Overview

ID MAG03896
Name TH2_bin.14
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA6898
Genus UBA6898
Species
Assembly information
Completeness (%) 78.66
Contamination (%) 2.72
GC content (%) 49.0
N50 (bp) 10,423
Genome size (bp) 1,657,483

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1694

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1116815_0 Nitrate nitrite transporter K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 535.0
TH2_k127_1116815_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000005108 111.0
TH2_k127_1116815_2 Cyclic nucleotide-binding domain K21563 - - 0.0000000001229 67.0
TH2_k127_1130646_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 8.517e-247 784.0
TH2_k127_1130646_1 ferrous iron transmembrane transporter activity K04759 - - 0.0000000005569 61.0
TH2_k127_1140591_0 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 461.0
TH2_k127_1140591_1 Putative peptidoglycan binding domain K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 411.0
TH2_k127_1140591_2 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000001516 261.0
TH2_k127_1164096_0 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000001835 247.0
TH2_k127_1164096_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000004899 154.0
TH2_k127_1164096_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000004897 131.0
TH2_k127_1173393_0 phosphorelay signal transduction system K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 440.0
TH2_k127_1173393_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 334.0
TH2_k127_1173393_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000009936 223.0
TH2_k127_1173393_3 PFAM Transposase DDE domain - - - 0.000000000000001446 78.0
TH2_k127_1173393_4 PFAM Transposase DDE domain - - - 0.00000000000002637 75.0
TH2_k127_1173393_5 NapC/NirT cytochrome c family, N-terminal region - - - 0.0001075 47.0
TH2_k127_1182070_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1729.0
TH2_k127_1182070_1 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 542.0
TH2_k127_1182070_10 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000005345 149.0
TH2_k127_1182070_11 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000002594 133.0
TH2_k127_1182070_12 Histidine kinase - - - 0.00000000001934 68.0
TH2_k127_1182070_13 - - - - 0.000000007509 60.0
TH2_k127_1182070_2 PFAM phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 537.0
TH2_k127_1182070_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 514.0
TH2_k127_1182070_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 482.0
TH2_k127_1182070_5 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 381.0
TH2_k127_1182070_6 membrane K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 362.0
TH2_k127_1182070_7 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000003212 212.0
TH2_k127_1182070_8 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000000000004717 171.0
TH2_k127_1182070_9 protein with SCP PR1 domains - - - 0.000000000000000000000000000000000000000001063 170.0
TH2_k127_1224898_0 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 308.0
TH2_k127_1224898_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000002505 174.0
TH2_k127_1224898_2 His Kinase A (phosphoacceptor) domain - - - 0.00000007353 62.0
TH2_k127_12278_0 Unusual protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009914 298.0
TH2_k127_12278_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004914 259.0
TH2_k127_12278_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003004 261.0
TH2_k127_12278_3 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000000001716 229.0
TH2_k127_12278_4 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000005417 182.0
TH2_k127_12278_5 Universal stress protein - - - 0.000000000000000000000000004346 115.0
TH2_k127_1297782_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 5.05e-214 671.0
TH2_k127_1297782_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000006317 227.0
TH2_k127_1297782_2 ACT domain - - - 0.00000000000000000000000000000000000000000000000000003492 190.0
TH2_k127_131541_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 484.0
TH2_k127_131541_1 radical SAM domain protein - - - 0.000000000000000000000000002864 115.0
TH2_k127_131541_2 ABC1 family - - - 0.00000003555 61.0
TH2_k127_1334713_0 Protein conserved in bacteria - - - 1.376e-230 740.0
TH2_k127_1334713_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 602.0
TH2_k127_1334713_2 Tetratricopeptide repeat K05807 - - 0.00000000000001656 77.0
TH2_k127_1334713_3 TIGR00268 family K06864 - - 0.0000000006493 63.0
TH2_k127_1337132_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 8.563e-280 876.0
TH2_k127_1337132_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 531.0
TH2_k127_1337132_10 DoxX K15977 - - 0.000000000000000000000000000000000000000007174 158.0
TH2_k127_1337132_11 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000001009 130.0
TH2_k127_1337132_13 Peptidase family M23 - - - 0.000000005406 57.0
TH2_k127_1337132_15 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0002368 47.0
TH2_k127_1337132_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 426.0
TH2_k127_1337132_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 405.0
TH2_k127_1337132_4 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 387.0
TH2_k127_1337132_5 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 372.0
TH2_k127_1337132_6 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 319.0
TH2_k127_1337132_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000006871 244.0
TH2_k127_1337132_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000009651 202.0
TH2_k127_1337132_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000001896 162.0
TH2_k127_1351365_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 400.0
TH2_k127_1351365_1 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 394.0
TH2_k127_1351365_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001751 291.0
TH2_k127_1351365_3 Diguanylate cyclase - - - 0.0000000000000000000000001836 123.0
TH2_k127_1366348_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 288.0
TH2_k127_1366348_1 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000002384 148.0
TH2_k127_1366348_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.000000000002038 68.0
TH2_k127_1366348_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 GO:0000287,GO:0000966,GO:0000967,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008312,GO:0008995,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0017151,GO:0019222,GO:0019439,GO:0019899,GO:0022607,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034655,GO:0034660,GO:0042254,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043462,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0048519,GO:0050789,GO:0050790,GO:0051095,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902280 3.1.26.12 0.0000001056 61.0
TH2_k127_1408188_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 2.188e-271 860.0
TH2_k127_1408188_1 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 300.0
TH2_k127_1408188_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000007057 234.0
TH2_k127_1408188_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000001186 190.0
TH2_k127_1408188_4 - - - - 0.0000000000000002646 80.0
TH2_k127_14236_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 1.775e-250 787.0
TH2_k127_14236_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 3.88e-210 666.0
TH2_k127_14236_2 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 476.0
TH2_k127_14236_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 338.0
TH2_k127_14236_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000001528 175.0
TH2_k127_14236_5 Molybdopterin oxidoreductase Fe4S4 region K00123,K00367 - 1.17.1.9,1.7.7.2 0.0000000000000000000000000000000000000000005376 160.0
TH2_k127_14236_6 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000006973 130.0
TH2_k127_14236_7 Single-strand DNA-specific exonuclease, C terminal domain K07462 - - 0.0000000000000000000000000000008753 126.0
TH2_k127_14410_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000000000003901 200.0
TH2_k127_14410_1 ATPase, AAA superfamily K07133 - - 0.0000000000000000000182 97.0
TH2_k127_14410_2 positive regulation of growth - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000000000000001822 85.0
TH2_k127_1476562_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 403.0
TH2_k127_1476562_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 348.0
TH2_k127_1476562_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004327 276.0
TH2_k127_1476562_3 Chemotaxis protein CheC K03410 - - 0.0000000000000000000000000000000000000000000000000000000009616 207.0
TH2_k127_1476562_4 COG0698 Ribose 5-phosphate isomerase RpiB - - - 0.0000000000000000000000000000000000000000000000000007431 188.0
TH2_k127_1476562_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000165 178.0
TH2_k127_1476562_6 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.0000000000000000000002788 100.0
TH2_k127_1476562_7 Belongs to the helicase family. UvrD subfamily - - - 0.0000000000000004062 82.0
TH2_k127_1483447_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 319.0
TH2_k127_1483447_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 296.0
TH2_k127_1483447_2 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 297.0
TH2_k127_1483447_3 Maf-like protein K06287 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - 0.00000000000000000000000000000000000000000000000001776 186.0
TH2_k127_1483447_4 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000008302 183.0
TH2_k127_1483447_5 HI0933-like protein K07007 - - 0.0000000000000000000001186 97.0
TH2_k127_1483447_6 PFAM Rhodanese domain protein - - - 0.000000000003181 67.0
TH2_k127_152714_0 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 565.0
TH2_k127_152714_1 protein secretion K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 533.0
TH2_k127_152714_2 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 436.0
TH2_k127_152714_4 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000006397 105.0
TH2_k127_152714_5 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000007963 83.0
TH2_k127_1550118_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 323.0
TH2_k127_1550118_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001293 243.0
TH2_k127_1550118_2 - - - - 0.00000000000000000000000000000000000000000000181 170.0
TH2_k127_1550118_3 PIN domain - - - 0.0000000001101 63.0
TH2_k127_1571406_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 1.21e-266 844.0
TH2_k127_1571406_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 308.0
TH2_k127_1571406_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000001576 184.0
TH2_k127_1571406_3 cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.00000000000000000000000001546 115.0
TH2_k127_1571406_4 FixH - - - 0.00000000000000000000000001669 115.0
TH2_k127_1571406_5 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.000000000000000002093 86.0
TH2_k127_1571406_6 FixH - - - 0.0000000000001258 79.0
TH2_k127_1571406_7 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.00000000001411 69.0
TH2_k127_1582941_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 4.315e-217 681.0
TH2_k127_1582941_1 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000005225 248.0
TH2_k127_1582941_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000002233 235.0
TH2_k127_1582941_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000002115 171.0
TH2_k127_1582941_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000002878 94.0
TH2_k127_1591211_0 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 338.0
TH2_k127_1591211_1 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000006972 192.0
TH2_k127_1591211_2 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000002628 126.0
TH2_k127_1591211_3 Transmembrane secretion effector - - - 0.0000003526 53.0
TH2_k127_1596588_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 2.239e-226 730.0
TH2_k127_1596588_1 Di-haem cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 491.0
TH2_k127_1596588_2 PAS domain K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 462.0
TH2_k127_1596588_3 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 352.0
TH2_k127_1596588_4 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006163 287.0
TH2_k127_1596588_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000003874 175.0
TH2_k127_1596588_6 radical SAM domain protein - - - 0.000000000000000000000000000001804 133.0
TH2_k127_161317_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 498.0
TH2_k127_161317_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 415.0
TH2_k127_161317_2 shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000002052 143.0
TH2_k127_161317_3 Domain of unknown function (DUF3786) - - - 0.0000007615 54.0
TH2_k127_1617997_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 424.0
TH2_k127_1617997_1 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000149 286.0
TH2_k127_1617997_2 PFAM Outer membrane K06142 - - 0.00001261 54.0
TH2_k127_1627762_0 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000441 247.0
TH2_k127_1627762_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000003525 220.0
TH2_k127_1627762_2 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000336 193.0
TH2_k127_1627762_3 Ubiquinol--cytochrome c reductase - - - 0.0000000000000000000000000000000000000000000002872 169.0
TH2_k127_1627762_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000002409 68.0
TH2_k127_1662963_0 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 544.0
TH2_k127_1662963_1 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 293.0
TH2_k127_1662963_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001338 271.0
TH2_k127_1662963_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000007894 234.0
TH2_k127_1662963_4 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000004505 210.0
TH2_k127_1662963_5 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000003052 79.0
TH2_k127_1730728_0 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000000000000000000426 155.0
TH2_k127_1730728_1 Protein of unknown function (DUF2845) - - - 0.00000000000000000003841 94.0
TH2_k127_1730728_2 Chemotaxis sensory transducer K03406 - - 0.00003359 47.0
TH2_k127_1730728_3 Sporulation related domain - - - 0.0000897 53.0
TH2_k127_1797097_0 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00986,K15342 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 573.0
TH2_k127_1797097_1 Transposase K07491 - - 0.0000000000000000000000000000004847 125.0
TH2_k127_1797097_2 Protein conserved in bacteria - - - 0.00000000000000000000000000002133 119.0
TH2_k127_1797097_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000000000000002122 116.0
TH2_k127_1797097_4 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000002671 104.0
TH2_k127_1797097_5 Transposase IS200 like - - - 0.0000004734 52.0
TH2_k127_1797097_6 Transposase IS200 like K07491 - - 0.0000395 46.0
TH2_k127_1820291_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.7e-322 998.0
TH2_k127_1820291_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 363.0
TH2_k127_1820291_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000005112 87.0
TH2_k127_1820291_3 sulfur carrier activity K04085 - - 0.00000000000002991 76.0
TH2_k127_186838_0 40-residue yvtn family beta-propeller repeat protein - - - 1.293e-209 659.0
TH2_k127_186838_1 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 7.394e-202 644.0
TH2_k127_186838_10 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 340.0
TH2_k127_186838_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 320.0
TH2_k127_186838_12 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 319.0
TH2_k127_186838_13 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008479 283.0
TH2_k127_186838_14 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000008484 255.0
TH2_k127_186838_15 PFAM response regulator receiver K02483,K18344 - - 0.00000000000000000000000000000000000000000000000000000000000000000001462 240.0
TH2_k127_186838_16 phosphatidate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002009 237.0
TH2_k127_186838_17 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000006594 228.0
TH2_k127_186838_18 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000001067 175.0
TH2_k127_186838_19 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000000000000000000002106 167.0
TH2_k127_186838_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 531.0
TH2_k127_186838_20 RNA-binding protein containing a PIN domain K06962 - - 0.000000000000000000000000000000001143 136.0
TH2_k127_186838_21 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000005068 126.0
TH2_k127_186838_22 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000001485 134.0
TH2_k127_186838_23 OsmC-like protein - - - 0.0000000000000000001865 94.0
TH2_k127_186838_24 Belongs to the peptidase M48B family K03799 - - 0.000000000001025 69.0
TH2_k127_186838_25 - - - - 0.0000000002999 63.0
TH2_k127_186838_26 DUF167 - - - 0.0000000003111 64.0
TH2_k127_186838_27 Cell division protein FtsQ K03589 - - 0.0000004166 57.0
TH2_k127_186838_28 - - - - 0.00002835 50.0
TH2_k127_186838_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 495.0
TH2_k127_186838_4 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 451.0
TH2_k127_186838_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 395.0
TH2_k127_186838_6 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 372.0
TH2_k127_186838_7 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 364.0
TH2_k127_186838_8 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 358.0
TH2_k127_186838_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 347.0
TH2_k127_19296_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000006296 246.0
TH2_k127_19296_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000008895 207.0
TH2_k127_19296_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000373 152.0
TH2_k127_1931157_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.0000000000000000000000000000000000000000000000000000000000009358 218.0
TH2_k127_1931157_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000006325 85.0
TH2_k127_1931157_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000001421 61.0
TH2_k127_1936561_0 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 388.0
