_59758_24 - - - - 0.0000002526 55.0
TH2_k127_59758_26 Predicted membrane protein (DUF2231) - - - 0.0002263 49.0
TH2_k127_59758_27 response regulator - - - 0.0002432 50.0
TH2_k127_59758_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.576e-200 632.0
TH2_k127_59758_4 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 562.0
TH2_k127_59758_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 491.0
TH2_k127_59758_6 involved in lipopolysaccharide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 481.0
TH2_k127_59758_7 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 426.0
TH2_k127_59758_8 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 368.0
TH2_k127_59758_9 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 307.0
TH2_k127_6006285_0 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 320.0
TH2_k127_6007717_0 Multicopper oxidase K06324 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 535.0
TH2_k127_6007717_1 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 477.0
TH2_k127_6007717_10 NosL - - - 0.00000000000000000000000000000000000000000000000001737 184.0
TH2_k127_6007717_11 NosL - - - 0.00000000000000000000000000000000000000000000000009328 188.0
TH2_k127_6007717_12 NosL - - - 0.000000000000000000000000000000000000001231 159.0
TH2_k127_6007717_13 Transposase - - - 0.00000000000000000000000000000000003057 140.0
TH2_k127_6007717_14 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000002147 131.0
TH2_k127_6007717_15 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000000000214 148.0
TH2_k127_6007717_16 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000001678 114.0
TH2_k127_6007717_17 - - - - 0.0000000000000000000000004827 108.0
TH2_k127_6007717_18 transferase activity, transferring glycosyl groups - - - 0.0000000000000000001326 89.0
TH2_k127_6007717_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000001142 98.0
TH2_k127_6007717_2 PFAM transposase IS4 family protein K07481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 473.0
TH2_k127_6007717_20 YtkA-like - - - 0.000000000001309 72.0
TH2_k127_6007717_21 YtkA-like - - - 0.000000000002005 74.0
TH2_k127_6007717_23 cellulase activity - - - 0.0001188 56.0
TH2_k127_6007717_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 387.0
TH2_k127_6007717_4 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 330.0
TH2_k127_6007717_5 dextransucrase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008076 288.0
TH2_k127_6007717_6 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006037 244.0
TH2_k127_6007717_7 NosL - - - 0.000000000000000000000000000000000000000000000000000000000000005038 220.0
TH2_k127_6007717_8 Multicopper oxidase K04753 - - 0.0000000000000000000000000000000000000000000000000000000000004104 242.0
TH2_k127_6007717_9 NosL - - - 0.00000000000000000000000000000000000000000000000000000002076 201.0
TH2_k127_6009914_0 glycosyl transferase, family 39 - - - 0.0000000000006433 81.0
TH2_k127_6009960_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 607.0
TH2_k127_6009960_1 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 381.0
TH2_k127_6009960_2 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000967 65.0
TH2_k127_6014619_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003895 278.0
TH2_k127_6014619_1 sequence-specific DNA binding K18830 - - 0.000000000000000000000000000000000000000000000008826 173.0
TH2_k127_6014619_2 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000001876 190.0
TH2_k127_6014619_4 - - - - 0.000000000002482 78.0
TH2_k127_6019641_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.392e-244 773.0
TH2_k127_6019641_1 Family membership - - - 4.092e-202 671.0
TH2_k127_6019641_10 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000000000000000006825 126.0
TH2_k127_6019641_11 cell division protein FtsL - - - 0.0000000000001919 74.0
TH2_k127_6019641_12 tetratricopeptide repeat - - - 0.000002493 59.0
TH2_k127_6019641_2 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 4.008e-194 626.0
TH2_k127_6019641_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 484.0
TH2_k127_6019641_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 405.0
TH2_k127_6019641_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 378.0
TH2_k127_6019641_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000001043 273.0
TH2_k127_6019641_7 Domain of unknown function (DUF1287) K09974 - - 0.00000000000000000000000000000000000000000000000000000000000000001543 229.0
TH2_k127_6019641_8 transcription regulator activity K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000005335 161.0
TH2_k127_6019641_9 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000000000008566 149.0
TH2_k127_6026763_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.7e-321 993.0
TH2_k127_6026763_1 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 517.0
TH2_k127_6026763_10 Receptor family ligand binding region K01999 - - 0.0000000001706 73.0
TH2_k127_6026763_2 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 445.0
TH2_k127_6026763_3 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 436.0
TH2_k127_6026763_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 433.0
TH2_k127_6026763_5 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 420.0
TH2_k127_6026763_6 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 396.0
TH2_k127_6026763_7 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 306.0
TH2_k127_6026763_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000001856 147.0
TH2_k127_6026763_9 Archaebacterial flagellin - - - 0.000000000000003407 83.0
TH2_k127_605482_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 2.372e-269 849.0
TH2_k127_605482_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K20449 - 1.3.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 615.0
TH2_k127_605482_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 379.0
TH2_k127_605482_11 Amino acid synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 295.0
TH2_k127_605482_12 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003442 280.0
TH2_k127_605482_13 Allophanate hydrolase subunit 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001233 271.0
TH2_k127_605482_14 PFAM Short-chain dehydrogenase reductase SDR K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000003644 265.0
TH2_k127_605482_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000891 263.0
TH2_k127_605482_16 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007064 259.0
TH2_k127_605482_17 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000009063 256.0
TH2_k127_605482_18 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001189 256.0
TH2_k127_605482_19 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007452 250.0
TH2_k127_605482_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 535.0
TH2_k127_605482_20 short-chain K00034,K00038,K00046 - 1.1.1.47,1.1.1.53,1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000001166 233.0
TH2_k127_605482_21 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000313 225.0
TH2_k127_605482_22 xanthine dehydrogenase activity K03519,K13479,K20445 - 1.17.1.4,1.17.1.5,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000001339 223.0
TH2_k127_605482_23 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000000000000000003624 215.0
TH2_k127_605482_24 - K01992,K19341 - - 0.000000000000000000000000000000000000000000000000000000000000392 221.0
TH2_k127_605482_25 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001911 206.0
TH2_k127_605482_26 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K09740 - - 0.00000000000000000000000000000000000000000000000000001112 200.0
TH2_k127_605482_27 Transcriptional regulator IclR - - - 0.000000000000000000000000000000000000000000000000001059 192.0
TH2_k127_605482_28 Pfam:AHS1 K06351 - - 0.0000000000000000000000000000000000000000000000004775 184.0
TH2_k127_605482_29 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000919 133.0
TH2_k127_605482_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 517.0
TH2_k127_605482_30 Amidohydrolase K07045 - - 0.00000000000000000000000000000001887 136.0
TH2_k127_605482_31 urea carboxylase-associated protein 1 K09967 - - 0.000000000000000000000000002527 119.0
TH2_k127_605482_33 - - - - 0.00000000000000000002069 100.0
TH2_k127_605482_34 TonB C terminal K03832 - - 0.0000000000000000001205 100.0
TH2_k127_605482_35 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000001803 58.0
TH2_k127_605482_36 - - - - 0.0002708 49.0
TH2_k127_605482_37 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0009522 42.0
TH2_k127_605482_4 Amidohydrolase family K15358 - 3.5.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 513.0
TH2_k127_605482_5 peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 488.0
TH2_k127_605482_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 483.0
TH2_k127_605482_7 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 428.0
TH2_k127_605482_8 Psort location Cytoplasmic, score 8.87 K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 398.0
TH2_k127_605482_9 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 392.0
TH2_k127_61052_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.973e-225 705.0
TH2_k127_61052_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 514.0
TH2_k127_61052_10 - - - - 0.00000000005325 70.0
TH2_k127_61052_11 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000002263 57.0
TH2_k127_61052_13 HEAT repeat - - - 0.0000002183 61.0
TH2_k127_61052_14 - - - - 0.000002612 57.0
TH2_k127_61052_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 395.0
TH2_k127_61052_3 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 297.0
TH2_k127_61052_4 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000005523 225.0
TH2_k127_61052_5 PFAM Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000005974 218.0
TH2_k127_61052_6 - - - - 0.00000000000000000000000000000000001785 137.0
TH2_k127_61052_7 O-methyltransferase - - - 0.000000000000000000000000000000003716 138.0
TH2_k127_61052_8 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000007664 110.0
TH2_k127_61052_9 RNA-binding protein - - - 0.00000000000000000000005642 101.0
TH2_k127_6123402_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1024.0
TH2_k127_6123402_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.695e-321 1000.0
TH2_k127_6123402_10 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001269 278.0
TH2_k127_6123402_11 branched-chain amino acid K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002904 249.0
TH2_k127_6123402_12 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000002302 209.0
TH2_k127_6123402_13 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000002713 217.0
TH2_k127_6123402_14 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000001229 195.0
TH2_k127_6123402_15 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000009337 190.0
TH2_k127_6123402_16 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000003356 186.0
TH2_k127_6123402_17 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000004114 181.0
TH2_k127_6123402_18 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000000000000000000000000000000000001108 163.0
TH2_k127_6123402_19 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000000006109 147.0
TH2_k127_6123402_2 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 2.226e-231 729.0
TH2_k127_6123402_20 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000001473 150.0
TH2_k127_6123402_21 PIN domain K19686 - - 0.00000000000000000000000000000007025 129.0
TH2_k127_6123402_22 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000001618 110.0
TH2_k127_6123402_23 - - - - 0.0000000000000000058 89.0
TH2_k127_6123402_24 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000000000006347 86.0
TH2_k127_6123402_25 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.0000000000000261 74.0
TH2_k127_6123402_26 YsiA-like protein, C-terminal region K13770 - - 0.000000003511 60.0
TH2_k127_6123402_28 toxin-antitoxin pair type II binding - - - 0.000001624 53.0
TH2_k127_6123402_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 5.096e-231 734.0
TH2_k127_6123402_30 Bacterial regulatory proteins TetR family - - - 0.0002197 47.0
TH2_k127_6123402_4 Ftsk_gamma K03466 - - 8.219e-226 721.0
TH2_k127_6123402_5 PFAM glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 502.0
TH2_k127_6123402_6 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 374.0
TH2_k127_6123402_7 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 314.0
TH2_k127_6123402_8 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 321.0
TH2_k127_6123402_9 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 319.0
TH2_k127_613436_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 518.0
TH2_k127_613436_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 435.0
TH2_k127_613436_10 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000003065 64.0
TH2_k127_613436_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 326.0
TH2_k127_613436_3 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 294.0
TH2_k127_613436_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000001832 235.0
TH2_k127_613436_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002336 228.0
TH2_k127_613436_6 alcohol dehydrogenase K00043 - 1.1.1.61 0.0000000000000000000000000000000000000000000000000000000000001279 241.0
TH2_k127_613436_7 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000008138 160.0
TH2_k127_613436_8 - - - - 0.00000000000000000000002925 105.0
