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Overview

ID MAG03904
Name TH2_bin.30
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Myxococcota
Class Myxococcia
Order Myxococcales
Family Myxococcaceae
Genus
Species
Assembly information
Completeness (%) 69.54
Contamination (%) 1.07
GC content (%) 71.0
N50 (bp) 4,000
Genome size (bp) 3,397,040

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2925

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1023788_0 Male sterility protein K01897 - 6.2.1.3 0.0 1137.0
TH2_k127_1023788_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 361.0
TH2_k127_1023788_2 - - - - 0.0000000000000000000000000000002033 127.0
TH2_k127_1023788_3 Peptidase family M1 domain - - - 0.000000000000000000000000004122 121.0
TH2_k127_102995_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 588.0
TH2_k127_102995_1 - - - - 0.00000000000000000000001287 107.0
TH2_k127_1035668_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 318.0
TH2_k127_1035668_1 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003121 271.0
TH2_k127_1035668_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000191 140.0
TH2_k127_1035668_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000008397 64.0
TH2_k127_106300_0 Homologues of snake disintegrins - - - 0.0000000000000000000000000000000000000000000000000000000000000000005995 249.0
TH2_k127_106300_1 - - - - 0.00000000000000000000000000000000000000000000000146 194.0
TH2_k127_106300_2 S-adenosylhomocysteine deaminase activity K01305,K15358 - 3.5.2.18 0.0000000398 62.0
TH2_k127_1064888_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 541.0
TH2_k127_1064888_1 Receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 353.0
TH2_k127_1064888_2 Acid phosphatase homologues K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000004452 81.0
TH2_k127_10685_0 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 3.785e-267 832.0
TH2_k127_10685_1 COG0659 Sulfate permease and related transporters (MFS superfamily) K01673,K03321 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 557.0
TH2_k127_10685_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000002236 236.0
TH2_k127_10685_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000004012 185.0
TH2_k127_10685_4 Cold-shock protein K03704 - - 0.000000000000000000000000000000000005688 137.0
TH2_k127_1084510_0 tRNA synthetases class II (D, K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 362.0
TH2_k127_1084510_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000004102 234.0
TH2_k127_1084510_2 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000001578 117.0
TH2_k127_1084510_3 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000001321 70.0
TH2_k127_1098717_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003929 233.0
TH2_k127_1098717_3 FecR protein - - - 0.00000000000000000000000000000000000000008864 162.0
TH2_k127_1123758_0 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000002308 203.0
TH2_k127_1123758_1 Domain of unknown function (DUF4920) - - - 0.0000000000000000000000000000000000000000000000000003325 191.0
TH2_k127_1125613_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 544.0
TH2_k127_1125613_1 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004336 283.0
TH2_k127_1125613_2 PHB de-polymerase C-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000001744 239.0
TH2_k127_1125613_3 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000004619 139.0
TH2_k127_1125613_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000418 49.0
TH2_k127_1136307_0 Ribosomal large subunit pseudouridine synthase A K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 411.0
TH2_k127_1136307_1 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 394.0
TH2_k127_1136307_2 RmlD substrate binding domain K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 394.0
TH2_k127_1141377_0 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 472.0
TH2_k127_1141377_1 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 355.0
TH2_k127_1141377_2 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 293.0
TH2_k127_1141377_3 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003651 282.0
TH2_k127_1141377_4 PKD domain - - - 0.0000000000000000000000000000000000003014 163.0
TH2_k127_1141377_5 Ankyrin repeat - - - 0.000000008055 63.0
TH2_k127_1141377_6 - - - - 0.00008123 52.0
TH2_k127_1148554_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000077 237.0
TH2_k127_1148554_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000005581 110.0
TH2_k127_1148554_3 Protein of unknown function (DUF1571) - - - 0.0000000001098 72.0
TH2_k127_1155970_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000009738 215.0
TH2_k127_1160173_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 593.0
TH2_k127_1160173_1 R3H domain K06346,K09749 - - 0.0000000000000000000000001338 123.0
TH2_k127_1160173_2 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000003163 110.0
TH2_k127_1160173_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000004004 101.0
TH2_k127_1160173_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000008363 60.0
TH2_k127_1165796_0 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001779 289.0
TH2_k127_1165796_1 KR domain K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000348 236.0
TH2_k127_1165796_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000201 212.0
TH2_k127_1165796_3 Endonuclease Exonuclease Phosphatase K05349,K18353 - 3.2.1.21 0.00000000000000000000000000002376 136.0
TH2_k127_1165796_5 - - - - 0.000000000006715 72.0
TH2_k127_1167623_0 repeat protein - - - 1.211e-219 706.0
TH2_k127_1167623_1 peptidyl-tyrosine sulfation - - - 0.00000000000000005729 84.0
TH2_k127_1173825_1 cell adhesion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 309.0
TH2_k127_1176032_0 peptidase U62 modulator of DNA gyrase - - - 2.25e-259 809.0
TH2_k127_1176032_1 Metalloenzyme superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 341.0
TH2_k127_1176032_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000004067 236.0
TH2_k127_1176032_3 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000001141 199.0
TH2_k127_1176032_4 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000002646 164.0
TH2_k127_1183384_0 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000003135 164.0
TH2_k127_1183384_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.000000000000000000000000000006041 126.0
TH2_k127_1183384_2 Psort location Cytoplasmic, score 8.96 K07220 - - 0.000000000000000005068 93.0
TH2_k127_1190311_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 381.0
TH2_k127_1190311_1 heme binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 329.0
TH2_k127_1190311_2 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 316.0
TH2_k127_1194491_0 ABC transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 442.0
TH2_k127_1208690_0 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 344.0
TH2_k127_1208690_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000002074 143.0
TH2_k127_1208690_2 Transcriptional regulator, AbiEi antitoxin - - - 0.000000000000000000000007148 115.0
TH2_k127_1215361_0 Phosphate acyltransferases K00631 - 2.3.1.15 0.0 1035.0
TH2_k127_1222620_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.604e-223 701.0
TH2_k127_1222620_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 449.0
TH2_k127_1222620_2 PFAM PHP domain protein K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000003034 260.0
TH2_k127_1222620_3 BMC - - - 0.00000000000000000000000000000000000002458 159.0
TH2_k127_123102_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01874 - 6.1.1.10 1.578e-308 957.0
TH2_k127_123102_1 - - - - 0.0000000000000000000000000000001495 142.0
TH2_k127_123102_3 aminopeptidase N - - - 0.0001769 49.0
TH2_k127_1235568_0 Tetratricopeptide repeat - - - 4.165e-237 751.0
TH2_k127_1235568_1 PFAM Glycosyl hydrolases family 39 K21000 - - 0.00000000000000002908 94.0
TH2_k127_1260239_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 542.0
TH2_k127_1260239_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000001109 220.0
TH2_k127_1261422_0 Thioredoxin - - - 0.00000000000000000000000000000000002885 145.0
TH2_k127_1261422_1 - - - - 0.00001315 58.0
TH2_k127_1264330_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 582.0
TH2_k127_1264330_1 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 352.0
TH2_k127_1264330_2 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002638 261.0
TH2_k127_1264330_3 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000001053 233.0
TH2_k127_1264330_4 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000001318 207.0
TH2_k127_1264398_0 amine dehydrogenase activity K14647,K21449 - - 0.000000009063 68.0
TH2_k127_1268345_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 1.523e-209 660.0
TH2_k127_1268345_1 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 301.0
TH2_k127_1268345_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000004031 249.0
TH2_k127_1286615_0 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 3.383e-243 758.0
TH2_k127_1286615_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.433e-209 662.0
TH2_k127_1286615_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 528.0
TH2_k127_1286615_3 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001716 250.0
TH2_k127_1286615_4 cellulase activity K01183 - 3.2.1.14 0.00000000000000003211 96.0
TH2_k127_1288778_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 311.0
TH2_k127_1288778_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000004585 223.0
TH2_k127_1288778_2 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000006317 106.0
TH2_k127_1288778_3 - - - - 0.0000002316 60.0
TH2_k127_1303261_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 280.0
TH2_k127_1303261_1 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000000000000000004114 232.0
TH2_k127_1303261_2 PilZ domain K02676 - - 0.000000000000000000000000000361 126.0
TH2_k127_1309096_1 Sarcosine oxidase K00303 - 1.5.3.1 0.0000000000000000000000000004203 113.0
TH2_k127_1309096_2 - - - - 0.000000000000000001097 98.0
TH2_k127_1316399_0 von Willebrand factor (vWF) type A domain - - - 5.631e-220 702.0
TH2_k127_1322264_0 General secretion pathway protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 568.0
TH2_k127_1322264_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.00000000000000000000000000000000000000000000000000000000787 200.0
TH2_k127_1322264_2 General secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000006332 169.0
TH2_k127_1322264_3 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000000000000000000000000002573 132.0
TH2_k127_1336839_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.514e-283 904.0
TH2_k127_1336839_1 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003331 278.0
TH2_k127_1336839_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000001807 215.0
TH2_k127_1336839_3 Peptidase family M23 K21472 - - 0.000000000000000001617 102.0
TH2_k127_1337505_0 Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 477.0
TH2_k127_1358922_0 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004353 236.0
TH2_k127_1358922_1 CRS1_YhbY K07574 - - 0.00000000000000000000000000000009049 126.0
TH2_k127_1358922_2 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000001895 103.0
TH2_k127_1372106_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004021 276.0
TH2_k127_1372106_1 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000002493 171.0
TH2_k127_1377582_0 Periplasmic protein TonB links inner and outer membranes - - - 0.0 1023.0
TH2_k127_1377582_1 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 351.0
TH2_k127_1377582_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 287.0
TH2_k127_1377582_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 301.0
TH2_k127_1377582_4 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000195 213.0
TH2_k127_1377582_5 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.0000000000000000000000727 103.0
TH2_k127_1377582_6 Hydrolase, TatD family K03424 - - 0.00005007 50.0
TH2_k127_1377644_0 Glycosyltransferase like family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002244 250.0
TH2_k127_1377644_1 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000006469 125.0
TH2_k127_1384386_0 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 400.0
TH2_k127_1384386_1 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 376.0
TH2_k127_1384386_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 351.0
TH2_k127_139776_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 3.727e-223 701.0
TH2_k127_139776_1 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009786 349.0
TH2_k127_139776_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 317.0
TH2_k127_139776_3 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000063 276.0
TH2_k127_139776_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003506 239.0
TH2_k127_139776_5 cyclic nucleotide binding K07001,K10914 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000002993 169.0
TH2_k127_139776_6 - - - - 0.0000000000000000000000000004411 125.0
TH2_k127_1398182_0 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 451.0
TH2_k127_1398182_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000001369 229.0
TH2_k127_1411416_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004064 278.0
TH2_k127_1411416_1 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000000000000000004974 164.0
TH2_k127_1411416_2 Amino acid permease - - - 0.00000000000000000000000000000000003031 142.0
TH2_k127_1411416_3 Amino acid permease - - - 0.0000000000000000000000000000002942 132.0
TH2_k127_1420589_0 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 483.0
TH2_k127_1420589_1 RDD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 310.0
TH2_k127_1420589_2 - K07275 - - 0.00000000000000000000000000378 117.0
TH2_k127_1420589_3 Septum formation - - - 0.0000007924 55.0
TH2_k127_1425236_0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 401.0
TH2_k127_1425236_1 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 367.0
TH2_k127_1425236_2 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 326.0
TH2_k127_1425236_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000003299 219.0
TH2_k127_1425236_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000007927 156.0
TH2_k127_142810_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 373.0
TH2_k127_142810_1 DTW - - - 0.00000000000000000000000000000000000000000001936 169.0
TH2_k127_1446457_0 oxidoreductase activity K11089 - - 0.0000000000000000000000000000000000000000001137 177.0
TH2_k127_1457424_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 478.0
TH2_k127_1457424_1 Thrombospondin type 3 repeat - - - 0.00000000000000000000000000000000000000000000001915 190.0
TH2_k127_1466184_0 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000009222 168.0
TH2_k127_1466184_1 guanyl-nucleotide exchange factor activity K19231,K21449 - - 0.00000009479 65.0
TH2_k127_1468526_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 304.0
TH2_k127_1468526_1 Domain of unknown function (DUF4395) - - - 0.00000000000000001542 89.0
TH2_k127_1471481_0 Belongs to the peptidase S16 family - - - 5.658e-248 791.0
TH2_k127_1471481_1 serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 312.0
TH2_k127_1471481_2 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004045 251.0
TH2_k127_1471481_3 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000007305 158.0
TH2_k127_1471481_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000045 105.0
TH2_k127_1494577_0 Belongs to the ClpA ClpB family K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 518.0
TH2_k127_1494577_1 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 380.0
TH2_k127_1494577_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000006391 145.0
TH2_k127_1494577_3 - - - - 0.0000000000000000000000000000000001559 134.0
TH2_k127_1495808_0 DNA polymerase beta thumb K02347 - - 4.865e-206 665.0
TH2_k127_1495808_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 331.0
TH2_k127_1495808_2 nitrite reductase [NAD(P)H] activity K05710 - - 0.00000000000000000000000000000000002712 157.0
TH2_k127_1495808_3 Protein of unknown function (DUF2400) - - - 0.00000000165 66.0
TH2_k127_1540494_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 483.0
TH2_k127_1540494_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 384.0
TH2_k127_1540494_2 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 340.0
TH2_k127_1540494_3 COG2755 Lysophospholipase L1 and related esterases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 307.0
TH2_k127_1540494_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000003539 232.0
TH2_k127_1540494_5 Stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000000000000001177 195.0
TH2_k127_1540494_6 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000005919 126.0
TH2_k127_1540494_8 protein kinase activity K12132 - 2.7.11.1 0.0000007356 60.0
TH2_k127_1558434_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 1.695e-211 695.0
TH2_k127_1563047_0 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 391.0
TH2_k127_1563047_1 - - - - 0.000838 46.0
TH2_k127_1563047_2 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0009538 45.0
TH2_k127_1565049_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 476.0
TH2_k127_1565049_1 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000000001991 250.0
TH2_k127_1572621_1 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000000000000000000000000000000000007932 185.0
TH2_k127_1572621_2 amine dehydrogenase activity K14647,K21449 - - 0.00000000000003929 85.0
TH2_k127_1573697_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 3.985e-203 639.0
