Overview

ID MAG03902
Name TH2_bin.27
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Planctomycetota
Class Phycisphaerae
Order Sedimentisphaerales
Family Anaerohalosphaeraceae
Genus UBA7708
Species
Assembly information
Completeness (%) 71.4
Contamination (%) 0.88
GC content (%) 49.0
N50 (bp) 8,177
Genome size (bp) 1,890,676

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1606

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1074_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.96e-251 817.0
TH2_k127_1074_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 367.0
TH2_k127_1074_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000498 187.0
TH2_k127_1074_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000007184 135.0
TH2_k127_1074_4 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000001937 85.0
TH2_k127_117531_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 499.0
TH2_k127_117531_1 COG2211 Na melibiose symporter and related transporters K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 410.0
TH2_k127_1194107_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 293.0
TH2_k127_1194107_1 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005297 254.0
TH2_k127_1194107_3 Sigma-54 interaction domain - - - 0.00002083 47.0
TH2_k127_1196509_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 377.0
TH2_k127_1196509_1 PFAM PfkB - - - 0.00005332 45.0
TH2_k127_1196569_0 flagellar hook-associated protein K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000001161 258.0
TH2_k127_1196569_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - 0.0000000000000001254 92.0
TH2_k127_1196569_2 Rod binding protein K02395 - - 0.0005502 47.0
TH2_k127_1196796_0 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 612.0
TH2_k127_1196796_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006427 288.0
TH2_k127_1208374_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 432.0
TH2_k127_1208374_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 319.0
TH2_k127_1208374_2 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001309 296.0
TH2_k127_1208374_3 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000487 266.0
TH2_k127_1208374_4 Outer membrane protein assembly complex, YaeT protein K07277 - - 0.0000000000000000000000000000000000000000000000000000000000001314 224.0
TH2_k127_1208374_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000001562 222.0
TH2_k127_1208374_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000002702 198.0
TH2_k127_1208374_8 Transposase - - - 0.0000000000007957 69.0
TH2_k127_1208374_9 Outer membrane protein (OmpH-like) - - - 0.000000004924 65.0
TH2_k127_1230075_0 Tetratricopeptide repeat - - - 0.000007751 57.0
TH2_k127_1232969_0 Sulfatase K01130 - 3.1.6.1 0.0 1308.0
TH2_k127_1232969_1 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000114 142.0
TH2_k127_1232969_2 - - - - 0.000000000000000000000008652 106.0
TH2_k127_1232985_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 3.741e-298 947.0
TH2_k127_1232985_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001179 246.0
TH2_k127_1232985_2 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000003354 183.0
TH2_k127_1232985_3 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.00000000000000000000000000000214 128.0
TH2_k127_1232985_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.0000000000000000000000000001045 130.0
TH2_k127_1232985_5 Transcriptional regulator - - - 0.00000000000000000168 94.0
TH2_k127_1232985_7 MarC family integral membrane protein K05595 - - 0.00007066 46.0
TH2_k127_1244734_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 468.0
TH2_k127_1244734_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 359.0
TH2_k127_1244734_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 327.0
TH2_k127_1244734_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 306.0
TH2_k127_1244734_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001387 280.0
TH2_k127_1244734_5 COG COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000001365 243.0
TH2_k127_1244734_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000002777 221.0
TH2_k127_1244734_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000001038 108.0
TH2_k127_1244734_8 - - - - 0.0000000000000000000000126 106.0
TH2_k127_1244734_9 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000001712 57.0
TH2_k127_1248872_0 Anthranilate synthase component I, N terminal region K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 318.0
TH2_k127_1248872_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000002969 198.0
TH2_k127_126201_0 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 358.0
TH2_k127_126201_1 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004695 274.0
TH2_k127_126201_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005458 263.0
TH2_k127_126201_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000003589 207.0
TH2_k127_1279409_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001031 271.0
TH2_k127_1279409_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000001889 141.0
TH2_k127_1279409_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000004346 132.0
TH2_k127_1290001_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 391.0
TH2_k127_1290001_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 383.0
TH2_k127_1290001_2 PFAM GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000001302 249.0
TH2_k127_1290001_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000006926 223.0
TH2_k127_1290001_4 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000001335 128.0
TH2_k127_1300752_0 DRTGG domain K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009777 273.0
TH2_k127_1300752_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000003681 232.0
TH2_k127_1300752_2 - - - - 0.000000001469 70.0
TH2_k127_1312062_0 - - - - 0.00000000000000000000000000000000000000000000000008536 190.0
TH2_k127_1312062_1 Cold shock protein K03704 - - 0.0000000000000000000002164 97.0
TH2_k127_1312062_2 general secretion pathway protein K02456 - - 0.000000009136 66.0
TH2_k127_1312062_3 - - - - 0.000003332 56.0
TH2_k127_1323806_0 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 458.0
TH2_k127_1323806_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 399.0
TH2_k127_1323806_2 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 385.0
TH2_k127_1323806_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000004654 158.0
TH2_k127_1323806_4 Bacterial regulatory proteins, tetR family - - - 0.00000000001157 72.0
TH2_k127_1323806_5 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000001003 63.0
TH2_k127_133978_0 best DB hits BLAST gb AAD45539.1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 443.0
TH2_k127_133978_1 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 382.0
TH2_k127_133978_2 Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 322.0
TH2_k127_133978_3 - - - - 0.00000000172 60.0
TH2_k127_1354634_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 378.0
TH2_k127_1354634_1 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 332.0
TH2_k127_1354634_2 MFS/sugar transport protein K03292 - - 0.00000000000000000000000000000000000000000000000000000000000004601 232.0
TH2_k127_1354634_3 Periplasmic binding proteins and sugar binding domain of LacI family K02529 - - 0.000000000000000000000000000000000000000000000000000000000003512 223.0
TH2_k127_1354634_4 Belongs to the glycosyl hydrolase 2 family K01192,K15855 - 3.2.1.165,3.2.1.25 0.000000000000000000000000000000000000000000007063 174.0
TH2_k127_1354634_6 - - - - 0.000000000000000000000000000004048 139.0
TH2_k127_1354634_7 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000158 114.0
TH2_k127_1354634_8 Two component signalling adaptor domain K03408 - - 0.000000000000000000000002283 105.0
TH2_k127_1354634_9 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0002152 45.0
TH2_k127_1376948_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 558.0
TH2_k127_1376948_1 helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 552.0
TH2_k127_1376948_10 regulation of circadian rhythm K06919 - - 0.00000000000000000000000000004764 130.0
TH2_k127_1376948_11 - - - - 0.000000000000000000000008235 107.0
TH2_k127_1376948_12 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000009709 83.0
TH2_k127_1376948_13 Right handed beta helix region - - - 0.000000003583 63.0
TH2_k127_1376948_14 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.00000006922 59.0
TH2_k127_1376948_2 Protein of unknown function (DUF475) K09799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 422.0
TH2_k127_1376948_3 PFAM glycoside hydrolase, family 10 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005223 291.0
TH2_k127_1376948_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000004193 246.0
TH2_k127_1376948_5 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000004263 233.0
TH2_k127_1376948_6 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000004396 218.0
TH2_k127_1376948_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000003497 198.0
TH2_k127_1376948_8 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000009321 164.0
TH2_k127_1376948_9 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000008997 138.0
TH2_k127_140248_0 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 616.0
TH2_k127_140248_1 tagaturonate epimerase K21619 - 5.1.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 553.0
TH2_k127_140248_10 - - - - 0.0000000000000008464 78.0
TH2_k127_140248_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001915 260.0
TH2_k127_140248_3 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000001004 190.0
TH2_k127_140248_4 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000001212 179.0
TH2_k127_140248_5 - - - - 0.0000000000000000000000000000000000000000249 157.0
TH2_k127_140248_6 - - - - 0.00000000000000000000000000000000000002362 156.0
TH2_k127_140248_7 PFAM Conserved TM helix - - - 0.000000000000000000000000000000001584 138.0
TH2_k127_140248_8 ROK family - - - 0.000000000000000000000000000000005142 139.0
TH2_k127_140248_9 Protein of unknown function (DUF3185) - - - 0.0000000000000000004082 88.0
TH2_k127_1411241_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 452.0
TH2_k127_1411241_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000474 154.0
TH2_k127_1411241_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.0000000001038 65.0
TH2_k127_1411241_3 Protein of unknown function (DUF2752) - - - 0.000001397 56.0
TH2_k127_1437937_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 377.0
TH2_k127_1437937_1 PFAM type II and III secretion system protein K02666 - - 0.00000000000000001365 97.0
TH2_k127_1437937_2 Belongs to the GSP D family K02280 - - 0.0000000000001943 84.0
TH2_k127_1451534_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 337.0
TH2_k127_1451534_1 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000305 188.0
TH2_k127_1451572_0 Transposase domain (DUF772) K07481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 454.0
TH2_k127_1451572_1 Flagellar motor protein K02557 - - 0.0000000000000000000000000000000000000000001263 169.0
TH2_k127_1451572_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000003431 52.0
TH2_k127_1514774_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 3.834e-299 955.0
TH2_k127_1514774_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 8.854e-210 670.0
TH2_k127_1514774_10 - - - - 0.00000000000000000000000008645 113.0
TH2_k127_1514774_11 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07713 - - 0.0000000000000000001446 92.0
TH2_k127_1514774_12 Domain of unknown function (DUF3786) - - - 0.0000000000000000002561 95.0
TH2_k127_1514774_13 - - - - 0.0000000000000417 81.0
TH2_k127_1514774_14 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000008214 53.0
TH2_k127_1514774_2 PFAM ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 527.0
TH2_k127_1514774_3 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 387.0
TH2_k127_1514774_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 291.0
TH2_k127_1514774_5 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001752 304.0
TH2_k127_1514774_6 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000004557 215.0
TH2_k127_1514774_7 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000002359 157.0
TH2_k127_1514774_8 PadR family transcriptional regulator K10947 - - 0.00000000000000000000000000000000006365 136.0
TH2_k127_1514774_9 PFAM metal-dependent phosphohydrolase HD sub - - - 0.0000000000000000000000000005313 121.0
TH2_k127_1529643_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 620.0
TH2_k127_1529643_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 620.0
TH2_k127_1529643_2 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 475.0
TH2_k127_1529643_3 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 370.0
TH2_k127_1529643_4 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 286.0
TH2_k127_1529643_5 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000002035 133.0
TH2_k127_1529643_6 PFAM O-Antigen - - - 0.0000000000000000001394 104.0
TH2_k127_1529643_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000003377 67.0
TH2_k127_1529643_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000001874 68.0
TH2_k127_153851_0 with chaperone activity ATP-binding K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 533.0
TH2_k127_153851_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 451.0
TH2_k127_153851_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 301.0
TH2_k127_153851_3 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000003701 183.0
TH2_k127_153851_4 PFAM Thioesterase superfamily K02614 - - 0.000000000000000000000000000000000001496 142.0
TH2_k127_154137_0 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 491.0
TH2_k127_154137_1 PFAM Flagellar assembly protein FliH Type III secretion system HrpE K02411 - - 0.0000004516 59.0
TH2_k127_1632477_0 argininosuccinate synthase activity K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 490.0
TH2_k127_1632477_1 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000002934 231.0
TH2_k127_1632477_2 Bacterial regulatory protein, arsR - - - 0.000000000000000002567 87.0
TH2_k127_1678254_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000001372 110.0
TH2_k127_1678254_1 - - - - 0.0000000226 61.0
TH2_k127_1678254_2 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.000551 53.0
TH2_k127_1693876_0 KilA-N - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 396.0
TH2_k127_1693876_1 PFAM Radical SAM K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 346.0
TH2_k127_1693876_2 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000004928 234.0
TH2_k127_1693876_3 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000001929 228.0
TH2_k127_1693876_4 flagellar biosynthetic protein FliR K02421 - - 0.00000000000000002498 93.0
TH2_k127_1693876_5 Role in flagellar biosynthesis K02420 - - 0.0000000000000005864 80.0
TH2_k127_1693876_6 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0000000000006567 81.0
TH2_k127_1693876_7 flagellar K02418 - - 0.000002556 55.0
TH2_k127_1698398_0 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002194 287.0
TH2_k127_1698398_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000005622 202.0
TH2_k127_1698398_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000004291 202.0
TH2_k127_1698398_3 TPR Domain containing protein K12600 - - 0.000000000000000000000000005555 125.0
TH2_k127_1698398_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000004981 113.0
TH2_k127_17306_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 428.0
TH2_k127_17306_1 Redoxin - - - 0.0000000000000000000000000000000000000000007297 165.0
TH2_k127_17306_2 Type II secretion system K02653 - - 0.0005305 52.0
TH2_k127_1731899_0 Oxidoreductase family, C-terminal alpha beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 576.0
TH2_k127_1731899_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 521.0
TH2_k127_1731899_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 396.0
TH2_k127_1749356_0 general secretion pathway protein D K02453 - - 0.00000001378 69.0
TH2_k127_176823_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 556.0
TH2_k127_176823_1 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001272 247.0
TH2_k127_176823_2 PFAM Glycosyl transferase family 2 - - - 0.00000002919 59.0
TH2_k127_1782912_0 Belongs to the carbamoyltransferase HypF family K04656 - - 1.02e-196 638.0
TH2_k127_1782912_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 537.0
TH2_k127_1782912_10 PFAM Glucosamine-6-phosphate isomerases 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000002503 85.0
TH2_k127_1782912_11 Preprotein translocase subunit K03210 - - 0.00000000004906 69.0
TH2_k127_1782912_12 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000001351 63.0
TH2_k127_1782912_13 BON domain - - - 0.00000001796 60.0
TH2_k127_1782912_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 442.0
TH2_k127_1782912_3 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 364.0
TH2_k127_1782912_4 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 337.0
TH2_k127_1782912_5 rna polymerase alpha K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 307.0
TH2_k127_1782912_6 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000052 237.0
TH2_k127_1782912_7 Stage II sporulation D domain protein K06381 - - 0.000000000000000000000000000000000000002016 162.0
TH2_k127_1782912_8 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000001962 103.0
TH2_k127_1782912_9 hydrogenase assembly chaperone HypC HupF K04653 - - 0.0000000000000005364 80.0
TH2_k127_1785711_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.357e-223 707.0
TH2_k127_1785711_1 Trypsin K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000789 262.0
TH2_k127_1785711_2 Iron (Metal) dependent repressor, DtxR family K03709 - - 0.000000000000000000000000000002587 123.0
TH2_k127_182740_0 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000000000000002277 139.0
TH2_k127_182740_1 glycosyl transferase - - - 0.0000000000004275 83.0
TH2_k127_1933369_0 Belongs to the glycosyl hydrolase 2 family K01192,K15855 - 3.2.1.165,3.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 337.0
TH2_k127_1933369_1 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 307.0
TH2_k127_1933369_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 295.0
TH2_k127_199142_0 Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 417.0
TH2_k127_199142_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 402.0
TH2_k127_199142_2 Integral membrane protein (PIN domain superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 332.0