TH2_k127_6151391_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.694e-246 773.0
TH2_k127_6151391_1 PAS domain K13598 - 2.7.13.3 1.707e-226 723.0
TH2_k127_6151391_10 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 420.0
TH2_k127_6151391_11 2-Hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 393.0
TH2_k127_6151391_12 to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 326.0
TH2_k127_6151391_13 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 319.0
TH2_k127_6151391_14 PFAM TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 331.0
TH2_k127_6151391_15 PFAM import inner membrane translocase, subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 309.0
TH2_k127_6151391_16 ATPases associated with a variety of cellular activities K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 292.0
TH2_k127_6151391_17 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006193 242.0
TH2_k127_6151391_18 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000000000000000000001821 243.0
TH2_k127_6151391_19 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000096 221.0
TH2_k127_6151391_2 Protein of unknown function, DUF255 K06888 - - 4.565e-223 710.0
TH2_k127_6151391_20 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000002205 210.0
TH2_k127_6151391_21 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000002076 200.0
TH2_k127_6151391_22 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000002442 201.0
TH2_k127_6151391_23 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000045 204.0
TH2_k127_6151391_24 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000000000000000002208 183.0
TH2_k127_6151391_25 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000002166 159.0
TH2_k127_6151391_26 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000002022 159.0
TH2_k127_6151391_27 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000001449 151.0
TH2_k127_6151391_28 - - - - 0.0000000000000000000000000000000004234 136.0
TH2_k127_6151391_29 Reverse transcriptase-like K03469 - 3.1.26.4 0.0000000000000000000000000000000009869 135.0
TH2_k127_6151391_3 Belongs to the aldehyde dehydrogenase family - - - 4.465e-219 689.0
TH2_k127_6151391_30 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000001572 123.0
TH2_k127_6151391_31 ACT domain - - - 0.0000000000000000000000000003021 121.0
TH2_k127_6151391_32 Belongs to the Fur family K03711 - - 0.00000000000000000000000141 108.0
TH2_k127_6151391_33 GIY-YIG catalytic domain - - - 0.000000000000000000000003755 104.0
TH2_k127_6151391_34 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000003616 97.0
TH2_k127_6151391_35 Alkylmercury lyase - - - 0.00000000000000000001614 93.0
TH2_k127_6151391_36 - - - - 0.000000000000000002091 93.0
TH2_k127_6151391_38 SpoVT / AbrB like domain K07172 - - 0.00000000000001348 77.0
TH2_k127_6151391_4 Exodeoxyribonuclease V, gamma subunit K03657 - 3.6.4.12 3.19e-207 667.0
TH2_k127_6151391_40 Alkylmercury lyase - - - 0.000000000405 62.0
TH2_k127_6151391_42 protein ExbD TolR K03559 - - 0.00000008932 59.0
TH2_k127_6151391_43 Cobalt transport protein K02008 - - 0.0001124 53.0
TH2_k127_6151391_44 - - - - 0.0002223 43.0
TH2_k127_6151391_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.585e-197 632.0
TH2_k127_6151391_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 485.0
TH2_k127_6151391_7 ATPase domain of DNA mismatch repair MUTS family K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 485.0
TH2_k127_6151391_8 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 453.0
TH2_k127_6151391_9 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 417.0
TH2_k127_617439_0 carbon starvation protein CstA K06200 - - 2.308e-283 878.0
TH2_k127_617439_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 574.0
TH2_k127_617439_2 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 294.0
TH2_k127_617439_3 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000000001589 187.0
TH2_k127_617439_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000001238 183.0
TH2_k127_617439_5 - - - - 0.00000000000000000000000000000000000000000001714 162.0
TH2_k127_617439_6 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000001173 158.0
TH2_k127_617439_7 - - - - 0.00000002635 58.0
TH2_k127_6181326_0 formate C-acetyltransferase glycine radical - - - 1.002e-306 965.0
TH2_k127_6181326_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 7.859e-284 889.0
TH2_k127_6181326_10 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 372.0
TH2_k127_6181326_11 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 353.0
TH2_k127_6181326_12 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 317.0
TH2_k127_6181326_13 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 314.0
TH2_k127_6181326_14 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 312.0
TH2_k127_6181326_15 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 303.0
TH2_k127_6181326_16 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 302.0
TH2_k127_6181326_17 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002424 290.0
TH2_k127_6181326_18 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000002174 224.0
TH2_k127_6181326_19 - - - - 0.000000000000000000000000000000000000000000000000000000000001288 220.0
TH2_k127_6181326_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 8.867e-260 833.0
TH2_k127_6181326_20 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000034 220.0
TH2_k127_6181326_21 Ribosomal protein L11 methyltransferase (PrmA) K15460 - 2.1.1.223 0.000000000000000000000000000000000000000000000000000000000005926 216.0
TH2_k127_6181326_22 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000004076 215.0
TH2_k127_6181326_24 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000007855 161.0
TH2_k127_6181326_25 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18990 - - 0.000000000000000000000000000000000000000001767 170.0
TH2_k127_6181326_26 - - - - 0.00000000000000000000000000000000000000004385 158.0
TH2_k127_6181326_27 Thioredoxin-like - - - 0.00000000000000000000000000000004972 131.0
TH2_k127_6181326_28 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000008688 129.0
TH2_k127_6181326_29 Lysin motif - - - 0.000000000000000000000000000001236 132.0
TH2_k127_6181326_3 DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 565.0
TH2_k127_6181326_31 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000003135 127.0
TH2_k127_6181326_32 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000009984 123.0
TH2_k127_6181326_33 Protein of unknown function, DUF488 - - - 0.000000000000000000000002502 106.0
TH2_k127_6181326_34 phosphorelay signal transduction system K07658 - - 0.00000000000000000000004336 103.0
TH2_k127_6181326_35 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000002043 87.0
TH2_k127_6181326_36 Tetratricopeptide repeat - - - 0.000000000000000002732 96.0
TH2_k127_6181326_37 sodium-dependent phosphate transmembrane transporter activity - - - 0.000000000000000226 87.0
TH2_k127_6181326_38 B-1 B cell differentiation - - - 0.0000000001244 62.0
TH2_k127_6181326_39 PFAM peptidase - - - 0.000001061 57.0
TH2_k127_6181326_4 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 527.0
TH2_k127_6181326_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 517.0
TH2_k127_6181326_6 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 480.0
TH2_k127_6181326_7 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 467.0
TH2_k127_6181326_8 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 445.0
TH2_k127_6181326_9 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 434.0
TH2_k127_6186765_0 AMP-binding enzyme C-terminal domain - - - 2.114e-288 891.0
TH2_k127_6186765_1 methionyl-tRNA aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.952e-207 657.0
TH2_k127_6186765_10 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 301.0
TH2_k127_6186765_11 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000159 278.0
TH2_k127_6186765_12 reductase K00059,K07535,K22251 - 1.1.1.100,1.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000446 271.0
TH2_k127_6186765_13 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001167 266.0
TH2_k127_6186765_14 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002282 257.0
TH2_k127_6186765_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001768 252.0
TH2_k127_6186765_16 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001975 229.0
TH2_k127_6186765_17 Enoyl-(Acyl carrier protein) reductase K03366 - 1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000000007271 225.0
TH2_k127_6186765_18 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000001634 218.0
TH2_k127_6186765_19 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000006322 217.0
TH2_k127_6186765_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 528.0
TH2_k127_6186765_20 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000001076 155.0
TH2_k127_6186765_22 Belongs to the bacterial histone-like protein family K05788 - - 0.000000000000000000000000000002928 123.0
TH2_k127_6186765_23 Protein of unknown function (DUF721) - - - 0.00000000000000001381 88.0
TH2_k127_6186765_24 PFAM Class III cytochrome C family - - - 0.000000000000001567 81.0
TH2_k127_6186765_25 bacterial-type flagellum-dependent cell motility - - - 0.00000000001114 70.0
TH2_k127_6186765_26 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000001312 58.0
TH2_k127_6186765_27 Helix-turn-helix domain - - - 0.00003749 48.0
TH2_k127_6186765_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 420.0
TH2_k127_6186765_4 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 406.0
TH2_k127_6186765_5 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 341.0
TH2_k127_6186765_6 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 340.0
TH2_k127_6186765_7 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 346.0
TH2_k127_6186765_8 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 335.0
TH2_k127_6186765_9 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 317.0
TH2_k127_619731_0 dEAD DEAH box helicase K06877 - - 2.424e-297 932.0
TH2_k127_619731_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001138 232.0
TH2_k127_619731_2 RNase_H superfamily K07502 - - 0.000000000000000127 85.0
TH2_k127_6213260_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.039e-239 757.0
TH2_k127_6213260_1 TIGRFAM formate dehydrogenase, alpha subunit K00336,K05299 - 1.17.1.10,1.6.5.3 1.773e-227 732.0
TH2_k127_6213260_10 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 337.0
TH2_k127_6213260_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001348 199.0
TH2_k127_6213260_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000003895 177.0
TH2_k127_6213260_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K00338 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000001954 157.0
TH2_k127_6213260_14 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000000003232 145.0
TH2_k127_6213260_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000009574 124.0
TH2_k127_6213260_16 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000008197 124.0
TH2_k127_6213260_17 phosphorelay signal transduction system - - - 0.00000000000000000000000000003952 122.0
TH2_k127_6213260_18 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000003253 59.0
TH2_k127_6213260_19 Transcription regulator of the Arc MetJ class - - - 0.000000006253 60.0
TH2_k127_6213260_2 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 4.624e-216 688.0
TH2_k127_6213260_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000194 46.0
TH2_k127_6213260_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 3.351e-206 653.0
TH2_k127_6213260_4 PFAM formate nitrite transporter K06212,K21993 - - 4.507e-197 621.0
TH2_k127_6213260_5 Pyridine nucleotide-disulphide oxidoreductase K15022 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.17.1.10 9.813e-195 628.0
TH2_k127_6213260_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 541.0
TH2_k127_6213260_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 535.0
TH2_k127_6213260_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 370.0
TH2_k127_6213260_9 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 347.0
TH2_k127_6214258_0 Belongs to the enoyl-CoA hydratase isomerase family K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 6.627e-233 738.0
TH2_k127_6214258_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 591.0
TH2_k127_6215981_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1061.0
TH2_k127_6215981_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.661e-239 755.0
TH2_k127_6215981_10 4Fe-4S binding domain K02572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 533.0
TH2_k127_6215981_11 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 475.0
TH2_k127_6215981_12 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 475.0
TH2_k127_6215981_13 PFAM transposase IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 442.0
TH2_k127_6215981_14 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 442.0
TH2_k127_6215981_15 DeoC/LacD family aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 426.0
TH2_k127_6215981_16 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 339.0
TH2_k127_6215981_17 Aldo/keto reductase family K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 322.0
TH2_k127_6215981_18 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 302.0
TH2_k127_6215981_19 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000005871 264.0