TH2_k127_1575790_0 BadF/BadG/BcrA/BcrD ATPase family K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 419.0
TH2_k127_1575790_1 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 380.0
TH2_k127_1575790_2 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000002468 227.0
TH2_k127_1580035_0 ABC transporter K06020 - 3.6.3.25 2.946e-293 914.0
TH2_k127_1580035_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 9.215e-244 779.0
TH2_k127_1580035_2 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 374.0
TH2_k127_1580035_3 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000006638 114.0
TH2_k127_1580035_4 Thioesterase-like superfamily - - - 0.00000000000000000000001462 118.0
TH2_k127_1580035_5 SOCS_box - - - 0.0000000000001936 78.0
TH2_k127_1607728_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 485.0
TH2_k127_1607728_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008185 329.0
TH2_k127_1607728_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 308.0
TH2_k127_1607728_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000004971 138.0
TH2_k127_1627221_0 Domain of unknown function (DUF4178) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 462.0
TH2_k127_1629278_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 1.163e-196 624.0
TH2_k127_1629278_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 304.0
TH2_k127_163727_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 366.0
TH2_k127_163727_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007689 269.0
TH2_k127_164229_0 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001971 275.0
TH2_k127_164229_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007679 269.0
TH2_k127_164229_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000005433 198.0
TH2_k127_164229_3 - - - - 0.000000000000001256 83.0
TH2_k127_1643660_0 TonB dependent receptor K02014 - - 2.442e-275 876.0
TH2_k127_1643660_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 466.0
TH2_k127_1643660_3 - - - - 0.00000000000000000000000000000000000000000000000007393 185.0
TH2_k127_1643660_4 PEGA domain - - - 0.0000000000000000000000000000000000000000000001789 177.0
TH2_k127_1644600_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 594.0
TH2_k127_1644600_1 - - - - 0.00000000000241 72.0
TH2_k127_1657105_1 Esterase PHB depolymerase K03932 - - 0.000000000000000000001853 110.0
TH2_k127_1657105_2 Major Facilitator Superfamily K03301 - - 0.0000005652 63.0
TH2_k127_1659952_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1059.0
TH2_k127_1659952_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000006533 145.0
TH2_k127_1659952_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075 GO:0008150,GO:0040007 2.4.2.8,6.3.4.19 0.0007236 47.0
TH2_k127_1694347_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000006066 213.0
TH2_k127_1694347_1 integral membrane protein - - - 0.000000000000000008174 94.0
TH2_k127_1694347_2 AntiSigma factor - - - 0.00000000000000002249 88.0
TH2_k127_1694347_3 Protein of unknown function (DUF3106) - - - 0.000000000002621 76.0
TH2_k127_1708923_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 7.78e-244 756.0
TH2_k127_1708923_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 327.0
TH2_k127_1708923_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000001538 244.0
TH2_k127_1708923_3 SecE/Sec61-gamma subunits of protein translocation complex K03073 - - 0.00000000000000000000000000000000000000000000000521 175.0
TH2_k127_1708923_4 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000219 102.0
TH2_k127_1708923_5 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000006693 93.0
TH2_k127_1708923_6 - - - - 0.000000001371 63.0
TH2_k127_1708923_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000003036 50.0
TH2_k127_1720123_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 533.0
TH2_k127_1720123_1 - - - - 0.00000000000000000000000000000000000000000000002726 174.0
TH2_k127_1720123_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000007989 169.0
TH2_k127_1747921_0 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 455.0
TH2_k127_1830216_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003652 262.0
TH2_k127_1830216_1 Homeodomain-like domain K03088 - - 0.0000000000000000000000000000000000000000000000000000000000002582 218.0
TH2_k127_1832128_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000444 135.0
TH2_k127_1832128_2 - - - - 0.0000000000000000000000000003025 127.0
TH2_k127_1832128_3 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.00000000000000000007511 89.0
TH2_k127_1849033_0 TonB dependent receptor - - - 0.0 1052.0
TH2_k127_1849033_1 Radical SAM - - - 6.65e-220 692.0
TH2_k127_1849033_2 - - - - 0.000000000000000000000000003467 121.0
TH2_k127_1871506_0 DisA bacterial checkpoint controller nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 473.0
TH2_k127_1871506_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 415.0
TH2_k127_1871506_2 COGs COG1233 Phytoene dehydrogenase and related protein K09835 - 5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 435.0
TH2_k127_1871506_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 400.0
TH2_k127_1871506_4 histone H2A K63-linked ubiquitination K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 318.0
TH2_k127_1871506_5 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000000000000000000000000006976 206.0
TH2_k127_1882780_0 DEAD/H associated K03724 - - 2.053e-226 712.0
TH2_k127_1882780_1 aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 440.0
TH2_k127_1882780_2 Fic/DOC family K07341 - - 0.00000000000000000000000000000000001702 142.0
TH2_k127_1882780_3 PFAM SpoVT AbrB K07172,K18842 - - 0.0000000000001028 74.0
TH2_k127_1891470_0 Belongs to the peptidase S8 family - - - 6.079e-223 712.0
TH2_k127_1891470_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000005151 215.0
TH2_k127_1891470_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000005407 121.0
TH2_k127_1897098_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 422.0
TH2_k127_1897098_1 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001351 295.0
TH2_k127_1900858_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 418.0
TH2_k127_1900858_1 aminopeptidase N - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 345.0
TH2_k127_1900858_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000000000000001581 93.0
TH2_k127_1906823_0 tRNA nucleotidyltransferase domain 2 putative K00974 - 2.7.7.72 0.000000000000000000000000000000000000001146 150.0
TH2_k127_1906823_1 response regulator - - - 0.00000000000001243 86.0
TH2_k127_1911411_0 Belongs to the heat shock protein 70 family K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 434.0
TH2_k127_1914471_0 Vitamin K epoxide reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 451.0
TH2_k127_1914471_1 Membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 421.0
TH2_k127_1914471_2 short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 356.0
TH2_k127_1914471_3 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 323.0
TH2_k127_1914471_4 Transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000002963 196.0
TH2_k127_1914471_5 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000001008 190.0
TH2_k127_1918977_0 IgGFc binding protein - - - 0.00000000000000000000001897 117.0
TH2_k127_1922797_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.349e-229 718.0
TH2_k127_1922797_1 Transglycosylase K08309 - - 0.0000001858 57.0
TH2_k127_192414_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1063.0
TH2_k127_192414_1 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 557.0
TH2_k127_192414_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 371.0
TH2_k127_1940762_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 5.657e-226 706.0
TH2_k127_1944981_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0 1138.0
TH2_k127_1966497_0 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 564.0
TH2_k127_1966497_1 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 501.0
TH2_k127_1966497_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000002781 174.0
TH2_k127_1974445_0 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000004136 98.0
TH2_k127_1974445_1 COG1413 FOG HEAT repeat K22221 - - 0.0000002071 64.0
TH2_k127_1974445_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00003895 53.0
TH2_k127_1977755_0 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 606.0
TH2_k127_1977755_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002041 265.0
TH2_k127_199154_0 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 486.0
TH2_k127_199154_2 metal-dependent membrane protease K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000001622 250.0
TH2_k127_1992874_0 B12 binding domain - - - 4.866e-235 739.0
TH2_k127_1992874_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 397.0
TH2_k127_1992874_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000159 258.0
TH2_k127_1995738_0 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416,K02417,K03225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 411.0
TH2_k127_1995738_1 - - - - 0.00000000000000000000000000000000000000000000000000000000007951 223.0
TH2_k127_1995738_2 YscO-like protein - - - 0.000000000000000000000000000000000000000000000000000005763 194.0
TH2_k127_1995738_3 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412,K03224 - 3.6.3.14 0.00001425 47.0
TH2_k127_2017198_0 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000000000000000000003299 219.0
TH2_k127_2017198_1 NACHT domain - - - 0.0000000000000000000000000002142 132.0
TH2_k127_2017198_2 intracellular signal transduction K01768 - 4.6.1.1 0.000002198 61.0
TH2_k127_202357_0 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000003338 269.0
TH2_k127_202357_1 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000287 164.0
TH2_k127_202357_2 - - - - 0.00000000000000000000000006646 124.0
TH2_k127_202357_3 - - - - 0.00000000007368 76.0
TH2_k127_2026917_0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 488.0
TH2_k127_2026917_1 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 292.0
TH2_k127_2026917_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000003562 207.0
TH2_k127_2033732_0 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 3.013e-245 764.0
TH2_k127_2033732_1 PEGA domain - - - 0.000001043 60.0
TH2_k127_2042035_0 - - - - 0.0000001567 64.0
TH2_k127_2044771_0 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.0 1009.0
TH2_k127_2044771_1 oxidoreductase K00311,K00313 - 1.5.5.1 1.917e-274 856.0
TH2_k127_2044771_2 PFAM Electron transfer flavoprotein alpha beta-subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 414.0
TH2_k127_2044771_3 electron transfer activity K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 388.0
TH2_k127_2044771_4 WD40-like Beta Propeller Repeat - - - 0.00000000001291 75.0
TH2_k127_2050619_0 Peptidase family M28 - - - 0.0 1169.0
TH2_k127_2050619_1 Peptidase family M1 domain K01256,K08776 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 596.0
TH2_k127_2050619_2 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000009591 261.0
TH2_k127_2080751_1 spermidine synthase activity - - - 0.00000000000000000004788 102.0
TH2_k127_2080751_2 positive regulation of growth - - - 0.000000000006282 67.0
TH2_k127_2101287_0 ATPase family associated with various cellular activities (AAA) - - - 9.725e-250 777.0
TH2_k127_2101287_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 386.0
TH2_k127_2101287_2 Bacterial pre-peptidase C-terminal domain K14645 - - 0.00000000000000000000000000000000000000000599 173.0
TH2_k127_2101287_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000002032 111.0
TH2_k127_2101287_4 triphosphatase activity - - - 0.000000000000000000001885 104.0
TH2_k127_2101287_5 PilZ domain - - - 0.000000000000000000005194 96.0
TH2_k127_2127541_0 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000000018 241.0
TH2_k127_2127541_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000001095 153.0
TH2_k127_2127541_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000001452 69.0
TH2_k127_2130800_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 474.0
TH2_k127_2130800_1 COG1073 hydrolases of the alpha beta superfamily - - - 0.00000000000000000002534 103.0
TH2_k127_2136017_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 384.0
TH2_k127_2136017_1 NUDIX domain - - - 0.0000000000000000000000000000000000000000004531 166.0
TH2_k127_2136017_2 Response regulator receiver - - - 0.000004376 55.0
TH2_k127_213956_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 484.0
TH2_k127_213956_1 Water Stress and Hypersensitive response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001652 284.0
TH2_k127_2139589_0 protein required for cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002082 289.0
TH2_k127_2139589_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000003598 216.0
TH2_k127_2139589_2 - - - - 0.0000000000000000000000000000009549 134.0
TH2_k127_2143089_0 Carboxyl transferase domain - - - 4.142e-267 834.0
TH2_k127_2143089_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 283.0
TH2_k127_2143089_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007624 293.0
TH2_k127_2143089_3 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000005644 248.0
TH2_k127_2143718_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 291.0
TH2_k127_2143718_1 Biopolymer transport protein K03559 - - 0.000000000000000000000000000000000000000000000000000000004631 203.0
TH2_k127_2143718_2 of the alpha beta superfamily K06889 - - 0.000000000000000000001282 97.0
TH2_k127_2143718_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000006061 88.0
TH2_k127_2161961_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.069e-305 944.0
TH2_k127_2161961_1 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 338.0
TH2_k127_2161961_2 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000001013 177.0
TH2_k127_2166621_0 PAP2 superfamily C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000002879 244.0
TH2_k127_2166621_1 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K00567,K01247 - 2.1.1.63,3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000005885 224.0
TH2_k127_2166621_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000001001 104.0
TH2_k127_2166621_3 ATP-binding region, ATPase domain protein - - - 0.00000000000001544 83.0
TH2_k127_2166621_4 OmpA family K03286 - - 0.000000001043 59.0
TH2_k127_2167419_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 352.0
TH2_k127_2167419_1 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001344 253.0
TH2_k127_2167419_2 AMMECR1 - - - 0.000000000000000000000000000000000000000000000001358 189.0
TH2_k127_2194530_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 350.0
TH2_k127_2194530_1 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 321.0
TH2_k127_2194530_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000005148 180.0
TH2_k127_2200734_0 PFAM Helix-turn-helix - - - 0.000000000000000000000000000000000000001046 153.0
TH2_k127_2200734_1 metallopeptidase activity K01183 - 3.2.1.14 0.00000009843 64.0
TH2_k127_2201409_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 529.0
TH2_k127_2201409_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 488.0
TH2_k127_2201409_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 422.0
TH2_k127_2201409_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000001558 93.0
TH2_k127_2201409_4 YcxB-like protein - - - 0.00000000001948 77.0
TH2_k127_2217669_0 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000001227 220.0
TH2_k127_2217669_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000003493 138.0
TH2_k127_2217669_2 Nuclear protein SET K07117 - - 0.0000000000000000156 87.0
TH2_k127_2217669_3 chemotaxis K03408 - - 0.00000001038 67.0
TH2_k127_2217669_4 PFAM MCP methyltransferase, CheR-type K00575 - 2.1.1.80 0.0001691 49.0
TH2_k127_2227254_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 357.0
TH2_k127_2227254_1 - - - - 0.000000000000000000000000000000000000000000000102 181.0
TH2_k127_2227254_2 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000004028 127.0
TH2_k127_2227254_3 - - - - 0.00000000000007322 76.0
TH2_k127_2228212_0 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003461 277.0
TH2_k127_2228212_1 succinyl-diaminopimelate desuccinylase activity K01439 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.00000000000000000000000000001433 134.0
TH2_k127_2230068_0 AMP-binding enzyme K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 328.0
TH2_k127_2230068_2 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000003099 94.0
TH2_k127_2234897_0 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 487.0
TH2_k127_2234897_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 462.0
TH2_k127_2234897_2 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001339 283.0
TH2_k127_2234897_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000001663 83.0
TH2_k127_2234897_4 - K07401 - - 0.0000000000005062 70.0
TH2_k127_2234897_5 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000001425 55.0
TH2_k127_2235590_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.193e-228 713.0
TH2_k127_2235590_1 - - - - 0.0000000000000000000000000000000000000000000000000000001496 199.0
TH2_k127_2235590_2 Histone deacetylase domain - - - 0.00000000000000000000000000000002017 128.0
TH2_k127_2242024_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000001368 200.0
TH2_k127_2242024_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000002125 177.0
TH2_k127_2242024_2 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000004484 129.0
TH2_k127_2242024_3 7TM diverse intracellular signalling - - - 0.0000000000000000000000000003629 121.0