TH2_k127_1936561_1 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 317.0
TH2_k127_1936561_2 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002659 279.0
TH2_k127_1936561_3 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003033 259.0
TH2_k127_1936561_4 cell redox homeostasis - - - 0.000000000000000000000000000007043 119.0
TH2_k127_1936561_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000002336 97.0
TH2_k127_200696_0 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 311.0
TH2_k127_200696_1 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000001914 207.0
TH2_k127_200696_2 DGC domain - - - 0.000000000000000000000000000000000000000000000000000000006925 203.0
TH2_k127_200696_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000008011 178.0
TH2_k127_2023920_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.875e-270 847.0
TH2_k127_2023920_1 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 9.49e-220 693.0
TH2_k127_2023920_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 568.0
TH2_k127_2023920_3 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 372.0
TH2_k127_2023920_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 325.0
TH2_k127_2023920_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001793 243.0
TH2_k127_2023920_6 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000001926 204.0
TH2_k127_2023920_7 Domain of unknown function (DUF3842) - - - 0.000000000000000000000000000000000000000000000000001074 187.0
TH2_k127_2023920_8 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000000002672 171.0
TH2_k127_2023920_9 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000001535 111.0
TH2_k127_2048135_0 MMPL family K07003 - - 0.000000000000000000000000000001167 141.0
TH2_k127_2048135_1 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000002182 98.0
TH2_k127_2048135_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000005701 84.0
TH2_k127_2048135_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000001106 76.0
TH2_k127_2048135_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000002398 76.0
TH2_k127_2132489_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.857e-313 983.0
TH2_k127_2132489_1 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 559.0
TH2_k127_2132489_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 498.0
TH2_k127_2132489_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 500.0
TH2_k127_2132489_4 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 442.0
TH2_k127_2132489_5 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005259 270.0
TH2_k127_2132489_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000001287 220.0
TH2_k127_2132489_7 ATP synthase, subunit b - - - 0.0000003572 56.0
TH2_k127_2132489_8 RecX family K03565 - - 0.0000898 51.0
TH2_k127_2132489_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0005303 44.0
TH2_k127_2140876_0 Proton-conducting membrane transporter - - - 7.736e-199 631.0
TH2_k127_2140876_1 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 460.0
TH2_k127_2140876_2 HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide K12138,K12139,K15829 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 331.0
TH2_k127_2140876_3 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002497 244.0
TH2_k127_2140876_4 PFAM NADH Ubiquinone - - - 0.0000000000000000000000000000000000000000000000000000000000000005755 227.0
TH2_k127_2140876_5 Proton-conducting membrane transporter - - - 0.00000000003746 66.0
TH2_k127_2140876_7 - - - - 0.00003872 46.0
TH2_k127_218101_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 8.258e-264 824.0
TH2_k127_218101_1 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 323.0
TH2_k127_218101_2 protein-disulfide reductase activity - - - 0.0000000000000000000002454 100.0
TH2_k127_218101_3 indolepyruvate ferredoxin oxidoreductase beta subunit K00180 - 1.2.7.8 0.000000000001617 70.0
TH2_k127_2289774_0 Conserved carboxylase domain K01958 - 6.4.1.1 0.0 1025.0
TH2_k127_2289774_1 acetyl-CoA carboxylase, biotin carboxylase K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 1.524e-249 777.0
TH2_k127_2289774_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000005969 245.0
TH2_k127_2289774_3 Evidence 2b Function of strongly homologous gene - - - 0.0000007452 50.0
TH2_k127_2332431_0 Histidine kinase - - - 1.179e-195 651.0
TH2_k127_2332431_1 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 297.0
TH2_k127_2332431_2 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000001043 232.0
TH2_k127_2332431_3 PFAM Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000157 241.0
TH2_k127_2332431_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000002975 131.0
TH2_k127_2370396_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 598.0
TH2_k127_2370396_1 NADH-quinone oxidoreductase K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 534.0
TH2_k127_2370396_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 449.0
TH2_k127_2371624_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 346.0
TH2_k127_2371624_1 PFAM HhH-GPD family protein K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 321.0
TH2_k127_2371624_11 Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.0004677 50.0
TH2_k127_2371624_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 323.0
TH2_k127_2371624_3 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000032 293.0
TH2_k127_2371624_4 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000001474 236.0
TH2_k127_2371624_5 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000001381 150.0
TH2_k127_2371624_6 - - - - 0.0000000000000007121 82.0
TH2_k127_2371624_8 Chemotaxis phosphatase CheX - - - 0.00000000000002048 81.0
TH2_k127_2380673_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 394.0
TH2_k127_2380673_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000001908 237.0
TH2_k127_2380673_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000008714 149.0
TH2_k127_2380673_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.0005401 43.0
TH2_k127_2388574_0 Transposase zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 373.0
TH2_k127_2388574_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 349.0
TH2_k127_2388574_2 WYL domain K13573 - - 0.000000000000000001925 92.0
TH2_k127_2464229_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 4.263e-290 902.0
TH2_k127_2464229_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 614.0
TH2_k127_2464229_10 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 377.0
TH2_k127_2464229_11 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 340.0
TH2_k127_2464229_12 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 338.0
TH2_k127_2464229_13 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003786 285.0
TH2_k127_2464229_14 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000001107 264.0
TH2_k127_2464229_15 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000002173 258.0
TH2_k127_2464229_16 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000257 250.0
TH2_k127_2464229_17 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000319 225.0
TH2_k127_2464229_18 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000002352 220.0
TH2_k127_2464229_19 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000002681 230.0
TH2_k127_2464229_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 577.0
TH2_k127_2464229_20 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000003713 201.0
TH2_k127_2464229_21 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000003827 195.0
TH2_k127_2464229_22 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000003919 201.0
TH2_k127_2464229_23 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000009402 183.0
TH2_k127_2464229_24 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000001115 178.0
TH2_k127_2464229_25 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000001837 171.0
TH2_k127_2464229_26 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000007078 169.0
TH2_k127_2464229_27 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000002326 172.0
TH2_k127_2464229_28 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000001986 164.0
TH2_k127_2464229_29 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.000000000000000000000000000000000000001808 150.0
TH2_k127_2464229_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 576.0
TH2_k127_2464229_30 Crossover junction endodeoxyribonuclease RuvC K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000006443 141.0
TH2_k127_2464229_31 Member of a two-component regulatory system K07644 - 2.7.13.3 0.00000000000000000000000000003466 131.0
TH2_k127_2464229_33 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000001678 114.0
TH2_k127_2464229_34 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000001437 103.0
TH2_k127_2464229_35 Protein of unknown function (DUF2905) - - - 0.0000000000000001869 81.0
TH2_k127_2464229_36 PFAM DsrE DsrF-like family - - - 0.0000000005706 65.0
TH2_k127_2464229_37 - K06871,K09858 - - 0.000000009988 59.0
TH2_k127_2464229_39 Sporulation related domain - - - 0.0000013 58.0
TH2_k127_2464229_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 475.0
TH2_k127_2464229_40 Protein of unknown function DUF134 - - - 0.00006371 46.0
TH2_k127_2464229_41 Protein of unknown function DUF134 - - - 0.0001242 44.0
TH2_k127_2464229_5 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 482.0
TH2_k127_2464229_6 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 467.0
TH2_k127_2464229_7 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 425.0
TH2_k127_2464229_8 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 421.0
TH2_k127_2464229_9 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 398.0
TH2_k127_2474658_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1114.0
TH2_k127_2474658_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 384.0
TH2_k127_2483181_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.742e-207 652.0
TH2_k127_2483181_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 496.0
TH2_k127_2483181_10 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000002528 201.0
TH2_k127_2483181_11 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001682 199.0
TH2_k127_2483181_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000004997 198.0
TH2_k127_2483181_13 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001482 183.0
TH2_k127_2483181_14 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000007517 181.0
TH2_k127_2483181_15 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000297 159.0
TH2_k127_2483181_16 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000007689 154.0
TH2_k127_2483181_17 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000006061 133.0
TH2_k127_2483181_18 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000001206 130.0
TH2_k127_2483181_19 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000009355 106.0
TH2_k127_2483181_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 352.0
TH2_k127_2483181_20 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000001143 105.0
TH2_k127_2483181_21 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000002646 80.0
TH2_k127_2483181_22 Ribosomal protein L36 K02919 - - 0.00000000000001949 72.0
TH2_k127_2483181_23 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000004198 72.0
TH2_k127_2483181_24 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.000002082 56.0
TH2_k127_2483181_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 334.0
TH2_k127_2483181_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 315.0
TH2_k127_2483181_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 281.0
TH2_k127_2483181_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004407 276.0
TH2_k127_2483181_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000002526 231.0
TH2_k127_2483181_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000002656 228.0
TH2_k127_2483181_9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000004742 212.0
TH2_k127_2496574_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 7.683e-277 865.0
TH2_k127_2496574_1 General secretory system II, protein E domain protein K02652 - - 2.5e-214 682.0
TH2_k127_2496574_2 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 537.0
TH2_k127_2496574_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 528.0
TH2_k127_2496574_4 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 372.0
TH2_k127_2496574_5 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005098 266.0
TH2_k127_2496574_6 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.000000000000000000000000000000000000001696 152.0
TH2_k127_2496574_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000003579 109.0
TH2_k127_2496574_8 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000006946 110.0
TH2_k127_2498384_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 522.0
TH2_k127_2498384_1 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000004375 232.0
TH2_k127_2498384_2 Mo-molybdopterin cofactor metabolic process K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000004086 228.0
TH2_k127_2498384_3 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000195 191.0
TH2_k127_250060_0 GTP-binding protein TypA K06207 - - 5.756e-270 843.0
TH2_k127_250060_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 493.0
TH2_k127_250060_2 sugar transferase K00996 - 2.7.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 422.0
TH2_k127_250060_3 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 379.0
TH2_k127_250060_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 358.0
TH2_k127_250060_5 Wzt C-terminal domain K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 308.0
TH2_k127_250060_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000006719 79.0
TH2_k127_250060_7 Methyltransferase domain - - - 0.00000008488 60.0
TH2_k127_2546444_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 5.201e-279 869.0
TH2_k127_2546444_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 535.0
TH2_k127_2546444_10 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000007695 132.0
TH2_k127_2546444_11 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.000000000000000000001082 103.0
TH2_k127_2546444_12 Two component signalling adaptor domain K03408 - - 0.00000000000000000008629 98.0
TH2_k127_2546444_13 phosphate K02040 - - 0.0000004094 57.0
TH2_k127_2546444_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 534.0
TH2_k127_2546444_3 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 373.0
TH2_k127_2546444_4 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 290.0
TH2_k127_2546444_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003239 306.0
TH2_k127_2546444_6 Pyridoxal-phosphate dependent enzyme K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000004275 246.0
TH2_k127_2546444_7 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000000000000005084 172.0
TH2_k127_2546444_8 Ferric uptake regulator family K09825 - - 0.0000000000000000000000000000000000000008231 152.0
TH2_k127_2546444_9 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000000000001004 147.0
TH2_k127_2583897_0 Heat shock 70 kDa protein K04043 - - 6.963e-318 982.0
TH2_k127_2583897_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.708e-224 699.0
TH2_k127_2583897_10 Chromate transporter K07240 - - 0.00000000000000000000000000000002661 133.0
TH2_k127_2583897_11 Chromate transporter K07240 - - 0.000000000000000000000000000004868 126.0
TH2_k127_2583897_12 PFAM aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000001878 118.0
TH2_k127_2583897_13 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000001331 99.0
TH2_k127_2583897_14 membrane K07058 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000003588 94.0
TH2_k127_2583897_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 438.0
TH2_k127_2583897_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 415.0
TH2_k127_2583897_4 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 364.0
TH2_k127_2583897_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 299.0
TH2_k127_2583897_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000001772 242.0
TH2_k127_2583897_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000004207 187.0
TH2_k127_2583897_8 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000002406 174.0
TH2_k127_2583897_9 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000007075 156.0
TH2_k127_2595169_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 293.0
TH2_k127_2595169_1 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001361 287.0
TH2_k127_2595169_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000006966 226.0
TH2_k127_2595169_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000005035 195.0
TH2_k127_2595169_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000009569 193.0
TH2_k127_2595169_5 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000002596 182.0
TH2_k127_2595169_6 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000001418 119.0
TH2_k127_2595169_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000009238 101.0
TH2_k127_2626196_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 480.0
TH2_k127_2626196_1 - - - - 0.000000000000000000000000000000000000000000000000000001821 196.0
TH2_k127_2626196_2 domain, Protein K00703,K07082 - 2.4.1.21 0.0000000000000000000000007222 112.0
TH2_k127_2653054_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 574.0
TH2_k127_2653054_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 443.0
TH2_k127_2653054_10 - - - - 0.000000000000000000000000000000000009222 137.0
TH2_k127_2653054_11 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000001479 78.0
TH2_k127_2653054_12 intermembrane phospholipid transfer K07323 - - 0.000000000000711 72.0
TH2_k127_2653054_13 Thiamine biosynthesis K03154 - - 0.000000000001865 70.0
TH2_k127_2653054_14 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000049 57.0
TH2_k127_2653054_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 338.0
TH2_k127_2653054_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 329.0
TH2_k127_2653054_4 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 314.0
TH2_k127_2653054_5 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001916 282.0
TH2_k127_2653054_6 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001092 271.0
TH2_k127_2653054_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000001228 213.0
TH2_k127_2653054_8 - - - - 0.00000000000000000000000000000000000000000000000000000005686 205.0