TH2_k127_6215981_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.938e-223 703.0
TH2_k127_6215981_20 ANTAR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001407 251.0
TH2_k127_6215981_21 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000959 240.0
TH2_k127_6215981_22 Glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000000000000000000000000000000000879 233.0
TH2_k127_6215981_23 Pfam:DUF162 - - - 0.00000000000000000000000000000000000000000000000000000000000008773 220.0
TH2_k127_6215981_24 - - - - 0.000000000000000000000000000000000000000000000000000004953 201.0
TH2_k127_6215981_25 Histidine kinase K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000003094 209.0
TH2_k127_6215981_26 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000001637 186.0
TH2_k127_6215981_27 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000001017 154.0
TH2_k127_6215981_28 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000001717 159.0
TH2_k127_6215981_29 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000001303 140.0
TH2_k127_6215981_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 2.117e-217 688.0
TH2_k127_6215981_30 - - - - 0.000000000000000000000000000003016 124.0
TH2_k127_6215981_31 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.000000000000000000000000003456 118.0
TH2_k127_6215981_32 nucleotidyltransferase activity K00984,K19279 - 2.7.7.47 0.00000000000000000000000002442 113.0
TH2_k127_6215981_33 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000008507 76.0
TH2_k127_6215981_34 Type II secretion system protein B K02451 - - 0.0000000001343 71.0
TH2_k127_6215981_35 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02584 - - 0.0000000002398 70.0
TH2_k127_6215981_36 Protein of unknown function DUF86 - - - 0.000002063 53.0
TH2_k127_6215981_37 Protein of unknown function DUF86 - - - 0.000005121 49.0
TH2_k127_6215981_38 SMART Chromosomal replication initiator DnaA domain - - - 0.00000698 50.0
TH2_k127_6215981_39 Bacterial regulatory protein, Fis family K07712 - - 0.00003952 54.0
TH2_k127_6215981_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 2.482e-205 645.0
TH2_k127_6215981_5 Ammonium Transporter Family K03320 - - 1.663e-202 638.0
TH2_k127_6215981_6 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 1.051e-201 636.0
TH2_k127_6215981_7 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 589.0
TH2_k127_6215981_8 PFAM isocitrate isopropylmalate dehydrogenase K00052,K07246 - 1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 545.0
TH2_k127_6215981_9 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 555.0
TH2_k127_6244895_0 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000001174 220.0
TH2_k127_6244895_1 bis(5'-adenosyl)-triphosphatase activity K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.00000000000000000000000000000000000000000000000000006869 191.0
TH2_k127_6244895_2 - - - - 0.000005885 53.0
TH2_k127_6244895_4 PilZ domain - - - 0.00004545 51.0
TH2_k127_6244895_5 PilZ domain - - - 0.0006441 47.0
TH2_k127_6291660_0 PFAM Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 402.0
TH2_k127_6291660_1 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001102 267.0
TH2_k127_6291660_2 AAA domain K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006337 243.0
TH2_k127_6291660_3 Transposase, Mutator family - - - 0.0006651 42.0
TH2_k127_6336830_0 Semialdehyde dehydrogenase, NAD binding domain K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 423.0
TH2_k127_6336830_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002253 285.0
TH2_k127_6336830_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008034 284.0
TH2_k127_6336830_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000008402 206.0
TH2_k127_6336830_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000001743 167.0
TH2_k127_6336830_5 Cytochrome C' - - - 0.00000000000000000000000006619 112.0
TH2_k127_6336830_6 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000002533 89.0
TH2_k127_633989_0 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002904 282.0
TH2_k127_633989_1 Histidine kinase HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009876 293.0
TH2_k127_633989_2 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000001885 126.0
TH2_k127_633989_3 sequence-specific DNA binding - - - 0.0001663 48.0
TH2_k127_6407084_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 6.395e-260 810.0
TH2_k127_6407084_1 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01847,K01848 - 5.4.99.2 2.172e-229 722.0
TH2_k127_6407084_10 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 331.0
TH2_k127_6407084_11 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000004883 218.0
TH2_k127_6407084_12 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000001799 208.0
TH2_k127_6407084_13 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000001015 204.0
TH2_k127_6407084_14 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000009569 187.0
TH2_k127_6407084_15 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000009703 172.0
TH2_k127_6407084_16 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000003746 164.0
TH2_k127_6407084_17 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00000000000000000000000000000000000000009253 158.0
TH2_k127_6407084_18 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000003306 136.0
TH2_k127_6407084_19 4Fe-4S dicluster domain - - - 0.000000000000000001413 90.0
TH2_k127_6407084_2 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 2.105e-227 715.0
TH2_k127_6407084_20 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000001986 83.0
TH2_k127_6407084_21 - - - - 0.0000000000000006124 79.0
TH2_k127_6407084_3 acyl-coa dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 601.0
TH2_k127_6407084_4 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 606.0
TH2_k127_6407084_5 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 590.0
TH2_k127_6407084_6 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 515.0
TH2_k127_6407084_7 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 392.0
TH2_k127_6407084_8 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 383.0
TH2_k127_6407084_9 PFAM Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 338.0
TH2_k127_6411455_0 ATP-grasp domain K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 603.0
TH2_k127_6411455_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 604.0
TH2_k127_6411455_2 CoA-ligase K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 484.0
TH2_k127_6411455_3 ORF6N domain - - - 0.0000000000000000000000000000000000000000000000001065 183.0
TH2_k127_6411455_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000000000000007659 145.0
TH2_k127_6411455_5 PIN domain - - - 0.0000000005973 66.0
TH2_k127_6411455_6 regulation of single-species biofilm formation - - - 0.000000001992 60.0
TH2_k127_6411455_7 - - - - 0.000000457 55.0
TH2_k127_6411455_8 adenylate kinase activity - - - 0.0006046 45.0
TH2_k127_6411455_9 Endonuclease related to archaeal Holliday junction resolvase - - - 0.0006968 44.0
TH2_k127_6475987_0 BadF BadG BcrA BcrD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009156 400.0
TH2_k127_6475987_1 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 292.0
TH2_k127_6475987_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001477 263.0
TH2_k127_6475987_3 PFAM Nitroreductase family - - - 0.00000000000000000000000000000000000000000000008883 172.0
TH2_k127_6475987_4 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000000000000000001212 159.0
TH2_k127_6475987_5 SEC-C motif - - - 0.0000000000000000000000000000001317 140.0
TH2_k127_6475987_6 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - 0.000000000000000000000000000005805 122.0
TH2_k127_6475987_7 - - - - 0.00000000001082 68.0
TH2_k127_6509691_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 536.0
TH2_k127_6509691_1 Penicillin amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 377.0
TH2_k127_6509691_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000799 286.0
TH2_k127_6509691_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000002445 77.0
TH2_k127_6509691_5 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000001855 72.0
TH2_k127_6509691_6 reverse transcriptase - - - 0.000000048 55.0
TH2_k127_6509691_7 - - - - 0.0000007485 55.0
TH2_k127_6532155_0 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 626.0
TH2_k127_6532155_1 glycosyl transferase family 39 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 312.0
TH2_k127_6532155_2 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 282.0
TH2_k127_6532155_3 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000006474 256.0
TH2_k127_6532155_4 PFAM Lipid A Biosynthesis N-terminal - - - 0.00000000000000000000000000001359 121.0
TH2_k127_6532155_5 Phospholipid methyltransferase - - - 0.00000000000000000000000011 113.0
TH2_k127_6532155_6 serine threonine protein kinase - - - 0.0000000000000000000000003025 113.0
TH2_k127_6532155_7 Uncharacterized protein family UPF0054 K07042 - - 0.000000000000000000000279 102.0
TH2_k127_6532155_8 kinase activity - - - 0.00000000000000000001342 99.0
TH2_k127_6553479_0 Aminotransferase class-III K00833,K03851,K12256,K15372 - 2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77 1.557e-204 644.0
TH2_k127_6553479_1 alcohol dehydrogenase K19954 - - 0.0000000000000000000000000000000000000000000000002215 180.0
TH2_k127_6553479_2 Helix-turn-helix XRE-family like proteins - - - 0.0002009 46.0
TH2_k127_6563864_0 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 404.0
TH2_k127_6563864_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 298.0
TH2_k127_6563864_10 PFAM S23 ribosomal protein - - - 0.00000839 48.0
TH2_k127_6563864_11 23S rRNA-intervening sequence protein - - - 0.0001172 44.0
TH2_k127_6563864_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 319.0
TH2_k127_6563864_3 cyclic-guanylate-specific phosphodiesterase activity - - - 0.00000000000000000000000000000000000000001972 175.0
TH2_k127_6563864_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000001711 134.0
TH2_k127_6563864_5 HD domain - - - 0.000000000000000000000000000000002344 142.0
TH2_k127_6563864_6 PFAM response regulator receiver - - - 0.000000000000000000000000000002803 123.0
TH2_k127_6563864_7 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000002948 102.0
TH2_k127_6563864_8 PFAM S23 ribosomal protein - - - 0.000000001173 62.0
TH2_k127_6563864_9 - - - - 0.0000007346 55.0
TH2_k127_6595425_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 483.0
TH2_k127_6595425_1 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 312.0
TH2_k127_6595425_2 Trypsin - - - 0.00000000000000000000000002076 111.0
TH2_k127_6630600_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 546.0
TH2_k127_6630600_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 334.0
TH2_k127_6630600_2 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 312.0
TH2_k127_6630600_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002477 264.0
TH2_k127_6634571_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 472.0
TH2_k127_6634571_1 acyl-coa dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 436.0
TH2_k127_6634571_2 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 424.0
TH2_k127_6634571_3 lactate metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 396.0
TH2_k127_6634571_4 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000001692 173.0
TH2_k127_6634571_5 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000001511 163.0
TH2_k127_6634571_6 Transcription regulator MerR DNA binding K21902 - - 0.00000000000000000000000000000000000001532 149.0
TH2_k127_6634571_7 DRTGG domain protein - - - 0.00000000000000000000000004138 111.0
TH2_k127_6646014_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 545.0
TH2_k127_6646014_1 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 464.0
TH2_k127_6646014_10 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000006437 226.0
TH2_k127_6646014_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000001802 211.0
TH2_k127_6646014_12 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000009338 171.0
TH2_k127_6646014_13 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000638 118.0
TH2_k127_6646014_14 - - - - 0.000000000000000006565 88.0
TH2_k127_6646014_15 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.000000000000000007071 87.0
TH2_k127_6646014_16 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000004476 92.0
TH2_k127_6646014_2 Biotin-protein ligase, N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 357.0
TH2_k127_6646014_3 PFAM Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 344.0
TH2_k127_6646014_4 Hydrogenase expression formation protein (HypE) K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002983 277.0
TH2_k127_6646014_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004187 244.0
TH2_k127_6646014_6 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000001003 245.0
TH2_k127_6646014_7 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000003322 243.0
TH2_k127_6646014_8 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000001868 236.0
TH2_k127_6646014_9 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000006771 234.0
TH2_k127_670211_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 2.962e-204 650.0
TH2_k127_670211_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 536.0
TH2_k127_670211_2 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 411.0