TH2_k127_199142_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000686 241.0
TH2_k127_199142_4 Histidine kinase - - - 0.0000000000000000000000000000000000003253 156.0
TH2_k127_199142_5 - - - - 0.00000000001283 68.0
TH2_k127_204915_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.411e-231 721.0
TH2_k127_204915_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 469.0
TH2_k127_204915_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 428.0
TH2_k127_204915_3 Nitrite and sulphite reductase 4Fe-4S K00392 - 1.8.7.1 0.000000000000000000000000000000001911 142.0
TH2_k127_204915_4 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.0000000000000000000375 93.0
TH2_k127_204915_5 Protein of unknown function (DUF3034) - - - 0.0000001625 62.0
TH2_k127_204915_6 DNA polymerase Ligase (LigD) - - - 0.0000003712 55.0
TH2_k127_204915_7 Uncharacterized small protein (DUF2292) - - - 0.00003167 49.0
TH2_k127_2054425_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 334.0
TH2_k127_2054425_1 Flagellar basal body-associated protein FliL - - - 0.0000000000000194 80.0
TH2_k127_2054425_2 Tetratricopeptide repeat protein - - - 0.0003395 53.0
TH2_k127_2251332_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 543.0
TH2_k127_2251332_1 FHA domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000005508 259.0
TH2_k127_2251332_2 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.000000000000000000000000000000000000004755 156.0
TH2_k127_2251332_3 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145 - 0.000000000000000000003297 96.0
TH2_k127_2251332_4 - - - - 0.00000008476 62.0
TH2_k127_227179_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000001843 211.0
TH2_k127_227179_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000004338 154.0
TH2_k127_227179_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000002845 83.0
TH2_k127_227179_3 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000002945 55.0
TH2_k127_2320362_0 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000484 285.0
TH2_k127_2320362_1 Sensory domain found in PocR - - - 0.00000000000000000000000000000000899 149.0
TH2_k127_2320362_2 NMT1/THI5 like - - - 0.000000000000000000000000002837 131.0
TH2_k127_2321169_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.752e-200 636.0
TH2_k127_2321169_1 SMART chemotaxis sensory transducer K03406,K13487 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 582.0
TH2_k127_2321169_2 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000008483 193.0
TH2_k127_2321169_3 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000005538 124.0
TH2_k127_2353813_0 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 440.0
TH2_k127_2353813_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 347.0
TH2_k127_2353813_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001744 278.0
TH2_k127_2353813_3 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000003557 237.0
TH2_k127_2353813_4 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000002626 216.0
TH2_k127_2353813_5 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000009012 153.0
TH2_k127_2353813_6 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000001717 141.0
TH2_k127_2353813_7 23S rRNA-intervening sequence protein - - - 0.00000000000000000000001388 105.0
TH2_k127_2361030_0 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 456.0
TH2_k127_2361030_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 344.0
TH2_k127_2361030_2 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 329.0
TH2_k127_2361030_3 TIGRFAM phosphate ABC transporter, inner membrane subunit PstC K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 306.0
TH2_k127_2361030_4 phosphate ion binding K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000006407 240.0
TH2_k127_2361030_5 Putative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000449 241.0
TH2_k127_2361030_6 PhoU domain K02039 - - 0.00000000000000000000000000000000000000000000000000000000000001884 221.0
TH2_k127_2361030_7 PFAM CHAD domain containing protein - - - 0.000000000000002086 83.0
TH2_k127_2361030_8 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000002415 73.0
TH2_k127_2361030_9 Sugar-binding cellulase-like - - - 0.00003999 49.0
TH2_k127_2362756_0 ABC-type multidrug transport system ATPase component K13926 - - 0.0 1472.0
TH2_k127_2362756_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1300.0
TH2_k127_2362756_10 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 407.0
TH2_k127_2362756_11 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000006282 254.0
TH2_k127_2362756_12 transcriptional regulator - GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000001738 219.0
TH2_k127_2362756_13 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000004541 178.0
TH2_k127_2362756_14 PTS system, Lactose/Cellobiose specific IIB subunit K02769 - 2.7.1.202 0.000000000000000000000000000000009087 129.0
TH2_k127_2362756_15 Domain of unknown function (DUF4136) - - - 0.0000006633 59.0
TH2_k127_2362756_16 Belongs to the Fur family K09825 - - 0.0005693 43.0
TH2_k127_2362756_2 Glycosyl hydrolase family 38 C-terminal domain protein K01191 - 3.2.1.24 0.0 1138.0
TH2_k127_2362756_3 Electron transfer flavoprotein, alpha subunit K03522 - - 1.029e-282 884.0
TH2_k127_2362756_4 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 8.159e-227 714.0
TH2_k127_2362756_5 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183,K11189,K11201 - 2.7.1.202,2.7.3.9 7.985e-207 670.0
TH2_k127_2362756_6 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 589.0
TH2_k127_2362756_7 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 574.0
TH2_k127_2362756_8 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100,K03444,K08138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 502.0
TH2_k127_2362756_9 TIGRFAM PTS system, fructose subfamily, IIC subunit K02768,K02769,K02770,K11203 - 2.7.1.202 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 437.0
TH2_k127_2393379_0 Heavy metal translocating P-type atpase K01534,K17686 - 3.6.3.3,3.6.3.5,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 551.0
TH2_k127_2393379_1 ABC-type multidrug transport system ATPase K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 305.0
TH2_k127_2393379_3 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000001704 248.0
TH2_k127_2393379_4 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000005135 164.0
TH2_k127_2393379_5 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.000000000000000000000000000000000000000001279 168.0
TH2_k127_2393379_6 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000001762 150.0
TH2_k127_2393379_7 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000002105 101.0
TH2_k127_2404611_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007955 288.0
TH2_k127_2404611_1 Sensory domain found in PocR K07720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002826 266.0
TH2_k127_2404611_2 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000004513 237.0
TH2_k127_2404611_3 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000191 201.0
TH2_k127_2404611_4 Rhomboid family - - - 0.0000000000000000000000000000000005137 141.0
TH2_k127_2404611_5 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000005479 109.0
TH2_k127_2404611_6 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000007611 51.0
TH2_k127_243096_0 TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 572.0
TH2_k127_243096_1 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 511.0
TH2_k127_243096_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 454.0
TH2_k127_243096_3 polygalacturonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000003386 246.0
TH2_k127_243096_4 MFS/sugar transport protein K03292 - - 0.0000000000000000000000000000000000000000000000000000000008023 226.0
TH2_k127_243096_5 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.000000000000000000000000000000000000007573 149.0
TH2_k127_243096_6 Protein of unknown function (DUF401) K09133 - - 0.000000000000000000000000000000000003813 154.0
TH2_k127_243096_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.0000000000000000002762 88.0
TH2_k127_243096_8 IS30 family K07482 - - 0.0000000000008448 68.0
TH2_k127_243096_9 - - - - 0.00000005854 55.0
TH2_k127_2444595_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 586.0
TH2_k127_2444595_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 341.0
TH2_k127_2444595_2 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000003442 167.0
TH2_k127_2449627_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000006521 238.0
TH2_k127_2449627_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000001706 167.0
TH2_k127_2449627_2 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000006412 168.0
TH2_k127_2470106_0 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 323.0
TH2_k127_2470106_1 RNA pseudouridylate synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 298.0
TH2_k127_2470106_2 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 304.0
TH2_k127_2470106_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000002571 240.0
TH2_k127_2470106_4 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.0000000000000000000000000000000000000000000001725 177.0
TH2_k127_2470106_5 binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription this protein is involved in detoxification and protection against antimicrobial K03088 - - 0.0000000000000000124 90.0
TH2_k127_2470106_6 Helix-turn-helix domain - - - 0.00000000000000002936 91.0
TH2_k127_2470106_7 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.0000000000007631 78.0
TH2_k127_2474736_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000002841 226.0
TH2_k127_2474736_1 GAF domain - - - 0.000000000000000000000000000000000000000000003176 178.0
TH2_k127_248886_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 477.0
TH2_k127_248886_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 378.0
TH2_k127_248886_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000002583 199.0
TH2_k127_248886_3 Binds directly to 16S ribosomal RNA K02968 - - 0.0002281 47.0
TH2_k127_248903_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 312.0
TH2_k127_248903_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 298.0
TH2_k127_248903_2 Anthranilate synthase K01658 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000002296 211.0
TH2_k127_248903_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000005584 185.0
TH2_k127_248903_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.000000000000000000000000001794 113.0
TH2_k127_2611120_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 4.733e-214 675.0
TH2_k127_2611120_1 Transcriptional regulator - - - 0.000000000000000000000000000000000006491 141.0
TH2_k127_2611120_2 sulfate reduction K00366,K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.7.7.1,1.8.4.10,1.8.4.8,2.7.1.25 0.0000000000000008029 79.0
TH2_k127_2611120_3 membrane K00860,K00956 - 2.7.1.25,2.7.7.4 0.000000000000004472 77.0
TH2_k127_2650806_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 505.0
TH2_k127_2650806_1 C-terminal region of band_7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 428.0
TH2_k127_2650806_10 VanZ like family - - - 0.00005682 53.0
TH2_k127_2650806_11 Tetratricopeptide repeat - - - 0.0001349 55.0
TH2_k127_2650806_12 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0002902 51.0
TH2_k127_2650806_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 339.0
TH2_k127_2650806_3 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 304.0
TH2_k127_2650806_4 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000002744 211.0
TH2_k127_2650806_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000001068 195.0
TH2_k127_2650806_6 response regulator receiver - - - 0.00000000000000000000000000000000000000000001516 168.0
TH2_k127_2650806_7 - - - - 0.000000000000000000000000000000000000197 153.0
TH2_k127_2650806_8 NfeD-like C-terminal, partner-binding - - - 0.00000000000000001793 89.0
TH2_k127_2650806_9 COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes - - - 0.000001099 55.0
TH2_k127_26958_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 603.0
TH2_k127_26958_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 366.0
TH2_k127_26958_2 Ppx GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 348.0
TH2_k127_26958_3 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 340.0
TH2_k127_26958_4 polygalacturonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 304.0
TH2_k127_26958_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003595 271.0
TH2_k127_26958_6 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000001871 131.0
TH2_k127_26958_7 PFAM CHAD domain containing protein - - - 0.0000000000000000000000006227 111.0
TH2_k127_26958_8 - - - - 0.000000001106 61.0
TH2_k127_2729018_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 558.0
TH2_k127_2729018_1 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000004008 213.0
TH2_k127_2729018_2 ACT domain - - - 0.000000000000000001136 88.0
TH2_k127_2862499_0 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000001919 81.0
TH2_k127_2862499_1 Polymer-forming cytoskeletal - - - 0.0000000003417 72.0
TH2_k127_2862499_2 Pilus assembly protein PilX - - - 0.000000001672 70.0
TH2_k127_28748_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 456.0
TH2_k127_28748_1 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 317.0
TH2_k127_28748_2 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006822 256.0
TH2_k127_28748_3 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000001995 188.0
TH2_k127_28748_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000002318 169.0
TH2_k127_28748_5 MarC family integral membrane protein K05595 - - 0.0000000000000000000000007971 111.0
TH2_k127_28748_6 CTP reductase activity K21636 - 1.1.98.6 0.00000006013 61.0
TH2_k127_329715_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 400.0
TH2_k127_329715_1 cobalamin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 329.0
TH2_k127_329715_2 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.0000000000000000000005079 96.0
TH2_k127_3346442_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 491.0
TH2_k127_3346442_1 radical SAM domain protein K22226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 477.0
TH2_k127_3346442_10 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000004052 226.0
TH2_k127_3346442_11 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000228 185.0
TH2_k127_3346442_12 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000001331 168.0
TH2_k127_3346442_13 SMART Transcription regulator, AsnC-type - - - 0.00000000000000000000000000000000000002129 148.0
TH2_k127_3346442_14 transcriptional regulator, AsnC family - - - 0.00000000000000000000000000000000000003445 149.0
TH2_k127_3346442_15 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000001656 149.0
TH2_k127_3346442_16 Cytochrome c - - - 0.0000000000000003072 90.0
TH2_k127_3346442_17 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000006805 82.0
TH2_k127_3346442_18 COG1596 Periplasmic protein involved in polysaccharide export K01991 - - 0.0000000000002449 79.0
TH2_k127_3346442_19 cytochrome complex assembly - - - 0.000000006608 67.0
TH2_k127_3346442_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 423.0
TH2_k127_3346442_20 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.0000001764 57.0
TH2_k127_3346442_21 - - - - 0.0003791 49.0
TH2_k127_3346442_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 377.0
TH2_k127_3346442_4 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 374.0
TH2_k127_3346442_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 334.0
TH2_k127_3346442_6 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 339.0
TH2_k127_3346442_7 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 303.0
TH2_k127_3346442_8 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000001288 267.0
TH2_k127_3346442_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000009879 229.0
TH2_k127_3358253_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 577.0
TH2_k127_3358253_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 461.0
TH2_k127_3358253_2 Periplasmic binding protein LacI transcriptional regulator K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 368.0
TH2_k127_3358253_3 Belongs to the binding-protein-dependent transport system permease family K10440,K17203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 331.0
TH2_k127_3358253_5 - - - - 0.000000000000000000000000000000000000000000004229 168.0
TH2_k127_3358253_6 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000007392 172.0
TH2_k127_3358253_7 - - - - 0.0000000000000000000003692 97.0
TH2_k127_3358253_8 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000008435 87.0
TH2_k127_3358721_0 FMN-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 291.0
TH2_k127_3358721_1 - K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000593 218.0
TH2_k127_3358721_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000004278 182.0
TH2_k127_3358721_3 Glycosyl hydrolase family 20, catalytic domain - - - 0.000001164 51.0
TH2_k127_3358721_4 Transposase IS200 like K07491 - - 0.0005346 44.0
TH2_k127_3379980_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 604.0
TH2_k127_3379980_1 - - - - 0.0000000000000000000000000000000000000000000006206 169.0
TH2_k127_3379980_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000006388 61.0
TH2_k127_3382556_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000008699 189.0
TH2_k127_33921_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.184e-291 902.0
TH2_k127_33921_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 9.76e-245 773.0
TH2_k127_33921_10 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000001101 216.0
TH2_k127_33921_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000002839 211.0
TH2_k127_33921_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000003143 205.0
TH2_k127_33921_13 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000001838 190.0
TH2_k127_33921_14 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001932 182.0
TH2_k127_33921_15 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000002212 184.0
TH2_k127_33921_16 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000003032 176.0
TH2_k127_33921_17 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000001435 175.0
TH2_k127_33921_18 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000009239 175.0
TH2_k127_33921_19 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001911 166.0
TH2_k127_33921_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.018e-242 766.0