TH2_k127_2242024_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000001772 114.0
TH2_k127_2246579_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000005683 87.0
TH2_k127_2246579_1 - - - - 0.00000000000002846 87.0
TH2_k127_2252003_0 Bacterial regulatory protein, Fis family - - - 1.069e-223 704.0
TH2_k127_2252003_1 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000003857 150.0
TH2_k127_2274455_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 351.0
TH2_k127_2274455_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000001147 195.0
TH2_k127_2274455_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000001859 183.0
TH2_k127_2274782_0 Cation efflux family K16264 - - 0.0000000000000000000000000000000001259 137.0
TH2_k127_2274782_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000783 111.0
TH2_k127_2274782_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000001879 108.0
TH2_k127_2284158_0 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000002443 142.0
TH2_k127_2284158_1 - - - - 0.000000000000000001643 85.0
TH2_k127_2284158_2 Cyclic nucleotide-monophosphate binding domain K04739 - - 0.000000000006114 78.0
TH2_k127_2291143_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 445.0
TH2_k127_2291143_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 362.0
TH2_k127_2291143_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000003194 231.0
TH2_k127_2291143_3 all-trans-retinol 13,14-reductase activity - - - 0.000000000000000000000000000000000000000000000005988 190.0
TH2_k127_2291715_0 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007831 271.0
TH2_k127_2291715_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000003067 215.0
TH2_k127_2291715_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.00003804 53.0
TH2_k127_2303599_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 494.0
TH2_k127_2303599_1 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 419.0
TH2_k127_2304366_0 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 376.0
TH2_k127_2304366_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 323.0
TH2_k127_2304366_2 TIGRFAM phosphate ABC transporter K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000928 302.0
TH2_k127_2304366_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000003011 260.0
TH2_k127_2304366_4 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000001432 249.0
TH2_k127_2304366_5 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000003682 225.0
TH2_k127_2304366_6 Protein of unknown function (DUF1275) - - - 0.0000000000000000000000000000000000000001198 161.0
TH2_k127_2304366_7 - - - - 0.00000000000000000000000000000000000002844 151.0
TH2_k127_2315197_0 Ketoacyl-synthetase C-terminal extension - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 499.0
TH2_k127_2315197_1 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 477.0
TH2_k127_2315197_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 326.0
TH2_k127_2315197_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K13611,K15314,K15337 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00001324 51.0
TH2_k127_2315268_0 Aminotransferase - - - 1.223e-218 687.0
TH2_k127_2315268_1 COG0277 FAD FMN-containing dehydrogenases K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 532.0
TH2_k127_2315268_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005665 273.0
TH2_k127_2315268_3 EVE domain - - - 0.000000000000000000000000000000000000000000007733 166.0
TH2_k127_2315268_4 Glutaredoxin-like domain (DUF836) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000113 68.0
TH2_k127_2327031_0 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 293.0
TH2_k127_2327031_1 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000000008401 246.0
TH2_k127_2327031_2 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000008227 217.0
TH2_k127_2327031_3 transcriptional regulator, Rrf2 family - - - 0.00000000000000003073 88.0
TH2_k127_2327031_4 - - - - 0.00002219 50.0
TH2_k127_2328775_0 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000007374 119.0
TH2_k127_2332265_0 COGs COG0659 Sulfate permease and related transporter (MFS superfamily) K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000547 584.0
TH2_k127_2332265_1 LysR substrate binding domain K03717 - - 0.00000004596 56.0
TH2_k127_2332265_2 - - - - 0.0001112 51.0
TH2_k127_2342690_0 TonB dependent receptor K16092 - - 9.446e-209 670.0
TH2_k127_2342690_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000009748 213.0
TH2_k127_2342690_2 response regulator K02282,K02482 - 2.7.13.3 0.0000000000000000000000000000000000000007195 166.0
TH2_k127_2342690_3 - - - - 0.000000000000000000001156 104.0
TH2_k127_2342690_4 protein kinase activity - - - 0.0002556 53.0
TH2_k127_2353426_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 358.0
TH2_k127_2353426_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002648 266.0
TH2_k127_2353426_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000001516 68.0
TH2_k127_2353426_3 - - - - 0.00001482 52.0
TH2_k127_2354262_0 ATPase domain of DNA mismatch repair MUTS family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 603.0
TH2_k127_2354262_1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006797 308.0
TH2_k127_2354262_2 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000006464 205.0
TH2_k127_2354262_3 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000000000006988 131.0
TH2_k127_2354262_4 Belongs to the peptidase S8 family K13276 - - 0.0000000000000003242 93.0
TH2_k127_2358945_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.894e-254 791.0
TH2_k127_2358945_1 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 404.0
TH2_k127_2358945_2 fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 336.0
TH2_k127_2358945_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000002161 147.0
TH2_k127_2358945_4 - - - - 0.00000000001359 78.0
TH2_k127_2365038_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 463.0
TH2_k127_2365038_1 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0004395 45.0
TH2_k127_2380088_0 OmpA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 473.0
TH2_k127_2380088_1 Periplasmic protein TonB links inner and outer membranes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 318.0
TH2_k127_2380088_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000005799 153.0
TH2_k127_238783_0 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000001866 242.0
TH2_k127_238783_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000001175 213.0
TH2_k127_238783_2 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 GO:0005575,GO:0005576 1.3.3.11 0.0000000000000000000000000000000000000000000000000000001905 201.0
TH2_k127_238783_3 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000001996 136.0
TH2_k127_2389360_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 307.0
TH2_k127_2389360_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000003547 231.0
TH2_k127_2389360_2 Acyltransferase - - - 0.0000000000000000000000000000000000000000003386 178.0
TH2_k127_2389360_3 Domain of unknown function DUF302 - - - 0.00000000000000000000000000006856 132.0
TH2_k127_2389360_4 - - - - 0.000000000003371 79.0
TH2_k127_2390119_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 310.0
TH2_k127_2390119_1 DnaJ C terminal domain K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 322.0
TH2_k127_2390119_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 283.0
TH2_k127_2390119_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000004855 231.0
TH2_k127_2390119_4 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000001052 173.0
TH2_k127_2399244_0 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 290.0
TH2_k127_2400693_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000001713 70.0
TH2_k127_2400693_1 Belongs to the peptidase S8 family - - - 0.00000000001029 78.0
TH2_k127_2400693_2 solute binding protein K02035 - - 0.000033 56.0
TH2_k127_2410317_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.036e-319 989.0
TH2_k127_2410317_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 475.0
TH2_k127_2410317_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000004398 247.0
TH2_k127_2410317_3 - - - - 0.0000000000000000000006257 108.0
TH2_k127_2421404_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 428.0
TH2_k127_2421404_1 cytochrome C peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000001524 258.0
TH2_k127_2421404_2 - - - - 0.00000000000000000000004761 107.0
TH2_k127_2421404_3 Protein of unknown function (DUF1232) - - - 0.0000000004458 63.0
TH2_k127_2426393_0 Tetratricopeptide repeat - - - 5.568e-220 706.0
TH2_k127_2426393_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 348.0
TH2_k127_243308_0 Chemotaxis K13924 - 2.1.1.80,3.1.1.61 4.97e-215 701.0
TH2_k127_243308_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000006113 235.0
TH2_k127_243308_2 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000008783 182.0
TH2_k127_243308_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000004734 167.0
TH2_k127_243308_4 Histidine kinase - - - 0.00000000000000000000149 112.0
TH2_k127_2444400_0 Phosphotransferase enzyme family K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000001319 274.0
TH2_k127_2444400_1 - - - - 0.0000000002801 66.0
TH2_k127_2454864_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 3.012e-287 904.0
TH2_k127_2454864_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 481.0
TH2_k127_2454864_2 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 473.0
TH2_k127_2461833_0 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 374.0
TH2_k127_2461833_1 Belongs to the glycosyl hydrolase 13 family K01200,K01214 - 3.2.1.41,3.2.1.68 0.000000000000000000000000000000000000006641 149.0
TH2_k127_2461833_2 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000002935 134.0
TH2_k127_2461833_3 haloacid dehalogenase-like hydrolase - - - 0.00000000000000002815 83.0
TH2_k127_2463342_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000002179 145.0
TH2_k127_2464231_0 Uncharacterized protein conserved in bacteria (DUF2314) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 441.0
TH2_k127_2464231_1 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 353.0
TH2_k127_2464231_2 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008145 248.0
TH2_k127_2464231_3 Tetratricopeptide repeat - - - 0.00005363 51.0
TH2_k127_2472992_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001509 259.0
TH2_k127_248392_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 7.105e-293 903.0
TH2_k127_248392_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000004453 205.0
TH2_k127_248392_2 - - - - 0.0000000000003451 73.0
TH2_k127_2489311_2 - - - - 0.0000000000000000000000000007335 119.0
TH2_k127_2535241_0 Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 446.0
TH2_k127_2535241_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 390.0
TH2_k127_2535241_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002863 259.0
TH2_k127_2535241_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001194 230.0
TH2_k127_2535241_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000009747 165.0
TH2_k127_2547016_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000003537 162.0
TH2_k127_2550184_0 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 321.0
TH2_k127_2550184_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000001997 227.0
TH2_k127_2550668_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 452.0
TH2_k127_2550668_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 438.0
TH2_k127_2550668_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 319.0
TH2_k127_2550668_3 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000003548 172.0
TH2_k127_2550668_4 - - - - 0.00000000000000000001278 106.0
TH2_k127_2550668_5 Ribosomal L32p protein family K02911 - - 0.000000000000000003367 87.0
TH2_k127_2572583_0 Biotin carboxylase K01941,K01961,K01968 - 6.3.4.14,6.3.4.6,6.4.1.2,6.4.1.4 9.934e-225 704.0
TH2_k127_2572583_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 417.0
TH2_k127_2572583_2 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.00000000000000000000000000000001247 127.0
TH2_k127_25741_0 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 553.0
TH2_k127_25741_1 FBP C-terminal treble-clef zinc-finger - - - 0.000000000000000000000000000000000000006765 150.0
TH2_k127_25741_2 PFAM transcription factor CarD K07736 - - 0.000008509 57.0
TH2_k127_258865_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 7.417e-280 874.0
TH2_k127_258865_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 493.0
TH2_k127_258865_10 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001745 148.0
TH2_k127_258865_11 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000002765 97.0
TH2_k127_258865_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 410.0
TH2_k127_258865_3 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 314.0
TH2_k127_258865_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000009011 238.0
TH2_k127_258865_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002143 222.0
TH2_k127_258865_6 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001314 195.0
TH2_k127_258865_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000002964 177.0
TH2_k127_258865_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000001643 168.0
TH2_k127_258865_9 rRNA binding K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000004341 150.0
TH2_k127_2592520_0 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000003427 203.0
TH2_k127_2592520_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000003131 205.0
TH2_k127_2592520_2 transcriptional regulator - - - 0.0007487 45.0
TH2_k127_2593281_0 Pfam Response regulator receiver K03413 - - 0.00000000001181 74.0
TH2_k127_2593281_1 thiolester hydrolase activity K07000 - - 0.00000009361 64.0
TH2_k127_2597226_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 481.0
TH2_k127_2597226_2 Lysyl oxidase - - - 0.0000000000000000000000000000236 120.0
TH2_k127_2610635_0 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 324.0
TH2_k127_2610635_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases - - - 0.00000000000000002697 84.0
TH2_k127_2610635_2 peptidase - - - 0.0000000001683 71.0
TH2_k127_2622769_0 PFAM ASPIC UnbV domain protein - - - 0.0000000000000000000000000000001736 142.0
TH2_k127_2622769_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000007697 126.0
TH2_k127_2622769_2 Intracellular proteinase inhibitor - - - 0.00000007762 64.0
TH2_k127_263055_0 Flavin containing amine oxidoreductase - - - 1.836e-211 668.0
TH2_k127_263055_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 606.0
TH2_k127_263055_2 Cyclic nucleotide-monophosphate binding domain K04739 - - 0.0000000000000000000000002316 123.0
TH2_k127_2634889_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 562.0
TH2_k127_2634889_1 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.000009475 49.0
TH2_k127_2634889_2 - - - - 0.00000958 53.0
TH2_k127_263969_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K17217 - 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000008322 173.0
TH2_k127_2640678_0 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 328.0
TH2_k127_2640678_1 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000002196 187.0
TH2_k127_2640678_2 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000005903 78.0
TH2_k127_2640678_3 - - - - 0.0007585 46.0
TH2_k127_2652193_0 Tetratricopeptide repeat - - - 1.082e-199 640.0
TH2_k127_2652193_1 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 301.0
TH2_k127_2653899_0 FHA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 433.0
TH2_k127_2653899_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 362.0
TH2_k127_2653899_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000984 347.0
TH2_k127_2653899_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 305.0
TH2_k127_2653899_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000484 261.0
TH2_k127_2653899_5 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000001531 270.0
TH2_k127_2653899_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000002609 158.0
TH2_k127_2657793_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 533.0
TH2_k127_2657793_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 346.0
TH2_k127_2657793_3 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000006442 116.0
TH2_k127_2657793_4 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000989 103.0
TH2_k127_2670603_0 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003489 255.0
TH2_k127_2670603_1 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000007161 171.0
TH2_k127_2670603_2 Phage shock protein A K03969 - - 0.000000000000000000000000000000000001771 143.0
TH2_k127_2670603_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000000001085 108.0
TH2_k127_2679324_0 Predicted membrane protein (DUF2079) K07778 - 2.7.13.3 0.0000000000000000000000000000000000000000005388 178.0
TH2_k127_2679324_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000002863 61.0
TH2_k127_2679930_0 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 466.0
TH2_k127_2682510_0 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000002095 159.0
TH2_k127_2683360_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 472.0
TH2_k127_2683360_1 Dolichol kinase - - - 0.00000000000000000000000000000000000000000000001239 184.0
TH2_k127_2702468_0 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000149 209.0
TH2_k127_2702468_1 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000001868 195.0
TH2_k127_2702468_2 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000001441 151.0
TH2_k127_2702468_3 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000003839 117.0