TH2_k127_670211_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 327.0
TH2_k127_670211_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000003624 127.0
TH2_k127_6702274_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001068 276.0
TH2_k127_6702274_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000001033 229.0
TH2_k127_6702274_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000003264 208.0
TH2_k127_6702274_3 lysyltransferase activity K07027,K20468 - - 0.000000000000000000000000000000000005579 150.0
TH2_k127_6702274_4 Transposase IS200 like - - - 0.00000000000000000000001056 106.0
TH2_k127_6702274_5 Acetyltransferase (GNAT) domain - - - 0.000000000005499 77.0
TH2_k127_6702274_6 Nodulation protein S (NodS) - - - 0.000000003856 66.0
TH2_k127_6726731_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1601.0
TH2_k127_6726731_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.615e-299 931.0
TH2_k127_6726731_10 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 355.0
TH2_k127_6726731_11 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 291.0
TH2_k127_6726731_12 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001326 256.0
TH2_k127_6726731_13 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002809 252.0
TH2_k127_6726731_14 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000001915 226.0
TH2_k127_6726731_15 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000005579 198.0
TH2_k127_6726731_16 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000007033 188.0
TH2_k127_6726731_17 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000009129 154.0
TH2_k127_6726731_18 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000033 153.0
TH2_k127_6726731_19 COGs COG3093 Plasmid maintenance system antidote protein K21498 - - 0.000000000000000000000000000000000002256 140.0
TH2_k127_6726731_2 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 4.867e-290 897.0
TH2_k127_6726731_20 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000121 146.0
TH2_k127_6726731_21 GYD domain - - - 0.00000000000000000000000000000000003169 136.0
TH2_k127_6726731_22 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000006072 121.0
TH2_k127_6726731_23 nucleic acid-binding protein, contains PIN domain - - - 0.00000000000000000000000000004785 121.0
TH2_k127_6726731_24 Histidine kinase - - - 0.000000000000000000000001962 115.0
TH2_k127_6726731_25 AbrB family - - - 0.0000000000002922 72.0
TH2_k127_6726731_26 23S rRNA-intervening sequence protein K13010 - 2.6.1.102 0.000000000000782 74.0
TH2_k127_6726731_27 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000007407 57.0
TH2_k127_6726731_28 parallel beta-helix repeat (two copies) - - - 0.0000001123 63.0
TH2_k127_6726731_29 TonB C terminal K03832 - - 0.00005972 45.0
TH2_k127_6726731_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.946e-271 842.0
TH2_k127_6726731_4 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 604.0
TH2_k127_6726731_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 553.0
TH2_k127_6726731_6 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 507.0
TH2_k127_6726731_7 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit K02433,K21801 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 505.0
TH2_k127_6726731_8 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 485.0
TH2_k127_6726731_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 434.0
TH2_k127_6738572_0 Strictosidine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 441.0
TH2_k127_6738572_1 aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 316.0
TH2_k127_6738572_2 phosphoribosylamine-glycine ligase activity K01945,K01955 - 6.3.4.13,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000002957 240.0
TH2_k127_6738572_3 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000003465 228.0
TH2_k127_6738572_4 EthD domain - - - 0.000000000000000000000000000000000000001368 149.0
TH2_k127_6738572_5 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000397 75.0
TH2_k127_6738572_6 Membrane - - - 0.000001181 53.0
TH2_k127_6784719_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.557e-257 807.0
TH2_k127_6784719_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.826e-197 627.0
TH2_k127_6784719_10 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 329.0
TH2_k127_6784719_11 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 328.0
TH2_k127_6784719_12 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 305.0
TH2_k127_6784719_13 PFAM Acyl-CoA dehydrogenase K00248,K22430 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108,1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 300.0
TH2_k127_6784719_14 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008121 289.0
TH2_k127_6784719_15 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004515 280.0
TH2_k127_6784719_16 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000005735 226.0
TH2_k127_6784719_17 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000008231 221.0
TH2_k127_6784719_18 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000001347 186.0
TH2_k127_6784719_19 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124 - - 0.000000000000000000000000000000000007367 141.0
TH2_k127_6784719_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 544.0
TH2_k127_6784719_20 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.000000000000000000000000000000005567 130.0
TH2_k127_6784719_21 Enoyl-CoA hydratase/isomerase K13767 - 4.2.1.17 0.0000000001587 63.0
TH2_k127_6784719_22 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000005511 60.0
TH2_k127_6784719_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 478.0
TH2_k127_6784719_4 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 479.0
TH2_k127_6784719_5 Thi4 family K00313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 436.0
TH2_k127_6784719_6 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 409.0
TH2_k127_6784719_7 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 404.0
TH2_k127_6784719_8 lactate metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 367.0
TH2_k127_6784719_9 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 356.0
TH2_k127_6793075_0 Amidohydrolase family - - - 2.974e-239 750.0
TH2_k127_6793075_1 Imidazolonepropionase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 360.0
TH2_k127_6793075_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 291.0
TH2_k127_6793075_3 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000000164 113.0
TH2_k127_6793075_4 Regulatory protein, FmdB family - - - 0.000000000000001567 79.0
TH2_k127_6796056_0 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 324.0
TH2_k127_6796056_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008423 256.0
TH2_k127_6799427_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.696e-298 930.0
TH2_k127_6799427_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 573.0
TH2_k127_6799427_10 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 293.0
TH2_k127_6799427_11 Belongs to the TtcA family K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005791 258.0
TH2_k127_6799427_12 PFAM HhH-GPD superfamily base excision DNA repair protein K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003997 253.0
TH2_k127_6799427_13 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000911 126.0
TH2_k127_6799427_14 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000004431 99.0
TH2_k127_6799427_15 Biopolymer transport protein ExbD K03559 - - 0.000000000003837 69.0
TH2_k127_6799427_16 PhoQ Sensor - - - 0.00000008083 63.0
TH2_k127_6799427_2 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 412.0
TH2_k127_6799427_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 398.0
TH2_k127_6799427_4 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 388.0
TH2_k127_6799427_5 ABC-2 type transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009548 377.0
TH2_k127_6799427_6 PFAM ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 370.0
TH2_k127_6799427_7 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 348.0
TH2_k127_6799427_8 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 310.0
TH2_k127_6799427_9 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 302.0
TH2_k127_6838493_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 521.0
TH2_k127_6838493_1 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 480.0
TH2_k127_6838493_10 BioY family K03523 - - 0.000000000000000000000000000000000000000000000000000000003342 207.0
TH2_k127_6838493_11 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000006109 196.0
TH2_k127_6838493_12 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000008101 191.0
TH2_k127_6838493_13 - - - - 0.0000000000000000000000000000000000000001391 155.0
TH2_k127_6838493_14 Amidohydrolase - - - 0.00000000000000000000000000000000002393 146.0
TH2_k127_6838493_15 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000001716 109.0
TH2_k127_6838493_16 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000002838 104.0
TH2_k127_6838493_17 phosphorelay signal transduction system K03413,K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.00000000005321 68.0
TH2_k127_6838493_2 Peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 441.0
TH2_k127_6838493_3 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 391.0
TH2_k127_6838493_4 Responsible for energy coupling to the transport system K16784 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 329.0
TH2_k127_6838493_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001432 275.0
TH2_k127_6838493_6 FtsZ-dependent cytokinesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002965 243.0
TH2_k127_6838493_7 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006846 241.0
TH2_k127_6838493_8 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000005475 238.0
TH2_k127_6838493_9 Cobalt transport protein K16783,K16785 - - 0.000000000000000000000000000000000000000000000000000000000000001025 228.0
TH2_k127_6840113_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 590.0
TH2_k127_6840113_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 568.0
TH2_k127_6840113_10 PFAM FAD linked oxidase domain protein K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 324.0
TH2_k127_6840113_11 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 308.0
TH2_k127_6840113_12 Tripartite ATP-independent periplasmic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 300.0
TH2_k127_6840113_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 303.0
TH2_k127_6840113_14 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 295.0
TH2_k127_6840113_15 PFAM Pterin binding enzyme K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008411 281.0
TH2_k127_6840113_16 P-loop containing region of AAA domain K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002619 266.0
TH2_k127_6840113_17 cobalamin binding K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000001136 240.0
TH2_k127_6840113_18 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000007659 233.0
TH2_k127_6840113_19 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000164 190.0
TH2_k127_6840113_2 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 524.0
TH2_k127_6840113_20 - - - - 0.000000000000000000000000000000000001802 141.0
TH2_k127_6840113_21 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000618 144.0
TH2_k127_6840113_22 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000001591 102.0
TH2_k127_6840113_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 520.0
TH2_k127_6840113_4 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 444.0
TH2_k127_6840113_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 420.0
TH2_k127_6840113_6 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 365.0
TH2_k127_6840113_7 Methionyl-tRNA formyltransferase K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 339.0
TH2_k127_6840113_8 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 331.0
TH2_k127_6840113_9 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 325.0
TH2_k127_6851029_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 498.0
TH2_k127_6851029_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 317.0
TH2_k127_6851029_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000001401 107.0
TH2_k127_6851029_11 PHP domain K07053 - 3.1.3.97 0.000003977 57.0
TH2_k127_6851029_2 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003249 285.0
TH2_k127_6851029_3 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001224 254.0
TH2_k127_6851029_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000008365 224.0
TH2_k127_6851029_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000132 188.0
TH2_k127_6851029_6 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000000000000000000000003246 187.0
TH2_k127_6851029_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000003512 128.0
TH2_k127_6852471_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 481.0
TH2_k127_6852471_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 384.0
TH2_k127_6852471_2 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 332.0
TH2_k127_6852471_3 NosL - - - 0.0000000000000000000000000000000000000000000000000009633 188.0
TH2_k127_6852471_4 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000001244 142.0
TH2_k127_6852471_5 - - - - 0.0000000000000000000000002272 108.0
TH2_k127_6852471_6 galactose-1-phosphate K00965 - 2.7.7.12 0.00000000000000000000000728 104.0
TH2_k127_6852471_7 NosL - - - 0.00000000000000001024 83.0