TH2_k127_33921_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000808 162.0
TH2_k127_33921_21 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000025 161.0
TH2_k127_33921_22 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001365 157.0
TH2_k127_33921_23 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000001733 153.0
TH2_k127_33921_24 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000003679 144.0
TH2_k127_33921_25 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000001147 139.0
TH2_k127_33921_26 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000109 124.0
TH2_k127_33921_27 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000006507 126.0
TH2_k127_33921_28 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000006377 122.0
TH2_k127_33921_29 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000001063 100.0
TH2_k127_33921_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 478.0
TH2_k127_33921_30 Ribosomal protein S17 - - - 0.00000000000000000001603 93.0
TH2_k127_33921_31 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000003047 91.0
TH2_k127_33921_32 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000004263 85.0
TH2_k127_33921_33 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000005627 72.0
TH2_k127_33921_34 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000008385 50.0
TH2_k127_33921_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 381.0
TH2_k127_33921_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 348.0
TH2_k127_33921_6 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002118 284.0
TH2_k127_33921_7 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000008448 260.0
TH2_k127_33921_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000209 233.0
TH2_k127_33921_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000008986 225.0
TH2_k127_3394266_0 Belongs to the xylose isomerase family K01805 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 597.0
TH2_k127_3394266_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 324.0
TH2_k127_3394266_2 Xylose operon regulatory protein K02529 - - 0.000000000000000000000000000000000000000000000000000000000005208 222.0
TH2_k127_3394266_3 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000009828 178.0
TH2_k127_3394266_4 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000003062 171.0
TH2_k127_3394266_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000006799 146.0
TH2_k127_3394266_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000001879 126.0
TH2_k127_3396353_0 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 503.0
TH2_k127_3396353_1 haemagglutination activity domain - - - 0.00000000000000000000000000001222 135.0
TH2_k127_3396353_2 Aldo Keto reductase K07079 - - 0.0000000000000003697 80.0
TH2_k127_3403455_0 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000504 214.0
TH2_k127_3403455_1 ATPase or kinase K06925 - - 0.0000000000000000000000000003375 117.0
TH2_k127_3445492_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 479.0
TH2_k127_3445492_1 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000000000000000000000001417 130.0
TH2_k127_3445492_2 nucleotidyltransferase activity - - - 0.000000000000000000000000003104 114.0
TH2_k127_3445492_3 HEPN domain - - - 0.0000000000000002009 84.0
TH2_k127_3468028_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 595.0
TH2_k127_3468028_1 Alcohol dehydrogenase GroES domain protein K12957 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 461.0
TH2_k127_3468028_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 285.0
TH2_k127_3468028_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000001297 229.0
TH2_k127_3468028_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000002491 70.0
TH2_k127_3468028_5 oligosaccharyl transferase activity - - - 0.0000000004455 74.0
TH2_k127_3468028_6 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00003737 50.0
TH2_k127_3476011_0 COG1448 Aspartate tyrosine aromatic aminotransferase K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683 496.0
TH2_k127_3476011_1 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000001473 240.0
TH2_k127_3476011_2 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000004797 196.0
TH2_k127_3476011_3 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000007908 166.0
TH2_k127_3476011_4 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000001524 160.0
TH2_k127_3476011_5 transcriptional regulator K07722 - - 0.00000000000000000000000000000000006528 138.0
TH2_k127_3476011_6 Carbohydrate-selective porin K07267 - - 0.0000000000000000000009509 109.0
TH2_k127_3481998_0 PFAM Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 614.0
TH2_k127_3481998_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009147 548.0
TH2_k127_3481998_2 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 537.0
TH2_k127_3481998_3 Aldo/keto reductase family K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 439.0
TH2_k127_3481998_4 drug transmembrane transporter activity K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 443.0
TH2_k127_3481998_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000115 149.0
TH2_k127_3481998_6 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000001503 83.0
TH2_k127_3481998_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000005859 76.0
TH2_k127_3488972_0 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 436.0
TH2_k127_3488972_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 294.0
TH2_k127_3488972_2 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000001364 228.0
TH2_k127_3488972_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000004189 190.0
TH2_k127_3496729_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 451.0
TH2_k127_3496729_1 Outer membrane protein assembly complex, YaeT protein K07277 - - 0.000000000000000000000000000000000000000000000000000000004114 218.0
TH2_k127_3496729_2 Single-stranded DNA-binding protein K03111 - - 0.00000000000000000000000000000000000004483 147.0
TH2_k127_3496729_3 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000002605 120.0
TH2_k127_3496729_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000001168 76.0
TH2_k127_3501308_0 UPF0210 protein K09157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 532.0
TH2_k127_3501308_1 Belongs to the glycosyl hydrolase 2 family K01192 - 3.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 445.0
TH2_k127_3501308_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 422.0
TH2_k127_3501308_4 ACT domain protein K07166 - - 0.0000000000000000005736 89.0
TH2_k127_3501308_5 Type II secretion system (T2SS), protein K - - - 0.0002923 53.0
TH2_k127_3501590_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.871e-242 766.0
TH2_k127_3501590_1 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 477.0
TH2_k127_3501590_2 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation K16899 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000001368 262.0
TH2_k127_352309_0 asparagine synthase K01953 - 6.3.5.4 1.641e-223 710.0
TH2_k127_352309_1 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 436.0
TH2_k127_352309_2 Phosphopantetheine attachment site - - - 0.0000000000000000000006426 97.0
TH2_k127_352309_3 self proteolysis K04771 - 3.4.21.107 0.00002278 48.0
TH2_k127_3530638_0 Evidence 4 Homologs of previously reported genes of K06990 - - 0.000000000000000000000000000000000000000000000000000000000009543 217.0
TH2_k127_3530638_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) - - - 0.0000000000000000000000000000000000000000000000217 175.0
TH2_k127_3530638_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000003397 146.0
TH2_k127_3530638_4 positive regulation of growth - - - 0.000000001915 61.0
TH2_k127_3533633_0 carbohydrate binding - - - 1.918e-225 725.0
TH2_k127_3533633_1 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000002871 102.0
TH2_k127_3547394_0 TIGRFAM amino acid carrier protein K03310 - - 1.541e-196 621.0
TH2_k127_3547394_1 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 391.0
TH2_k127_3547394_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000008621 136.0
TH2_k127_3547394_4 PAC2 family K07159 - - 0.000000000000000000000001886 113.0
TH2_k127_3547394_5 Protein of unknown function (DUF3568) - - - 0.0000000000003719 74.0
TH2_k127_3547394_7 Prokaryotic N-terminal methylation motif K02650,K02655 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00009202 51.0
TH2_k127_3581744_0 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 428.0
TH2_k127_3581744_1 - - - - 0.0000000000000000000000000000000000001484 149.0
TH2_k127_3581744_2 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000002542 126.0
TH2_k127_3581744_3 - - - - 0.00001675 50.0
TH2_k127_3581744_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0004604 43.0
TH2_k127_3591526_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 415.0
TH2_k127_3591526_1 Glycogen debranching enzyme K03931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009449 406.0
TH2_k127_3591526_2 DNA methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 306.0
TH2_k127_3591526_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001979 267.0
TH2_k127_3601059_0 Hypothetical glycosyl hydrolase 6 - - - 6.478e-252 794.0
TH2_k127_3601059_2 symporter activity K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 413.0
TH2_k127_3601059_3 Transcriptional regulator, AraC family K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002246 279.0
TH2_k127_3601059_4 alpha-galactosidase - - - 0.000000000000000000000000000000004481 139.0
TH2_k127_3610256_0 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.00000000000000000000000000000000000000000000000000003619 201.0
TH2_k127_3610256_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000006148 112.0
TH2_k127_3610256_2 protein conserved in bacteria K09928 - - 0.000000000000005292 79.0
TH2_k127_3610697_0 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000008729 241.0
TH2_k127_3610697_1 Belongs to the PdxA family K22024 - 1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000206 194.0
TH2_k127_3610697_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000008483 199.0
TH2_k127_3622620_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 400.0
TH2_k127_3622620_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000008199 168.0
TH2_k127_3622620_2 type II secretion system protein E K02652 - - 0.000007411 49.0
TH2_k127_3625828_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 524.0
TH2_k127_3625828_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 338.0
TH2_k127_3625828_2 Pfam:N_methyl_2 K02456 - - 0.00000000000000000000002616 107.0
TH2_k127_3625828_3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin - - - 0.0000000000000000003692 101.0
TH2_k127_3631501_0 MMPL family K07003 - - 5.296e-259 823.0
TH2_k127_3631501_1 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000003043 237.0
TH2_k127_3631501_2 PFAM toluene tolerance K07323 - - 0.00000000000000000000000000000000007994 141.0
TH2_k127_3654100_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1429.0
TH2_k127_3654100_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1079.0
TH2_k127_3654100_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000003051 137.0
TH2_k127_3654100_3 - - - - 0.00002161 46.0
TH2_k127_369038_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 4.228e-205 655.0
TH2_k127_369038_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 450.0
TH2_k127_369038_2 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000002615 188.0
TH2_k127_369038_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000003039 121.0
TH2_k127_369038_4 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.0000000000000000112 95.0
TH2_k127_369038_5 deoxyhypusine monooxygenase activity - - - 0.000000000000000683 81.0
TH2_k127_3723492_0 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 585.0
TH2_k127_3723492_1 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 555.0
TH2_k127_3723492_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 475.0
TH2_k127_3723492_3 Uncharacterised protein family (UPF0014) K02069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000021 270.0
TH2_k127_3723492_4 Pfam ABC K02068 - - 0.00000000000000000000000000000000000000000000000003211 188.0
TH2_k127_3726895_0 cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 426.0
TH2_k127_3726895_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 427.0
TH2_k127_3726895_10 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000004533 79.0
TH2_k127_3726895_11 - - - - 0.000001518 56.0
TH2_k127_3726895_12 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000006386 53.0
TH2_k127_3726895_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 375.0
TH2_k127_3726895_3 Serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 342.0
TH2_k127_3726895_4 O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004589 268.0
TH2_k127_3726895_5 COG2406 Protein distantly related to bacterial ferritins K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001335 265.0
TH2_k127_3726895_6 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000004221 200.0
TH2_k127_3726895_7 Transcriptional regulator - - - 0.000000000000000000000000000000002539 134.0
TH2_k127_3726895_8 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000003578 130.0
TH2_k127_3726895_9 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000001443 100.0
TH2_k127_3771406_0 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 550.0
TH2_k127_3771406_1 Lysine-2,3-aminomutase K01843,K19814 - 5.4.3.2,5.4.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 437.0
TH2_k127_3771406_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000002054 81.0
TH2_k127_3771406_3 Bacterial regulatory proteins, tetR family - - - 0.0000000001048 70.0
TH2_k127_3771406_4 K -dependent Na Ca exchanger family protein K07301 - - 0.00009728 45.0
TH2_k127_386204_0 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 437.0
TH2_k127_386204_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 344.0
TH2_k127_386204_10 ADP-ribosylglycohydrolase - - - 0.000001031 63.0
TH2_k127_386204_2 ABC-type (unclassified) transport system ATPase K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 287.0
TH2_k127_386204_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 294.0
TH2_k127_386204_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000002128 235.0
TH2_k127_386204_5 Transcriptional regulator with PAS PAC sensors, AraC family - - - 0.00000000000000000000000000000000000000000000000000000000000001412 225.0
TH2_k127_386204_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000009429 214.0
TH2_k127_386204_7 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000007087 166.0
TH2_k127_386204_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000009272 150.0
TH2_k127_386204_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000001831 144.0
TH2_k127_3875928_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 424.0
TH2_k127_3875928_1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 327.0
TH2_k127_3875928_2 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000007433 209.0
TH2_k127_3875928_3 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000003274 176.0
TH2_k127_3889202_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 1.764e-254 797.0
TH2_k127_3889202_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.747e-219 694.0
TH2_k127_3889202_10 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000132 286.0
TH2_k127_3889202_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006146 268.0
TH2_k127_3889202_12 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002828 255.0
TH2_k127_3889202_13 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000003453 239.0
TH2_k127_3889202_14 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000001358 249.0
TH2_k127_3889202_15 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000003098 231.0
TH2_k127_3889202_16 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000008966 223.0
TH2_k127_3889202_17 - - - - 0.00000000000000000000000000000000000000000000000000000009119 204.0
TH2_k127_3889202_18 Thioredoxin-like [2Fe-2S] ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000005084 197.0
TH2_k127_3889202_19 Ferredoxin K00335,K17992 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000004846 156.0
TH2_k127_3889202_2 iron-sulfur cluster assembly K00336,K18332 - 1.12.1.3,1.6.5.3 4.25e-216 685.0
TH2_k127_3889202_20 cheY-homologous receiver domain K07658 - - 0.000000000000000000000000000000000257 135.0
TH2_k127_3889202_21 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000003044 136.0
TH2_k127_3889202_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 520.0
TH2_k127_3889202_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 505.0
TH2_k127_3889202_5 PFAM AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 456.0
TH2_k127_3889202_6 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 460.0
TH2_k127_3889202_7 Belongs to the purine-cytosine permease (2.A.39) family K10974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 381.0
TH2_k127_3889202_8 formate dehydrogenase K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 337.0
TH2_k127_3889202_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 333.0
TH2_k127_3909669_0 COG4992 Ornithine acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 493.0
TH2_k127_3909669_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 331.0
TH2_k127_3909669_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 322.0
TH2_k127_3909669_3 PFAM Cytochrome c assembly protein K02195 - - 0.00000000000000000000000000000001903 134.0
TH2_k127_3909669_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000307 45.0
TH2_k127_4041423_0 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 298.0
TH2_k127_4041423_1 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000000000000005291 197.0
TH2_k127_4041423_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000003842 62.0
TH2_k127_4043833_0 PFAM hexokinase K00844 - 2.7.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 445.0
TH2_k127_4043833_1 - K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 412.0
TH2_k127_4043833_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 385.0
TH2_k127_4043833_3 integrase domain protein SAM domain protein K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002762 275.0
TH2_k127_4043833_4 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000001418 191.0
TH2_k127_4043906_0 PFAM Glycosyl hydrolases family 38 C-terminal domain - - - 3.196e-283 892.0
TH2_k127_4043906_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 474.0