TH2_k127_2704516_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 4.691e-255 790.0
TH2_k127_2704516_1 all-trans-retinol 13,14-reductase K09516 GO:0001523,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005640,GO:0005737,GO:0005783,GO:0005789,GO:0006066,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0009987,GO:0010817,GO:0012505,GO:0016020,GO:0016101,GO:0016491,GO:0016627,GO:0019867,GO:0031090,GO:0031965,GO:0031967,GO:0031968,GO:0031975,GO:0031984,GO:0034308,GO:0034754,GO:0042175,GO:0042445,GO:0042572,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0051786,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0098588,GO:0098805,GO:0098827,GO:1901615 1.3.99.23 0.000000000000000002729 90.0
TH2_k127_2708223_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 359.0
TH2_k127_2708223_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000882 267.0
TH2_k127_2708223_2 Transcription factor zinc-finger - - - 0.000000000000000000000000000000000000000000000000000000000002419 212.0
TH2_k127_2708223_3 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000002503 194.0
TH2_k127_2711349_0 Bacterial regulatory protein, Fis family K07713 - - 6.67e-201 633.0
TH2_k127_2711349_1 - - - - 0.000000000000000000000000000000000000000000000009178 196.0
TH2_k127_2723694_0 serine-type D-Ala-D-Ala carboxypeptidase activity K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000009289 245.0
TH2_k127_2723694_1 fruit protein - - - 0.000000000000000818 85.0
TH2_k127_272566_0 Vault protein inter-alpha-trypsin domain K07114 - - 2.756e-258 812.0
TH2_k127_2747531_0 Sigma-54 interaction domain K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 379.0
TH2_k127_2747531_1 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000003781 256.0
TH2_k127_2747531_2 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.00000000000000000000000000000000000000000000000000000004687 205.0
TH2_k127_2747531_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000003997 193.0
TH2_k127_2747531_4 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000005871 184.0
TH2_k127_2747531_5 Histidine kinase - - - 0.000000000000000000000000001532 127.0
TH2_k127_2747531_6 Histidine kinase-like ATPases - - - 0.000000000000000000000496 98.0
TH2_k127_2752789_0 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 445.0
TH2_k127_2752789_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002617 264.0
TH2_k127_2752789_2 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.00000000000000000000000000000000000000000000000000005333 197.0
TH2_k127_2760234_0 Coenzyme A transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 375.0
TH2_k127_2760234_1 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 350.0
TH2_k127_2760234_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 310.0
TH2_k127_2760234_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 289.0
TH2_k127_2760234_4 PilZ domain - - - 0.00000000000000000000000000000000000000001317 157.0
TH2_k127_2764059_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 5.774e-312 974.0
TH2_k127_2764059_1 small subunit K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 341.0
TH2_k127_2764059_2 Prokaryotic cytochrome b561 K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004087 268.0
TH2_k127_2764059_3 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000000000000002463 209.0
TH2_k127_2764059_4 HupF/HypC family K04653 - - 0.00000000000000000007426 97.0
TH2_k127_2774394_0 Thioredoxin - - - 1.679e-279 874.0
TH2_k127_2774394_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008351 382.0
TH2_k127_2774394_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000009281 91.0
TH2_k127_2774394_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000001018 74.0
TH2_k127_2778295_0 peptidase S45, penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 313.0
TH2_k127_2781839_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 387.0
TH2_k127_2781839_1 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 362.0
TH2_k127_2781839_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 350.0
TH2_k127_2781839_3 TPR repeat - - - 0.0006973 45.0
TH2_k127_2783834_0 Protein tyrosine kinase - - - 0.00000000000000005028 93.0
TH2_k127_2797762_0 Beta propeller domain - - - 2.288e-211 679.0
TH2_k127_2797762_1 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 392.0
TH2_k127_2797762_2 -acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004806 237.0
TH2_k127_2797762_3 PIN domain - - - 0.000000000000000000000000004403 118.0
TH2_k127_2797762_4 - - - - 0.00000000001793 67.0
TH2_k127_2797762_5 histone H2A K63-linked ubiquitination - - - 0.00003012 50.0
TH2_k127_2797762_6 phosphorelay signal transduction system - - - 0.0007134 51.0
TH2_k127_2811585_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 439.0
TH2_k127_2830289_0 Cytochrome b subunit of the bc complex K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 536.0
TH2_k127_2830289_1 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.00000000000000000000000000000000000006607 151.0
TH2_k127_2830289_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000003445 99.0
TH2_k127_2830289_3 Protein kinase domain - - - 0.000000000000000448 84.0
TH2_k127_2843115_0 OPT oligopeptide transporter protein - - - 1.037e-213 681.0
TH2_k127_2847169_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1515.0
TH2_k127_2847169_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 546.0
TH2_k127_2856068_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000005179 189.0
TH2_k127_2856068_1 G-D-S-L family lipolytic protein - - - 0.0000008408 61.0
TH2_k127_2863934_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 514.0
TH2_k127_2863934_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000001358 247.0
TH2_k127_2863934_2 CheW-like domain - - - 0.0000000000000000000000000000001735 134.0
TH2_k127_2863934_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000001972 117.0
TH2_k127_2863934_4 cheY-homologous receiver domain - - - 0.00000000000002104 74.0
TH2_k127_2867141_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 506.0
TH2_k127_2867141_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 477.0
TH2_k127_2867141_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 419.0
TH2_k127_2867141_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002805 246.0
TH2_k127_2867141_4 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000002177 140.0
TH2_k127_2869731_0 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 415.0
TH2_k127_2869731_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000002574 156.0
TH2_k127_2869731_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000004139 153.0
TH2_k127_2869731_3 FecR protein - - - 0.00000000000000000008618 104.0
TH2_k127_286981_0 Histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 409.0
TH2_k127_286981_1 Sigma-54 interaction domain K10941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 367.0
TH2_k127_2881973_0 Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 9.734e-202 634.0
TH2_k127_2894946_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 379.0
TH2_k127_2894946_1 ECF sigma factor K03088 - - 0.000000000000000000000000000007594 121.0
TH2_k127_2894946_2 AntiSigma factor - - - 0.00000000000000000004539 94.0
TH2_k127_2914490_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 524.0
TH2_k127_2916723_0 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 596.0
TH2_k127_2916723_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000205 300.0
TH2_k127_2916723_2 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000006992 239.0
TH2_k127_2918129_0 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 447.0
TH2_k127_2918129_1 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000001191 177.0
TH2_k127_2929450_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.252e-260 812.0
TH2_k127_2929450_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 488.0
TH2_k127_2929450_2 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006529 264.0
TH2_k127_2943435_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 309.0
TH2_k127_2943435_1 - - - - 0.00000000000000000000000000003789 126.0
TH2_k127_2943987_0 COG1233 Phytoene dehydrogenase and related proteins K09845 - 1.3.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 583.0
TH2_k127_2943987_1 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 529.0
TH2_k127_2943987_2 phytoene synthase K02291 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 329.0
TH2_k127_2945905_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 332.0
TH2_k127_2945905_1 RuvA, C-terminal domain K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000001229 207.0
TH2_k127_2945905_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000003749 198.0
TH2_k127_2945905_3 - - - - 0.000000000000000000000000000000000000001085 160.0
TH2_k127_2957451_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 422.0
TH2_k127_2957451_1 Ferredoxin-type protein napG of Proteobacteria UniRef RepID K02573 - - 0.0000000000000000000000000000000009077 135.0
TH2_k127_2971766_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 580.0
TH2_k127_2971766_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 537.0
TH2_k127_2971766_2 tRNA pseudouridylate synthase B C-terminal domain K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000001583 298.0
TH2_k127_2979016_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 551.0
TH2_k127_2979016_1 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000006481 219.0
TH2_k127_2979016_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000007456 74.0
TH2_k127_2993853_0 protein homooligomerization K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 451.0
TH2_k127_2993853_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 405.0
TH2_k127_2993853_2 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 323.0
TH2_k127_2993853_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002659 248.0
TH2_k127_299466_0 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 5.163e-259 805.0
TH2_k127_299466_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 466.0
TH2_k127_299466_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000004062 213.0
TH2_k127_299466_3 Biotin-requiring enzyme - - - 0.000000000000000000000000000000000000000000000000000000000004113 226.0
TH2_k127_299466_4 hydrogenase maturation protease - - - 0.000000000000000000000000000000000000974 146.0
TH2_k127_3000795_0 amine oxidase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 504.0
TH2_k127_3000795_1 epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 473.0
TH2_k127_3000795_2 Male sterility protein K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 371.0
TH2_k127_3000795_3 Transcription factor zinc-finger - - - 0.0000000000000000000000000000000000000003415 158.0
TH2_k127_3001111_0 helicase domain protein - - - 0.0 1396.0
TH2_k127_3001111_1 SlyX K03745 - - 0.000002137 51.0
TH2_k127_3012_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 4.822e-219 687.0
TH2_k127_3024825_0 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000008431 233.0
TH2_k127_3024825_1 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000001249 161.0
TH2_k127_3024825_2 SMART helix-turn-helix domain protein K15539 - - 0.0000000000000000000000000000000000001221 148.0
TH2_k127_3024825_3 Cytochrome c - - - 0.000000000000000000007392 95.0
TH2_k127_3024825_4 Tetratricopeptide repeat - - - 0.0000000002588 62.0
TH2_k127_3099099_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 449.0
TH2_k127_3099099_1 Vault protein inter-alpha-trypsin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 434.0
TH2_k127_3099099_2 PFAM SEC-C motif K09858 - - 0.000000000000000000000000003434 125.0
TH2_k127_3103226_0 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 470.0
TH2_k127_3103226_1 PFAM MscS Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002921 244.0
TH2_k127_3103779_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 1.083e-252 792.0
TH2_k127_3103779_1 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000008421 160.0
TH2_k127_3121582_0 Heavy-metal resistance - - - 0.00000000000000000000000000007935 124.0
TH2_k127_3121582_1 protein trimerization - - - 0.00000000000000000000000005383 121.0
TH2_k127_3121582_2 Putative metal-binding motif - - - 0.000000000000004913 89.0
TH2_k127_3148056_0 - - - - 0.000000000000000000000000000000000000000000000000001242 196.0
TH2_k127_3148056_1 - - - - 0.0003168 53.0
TH2_k127_3152368_0 - - - - 0.000000000001577 75.0
TH2_k127_3152368_1 lycopene cyclase - - - 0.000000000141 66.0
TH2_k127_315247_0 HmuY protein - - - 0.0000000000000000000000000000000000000000000000132 184.0
TH2_k127_315247_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000009137 144.0
TH2_k127_315247_2 TonB-dependent receptor - - - 0.00000000000000000000000000000551 125.0
TH2_k127_3156735_0 TonB dependent receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 312.0
TH2_k127_3156735_1 Phage derived protein Gp49-like (DUF891) - - - 0.00009429 51.0
TH2_k127_3156735_2 Helix-turn-helix XRE-family like proteins - - - 0.0002412 49.0
TH2_k127_3168043_0 Two component regulator propeller K19693 - - 0.000000000002716 81.0
TH2_k127_3168043_1 methyltransferase - - - 0.00004004 58.0
TH2_k127_3184996_0 cAMP biosynthetic process - - - 0.000000000000000000000000003031 117.0
TH2_k127_3184996_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000006341 76.0
TH2_k127_3184996_2 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.00000000444 69.0
TH2_k127_3184996_3 Tfp pilus assembly protein, major pilin PilA K02650 - - 0.00009902 55.0
TH2_k127_318762_0 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000000000000000000000001227 177.0
TH2_k127_318762_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000003608 186.0
TH2_k127_3189157_0 COG0044 Dihydroorotase and related cyclic amidohydrolases K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 307.0
TH2_k127_3189157_1 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000002989 121.0
TH2_k127_3189157_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000001934 122.0
TH2_k127_3189157_3 PFAM regulatory protein, ArsR K21903 - - 0.0000000000000000000000001106 112.0
TH2_k127_3189157_4 - - - - 0.0000000003881 66.0
TH2_k127_322093_0 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 445.0
TH2_k127_322093_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000001822 162.0
TH2_k127_3245475_0 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 294.0
TH2_k127_3245475_1 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 321.0
TH2_k127_3245475_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001222 292.0
TH2_k127_3245475_3 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000000000000008988 153.0
TH2_k127_3245475_4 - - - - 0.000000000000000000003969 98.0
TH2_k127_3245747_0 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.0000000000000000000000000000000000000000000006717 186.0
TH2_k127_3245747_1 EGF domain, unclasssified subfamily - GO:0001786,GO:0002165,GO:0003002,GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006897,GO:0006909,GO:0006911,GO:0006950,GO:0006952,GO:0007275,GO:0007389,GO:0007399,GO:0007431,GO:0007435,GO:0007444,GO:0007447,GO:0007450,GO:0007552,GO:0007610,GO:0007626,GO:0008150,GO:0008219,GO:0008289,GO:0008345,GO:0009605,GO:0009607,GO:0009611,GO:0009617,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009953,GO:0009987,GO:0010324,GO:0010623,GO:0012501,GO:0016020,GO:0016043,GO:0016192,GO:0016322,GO:0021700,GO:0022008,GO:0022612,GO:0030100,GO:0030154,GO:0030182,GO:0030424,GO:0030537,GO:0031224,GO:0032501,GO:0032502,GO:0032879,GO:0035070,GO:0035071,GO:0035212,GO:0035220,GO:0035222,GO:0035272,GO:0035295,GO:0040008,GO:0042551,GO:0042742,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043207,GO:0043277,GO:0043652,GO:0044424,GO:0044425,GO:0044456,GO:0044464,GO:0045202,GO:0045807,GO:0048102,GO:0048190,GO:0048468,GO:0048469,GO:0048513,GO:0048518,GO:0048522,GO:0048666,GO:0048678,GO:0048699,GO:0048707,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050764,GO:0050766,GO:0050789,GO:0050794,GO:0050803,GO:0050807,GO:0050896,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0060033,GO:0060099,GO:0060100,GO:0060429,GO:0060627,GO:0061024,GO:0065007,GO:0065008,GO:0071695,GO:0071840,GO:0071944,GO:0072341,GO:0097458,GO:0098542,GO:0098657,GO:0098794,GO:0099024,GO:0120025,GO:1904396,GO:1905153,GO:1905155 - 0.0006984 51.0
TH2_k127_3247634_0 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 574.0
TH2_k127_3247634_1 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 337.0
TH2_k127_3247634_2 PilZ domain - - - 0.000002829 55.0
TH2_k127_3256382_0 O-antigen ligase like membrane protein K18814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 376.0
TH2_k127_3256382_1 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000113 181.0
TH2_k127_3266379_0 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000003743 267.0
TH2_k127_3266379_1 - - - - 0.00000000000000000000000000000000000000006599 153.0
TH2_k127_3266379_2 Immune inhibitor A peptidase M6 - - - 0.00000000000005999 83.0
TH2_k127_3269877_0 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 9.092e-239 764.0
TH2_k127_3269877_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 332.0
TH2_k127_3269877_3 cell adhesion involved in biofilm formation - - - 0.00000000000000000004454 107.0
TH2_k127_3269877_4 Worm-specific repeat type 1 - - - 0.00000000000000624 89.0
TH2_k127_3269877_5 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.47 0.000000000007694 72.0
TH2_k127_327985_0 Belongs to the thiolase family K07508 - 2.3.1.16 3.367e-209 655.0
TH2_k127_327985_1 synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 505.0
TH2_k127_327985_2 Eukaryotic integral membrane protein (DUF1751) - - - 0.00000000000000000000000000000000000002209 166.0