TH2_k127_6852471_8 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02243,K02652 - - 0.000000000000385 76.0
TH2_k127_6868990_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1630.0
TH2_k127_6868990_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 7.918e-258 799.0
TH2_k127_6868990_2 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000554 570.0
TH2_k127_6868990_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 424.0
TH2_k127_6868990_4 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 412.0
TH2_k127_6868990_5 4fe-4S ferredoxin, iron-sulfur binding domain protein K19516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 299.0
TH2_k127_6868990_6 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000001916 113.0
TH2_k127_693510_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.068e-217 691.0
TH2_k127_693510_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 295.0
TH2_k127_6990293_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600,K00605,K18847 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.1,2.1.2.10,2.2.1.8 0.0 1021.0
TH2_k127_6990293_1 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 532.0
TH2_k127_6990293_2 YhhN family - - - 0.00000000000000000000000002289 117.0
TH2_k127_6990293_3 GYD domain - - - 0.00007344 45.0
TH2_k127_7028819_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 612.0
TH2_k127_7061267_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 398.0
TH2_k127_7061267_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000003807 242.0
TH2_k127_70627_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 593.0
TH2_k127_70627_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 392.0
TH2_k127_70627_10 - - - - 0.00003119 51.0
TH2_k127_70627_11 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.0007259 45.0
TH2_k127_70627_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 372.0
TH2_k127_70627_3 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006781 254.0
TH2_k127_70627_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000006987 239.0
TH2_k127_70627_5 PFAM SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000003256 189.0
TH2_k127_70627_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000002295 153.0
TH2_k127_70627_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000002457 156.0
TH2_k127_70627_8 Major Facilitator Superfamily - - - 0.000000000000937 73.0
TH2_k127_70627_9 PFAM L-lactate permease K02550,K03303 - - 0.000000713 53.0
TH2_k127_7209912_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000002722 238.0
TH2_k127_7209912_1 Lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000522 165.0
TH2_k127_7209912_2 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000002009 160.0
TH2_k127_7209912_3 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000001736 150.0
TH2_k127_72251_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 373.0
TH2_k127_72251_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000006197 171.0
TH2_k127_7230418_0 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 546.0
TH2_k127_7230418_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 420.0
TH2_k127_7230418_2 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 404.0
TH2_k127_7230418_3 PFAM Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006579 258.0
TH2_k127_7230418_4 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000002629 242.0
TH2_k127_7230418_5 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000001643 135.0
TH2_k127_7230418_6 Glycine cleavage H-protein - - - 0.0000000000000000000000003116 108.0
TH2_k127_7230418_7 Transposase IS200 like K07491 - - 0.0000000000000003139 85.0
TH2_k127_7409750_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 1.682e-283 897.0
TH2_k127_7409750_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.94e-258 813.0
TH2_k127_7409750_10 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000001293 216.0
TH2_k127_7409750_11 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000006175 209.0
TH2_k127_7409750_12 Hit family K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000005515 194.0
TH2_k127_7409750_13 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000009464 187.0
TH2_k127_7409750_14 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000008232 175.0
TH2_k127_7409750_15 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000167 147.0
TH2_k127_7409750_16 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000001096 137.0
TH2_k127_7409750_17 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000001192 127.0
TH2_k127_7409750_18 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000000158 108.0
TH2_k127_7409750_19 Nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.00000000003458 67.0
TH2_k127_7409750_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.32e-253 807.0
TH2_k127_7409750_20 Lipopolysaccharide assembly protein A domain K08992 - - 0.000002576 55.0
TH2_k127_7409750_3 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 473.0
TH2_k127_7409750_4 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 457.0
TH2_k127_7409750_5 tyrosine recombinase K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 327.0
TH2_k127_7409750_6 signal peptide peptidase SppA K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001802 280.0
TH2_k127_7409750_7 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000005328 260.0
TH2_k127_7409750_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000001351 248.0
TH2_k127_7409750_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000002307 234.0
TH2_k127_7441210_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 375.0
TH2_k127_7441210_1 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 364.0
TH2_k127_7441210_2 Transposase K07494 - - 0.00000000000000000000000005115 109.0
TH2_k127_7441210_3 - - - - 0.00003364 46.0
TH2_k127_7450798_0 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005764 254.0
TH2_k127_7450798_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000006158 86.0
TH2_k127_7450973_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 5e-324 1005.0
TH2_k127_7450973_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.681e-244 766.0
TH2_k127_7450973_10 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001559 248.0
TH2_k127_7450973_11 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000003651 201.0
TH2_k127_7450973_12 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000002796 170.0
TH2_k127_7450973_13 protein conserved in bacteria - - - 0.000000000000000000000000000008978 122.0
TH2_k127_7450973_14 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000000005935 98.0
TH2_k127_7450973_2 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 1.876e-196 620.0
TH2_k127_7450973_3 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 479.0
TH2_k127_7450973_4 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 441.0
TH2_k127_7450973_5 carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 421.0
TH2_k127_7450973_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 381.0
TH2_k127_7450973_7 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 376.0
TH2_k127_7450973_8 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 370.0
TH2_k127_7450973_9 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 344.0
TH2_k127_7477036_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 5.222e-242 767.0
TH2_k127_7477036_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 541.0
TH2_k127_7477036_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000006887 246.0
TH2_k127_7477036_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000007247 228.0
TH2_k127_7477036_12 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000002883 192.0
TH2_k127_7477036_13 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000001333 135.0
TH2_k127_7477036_14 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000003152 99.0
TH2_k127_7477036_15 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00004522 49.0
TH2_k127_7477036_2 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 536.0
TH2_k127_7477036_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 461.0
TH2_k127_7477036_4 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 413.0
TH2_k127_7477036_5 PFAM Extracellular ligand-binding receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 396.0
TH2_k127_7477036_6 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 364.0
TH2_k127_7477036_7 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 348.0
TH2_k127_7477036_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 338.0
TH2_k127_7477036_9 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 322.0
TH2_k127_7487238_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.205e-208 655.0
TH2_k127_7487238_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 460.0
TH2_k127_7487238_10 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000006604 146.0
TH2_k127_7487238_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000000005158 137.0
TH2_k127_7487238_12 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000005062 71.0
TH2_k127_7487238_13 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000108 71.0
TH2_k127_7487238_14 Salmonella virulence plasmid 28.1kDa A protein K07127 GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.2.17 0.000001696 52.0
TH2_k127_7487238_2 Salmonella virulence plasmid 28.1kDa A protein K07127 GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 465.0
TH2_k127_7487238_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 310.0
TH2_k127_7487238_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 287.0
TH2_k127_7487238_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000002812 224.0
TH2_k127_7487238_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000003218 210.0
TH2_k127_7487238_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000002399 178.0
TH2_k127_7487238_8 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000002288 168.0
TH2_k127_7487238_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000003613 147.0
TH2_k127_7520060_0 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 483.0
TH2_k127_7520060_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000003712 237.0
TH2_k127_7520060_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000001233 175.0
TH2_k127_7624636_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 495.0
TH2_k127_7624636_1 Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 490.0
TH2_k127_7624636_2 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002584 277.0
TH2_k127_7624636_4 Helix-turn-helix domain - - - 0.000005772 51.0
TH2_k127_7733825_0 PFAM Aldehyde dehydrogenase - - - 3.885e-283 873.0
TH2_k127_7733825_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 366.0
TH2_k127_7733825_2 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 366.0
TH2_k127_7733825_3 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006221 258.0
TH2_k127_7733825_4 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003665 256.0
TH2_k127_7733825_5 pyruvate phosphate dikinase, PEP K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000119 251.0
TH2_k127_7733825_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003765 248.0
TH2_k127_7733825_7 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000007803 240.0
TH2_k127_7813037_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 619.0
TH2_k127_7813037_1 Polysaccharide export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000001988 217.0
TH2_k127_7813037_2 Tetratricopeptide repeat - - - 0.0000000000000000002515 101.0
TH2_k127_7813037_3 SMART heat shock protein DnaJ domain protein K05516 - - 0.00000000001412 76.0
TH2_k127_7813125_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 451.0
TH2_k127_7813125_1 TIGRFAM reductive dehalogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 338.0
TH2_k127_7813125_2 Tannase and feruloyl esterase K21105 - 3.1.1.102 0.00000000000000000000000000000000000000000000000000000000000000005084 243.0
TH2_k127_7813125_3 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000008818 129.0
TH2_k127_7813125_4 Zinc-dependent metalloprotease - - - 0.00000000000000000000000000006128 129.0
TH2_k127_7813125_5 Belongs to the 'phage' integrase family - - - 0.0000000000002213 73.0
TH2_k127_7813125_6 Belongs to the 'phage' integrase family - - - 0.0000000001288 66.0
TH2_k127_7817610_0 Putative RNA methylase family UPF0020 - - - 0.00000000000000000000000000000000000000000000000000000006239 213.0
TH2_k127_7817610_1 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000005972 150.0
TH2_k127_7817610_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000004157 134.0
TH2_k127_7817610_3 - - - - 0.000000008289 62.0
TH2_k127_7827119_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.873e-309 976.0
TH2_k127_7827119_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 6.758e-228 722.0
TH2_k127_7827119_2 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 611.0
TH2_k127_7827119_3 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 305.0
TH2_k127_7827119_4 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000194 245.0
TH2_k127_7827119_5 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000005178 190.0
TH2_k127_7827119_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00125 - 1.17.1.9 0.000003652 51.0
TH2_k127_7896883_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.221e-248 783.0
TH2_k127_7896883_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 304.0
TH2_k127_7896883_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000002635 77.0