TH2_k127_4043906_2 ZIP Zinc transporter K07238,K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 394.0
TH2_k127_4043906_3 Pseudouridine synthase K06179,K06180 - 5.4.99.23,5.4.99.24 0.0000000000000000000000000000000000000215 156.0
TH2_k127_4043906_4 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000003203 65.0
TH2_k127_4112728_0 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000002893 241.0
TH2_k127_4112728_1 Prokaryotic N-terminal methylation motif K02650 - - 0.000002653 55.0
TH2_k127_4193506_0 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 311.0
TH2_k127_4193506_1 Protein of unknown function (DUF503) K09764 - - 0.000000000000000003572 91.0
TH2_k127_4193506_2 - - - - 0.00000000001112 69.0
TH2_k127_4193506_3 Protein of unknown function (DUF3485) - - - 0.00000003762 63.0
TH2_k127_4260197_0 60 kDa outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 344.0
TH2_k127_4260197_1 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000007982 234.0
TH2_k127_4260197_2 Passenger-associated-transport-repeat - - - 0.0000003773 60.0
TH2_k127_4283063_0 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 353.0
TH2_k127_4283063_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000009652 220.0
TH2_k127_4283063_2 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000001481 207.0
TH2_k127_4283063_3 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.0000000000000000000000000000000000000001315 163.0
TH2_k127_4283063_4 PFAM lipopolysaccharide biosynthesis protein K16554 - - 0.0000000000000000000000000000000000000002615 161.0
TH2_k127_4350931_0 TIGRFAM electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003204 251.0
TH2_k127_4350931_1 - - - - 0.0000000000000000000000000000000000000000000000000000000002128 209.0
TH2_k127_4350931_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000009056 180.0
TH2_k127_4350931_3 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000001628 92.0
TH2_k127_43600_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 437.0
TH2_k127_43600_1 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 296.0
TH2_k127_43600_3 Isochorismatase family - - - 0.0000000000003947 70.0
TH2_k127_437734_0 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02652 - - 1.06e-200 640.0
TH2_k127_437734_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 611.0
TH2_k127_437734_10 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000004142 96.0
TH2_k127_437734_11 pilus assembly protein K02662 - - 0.00000000000000000106 92.0
TH2_k127_437734_12 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000008505 77.0
TH2_k127_437734_13 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) - - - 0.00000000677 62.0
TH2_k127_437734_14 protein N-acetylglucosaminyltransferase activity K16531 GO:0000226,GO:0000242,GO:0003674,GO:0003774,GO:0003777,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005815,GO:0005856,GO:0005929,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007098,GO:0008092,GO:0008150,GO:0009987,GO:0015630,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022402,GO:0022607,GO:0030030,GO:0030031,GO:0031023,GO:0032991,GO:0034452,GO:0034464,GO:0036064,GO:0042995,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044422,GO:0044424,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044450,GO:0044463,GO:0044464,GO:0044782,GO:0060271,GO:0070925,GO:0071840,GO:0120025,GO:0120031,GO:0120036,GO:0120038 - 0.00000001752 66.0
TH2_k127_437734_16 PFAM Pilus assembly protein PilO K02664 - - 0.00001921 53.0
TH2_k127_437734_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 533.0
TH2_k127_437734_3 Belongs to the GSP D family K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002574 292.0
TH2_k127_437734_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000004865 246.0
TH2_k127_437734_5 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000405 237.0
TH2_k127_437734_6 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000456 231.0
TH2_k127_437734_7 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000001019 159.0
TH2_k127_437734_8 nitrogen fixation - - - 0.0000000000000000000000000000000000001224 146.0
TH2_k127_437734_9 PFAM response regulator receiver K11329 - - 0.0000000000000000000000000005649 119.0
TH2_k127_4462235_0 Hydrolyase tartrate alpha subunit fumarate domain protein Fe-S type K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 308.0
TH2_k127_4462235_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000004317 148.0
TH2_k127_4462235_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.00006235 53.0
TH2_k127_4462235_3 - - - - 0.0006973 45.0
TH2_k127_4477448_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.064e-208 656.0
TH2_k127_4477448_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 9.798e-197 625.0
TH2_k127_4477448_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000005549 115.0
TH2_k127_4477448_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000007389 97.0
TH2_k127_4477448_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000005609 80.0
TH2_k127_4477448_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000004846 75.0
TH2_k127_4477448_15 PQQ enzyme repeat - - - 0.00000002186 66.0
TH2_k127_4477448_16 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00001293 55.0
TH2_k127_4477448_17 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0003627 47.0
TH2_k127_4477448_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 551.0
TH2_k127_4477448_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 441.0
TH2_k127_4477448_4 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000001099 231.0
TH2_k127_4477448_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000007573 188.0
TH2_k127_4477448_6 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000001539 183.0
TH2_k127_4477448_7 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271,K12961 - 5.3.1.28 0.00000000000000000000000000000000000000000000003274 176.0
TH2_k127_4477448_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000001855 160.0
TH2_k127_4477448_9 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000002703 145.0
TH2_k127_4484013_0 Hypothetical glycosyl hydrolase 6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 584.0
TH2_k127_4484013_1 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 510.0
TH2_k127_4484013_2 domain, Protein K21493 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 318.0
TH2_k127_4484013_3 HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000001228 76.0
TH2_k127_4484013_4 hydrolase family 65, central catalytic K00691 - 2.4.1.8 0.0001847 45.0
TH2_k127_4489396_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 3.129e-201 652.0
TH2_k127_4489396_1 SMART Pyrrolo-quinoline quinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003557 297.0
TH2_k127_4489396_2 FMN-binding domain protein - - - 0.00000000000000000000000002117 114.0
TH2_k127_4498872_0 Belongs to the ribulokinase family K00853 - 2.7.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 398.0
TH2_k127_4498872_1 Major facilitator Superfamily K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001723 292.0
TH2_k127_4498872_2 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000008978 89.0
TH2_k127_4500208_0 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000612 195.0
TH2_k127_4500208_1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000002448 134.0
TH2_k127_4505373_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 507.0
TH2_k127_4505373_1 PFAM response regulator receiver K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 302.0
TH2_k127_4505373_2 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000006772 74.0
TH2_k127_4514487_0 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000005498 274.0
TH2_k127_4514487_1 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 0.000000000000000000000000000000000000000000000000000000158 203.0
TH2_k127_4514487_2 - - - - 0.0000000000000000000000000000000000000000000000000003611 191.0
TH2_k127_4514487_3 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.0000000000000000000000004487 107.0
TH2_k127_4526365_0 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 321.0
TH2_k127_4526365_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000155 273.0
TH2_k127_4526365_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000001859 246.0
TH2_k127_4526365_3 PFAM Transcription termination factor nusG K05785 - - 0.000000000000000000000000000001555 127.0
TH2_k127_4526365_4 - - - - 0.000000000157 66.0
TH2_k127_4526365_5 - - - - 0.0008835 45.0
TH2_k127_4535517_0 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000001124 226.0
TH2_k127_4535517_1 FtsX-like permease family - - - 0.000000000000000000000000000000000005336 150.0
TH2_k127_4535517_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000007618 75.0
TH2_k127_4544238_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 308.0
TH2_k127_4544238_1 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000143 235.0
TH2_k127_4544238_2 Cellulose biosynthesis protein BcsQ K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000003131 233.0
TH2_k127_4544238_3 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000001118 167.0
TH2_k127_4544238_4 - - - - 0.00000000000001361 85.0
TH2_k127_4544238_5 transcriptional - - - 0.00000004199 57.0
TH2_k127_4552305_0 In Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS K03150 - 4.1.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 379.0
TH2_k127_4552305_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 370.0
TH2_k127_4552305_2 PDZ domain (Also known as DHR K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000005812 256.0
TH2_k127_4555820_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 1429.0
TH2_k127_4555820_1 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 533.0
TH2_k127_4555820_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 471.0
TH2_k127_4568093_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 437.0
TH2_k127_4568093_1 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 292.0
TH2_k127_4568093_2 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000000000000000000000005283 214.0
TH2_k127_4568093_3 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000003977 184.0
TH2_k127_4568093_4 PFAM metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000007392 167.0
TH2_k127_4568093_5 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000002974 159.0
TH2_k127_4568093_6 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000000003644 89.0
TH2_k127_4568093_7 - - - - 0.000003122 55.0
TH2_k127_4579286_0 COG1077 Actin-like ATPase involved in cell morphogenesis K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 507.0
TH2_k127_4579286_1 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.00000000000000000000000000000000000000003019 174.0
TH2_k127_4579286_2 Involved in formation and maintenance of cell shape K03570 - - 0.000000004874 66.0
TH2_k127_4647743_0 Carbohydrate kinase, FGGY family protein K00854 - 2.7.1.17 4.127e-194 617.0
TH2_k127_4647743_1 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000009118 216.0
TH2_k127_4647743_2 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000002458 187.0
TH2_k127_4647743_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000002747 171.0
TH2_k127_4647743_4 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001506 149.0
TH2_k127_4647743_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0006911 42.0
TH2_k127_4659886_0 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 503.0
TH2_k127_4659886_1 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 434.0
TH2_k127_4659886_2 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 353.0
TH2_k127_4659886_4 carbon utilization K02664 - - 0.000000000000000000003441 100.0
TH2_k127_4674342_0 PFAM Nickel-dependent hydrogenase, large subunit K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 435.0
TH2_k127_4674342_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000001339 227.0
TH2_k127_4674342_2 Scavenger mRNA decapping enzyme C-term binding - - - 0.00000000000000000005474 92.0
TH2_k127_4674342_3 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000001223 90.0
TH2_k127_4674342_4 S-methyltransferase activity K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.000000005642 70.0
TH2_k127_4698818_0 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 499.0
TH2_k127_4698818_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 362.0
TH2_k127_4698818_10 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000002525 68.0
TH2_k127_4698818_2 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 - 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 348.0
TH2_k127_4698818_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000007952 234.0
TH2_k127_4698818_4 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000001958 190.0
TH2_k127_4698818_5 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000006098 146.0
TH2_k127_4698818_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000002497 146.0
TH2_k127_4698818_7 protein with conserved CXXC pairs K19411 - - 0.000000000000000000000000007026 116.0
TH2_k127_4698818_8 3D domain - - - 0.000000000000000002827 95.0
TH2_k127_4698818_9 Glycosyl transferase 4-like - - - 0.0000000000149 76.0
TH2_k127_4720991_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.547e-229 723.0
TH2_k127_4720991_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 307.0
TH2_k127_4720991_2 response regulator receiver K02488 - 2.7.7.65 0.000000000000000000000000000000000000000003037 160.0
TH2_k127_4720991_3 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000207 114.0
TH2_k127_4720991_4 Subtilase family - - - 0.000000000000003491 89.0
TH2_k127_4720991_5 Tetratricopeptide repeat - - - 0.000000000135 74.0
TH2_k127_4720991_7 PFAM Cupin 2, conserved barrel domain protein - - - 0.00002074 47.0
TH2_k127_4756104_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.567e-223 705.0
TH2_k127_4756104_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.547e-203 646.0
TH2_k127_4756104_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 382.0
TH2_k127_4756104_3 Dna alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004323 262.0
TH2_k127_4756104_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000001938 131.0
TH2_k127_4756104_5 Regulatory protein, FmdB family - - - 0.00000000000000000000000000007593 119.0
TH2_k127_4756104_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000001432 114.0
TH2_k127_4756104_7 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000001685 98.0
TH2_k127_4797718_0 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.101e-207 655.0
TH2_k127_4797718_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 371.0
TH2_k127_4797718_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000002071 213.0
TH2_k127_4797718_3 peptidase U32 K08303 - - 0.0000000000000000000000000000000000002825 144.0
TH2_k127_4797718_4 ATPase, AAA superfamily K07133 - - 0.000000000000000000000000000000001511 146.0
TH2_k127_4797718_5 histidine kinase A domain protein - - - 0.00000000000000000000000000000004008 141.0
TH2_k127_4797718_6 helix_turn_helix, Lux Regulon - - - 0.00000002633 66.0
TH2_k127_4896200_0 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 426.0
TH2_k127_4896200_1 metallopeptidase activity K01179,K04618,K12287,K12548 - 1.1.3.9,3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 317.0
TH2_k127_4896200_2 PEP-CTERM motif - - - 0.000000000000000000000009013 108.0
TH2_k127_4896200_3 Belongs to the 'phage' integrase family - - - 0.000000000000002445 77.0
TH2_k127_4896200_4 Integrase - - - 0.0000000000002318 74.0
TH2_k127_4896200_5 L-rhamnose-proton symport protein (RhaT) K02856 - - 0.0007427 42.0
TH2_k127_49148_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.144e-252 807.0
TH2_k127_49148_1 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001056 277.0
TH2_k127_49148_2 Transposase IS200 like - - - 0.000000000000000000000000000009566 121.0
TH2_k127_4930063_0 PFAM FAD dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 624.0
TH2_k127_4930063_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003859 258.0
TH2_k127_4930063_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07291 - 2.7.8.34 0.000000000000000000000000000000000000000000000000000000000000000003626 232.0
TH2_k127_4930063_3 retrograde transport, endosome to Golgi - - - 0.0000001621 60.0
TH2_k127_4930960_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044237,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0098809,GO:1901363 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 529.0
TH2_k127_4930960_1 cytochrome c nitrate reductase, small subunit K15876 - - 0.00000000000000000000000000000000000000000000005791 175.0
TH2_k127_4930960_2 - - - - 0.000000000000000000000000000000009162 133.0
TH2_k127_4934361_0 Histidine Phosphotransfer domain K02488,K11443 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 532.0
TH2_k127_4934361_1 PFAM TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 397.0
TH2_k127_4934361_2 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000008085 247.0
TH2_k127_4934361_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000007662 132.0
TH2_k127_4961137_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.347e-226 725.0
TH2_k127_4961137_1 Galactose mutarotase-like K01187,K01811 - 3.2.1.177,3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 538.0
TH2_k127_4961137_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 305.0
TH2_k127_4961137_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000001121 276.0
TH2_k127_4961137_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000004094 208.0
TH2_k127_4961137_5 glycosyl transferase family 2 K20444 - - 0.0000001939 61.0
TH2_k127_5026320_0 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000001044 157.0
TH2_k127_5026320_1 Sulfatase - - - 0.000000000000000000000002045 110.0
TH2_k127_5026320_2 Tetratricopeptide repeat - - - 0.00000008582 64.0
TH2_k127_505445_0 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000000000000158 113.0
TH2_k127_505445_1 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000001139 81.0
TH2_k127_505445_2 virulence factor Mce family protein K02067 - - 0.0000000000004655 79.0
TH2_k127_505445_3 Type II secretion system K02653 - - 0.000000005748 63.0
TH2_k127_505445_4 helix_turn_helix, mercury resistance - - - 0.000001625 53.0
TH2_k127_5097557_0 glucosamine-6-phosphate deaminase activity K01057,K02564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.1.1.31,3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 390.0
TH2_k127_5097557_1 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000001503 193.0
TH2_k127_5097557_2 - - - - 0.00000000000000000000000004849 111.0
TH2_k127_5097557_4 - - - - 0.000000000000002727 76.0