TH2_k127_2653054_9 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000003482 179.0
TH2_k127_2669195_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 551.0
TH2_k127_2669195_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 544.0
TH2_k127_2669195_10 - - - - 0.0000000000000000000000000000000000001372 148.0
TH2_k127_2669195_11 response regulator, receiver - - - 0.00000000000000000000000000000001469 146.0
TH2_k127_2669195_12 - - - - 0.0002039 47.0
TH2_k127_2669195_2 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 527.0
TH2_k127_2669195_3 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 409.0
TH2_k127_2669195_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 383.0
TH2_k127_2669195_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 348.0
TH2_k127_2669195_6 iron-sulfur transferase activity K07126,K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003882 266.0
TH2_k127_2669195_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001798 261.0
TH2_k127_2669195_8 ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002147 226.0
TH2_k127_2669195_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000002553 176.0
TH2_k127_2733972_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 3.877e-259 818.0
TH2_k127_2733972_1 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 323.0
TH2_k127_2733972_2 PFAM cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 311.0
TH2_k127_2733972_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000006897 155.0
TH2_k127_2733972_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000007569 83.0
TH2_k127_2733972_5 - - - - 0.0000000000002467 70.0
TH2_k127_2737783_0 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 535.0
TH2_k127_2737783_1 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 414.0
TH2_k127_2737783_10 Sulfurtransferase TusA - - - 0.0000000000000000000000002906 106.0
TH2_k127_2737783_11 Glutaredoxin K03676 - - 0.00000000000002401 73.0
TH2_k127_2737783_2 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 374.0
TH2_k127_2737783_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000002669 232.0
TH2_k127_2737783_4 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000007109 194.0
TH2_k127_2737783_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000002168 153.0
TH2_k127_2737783_6 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000009939 149.0
TH2_k127_2737783_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000001532 149.0
TH2_k127_2737783_8 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000000000000002956 151.0
TH2_k127_2737783_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000003011 147.0
TH2_k127_2776535_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000001579 198.0
TH2_k127_2776535_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000004294 200.0
TH2_k127_2776535_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000486 124.0
TH2_k127_2776535_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000007822 96.0
TH2_k127_2777067_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 360.0
TH2_k127_2777067_1 Carbohydrate-binding family 9 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 285.0
TH2_k127_2777067_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000009078 253.0
TH2_k127_2777067_3 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000003345 235.0
TH2_k127_2777067_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000001919 211.0
TH2_k127_2777067_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000001105 188.0
TH2_k127_2777067_6 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.000000000000000000000000000000000000000000003005 167.0
TH2_k127_2777067_7 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000133 158.0
TH2_k127_2777067_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000001015 131.0
TH2_k127_2777067_9 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000001849 81.0
TH2_k127_2778281_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 541.0
TH2_k127_2778281_1 Ecdysteroid kinase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 466.0
TH2_k127_2778281_10 NTPase - - - 0.0000000000000000000000000000000000003343 146.0
TH2_k127_2778281_11 Acetyltransferase (GNAT) family - - - 0.000002726 56.0
TH2_k127_2778281_2 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 387.0
TH2_k127_2778281_3 Chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 317.0
TH2_k127_2778281_4 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 314.0
TH2_k127_2778281_5 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 294.0
TH2_k127_2778281_6 ATP cone domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003901 258.0
TH2_k127_2778281_7 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000001848 239.0
TH2_k127_2778281_8 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000003817 218.0
TH2_k127_2778281_9 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000005461 189.0
TH2_k127_2790416_0 Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000006515 175.0
TH2_k127_2790416_1 Hpt domain - - - 0.00000000000000000000000000000000002474 143.0
TH2_k127_2790416_2 response regulator, receiver K03413 - - 0.000000000000000001659 92.0
TH2_k127_2790416_3 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000009754 76.0
TH2_k127_2790416_4 Cysteine-rich small domain K07162 - - 0.0000000000003683 70.0
TH2_k127_2790416_5 Multidrug transporter - - - 0.00000000003763 69.0
TH2_k127_2879090_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 594.0
TH2_k127_2879090_1 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000001376 221.0
TH2_k127_2879090_2 TIGRFAM amino acid adenylation domain - - - 0.00000000000000000000000000001057 128.0
TH2_k127_2911744_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 349.0
TH2_k127_2911744_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000009831 211.0
TH2_k127_2911744_2 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000000000000000002885 158.0
TH2_k127_2911744_3 - - - - 0.00000000000000000000000000000000004248 137.0
TH2_k127_2911744_4 4 iron, 4 sulfur cluster binding - - - 0.0000000007831 61.0
TH2_k127_2911744_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.00005823 51.0
TH2_k127_294173_0 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000003132 166.0
TH2_k127_294173_1 nuclease activity - - - 0.000000000000000000000000000000000000002482 149.0
TH2_k127_294173_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000004584 106.0
TH2_k127_294173_3 Protein of unknown function (DUF1156) K07445 - - 0.00000000000000000000001474 100.0
TH2_k127_294173_4 Antitoxin component of bacterial toxin-antitoxin system, MqsA K13655 - - 0.000000000000002391 78.0
TH2_k127_294173_5 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000002225 72.0
TH2_k127_2969355_0 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 327.0
TH2_k127_2969355_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000001906 151.0
TH2_k127_3014601_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 546.0
TH2_k127_3014601_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008451 278.0
TH2_k127_3014601_10 Histidine kinase K02482 - 2.7.13.3 0.000000000000002142 88.0
TH2_k127_3014601_11 ABC transporter substrate binding protein K01989 - - 0.00000000000002986 83.0
TH2_k127_3014601_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.0000000001218 66.0
TH2_k127_3014601_13 - - - - 0.0007743 49.0
TH2_k127_3014601_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006136 256.0
TH2_k127_3014601_3 Bacterial regulatory helix-turn-helix protein, lysR family K21900 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001851 252.0
TH2_k127_3014601_4 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000107 246.0
TH2_k127_3014601_5 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000001408 226.0
TH2_k127_3014601_6 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000003743 217.0
TH2_k127_3014601_7 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000001609 133.0
TH2_k127_3014601_8 FtsX-like permease family - - - 0.0000000000000000000000000000006124 128.0
TH2_k127_3014601_9 Thioredoxin-like - - - 0.0000000000000000001345 91.0
TH2_k127_3026138_0 PD-(D/E)XK nuclease superfamily - - - 3.614e-234 760.0
TH2_k127_3026138_1 Belongs to the helicase family. UvrD subfamily - - - 0.000000000000000000000000000000000000001195 156.0
TH2_k127_3051842_0 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 368.0
TH2_k127_3051842_1 PFAM ABC transporter related K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009907 270.0
TH2_k127_3051842_2 Phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000009716 236.0
TH2_k127_3051842_3 Belongs to the Fur family K02076,K03711 GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000001607 176.0
TH2_k127_3051842_4 pfam cbs - - - 0.0000000000000000008304 92.0
TH2_k127_3051842_5 ABC 3 transport family K09816 - - 0.00000000000000001398 86.0
TH2_k127_3076940_0 - - - - 0.00000000000000000009264 93.0
TH2_k127_3079221_0 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 486.0
TH2_k127_3079221_1 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009306 372.0
TH2_k127_3079221_2 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 356.0
TH2_k127_3079221_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000008497 168.0
TH2_k127_311528_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 505.0
TH2_k127_311528_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 476.0
TH2_k127_311528_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 446.0
TH2_k127_311528_3 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 416.0
TH2_k127_311528_4 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002182 265.0
TH2_k127_311528_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000005591 160.0
TH2_k127_3177030_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.296e-264 831.0
TH2_k127_3177030_1 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001111 250.0
TH2_k127_3184923_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 429.0
TH2_k127_3184923_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000001677 231.0
TH2_k127_3195957_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 3.555e-195 614.0
TH2_k127_3195957_1 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 463.0
TH2_k127_3195957_2 Protein of unknown function (DUF1456) - - - 0.0000000000000000000000000001546 116.0
TH2_k127_3195957_3 conserved protein (DUF2132) - - - 0.0000000000000000000004375 96.0
TH2_k127_3214596_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 340.0
TH2_k127_3214596_1 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002554 284.0
TH2_k127_3214596_2 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006964 273.0
TH2_k127_3221178_0 sensor diguanylate cyclase phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 485.0
TH2_k127_3221178_1 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 380.0
TH2_k127_3221178_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 301.0
TH2_k127_3221178_3 Response regulator, receiver K11443 - - 0.000000000000000000000000000000000000000000005169 166.0
TH2_k127_3221178_4 Helix-hairpin-helix motif - - - 0.000000000000000000000000000000000000000005059 161.0
TH2_k127_3221178_5 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000000009045 144.0
TH2_k127_3248678_0 Iron-sulfur cluster-binding domain K06871 - - 2.533e-217 681.0
TH2_k127_3248678_1 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000892 416.0
TH2_k127_3248678_10 Protein of unknown function (DUF433) - - - 0.00000000001345 66.0
TH2_k127_3248678_11 - - - - 0.000000001255 62.0
TH2_k127_3248678_13 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817,K04720 - 2.6.1.9,4.1.1.81 0.00006045 46.0
TH2_k127_3248678_2 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 370.0
TH2_k127_3248678_3 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 356.0
TH2_k127_3248678_4 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 325.0
TH2_k127_3248678_5 Metal-dependent phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000191 261.0
TH2_k127_3248678_6 PFAM Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000002633 249.0
TH2_k127_3248678_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000001542 177.0
TH2_k127_3248678_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000002433 179.0
TH2_k127_3248678_9 Glutathione peroxidase - - - 0.00000000000000000000000000000000001461 142.0
TH2_k127_3350961_0 PFAM Sulfatase - - - 2.715e-291 903.0
TH2_k127_3350961_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.384e-274 856.0
TH2_k127_3350961_2 Phosphoglycerate kinase K00927 - 2.7.2.3 6.203e-197 620.0
TH2_k127_3350961_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 482.0
TH2_k127_3350961_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008727 426.0
TH2_k127_3350961_5 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 362.0
TH2_k127_3350961_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000007965 256.0
TH2_k127_3350961_7 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000000000000000000612 158.0
TH2_k127_3350961_8 - - - - 0.0000000000000000000000000000002149 125.0
TH2_k127_3358066_0 Endoribonuclease that initiates mRNA decay K18682 - - 4.886e-208 659.0
TH2_k127_3358066_1 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 566.0
TH2_k127_3358066_2 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 516.0
TH2_k127_3358066_3 AAA ATPase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 466.0
TH2_k127_3358066_4 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 463.0
TH2_k127_3358066_5 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 323.0
TH2_k127_3358066_6 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000384 214.0
TH2_k127_3358066_7 Histidine kinase - - - 0.000000000000000000000000000000000000000388 157.0
TH2_k127_3358066_8 PFAM response regulator receiver - - - 0.00000000000000000000000000001398 123.0
TH2_k127_3375576_0 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 1.717e-204 642.0
TH2_k127_3375576_1 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 411.0
TH2_k127_3375576_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000001645 62.0
TH2_k127_3375576_2 PFAM peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 339.0
TH2_k127_3375576_3 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008242 246.0
TH2_k127_3375576_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000001571 195.0
TH2_k127_3375576_5 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000000001286 137.0
TH2_k127_3375576_6 electron transfer activity K00428 - 1.11.1.5 0.000000000000000000000009404 106.0
TH2_k127_3375576_7 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000001486 106.0
TH2_k127_3375576_8 - - - - 0.000000000000000009299 84.0
TH2_k127_3456968_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 613.0
TH2_k127_3456968_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 406.0
TH2_k127_3456968_2 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00003364 46.0
TH2_k127_3498288_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.305e-307 950.0
TH2_k127_3498288_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 259.0
TH2_k127_3498288_2 PFAM transposase IS111A IS1328 IS1533, transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000003977 134.0
TH2_k127_3540440_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 1.551e-307 956.0
TH2_k127_3540440_1 FAD dependent oxidoreductase K16885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 591.0
TH2_k127_3576828_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1100.0
TH2_k127_3576828_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 285.0
TH2_k127_3576828_3 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000008649 82.0
TH2_k127_3576828_4 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000003885 64.0
TH2_k127_3579107_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.93e-322 1006.0
TH2_k127_3579107_1 Molecular chaperone. Has ATPase activity K04079 - - 2.295e-287 894.0
TH2_k127_3579107_10 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000169 275.0
TH2_k127_3579107_11 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004996 275.0
TH2_k127_3579107_12 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000003373 250.0
TH2_k127_3579107_13 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000001654 248.0
TH2_k127_3579107_14 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000001564 247.0
TH2_k127_3579107_15 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000004671 242.0
TH2_k127_3579107_16 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000002359 209.0
TH2_k127_3579107_17 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000002892 187.0
TH2_k127_3579107_18 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000000006831 177.0
TH2_k127_3579107_19 LemA family K03744 - - 0.000000000000000000000000000000000000000000000004291 178.0
TH2_k127_3579107_2 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 1.609e-211 666.0
TH2_k127_3579107_20 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000004224 173.0
TH2_k127_3579107_21 SPTR Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000001222 167.0
TH2_k127_3579107_22 metalloendopeptidase activity K03799 - - 0.00000000000000000000000000000000000000002434 170.0
TH2_k127_3579107_23 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000007659 145.0
TH2_k127_3579107_24 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000000000000000000000000000004713 134.0
TH2_k127_3579107_25 peroxiredoxin activity - - - 0.0000000000000000000000000000002297 129.0
TH2_k127_3579107_26 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000005506 123.0
TH2_k127_3579107_27 RNase H - - - 0.0000000000000000000000000004166 124.0
TH2_k127_3579107_28 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000165 115.0
TH2_k127_3579107_29 anti-sigma regulatory factor K04757 - 2.7.11.1 0.0000000000000000000000001756 110.0
TH2_k127_3579107_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 616.0
TH2_k127_3579107_30 PFAM amidohydrolase - - - 0.0000000000000000000000005139 117.0
TH2_k127_3579107_31 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000199 105.0
TH2_k127_3579107_32 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000003934 102.0
TH2_k127_3579107_33 PFAM Rubredoxin-type Fe(Cys)4 protein K05297 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0017144,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114,GO:0072592 1.18.1.1 0.00000000000000000000006344 98.0