TH2_k127_7923081_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.0 1412.0
TH2_k127_7923081_1 FecR protein - - - 0.0 1202.0
TH2_k127_7923081_10 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 309.0
TH2_k127_7923081_11 Bacterial transferase hexapeptide (six repeats) K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000736 272.0
TH2_k127_7923081_12 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003615 274.0
TH2_k127_7923081_13 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007481 284.0
TH2_k127_7923081_14 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009729 279.0
TH2_k127_7923081_15 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008267 263.0
TH2_k127_7923081_16 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000009527 269.0
TH2_k127_7923081_17 pyruvate phosphate dikinase, PEP K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000008209 263.0
TH2_k127_7923081_18 Histidine kinase HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000001491 253.0
TH2_k127_7923081_19 Isochorismatase family K09020 - 3.5.1.110 0.000000000000000000000000000000000000000000000000000000000000000003267 233.0
TH2_k127_7923081_2 CHASE2 K01768 - 4.6.1.1 1.214e-243 774.0
TH2_k127_7923081_20 PFAM AzlC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000006331 223.0
TH2_k127_7923081_21 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000003761 201.0
TH2_k127_7923081_22 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000001202 196.0
TH2_k127_7923081_23 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000002445 195.0
TH2_k127_7923081_24 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000001729 153.0
TH2_k127_7923081_25 Putative Fe-S cluster - - - 0.000000000000000000000000000000000000008664 151.0
TH2_k127_7923081_26 membrane K08978 - - 0.00000000000000000000000000000000001303 140.0
TH2_k127_7923081_27 DGC domain - - - 0.00000000000000000000000000000002136 130.0
TH2_k127_7923081_28 Thioesterase superfamily - - - 0.000000000000000000000000000001305 125.0
TH2_k127_7923081_29 - - - - 0.00000000000000000000000001051 111.0
TH2_k127_7923081_3 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 623.0
TH2_k127_7923081_30 membrane-associated protein K03975 - - 0.0000000000000000000000001553 114.0
TH2_k127_7923081_31 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000003836 108.0
TH2_k127_7923081_32 regulatory protein, arsR K03892 - - 0.0000000000000000000000006407 107.0
TH2_k127_7923081_33 Thioredoxin domain - - - 0.000000000000000000000002463 108.0
TH2_k127_7923081_34 Thioredoxin K03671 - - 0.0000000000000000000005179 100.0
TH2_k127_7923081_35 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.0000000000000000001821 89.0
TH2_k127_7923081_36 branched-chain amino acid - - - 0.000000000000000001618 88.0
TH2_k127_7923081_37 Ferredoxin K05337 - - 0.000000000000001176 78.0
TH2_k127_7923081_38 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.0000000000000128 84.0
TH2_k127_7923081_39 PFAM Bile acid sodium symporter K03325 - - 0.0000000000002624 70.0
TH2_k127_7923081_4 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 501.0
TH2_k127_7923081_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 500.0
TH2_k127_7923081_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 471.0
TH2_k127_7923081_7 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 374.0
TH2_k127_7923081_8 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 368.0
TH2_k127_7923081_9 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 324.0
TH2_k127_7933928_0 Valyl tRNA synthetase tRNA binding arm K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.339e-298 926.0
TH2_k127_7933928_1 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 440.0
TH2_k127_7933928_2 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000001568 207.0
TH2_k127_7933928_3 response regulator receiver - - - 0.000002589 60.0
TH2_k127_7948416_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 541.0
TH2_k127_7948416_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 527.0
TH2_k127_7948416_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 356.0
TH2_k127_7948416_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 302.0
TH2_k127_7948416_4 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000002291 133.0
TH2_k127_7948416_5 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000000000000008781 115.0
TH2_k127_7948416_6 Transglutaminase-like superfamily - - - 0.0000000000000000002056 93.0
TH2_k127_8000267_0 Beta-eliminating lyase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 537.0
TH2_k127_8000267_1 addiction module antidote protein HigA - - - 0.00000000000000000000000004279 112.0
TH2_k127_8000267_2 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000001768 103.0
TH2_k127_8000267_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000006494 106.0
TH2_k127_8000267_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000002113 89.0
TH2_k127_8000267_5 - - - - 0.0000000000000004873 79.0
TH2_k127_8000267_6 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000003753 70.0
TH2_k127_8000267_7 Domain of unknown function (DUF362) - - - 0.0000000004444 65.0
TH2_k127_8000267_8 - - - - 0.0000003157 54.0
TH2_k127_8033366_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 3.79e-292 903.0
TH2_k127_8033366_1 coenzyme F390 K01912 - 6.2.1.30 2.4e-223 701.0
TH2_k127_8033366_10 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 400.0
TH2_k127_8033366_11 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 401.0
TH2_k127_8033366_12 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 345.0
TH2_k127_8033366_13 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 348.0
TH2_k127_8033366_14 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 328.0
TH2_k127_8033366_15 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 305.0
TH2_k127_8033366_16 Lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 308.0
TH2_k127_8033366_17 Formyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 293.0
TH2_k127_8033366_18 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005129 260.0
TH2_k127_8033366_2 TIGRFAM cysteine desulfurase family protein K11717 - 2.8.1.7,4.4.1.16 8.208e-198 622.0
TH2_k127_8033366_20 Polysaccharide deacetylase K11931 - - 0.000000000000000000000000000000000000000000000000001623 192.0
TH2_k127_8033366_21 CobQ/CobB/MinD/ParA nucleotide binding domain K08252 - 2.7.10.1 0.000000000000000000000000000000000000000000000003109 185.0
TH2_k127_8033366_22 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000009414 164.0
TH2_k127_8033366_23 histidine kinase - - - 0.000000000000000000000000000000000000000002336 169.0
TH2_k127_8033366_24 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000201 117.0
TH2_k127_8033366_25 Transcription termination factor nusG - - - 0.0000000000000000000000008817 109.0
TH2_k127_8033366_26 Putative beta-barrel porin 2 - - - 0.00000000000000000000001529 114.0
TH2_k127_8033366_27 Diguanylate cyclase - - - 0.000000000001699 78.0
TH2_k127_8033366_28 GGDEF domain K19707 - - 0.00000002877 61.0
TH2_k127_8033366_29 diguanylate cyclase - - - 0.000002298 56.0
TH2_k127_8033366_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 542.0
TH2_k127_8033366_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 541.0
TH2_k127_8033366_5 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 471.0
TH2_k127_8033366_6 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 470.0
TH2_k127_8033366_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 462.0
TH2_k127_8033366_8 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 442.0
TH2_k127_8033366_9 Domain of unknown function (DUF3473) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 396.0
TH2_k127_8087944_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 396.0
TH2_k127_8087944_1 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000001372 214.0
TH2_k127_8087944_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000006907 135.0
TH2_k127_8087944_3 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000006447 96.0
TH2_k127_8095450_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1412.0
TH2_k127_8095450_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K21577 - 1.21.4.2,1.21.4.3,1.21.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 567.0
TH2_k127_8095450_10 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 316.0
TH2_k127_8095450_11 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 305.0
TH2_k127_8095450_12 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003831 291.0
TH2_k127_8095450_13 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005274 261.0
TH2_k127_8095450_14 Psort location Cytoplasmic, score K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009308 246.0
TH2_k127_8095450_15 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001392 245.0
TH2_k127_8095450_16 COG NOG06476 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000000001663 249.0
TH2_k127_8095450_17 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000885 222.0
TH2_k127_8095450_18 Cytochrome b5-like Heme/Steroid binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000004103 218.0
TH2_k127_8095450_19 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000005028 208.0
TH2_k127_8095450_2 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 513.0
TH2_k127_8095450_20 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000001493 192.0
TH2_k127_8095450_21 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000002027 205.0
TH2_k127_8095450_22 TIGRFAM beta-ketoadipate pathway transcriptional regulators, PcaR PcaU PobR family K02624 - - 0.0000000000000000000000000000000000000000000000001863 187.0
TH2_k127_8095450_23 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000001985 162.0
TH2_k127_8095450_24 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000002604 139.0
TH2_k127_8095450_25 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000005802 128.0
TH2_k127_8095450_26 In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.000000000000000000000000008377 113.0
TH2_k127_8095450_27 Rubrerythrin - - - 0.00000000000000000000000001879 113.0
TH2_k127_8095450_28 PFAM Galactose-1-phosphate uridyl transferase K00965 - 2.7.7.12 0.0000000000000000000001336 100.0
TH2_k127_8095450_29 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.000000000000000000001639 100.0
TH2_k127_8095450_3 NAD(P)H dehydrogenase (quinone) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 490.0
TH2_k127_8095450_30 Rubredoxin - - - 0.000000000000000000001664 94.0
TH2_k127_8095450_31 iron ion binding - - - 0.0000000000000000004385 89.0
TH2_k127_8095450_32 KR domain K18009 - 1.1.1.304,1.1.1.76 0.000000000000000002031 94.0
TH2_k127_8095450_33 permease K07243 - - 0.0000000000000001359 84.0
TH2_k127_8095450_34 TIGRFAM selenoprotein B, glycine betaine sarcosine D-proline reductase family K21579 - 1.21.4.4 0.00000000000001466 76.0
TH2_k127_8095450_35 indolepyruvate ferredoxin oxidoreductase activity K00176,K03616,K08941 - 1.2.7.3 0.000000000000253 72.0
TH2_k127_8095450_36 - - - - 0.000000000002126 70.0
TH2_k127_8095450_37 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000716 72.0
TH2_k127_8095450_38 - - - - 0.0000000006271 65.0
TH2_k127_8095450_39 the current gene model (or a revised gene model) may contain a premature stop K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0000000008801 60.0
TH2_k127_8095450_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 491.0
TH2_k127_8095450_40 Sigma-54 interaction domain K10126 - - 0.000000001351 63.0
TH2_k127_8095450_42 Rubrerythrin - - - 0.0000000773 63.0
TH2_k127_8095450_43 - - - - 0.00006113 49.0
TH2_k127_8095450_5 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 454.0
TH2_k127_8095450_6 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 401.0
TH2_k127_8095450_7 TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 407.0
TH2_k127_8095450_8 Glycine reductase complex component B subunit gamma K10672 - 1.21.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 364.0
TH2_k127_8095450_9 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 364.0
TH2_k127_8145839_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 330.0
TH2_k127_8145839_1 PFAM Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005286 282.0
TH2_k127_8145839_2 PFAM response regulator receiver - - - 0.00000000000000000000000000001154 123.0
TH2_k127_8145839_3 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000539 43.0
TH2_k127_8159433_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K07469 - 1.2.99.7 0.0 1241.0
TH2_k127_8159433_1 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 3.293e-274 852.0
TH2_k127_8159433_2 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 581.0
TH2_k127_8159433_3 COG1233 Phytoene dehydrogenase and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 570.0
TH2_k127_8159433_4 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 353.0
TH2_k127_8159433_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 337.0
TH2_k127_8159433_6 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 327.0
TH2_k127_8159433_7 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000006302 213.0
TH2_k127_8159433_8 - - - - 0.00000000000000000000000000000000000000000000001143 177.0
TH2_k127_8159433_9 heme oxygenase (decyclizing) activity K21481 - 1.14.99.57 0.000000000000000000000000000000000001049 141.0
TH2_k127_8180459_0 PHP-associated K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000003196 214.0