TH2_k127_5097557_5 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.00000000000001875 78.0
TH2_k127_5097557_6 - - - - 0.000000009564 56.0
TH2_k127_5097557_7 CAAX protease self-immunity - - - 0.00000003808 64.0
TH2_k127_51464_0 Methyltransferase domain K22309 - 2.1.1.344 0.00000000000000000000000000000000000000000000000005151 185.0
TH2_k127_51464_1 mannitol metabolic process K00009 - 1.1.1.17 0.00000000000000000000000000000000000000000000001658 179.0
TH2_k127_51464_2 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000001053 143.0
TH2_k127_51464_3 DNA recombination K03497,K13582 - - 0.0000000000000000000001476 112.0
TH2_k127_5190851_0 symporter activity K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 428.0
TH2_k127_5190851_1 Domain of unknown function (DUF4832) - - - 0.00000000000000001313 98.0
TH2_k127_5190851_2 cobalamin binding - - - 0.00000000000000004 84.0
TH2_k127_5243147_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 3.838e-205 655.0
TH2_k127_5243147_1 PFAM Phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 501.0
TH2_k127_5243147_2 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000009226 166.0
TH2_k127_5243147_3 Nitrite and sulphite reductase 4Fe-4S K00392 - 1.8.7.1 0.00000000002082 70.0
TH2_k127_5261107_0 Pyruvate carboxyltransferase - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 556.0
TH2_k127_5261107_1 SMP-30 Gluconolaconase LRE-like K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 310.0
TH2_k127_5261107_2 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000002902 202.0
TH2_k127_5261107_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000629 93.0
TH2_k127_5261107_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025,K08723 - 3.1.3.5 0.000000000000000154 89.0
TH2_k127_5261107_6 Response regulator receiver K03413 - - 0.0004608 48.0
TH2_k127_5584070_0 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 592.0
TH2_k127_5584070_1 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 466.0
TH2_k127_5584070_2 Nucleic acid binding K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009794 278.0
TH2_k127_5584070_3 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation K16899 - 3.6.4.12 0.000000000000000000000000000007728 126.0
TH2_k127_5584070_4 Protein of unknown function (DUF2089) - - - 0.00000000000000000000000000005581 119.0
TH2_k127_5584070_5 - - - - 0.000000000000000000000000003695 119.0
TH2_k127_5584070_6 - - - - 0.000000000000000000000003372 108.0
TH2_k127_5584652_0 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 407.0
TH2_k127_5584652_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 286.0
TH2_k127_5584652_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000001183 221.0
TH2_k127_5584652_3 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.0000000000000000000000000000000000000000003814 165.0
TH2_k127_5584652_4 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000002129 137.0
TH2_k127_5584906_0 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008602 285.0
TH2_k127_5584906_1 of the beta-lactamase K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000003173 224.0
TH2_k127_5584906_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000002273 221.0
TH2_k127_5584906_3 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000002413 159.0
TH2_k127_5584906_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000002598 148.0
TH2_k127_5584906_5 metal cluster binding K06940 - - 0.000000000000000000005789 99.0
TH2_k127_5584906_6 DNA photolyase K01669 - 4.1.99.3 0.000000000000001986 78.0
TH2_k127_5584906_7 photo-lyase K01669 GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363 4.1.99.3 0.00000005049 54.0
TH2_k127_5584906_8 Evidence 4 Homologs of previously reported genes of - - - 0.00000007878 64.0
TH2_k127_5590150_0 Glycogen debranching enzyme - - - 6.962e-299 924.0
TH2_k127_5590150_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 6.938e-282 878.0
TH2_k127_5590150_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 5.435e-268 840.0
TH2_k127_5590150_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 512.0
TH2_k127_5590150_4 iron-sulfur cluster assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 511.0
TH2_k127_5590150_5 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 319.0
TH2_k127_5590150_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000003845 210.0
TH2_k127_5590150_8 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000004216 199.0
TH2_k127_5590150_9 PFAM Sporulation stage II, protein E C-terminal - - - 0.0000000000000000000000000000000000000000001352 173.0
TH2_k127_5605980_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 448.0
TH2_k127_5605980_1 Glucose dehydrogenase C-terminus K00008,K05351 - 1.1.1.14,1.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 411.0
TH2_k127_5605980_2 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000109 126.0
TH2_k127_5605980_3 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000001016 100.0
TH2_k127_5605980_4 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000004216 68.0
TH2_k127_5606302_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006684 488.0
TH2_k127_5606302_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 477.0
TH2_k127_5606302_2 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000002042 158.0
TH2_k127_5606302_3 Late embryogenesis abundant protein - - - 0.00001818 50.0
TH2_k127_5615069_0 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 306.0
TH2_k127_5615069_1 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003993 278.0
TH2_k127_5615069_2 Belongs to the SpoVG family K06412 - - 0.00000000000000000000000000000000000000000000000000006031 189.0
TH2_k127_5615069_3 metal cluster binding K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.000000000000000000000000000000000000000000000000003799 191.0
TH2_k127_5615069_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000005077 186.0
TH2_k127_5615069_5 GDP-mannose mannosyl hydrolase activity K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000009913 175.0
TH2_k127_5615069_6 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000001433 99.0
TH2_k127_5615069_7 Penicillinase repressor - - - 0.00000000000000000021 93.0
TH2_k127_5615069_8 Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle K14211 GO:0001101,GO:0001568,GO:0001666,GO:0001944,GO:0001974,GO:0003007,GO:0003008,GO:0003013,GO:0003151,GO:0003170,GO:0003176,GO:0003179,GO:0003180,GO:0003674,GO:0005198,GO:0005201,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007154,GO:0007275,GO:0007507,GO:0007517,GO:0007519,GO:0007568,GO:0007584,GO:0007585,GO:0008015,GO:0008064,GO:0008150,GO:0008283,GO:0009410,GO:0009605,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009887,GO:0009888,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0014070,GO:0014706,GO:0016043,GO:0022607,GO:0030023,GO:0030029,GO:0030036,GO:0030038,GO:0030198,GO:0030832,GO:0030833,GO:0031012,GO:0031032,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0031960,GO:0032271,GO:0032501,GO:0032502,GO:0032526,GO:0032535,GO:0032870,GO:0032956,GO:0032970,GO:0033043,GO:0033273,GO:0033554,GO:0033591,GO:0033993,GO:0034284,GO:0035690,GO:0035904,GO:0036293,GO:0036294,GO:0036296,GO:0042221,GO:0042493,GO:0043062,GO:0043149,GO:0043254,GO:0044085,GO:0044087,GO:0044344,GO:0044420,GO:0044421,GO:0046688,GO:0048251,GO:0048513,GO:0048545,GO:0048731,GO:0048771,GO:0048856,GO:0050789,GO:0050794,GO:0050840,GO:0050896,GO:0051017,GO:0051128,GO:0051384,GO:0051493,GO:0051716,GO:0055093,GO:0060537,GO:0060538,GO:0060840,GO:0061061,GO:0061572,GO:0065007,GO:0065008,GO:0070482,GO:0070848,GO:0070887,GO:0071229,GO:0071241,GO:0071248,GO:0071280,GO:0071295,GO:0071298,GO:0071300,GO:0071310,GO:0071322,GO:0071326,GO:0071363,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071453,GO:0071456,GO:0071466,GO:0071495,GO:0071496,GO:0071548,GO:0071549,GO:0071559,GO:0071560,GO:0071774,GO:0071840,GO:0071953,GO:0072358,GO:0072359,GO:0085029,GO:0090066,GO:0097327,GO:0097435,GO:0097493,GO:0110053,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1902903,GO:1905314 - 0.0000000002361 63.0
TH2_k127_5625323_0 PFAM Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1768.0
TH2_k127_5625323_1 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1174.0
TH2_k127_5625323_10 PFAM Rh family protein ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 498.0
TH2_k127_5625323_11 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 494.0
TH2_k127_5625323_12 PFAM MltA domain protein K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 472.0
TH2_k127_5625323_13 Domain of unknown function (DUF4954) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 481.0
TH2_k127_5625323_14 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 344.0
TH2_k127_5625323_15 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 306.0
TH2_k127_5625323_16 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 316.0
TH2_k127_5625323_17 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009899 275.0
TH2_k127_5625323_18 Divalent cation transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000038 254.0
TH2_k127_5625323_19 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.00000000000000000000000000000000000000000000000000000000000004007 220.0
TH2_k127_5625323_2 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 6.926e-304 947.0
TH2_k127_5625323_20 Belongs to the SUA5 family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000002893 223.0
TH2_k127_5625323_21 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000003835 165.0
TH2_k127_5625323_22 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000637 162.0
TH2_k127_5625323_23 single-species biofilm formation - - - 0.0000000000000000000000000000000000000000007562 161.0
TH2_k127_5625323_24 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.00000000000000000000000000000000000000001669 158.0
TH2_k127_5625323_25 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000005562 152.0
TH2_k127_5625323_26 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000000002987 146.0
TH2_k127_5625323_27 - - - - 0.00000000000000000000000000000000008795 144.0
TH2_k127_5625323_28 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000004455 119.0
TH2_k127_5625323_29 PFAM RNA recognition motif - - - 0.00000000000000000000000008977 111.0
TH2_k127_5625323_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.595e-208 666.0
TH2_k127_5625323_30 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000003127 96.0
TH2_k127_5625323_32 - - - - 0.0000000007154 62.0
TH2_k127_5625323_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 6.311e-202 645.0
TH2_k127_5625323_5 'glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 591.0
TH2_k127_5625323_6 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 537.0
TH2_k127_5625323_7 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 534.0
TH2_k127_5625323_8 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 529.0
TH2_k127_5625323_9 transcription initiation from RNA polymerase III promoter K03022 GO:0000228,GO:0000428,GO:0000785,GO:0000790,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005666,GO:0005694,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006139,GO:0006351,GO:0006352,GO:0006383,GO:0006384,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009304,GO:0009987,GO:0010467,GO:0015630,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0042797,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0046483,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0098781,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 504.0
TH2_k127_5627884_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 394.0
TH2_k127_5627884_1 N-terminal domain of unknown function (DUF4140) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000142 265.0
TH2_k127_5627884_2 PQQ enzyme repeat - - - 0.000000000000000000000003234 112.0
TH2_k127_5627884_3 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000001225 94.0
TH2_k127_5629043_0 Glycosyl hydrolases family 38 C-terminal domain K15524 - 3.2.1.170 3.878e-257 824.0
TH2_k127_5629043_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.641e-207 666.0
TH2_k127_5629043_2 MreB/Mbl protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 402.0
TH2_k127_5629043_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 365.0
TH2_k127_5629043_4 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000005958 192.0
TH2_k127_5629043_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000009291 128.0
TH2_k127_5629043_6 - - - - 0.00001159 57.0
TH2_k127_5645120_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.921e-227 712.0
TH2_k127_5645120_1 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005942 329.0
TH2_k127_5645120_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 333.0
TH2_k127_5645120_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000415 216.0
TH2_k127_5645120_4 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000101 182.0
TH2_k127_5645120_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000001159 140.0
TH2_k127_5645120_6 - - - - 0.0000000000000000000000000001385 124.0
TH2_k127_5645120_7 Psort location Cytoplasmic, score - - - 0.0000000000007628 77.0
TH2_k127_5645120_8 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000005184 71.0
TH2_k127_5646105_1 PFAM glycosyl transferase family 2 K20444 - - 0.0000000000000000000000000001013 132.0
TH2_k127_5646105_2 PFAM TPR repeat-containing protein - - - 0.000000000000000000001023 102.0
TH2_k127_5646105_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family K05928 - 2.1.1.95 0.0005024 51.0
TH2_k127_5646913_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1658.0
TH2_k127_5646913_1 COG1283 Na phosphate symporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 511.0
TH2_k127_5646913_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 301.0
TH2_k127_5646913_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 292.0
TH2_k127_5646913_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001388 250.0
TH2_k127_5646913_5 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000001561 205.0
TH2_k127_5646913_6 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000003003 175.0
TH2_k127_5646913_7 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000004219 147.0
TH2_k127_5646913_8 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000002123 77.0
TH2_k127_5646913_9 Tetratricopeptide repeat - - - 0.000009551 59.0
TH2_k127_5649892_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1021.0
TH2_k127_5649892_1 metalloendopeptidase activity K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 381.0
TH2_k127_5649892_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000002735 233.0
TH2_k127_5649892_3 Transcription factor zinc-finger K09981 - - 0.000001867 51.0
TH2_k127_5649892_4 Peptidase C39 family - - - 0.00004114 54.0
TH2_k127_5653411_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 623.0
TH2_k127_5653411_1 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 471.0
TH2_k127_5653411_2 Amino-transferase class IV - - - 0.0000000000000000000000000000000000000000000000000001054 196.0
TH2_k127_5653411_3 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000002698 127.0
TH2_k127_5653411_4 Lipopolysaccharide-assembly - - - 0.0000000000000000000003708 103.0
TH2_k127_5653411_5 Tetratricopeptide TPR_2 repeat protein K05807 - - 0.00000000000007119 83.0
TH2_k127_5653411_6 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000002483 69.0
TH2_k127_5653411_7 Nucleotidyltransferase domain - - - 0.00000005386 58.0
TH2_k127_56589_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 7.996e-229 721.0
TH2_k127_56589_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 368.0
TH2_k127_56589_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000003035 269.0
TH2_k127_56589_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000002334 136.0
TH2_k127_56589_4 Glycosyl transferase family 2 - - - 0.00001196 50.0
TH2_k127_5669215_0 Catalyzes the conversion of chorismate to isochorismate K02552 - 5.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003403 283.0
TH2_k127_5675053_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 414.0
TH2_k127_5675053_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005998 270.0
TH2_k127_5675053_2 DJ-1/PfpI family K03152,K05520,K05687,K12132 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009100,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019538,GO:0022613,GO:0030091,GO:0033554,GO:0034599,GO:0036211,GO:0036524,GO:0036525,GO:0042026,GO:0042221,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 2.7.11.1,3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000001532 237.0
TH2_k127_5675053_3 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000005583 211.0
TH2_k127_5675053_4 Protein of unknown function (DUF2905) - - - 0.00000000008097 65.0
TH2_k127_5687754_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 535.0
TH2_k127_5687754_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 421.0
TH2_k127_5687754_2 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 367.0
TH2_k127_5687754_3 Electron transfer flavoprotein K03521,K22431 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000445 196.0
TH2_k127_5692644_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 598.0
TH2_k127_5692644_1 Phosphoglycerate kinase K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 465.0
TH2_k127_5692644_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009836 314.0
TH2_k127_5692644_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000003706 215.0
TH2_k127_5692644_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000005803 181.0
TH2_k127_5692644_5 PFAM Thioredoxin K03671 - - 0.0000000000000000000000000000000000007996 145.0
TH2_k127_5692644_6 Ankyrin repeat and SOCS K10324,K10325 GO:0000151,GO:0000209,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0007154,GO:0007165,GO:0007275,GO:0007517,GO:0007519,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009888,GO:0009987,GO:0014706,GO:0016567,GO:0019538,GO:0019941,GO:0023052,GO:0030154,GO:0030163,GO:0031461,GO:0031466,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0035914,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045445,GO:0048513,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051603,GO:0051716,GO:0060537,GO:0060538,GO:0061061,GO:0065007,GO:0070647,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234 - 0.0004874 46.0
TH2_k127_5694981_0 TIGRFAM competence protein ComEA helix-hairpin-helix repeat region K06959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 553.0
TH2_k127_5694981_1 ATPase activity K06027 - 3.6.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 510.0