TH2_k127_3579107_34 NusG domain II K00805 - 2.5.1.30 0.00000000000000000007335 93.0
TH2_k127_3579107_35 antisigma factor binding K04749 - - 0.00000000000000000177 89.0
TH2_k127_3579107_36 cheY-homologous receiver domain - - - 0.000000000000000002184 91.0
TH2_k127_3579107_37 Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000007646 88.0
TH2_k127_3579107_38 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000008889 72.0
TH2_k127_3579107_39 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.0000000000003664 79.0
TH2_k127_3579107_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 462.0
TH2_k127_3579107_40 - - - - 0.0000000000004809 71.0
TH2_k127_3579107_41 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000002129 67.0
TH2_k127_3579107_42 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191 - - 0.000000007235 59.0
TH2_k127_3579107_43 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000002181 55.0
TH2_k127_3579107_44 PFAM Rhodanese domain protein - - - 0.000005166 48.0
TH2_k127_3579107_5 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 375.0
TH2_k127_3579107_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 362.0
TH2_k127_3579107_7 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 356.0
TH2_k127_3579107_8 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 348.0
TH2_k127_3579107_9 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 306.0
TH2_k127_3589603_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 530.0
TH2_k127_3589603_1 HPr kinase - - - 0.00000000000000000000000001287 121.0
TH2_k127_3589603_2 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000003175 100.0
TH2_k127_3589603_3 - - - - 0.000000002054 65.0
TH2_k127_3589603_4 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00001976 48.0
TH2_k127_3591951_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 370.0
TH2_k127_3591951_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 339.0
TH2_k127_3591951_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000012 125.0
TH2_k127_3591951_11 Protein of unknown function (DUF507) - - - 0.000000000000000000000000002716 113.0
TH2_k127_3591951_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000006876 108.0
TH2_k127_3591951_13 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000001234 110.0
TH2_k127_3591951_14 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000004343 104.0
TH2_k127_3591951_15 Glutathionylspermidine synthase preATP-grasp - - - 0.00000000000000000000003748 101.0
TH2_k127_3591951_16 Protein of unknown function (DUF507) - - - 0.0000000000000000000002454 100.0
TH2_k127_3591951_17 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000002956 71.0
TH2_k127_3591951_18 Acetyltransferase (GNAT) family K03824 - - 0.0000879 45.0
TH2_k127_3591951_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000642 236.0
TH2_k127_3591951_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000001258 245.0
TH2_k127_3591951_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000001155 233.0
TH2_k127_3591951_5 - - - - 0.000000000000000000000000000000000000000000000000000000008299 207.0
TH2_k127_3591951_6 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000009225 156.0
TH2_k127_3591951_7 SMART HNH nuclease K07451 - - 0.00000000000000000000000000000000000006019 144.0
TH2_k127_3591951_8 Domain of Unknown Function (DUF350) K08989 - - 0.0000000000000000000000000000000001121 138.0
TH2_k127_3591951_9 thiolester hydrolase activity - - - 0.0000000000000000000000000000006507 126.0
TH2_k127_361816_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.529e-211 662.0
TH2_k127_361816_1 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008546 285.0
TH2_k127_361816_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000001863 199.0
TH2_k127_361816_4 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000000000001552 114.0
TH2_k127_3646566_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 449.0
TH2_k127_3646566_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000003812 209.0
TH2_k127_3646566_2 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000001018 174.0
TH2_k127_3656082_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.601e-315 980.0
TH2_k127_3656082_1 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 1.203e-239 757.0
TH2_k127_3656082_10 Evidence 4 Homologs of previously reported genes of - - - 0.00000000004885 65.0
TH2_k127_3656082_2 GAF domain - - - 1.08e-216 693.0
TH2_k127_3656082_3 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007651 346.0
TH2_k127_3656082_4 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002026 261.0
TH2_k127_3656082_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000006235 248.0
TH2_k127_3656082_6 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000006636 189.0
TH2_k127_3656082_7 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000001387 162.0
TH2_k127_3656082_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000003373 130.0
TH2_k127_3656082_9 Ubiquinol--cytochrome c reductase - - - 0.00000000000000000000000000001421 118.0
TH2_k127_3667419_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 9.437e-298 934.0
TH2_k127_3667419_1 C-terminal, D2-small domain, of ClpB protein K03694 - - 8.726e-281 881.0
TH2_k127_3667419_10 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002744 276.0
TH2_k127_3667419_11 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007697 292.0
TH2_k127_3667419_12 Male sterility protein K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002529 273.0
TH2_k127_3667419_13 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009947 264.0
TH2_k127_3667419_14 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000004847 231.0
TH2_k127_3667419_15 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000001409 182.0
TH2_k127_3667419_16 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000002458 181.0
TH2_k127_3667419_17 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000273 164.0
TH2_k127_3667419_18 - - - - 0.00000000000000000000000000000000000000009619 173.0
TH2_k127_3667419_19 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.000000000000000000000000000003703 122.0
TH2_k127_3667419_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.64e-199 627.0
TH2_k127_3667419_20 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000002274 132.0
TH2_k127_3667419_21 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000001144 123.0
TH2_k127_3667419_22 DUF218 domain - - - 0.000000000000000003284 93.0
TH2_k127_3667419_23 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.0000000001329 64.0
TH2_k127_3667419_24 CoA binding domain K01905 - 6.2.1.13 0.00004721 48.0
TH2_k127_3667419_3 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 610.0
TH2_k127_3667419_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 410.0
TH2_k127_3667419_5 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 393.0
TH2_k127_3667419_6 PFAM Class II aldolase K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 357.0
TH2_k127_3667419_7 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 336.0
TH2_k127_3667419_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 319.0
TH2_k127_3667419_9 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 319.0
TH2_k127_3730745_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1191.0
TH2_k127_3730745_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 1.168e-216 677.0
TH2_k127_3730745_10 NIL - - - 0.000000000000000000000000002066 112.0
TH2_k127_3730745_11 ubiE/COQ5 methyltransferase family - - - 0.00000000001343 72.0
TH2_k127_3730745_12 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000001435 66.0
TH2_k127_3730745_13 COG2200 FOG EAL domain K20963 - 3.1.4.52 0.00000006845 61.0
TH2_k127_3730745_2 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 516.0
TH2_k127_3730745_3 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 302.0
TH2_k127_3730745_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 300.0
TH2_k127_3730745_5 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 290.0
TH2_k127_3730745_6 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 285.0
TH2_k127_3730745_7 PFAM Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001506 255.0
TH2_k127_3730745_8 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000004352 167.0
TH2_k127_3730745_9 ThiS family K03636 - - 0.000000000000000000000000000000001029 132.0
TH2_k127_375906_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.219e-226 712.0
TH2_k127_375906_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 7.045e-204 655.0
TH2_k127_375906_10 Thioredoxin K03672 - 1.8.1.8 0.00006845 52.0
TH2_k127_375906_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 546.0
TH2_k127_375906_3 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 544.0
TH2_k127_375906_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 391.0
TH2_k127_375906_5 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 353.0
TH2_k127_375906_6 zinc ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004481 258.0
TH2_k127_375906_7 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000007911 141.0
TH2_k127_375906_8 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000008463 129.0
TH2_k127_375906_9 Tetratricopeptide repeat-like domain - - - 0.00000000000000001217 91.0
TH2_k127_3762580_0 ABC transporter K06020 - 3.6.3.25 1.049e-308 951.0
TH2_k127_3762580_1 Putative Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 339.0
TH2_k127_3762580_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 309.0
TH2_k127_3762580_3 Large family of predicted nucleotide-binding domains K07175 - - 0.00000000000000000000000001655 111.0
TH2_k127_3792778_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1105.0
TH2_k127_3792778_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 7.074e-229 724.0
TH2_k127_3792778_10 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001538 187.0
TH2_k127_3792778_11 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000375 136.0
TH2_k127_3792778_12 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000006394 106.0
TH2_k127_3792778_13 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.000000000001955 79.0
TH2_k127_3792778_14 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00005748 53.0
TH2_k127_3792778_2 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 4.484e-211 675.0
TH2_k127_3792778_3 Ftsk_gamma K03466 - - 3.01e-196 634.0
TH2_k127_3792778_4 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 583.0
TH2_k127_3792778_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 408.0
TH2_k127_3792778_6 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 353.0
TH2_k127_3792778_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002282 283.0
TH2_k127_3792778_8 pyridoxamine 5-phosphate oxidase-related K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000002269 235.0
TH2_k127_3792778_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.0000000000000000000000000000000000000000000000000005401 190.0
TH2_k127_3834382_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1371.0
TH2_k127_3834382_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 342.0
TH2_k127_3834382_2 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000003239 85.0
TH2_k127_3855006_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 5.198e-237 741.0
TH2_k127_3855006_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 538.0
TH2_k127_3855006_10 HupF/HypC family K04653 - - 0.0000000000000000008849 89.0
TH2_k127_3855006_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 477.0
TH2_k127_3855006_3 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 393.0
TH2_k127_3855006_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 385.0
TH2_k127_3855006_5 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009327 266.0
TH2_k127_3855006_6 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000006038 187.0
TH2_k127_3855006_7 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000000000001244 180.0
TH2_k127_3855006_8 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000001954 157.0
TH2_k127_3855006_9 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000001604 129.0
TH2_k127_391785_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 507.0
TH2_k127_391785_1 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 321.0
TH2_k127_391785_2 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000007498 213.0
TH2_k127_391785_3 Belongs to the glycosyl hydrolase family 6 K03832 - - 0.0000000000002344 70.0
TH2_k127_4000498_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 570.0
TH2_k127_4000498_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 539.0
TH2_k127_4000498_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000009647 203.0
TH2_k127_4000498_3 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000000000002439 163.0
TH2_k127_4117182_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 2.016e-198 639.0
TH2_k127_4117182_1 HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide K12138,K12139,K15829 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 335.0
TH2_k127_4117182_2 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003153 245.0
TH2_k127_4117182_3 Helix-turn-helix domain K02806 - - 0.000000000000000000000000000000001332 138.0
TH2_k127_4117182_4 Transport permease protein K01992 - - 0.00002173 48.0
TH2_k127_4160188_0 PFAM UvrD REP helicase K03656,K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 598.0
TH2_k127_4160188_1 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000001254 213.0
TH2_k127_4160188_2 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000001232 147.0
TH2_k127_4160188_3 lyase activity - - - 0.0000000000000000001443 93.0
TH2_k127_4160188_4 - - - - 0.0000000000000000401 86.0
TH2_k127_4211914_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 520.0
TH2_k127_4211914_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 416.0
TH2_k127_4211914_10 - - - - 0.00000000000006527 74.0
TH2_k127_4211914_11 bacterial-type flagellum-dependent cell motility - - - 0.0000000002994 67.0
TH2_k127_4211914_12 Putative addiction module component - - - 0.00002533 48.0
TH2_k127_4211914_2 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 366.0
TH2_k127_4211914_3 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 367.0
TH2_k127_4211914_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000002259 241.0
TH2_k127_4211914_5 SMART Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.00000000000000000000000000007532 120.0
TH2_k127_4211914_6 Plasmid stabilization system - - - 0.000000000000000000000005414 102.0
TH2_k127_4211914_7 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000001569 98.0
TH2_k127_4211914_8 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000006038 85.0
TH2_k127_4211914_9 PFAM YcfA-like protein - - - 0.0000000000000002671 78.0
TH2_k127_4232647_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 3.113e-236 739.0
TH2_k127_4232647_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 8.875e-225 706.0
TH2_k127_4232647_2 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 317.0
TH2_k127_4232647_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000008672 105.0
TH2_k127_432082_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 410.0
TH2_k127_432082_1 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 339.0
TH2_k127_432082_2 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 327.0
TH2_k127_432082_3 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000003258 203.0
TH2_k127_432082_4 Domain of unknown function (DUF4388) - - - 0.000000000000000000000244 111.0
TH2_k127_432082_5 heat shock protein binding - - - 0.00000003164 66.0
TH2_k127_432082_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000006245 49.0
TH2_k127_4396113_0 GTP-binding protein TypA K06207 - - 7.806e-266 831.0
TH2_k127_4396113_1 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 321.0
TH2_k127_4396113_2 thiosulfate sulfurtransferase activity - - - 0.00001155 48.0
TH2_k127_4396113_3 Helix-turn-helix XRE-family like proteins K21498 - - 0.000786 45.0
TH2_k127_4462679_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 4.876e-286 894.0
TH2_k127_4462679_1 Psort location Cytoplasmic, score K07137 - - 5.399e-217 683.0
TH2_k127_4462679_10 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.00004721 48.0
TH2_k127_4462679_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 496.0
TH2_k127_4462679_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 410.0
TH2_k127_4462679_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000009666 258.0
TH2_k127_4462679_5 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000002189 207.0
TH2_k127_4462679_6 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000003891 173.0
TH2_k127_4462679_7 TIGRFAM 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000000000000000000001082 116.0
TH2_k127_4462679_8 Phospholipid methyltransferase - - - 0.000001232 50.0
TH2_k127_4462679_9 - - - - 0.000006978 48.0
TH2_k127_4473347_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 348.0
TH2_k127_4473347_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007945 274.0
TH2_k127_4473347_2 DEAD DEAH box helicase K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001192 255.0
TH2_k127_4473347_3 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000002501 175.0
TH2_k127_4473347_4 - - - - 0.000000000000000000000000000000000000001464 157.0
TH2_k127_4473347_5 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000005244 99.0
TH2_k127_4473347_6 S4 domain K14761 - - 0.000000000000000005855 85.0
TH2_k127_447840_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 437.0
TH2_k127_447840_1 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 300.0
TH2_k127_447840_2 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.000000000000000000001067 109.0
TH2_k127_4497099_0 Elongation factor G, domain IV K02355 - - 3.929e-294 917.0
TH2_k127_4497099_1 isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 284.0
TH2_k127_4497099_10 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.0000000005747 64.0
TH2_k127_4497099_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000005499 240.0
TH2_k127_4497099_3 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000001458 229.0
TH2_k127_4497099_4 - - - - 0.000000000000000000000000000000000000000000005891 166.0
TH2_k127_4497099_5 Cytochrome P460 - - - 0.00000000000000000000000000000000000000003306 158.0
TH2_k127_4497099_6 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000001238 163.0
TH2_k127_4497099_7 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000000000005948 119.0