TH2_k127_8180459_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000629 197.0
TH2_k127_8180459_2 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000003426 175.0
TH2_k127_8180459_3 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000000000001178 152.0
TH2_k127_8180459_4 Ferredoxin K17992 - 1.12.1.3 0.00000000000000000000000000000006063 127.0
TH2_k127_8180459_5 DRTGG domain - - - 0.0000000000000000000000000000001286 128.0
TH2_k127_822991_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.924e-209 661.0
TH2_k127_822991_1 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 370.0
TH2_k127_822991_10 TIGRFAM ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.0000000005034 71.0
TH2_k127_822991_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 330.0
TH2_k127_822991_3 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001836 286.0
TH2_k127_822991_4 ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007472 259.0
TH2_k127_822991_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000001168 257.0
TH2_k127_822991_6 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000008604 224.0
TH2_k127_822991_7 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component - - - 0.0000000000000000000000000000000000000000000000001647 186.0
TH2_k127_822991_8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000002155 74.0
TH2_k127_822991_9 4 iron, 4 sulfur cluster binding - - - 0.000000000001548 70.0
TH2_k127_8232005_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 435.0
TH2_k127_8232005_1 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 346.0
TH2_k127_8232005_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 302.0
TH2_k127_8232005_3 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004065 242.0
TH2_k127_8232005_4 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000002759 221.0
TH2_k127_8232005_5 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000000000001455 207.0
TH2_k127_8232005_6 cheY-homologous receiver domain - - - 0.0005081 44.0
TH2_k127_8244239_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 450.0
TH2_k127_8244239_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 403.0
TH2_k127_8244239_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 334.0
TH2_k127_8244239_3 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000001171 210.0
TH2_k127_8244239_4 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000004188 179.0
TH2_k127_8244239_5 virion core protein, lumpy skin disease virus - - - 0.000000000000000000000000000000000000000001279 164.0
TH2_k127_8244239_6 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000001396 124.0
TH2_k127_8244239_7 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000001299 112.0
TH2_k127_8244239_8 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000002592 76.0
TH2_k127_8244239_9 PAS fold - - - 0.0000000000004666 72.0
TH2_k127_824679_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.914e-233 735.0
TH2_k127_824679_1 Pyridoxal-phosphate dependent enzyme - - - 7.501e-198 626.0
TH2_k127_824679_10 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 375.0
TH2_k127_824679_11 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 361.0
TH2_k127_824679_12 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 332.0
TH2_k127_824679_13 ABC transporter permease K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 310.0
TH2_k127_824679_14 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 295.0
TH2_k127_824679_15 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000279 271.0
TH2_k127_824679_16 PFAM Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001339 261.0
TH2_k127_824679_17 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003909 262.0
TH2_k127_824679_18 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004403 260.0
TH2_k127_824679_19 Bacterial transcriptional repressor C-terminal K16137 - - 0.0000000000000000000000000000000000000000000000000000000000000000003588 235.0
TH2_k127_824679_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 578.0
TH2_k127_824679_20 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000001109 228.0
TH2_k127_824679_21 PFAM Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000002975 225.0
TH2_k127_824679_22 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000001382 195.0
TH2_k127_824679_23 Flavodoxin K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000002045 166.0
TH2_k127_824679_24 Cupin domain - - - 0.000000000000000000000000000000006681 135.0
TH2_k127_824679_25 - K21399 GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 2.3.1.263 0.000000000000000000000000001979 114.0
TH2_k127_824679_26 rubredoxin - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0017144,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114,GO:0072592 - 0.00000000000000000000000006812 107.0
TH2_k127_824679_27 Major facilitator superfamily - - - 0.00000000000002227 85.0
TH2_k127_824679_28 ThiS family - - - 0.0000000000002182 73.0
TH2_k127_824679_29 SnoaL-like polyketide cyclase - - - 0.00000000004978 68.0
TH2_k127_824679_3 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 541.0
TH2_k127_824679_30 PFAM ThiamineS - - - 0.00000009437 57.0
TH2_k127_824679_4 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 486.0
TH2_k127_824679_5 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 456.0
TH2_k127_824679_6 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 455.0
TH2_k127_824679_7 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 406.0
TH2_k127_824679_8 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 397.0
TH2_k127_824679_9 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 391.0
TH2_k127_8261159_0 BadF BadG BcrA BcrD - - - 0.0 1660.0
TH2_k127_8261159_1 Sulfatase K01130 - 3.1.6.1 0.0 1412.0
TH2_k127_8261159_2 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 524.0
TH2_k127_8261159_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 345.0
TH2_k127_8261159_4 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 302.0
TH2_k127_8261159_5 binding domain protein - - - 0.00000000000000000000000000000000000000002543 162.0
TH2_k127_8261159_6 Ion transport 2 domain protein - - - 0.00000000000000000000000000000000002006 144.0
TH2_k127_8261159_7 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000000004044 115.0
TH2_k127_8261159_8 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000002255 79.0
TH2_k127_8268752_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 4.263e-304 940.0
TH2_k127_8268752_1 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 524.0
TH2_k127_8268752_2 ABC transporter K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 421.0
TH2_k127_8268752_3 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 407.0
TH2_k127_8268752_4 TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 343.0
TH2_k127_8268752_5 phosphate transporter K03306,K16322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 331.0
TH2_k127_8268752_6 PFAM binding-protein-dependent transport systems inner membrane component K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 316.0
TH2_k127_8268752_7 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 298.0
TH2_k127_8268752_8 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008137 280.0
TH2_k127_8268752_9 transmembrane transport K05814,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005044 268.0
TH2_k127_8280496_0 Alpha amylase, catalytic domain - - - 0.0 1455.0
TH2_k127_8280496_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 399.0
TH2_k127_8280496_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 362.0
TH2_k127_8280496_3 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 328.0
TH2_k127_8280496_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000005601 206.0
TH2_k127_8280496_5 PFAM S23 ribosomal protein - - - 0.0000000000000000000000000000000000031 140.0
TH2_k127_8280496_6 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.00000000000000000000000004109 112.0
TH2_k127_8280496_7 Biotin carboxylase C-terminal domain - - - 0.000000000000000000000009769 102.0
TH2_k127_8280496_8 - - - - 0.0000000001311 66.0
TH2_k127_8308647_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.545e-222 696.0
TH2_k127_8308647_1 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 541.0
TH2_k127_8308647_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000001301 238.0
TH2_k127_8308647_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000004046 187.0
TH2_k127_8308647_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00005684 46.0
TH2_k127_8308647_6 Uncharacterised protein family (UPF0261) - - - 0.0002418 49.0
TH2_k127_8345058_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 7.327e-259 812.0
TH2_k127_8345058_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.366e-219 695.0
TH2_k127_8345058_10 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 327.0
TH2_k127_8345058_11 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
TH2_k127_8345058_12 COG0618 Exopolyphosphatase-related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 317.0
TH2_k127_8345058_13 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 295.0
TH2_k127_8345058_14 Cytochrome b(N-terminal)/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 290.0
TH2_k127_8345058_15 Beta-lactamase enzyme family K07258,K07262 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 299.0
TH2_k127_8345058_16 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000006767 243.0
TH2_k127_8345058_17 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000004395 229.0
TH2_k127_8345058_18 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000000001213 220.0
TH2_k127_8345058_19 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000000000000001215 206.0
TH2_k127_8345058_2 PFAM beta-lactamase domain protein - - - 4.155e-214 680.0
TH2_k127_8345058_20 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000001399 210.0
TH2_k127_8345058_21 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000002963 202.0
TH2_k127_8345058_22 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000006915 203.0
TH2_k127_8345058_23 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.00000000000000000000000000000000000000000000009239 175.0
TH2_k127_8345058_24 Cytochrome b(C-terminal)/b6/petD - - - 0.0000000000000000000000000000000000000002539 155.0
TH2_k127_8345058_25 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000009081 152.0
TH2_k127_8345058_26 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000001445 128.0
TH2_k127_8345058_27 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000000000597 110.0
TH2_k127_8345058_28 hydrolase - - - 0.0000000000000000000014 106.0
TH2_k127_8345058_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 2.37e-200 640.0
TH2_k127_8345058_30 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000002854 94.0
TH2_k127_8345058_31 6-phospho-beta-galactosidase activity - - - 0.00000000000000000008174 102.0
TH2_k127_8345058_33 Chromatin associated protein KTI12 - - - 0.0001021 52.0
TH2_k127_8345058_4 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 3.401e-194 625.0
TH2_k127_8345058_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 522.0
TH2_k127_8345058_6 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 456.0
TH2_k127_8345058_7 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 443.0
TH2_k127_8345058_8 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 392.0
TH2_k127_8345058_9 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 336.0
TH2_k127_8378288_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 473.0
TH2_k127_8378288_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000003757 214.0
TH2_k127_8378288_2 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000005851 200.0
TH2_k127_8378288_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000003834 192.0
TH2_k127_8382448_0 Arginosuccinate synthase K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 529.0
TH2_k127_8382448_1 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003385 240.0
TH2_k127_8382448_2 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000009722 88.0
TH2_k127_8405762_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 2.474e-224 710.0
TH2_k127_8405762_1 Dehydrogenase K00248 - 1.3.8.1 4.585e-198 634.0
TH2_k127_8405762_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 589.0
TH2_k127_8405762_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 518.0
TH2_k127_8405762_4 PFAM 2-nitropropane dioxygenase NPD K02371 - 1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 374.0
TH2_k127_8405762_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 346.0
TH2_k127_8405762_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 323.0
TH2_k127_8405762_7 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008614 282.0
TH2_k127_8405762_8 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000004551 55.0
TH2_k127_84211_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 541.0
TH2_k127_84211_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 538.0
TH2_k127_84211_2 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 310.0
TH2_k127_84211_3 PFAM transport-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001124 261.0
TH2_k127_84211_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000008771 237.0
TH2_k127_84211_5 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000003598 183.0
TH2_k127_84211_6 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000002087 178.0
TH2_k127_84211_7 peroxiredoxin activity - - - 0.000000000000000000000009416 108.0