TH2_k127_5694981_3 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000964 176.0
TH2_k127_5695167_0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003872 263.0
TH2_k127_5695167_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001681 250.0
TH2_k127_5695167_2 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005313 246.0
TH2_k127_5695167_3 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000000003929 198.0
TH2_k127_5695167_4 TIGRFAM flagellar biosynthetic protein FliS K02422 - - 0.000000000000000000000000001787 115.0
TH2_k127_5695167_5 PFAM flagellar protein FliS K02422 - - 0.0000000000000000000001015 102.0
TH2_k127_5695167_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000002388 77.0
TH2_k127_5700450_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 7.358e-274 871.0
TH2_k127_5700450_1 glycosyl transferase - - - 0.00000000000000000000000000000000000001278 160.0
TH2_k127_5707169_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0 1052.0
TH2_k127_5707169_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 614.0
TH2_k127_5707169_10 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000002876 167.0
TH2_k127_5707169_11 TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000002173 171.0
TH2_k127_5707169_12 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000001113 143.0
TH2_k127_5707169_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000003312 121.0
TH2_k127_5707169_2 neurotransmitter:sodium symporter activity K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 511.0
TH2_k127_5707169_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007777 461.0
TH2_k127_5707169_4 aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 397.0
TH2_k127_5707169_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004803 259.0
TH2_k127_5707169_6 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000001098 232.0
TH2_k127_5707169_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001959 239.0
TH2_k127_5707169_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000002952 237.0
TH2_k127_5707169_9 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000001536 201.0
TH2_k127_5707486_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 465.0
TH2_k127_5707486_1 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 299.0
TH2_k127_5707486_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000000000000000000000000000000000000000000883 160.0
TH2_k127_5707486_3 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.000000000000000000000000000000000000000001067 162.0
TH2_k127_5707486_4 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.0000000000000000000000000000000000000001827 154.0
TH2_k127_5707486_5 late embryogenesis abundant protein - - - 0.0000000000000000000001592 102.0
TH2_k127_5707486_6 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0001178 46.0
TH2_k127_5713173_0 Beta-xylosidase K22268 - 3.2.1.37 1.613e-271 852.0
TH2_k127_5713173_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 509.0
TH2_k127_5713173_10 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000005784 241.0
TH2_k127_5713173_11 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000004057 223.0
TH2_k127_5713173_12 PFAM Rhomboid family - - - 0.0000000000000000000000000000000006312 145.0
TH2_k127_5713173_13 Streptomycin adenylyltransferase - - - 0.00000000000000000000146 104.0
TH2_k127_5713173_14 - - - - 0.0000000000008583 78.0
TH2_k127_5713173_15 - - - - 0.000000000002723 79.0
TH2_k127_5713173_16 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000004585 78.0
TH2_k127_5713173_17 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000436 52.0
TH2_k127_5713173_2 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 462.0
TH2_k127_5713173_3 Ig domain protein group 2 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 394.0
TH2_k127_5713173_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 352.0
TH2_k127_5713173_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 349.0
TH2_k127_5713173_6 Ig domain protein group 2 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 337.0
TH2_k127_5713173_7 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 295.0
TH2_k127_5713173_8 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001241 268.0
TH2_k127_5713173_9 3-demethylubiquinone-9 3-O-methyltransferase activity K06219 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004185 258.0
TH2_k127_5717037_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 488.0
TH2_k127_5717037_1 Glycosyl hydrolases family 2 K01192 - 3.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 398.0
TH2_k127_5717037_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000004571 136.0
TH2_k127_5721118_0 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 407.0
TH2_k127_5721118_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 290.0
TH2_k127_5721118_2 stress-induced protein - - - 0.00000000000000000000000000000000000000000000000000002358 199.0
TH2_k127_5721118_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000003942 190.0
TH2_k127_5721118_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000001088 119.0
TH2_k127_5721118_5 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000005512 71.0
TH2_k127_5721118_6 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000002489 58.0
TH2_k127_5724795_0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 373.0
TH2_k127_5724795_1 NAD binding K03778 - 1.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 331.0
TH2_k127_5724795_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000007817 214.0
TH2_k127_5724795_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000001468 68.0
TH2_k127_5757478_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 308.0
TH2_k127_5757478_1 Belongs to the SEDS family K03588 - - 0.000000000000002524 83.0
TH2_k127_5820821_0 Utp--glucose-1-phosphate uridylyltransferase K00972,K11442 - 2.7.7.23,2.7.7.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 466.0
TH2_k127_5820821_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 314.0
TH2_k127_5820821_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000001357 94.0
TH2_k127_5822582_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 593.0
TH2_k127_5822582_1 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 491.0
TH2_k127_5822582_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 351.0
TH2_k127_5840148_0 Domain of unknown function (DUF2088) - - - 7.619e-201 633.0
TH2_k127_5840148_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 456.0
TH2_k127_5840148_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 314.0
TH2_k127_5840148_3 ROK family - - - 0.00000007626 59.0
TH2_k127_5840541_0 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 344.0
TH2_k127_5840541_1 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000001347 186.0
TH2_k127_5840541_2 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000001103 157.0
TH2_k127_5840541_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000117 137.0
TH2_k127_5840541_4 Alternative locus ID K06995 - - 0.00000000000000000000004374 102.0
TH2_k127_5855232_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 393.0
TH2_k127_5855232_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006303 273.0
TH2_k127_5855232_3 Secondary thiamine-phosphate synthase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000004324 230.0
TH2_k127_5855232_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000001897 92.0
TH2_k127_5866248_0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain K13747 - 4.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 485.0
TH2_k127_5866248_1 Bax inhibitor 1 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007431 241.0
TH2_k127_5866248_2 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000004853 227.0
TH2_k127_5879191_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000001359 222.0
TH2_k127_5879191_1 Ribonuclease H K03469 - 3.1.26.4 0.00000000000000000000000000000001873 139.0
TH2_k127_5879191_2 - K07164,K22391 - 3.5.4.16 0.000000000000000000002689 104.0
TH2_k127_5879191_3 PFAM PEGA domain - - - 0.0000000000000000007832 91.0
TH2_k127_5879191_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00004577 51.0
TH2_k127_5886657_0 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 274.0
TH2_k127_5886657_1 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000007539 168.0
TH2_k127_5886657_2 with chaperone activity ATP-binding K03696 - - 0.0000000000000000000000000000000000002613 146.0
TH2_k127_5886657_3 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000001143 139.0
TH2_k127_5886657_4 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000002458 109.0
TH2_k127_5902633_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 2.796e-315 987.0
TH2_k127_5902633_1 Domain of unknown function (DUF4954) - - - 1.707e-262 827.0
TH2_k127_5902633_10 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.000000000000000000000000000000002501 134.0
TH2_k127_5902633_11 PFAM Phosphoribosyltransferase K02242 - - 0.000000000000000000000007433 106.0
TH2_k127_5902633_12 4Fe-4S binding domain - - - 0.000000000000000002733 85.0
TH2_k127_5902633_13 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000002348 72.0
TH2_k127_5902633_15 - - - - 0.00002191 47.0
TH2_k127_5902633_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 6.973e-234 729.0
TH2_k127_5902633_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 486.0
TH2_k127_5902633_4 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 348.0
TH2_k127_5902633_5 sugar isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 331.0
TH2_k127_5902633_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001832 254.0
TH2_k127_5902633_7 FMN binding K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000004611 168.0
TH2_k127_5902633_8 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.000000000000000000000000000000000000002412 151.0
TH2_k127_5902633_9 Hydrolase - - - 0.000000000000000000000000000000002177 139.0
TH2_k127_5936672_0 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 520.0
TH2_k127_5936672_1 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 425.0
TH2_k127_5936672_2 TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 389.0
TH2_k127_5936672_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000002089 184.0
TH2_k127_5954822_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.808e-201 640.0
TH2_k127_5954822_1 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002379 245.0
TH2_k127_5954822_2 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000003582 220.0
TH2_k127_5954822_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000002445 190.0
TH2_k127_5954822_4 Histidine kinase - - - 0.00000000000000000000000000000000000434 147.0
TH2_k127_5954822_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000008173 126.0
TH2_k127_5954822_6 COG1253 Hemolysins and related - - - 0.0000000000000000000000005139 117.0
TH2_k127_5965607_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 4.308e-287 901.0
TH2_k127_5965607_1 elongation factor G K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 604.0
TH2_k127_5965607_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 430.0
TH2_k127_6037672_0 hydrogenase large subunit K05922,K06281 - 1.12.5.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 503.0
TH2_k127_6037672_1 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 342.0
TH2_k127_6037672_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
TH2_k127_6037672_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000002277 195.0
TH2_k127_6037672_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000009745 185.0
TH2_k127_6037672_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000001201 179.0
TH2_k127_6037672_6 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000001359 138.0
TH2_k127_6049223_0 Glycosyl hydrolase family 63 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 615.0
TH2_k127_6049511_0 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 587.0
TH2_k127_6049511_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 501.0
TH2_k127_6049511_2 Rubrerythrin - - - 0.000000000000004429 81.0
TH2_k127_6063519_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1643.0
TH2_k127_6063519_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 2.091e-250 777.0
TH2_k127_6063519_2 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 599.0
TH2_k127_6063519_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004619 259.0
TH2_k127_6063519_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000007659 203.0
TH2_k127_6063519_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000001111 206.0
TH2_k127_6063519_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000009248 160.0
TH2_k127_6063519_7 ribosomal protein l10 K02864 - - 0.00000000000000001333 89.0
TH2_k127_6063519_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000004861 68.0
TH2_k127_6063519_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000002536 60.0
TH2_k127_6104367_0 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.0000000000000000000000000000000000000000000000000000166 202.0
TH2_k127_6104367_1 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000004019 178.0
TH2_k127_6104367_2 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000007831 160.0
TH2_k127_6104367_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179,K13276 - 3.2.1.4 0.000000000000000006659 98.0
TH2_k127_6104367_4 FAD linked oxidases, C-terminal domain - - - 0.0000000000001219 72.0
TH2_k127_6190013_0 aspartate kinase, monofunctional class K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 442.0
TH2_k127_6190013_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 0.00000000000000000000000000000000000000000000000000008246 196.0
TH2_k127_6190013_2 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000001202 145.0
TH2_k127_6190013_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 0.000000000000000000000001216 110.0
TH2_k127_6190013_4 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000000000000000004376 110.0
TH2_k127_6190013_5 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 0.00000000000000000000001748 112.0
TH2_k127_6190013_6 Tetratricopeptide repeat - - - 0.00000000001281 76.0
TH2_k127_6217946_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 6.935e-277 867.0
TH2_k127_6217946_1 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 5.128e-209 659.0
TH2_k127_6217946_2 helix_turn _helix lactose operon repressor K02529,K03435 - - 0.0000000000000000000003352 109.0
TH2_k127_6217946_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000003129 65.0
TH2_k127_6217946_4 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00002788 56.0
TH2_k127_6371863_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 2.074e-207 653.0
TH2_k127_6396871_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 401.0
TH2_k127_6396871_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000002909 234.0
TH2_k127_6396871_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000001054 218.0
TH2_k127_6452182_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008247 438.0
TH2_k127_6452182_1 PFAM peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 428.0
TH2_k127_6452182_10 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000001779 117.0
TH2_k127_6452182_11 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000632 107.0
TH2_k127_6452182_12 YacP-like NYN domain K06962 - - 0.0000006891 57.0
TH2_k127_6452182_13 Carbohydrate-selective porin, OprB family K07267 - - 0.00001516 49.0
TH2_k127_6452182_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 386.0
TH2_k127_6452182_3 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001221 286.0
TH2_k127_6452182_4 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000006254 250.0
TH2_k127_6452182_5 DHH family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001252 252.0
TH2_k127_6452182_6 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000000000000000000000000000000000000000003759 229.0
TH2_k127_6452182_7 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.00000000000000000000000000000000000000000000000000000000005688 212.0
TH2_k127_6452182_8 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000009747 165.0
TH2_k127_6452182_9 Cobalt transport protein K02008 - - 0.000000000000000000000000000000001227 139.0
TH2_k127_6689166_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 353.0
TH2_k127_6689166_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000462 249.0
TH2_k127_6689166_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000613 223.0
TH2_k127_6689166_3 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000005881 81.0
TH2_k127_6717879_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 416.0
TH2_k127_6717879_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 313.0
TH2_k127_6717879_10 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.00001661 47.0
TH2_k127_6717879_2 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000006913 201.0
TH2_k127_6717879_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000006663 189.0
TH2_k127_6717879_4 Belongs to the GSP D family K02453 - - 0.000000000000000000000000000000000000000000000002765 199.0
TH2_k127_6717879_5 Universal bacterial protein YeaZ K14742 - - 0.00000000000000000000000000449 120.0
TH2_k127_6717879_6 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.00000000000000000000002645 111.0
TH2_k127_6717879_7 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX K17759 - 5.1.99.6 0.0000000000000000000001896 100.0
TH2_k127_6717879_8 Protein involved in outer membrane biogenesis - - - 0.00000000000000000006523 100.0
TH2_k127_6717879_9 DUF167 K09131 - - 0.0000000000000001246 83.0
TH2_k127_6722661_0 hydrogenase large subunit K00533,K06281 - 1.12.7.2,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 542.0
TH2_k127_6722661_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 467.0
TH2_k127_6722661_10 PFAM chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000001414 217.0
TH2_k127_6722661_11 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000005505 143.0
TH2_k127_6722661_2 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 370.0
TH2_k127_6722661_3 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 314.0
TH2_k127_6722661_4 Hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 309.0
TH2_k127_6722661_5 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 299.0
TH2_k127_6722661_6 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007901 288.0
TH2_k127_6722661_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000003959 271.0
TH2_k127_6722661_8 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001467 266.0
TH2_k127_6722661_9 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001193 269.0