TH2_k127_4497099_8 Cold shock K03704 - - 0.0000000000000000000000003721 106.0
TH2_k127_4497099_9 - - - - 0.00000000000000001087 85.0
TH2_k127_4615338_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2076.0
TH2_k127_4615338_1 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 537.0
TH2_k127_4615338_2 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000004513 166.0
TH2_k127_4615338_3 - - - - 0.00000000000000000000013 102.0
TH2_k127_4615338_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000107 56.0
TH2_k127_4615338_5 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000707 55.0
TH2_k127_4627781_0 cobalamin synthesis protein, P47K - - - 0.000000000000000000000000000000000000000000004383 175.0
TH2_k127_4627781_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000001348 161.0
TH2_k127_4627781_2 Acyltransferase family - - - 0.00000000000000000000000000000000000005409 156.0
TH2_k127_4627781_3 OsmC-like protein - - - 0.00000000000000000208 94.0
TH2_k127_4627781_4 regulation of RNA biosynthetic process - - - 0.000000000000003353 79.0
TH2_k127_4627781_5 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000008112 78.0
TH2_k127_4627781_6 Crp-like helix-turn-helix domain - - - 0.00000000000335 76.0
TH2_k127_4627781_7 Chemotaxis sensory transducer K03406 - - 0.0000000001754 65.0
TH2_k127_4627781_8 DNA-binding response regulator - - - 0.0000008969 51.0
TH2_k127_4627781_9 PFAM response regulator receiver - - - 0.0002532 48.0
TH2_k127_4645_0 General secretory system II, protein E domain protein K02652 - - 2.651e-213 679.0
TH2_k127_4645_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 552.0
TH2_k127_4645_2 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 379.0
TH2_k127_4645_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000007543 231.0
TH2_k127_4645_4 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.00000000000000000000000000000000000000001728 156.0
TH2_k127_4645_5 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000006652 153.0
TH2_k127_4645_6 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000004623 108.0
TH2_k127_4651133_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 5.253e-218 689.0
TH2_k127_4651133_1 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 499.0
TH2_k127_4651133_10 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000004503 130.0
TH2_k127_4651133_11 Protein of unknown function (DUF5131) - - - 0.0000000000000000000000000002665 115.0
TH2_k127_4651133_12 - - - - 0.000000000000000000000001119 109.0
TH2_k127_4651133_13 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000005302 87.0
TH2_k127_4651133_14 PIN domain - - - 0.00000000000000007564 86.0
TH2_k127_4651133_15 - - - - 0.000000000009785 66.0
TH2_k127_4651133_16 Transposase IS200 like - - - 0.0000003413 53.0
TH2_k127_4651133_17 DNA restriction-modification system - - - 0.000006976 50.0
TH2_k127_4651133_18 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0002999 44.0
TH2_k127_4651133_2 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 413.0
TH2_k127_4651133_3 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 409.0
TH2_k127_4651133_4 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002317 280.0
TH2_k127_4651133_5 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000003583 238.0
TH2_k127_4651133_6 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000002494 229.0
TH2_k127_4651133_7 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000003537 216.0
TH2_k127_4651133_8 Peptidase S24-like K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000005743 210.0
TH2_k127_4651133_9 Transposase - - - 0.000000000000000000000000000000001459 131.0
TH2_k127_4674744_0 all-trans-retinol 13,14-reductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 314.0
TH2_k127_4674744_1 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 311.0
TH2_k127_4674744_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000002613 170.0
TH2_k127_4674744_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000009904 158.0
TH2_k127_4687694_0 K transport systems K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 385.0
TH2_k127_4687694_1 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 296.0
TH2_k127_4687694_2 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002251 274.0
TH2_k127_4687694_3 Pfam:TPM K08988 - - 0.00000000000000000000000000000000000000000000000000029 192.0
TH2_k127_4687694_4 CHASE - - - 0.000000000000000000000000000000000005011 141.0
TH2_k127_4687694_5 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000001713 140.0
TH2_k127_4687694_6 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000002207 85.0
TH2_k127_4687694_7 - - - - 0.00000001208 60.0
TH2_k127_4714389_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 312.0
TH2_k127_4714389_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000002248 188.0
TH2_k127_4714389_3 Transcriptional regulator - - - 0.00000000000000000000000004584 111.0
TH2_k127_4714389_4 HEPN domain - - - 0.000000000000000000000002702 106.0
TH2_k127_4714389_5 - - - - 0.0000000000000000000004288 96.0
TH2_k127_4714389_6 Nucleotidyltransferase domain - - - 0.0000000000008865 73.0
TH2_k127_4714389_7 Mut7-C RNAse domain K00525 - 1.17.4.1 0.000000001481 62.0
TH2_k127_4714389_8 Glycosyltransferase like family 2 - - - 0.0000004463 52.0
TH2_k127_4714389_9 - - - - 0.0008835 45.0
TH2_k127_4726507_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 8.355e-234 730.0
TH2_k127_4726507_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 593.0
TH2_k127_4726507_2 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000011 244.0
TH2_k127_4726507_3 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000009661 234.0
TH2_k127_4726507_4 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000006536 194.0
TH2_k127_4726507_5 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000001291 184.0
TH2_k127_4726507_6 Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000002717 188.0
TH2_k127_4726507_7 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000006802 145.0
TH2_k127_4726507_8 RNA-binding protein - - - 0.000000000000000000000006392 104.0
TH2_k127_4735632_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 1.909e-266 832.0
TH2_k127_4735632_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 562.0
TH2_k127_4735632_10 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.00000000000000000000000000000000000000002323 157.0
TH2_k127_4735632_11 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.000000000000000000000000000000000000003115 151.0
TH2_k127_4735632_12 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000005436 144.0
TH2_k127_4735632_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000005319 140.0
TH2_k127_4735632_14 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000003631 131.0
TH2_k127_4735632_15 DRTGG domain - - - 0.00000000000000000000000000000006375 127.0
TH2_k127_4735632_16 phosphorelay signal transduction system K02437 - - 0.00000000000000000000000000003805 126.0
TH2_k127_4735632_17 PFAM DRTGG domain - - - 0.000000000000000000000000008251 115.0
TH2_k127_4735632_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000204 67.0
TH2_k127_4735632_19 PIN domain - - - 0.0000001401 57.0
TH2_k127_4735632_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 552.0
TH2_k127_4735632_3 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 526.0
TH2_k127_4735632_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 515.0
TH2_k127_4735632_5 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 346.0
TH2_k127_4735632_6 PHP-associated K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000007568 225.0
TH2_k127_4735632_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000003721 207.0
TH2_k127_4735632_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000006148 197.0
TH2_k127_4735632_9 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.0000000000000000000000000000000000000000000000000001171 198.0
TH2_k127_4756058_0 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 349.0
TH2_k127_4756058_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000004841 124.0
TH2_k127_4756058_2 PIN domain - - - 0.0000009429 53.0
TH2_k127_4756058_3 Cro/C1-type HTH DNA-binding domain - - - 0.000002233 57.0
TH2_k127_4778030_0 4Fe-4S dicluster domain - - - 2.119e-194 610.0
TH2_k127_4778030_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 428.0
TH2_k127_4778030_2 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 421.0
TH2_k127_4778030_3 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000000000000000003358 188.0
TH2_k127_4778030_4 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000000000000000000000000000002553 176.0
TH2_k127_4778030_5 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000001915 119.0
TH2_k127_4778030_6 lyase activity - - - 0.000000000000004661 80.0
TH2_k127_4844572_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.786e-311 972.0
TH2_k127_4844572_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 5.773e-259 821.0
TH2_k127_4844572_2 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 520.0
TH2_k127_4844572_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 485.0
TH2_k127_4844572_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 394.0
TH2_k127_4844572_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 345.0
TH2_k127_4858025_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.032e-252 791.0
TH2_k127_4858025_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.427e-218 702.0
TH2_k127_4858025_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 297.0
TH2_k127_4890183_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.939e-216 683.0
TH2_k127_4890183_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 595.0
TH2_k127_4922699_0 Histidine kinase - - - 2.412e-200 647.0
TH2_k127_4922699_1 Domains REC, sigma54 interaction, HTH8 K02481 - - 0.00000008929 53.0
TH2_k127_5014313_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000006879 186.0
TH2_k127_5014313_1 Caspase domain - - - 0.00000000000000006576 93.0
TH2_k127_5014313_2 Winged helix-turn helix - - - 0.000000004553 60.0
TH2_k127_5014313_3 COG COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.000003125 59.0
TH2_k127_5014313_4 Domain of unknown function (DUF4384) - - - 0.000007082 57.0
TH2_k127_5014313_5 - - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009507,GO:0009509,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009575,GO:0009579,GO:0009611,GO:0009628,GO:0009642,GO:0009644,GO:0009765,GO:0009941,GO:0009987,GO:0010206,GO:0010207,GO:0015979,GO:0016020,GO:0016043,GO:0019538,GO:0019684,GO:0019898,GO:0022607,GO:0030091,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0034622,GO:0035448,GO:0042170,GO:0042651,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0055035,GO:0065003,GO:0071704,GO:0071840,GO:1901564 - 0.00005156 53.0
TH2_k127_5017746_0 Aconitase C-terminal domain K01681 - 4.2.1.3 1.177e-209 660.0
TH2_k127_5017746_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 549.0
TH2_k127_5017746_2 Filamentation induced by cAMP protein fic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 522.0
TH2_k127_5017746_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 443.0
TH2_k127_5017746_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 335.0
TH2_k127_5017746_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000008464 78.0
TH2_k127_5029339_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 488.0
TH2_k127_5029339_1 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 446.0
TH2_k127_5029339_10 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 265.0
TH2_k127_5029339_11 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000001312 241.0
TH2_k127_5029339_12 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008305 233.0
TH2_k127_5029339_13 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000000126 228.0
TH2_k127_5029339_14 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000007909 221.0
TH2_k127_5029339_15 Polypeptide deformylase K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000003156 209.0
TH2_k127_5029339_16 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000001468 196.0
TH2_k127_5029339_17 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000003805 202.0
TH2_k127_5029339_18 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000181 183.0
TH2_k127_5029339_19 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000003567 132.0
TH2_k127_5029339_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 322.0
TH2_k127_5029339_20 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000005165 131.0
TH2_k127_5029339_21 OstA-like protein K09774 - - 0.0000000000000000000000000000003277 128.0
TH2_k127_5029339_22 Stringent starvation protein B K09985 - - 0.000000000000000000000000000001389 125.0
TH2_k127_5029339_23 PFAM EamA-like transporter family - - - 0.000000000000000000000000000306 124.0
TH2_k127_5029339_24 - - - - 0.0000000000000003413 81.0
TH2_k127_5029339_25 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000001284 86.0
TH2_k127_5029339_26 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.00005163 52.0
TH2_k127_5029339_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 318.0
TH2_k127_5029339_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 316.0
TH2_k127_5029339_5 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 316.0
TH2_k127_5029339_6 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 302.0
TH2_k127_5029339_7 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 291.0
TH2_k127_5029339_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008316 277.0
TH2_k127_5029339_9 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008965 270.0
TH2_k127_520566_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 363.0
TH2_k127_520566_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 331.0
TH2_k127_5209329_0 PFAM PHP domain protein K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000508 181.0
TH2_k127_5209329_1 KOW (Kyprides, Ouzounis, Woese) motif. K05785 - - 0.00000000000000000000000000000002607 131.0
TH2_k127_5209329_2 DNA-binding transcription factor activity K18996 - - 0.0000000000000000000000000004437 115.0
TH2_k127_5209329_3 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000001425 89.0
TH2_k127_5209329_4 Lipid A core-O-antigen ligase-like enyme K18814 - - 0.000000003088 64.0
TH2_k127_5244142_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 611.0
TH2_k127_5244142_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 550.0
TH2_k127_5244142_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 422.0
TH2_k127_5244142_3 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 334.0
TH2_k127_5244142_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 321.0
TH2_k127_5244142_5 nucleotide catabolic process - - - 0.000000000000000000000000000000000000000000000000006378 186.0
TH2_k127_5244142_6 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000005611 111.0
TH2_k127_5244142_7 Psort location Cytoplasmic, score K03655 - 3.6.4.12 0.0009065 44.0
TH2_k127_5277025_0 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 482.0
TH2_k127_5277025_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 427.0
TH2_k127_5277025_2 ATPase BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 363.0
TH2_k127_5277025_3 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000000000000000000004248 208.0
TH2_k127_5277025_4 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000003544 143.0
TH2_k127_527879_0 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 414.0
TH2_k127_527879_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 348.0
TH2_k127_527879_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007698 255.0
TH2_k127_527879_3 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000001139 242.0
TH2_k127_5309689_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 367.0
TH2_k127_5309689_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008037 295.0
TH2_k127_5309689_2 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000001261 198.0
TH2_k127_5309689_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000002703 132.0
TH2_k127_5309689_4 Preprotein translocase SecG subunit K03075 - - 0.000000000000000007363 87.0
TH2_k127_5309689_5 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.0000000000001459 74.0
TH2_k127_5309689_6 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.0000000533 54.0
TH2_k127_5315562_0 Belongs to the OprB family K07267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008292 274.0
TH2_k127_5315562_1 YMGG-like Gly-zipper - - - 0.000000000000000000000000000000000002182 142.0
TH2_k127_5315562_2 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000000000003419 141.0
TH2_k127_5315562_3 - - - - 0.000000001939 64.0
TH2_k127_540772_0 ABC transporter K15738 - - 4.855e-229 725.0
TH2_k127_540772_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 597.0
TH2_k127_540772_2 negative regulation of glucose mediated signaling pathway K01120 GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0006139,GO:0006163,GO:0006195,GO:0006198,GO:0006469,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009187,GO:0009214,GO:0009259,GO:0009261,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010563,GO:0010605,GO:0010646,GO:0010648,GO:0016787,GO:0016788,GO:0018130,GO:0019220,GO:0019222,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0023051,GO:0023057,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042325,GO:0042326,GO:0042578,GO:0043086,GO:0043549,GO:0043949,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0045859,GO:0045936,GO:0046058,GO:0046068,GO:0046069,GO:0046434,GO:0046483,GO:0046700,GO:0047555,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0055086,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071900,GO:0071901,GO:0072521,GO:0072523,GO:0080090,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1902531,GO:1902659,GO:1902660,GO:2000479,GO:2000480 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 304.0
TH2_k127_540772_3 response to abiotic stimulus K06867 GO:0008150,GO:0009314,GO:0009628,GO:0050896 - 0.00000000000000000000000000000000000000000000000000000000000000000000000005702 256.0
TH2_k127_540772_4 UDP-N-acetylmuramyl pentapeptide K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000001784 248.0
TH2_k127_540772_5 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000000000000000000000136 195.0
TH2_k127_540772_6 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000003123 183.0