TH2_k127_327985_3 - - - - 0.0000000000000000000000005489 105.0
TH2_k127_327985_5 - - - - 0.0000000009091 61.0
TH2_k127_327985_6 domain, Protein - - - 0.000000001774 59.0
TH2_k127_327985_7 PilZ domain K02676 - - 0.0006926 49.0
TH2_k127_3290941_0 von Willebrand factor K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 569.0
TH2_k127_3290941_1 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 552.0
TH2_k127_3290941_2 Four helix bundle sensory module for signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 470.0
TH2_k127_3290941_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 432.0
TH2_k127_3290941_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657,K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000007563 238.0
TH2_k127_3290941_5 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000002592 150.0
TH2_k127_3290941_6 Protease prsW family - - - 0.00000000000000000000000000001943 130.0
TH2_k127_3290941_7 CheC-like family K03410 - - 0.0000000000000000000000000008118 124.0
TH2_k127_3290941_8 domain protein K20276 - - 0.0000000000002156 85.0
TH2_k127_3322868_0 Stage II sporulation protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 599.0
TH2_k127_3322868_1 Acyl-CoA dehydrogenase, C-terminal domain K00249,K11731 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000002544 193.0
TH2_k127_3322868_2 - - - - 0.0004918 50.0
TH2_k127_3325783_0 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006594 276.0
TH2_k127_3325783_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000003724 134.0
TH2_k127_3327210_0 DNA helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 588.0
TH2_k127_3327210_1 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000001863 205.0
TH2_k127_3327210_2 epimerase K00091,K01007,K02377,K07118,K19073,K19267 - 1.1.1.219,1.1.1.271,1.3.1.75,1.6.5.2,2.7.9.2 0.0000003013 54.0
TH2_k127_3337505_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 452.0
TH2_k127_3337505_1 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 391.0
TH2_k127_3337505_2 Alg9-like mannosyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000109 195.0
TH2_k127_3337505_3 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000002684 156.0
TH2_k127_3337505_4 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.00000000000000000000000000000000001951 143.0
TH2_k127_3347835_0 Arsenical pump membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 478.0
TH2_k127_3347835_1 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002602 300.0
TH2_k127_3347835_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004988 267.0
TH2_k127_334836_0 FAD dependent oxidoreductase - - - 5.119e-195 617.0
TH2_k127_3352449_0 acyl-CoA dehydrogenase K09456,K20035 - - 1.308e-282 880.0
TH2_k127_3352449_1 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.0000000000000000000000000000000000000000000000000000000005553 209.0
TH2_k127_3352449_2 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000003355 123.0
TH2_k127_3356679_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 5.246e-281 880.0
TH2_k127_3356679_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 526.0
TH2_k127_3359570_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000001237 159.0
TH2_k127_3359570_2 protein SCO1 SenC K07152 - - 0.0000000000000000000000000000005426 136.0
TH2_k127_3359570_3 oxidoreductase activity K07114 - - 0.0000000000000000000000007803 120.0
TH2_k127_3359570_4 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000000006098 83.0
TH2_k127_3359570_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.0000000008199 70.0
TH2_k127_3359570_6 - - - - 0.000000007903 65.0
TH2_k127_3359570_7 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.0000002378 63.0
TH2_k127_3359570_8 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000003405 61.0
TH2_k127_3366843_0 COG1233 Phytoene dehydrogenase and related proteins K09516 - 1.3.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 406.0
TH2_k127_3366843_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002102 248.0
TH2_k127_3371159_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 597.0
TH2_k127_3371159_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 591.0
TH2_k127_3371159_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 433.0
TH2_k127_3371159_3 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 407.0
TH2_k127_3371159_4 PFAM response regulator receiver K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 308.0
TH2_k127_3371159_5 Histidine phosphatase superfamily (branch 1) K08296 - - 0.0000000000000000000000000004542 120.0
TH2_k127_3376474_0 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000002507 144.0
TH2_k127_3378896_0 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000000000003358 231.0
TH2_k127_3378896_1 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000385 167.0
TH2_k127_3378896_2 PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K00648 - 2.3.1.180 0.0000000000000008465 91.0
TH2_k127_3378896_3 Catalyzes the formation of trans-2- enoyl-CoA from 2,4-dienoyl-CoA K00219 - 1.3.1.34 0.000000002387 70.0
TH2_k127_3378896_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000028 63.0
TH2_k127_3389917_0 Alg9-like mannosyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007083 286.0
TH2_k127_3389917_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003649 275.0
TH2_k127_3402400_0 Participates in both transcription termination and antitermination K02600 - - 7.443e-278 871.0
TH2_k127_3402400_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 411.0
TH2_k127_3402400_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 344.0
TH2_k127_3402400_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000005266 233.0
TH2_k127_3402400_4 Protein of unknown function (DUF971) - - - 0.0000001812 54.0
TH2_k127_3403378_0 HD domain - - - 2.062e-203 652.0
TH2_k127_3403378_1 TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 340.0
TH2_k127_3403378_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000003113 232.0
TH2_k127_3403378_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000005864 164.0
TH2_k127_3403378_4 Nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000433 125.0
TH2_k127_3403798_0 MreB/Mbl protein K04043 - - 8.549e-293 904.0
TH2_k127_3403798_1 glutamine amidotransferase - - - 0.0000000000000000000000143 104.0
TH2_k127_3405164_0 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 415.0
TH2_k127_3405164_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 334.0
TH2_k127_3405164_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000001626 154.0
TH2_k127_3405164_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000001487 130.0
TH2_k127_3405402_0 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 293.0
TH2_k127_3405402_1 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000021 198.0
TH2_k127_3407818_0 Peptidase dimerisation domain - - - 9.809e-232 724.0
TH2_k127_3407818_1 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 367.0
TH2_k127_3407818_2 Putative RNA methylase family UPF0020 K07444 - - 0.00000000000000000000000000000000000000000000001224 176.0
TH2_k127_3407818_3 chlorophyll binding - - - 0.00000000000000000000000000001731 122.0
TH2_k127_3407818_4 RNA methylase K07444 - - 0.00000000000000000000004324 106.0
TH2_k127_3407818_5 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000002388 69.0
TH2_k127_3407821_1 cyclic-guanylate-specific phosphodiesterase activity - - - 0.000000000009894 75.0
TH2_k127_3407821_2 Thioesterase K07107 - - 0.000000001278 66.0
TH2_k127_3407821_3 PilZ domain K02676 - - 0.00001961 53.0
TH2_k127_341015_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 446.0
TH2_k127_341015_1 HemY protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003336 269.0
TH2_k127_341015_2 SNARE associated Golgi protein - - - 0.0000000001244 62.0
TH2_k127_341015_3 Inner membrane component of T3SS, cytoplasmic domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.000001509 57.0
TH2_k127_3412905_0 Cyclic nucleotide-monophosphate binding domain - - - 2.9e-210 677.0
TH2_k127_3412905_1 - - - - 0.000000000000000000000000000000000000000831 155.0
TH2_k127_3412905_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000007536 140.0
TH2_k127_3413219_0 Peptidase S46 - - - 2.16e-240 762.0
TH2_k127_3413219_1 Belongs to the methyltransferase superfamily K06969,K12297 - 2.1.1.173,2.1.1.191,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 319.0
TH2_k127_3413219_2 Pas domain K02660,K07315 - 3.1.3.3 0.0000002512 58.0
TH2_k127_3413219_3 - - - - 0.00002593 48.0
TH2_k127_341352_0 Large extracellular alpha-helical protein - - - 0.0 1274.0
TH2_k127_3419973_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 404.0
TH2_k127_3422194_0 transcription factor binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 354.0
TH2_k127_3422194_1 Family membership K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000008735 229.0
TH2_k127_3423680_0 ABC transporter K06147,K06148 - - 1.872e-255 799.0
TH2_k127_3423680_1 - - - - 0.0000000001112 64.0
TH2_k127_3433232_0 PFAM FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 456.0
TH2_k127_3433232_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 436.0
TH2_k127_3433232_2 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 364.0
TH2_k127_343706_1 Peptidase family M1 domain K01256 - 3.4.11.2 0.0000000000000000000000000003958 132.0
TH2_k127_343706_2 DNA alkylation repair - - - 0.00000000000000002559 85.0
TH2_k127_343706_3 START domain - - - 0.00000000000673 74.0
TH2_k127_343706_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362,K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0022900,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0072592,GO:0097159,GO:1901265,GO:1901363 1.6.3.4,1.7.1.15 0.0002677 46.0
TH2_k127_343706_5 Calcineurin-like phosphoesterase K06953 - - 0.0008015 48.0
TH2_k127_3439145_0 DEAD DEAH box helicase - - - 1.387e-304 953.0
TH2_k127_3439145_1 PFAM Glycosyl transferase family 2 - - - 1.65e-236 740.0
TH2_k127_3439145_2 Male sterility protein K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 460.0
TH2_k127_3439145_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 470.0
TH2_k127_3439145_4 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 451.0
TH2_k127_3439145_5 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 337.0
TH2_k127_3439145_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002405 285.0
TH2_k127_3439145_7 Putative auto-transporter adhesin, head GIN domain - - - 0.00008529 48.0
TH2_k127_3446697_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 482.0
TH2_k127_3446697_1 thiolester hydrolase activity - - - 0.0000000000000000001988 103.0
TH2_k127_3457743_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K12276 - - 0.000000000000000000000000000000000002272 153.0
TH2_k127_3457743_1 cellulose binding K12132 - 2.7.11.1 0.000000000000000000000000000007796 139.0
TH2_k127_3457743_2 heat shock protein binding - - - 0.0001791 51.0
TH2_k127_3465471_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 4.017e-229 724.0
TH2_k127_3465471_1 short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 454.0
TH2_k127_3465471_2 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000001638 190.0
TH2_k127_3472006_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 333.0
TH2_k127_3472006_1 Stage II sporulation D domain protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001569 269.0
TH2_k127_3472355_0 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000003617 233.0
TH2_k127_3472355_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000978 118.0
TH2_k127_3472355_2 Parallel beta-helix repeats - - - 0.0001175 55.0
TH2_k127_3474571_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 5.564e-296 917.0
TH2_k127_3474571_1 Aminotransferase K14267,K14287 - 2.6.1.17,2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 511.0
TH2_k127_3474571_2 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000885 222.0
TH2_k127_3474571_4 PHP domain protein - - - 0.0000000000006621 81.0
TH2_k127_3479453_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 321.0
TH2_k127_3479453_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 305.0
TH2_k127_3479453_2 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005031 283.0
TH2_k127_3480427_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000002059 248.0
TH2_k127_3480427_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000634 181.0
TH2_k127_3480427_2 DoxX K15977 - - 0.0000000000000000000000000000002289 133.0
TH2_k127_3480427_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000002181 101.0
TH2_k127_3482310_0 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 421.0
TH2_k127_3482310_1 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 367.0
TH2_k127_3482310_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002618 280.0
TH2_k127_3482310_3 protein kinase activity - - - 0.00000000000000000000000006365 124.0
TH2_k127_3488231_0 Sodium:sulfate symporter transmembrane region K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 550.0
TH2_k127_3488231_1 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000000000000000000000000000000000000009551 220.0
TH2_k127_3488231_3 Protein conserved in bacteria - - - 0.0000006492 53.0
TH2_k127_3506575_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 481.0
TH2_k127_3506575_1 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002333 280.0
TH2_k127_3506575_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000002873 154.0
TH2_k127_3506575_3 redox protein, regulator of disulfide bond formation - - - 0.000000000002316 75.0
TH2_k127_3506575_5 Protein of unknown function (DUF2846) - - - 0.00002928 55.0
TH2_k127_3513037_0 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005616 256.0
TH2_k127_3513037_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000004018 160.0
TH2_k127_3513037_2 guanyl-nucleotide exchange factor activity K19231,K21449 - - 0.00000000002783 74.0
TH2_k127_3514836_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 363.0
TH2_k127_3514836_1 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002596 259.0
TH2_k127_3523286_0 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009150,GO:0009165,GO:0009259,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034654,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 433.0
TH2_k127_3523286_1 - - - - 0.0000000000000000000000000000002552 143.0
TH2_k127_3531827_0 domain, Protein - - - 0.000000000000000000000000000008365 121.0
TH2_k127_3531827_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000003039 72.0
TH2_k127_3533003_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 321.0
TH2_k127_3533003_1 - - - - 0.000000000000000000000000136 119.0
TH2_k127_3552171_0 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 385.0
TH2_k127_3552171_2 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000015 231.0
TH2_k127_3552171_3 protein domain associated with - - - 0.0000000000000000000000000000000000000000000000000000000000002014 223.0
TH2_k127_3553253_0 ATPase family associated with various cellular activities (AAA) - - - 8.404e-287 889.0
TH2_k127_3553253_1 Alpha-2-macroglobulin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 334.0
TH2_k127_3565021_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1545.0
TH2_k127_3565021_1 Alpha-2-Macroglobulin K06894 - - 2.045e-243 787.0
TH2_k127_3565021_2 N-4 methylation of cytosine K00571,K03497 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000001148 265.0
TH2_k127_3565021_3 Putative serine esterase (DUF676) - - - 0.000000000000000000000000000000000000000000000000000001088 211.0
TH2_k127_3565021_4 Cytochrome c K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000002572 201.0
TH2_k127_357472_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000001855 154.0
TH2_k127_357472_2 - - - - 0.00000000000000002674 89.0
TH2_k127_3576396_0 Heat shock 70 kDa protein K04043 - - 0.0 1015.0
TH2_k127_3576396_1 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 306.0
TH2_k127_3576396_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000006897 215.0
TH2_k127_358397_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 7.047e-319 998.0
TH2_k127_358397_1 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000623 235.0
TH2_k127_3609465_0 domain protein - - - 0.00000000000000000000004947 106.0
TH2_k127_361377_0 Protoglobin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 409.0
TH2_k127_361377_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 321.0
TH2_k127_361377_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001507 294.0
TH2_k127_361377_3 acetyltransferase - - - 0.000000000000000000000000000000000003519 143.0
TH2_k127_361377_4 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000005632 115.0
TH2_k127_361377_5 Kinase-like K12132 - 2.7.11.1 0.00001257 56.0
TH2_k127_3619125_0 - - - - 1.198e-202 662.0
TH2_k127_3619125_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 407.0
TH2_k127_3619125_2 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 321.0
TH2_k127_3619125_3 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.00000000001493 79.0
TH2_k127_3623723_0 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001812 278.0
TH2_k127_3623723_1 Glycosyl transferase group 1 K12989 - - 0.000000000000000000000000000000000000000000000000000001289 196.0
TH2_k127_3623723_2 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000001586 172.0
TH2_k127_3640391_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 610.0
TH2_k127_3640391_2 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000009733 124.0
TH2_k127_3645265_0 Belongs to the argininosuccinate synthase family. Type K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 3.527e-219 685.0
TH2_k127_3645265_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 479.0