TH2_k127_6753059_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 554.0
TH2_k127_6753059_1 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 334.0
TH2_k127_6753059_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 304.0
TH2_k127_6753059_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000008107 237.0
TH2_k127_6753059_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000007342 224.0
TH2_k127_6753059_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000005099 196.0
TH2_k127_6753059_6 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT K02669 - - 0.00000000000000000000000002805 109.0
TH2_k127_6753059_7 Putative regulatory protein - - - 0.0000000197 57.0
TH2_k127_6761305_0 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007404 266.0
TH2_k127_6761305_1 Formate nitrite family of K21993 - - 0.00000000000000000000000000000000000000000000000000000004498 206.0
TH2_k127_6761305_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000004817 145.0
TH2_k127_6761305_3 Ribonuclease B OB domain - - - 0.000000000000000000000000000001081 122.0
TH2_k127_6783983_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.492e-223 703.0
TH2_k127_6783983_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 3.244e-195 619.0
TH2_k127_6783983_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000005344 251.0
TH2_k127_6783983_3 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000002628 171.0
TH2_k127_6783983_4 Nucleotidyltransferase domain - - - 0.00000000000000002124 85.0
TH2_k127_6783983_5 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000001322 80.0
TH2_k127_6783983_6 HEPN domain - - - 0.00000000000003396 79.0
TH2_k127_6797969_0 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 407.0
TH2_k127_6797969_1 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000002748 246.0
TH2_k127_6797969_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000001182 235.0
TH2_k127_6852573_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1175.0
TH2_k127_6852573_1 Listeria-Bacteroides repeat domain (List_Bact_rpt) - - - 0.0000226 53.0
TH2_k127_6889095_0 PFAM Glycosyl transferase family 2 K00752,K11936 - 2.4.1.212 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 426.0
TH2_k127_6889095_1 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 367.0
TH2_k127_6889095_2 abc transporter atp-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000003494 243.0
TH2_k127_6889095_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000009856 215.0
TH2_k127_6889095_4 exonuclease K07462 - - 0.0000001749 55.0
TH2_k127_6889095_5 Major Facilitator Superfamily - - - 0.000002312 59.0
TH2_k127_6889095_6 histidinol phosphate phosphatase K04486 - 3.1.3.15 0.00001384 55.0
TH2_k127_6898289_0 Raffinose synthase or seed imbibition protein Sip1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 497.0
TH2_k127_6898289_1 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006277 274.0
TH2_k127_6898289_2 Transposase domain (DUF772) - - - 0.00000000000000000000000000000000000000004416 156.0
TH2_k127_6898289_3 Endoglucanase K01218 - 3.2.1.78 0.00000000000000000000000000000000000233 160.0
TH2_k127_6898289_4 Carbohydrate binding domain - - - 0.0000002981 59.0
TH2_k127_6915238_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K10754 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 552.0
TH2_k127_6915238_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 392.0
TH2_k127_6915238_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000002268 204.0
TH2_k127_6915238_3 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000000000009854 158.0
TH2_k127_6915238_4 Phospholipase/Carboxylesterase - - - 0.0000003932 61.0
TH2_k127_6918847_0 Required for chromosome condensation and partitioning K03529 - - 3.568e-194 649.0
TH2_k127_6918847_1 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 378.0
TH2_k127_6918847_2 PFAM Peptidase M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005861 291.0
TH2_k127_6918847_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation - - - 0.0000000000004371 81.0
TH2_k127_6970118_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.334e-217 683.0
TH2_k127_6970118_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 451.0
TH2_k127_6970118_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000209 168.0
TH2_k127_6975141_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000003712 213.0
TH2_k127_6975141_1 HEPN domain - - - 0.00000000000000000000000000000009554 127.0
TH2_k127_6975141_2 cheY-homologous receiver domain K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000000000000135 110.0
TH2_k127_7009436_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 424.0
TH2_k127_7009436_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 415.0
TH2_k127_7009436_3 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004043 279.0
TH2_k127_7009436_4 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000009941 209.0
TH2_k127_7009436_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000006914 177.0
TH2_k127_7009436_6 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000002546 169.0
TH2_k127_7009436_7 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000447 157.0
TH2_k127_7009436_8 COG1716 FOG FHA domain - - - 0.000000000000006515 82.0
TH2_k127_7009436_9 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0007219 50.0
TH2_k127_7035100_0 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000005537 192.0
TH2_k127_7041081_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 2.306e-242 765.0
TH2_k127_7041081_1 endonuclease III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001656 265.0
TH2_k127_7041081_2 TIGRFAM mannose-6-phosphate isomerase, class I K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000002016 262.0
TH2_k127_7041081_3 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000007326 126.0
TH2_k127_7041081_4 CAAX protease self-immunity - - - 0.000000000000000000000000001394 124.0
TH2_k127_7041081_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.000000000000000000000001603 110.0
TH2_k127_7041081_6 Protein of unknown function DUF2617 - - - 0.000000000000000000009749 98.0
TH2_k127_7059397_0 Domain of unknown function (DUF5110) K01811 - 3.2.1.177 5.141e-219 701.0
TH2_k127_7059397_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000009497 245.0
TH2_k127_7059397_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000000000000002635 109.0
TH2_k127_7083899_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 428.0
TH2_k127_7083899_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000009995 256.0
TH2_k127_7083899_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000007822 252.0
TH2_k127_7083899_3 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000172 237.0
TH2_k127_7083899_4 GGDEF domain - - - 0.00000000000001229 85.0
TH2_k127_7091017_0 Hypothetical glycosyl hydrolase 6 - - - 9.852e-264 828.0
TH2_k127_7091017_1 DeoC/LacD family aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 560.0
TH2_k127_7091017_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 526.0
TH2_k127_7091017_3 Major facilitator Superfamily K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 312.0
TH2_k127_7091017_4 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000004649 223.0
TH2_k127_7091017_5 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000004802 219.0
TH2_k127_7091017_6 Sigma-70, region 4 - - - 0.0000000000000000000000000000000005555 138.0
TH2_k127_7123726_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 5.672e-218 684.0
TH2_k127_7123726_1 Trp repressor protein K03720 - - 0.00000000000000002673 85.0
TH2_k127_7123726_2 PFAM Sulfate transporter antisigma-factor antagonist STAS K06378 - - 0.0000906 49.0
TH2_k127_7123726_3 - - - - 0.0001268 44.0
TH2_k127_7141870_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 541.0
TH2_k127_7141870_1 aminotransferase class I and II K14261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 504.0
TH2_k127_7141870_2 Cation transport protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 327.0
TH2_k127_7141870_3 TrkA-C domain K03499 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000001577 181.0
TH2_k127_7144341_0 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 340.0
TH2_k127_7144341_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003551 279.0
TH2_k127_7144341_2 Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000001156 243.0
TH2_k127_7144341_3 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000004474 166.0
TH2_k127_7144341_4 Transposase - - - 0.0000205 50.0
TH2_k127_7144341_5 DDE superfamily endonuclease - - - 0.0005671 49.0
TH2_k127_7173993_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 520.0
TH2_k127_7173993_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 466.0
TH2_k127_7173993_2 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000005053 239.0
TH2_k127_7173993_3 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.000000000000000000000000000006051 123.0
TH2_k127_7173993_4 belongs to the carbohydrate kinase PfkB family - - - 0.000000000000000000000000001989 124.0
TH2_k127_7206756_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 590.0
TH2_k127_7206756_1 pyruvate kinase activity K00873,K00958 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 342.0
TH2_k127_7206756_2 Belongs to the LDH MDH superfamily K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000009893 78.0
TH2_k127_7250141_0 tRNA synthetases class II (D, K and N) K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 335.0
TH2_k127_7250141_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000007509 220.0
TH2_k127_7263155_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.00000000000000000000000000000000000000000000000000000000003812 211.0
TH2_k127_7263155_1 Hemerythrin HHE cation binding domain K09155 - - 0.00000000000000000000000000000008204 134.0
TH2_k127_7263155_2 AraC-like ligand binding domain - - - 0.000000000000000000000000000004251 122.0
TH2_k127_7263155_3 Transcriptional regulator, BadM Rrf2 family - - - 0.00000000000000000000000000002969 122.0
TH2_k127_7263155_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000001048 124.0
TH2_k127_7263155_5 TM2 domain - - - 0.0002478 46.0
TH2_k127_7318120_0 Isocitrate isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 546.0
TH2_k127_7318120_1 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 518.0
TH2_k127_7318120_10 PFAM Glycosyl transferase, group 1 K02844 - - 0.000000000000000000000000000000000001534 153.0
TH2_k127_7318120_11 Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core K02848 - - 0.00000000000000005106 91.0
TH2_k127_7318120_2 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 463.0
TH2_k127_7318120_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 428.0
TH2_k127_7318120_4 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 407.0
TH2_k127_7318120_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 337.0
TH2_k127_7318120_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000001424 248.0
TH2_k127_7318120_7 COG0859 ADP-heptose LPS heptosyltransferase K02843 - - 0.0000000000000000000000000000000000000000000000000000000000003064 224.0
TH2_k127_7318120_8 D,D-heptose 1,7-bisphosphate phosphatase - - - 0.000000000000000000000000000000000000000000002861 177.0
TH2_k127_7318120_9 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000001324 166.0
TH2_k127_7343424_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005892 263.0
TH2_k127_7343424_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000579 218.0
TH2_k127_7348898_0 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 355.0
TH2_k127_7348898_1 transferase K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000001391 209.0
TH2_k127_7348898_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000008135 139.0
TH2_k127_7348898_4 Protein of unknown function (DUF2997) - - - 0.000000000005273 68.0
TH2_k127_7348898_5 Signal peptidase, peptidase S26 - - - 0.00002165 56.0
TH2_k127_7382235_0 Sugar-binding cellulase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 354.0
TH2_k127_7382235_1 - - - - 0.000000000000000000000000000001295 140.0
TH2_k127_7466412_0 SMART Elongator protein 3 MiaB NifB - - - 8.84e-211 666.0
TH2_k127_7466412_1 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000007003 117.0
TH2_k127_7466412_2 cell redox homeostasis K02199 - - 0.000000000000000000000000374 110.0
TH2_k127_7466412_3 Biopolymer transport protein ExbD/TolR K03559 - - 0.00002531 53.0
TH2_k127_7504738_0 Heat shock 70 kDa protein K04043 - - 1.397e-273 854.0
TH2_k127_7504738_1 PFAM Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 346.0
TH2_k127_7504738_2 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain - - - 0.00000000000000000000000001222 110.0
TH2_k127_768874_0 chitin binding K01183 - 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 342.0
TH2_k127_768874_1 Dehydratase family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000004694 150.0
TH2_k127_768874_2 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000004777 144.0
TH2_k127_768874_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000593 134.0
TH2_k127_768874_4 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000001964 122.0
TH2_k127_7822935_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 516.0
TH2_k127_7822935_1 TIGRFAM ribonuclease, Rne Rng family K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 483.0
TH2_k127_7822935_10 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.000000000009457 70.0
TH2_k127_7822935_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 289.0
TH2_k127_7822935_3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000004367 169.0
TH2_k127_7822935_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000101 158.0
TH2_k127_7822935_5 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02768,K02806 - 2.7.1.202 0.00000000000000000000000000000002335 131.0
TH2_k127_7822935_6 PFAM MgtC SapB transporter K07507 - - 0.000000000000000000000000000008539 124.0
TH2_k127_7822935_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000001004 104.0
TH2_k127_7822935_8 protein conserved in bacteria (DUF2344) - - - 0.000000000001515 76.0
TH2_k127_7822935_9 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.000000000004643 70.0
TH2_k127_7834623_0 membrane GTPase involved in stress response K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 491.0
TH2_k127_7834623_1 rna polymerase sigma-54 factor K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 349.0
TH2_k127_7834623_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 351.0
TH2_k127_7834623_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000003753 239.0
TH2_k127_7834623_4 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000001853 124.0
TH2_k127_7834623_5 N-acetylmuramoyl-L-alanine amidase - - - 0.000000002796 64.0
TH2_k127_7834623_6 COG NOG33517 non supervised orthologous group - - - 0.000003059 53.0
TH2_k127_7841068_0 AcrB/AcrD/AcrF family K03296,K19594 - - 0.0 1111.0
TH2_k127_7841068_1 PQQ-like domain K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 410.0
TH2_k127_7841068_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.00000000000000000000000000000000000000000000000000000000006898 222.0
TH2_k127_7841068_11 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000007536 191.0
TH2_k127_7841068_12 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000003601 188.0
TH2_k127_7841068_13 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000202 162.0
TH2_k127_7841068_14 PFAM Copper amine oxidase N-terminal domain K01448 - 3.5.1.28 0.00000000000000000000000000000002214 138.0
TH2_k127_7841068_15 Belongs to the bacterial histone-like protein family K03530,K05788 - - 0.00000000000000000000000000002262 120.0
TH2_k127_7841068_16 zinc ion binding K06204 - - 0.0000000000000000000000176 108.0
TH2_k127_7841068_17 Cold shock protein K03704 - - 0.000000000000000004143 85.0
TH2_k127_7841068_18 SpoIIAA-like - - - 0.000000000000001567 81.0
TH2_k127_7841068_2 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 408.0
TH2_k127_7841068_3 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 353.0
TH2_k127_7841068_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 323.0
TH2_k127_7841068_5 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 308.0
TH2_k127_7841068_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K19595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 300.0
TH2_k127_7841068_7 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 290.0
TH2_k127_7841068_8 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000001365 246.0
TH2_k127_7841068_9 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000001931 214.0
TH2_k127_7841402_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 525.0
TH2_k127_7841402_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 504.0
TH2_k127_7841402_10 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000001467 218.0
TH2_k127_7841402_11 PFAM Desulfoferrodoxin ferrous iron-binding region K05919 - 1.15.1.2 0.000000000000000000000000000000000000000000000000000000000004068 210.0
TH2_k127_7841402_12 Protein of unknown function (DUF2959) - - - 0.0000000000000000000000000000000000000000000000000000001711 201.0
TH2_k127_7841402_13 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000002686 194.0
TH2_k127_7841402_14 Belongs to the Fur family K09825 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000374,GO:2001141 - 0.0000000000000000000000000000000000000000009378 161.0
TH2_k127_7841402_15 Rubrerythrin - - - 0.00000000000000000000000000000000005659 139.0
TH2_k127_7841402_16 - - - - 0.000000000000000000000000000004133 124.0
TH2_k127_7841402_17 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000001298 100.0
TH2_k127_7841402_18 FMN_bind K00348 - 1.6.5.8 0.000000000000000000006562 101.0
TH2_k127_7841402_19 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000005072 95.0
TH2_k127_7841402_2 ATPase (AAA superfamily K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 418.0
TH2_k127_7841402_20 Permease YjgP YjgQ family K07091 - - 0.0000000000002123 83.0
TH2_k127_7841402_21 Transposase K07491 - - 0.0000002114 52.0
TH2_k127_7841402_22 Lysin motif - - - 0.00000122 61.0
TH2_k127_7841402_23 Permease, YjgP YjgQ family K11720 - - 0.000003334 59.0
TH2_k127_7841402_3 sodium ion transport K00351,K16161,K16246,K18225 GO:0003674,GO:0003824,GO:0004497,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0018662,GO:0018958,GO:0018959,GO:0019336,GO:0019439,GO:0044237,GO:0044248,GO:0046191,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 1.14.13.25,1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 375.0
TH2_k127_7841402_4 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 348.0