TH2_k127_540772_7 Cold shock K03704 - - 0.00000000000000000000000001678 109.0
TH2_k127_5634572_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 484.0
TH2_k127_5634572_1 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000006021 158.0
TH2_k127_5634572_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000001383 76.0
TH2_k127_5641426_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1094.0
TH2_k127_5641426_1 Surface antigen K07277 - - 1.25e-248 788.0
TH2_k127_5641426_10 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 292.0
TH2_k127_5641426_11 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006695 276.0
TH2_k127_5641426_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000007388 244.0
TH2_k127_5641426_13 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000003366 213.0
TH2_k127_5641426_14 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003442 218.0
TH2_k127_5641426_15 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000002713 197.0
TH2_k127_5641426_16 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000001083 167.0
TH2_k127_5641426_17 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000003262 150.0
TH2_k127_5641426_18 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000258 131.0
TH2_k127_5641426_19 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000002984 111.0
TH2_k127_5641426_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 3.482e-224 698.0
TH2_k127_5641426_20 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001328 106.0
TH2_k127_5641426_21 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000003331 93.0
TH2_k127_5641426_22 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000001965 85.0
TH2_k127_5641426_23 Ribbon-helix-helix protein, copG family - - - 0.0000000000001398 74.0
TH2_k127_5641426_3 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 607.0
TH2_k127_5641426_4 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 595.0
TH2_k127_5641426_5 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 550.0
TH2_k127_5641426_6 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 549.0
TH2_k127_5641426_7 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 381.0
TH2_k127_5641426_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 376.0
TH2_k127_5641426_9 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 364.0
TH2_k127_5676408_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 513.0
TH2_k127_5676408_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 406.0
TH2_k127_5676408_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000008576 210.0
TH2_k127_5676408_3 Glycosyl transferase family 2 K09931 - - 0.00000000000000000000000000000000000000000000000000000002932 205.0
TH2_k127_5676408_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000459 149.0
TH2_k127_5676408_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000001165 139.0
TH2_k127_5676408_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000157 111.0
TH2_k127_5695466_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 5.329e-220 689.0
TH2_k127_5695466_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 481.0
TH2_k127_5695466_2 ABC transporter K01996 - - 0.000000000000000000000000000000000000605 140.0
TH2_k127_5695466_3 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000452 109.0
TH2_k127_5695466_4 PFAM Major Facilitator Superfamily - - - 0.0000000000000001253 81.0
TH2_k127_5695466_5 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000007322 73.0
TH2_k127_5695466_6 nuclease activity - - - 0.000000001519 62.0
TH2_k127_5808914_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1581.0
TH2_k127_5808914_1 NADH ubiquinone oxidoreductase K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 4.82e-200 639.0
TH2_k127_5808914_10 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 304.0
TH2_k127_5808914_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000039 287.0
TH2_k127_5808914_12 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005859 273.0
TH2_k127_5808914_13 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000136 269.0
TH2_k127_5808914_14 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000001018 241.0
TH2_k127_5808914_15 PFAM peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001445 242.0
TH2_k127_5808914_16 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000001755 216.0
TH2_k127_5808914_17 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000002069 175.0
TH2_k127_5808914_18 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000002422 161.0
TH2_k127_5808914_19 - - - - 0.00000000000000000000000000000000002125 145.0
TH2_k127_5808914_2 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 581.0
TH2_k127_5808914_20 PHP-associated - - - 0.0000000000000000000000000000000004542 138.0
TH2_k127_5808914_21 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000000003221 128.0
TH2_k127_5808914_22 cyclic nucleotide-binding - - - 0.000000000000000000000000000003703 124.0
TH2_k127_5808914_23 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000001527 117.0
TH2_k127_5808914_24 heat shock protein binding - - - 0.000000000000000001661 100.0
TH2_k127_5808914_25 transcription factor binding K02584 - - 0.00000001285 59.0
TH2_k127_5808914_26 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.000000151 52.0
TH2_k127_5808914_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 577.0
TH2_k127_5808914_4 Ammonium Transporter K03320 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 554.0
TH2_k127_5808914_5 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 510.0
TH2_k127_5808914_6 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 484.0
TH2_k127_5808914_7 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 462.0
TH2_k127_5808914_8 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 395.0
TH2_k127_5808914_9 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 361.0
TH2_k127_5827355_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 520.0
TH2_k127_5827355_1 PFAM multicopper oxidase type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 461.0
TH2_k127_5827355_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 431.0
TH2_k127_5827355_3 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 366.0
TH2_k127_5827355_4 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 353.0
TH2_k127_5827355_5 HlyD family K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 304.0
TH2_k127_5827355_6 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000849 276.0
TH2_k127_5827355_7 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000697 275.0
TH2_k127_5827355_8 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000006593 239.0
TH2_k127_5827355_9 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000001359 225.0
TH2_k127_5867447_0 chelatase, subunit ChlI K07391 - - 5.853e-198 627.0
TH2_k127_5867447_1 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 439.0
TH2_k127_5867447_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000002454 226.0
TH2_k127_5867447_3 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.000000000000000000000000000001411 124.0
TH2_k127_5867447_4 PAS domain K10125 - 2.7.13.3 0.00000000000000001272 99.0
TH2_k127_5871504_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.8e-216 682.0
TH2_k127_5871504_1 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000162 272.0
TH2_k127_5871504_2 - - - - 0.00000000000000000000000004683 110.0
TH2_k127_5872239_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 5.058e-282 890.0
TH2_k127_5872239_1 Glycosyl hydrolase family 57 - - - 1.025e-238 759.0
TH2_k127_5872239_10 - - - - 0.0000000000000000000002231 111.0
TH2_k127_5872239_11 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000001192 95.0
TH2_k127_5872239_12 Pfam SNARE associated Golgi protein - - - 0.00000000000145 69.0
TH2_k127_5872239_13 cell cycle K05589,K12065,K13052 - - 0.000000009164 60.0
TH2_k127_5872239_2 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 595.0
TH2_k127_5872239_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 472.0
TH2_k127_5872239_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 413.0
TH2_k127_5872239_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 386.0
TH2_k127_5872239_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000147 174.0
TH2_k127_5872239_7 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000002696 158.0
TH2_k127_5872239_8 - - - - 0.0000000000000000000000000000000000002366 143.0
TH2_k127_5872239_9 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000000001016 124.0
TH2_k127_5880711_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 623.0
TH2_k127_5880711_1 Histidine kinase - - - 0.00001434 48.0
TH2_k127_5903219_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 418.0
TH2_k127_5903219_1 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 328.0
TH2_k127_5903219_3 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.000000000000004601 78.0
TH2_k127_590399_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 4.358e-298 926.0
TH2_k127_590399_1 CO-methylating acetyl-CoA synthase activity K00193,K14138 - 2.3.1.169 2.201e-266 839.0
TH2_k127_590399_2 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.0000000000000596 72.0
TH2_k127_5976015_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 554.0
TH2_k127_5976015_1 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 326.0
TH2_k127_5976015_10 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000005027 108.0
TH2_k127_5976015_11 Patatin-like phospholipase K07001 - - 0.0000000000000000000005813 99.0
TH2_k127_5976015_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000002849 91.0
TH2_k127_5976015_13 sulfur carrier activity - - - 0.000000004361 60.0
TH2_k127_5976015_14 DsrE/DsrF-like family K07235 - - 0.000000006512 61.0
TH2_k127_5976015_15 energy transducer activity K03832 - - 0.0000001726 62.0
TH2_k127_5976015_16 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.0002746 48.0
TH2_k127_5976015_2 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 335.0
TH2_k127_5976015_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 314.0
TH2_k127_5976015_4 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000003332 232.0
TH2_k127_5976015_5 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000001892 201.0
TH2_k127_5976015_6 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000001118 199.0
TH2_k127_5976015_7 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000008114 189.0
TH2_k127_5976015_8 - - - - 0.0000000000000000000000000000000000000000000004021 175.0
TH2_k127_5976015_9 4Fe-4S dicluster domain - - - 0.0000000000000000000000000007045 113.0
TH2_k127_6063517_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 7.733e-195 621.0
TH2_k127_6063517_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000005903 192.0
TH2_k127_6070724_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.886e-279 882.0
TH2_k127_6070724_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.181e-264 841.0
TH2_k127_6070724_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000001456 96.0
TH2_k127_6070724_11 Protein of unknown function (DUF2400) - - - 0.000000000000003342 76.0
TH2_k127_6070724_12 Protein of unknown function (DUF721) - - - 0.00000001109 63.0
TH2_k127_6070724_13 Domain of unknown function (DUF4912) K09942 - - 0.000007929 58.0
TH2_k127_6070724_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 575.0
TH2_k127_6070724_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 329.0
TH2_k127_6070724_4 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 306.0
TH2_k127_6070724_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006961 276.0
TH2_k127_6070724_6 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000003236 260.0
TH2_k127_6070724_7 tRNA pseudouridylate synthase B C-terminal domain K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000002315 242.0
TH2_k127_6070724_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000006297 138.0
TH2_k127_6070724_9 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000008002 93.0
TH2_k127_6076919_0 TRCF K03723 - - 1.974e-234 762.0
TH2_k127_6076919_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 558.0
TH2_k127_6076919_10 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000002867 182.0
TH2_k127_6076919_11 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000000007685 150.0
TH2_k127_6076919_12 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000001723 138.0
TH2_k127_6076919_13 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000009059 136.0
TH2_k127_6076919_14 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.000000000000000000000000000000001997 143.0
TH2_k127_6076919_15 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000008753 126.0
TH2_k127_6076919_16 Cell surface protein - - - 0.00000000000000002995 96.0
TH2_k127_6076919_17 - - - - 0.000000000004475 73.0
TH2_k127_6076919_18 PIN domain - - - 0.00000000001548 65.0
TH2_k127_6076919_19 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.00000001187 58.0
TH2_k127_6076919_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 434.0
TH2_k127_6076919_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 416.0
TH2_k127_6076919_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 368.0
TH2_k127_6076919_5 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 363.0
TH2_k127_6076919_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002952 271.0
TH2_k127_6076919_7 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000559 238.0
TH2_k127_6076919_8 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000007885 223.0
TH2_k127_6076919_9 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000000966 201.0
TH2_k127_6150981_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 5.688e-252 796.0
TH2_k127_6150981_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.236e-232 734.0
TH2_k127_6150981_10 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000001505 226.0
TH2_k127_6150981_11 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000001231 219.0
TH2_k127_6150981_12 - - - - 0.0000000000000000000000000000000000000000000000000000000006579 208.0
TH2_k127_6150981_13 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000001332 194.0
TH2_k127_6150981_14 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000000000000000000000000000219 171.0
TH2_k127_6150981_15 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000006406 151.0
TH2_k127_6150981_16 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000004556 142.0
TH2_k127_6150981_17 Glu-tRNAGln amidotransferase C subunit K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000002049 116.0
TH2_k127_6150981_18 nucleotidyltransferase activity K07075 - - 0.000000000000000000000000003464 123.0
TH2_k127_6150981_19 Protein of unknown function (DUF3617) - - - 0.0000000000000000000004346 102.0
TH2_k127_6150981_2 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 538.0
TH2_k127_6150981_20 Domain of unknown function (DUF1858) - - - 0.00000000000000007291 82.0
TH2_k127_6150981_21 PFAM SirA family protein - - - 0.00000000008752 65.0
TH2_k127_6150981_22 4Fe-4S binding domain - - - 0.00000377 49.0
TH2_k127_6150981_23 Sulfurtransferase TusA - - - 0.000004207 49.0
TH2_k127_6150981_3 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 522.0
TH2_k127_6150981_4 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 473.0
TH2_k127_6150981_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 454.0
TH2_k127_6150981_6 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 353.0
TH2_k127_6150981_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 312.0
TH2_k127_6150981_8 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000009985 259.0
TH2_k127_6150981_9 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000003164 223.0
TH2_k127_6158007_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.908e-239 750.0
TH2_k127_6158007_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 430.0
TH2_k127_6158007_10 SpoVT / AbrB like domain - - - 0.00000000000000002702 84.0
TH2_k127_6158007_11 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000001803 62.0
TH2_k127_6158007_12 protein N-acetylglucosaminyltransferase activity - GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 - 0.000025 57.0
TH2_k127_6158007_2 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 369.0
TH2_k127_6158007_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000421 286.0
TH2_k127_6158007_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002052 275.0
TH2_k127_6158007_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000007205 182.0
TH2_k127_6158007_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000006714 170.0
TH2_k127_6158007_7 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.00000000000000000000000000000000000000000009113 166.0
TH2_k127_6158007_8 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000001018 159.0
TH2_k127_6158007_9 PIN domain - - - 0.00000000000000000000000000000000000001143 148.0
TH2_k127_6323030_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 603.0
TH2_k127_6323030_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005131 357.0
TH2_k127_6323030_10 PBP superfamily domain K02040 - - 0.000000000000000000000000000225 119.0
TH2_k127_6323030_11 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000001328 106.0
TH2_k127_6323030_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 312.0
TH2_k127_6323030_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 305.0
TH2_k127_6323030_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 309.0
TH2_k127_6323030_5 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009034 287.0
TH2_k127_6323030_6 HEAT repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005048 288.0
TH2_k127_6323030_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000001087 258.0
TH2_k127_6323030_8 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000001665 162.0
TH2_k127_6323030_9 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000008729 123.0
TH2_k127_6481525_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 538.0
TH2_k127_6481525_1 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004269 277.0
TH2_k127_6481525_2 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009453 250.0
TH2_k127_6481525_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000000000000000000001544 221.0
TH2_k127_6481525_4 response to heat K06149,K07090 - - 0.000000000000000000000000000000006039 144.0
TH2_k127_6481525_5 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000003905 121.0
TH2_k127_6546570_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 2.34e-233 738.0