TH2_k127_36460_0 GAF domain - - - 0.000000000000000000000000000000000000000000000007896 193.0
TH2_k127_36460_1 von Willebrand factor (vWF) type A domain - - - 0.000000001144 72.0
TH2_k127_36460_2 amine dehydrogenase activity - - - 0.00000004191 66.0
TH2_k127_3648286_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 474.0
TH2_k127_3648286_1 Magnesium transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000001443 243.0
TH2_k127_3648286_2 CorA-like Mg2+ transporter protein - - - 0.00000000933 66.0
TH2_k127_3657920_0 DEAD/H associated K03724 - - 0.0 1340.0
TH2_k127_3668612_0 Heat shock 70 kDa protein K04043 - - 0.0 1021.0
TH2_k127_3668612_1 Large family of predicted nucleotide-binding domains K07175 - - 8.125e-231 728.0
TH2_k127_3668612_2 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 464.0
TH2_k127_3668612_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000044 231.0
TH2_k127_3668612_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K04760 - - 0.0000000000000000000000000000000000000000000000000000000005656 216.0
TH2_k127_3668612_5 Protein of unknown function (DUF493) K09158 - - 0.00000000000000000000000000000002115 128.0
TH2_k127_3668612_6 - - - - 0.00000001553 57.0
TH2_k127_3668612_7 MerR HTH family regulatory protein - - - 0.0000003431 52.0
TH2_k127_3668612_8 endoglucanase-related protein, glucosyl hydrolase family 9 protein - - - 0.00003666 56.0
TH2_k127_3696512_0 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 410.0
TH2_k127_3696512_1 nuclear chromosome segregation K01421,K02557 - - 0.00000000000000000000000000000000000000000000002336 186.0
TH2_k127_3696512_2 Kelch motif - - - 0.0000000000000000002026 103.0
TH2_k127_3696512_3 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000965 86.0
TH2_k127_3697704_0 FAD dependent oxidoreductase central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 372.0
TH2_k127_3710594_0 histone H2A K63-linked ubiquitination K08884,K11894 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 332.0
TH2_k127_3710594_1 TadE-like protein - - - 0.000000000000000000000000000007584 124.0
TH2_k127_3710594_2 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000001677 97.0
TH2_k127_371163_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 415.0
TH2_k127_371163_1 - - - - 0.00000000000000000001388 102.0
TH2_k127_371163_2 FHA domain - - - 0.000000001988 69.0
TH2_k127_371163_3 - - - - 0.000000004147 63.0
TH2_k127_3712018_0 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 295.0
TH2_k127_3712018_1 COG1233 Phytoene dehydrogenase and related proteins K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000009658 266.0
TH2_k127_3712018_2 COG1233 Phytoene dehydrogenase and related proteins K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000005635 199.0
TH2_k127_3712898_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 512.0
TH2_k127_3712898_1 - - - - 0.00000000001775 69.0
TH2_k127_3725204_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1301.0
TH2_k127_3725204_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000006431 194.0
TH2_k127_3725204_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000002486 56.0
TH2_k127_3738312_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003196 250.0
TH2_k127_3738312_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000001156 213.0
TH2_k127_3738312_2 PFAM PHA accumulation regulator DNA-binding protein - - - 0.000000000000000000000000000000000000001768 152.0
TH2_k127_37428_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 591.0
TH2_k127_37428_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 394.0
TH2_k127_37428_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 304.0
TH2_k127_37428_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000003246 229.0
TH2_k127_37428_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000002332 218.0
TH2_k127_37428_5 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000004325 183.0
TH2_k127_37428_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000001568 145.0
TH2_k127_37428_8 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000002142 74.0
TH2_k127_3751922_0 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 483.0
TH2_k127_3751922_1 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 441.0
TH2_k127_3751922_2 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 346.0
TH2_k127_3751922_3 GGDEF domain K21009 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004815 283.0
TH2_k127_3751922_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001292 274.0
TH2_k127_3755390_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 577.0
TH2_k127_3755390_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000003452 239.0
TH2_k127_3755390_2 Protein kinase domain - - - 0.0000000001046 63.0
TH2_k127_3755396_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 370.0
TH2_k127_3755396_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 321.0
TH2_k127_3755396_2 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 319.0
TH2_k127_3755396_3 B domain of TMEM189, localisation domain K20656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 310.0
TH2_k127_3755396_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002789 274.0
TH2_k127_3755396_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000001832 231.0
TH2_k127_3755396_6 Peptidase M50B-like - - - 0.000000000000000000000000000000000000000000000000000000000002703 217.0
TH2_k127_3755396_7 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000000000000000000000005563 214.0
TH2_k127_3755396_9 TonB family K03646,K03832 - - 0.00000000000000000000000000000000000000003923 165.0
TH2_k127_3771729_0 phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000958 265.0
TH2_k127_3771729_1 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000000000000000000000001631 208.0
TH2_k127_3775470_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 514.0
TH2_k127_3775470_1 Bacterial Ig-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001964 257.0
TH2_k127_3777190_0 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 581.0
TH2_k127_3777190_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 360.0
TH2_k127_3777190_2 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000002104 116.0
TH2_k127_3788416_0 Type III secretion protein K03230 - - 0.0 1135.0
TH2_k127_3788416_1 Tetratricopeptide repeat - - - 0.00000000000003687 80.0
TH2_k127_3797585_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 6.784e-275 859.0
TH2_k127_3797585_1 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 485.0
TH2_k127_3798432_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 351.0
TH2_k127_3799016_0 RNA polymerase recycling family C-terminal K03580 - - 1.706e-275 858.0
TH2_k127_3799016_1 Tryptophan halogenase K14257 - 1.14.19.49 0.0000000000000000000000000000000000000000000000000008196 190.0
TH2_k127_3799016_2 Phosphopantetheine attachment site K02078 - - 0.000000000000009071 79.0
TH2_k127_3800937_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 604.0
TH2_k127_3800937_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000002845 239.0
TH2_k127_3800937_2 iron ion homeostasis K04758 - - 0.000000001856 61.0
TH2_k127_3801991_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 319.0
TH2_k127_3801991_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000002681 261.0
TH2_k127_3801991_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000005898 217.0
TH2_k127_3801991_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000003419 153.0
TH2_k127_3806287_0 response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 527.0
TH2_k127_3808107_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1074.0
TH2_k127_3808107_1 peptidoglycan biosynthetic process - - - 0.000000000000000000000000000000000000007006 148.0
TH2_k127_3808107_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000003541 137.0
TH2_k127_3808384_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1341.0
TH2_k127_3808384_1 NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 481.0
TH2_k127_3808384_4 repeat protein - - - 0.000007034 51.0
TH2_k127_38086_0 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00207,K12527,K17723 - 1.3.1.1,1.3.1.2,1.97.1.9 3.007e-220 702.0
TH2_k127_38086_1 Pyridoxal-phosphate dependent enzyme K01738,K01912 - 2.5.1.47,6.2.1.30 6.369e-200 650.0
TH2_k127_38086_2 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 409.0
TH2_k127_38086_3 threonine synthase activity K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 379.0
TH2_k127_38086_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 329.0
TH2_k127_38086_5 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000225 123.0
TH2_k127_38086_6 - - - - 0.00000000000008104 78.0
TH2_k127_3815894_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 3.674e-280 869.0
TH2_k127_3815894_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000001496 162.0
TH2_k127_3817436_0 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009693 268.0
TH2_k127_3817436_1 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000004863 98.0
TH2_k127_3817436_2 Transcriptional regulator - - - 0.0002196 52.0
TH2_k127_3817436_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0008077 46.0
TH2_k127_3844348_0 Lamin Tail Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 360.0
TH2_k127_3844348_1 NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 338.0
TH2_k127_3847805_0 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 390.0
TH2_k127_3847805_1 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000108 119.0
TH2_k127_3847805_2 - - - - 0.00001016 52.0
TH2_k127_3849626_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 3.896e-304 949.0
TH2_k127_3849626_1 ABC-type transport system involved in lipoprotein release permease component K09808 - - 1.671e-270 857.0
TH2_k127_3849626_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 520.0
TH2_k127_3849626_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 360.0
TH2_k127_3849626_4 Histidine kinase K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 341.0
TH2_k127_3849626_5 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000003933 89.0
TH2_k127_3852131_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 430.0
TH2_k127_3852131_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 386.0
TH2_k127_3852131_2 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000006083 219.0
TH2_k127_3852131_3 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000000000000000000001608 157.0
TH2_k127_3854220_0 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002701 269.0
TH2_k127_3854220_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003791 273.0
TH2_k127_3854220_2 - - - - 0.0007132 48.0
TH2_k127_3859172_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 534.0
TH2_k127_3859172_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000002658 242.0
TH2_k127_3859172_2 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.000000000000000000000000000000000000000001587 159.0
TH2_k127_387271_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004232 254.0
TH2_k127_387271_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000001609 161.0
TH2_k127_3882852_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 1.814e-216 679.0
TH2_k127_3882852_1 response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 611.0
TH2_k127_3882852_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 539.0
TH2_k127_3882852_3 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 513.0
TH2_k127_3882852_4 Molybdenum Cofactor Synthesis C K03639 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000002095 224.0
TH2_k127_3882852_5 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000386 130.0
TH2_k127_388566_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 4.599e-227 715.0
TH2_k127_3890516_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2479.0
TH2_k127_3890516_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1938.0
TH2_k127_3890516_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000002102 170.0
TH2_k127_3891292_0 Large extracellular alpha-helical protein - - - 9.694e-274 856.0
TH2_k127_3891292_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 3.075e-204 651.0
TH2_k127_3891292_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 302.0
TH2_k127_3906068_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1103.0
TH2_k127_3906068_1 HEAT repeats - - - 0.000000000001177 74.0
TH2_k127_3909001_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000001101 216.0
TH2_k127_3909001_1 Ribbon-helix-helix domain - - - 0.00000000000009661 76.0
TH2_k127_3913611_0 benzoyl-CoA reductase K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 413.0
TH2_k127_3913611_1 benzoyl-CoA reductase K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 333.0
TH2_k127_3913611_2 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000009658 233.0
TH2_k127_3927585_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 465.0
TH2_k127_3927585_1 amine dehydrogenase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000002909 231.0
TH2_k127_3927585_2 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000001464 170.0
TH2_k127_3927585_3 - - - - 0.00000000000000000001745 107.0
TH2_k127_3930984_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.623e-300 937.0
TH2_k127_3930984_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000001028 161.0
TH2_k127_3934943_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 336.0
TH2_k127_3934943_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000186 195.0
TH2_k127_394211_0 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 612.0
TH2_k127_394211_1 skeletal muscle myosin thick filament assembly K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.0007402 52.0
TH2_k127_3943018_0 GMC oxidoreductase - - - 1.89e-276 857.0
TH2_k127_3943018_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003467 231.0
TH2_k127_3943018_3 Peptidase family M23 - - - 0.000000000000000000000000000000000000000131 165.0
TH2_k127_3943018_4 cell adhesion involved in biofilm formation K13735,K20276 - - 0.0000000000000000007611 94.0
TH2_k127_3944362_0 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 531.0
TH2_k127_3944362_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 335.0
TH2_k127_3944362_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 295.0
TH2_k127_3944362_3 COGs COG0659 Sulfate permease and related transporter (MFS superfamily) K03321 - - 0.000000000000000000000000000000000000000000000000000002528 196.0
TH2_k127_3944362_4 - - - - 0.0000000000262 71.0
TH2_k127_3944741_1 PFAM PEGA domain - - - 0.00008087 49.0
TH2_k127_396500_0 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000001751 229.0
TH2_k127_3984202_0 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006023 278.0
TH2_k127_3984202_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000007917 186.0
TH2_k127_3984202_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000001295 145.0
TH2_k127_398768_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.536e-236 739.0
TH2_k127_398768_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 3.103e-220 687.0
TH2_k127_398768_2 Belongs to the heat shock protein 70 family K04043 - - 6.945e-217 691.0
TH2_k127_3989262_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000003681 190.0
TH2_k127_3989262_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000003576 163.0
TH2_k127_3989262_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000008065 87.0
TH2_k127_3989262_3 Domain of unknown function (DUF4154) - - - 0.0004649 49.0
TH2_k127_399097_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.942e-234 734.0
TH2_k127_399097_2 Domains REC, HisKA, HATPase_c - - - 0.0000000000000000000000000000000000000000000000000000000000000000005204 241.0
TH2_k127_399097_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000001521 199.0
TH2_k127_399097_4 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000002215 101.0
TH2_k127_399097_5 DEAD DEAH box helicase - - - 0.0000000000000000003659 103.0
TH2_k127_399097_6 cheY-homologous receiver domain - - - 0.0000000000005261 77.0
TH2_k127_3995014_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 473.0
TH2_k127_3995014_1 HI0933-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 392.0
TH2_k127_3995014_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 384.0
TH2_k127_4004676_0 pseudouridine synthase activity K06176 - 5.4.99.27 3.362e-200 631.0
TH2_k127_4004676_1 Helix-turn-helix domain K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003769 249.0
TH2_k127_4004676_2 - - - - 0.000000000000000000000000000000000000000000000000002815 191.0
TH2_k127_4004676_3 Type ii and iii secretion system protein - - - 0.00000000005474 72.0
TH2_k127_4004676_4 - - - - 0.0000000004383 71.0
TH2_k127_4013108_0 peptidoglycan binding domain protein - - - 0.00000000000000000000000002807 122.0
TH2_k127_4013108_1 imidazolonepropionase K01468 - 3.5.2.7 0.000000000000000000004145 95.0
TH2_k127_4013108_2 Amidase - - - 0.00000000000000001165 83.0
TH2_k127_4014193_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000002244 152.0
TH2_k127_4014193_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000351 149.0
TH2_k127_402510_0 Domain of unknown function (DUF3369) - - - 0.00000000000000000000000000000000000000000000000000125 201.0
TH2_k127_4041209_0 PFAM FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 355.0
TH2_k127_4041209_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 325.0
TH2_k127_4041209_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000003888 174.0
TH2_k127_4052387_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 458.0
TH2_k127_4052387_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 409.0
TH2_k127_4052387_2 - - - - 0.0000000000000000000265 93.0
TH2_k127_4063346_0 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 493.0