TH2_k127_7841402_5 Ferritin-like domain - GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006283 267.0
TH2_k127_7841402_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000009233 259.0
TH2_k127_7841402_7 Rnf-Nqr subunit, membrane protein K00350 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000001649 242.0
TH2_k127_7841402_8 Belongs to the NqrDE RnfAE family K00349 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000013 230.0
TH2_k127_7841402_9 NQR2, RnfD, RnfE family K00347 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000006735 232.0
TH2_k127_7848992_0 PFAM D12 class N6 adenine-specific DNA methyltransferase K07318 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 521.0
TH2_k127_7848992_1 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004161 270.0
TH2_k127_7848992_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000002395 164.0
TH2_k127_7848992_3 ABC transporter - - - 0.000000000000000000000000000000000000005326 149.0
TH2_k127_7863854_0 L-rhamnose isomerase activity K00848,K01813 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008270,GO:0008740,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0022607,GO:0030145,GO:0030246,GO:0032991,GO:0033296,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046872,GO:0046914,GO:0048029,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901575 2.7.1.5,5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 593.0
TH2_k127_7863854_1 Alcohol dehydrogenase GroES-like domain K19956 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 499.0
TH2_k127_7863854_2 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 489.0
TH2_k127_7863854_3 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 378.0
TH2_k127_7863854_4 PFAM Short-chain dehydrogenase reductase SDR K00068 - 1.1.1.140 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 356.0
TH2_k127_7863854_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001142 281.0
TH2_k127_7863854_6 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000278 231.0
TH2_k127_7863854_7 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000008349 178.0
TH2_k127_7863854_8 L-fucose isomerase, first N-terminal domain K01818 - 5.3.1.25,5.3.1.3 0.000000000000000000000000000002578 122.0
TH2_k127_7869231_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 478.0
TH2_k127_7869231_1 PFAM Metal-dependent phosphohydrolase, HD K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 326.0
TH2_k127_7869231_2 Phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 316.0
TH2_k127_7869231_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000006983 254.0
TH2_k127_7869231_4 COG1253 Hemolysins and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000491 256.0
TH2_k127_7869231_5 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000002801 134.0
TH2_k127_7869231_6 - - - - 0.000000000000000000000000002479 113.0
TH2_k127_7869231_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000004003 114.0
TH2_k127_7869231_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000005562 78.0
TH2_k127_7884179_0 PFAM ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 382.0
TH2_k127_7884179_1 zinc-ribbon domain - - - 0.0000000000000001071 85.0
TH2_k127_7884179_2 Transcription factor zinc-finger - - - 0.00000000009759 68.0
TH2_k127_7893081_0 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 514.0
TH2_k127_7893081_1 - - - - 0.0000000000000000000000000000000000000000000000003713 186.0
TH2_k127_7913815_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 392.0
TH2_k127_7913815_1 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004071 289.0
TH2_k127_7913815_2 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.00000000000000000000000000000000001517 141.0
TH2_k127_7913815_3 C subunit K02119 - - 0.0000000000000000000000000000000009135 143.0
TH2_k127_7913815_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000003503 106.0
TH2_k127_7913815_5 PFAM Vacuolar H transporting two-sector ATPase F subunit K02122 - - 0.0004646 47.0
TH2_k127_7913825_0 formate C-acetyltransferase glycine radical K00656,K20038 - 2.3.1.54,4.3.99.4 1.523e-259 808.0
TH2_k127_7913825_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 281.0
TH2_k127_7913825_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002151 262.0
TH2_k127_7913825_3 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000003692 254.0
TH2_k127_7913825_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000004881 221.0
TH2_k127_7913825_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000002192 179.0
TH2_k127_7913825_6 AsmA-like C-terminal region K07289 - - 0.00000000000000002595 97.0
TH2_k127_7913825_7 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000149 72.0
TH2_k127_7944759_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381 - 1.2.4.1,1.2.4.4 7.046e-301 934.0
TH2_k127_7944759_1 DeoR C terminal sensor domain - - - 0.0000000000000000000000000000000000004401 150.0
TH2_k127_7944759_2 Alpha/beta hydrolase family - - - 0.000000000009607 72.0
TH2_k127_7944759_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000004458 64.0
TH2_k127_7967527_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 378.0
TH2_k127_7967527_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001949 282.0
TH2_k127_7967527_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000000000000004813 163.0
TH2_k127_7967527_3 Protein of unknown function (DUF4056) - - - 0.0000000000000000000002353 109.0
TH2_k127_7967527_4 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000006757 65.0
TH2_k127_7982462_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 320.0
TH2_k127_7982462_1 - - - - 0.00000000000000000000000004576 124.0
TH2_k127_7999334_0 Polysaccharide biosynthesis protein CapD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 559.0
TH2_k127_7999334_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 518.0
TH2_k127_7999334_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 337.0
TH2_k127_7999334_3 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007025 253.0
TH2_k127_7999334_4 Belongs to the RbsD FucU family K02431 - 5.1.3.29 0.000000000000000000000000000000000000000000000000000000002708 202.0
TH2_k127_7999334_5 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000001106 112.0
TH2_k127_7999334_6 - - - - 0.000000000008705 73.0
TH2_k127_7999334_8 - - - - 0.00000003547 66.0
TH2_k127_8016272_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 364.0
TH2_k127_8016272_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000004217 171.0
TH2_k127_8016272_2 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000704 164.0
TH2_k127_8016272_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000002795 134.0
TH2_k127_8016272_4 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00002557 46.0
TH2_k127_8051051_0 Oxidoreductase NAD-binding domain K00528,K02823,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 310.0
TH2_k127_8051051_1 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000006453 267.0
TH2_k127_8051051_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000005035 182.0
TH2_k127_8051051_3 hydrogenase expression formation protein K03605 - - 0.00000000000000000000000001552 114.0
TH2_k127_8064346_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.438e-216 687.0
TH2_k127_8064346_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 345.0
TH2_k127_8064346_2 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.000000000000000000000000000000000000000000000000000009748 210.0
TH2_k127_8064346_3 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000008141 134.0
TH2_k127_8064346_4 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000502 130.0
TH2_k127_8064346_5 - K01992 - - 0.0000000009967 69.0
TH2_k127_8064346_6 Helix-turn-helix domain - - - 0.00007066 46.0
TH2_k127_8066166_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 533.0
TH2_k127_8066166_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 455.0
TH2_k127_8066166_2 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 411.0
TH2_k127_8066166_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000007892 173.0
TH2_k127_8066166_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000216 133.0
TH2_k127_8066166_5 RNase_H superfamily K07502 - - 0.00000000000000000006547 90.0
TH2_k127_8203560_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 603.0
TH2_k127_8203560_1 Fructose-1,6-bisphosphate aldolase, class II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 422.0
TH2_k127_8203560_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 409.0
TH2_k127_8203560_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 371.0
TH2_k127_8203560_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000001054 248.0
TH2_k127_8203560_5 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000119 216.0
TH2_k127_8203560_6 - - - - 0.000488 48.0
TH2_k127_8207905_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 3.182e-267 838.0
TH2_k127_8207905_1 PFAM ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005751 249.0
TH2_k127_8207905_10 FeoA K04758 - - 0.0000000001064 64.0
TH2_k127_8207905_11 Staphylococcal nuclease homologue - - - 0.000000002694 66.0
TH2_k127_8207905_12 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016740,GO:0016782,GO:0016783,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000002306 63.0
TH2_k127_8207905_13 competence protein COMEC K02238 - - 0.00001179 55.0
TH2_k127_8207905_2 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000002261 244.0
TH2_k127_8207905_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000003673 195.0
TH2_k127_8207905_4 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000006892 146.0
TH2_k127_8207905_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000001131 153.0
TH2_k127_8207905_6 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02768 - 2.7.1.202 0.00000000000000000000000000000000001055 140.0
TH2_k127_8207905_7 cobalamin binding - - - 0.0000000000000000000000000000000004221 140.0
TH2_k127_8207905_8 - - - - 0.0000000000000000000000000000001024 129.0
TH2_k127_8207905_9 PFAM Iron dependent repressor, metal binding and dimerisation domain K03709 - - 0.000000000008341 68.0
TH2_k127_8234935_0 Vault protein inter-alpha-trypsin domain K07114 - - 1.292e-196 629.0
TH2_k127_8234935_1 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 336.0
TH2_k127_8234935_2 - - - - 0.0000001913 62.0
TH2_k127_8249962_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 8.059e-236 745.0
TH2_k127_8249962_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009382 261.0
TH2_k127_8265469_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 362.0
TH2_k127_8265469_1 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000199 222.0
TH2_k127_8265469_2 nucleotidyltransferase activity - - - 0.000000000000000000000000000000001324 134.0
TH2_k127_8265469_3 Transcriptional K07979 - - 0.0000000000000000000009711 100.0
TH2_k127_8265469_4 nucleotidyltransferase activity - - - 0.000000000000000000001925 96.0
TH2_k127_8265469_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000001071 61.0
TH2_k127_8265469_6 response regulator - - - 0.00002593 48.0
TH2_k127_8265469_7 ABC transporter permease K01992 - - 0.0003691 51.0
TH2_k127_8294603_0 protein conserved in bacteria K09859 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 316.0
TH2_k127_8294603_1 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337 - - 0.00000000000000000000000000000000000000000000000000000000000001552 221.0
TH2_k127_8294603_2 Helix-turn-helix domain - - - 0.000000001173 62.0
TH2_k127_8294603_4 Lipoprotein - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000008862 60.0
TH2_k127_8294603_5 curli production assembly transport component CsgG - - - 0.0008138 45.0
TH2_k127_8334440_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K04085 - - 7.063e-250 782.0
TH2_k127_8334440_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.492e-248 784.0
TH2_k127_8334440_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 486.0
TH2_k127_8334440_3 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 297.0
TH2_k127_8334440_4 signal peptidase-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000001064 233.0
TH2_k127_8334440_5 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000008232 175.0
TH2_k127_8334440_6 COG2812 DNA polymerase III, gamma tau subunits K02341 - 2.7.7.7 0.000000000000000000000000000007825 130.0
TH2_k127_8334440_7 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000003872 106.0
TH2_k127_8334440_8 - - - - 0.000000000000000000162 93.0
TH2_k127_8334440_9 Glycogen debranching enzyme - - - 0.0000000000003476 71.0
TH2_k127_83398_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 517.0
TH2_k127_83398_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006708 256.0
TH2_k127_83398_2 COG0147 Anthranilate para-aminobenzoate synthases component I K01657,K13503 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.00000000000000008945 91.0
TH2_k127_8340343_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 344.0
TH2_k127_8340343_1 Class II Aldolase and Adducin N-terminal domain K03077 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 299.0
TH2_k127_8340343_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008513 289.0
TH2_k127_8340343_3 Belongs to the 'phage' integrase family - - - 0.0000008828 58.0
TH2_k127_8340343_4 ribulokinase activity K00853 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008741,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046373,GO:0046835,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 2.7.1.16 0.000007525 49.0
TH2_k127_8340343_5 hydrolase K01048 - 3.1.1.5 0.0001273 45.0
TH2_k127_8446572_0 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 442.0
TH2_k127_8446572_1 Nucleotidyltransferase domain - - - 0.00000000000000001749 86.0
TH2_k127_8446572_2 HEPN domain - - - 0.000004639 51.0
TH2_k127_8464826_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.22e-254 791.0
TH2_k127_8464826_1 glucuronate isomerase K01812 - 5.3.1.12 8.317e-229 715.0
TH2_k127_8464826_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005562 273.0
TH2_k127_8464826_3 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000009862 169.0
TH2_k127_8475115_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.299e-244 782.0
TH2_k127_8475115_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 592.0
TH2_k127_8475115_10 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000001754 183.0
TH2_k127_8475115_11 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000004542 136.0
TH2_k127_8475115_12 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00003602 48.0
TH2_k127_8475115_2 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 498.0
TH2_k127_8475115_3 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 466.0
TH2_k127_8475115_4 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 310.0
TH2_k127_8475115_5 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004258 285.0
TH2_k127_8475115_6 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000007109 268.0
TH2_k127_8475115_7 AraC-like ligand binding domain K02854 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008894 262.0
TH2_k127_8475115_8 phosphoenolpyruvate-dependent sugar phosphotransferase system K05881 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000000000000000000007194 263.0
TH2_k127_8475115_9 Uncharacterized conserved protein (DUF2294) - - - 0.000000000000000000000000000000000000000000000000003951 183.0
TH2_k127_8512977_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 524.0
TH2_k127_8512977_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 332.0
TH2_k127_8512977_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006028 285.0
TH2_k127_8512977_3 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000001371 234.0
TH2_k127_8512977_4 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000001402 218.0
TH2_k127_8512977_5 PFAM regulatory protein, ArsR - - - 0.000000000000000000003927 96.0
TH2_k127_8512977_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K18930 - - 0.00006916 51.0
TH2_k127_8512977_7 general stress protein - - - 0.0002898 49.0
TH2_k127_8526146_0 Glycosyl hydrolase family 63 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 574.0
TH2_k127_8526146_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 424.0
TH2_k127_8526146_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 405.0
TH2_k127_8526146_3 - - - - 0.00000000000000000000000000000000000000000004579 177.0
TH2_k127_8526146_4 serine protease K07403 - - 0.00000000001886 76.0
TH2_k127_8526146_5 NfeD-like C-terminal, partner-binding K07403 - - 0.0001491 54.0
TH2_k127_85749_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 597.0
TH2_k127_85749_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 511.0
TH2_k127_85749_2 COG1674 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 465.0
TH2_k127_85749_3 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000001467 124.0
TH2_k127_85749_4 Periplasmic binding proteins and sugar binding domain of LacI family - - - 0.000000000000000007306 91.0
TH2_k127_8735939_0 Flagellar basal body rod protein K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000321 286.0
TH2_k127_8735939_1 Flagellar hook protein FlgE K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003087 286.0
TH2_k127_8735939_2 Flagellar basal body rod FlgEFG protein C-terminal - - - 0.00000000000000000000000000000000006971 143.0
TH2_k127_8735939_3 Chaperone for flagella basal body P-ring formation K02386 - - 0.0000000165 65.0
TH2_k127_87973_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 421.0
TH2_k127_87973_1 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 286.0
TH2_k127_87973_2 Hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000001132 209.0
TH2_k127_87973_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000003236 138.0
TH2_k127_87973_4 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000008116 97.0
TH2_k127_87973_5 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000421 95.0
TH2_k127_8797645_0 translation initiation factor activity K03496,K09000 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 295.0
TH2_k127_8797645_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001884 257.0
TH2_k127_8797645_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000001681 72.0
TH2_k127_8797645_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000001482 66.0
TH2_k127_8806557_0 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000002307 235.0
TH2_k127_8806557_1 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806,K04752 - 2.7.1.202 0.00000000000000000000008853 108.0
TH2_k127_8806557_2 Type II secretion system (T2SS), protein F K12278 - - 0.000000000000001695 81.0