TH2_k127_6546570_1 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000001272 166.0
TH2_k127_6546570_2 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000002891 109.0
TH2_k127_6630982_0 epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 559.0
TH2_k127_6630982_1 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 533.0
TH2_k127_6630982_2 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 343.0
TH2_k127_6630982_3 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000004856 145.0
TH2_k127_6675284_0 ABC transporter K06020 - 3.6.3.25 2.279e-309 956.0
TH2_k127_6675284_1 Protein of unknown function, DUF255 K06888 - - 3.499e-243 765.0
TH2_k127_6675284_10 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000000001674 173.0
TH2_k127_6675284_11 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000004544 168.0
TH2_k127_6675284_12 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000001086 173.0
TH2_k127_6675284_13 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000009001 123.0
TH2_k127_6675284_15 calcium, potassium:sodium antiporter activity K07301 - - 0.000000000000000000000001602 108.0
TH2_k127_6675284_16 PFAM Phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.00000000000000000000006724 103.0
TH2_k127_6675284_17 - - - - 0.0000000000000000001024 92.0
TH2_k127_6675284_18 Universal stress protein - - - 0.00000000000959 67.0
TH2_k127_6675284_19 PFAM Sodium calcium exchanger membrane region K07301 - - 0.000007049 49.0
TH2_k127_6675284_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 6.696e-201 632.0
TH2_k127_6675284_3 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 524.0
TH2_k127_6675284_4 GHKL domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 514.0
TH2_k127_6675284_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 451.0
TH2_k127_6675284_6 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 411.0
TH2_k127_6675284_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000131 287.0
TH2_k127_6675284_8 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006119 265.0
TH2_k127_6675284_9 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000001712 207.0
TH2_k127_6751201_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 570.0
TH2_k127_6751201_1 Chromate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 339.0
TH2_k127_6751201_2 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000006121 222.0
TH2_k127_6751201_3 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000002945 164.0
TH2_k127_6751201_4 Y_Y_Y domain - - - 0.000000005406 57.0
TH2_k127_6771660_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 584.0
TH2_k127_6771660_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 321.0
TH2_k127_6771660_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000002124 127.0
TH2_k127_6771660_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000002486 69.0
TH2_k127_6782323_0 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 381.0
TH2_k127_6782323_1 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 294.0
TH2_k127_6782323_2 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002491 289.0
TH2_k127_6782323_3 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.000000000000000000000000000000000000000004691 158.0
TH2_k127_6782323_4 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.000000000001024 81.0
TH2_k127_68104_0 Dehydratase family K01687 - 4.2.1.9 2.19e-260 811.0
TH2_k127_68104_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 3.174e-241 752.0
TH2_k127_68104_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 528.0
TH2_k127_68104_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 446.0
TH2_k127_68104_4 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 403.0
TH2_k127_68104_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000001219 241.0
TH2_k127_68104_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001967 246.0
TH2_k127_68104_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000001366 210.0
TH2_k127_68104_8 Protein of unknown function (DUF465) K09794 - - 0.0000000000000007312 79.0
TH2_k127_6833346_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 534.0
TH2_k127_6833346_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 518.0
TH2_k127_6833346_2 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 397.0
TH2_k127_6833346_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 332.0
TH2_k127_6833346_4 YbbR-like protein - - - 0.000000000000000000000000000000000000000004513 162.0
TH2_k127_6845190_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 330.0
TH2_k127_6845190_1 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 307.0
TH2_k127_6845190_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000001222 274.0
TH2_k127_6845190_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000002212 175.0
TH2_k127_6845190_4 energy transducer activity K03832 - - 0.00000000000000000000000000000000000000003768 163.0
TH2_k127_6845190_5 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000005267 161.0
TH2_k127_6845190_6 Universal stress protein family - - - 0.0000000000000000000000000000000000001856 147.0
TH2_k127_6845190_7 alpha beta - - - 0.000000000000000000000000000000000002815 149.0
TH2_k127_6845190_8 proteolysis K03665 - - 0.00000000000000000000000001158 116.0
TH2_k127_6845190_9 cytochrome complex assembly - - - 0.0000000000000000000000001047 107.0
TH2_k127_6849039_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1087.0
TH2_k127_6849039_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 431.0
TH2_k127_6849039_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000001453 106.0
TH2_k127_6849039_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 423.0
TH2_k127_6849039_3 COG3385 FOG Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 402.0
TH2_k127_6849039_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 397.0
TH2_k127_6849039_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 341.0
TH2_k127_6849039_6 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000711 156.0
TH2_k127_6849039_7 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000001539 151.0
TH2_k127_6849039_8 Thioredoxin-like - - - 0.00000000000000000000000000000000191 135.0
TH2_k127_6849039_9 PFAM Transposase K07491 - - 0.00000000000000000000000002487 111.0
TH2_k127_688649_0 PFAM DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002008 269.0
TH2_k127_688649_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000001402 153.0
TH2_k127_688649_2 Universal stress protein family - - - 0.0000000000001343 81.0
TH2_k127_688649_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000005694 61.0
TH2_k127_688649_5 SMART GGDEF domain containing protein - - - 0.000005312 50.0
TH2_k127_6894599_0 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1633.0
TH2_k127_6894599_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 325.0
TH2_k127_6894599_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006178 259.0
TH2_k127_6894599_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000001273 220.0
TH2_k127_6894599_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000001556 191.0
TH2_k127_6894599_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000462 146.0
TH2_k127_6894599_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000001496 74.0
TH2_k127_6894599_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000001667 73.0
TH2_k127_6894599_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000006027 73.0
TH2_k127_7018460_0 Sigma-54 interaction domain K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 407.0
TH2_k127_7018460_1 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 387.0
TH2_k127_7018460_10 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000001235 218.0
TH2_k127_7018460_11 cobalamin synthesis protein, P47K - - - 0.00000000000000000000000000000000000000000001451 173.0
TH2_k127_7018460_12 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000008399 143.0
TH2_k127_7018460_13 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000000000000000101 145.0
TH2_k127_7018460_14 PFAM Rubrerythrin - - - 0.000000000006691 65.0
TH2_k127_7018460_15 Peptidase family M48 - - - 0.00000000167 69.0
TH2_k127_7018460_2 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 339.0
TH2_k127_7018460_3 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009804 292.0
TH2_k127_7018460_4 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 302.0
TH2_k127_7018460_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001833 300.0
TH2_k127_7018460_6 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003459 262.0
TH2_k127_7018460_7 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000002258 253.0
TH2_k127_7018460_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000631 256.0
TH2_k127_7018460_9 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000001484 224.0
TH2_k127_7045953_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 538.0
TH2_k127_7045953_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 520.0
TH2_k127_7045953_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 494.0
TH2_k127_7045953_3 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001638 272.0
TH2_k127_7045953_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000001066 207.0
TH2_k127_7045953_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000005765 201.0
TH2_k127_7045953_6 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000001554 143.0
TH2_k127_7045953_7 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000005171 89.0
TH2_k127_7045953_9 Transcriptional regulators - - - 0.00001221 48.0
TH2_k127_7074073_0 COG0058 Glucan phosphorylase - - - 9.342e-248 774.0
TH2_k127_7173731_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 552.0
TH2_k127_7173731_1 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 444.0
TH2_k127_7173731_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000001093 90.0
TH2_k127_7173731_11 Polymer-forming cytoskeletal - - - 0.000000000000000001937 89.0
TH2_k127_7173731_12 Fimbrial assembly protein (PilN) K02461 - - 0.000000000002723 79.0
TH2_k127_7173731_2 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 359.0
TH2_k127_7173731_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 329.0
TH2_k127_7173731_4 Bacterial type II and III secretion system protein K02453,K03219 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 336.0
TH2_k127_7173731_5 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 315.0
TH2_k127_7173731_6 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 303.0
TH2_k127_7173731_7 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 297.0
TH2_k127_7173731_8 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003534 275.0
TH2_k127_7173731_9 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000001879 129.0
TH2_k127_7203252_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 473.0
TH2_k127_7203252_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 331.0
TH2_k127_7203252_2 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003031 280.0
TH2_k127_7203252_3 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004153 278.0
TH2_k127_7203252_4 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000219 246.0
TH2_k127_7203252_5 overlaps another CDS with the same product name - - - 0.00004129 48.0
TH2_k127_7238478_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 448.0
TH2_k127_7238478_1 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 394.0
TH2_k127_7238478_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001894 274.0
TH2_k127_7238478_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000002032 199.0
TH2_k127_7238478_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.0000000000000000000000000000000000000002211 155.0
TH2_k127_7238478_5 Protein of unknown function (DUF1016) - - - 0.000000000000000000000000000000000001239 143.0
TH2_k127_7238478_6 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0002533 49.0
TH2_k127_7261220_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 470.0
TH2_k127_7261220_1 Smr domain - - - 0.00000000000000000000000000000006648 127.0
TH2_k127_7290828_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.511e-199 639.0
TH2_k127_7290828_1 AsmA-like C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 481.0
TH2_k127_7290828_10 integral membrane protein - - - 0.00000004624 58.0
TH2_k127_7290828_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 394.0
TH2_k127_7290828_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 350.0
TH2_k127_7290828_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000006996 237.0
TH2_k127_7290828_5 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000000000000004355 141.0
TH2_k127_7290828_6 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000001318 139.0
TH2_k127_7290828_7 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.000000000000000000000000002579 113.0
TH2_k127_7307635_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 461.0
TH2_k127_7307635_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 301.0
TH2_k127_7307635_2 Alternative oxidase - - - 0.000000000000000000000000000000000001196 139.0
TH2_k127_7307635_3 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.0000000000000000000000000000001359 127.0
TH2_k127_7307635_4 - - - - 0.000000000002197 68.0
TH2_k127_739299_0 Polysaccharide biosynthesis/export protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 529.0
TH2_k127_739299_1 capsule polysaccharide export system inner membrane protein K10107 - - 0.000000000000000000000000000001275 125.0
TH2_k127_7419199_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 454.0
TH2_k127_7419199_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 297.0
TH2_k127_7419199_2 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003764 282.0
TH2_k127_7419199_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000003331 237.0
TH2_k127_7419199_4 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000003606 213.0
TH2_k127_7419199_5 protein conserved in bacteria K09928 - - 0.000000000000001101 82.0
TH2_k127_7420022_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 344.0
TH2_k127_7420022_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000005144 220.0
TH2_k127_7420022_2 PFAM PQ loop repeat K15383 - - 0.0000000000000000000000000001711 119.0
TH2_k127_7420022_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000003105 117.0
TH2_k127_7420022_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0008326 44.0
TH2_k127_7590319_0 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 302.0
TH2_k127_7590319_1 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008873 277.0
TH2_k127_7590319_2 phosphatidylglycerophosphatase activity K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.000000000000000000000000009095 117.0
TH2_k127_7590319_3 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000002331 115.0
TH2_k127_7590319_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000003579 66.0
TH2_k127_7666631_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 6.104e-278 866.0
TH2_k127_7666631_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 606.0
TH2_k127_7666631_10 Rhodanese Homology Domain - - - 0.0000000000000000000000000000002824 137.0
TH2_k127_7666631_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000001629 119.0
TH2_k127_7666631_12 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000004018 91.0
TH2_k127_7666631_13 Protein of unknown function (DUF520) K09767 - - 0.000000000000008515 75.0
TH2_k127_7666631_14 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000001063 71.0
TH2_k127_7666631_15 mercury ion transmembrane transporter activity K07213 - - 0.0000000000004592 72.0
TH2_k127_7666631_16 Universal stress protein - - - 0.000000648 58.0
TH2_k127_7666631_2 B3/4 domain K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 565.0
TH2_k127_7666631_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 480.0
TH2_k127_7666631_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 316.0
TH2_k127_7666631_5 Ami_2 K01447 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
TH2_k127_7666631_6 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000005911 216.0
TH2_k127_7666631_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000001395 194.0
TH2_k127_7666631_8 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000009361 186.0
TH2_k127_7666631_9 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000001202 144.0
TH2_k127_7712275_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 592.0
TH2_k127_7712275_1 MTH538 TIR-like domain (DUF1863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001836 253.0
TH2_k127_7712275_2 TPR Domain containing protein K12600 - - 0.00000000000000000000000000000000000000000000001156 187.0
TH2_k127_7712275_3 - - - - 0.0000000000000000000000000008521 121.0
TH2_k127_7712275_4 TM2 domain - - - 0.00000000000000000000000001611 114.0
TH2_k127_7712275_5 PFAM PASTA domain - - - 0.0000005025 62.0
TH2_k127_7712275_6 Tetratricopeptide repeats - - - 0.000009694 57.0
TH2_k127_7712275_7 TIR domain K08884,K12132 - 2.7.11.1 0.00007727 54.0
TH2_k127_7773903_0 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 354.0
TH2_k127_7773903_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005313 278.0
TH2_k127_7847405_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 6.562e-230 715.0
TH2_k127_7847405_1 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 528.0
TH2_k127_7847405_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 333.0
TH2_k127_7847405_3 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002265 248.0
TH2_k127_7847405_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000002232 211.0
TH2_k127_7847405_5 RDD family - - - 0.0000000000000000000000000007003 117.0
TH2_k127_7872436_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 403.0
TH2_k127_7872436_1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 311.0
TH2_k127_7872436_2 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000001397 150.0
TH2_k127_7872436_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000001494 153.0
TH2_k127_7872436_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000001968 129.0
TH2_k127_78851_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003085 285.0
TH2_k127_78851_1 Protein export membrane protein K07003 - - 0.000000000000000000000000000000000000000000000000003568 206.0
TH2_k127_78851_2 peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000002401 145.0
TH2_k127_78851_3 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000002326 92.0