TH2_k127_4063346_1 - - - - 0.00000000000000000000000000000000000006579 152.0
TH2_k127_4075743_0 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 449.0
TH2_k127_4075743_1 - - - - 0.0000000000000000000000000006395 119.0
TH2_k127_4080398_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 515.0
TH2_k127_4088621_0 heat shock protein binding - - - 1.522e-211 689.0
TH2_k127_4088621_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008039 284.0
TH2_k127_4089723_0 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 400.0
TH2_k127_4089723_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000006507 202.0
TH2_k127_4089723_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000009962 187.0
TH2_k127_4089723_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.000000000000000000000000000000000000000000000003594 181.0
TH2_k127_4089723_4 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000006502 111.0
TH2_k127_4089723_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000003888 91.0
TH2_k127_4089723_6 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000001219 71.0
TH2_k127_4095507_0 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 485.0
TH2_k127_4095507_1 Kelch motif K20285 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000008907 66.0
TH2_k127_4095507_2 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00219 - 1.3.1.34 0.0000005113 51.0
TH2_k127_4130458_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 454.0
TH2_k127_4130458_1 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 395.0
TH2_k127_4130458_2 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009867 252.0
TH2_k127_4130458_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001608 260.0
TH2_k127_4130458_4 OsmC-like protein K09136 - - 0.0000000000000000000000000000000000000001043 154.0
TH2_k127_4130458_5 FHA domain - - - 0.000000000000000000000000000001607 137.0
TH2_k127_4130458_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000004745 127.0
TH2_k127_4130458_7 protein secretion by the type VII secretion system K11904,K21493 - - 0.0000000000000000000004512 109.0
TH2_k127_4130707_0 PrkA serine protein kinase C-terminal domain - - - 0.0 1026.0
TH2_k127_4130707_2 AAA domain K01551 - 3.6.3.16 0.0000000000000000000000000000000000002288 147.0
TH2_k127_4134012_0 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 5.303e-293 912.0
TH2_k127_4134012_1 Major Facilitator Superfamily K02445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 483.0
TH2_k127_4134012_2 nUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000113 284.0
TH2_k127_4142954_0 Dehydrogenase K00076,K10780 - 1.1.1.159,1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 363.0
TH2_k127_4142954_1 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000005796 168.0
TH2_k127_4142954_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000001788 139.0
TH2_k127_4142954_3 RF-1 domain K15034 - - 0.000392 44.0
TH2_k127_4144168_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 563.0
TH2_k127_4144168_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008455 531.0
TH2_k127_4144168_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 391.0
TH2_k127_4144168_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 339.0
TH2_k127_414422_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 468.0
TH2_k127_414422_1 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000003436 209.0
TH2_k127_414422_2 chemotaxis K02659,K03408 - - 0.000000000000000000000000000000000000000144 169.0
TH2_k127_414422_3 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000003434 130.0
TH2_k127_414422_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000001673 129.0
TH2_k127_416828_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000003671 195.0
TH2_k127_416828_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000004047 151.0
TH2_k127_4175199_0 NAD binding K00333,K05579,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001324 288.0
TH2_k127_4175199_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000009291 183.0
TH2_k127_4175199_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330,K05574 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000001795 102.0
TH2_k127_4175199_3 protein kinase activity - - - 0.0001228 47.0
TH2_k127_4176528_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 464.0
TH2_k127_4176528_1 PFAM Ig domain protein, group 1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 398.0
TH2_k127_418301_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 2.192e-206 659.0
TH2_k127_418301_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 392.0
TH2_k127_418301_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 392.0
TH2_k127_418301_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000002912 239.0
TH2_k127_418301_4 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000003266 240.0
TH2_k127_418301_5 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000001055 201.0
TH2_k127_418301_6 Ribosomal protein S21 K02970 - - 0.00000000000000000000001334 100.0
TH2_k127_4192547_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1469.0
TH2_k127_4192547_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 552.0
TH2_k127_4193389_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.401e-261 832.0
TH2_k127_4193389_2 Transcriptional regulator - - - 0.00000000000000000000000000000004862 133.0
TH2_k127_4193389_3 Phosphate acyltransferases - - - 0.000000006787 58.0
TH2_k127_4197066_0 chorismate mutase domain of gram positive AroA protein K13853 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 381.0
TH2_k127_4197066_1 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 358.0
TH2_k127_4206526_0 A-macroglobulin receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 475.0
TH2_k127_420905_0 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 483.0
TH2_k127_420905_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 394.0
TH2_k127_420905_2 Carbon-nitrogen hydrolase K01431,K12251 - 3.5.1.53,3.5.1.6 0.00000000000000000000005263 110.0
TH2_k127_420905_3 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.000000003929 57.0
TH2_k127_4212892_0 negative regulation of transforming growth factor beta1 production K03068,K06261,K06593,K08867,K09187,K12488,K13738,K14972,K20050,K20371 GO:0000003,GO:0001654,GO:0001667,GO:0001745,GO:0002064,GO:0002065,GO:0002066,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005938,GO:0006928,GO:0006996,GO:0007010,GO:0007015,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007423,GO:0008150,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010564,GO:0010631,GO:0016020,GO:0016043,GO:0016477,GO:0017124,GO:0019904,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0030029,GO:0030036,GO:0030100,GO:0030154,GO:0030496,GO:0030707,GO:0030855,GO:0032153,GO:0032154,GO:0032155,GO:0032465,GO:0032501,GO:0032502,GO:0032504,GO:0032794,GO:0032879,GO:0034329,GO:0034330,GO:0034332,GO:0034333,GO:0040011,GO:0043062,GO:0043063,GO:0044085,GO:0044421,GO:0044424,GO:0044425,GO:0044444,GO:0044448,GO:0044459,GO:0044464,GO:0044703,GO:0045171,GO:0045177,GO:0045179,GO:0045216,GO:0045807,GO:0048259,GO:0048260,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048592,GO:0048609,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050794,GO:0050839,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051179,GO:0051302,GO:0051674,GO:0051704,GO:0051726,GO:0060429,GO:0060627,GO:0065007,GO:0071840,GO:0071944,GO:0090130,GO:0090132,GO:0090596,GO:0097435,GO:0098590,GO:0099568,GO:0099738 2.1.1.43,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 551.0
TH2_k127_4212892_1 domain, Protein K01212,K12287,K20276 - 3.2.1.65 0.0000000000000000000000000000000000000000000000000000000003855 232.0
TH2_k127_4219584_0 PQQ enzyme repeat K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 327.0
TH2_k127_4219584_1 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000179 281.0
TH2_k127_4219584_2 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000003233 201.0
TH2_k127_4219584_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000001572 184.0
TH2_k127_4219584_5 metal-dependent phosphohydrolase HD region K07814 - - 0.00000000000000361 89.0
TH2_k127_4222608_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 541.0
TH2_k127_4222608_1 histone H2A K63-linked ubiquitination K08884,K11894 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 490.0
TH2_k127_4222608_2 WYL domain K13572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 421.0
TH2_k127_4222608_3 WYL domain K13573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 363.0
TH2_k127_4240830_0 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 552.0
TH2_k127_4240830_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 455.0
TH2_k127_4240830_2 succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000001733 97.0
TH2_k127_4256566_0 - - - - 0.00000000000000000000000000000000000000000000000000000008996 200.0
TH2_k127_4256566_1 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000216 140.0
TH2_k127_4256566_2 - - - - 0.00000000000000000000000000004083 127.0
TH2_k127_4256566_3 Dienelactone hydrolase-like enzyme - - - 0.000001192 59.0
TH2_k127_4273051_0 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 458.0
TH2_k127_4273051_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 316.0
TH2_k127_4273051_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 310.0
TH2_k127_4273051_3 Chagasin family peptidase inhibitor I42 - - - 0.00000000000000000000000000000000000000000000000000001724 198.0
TH2_k127_4273996_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 496.0
TH2_k127_4273996_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001595 254.0
TH2_k127_4284251_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 420.0
TH2_k127_428501_0 cellulose binding - - - 0.00000000000000000001181 100.0
TH2_k127_4299543_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 479.0
TH2_k127_4299543_1 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.00000000000000004251 96.0
TH2_k127_4299543_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000003406 86.0
TH2_k127_4307547_0 FtsX-like permease family - - - 1.477e-244 773.0
TH2_k127_4307547_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 504.0
TH2_k127_4307547_2 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 358.0
TH2_k127_4308612_0 Molydopterin dinucleotide binding domain - - - 3.409e-261 818.0
TH2_k127_4308612_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003572 241.0
TH2_k127_4308612_2 Catalyzes the conversion of acetoacetate to acetone and carbon dioxide K01574 - 4.1.1.4 0.000000000000000000000000000000000000000000002386 177.0
TH2_k127_4308612_3 transcriptional regulator - - - 0.00000000000000000000000000000000000000004155 163.0
TH2_k127_4312951_0 Lipopolysaccharide kinase (Kdo/WaaP) family K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 396.0
TH2_k127_4312951_1 AAA ATPase domain - - - 0.0000000000000000000000000000003065 137.0
TH2_k127_4321555_0 Domain of unknown function (DUF1508) K09946 GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000003217 97.0
TH2_k127_4321555_1 Domain of unknown function (DUF1508) K09946 - - 0.00000000000000001027 96.0
TH2_k127_4321555_2 FAD dependent oxidoreductase K09879 - - 0.000000000000001722 91.0
TH2_k127_4321555_3 PHP domain protein - - - 0.00000000002296 74.0
TH2_k127_4323740_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 597.0
TH2_k127_4323740_1 PFAM Cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000013 208.0
TH2_k127_4336014_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 320.0
TH2_k127_4336014_1 cellulose binding - - - 0.000000000000000000000000000000000000000006315 178.0
TH2_k127_4352380_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 387.0
TH2_k127_4352380_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 381.0
TH2_k127_4355553_0 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 462.0
TH2_k127_4355553_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000789 250.0
TH2_k127_4355553_2 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000001396 151.0
TH2_k127_4355553_3 PilZ domain - - - 0.000000000000000000000000001381 123.0
TH2_k127_4360622_0 PFAM Multi antimicrobial extrusion protein MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 551.0
TH2_k127_4360622_1 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000001604 171.0
TH2_k127_4360622_2 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000001112 132.0
TH2_k127_4360948_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002017 305.0
TH2_k127_4360948_1 GAF domain - - - 0.00000000000000000000000000000000000000000000000000002005 194.0
TH2_k127_4360948_2 guanyl-nucleotide exchange factor activity K02034 - - 0.000000000000000000000000000000000000000000007831 186.0
TH2_k127_4360948_3 metallopeptidase activity K01179,K07004,K12548 - 3.2.1.4 0.000000000000000001332 102.0
TH2_k127_4377827_0 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 434.0
TH2_k127_4377827_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 297.0
TH2_k127_4377827_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000001458 126.0
TH2_k127_4393528_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002683 279.0
TH2_k127_4393528_1 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000033 294.0
TH2_k127_4393528_2 lipopolysaccharide-transporting ATPase activity K07091,K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009655 274.0
TH2_k127_4404582_0 Leucyl-tRNA synthetase, Domain 2 K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1292.0
TH2_k127_4404582_1 Bacterial SH3 domain homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001119 266.0
TH2_k127_4404582_2 Lipopolysaccharide-assembly - - - 0.00000000000000000000002832 115.0
TH2_k127_4416268_0 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 607.0
TH2_k127_4416268_1 DNA methylase K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 440.0
TH2_k127_4416268_2 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 361.0
TH2_k127_4416268_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000001212 229.0
TH2_k127_4416268_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000001505 196.0
TH2_k127_4416268_5 50S ribosomal protein L31 K02909 - - 0.000000000000000000000000000000001036 134.0
TH2_k127_4421006_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 4.575e-194 612.0
TH2_k127_4421006_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 529.0
TH2_k127_4421006_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000003881 187.0
TH2_k127_4426933_0 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 552.0
TH2_k127_4426933_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 299.0
TH2_k127_4426933_2 Outer membrane efflux protein - - - 0.00006285 51.0
TH2_k127_4429685_0 Sel1-like repeats. K07126 - - 0.00000000000000000000000002834 123.0
TH2_k127_4446331_0 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 305.0
TH2_k127_4446331_1 Glycosyltransferase family 28 N-terminal domain K05841 - 2.4.1.173 0.000000000000000000000000000000000000000000000000000000000000000004115 238.0
TH2_k127_4446331_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000005325 115.0
TH2_k127_4454970_0 protein domain associated with - - - 0.00000000000000000000000000000000000000000000000000001432 195.0
TH2_k127_4454970_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 GO:0003674,GO:0003824,GO:0008119,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008757,GO:0010035,GO:0010038,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0046690,GO:0050896 2.1.1.67 0.0000000000000000000000004527 115.0
TH2_k127_4454970_2 - - - - 0.000000000003136 79.0
TH2_k127_4454970_3 - - - - 0.0001305 53.0
TH2_k127_4454970_4 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.000213 46.0
TH2_k127_446579_0 peptide catabolic process K13722 - - 0.00000000000000000000000000000000000000000000000000000000006002 229.0
TH2_k127_4470104_0 aminopeptidase N - - - 2.73e-221 700.0
TH2_k127_4470104_1 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006228 275.0
TH2_k127_448366_0 Amidase - - - 4.69e-208 668.0
TH2_k127_4502566_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.0 1900.0
TH2_k127_4502566_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000001213 230.0
TH2_k127_4502566_2 transcriptional regulator - - - 0.0000000000003103 76.0
TH2_k127_4515752_0 aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000002018 186.0
TH2_k127_4515752_1 dioxygenase K00464 - 1.13.11.75 0.0000000000000000000000000000000000000000001375 178.0
TH2_k127_4539898_0 peptidase K04774 GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0016020,GO:0019538,GO:0043170,GO:0044238,GO:0044464,GO:0071704,GO:0071944,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 329.0
TH2_k127_4539898_1 Peptidase M66 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 321.0
TH2_k127_4539898_2 Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000113 91.0
TH2_k127_4544407_0 Alpha-2-Macroglobulin K06894 - - 0.0 1090.0
TH2_k127_4544407_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 600.0
TH2_k127_454447_0 radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 303.0
TH2_k127_454447_1 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000002086 188.0
TH2_k127_454736_0 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 385.0
TH2_k127_454736_1 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000000000004054 175.0
TH2_k127_454736_2 LexA-binding, inner membrane-associated putative hydrolase K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000005522 101.0
TH2_k127_4547609_0 PFAM Endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000001436 157.0
TH2_k127_4547609_1 PFAM Ethanolamine ammonia lyase large subunit K03735 - 4.3.1.7 0.0000000000000000000000000000172 120.0
TH2_k127_4550418_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000321 57.0