TH2_k127_84211_8 PFAM Cyclic nucleotide-binding domain - - - 0.000000000001216 76.0
TH2_k127_84211_9 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000004471 67.0
TH2_k127_848671_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1140.0
TH2_k127_848671_1 Elongation factor Tu domain 2 K02355 - - 1.71e-270 848.0
TH2_k127_848671_2 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 475.0
TH2_k127_848671_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 445.0
TH2_k127_848671_4 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001209 265.0
TH2_k127_848671_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000004046 194.0
TH2_k127_848671_6 PFAM Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000001014 179.0
TH2_k127_848671_7 Amino acid permease - - - 0.0000000000000000000000000003997 115.0
TH2_k127_848671_8 Bacterial DNA-binding protein K03530 - - 0.000000000000000006975 87.0
TH2_k127_8489701_0 Pfam:Kce K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 387.0
TH2_k127_8489701_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 331.0
TH2_k127_8489701_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001538 284.0
TH2_k127_8489701_3 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000548 152.0
TH2_k127_8489701_4 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000004074 142.0
TH2_k127_8489701_5 Endonuclease containing a URI domain K07461 - - 0.000000000000000000002179 95.0
TH2_k127_8489701_7 - - - - 0.00002085 49.0
TH2_k127_8495041_0 HEAT repeats K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 547.0
TH2_k127_8495041_1 Aminotransferase class-V K00830,K00839 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 428.0
TH2_k127_8495041_10 Fe-S oxidoreductase - - - 0.00000000000002011 83.0
TH2_k127_8495041_11 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000002528 64.0
TH2_k127_8495041_2 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 423.0
TH2_k127_8495041_3 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000006084 265.0
TH2_k127_8495041_4 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000000000000000356 197.0
TH2_k127_8495041_5 Glycine cleavage system H protein K02437 - - 0.0000000000000000000000000000000000000000000000009825 177.0
TH2_k127_8495041_7 Protein of unknown function (DUF2283) - - - 0.000000000000000000005131 94.0
TH2_k127_8495041_8 Plasmid stabilization system K19092 - - 0.0000000000000000002572 87.0
TH2_k127_8495041_9 - - - - 0.000000000000000002378 85.0
TH2_k127_8575371_0 Carboxyl transferase domain - - - 3.591e-264 822.0
TH2_k127_8575371_1 DNA polymerase K02347 - - 1.96e-227 717.0
TH2_k127_8575371_10 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 395.0
TH2_k127_8575371_11 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 398.0
TH2_k127_8575371_12 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 383.0
TH2_k127_8575371_13 Belongs to the D-glutamate cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 361.0
TH2_k127_8575371_14 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 363.0
TH2_k127_8575371_15 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 346.0
TH2_k127_8575371_16 ACT domain K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 337.0
TH2_k127_8575371_17 Major Facilitator Superfamily K03535 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 322.0
TH2_k127_8575371_18 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 297.0
TH2_k127_8575371_19 RNA pseudouridylate synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 291.0
TH2_k127_8575371_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 2.498e-200 642.0
TH2_k127_8575371_20 PFAM Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006002 277.0
TH2_k127_8575371_21 PFAM Bile acid sodium symporter K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003478 263.0
TH2_k127_8575371_22 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000855 261.0
TH2_k127_8575371_23 - - - - 0.000000000000000000000000000000000000000000000000000000000001536 219.0
TH2_k127_8575371_24 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000676 205.0
TH2_k127_8575371_25 domain protein - - - 0.000000000000000000000000000000000000000000000000000000003775 217.0
TH2_k127_8575371_26 dextransucrase activity - - - 0.0000000000000000000000000000000000000000000000000007587 201.0
TH2_k127_8575371_27 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000005756 178.0
TH2_k127_8575371_28 Nitroreductase family - - - 0.000000000000000000000000000000000000000004204 163.0
TH2_k127_8575371_29 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000005234 159.0
TH2_k127_8575371_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.114e-198 646.0
TH2_k127_8575371_30 Protein of unknown function (DUF1016) - - - 0.000000000000000000000000000000000000001178 152.0
TH2_k127_8575371_31 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000001312 151.0
TH2_k127_8575371_32 Domain of unknown function (DUF4404) - - - 0.000000000000000000000000000000001146 132.0
TH2_k127_8575371_33 regulatory protein, FmdB family - - - 0.000000000000000000000000000000001313 132.0
TH2_k127_8575371_34 pfam nudix K03574 - 3.6.1.55 0.00000000000000000000000000000005233 130.0
TH2_k127_8575371_35 Nitroreductase family - - - 0.0000000000000000000000000000002969 134.0
TH2_k127_8575371_36 binding domain protein - - - 0.000000000000000000000000000004627 129.0
TH2_k127_8575371_37 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000004292 118.0
TH2_k127_8575371_38 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000006148 112.0
TH2_k127_8575371_39 sequence-specific DNA binding - - - 0.0000000000000000000421 95.0
TH2_k127_8575371_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 596.0
TH2_k127_8575371_40 aspartate kinase activity K00928,K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000002286 94.0
TH2_k127_8575371_41 - - - - 0.00000000000000003386 83.0
TH2_k127_8575371_42 - - - - 0.0000000000000001003 88.0
TH2_k127_8575371_43 toxin-antitoxin pair type II binding - - - 0.0000000000000007631 80.0
TH2_k127_8575371_44 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000009228 79.0
TH2_k127_8575371_45 ACT domain protein - - - 0.00000000000006905 77.0
TH2_k127_8575371_46 TRANSCRIPTIONal - - - 0.0000000002646 67.0
TH2_k127_8575371_47 - - - - 0.0000000004285 65.0
TH2_k127_8575371_48 reverse transcriptase - - - 0.00001506 47.0
TH2_k127_8575371_49 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0004016 49.0
TH2_k127_8575371_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 578.0
TH2_k127_8575371_6 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 561.0
TH2_k127_8575371_7 COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 505.0
TH2_k127_8575371_8 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 437.0
TH2_k127_8575371_9 MgtE intracellular - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 405.0
TH2_k127_8596911_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 574.0
TH2_k127_8596911_1 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 464.0
TH2_k127_8596911_2 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 385.0
TH2_k127_8596911_3 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000002472 175.0
TH2_k127_8596911_4 - - - - 0.0000000000000000000007656 96.0
TH2_k127_8596911_5 methyltransferase activity K00574,K12240,K18534,K19620,K20444 - 2.1.1.295,2.1.1.79 0.000000001622 61.0
TH2_k127_8600957_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1204.0
TH2_k127_8600957_1 Amino acid permease - - - 5.876e-282 878.0
TH2_k127_8600957_10 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 310.0
TH2_k127_8600957_11 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000001324 269.0
TH2_k127_8600957_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001982 264.0
TH2_k127_8600957_13 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002668 263.0
TH2_k127_8600957_14 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000008118 168.0
TH2_k127_8600957_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000009561 165.0
TH2_k127_8600957_16 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000001671 148.0
TH2_k127_8600957_17 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.000000000000000000000000000000003291 134.0
TH2_k127_8600957_2 Amino acid permease - - - 5.018e-279 869.0
TH2_k127_8600957_3 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 4.572e-217 694.0
TH2_k127_8600957_4 Cation transport protein K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 569.0
TH2_k127_8600957_5 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 377.0
TH2_k127_8600957_6 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 359.0
TH2_k127_8600957_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 336.0
TH2_k127_8600957_8 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 326.0
TH2_k127_8600957_9 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 308.0
TH2_k127_8611823_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001973 240.0
TH2_k127_8611823_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000516 142.0
TH2_k127_8611823_2 Domain of unknown function DUF11 - - - 0.0000000000005512 71.0
TH2_k127_8612802_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 366.0
TH2_k127_8612802_1 protein trimerization - - - 0.0000000000000000000000000000000000000000000007379 188.0
TH2_k127_8612802_2 energy transducer activity K03832,K08086 - - 0.00000000000000000000005164 109.0
TH2_k127_8612802_3 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000472 69.0
TH2_k127_8612802_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000000000006677 72.0
TH2_k127_8626862_0 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' - - - 0.0000000000000000000000000000000000000000000000000000000000000000006874 245.0
TH2_k127_8626862_1 COG1651 Protein-disulfide isomerase K21990 - - 0.00000000000000000000000000000000002346 139.0
TH2_k127_893950_0 -O-antigen - - - 0.0 1317.0
TH2_k127_893950_1 Transglutaminase-like - - - 2.924e-264 833.0
TH2_k127_893950_10 PFAM acyltransferase 3 - - - 0.0003509 52.0
TH2_k127_893950_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 619.0
TH2_k127_893950_3 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007262 277.0
TH2_k127_893950_4 serine-type peptidase activity K01278,K06889 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000001956 250.0
TH2_k127_893950_5 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000000000000000000002735 210.0
TH2_k127_893950_6 - - - - 0.00000000000000000000000000000000000003855 151.0
TH2_k127_893950_7 deacetylase - - - 0.0000000000000000000000000003695 126.0
TH2_k127_893950_9 - - - - 0.00002116 50.0
TH2_k127_942664_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 2.086e-211 674.0
TH2_k127_942664_1 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 323.0
TH2_k127_942664_2 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000006202 208.0
TH2_k127_946117_0 Glutamine amidotransferase domain K00764 - 2.4.2.14 3.297e-245 763.0
TH2_k127_946117_1 Sigma-54 interaction domain K07714,K07715 - - 7.14e-218 683.0
TH2_k127_946117_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000009789 214.0
TH2_k127_946117_11 Methyltransferase K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000001884 189.0
TH2_k127_946117_12 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000001947 184.0
TH2_k127_946117_13 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000002608 159.0
TH2_k127_946117_14 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000009965 145.0
TH2_k127_946117_15 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000000000000000000001016 147.0
TH2_k127_946117_16 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.0000000000000000000000000000000004921 136.0
TH2_k127_946117_17 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000551 125.0
TH2_k127_946117_18 THIoesterase K18700 - 3.1.2.29 0.00000000000000000000000000003117 122.0
TH2_k127_946117_19 nuclear chromosome segregation - - - 0.000000000000000000000007795 112.0
TH2_k127_946117_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 556.0
TH2_k127_946117_20 aspartic-type endopeptidase activity K06985 - - 0.00000000000000000000001765 111.0
TH2_k127_946117_21 PFAM Rubrerythrin - - - 0.0000000000000000000182 97.0
TH2_k127_946117_22 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000001417 84.0
TH2_k127_946117_23 cheY-homologous receiver domain - - - 0.0000000000000001468 83.0
TH2_k127_946117_24 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000002082 83.0
TH2_k127_946117_25 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate - - - 0.0000000000145 69.0
TH2_k127_946117_27 L,D-transpeptidase catalytic domain - - - 0.00001619 56.0
TH2_k127_946117_28 Adenylate cyclase - - - 0.00001962 50.0
TH2_k127_946117_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 542.0
TH2_k127_946117_4 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 492.0
TH2_k127_946117_5 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009588 284.0
TH2_k127_946117_6 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003313 279.0
TH2_k127_946117_7 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003339 276.0
TH2_k127_946117_8 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005468 244.0
TH2_k127_946117_9 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000112 213.0
TH2_k127_949815_0 Required for chromosome condensation and partitioning K03529 - - 4.869e-215 710.0
TH2_k127_949815_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000008696 109.0