TH2_k127_78851_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000368 93.0
TH2_k127_7885776_0 lipoprotein localization to outer membrane K02004,K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 387.0
TH2_k127_7885776_1 lipoprotein transporter activity K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 296.0
TH2_k127_7885776_2 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 288.0
TH2_k127_7885776_3 - - - - 0.0000000000000000000000000000000000000000000001377 172.0
TH2_k127_7912169_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 527.0
TH2_k127_7912169_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 503.0
TH2_k127_7912169_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 363.0
TH2_k127_7912169_3 CO dehydrogenase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 292.0
TH2_k127_7933566_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.408e-202 637.0
TH2_k127_7933566_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 482.0
TH2_k127_7933566_10 - - - - 0.000000000000000009299 84.0
TH2_k127_7933566_11 helicase activity - - - 0.00002662 48.0
TH2_k127_7933566_12 - - - - 0.00003734 55.0
TH2_k127_7933566_2 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 435.0
TH2_k127_7933566_3 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 340.0
TH2_k127_7933566_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000168 265.0
TH2_k127_7933566_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000005513 232.0
TH2_k127_7933566_6 - - - - 0.0000000000000000000000000000000000000000000000000005754 188.0
TH2_k127_7933566_7 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.000000000000000000000000000000000000000000000009614 181.0
TH2_k127_7933566_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000002425 157.0
TH2_k127_7933566_9 Protein of unknown function (DUF1189) - - - 0.00000000000000000000000000000000005025 144.0
TH2_k127_7943756_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000007219 209.0
TH2_k127_7943756_1 PFAM Acetyl-CoA hydrolase transferase K18122 - - 0.0000000000000000000000000000000007236 132.0
TH2_k127_7943756_2 membrane protein (DUF2207) - - - 0.00000000000000000000000000002962 124.0
TH2_k127_7969436_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 569.0
TH2_k127_7969436_1 CAAX prenyl protease N-terminal, five membrane helices - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 472.0
TH2_k127_7969436_10 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000001117 98.0
TH2_k127_7969436_11 Alternative oxidase - - - 0.0000000001683 65.0
TH2_k127_7969436_12 Carboxymuconolactone decarboxylase family - - - 0.0000000004214 66.0
TH2_k127_7969436_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 394.0
TH2_k127_7969436_3 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 323.0
TH2_k127_7969436_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 324.0
TH2_k127_7969436_5 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 310.0
TH2_k127_7969436_6 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004268 274.0
TH2_k127_7969436_7 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001271 273.0
TH2_k127_7969436_8 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000504 227.0
TH2_k127_7969436_9 HD domain - - - 0.000000000000000000000000000000000000000000000000009474 187.0
TH2_k127_8059992_0 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000003517 174.0
TH2_k127_8059992_1 Radical SAM domain protein - - - 0.000000000000000000000000000000000005278 143.0
TH2_k127_8059992_2 Domain of unknown function (DUF296) - - - 0.000000000005718 66.0
TH2_k127_8059992_3 Belongs to the peptidase S26 family - - - 0.0000000001268 70.0
TH2_k127_8143298_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.246e-228 716.0
TH2_k127_8143298_1 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000004312 267.0
TH2_k127_8143298_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000001108 109.0
TH2_k127_8143298_3 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.000000000000000000007822 96.0
TH2_k127_8143298_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000001771 49.0
TH2_k127_8205741_0 Domain of unknown function (DUF4139) - - - 1.689e-204 646.0
TH2_k127_8205741_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000195 208.0
TH2_k127_8205741_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000001224 188.0
TH2_k127_8205741_3 Histidine kinase - - - 0.00000000000000015 82.0
TH2_k127_8205741_4 Putative zinc-finger - - - 0.0000000000000008625 89.0
TH2_k127_8205741_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000006912 61.0
TH2_k127_8229871_0 Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid K00627,K05714,K10216,K10222,K10623 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0018771,GO:0019439,GO:0019622,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046164,GO:0046395,GO:0046435,GO:0052823,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 2.3.1.12,3.7.1.14,3.7.1.8,3.7.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 327.0
TH2_k127_8229871_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 336.0
TH2_k127_8246516_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 2.042e-214 673.0
TH2_k127_8246516_1 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 413.0
TH2_k127_8246516_10 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000004053 118.0
TH2_k127_8246516_11 Domain of unknown function (DUF370) K09777 - - 0.000000000000000000000000003896 113.0
TH2_k127_8246516_12 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000002581 106.0
TH2_k127_8246516_13 Tetratricopeptide repeat - - - 0.00000000000000000001521 104.0
TH2_k127_8246516_14 Psort location Cytoplasmic, score - - - 0.00000000000000000195 86.0
TH2_k127_8246516_15 Roadblock/LC7 domain - - - 0.000000000000000003496 89.0
TH2_k127_8246516_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 386.0
TH2_k127_8246516_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000002921 245.0
TH2_k127_8246516_4 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000006356 207.0
TH2_k127_8246516_5 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000134 195.0
TH2_k127_8246516_6 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000009032 183.0
TH2_k127_8246516_7 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000925 188.0
TH2_k127_8246516_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000003315 180.0
TH2_k127_8246516_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000003803 162.0
TH2_k127_8256729_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.259e-204 647.0
TH2_k127_8256729_1 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003181 265.0
TH2_k127_8256729_2 Phospholipid methyltransferase - - - 0.00000000000000000004897 98.0
TH2_k127_8267039_0 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000006424 214.0
TH2_k127_8267039_1 Two component signalling adaptor domain K03408 - - 0.0000000000000000003866 87.0
TH2_k127_8267039_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000002598 58.0
TH2_k127_8299946_0 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 460.0
TH2_k127_8299946_1 Fructose-1,6-bisphosphate aldolase, class II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000001127 157.0
TH2_k127_8299946_2 Aspartyl-tRNA amidotransferase K09117 - - 0.0000000000000000000000000000000000001605 147.0
TH2_k127_8299946_3 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000002031 83.0
TH2_k127_8309111_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 8.27e-198 627.0
TH2_k127_8309111_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 480.0
TH2_k127_8309111_2 Glycosyl transferase, family 2 K12992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 385.0
TH2_k127_8309111_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 324.0
TH2_k127_8309111_4 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004167 264.0
TH2_k127_8309111_5 SMART helix-turn-helix domain protein K15539 - - 0.0000000002934 70.0
TH2_k127_8309111_6 type II secretion system protein E K02454 - - 0.0000000008085 64.0
TH2_k127_8309111_7 heat shock protein binding K03686 - - 0.00000009018 65.0
TH2_k127_8355608_0 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 441.0
TH2_k127_8355608_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 415.0
TH2_k127_8355608_10 Branched-chain amino acid ABC transporter, ATP-binding protein K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002156 277.0
TH2_k127_8355608_11 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006002 295.0
TH2_k127_8355608_12 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001229 264.0
TH2_k127_8355608_13 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001831 242.0
TH2_k127_8355608_14 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002666 243.0
TH2_k127_8355608_15 response regulator K02485 - - 0.000000000000000000000000000000000000000000000000000104 189.0
TH2_k127_8355608_16 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000001874 190.0
TH2_k127_8355608_17 KR domain - - - 0.0000000000000000000000000000000000000000000000009068 184.0
TH2_k127_8355608_18 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000002431 113.0
TH2_k127_8355608_19 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.000000000000000000000000002862 119.0
TH2_k127_8355608_2 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 354.0
TH2_k127_8355608_20 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000007447 128.0
TH2_k127_8355608_21 Phosphopantetheine attachment site - - - 0.000000000000000002091 93.0
TH2_k127_8355608_22 integral membrane protein - - - 0.00000000000146 76.0
TH2_k127_8355608_23 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000004404 50.0
TH2_k127_8355608_24 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0001514 48.0
TH2_k127_8355608_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 346.0
TH2_k127_8355608_4 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 323.0
TH2_k127_8355608_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 325.0
TH2_k127_8355608_6 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 306.0
TH2_k127_8355608_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 302.0
TH2_k127_8355608_8 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008988 282.0
TH2_k127_8355608_9 ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008744 292.0
TH2_k127_8379844_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 564.0
TH2_k127_8379844_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 466.0
TH2_k127_8379844_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000004679 199.0
TH2_k127_8379844_3 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000005335 196.0
TH2_k127_8379844_4 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000002708 120.0
TH2_k127_8520_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1007.0
TH2_k127_8520_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 9.599e-300 927.0
TH2_k127_8520_10 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 330.0
TH2_k127_8520_11 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 316.0
TH2_k127_8520_12 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 304.0
TH2_k127_8520_13 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004168 285.0
TH2_k127_8520_14 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001636 283.0
TH2_k127_8520_15 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000001087 237.0
TH2_k127_8520_16 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000001437 218.0
TH2_k127_8520_17 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000894 174.0
TH2_k127_8520_18 His Kinase A (phosphoacceptor) domain K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000001116 170.0
TH2_k127_8520_19 - - - - 0.000000000000000000000000000000000003094 145.0
TH2_k127_8520_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 591.0
TH2_k127_8520_20 PFAM thiamineS protein - - - 0.000000000008229 68.0
TH2_k127_8520_21 - - - - 0.00000002047 56.0
TH2_k127_8520_23 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00008369 49.0
TH2_k127_8520_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 578.0
TH2_k127_8520_4 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 540.0
TH2_k127_8520_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 496.0
TH2_k127_8520_6 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 462.0
TH2_k127_8520_7 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 405.0
TH2_k127_8520_8 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 379.0
TH2_k127_8520_9 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 383.0
TH2_k127_8535998_0 metal ion transmembrane transporter activity K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 570.0
TH2_k127_8535998_1 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 566.0
TH2_k127_8535998_2 Glutamine amidotransferase class-I - - - 0.0000000003617 63.0
TH2_k127_8535998_3 electron transfer activity K05337,K17247 - - 0.0000001812 54.0
TH2_k127_8587258_0 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 430.0
TH2_k127_8587258_1 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 365.0
TH2_k127_8587258_2 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 332.0
TH2_k127_8587258_3 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 322.0
TH2_k127_8587258_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001283 283.0
TH2_k127_8587258_5 TIGRFAM iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000000000004285 182.0
TH2_k127_8587258_6 PFAM Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000000001696 152.0
TH2_k127_8587258_7 PFAM response regulator receiver - - - 0.000004299 53.0
TH2_k127_8659324_0 Tetratricopeptide repeat - - - 1.628e-195 642.0
TH2_k127_8659324_1 Domains REC, sigma54 interaction, HTH8 K02481 - - 7.886e-195 621.0
TH2_k127_8659324_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 507.0
TH2_k127_8659324_3 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 476.0
TH2_k127_8659324_4 Chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008209 286.0
TH2_k127_8659324_5 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000003219 246.0
TH2_k127_8659324_6 AAA domain K08252 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000003058 210.0
TH2_k127_8659324_7 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000004072 196.0
TH2_k127_8659324_8 Transcription termination factor nusG - - - 0.000000000000000000000000000000000000000000000000007045 185.0
TH2_k127_8659324_9 - - - - 0.000000000000000000000000000002683 123.0
TH2_k127_8707011_0 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 626.0
TH2_k127_8707011_1 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 594.0
TH2_k127_8707011_2 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 375.0
TH2_k127_87074_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 1.181e-295 930.0
TH2_k127_87074_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 597.0
TH2_k127_87074_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 454.0
TH2_k127_87074_3 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 344.0
TH2_k127_87074_4 NAD(P)H dehydrogenase K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000007869 230.0
TH2_k127_87074_5 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000001018 134.0
TH2_k127_87074_6 thiosulfate sulfurtransferase activity - - - 0.00000000004749 64.0
TH2_k127_8756180_0 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 392.0
TH2_k127_8756180_1 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 331.0
TH2_k127_8756180_2 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 307.0
TH2_k127_8756180_3 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001465 250.0
TH2_k127_8756180_4 - - - - 0.0000000000000000000000000000000000000000000000000007431 188.0
TH2_k127_8756180_5 Ion channel - - - 0.00000000000000000000000000000000003744 140.0
TH2_k127_8756180_6 - - - - 0.0000000000000000000000000000002417 127.0
TH2_k127_8855379_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 1.983e-254 796.0
TH2_k127_8855379_1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 400.0
TH2_k127_8855379_2 Chain length determinant protein K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 332.0
TH2_k127_8855379_3 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 286.0
TH2_k127_8855379_4 export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001226 283.0
TH2_k127_8855379_5 Putative beta-barrel porin 2 K20920 - - 0.000000000000000000000000000000000000000009011 175.0
TH2_k127_909963_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 398.0
TH2_k127_909963_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 327.0
TH2_k127_909963_10 Regulatory protein, FmdB family - - - 0.000000000000000002489 86.0
TH2_k127_909963_11 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000008265 89.0
TH2_k127_909963_12 - - - - 0.000000000001773 76.0
TH2_k127_909963_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 297.0
TH2_k127_909963_3 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 280.0
TH2_k127_909963_4 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003346 222.0
TH2_k127_909963_5 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000005154 205.0
TH2_k127_909963_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000002089 207.0
TH2_k127_909963_7 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000000004908 172.0
TH2_k127_909963_9 - - - - 0.000000000000000002475 92.0
TH2_k127_933956_0 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 400.0
TH2_k127_933956_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001101 274.0
TH2_k127_933956_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000006544 178.0
TH2_k127_933956_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000001083 134.0
TH2_k127_998863_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.459e-237 745.0
TH2_k127_998863_1 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 422.0
TH2_k127_998863_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 408.0
TH2_k127_998863_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005533 263.0
TH2_k127_998863_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000004241 226.0
TH2_k127_998863_5 Dihydroorotate dehydrogenase electron transfer subunit K02823 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0042602,GO:0052875,GO:0055114 - 0.00000000000000000000000000000000000000000000000002853 188.0
TH2_k127_998863_6 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.000000000000000496 78.0
TH2_k127_998863_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000007974 59.0