TH2_k127_4556793_0 PFAM Radical SAM K06139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 544.0
TH2_k127_4556793_1 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 414.0
TH2_k127_4556793_2 Zn-dependent proteases and their inactivated homologs K03592 - - 0.00000000000000000000000000000000028 132.0
TH2_k127_4556793_3 lactoylglutathione lyase activity - - - 0.000001286 62.0
TH2_k127_4569656_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 511.0
TH2_k127_4569656_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 368.0
TH2_k127_4569656_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 343.0
TH2_k127_4569656_3 RDD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001535 252.0
TH2_k127_4569656_4 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000132 201.0
TH2_k127_4569656_5 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000007608 174.0
TH2_k127_4569656_6 HEAT repeats - - - 0.00000000000000000000000004131 122.0
TH2_k127_4569656_7 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000006187 108.0
TH2_k127_4573062_0 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 401.0
TH2_k127_4597944_0 PBS lyase HEAT-like repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 463.0
TH2_k127_4597944_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 435.0
TH2_k127_4597944_2 LETM1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 355.0
TH2_k127_4597944_3 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000008252 227.0
TH2_k127_4598931_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 329.0
TH2_k127_4598931_1 amino acid K03294,K16238 - - 0.000000000000000000000000000000000000000000000000000000000000000000004231 250.0
TH2_k127_4599584_0 response regulator K07713 - - 5.192e-203 642.0
TH2_k127_4599584_1 Selenocysteine-specific translation elongation factor K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 301.0
TH2_k127_4599780_0 Late embryogenesis abundant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003427 277.0
TH2_k127_4599780_1 Aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 0.00000000000000000000000000000000000000000000000000003235 193.0
TH2_k127_4602050_0 PFAM adenosine AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000004976 195.0
TH2_k127_4602050_1 Forkhead associated domain - - - 0.0000000000000000000000000000000000000003573 170.0
TH2_k127_4602050_2 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.000000000000001929 82.0
TH2_k127_4606609_0 Alpha-amylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 606.0
TH2_k127_4608189_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 9.622e-305 946.0
TH2_k127_4608189_1 SpoVR like protein K06415 - - 3.247e-290 897.0
TH2_k127_4608189_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 447.0
TH2_k127_4635967_0 oligopeptide transporter, OPT family - - - 6.545e-249 790.0
TH2_k127_4635967_1 lyase activity - - - 5.162e-205 681.0
TH2_k127_4635967_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 4.008e-196 647.0
TH2_k127_4635967_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 345.0
TH2_k127_4635967_4 - - - - 0.000000000000000000000000000000004145 130.0
TH2_k127_4635967_5 Helix-turn-helix domain - - - 0.0000000000000000000000000006725 114.0
TH2_k127_4643329_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 400.0
TH2_k127_4643329_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000001123 125.0
TH2_k127_4644147_0 ATP-dependent metalloprotease, FtsH K03798 - - 3.932e-290 916.0
TH2_k127_4644147_1 - - - - 0.000000000000000000000000000000000000004335 152.0
TH2_k127_4644147_2 - - - - 0.000000000000000000004952 94.0
TH2_k127_4665737_0 Peptidase S46 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 431.0
TH2_k127_4665737_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000004813 147.0
TH2_k127_4667246_0 Acts as a magnesium transporter K06213 - - 5.072e-195 617.0
TH2_k127_4667246_1 - - - - 0.000000000000000000000000000000000000001381 150.0
TH2_k127_4667246_2 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000008284 160.0
TH2_k127_4667246_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000001448 111.0
TH2_k127_4672881_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007952 491.0
TH2_k127_4673672_0 Diguanylate cyclase, GGDEF domain - - - 0.0 1320.0
TH2_k127_4673672_1 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 468.0
TH2_k127_4673672_2 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 312.0
TH2_k127_4673672_3 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000001066 228.0
TH2_k127_4673672_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000771 204.0
TH2_k127_4678335_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1013.0
TH2_k127_4678335_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.948e-241 763.0
TH2_k127_4678335_2 PAC sensor-containing diguanylate cyclase phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 557.0
TH2_k127_4678335_3 Protein of unknown function (DUF507) K09804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 295.0
TH2_k127_4678335_4 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007123 288.0
TH2_k127_4678335_5 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000026 243.0
TH2_k127_4678335_6 - - - - 0.0000000000000000000000000446 114.0
TH2_k127_4688524_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 340.0
TH2_k127_4688524_1 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.00000000000000000000005749 102.0
TH2_k127_4688898_0 Belongs to the glycosyl hydrolase 18 family K01183 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008061,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009653,GO:0009987,GO:0016740,GO:0016757,GO:0016787,GO:0016798,GO:0017144,GO:0030154,GO:0030435,GO:0032502,GO:0042737,GO:0043170,GO:0043934,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046348,GO:0048646,GO:0048856,GO:0048869,GO:0071704,GO:0097367,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.2.1.14 0.000000003519 70.0
TH2_k127_4692081_0 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004558 241.0
TH2_k127_4697824_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000001762 182.0
TH2_k127_4697824_2 HupE / UreJ protein - - - 0.0000000000008714 73.0
TH2_k127_4710083_0 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 424.0
TH2_k127_4710083_1 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 304.0
TH2_k127_4710083_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000004935 164.0
TH2_k127_4710083_4 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000000000001903 129.0
TH2_k127_4710083_5 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000000000000001122 124.0
TH2_k127_4710083_6 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000003986 93.0
TH2_k127_4715719_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1009.0
TH2_k127_4715719_1 ATPase involved in DNA repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 410.0
TH2_k127_4715719_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 289.0
TH2_k127_4715719_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000001614 250.0
TH2_k127_4715719_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000001413 180.0
TH2_k127_4715719_5 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000003493 122.0
TH2_k127_4715719_6 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.00000000000005891 75.0
TH2_k127_4718501_0 Fungalysin metallopeptidase (M36) - - - 2.522e-302 963.0
TH2_k127_4728237_0 - - - - 0.000000000000000000000000000000000000000000000000000000422 208.0
TH2_k127_4728237_1 NUDIX domain - - - 0.00000000000000000000000000000000000001298 146.0
TH2_k127_4728237_2 WD40 repeats - - - 0.00000000004645 68.0
TH2_k127_473450_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 473.0
TH2_k127_473450_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 334.0
TH2_k127_473450_2 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.00000001412 60.0
TH2_k127_4742299_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 1.02e-240 763.0
TH2_k127_4742299_1 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 295.0
TH2_k127_4742299_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001373 256.0
TH2_k127_4742299_3 Haloacid dehalogenase-like hydrolase K07025,K20866 - 3.1.3.10 0.000000000000000000000000000000000000000000000000000004309 207.0
TH2_k127_4766669_0 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 5.981e-204 646.0
TH2_k127_4766669_1 S4 RNA-binding domain K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 492.0
TH2_k127_4766669_2 protein homooligomerization K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 304.0
TH2_k127_4768995_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.211e-248 779.0
TH2_k127_4768995_1 Major Facilitator Superfamily K07783 - - 0.00000000006455 65.0
TH2_k127_4790302_0 PFAM Glycosyl transferase, group 1 - - - 6.431e-268 842.0
TH2_k127_4790302_1 beta-1,4-mannooligosaccharide phosphorylase - - - 0.00000000000000000000000000006991 119.0
TH2_k127_4799442_0 Belongs to the HpcH HpaI aldolase family K01644,K08691 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 314.0
TH2_k127_4799442_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000339 220.0
TH2_k127_4803638_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 535.0
TH2_k127_4803638_1 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 418.0
TH2_k127_4803638_2 transmembrane transport K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 340.0
TH2_k127_4803638_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000004804 159.0
TH2_k127_4803638_4 Bacterial PH domain K08981 - - 0.000000000000000000000000000000001088 144.0
TH2_k127_4803638_5 Bacterial PH domain - - - 0.000000000000000000000000000000002253 144.0
TH2_k127_4803638_6 protein kinase activity - - - 0.0000000000000000002179 103.0
TH2_k127_481108_0 MacB-like periplasmic core domain K02004 - - 0.0 1019.0
TH2_k127_481108_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000003009 201.0
TH2_k127_481108_2 cheY-homologous receiver domain K07657 - - 0.000000000000000000000000000000000000000000000000000001205 198.0
TH2_k127_4813497_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 3.852e-194 610.0
TH2_k127_4813497_1 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 484.0
TH2_k127_4813497_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 340.0
TH2_k127_4813497_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001027 271.0
TH2_k127_4813497_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000004053 275.0
TH2_k127_4813497_5 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000003027 195.0
TH2_k127_4813497_6 - - - - 0.0000000000000000000000000000000000000000000000006392 198.0
TH2_k127_4813497_7 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03767 - 5.2.1.8 0.0000000000000000004301 98.0
TH2_k127_4816254_0 guanosine tetraphosphate metabolic process - - - 0.000000000000000000000000000000000004306 145.0
TH2_k127_483740_0 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 586.0
TH2_k127_483740_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000008332 216.0
TH2_k127_483740_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000001676 209.0
TH2_k127_483740_3 HEAT repeats - - - 0.00000000000000004277 86.0
TH2_k127_4837634_0 Carboxypeptidase regulatory-like domain - - - 1.608e-257 824.0
TH2_k127_4837634_1 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000009949 252.0
TH2_k127_4837634_2 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000004743 114.0
TH2_k127_484105_0 Gaf domain K01768,K02283,K10851,K21685 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 591.0
TH2_k127_484105_1 COG0044 Dihydroorotase and related cyclic amidohydrolases K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 529.0
TH2_k127_484105_2 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 386.0
TH2_k127_484105_3 PFAM regulatory protein, ArsR K21903 - - 0.00000000000000001518 83.0
TH2_k127_4843245_0 Tetratricopeptide repeat - - - 0.00000000000000000002903 98.0
TH2_k127_4843245_1 Belongs to the pseudouridine synthase RluA family K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00002135 48.0
TH2_k127_4868052_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002492 248.0
TH2_k127_4868052_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000001664 63.0
TH2_k127_4876721_0 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 537.0
TH2_k127_4876721_1 glutamate:sodium symporter activity K03312 GO:0003333,GO:0003674,GO:0005215,GO:0005283,GO:0005310,GO:0005342,GO:0005343,GO:0005416,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006835,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015081,GO:0015171,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015501,GO:0015672,GO:0015711,GO:0015849,GO:0016020,GO:0017153,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0044464,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000001286 213.0
TH2_k127_4881671_0 trisaccharide binding K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 352.0
TH2_k127_4881671_1 peptidyl-tyrosine sulfation - - - 0.00000000000001908 85.0
TH2_k127_4882866_0 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 379.0
TH2_k127_4882866_1 - - - - 0.000000000000000000000000000000000000000000000000000000000004122 216.0
TH2_k127_4882866_2 COG1668 ABC-type Na efflux pump, permease component K01992,K09696 - - 0.000000000000000000000000000000000008605 152.0
TH2_k127_4889138_0 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000001006 91.0
TH2_k127_4889138_1 Bacterial Ig-like domain (group 3) - - - 0.00000000007644 76.0
TH2_k127_4889138_2 COG4326 Sporulation control protein K06377 - - 0.00000562 59.0
TH2_k127_4889138_3 repeat-containing protein - - - 0.000009802 58.0
TH2_k127_4889539_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 600.0
TH2_k127_4889539_1 Carbon-nitrogen hydrolase K01431,K12251 - 3.5.1.53,3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 471.0
TH2_k127_4889539_2 Amidohydrolase family K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 449.0
TH2_k127_4889539_3 AMIN domain - - - 0.00000000000000000000000000000003666 138.0
TH2_k127_4898249_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1286.0
TH2_k127_4898249_2 - - - - 0.0000000000000000000000000000001296 140.0
TH2_k127_4898249_3 TadE-like protein - - - 0.000000000000000000000000000001248 123.0
TH2_k127_4898249_4 - - - - 0.00000000000000000000000000002769 128.0
TH2_k127_4898249_5 - - - - 0.00000003486 66.0
TH2_k127_4905871_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000001666 242.0
TH2_k127_4905871_1 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000000000000000000000000000006826 221.0
TH2_k127_4905871_2 light absorption - - - 0.00000000000000000000000000000000000000000000001404 174.0
TH2_k127_4918062_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 327.0
TH2_k127_4918062_1 Peptidase family M48 - - - 0.0000000000000000005524 102.0
TH2_k127_4947546_0 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 302.0
TH2_k127_4947546_1 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000735 235.0
TH2_k127_495588_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 434.0
TH2_k127_495588_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000002447 222.0
TH2_k127_495588_2 reductase chain B K07307 - - 0.000000000000000000000000000000000006618 145.0
TH2_k127_495588_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0003561 48.0
TH2_k127_4961079_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 1.952e-211 672.0
TH2_k127_4970186_0 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 507.0
TH2_k127_4970186_1 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000004918 69.0
TH2_k127_4973640_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 6.768e-194 628.0
TH2_k127_4973640_1 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000001277 195.0
TH2_k127_4973640_2 NLP P60 protein - - - 0.0000000000000000000000000000005066 125.0
TH2_k127_4973640_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000005532 120.0
TH2_k127_4977081_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.677e-223 701.0
TH2_k127_4977081_1 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 362.0
TH2_k127_4977081_2 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001616 242.0
TH2_k127_4979136_0 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000032 269.0
TH2_k127_4979136_1 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000001285 193.0
TH2_k127_498144_0 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 422.0
TH2_k127_498144_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 409.0
TH2_k127_498144_2 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 290.0
TH2_k127_498144_3 protein, Hemolysin III K11068 - - 0.000000000000000000000000000000000000000000000000000000000001054 216.0
TH2_k127_498144_4 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000002404 213.0
TH2_k127_498144_5 Domain of unknown function (DU1801) - - - 0.00000002417 62.0
TH2_k127_499303_0 Oxygen tolerance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 481.0
TH2_k127_4997924_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 1.821e-288 895.0
TH2_k127_4997924_1 Peptidase family S58 K01266 - 3.4.11.19 5.56e-200 629.0
TH2_k127_5004467_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 350.0
TH2_k127_5004467_1 Alginate export - - - 0.000000000000000000000000000000000233 148.0
TH2_k127_5006926_0 Collagen triple helix repeat (20 copies) - - - 0.0000000000000486 87.0
TH2_k127_5006926_1 domain, Protein - - - 0.000000000003008 81.0
TH2_k127_5006926_2 amine dehydrogenase activity - - - 0.0000006704 57.0
TH2_k127_5006926_3 cell adhesion involved in biofilm formation - - - 0.000001866 59.0
TH2_k127_5006926_4 Hep Hag repeat protein K09942,K21449 - - 0.000004875 61.0
TH2_k127_5006926_7 Chaperone of endosialidase K21449 - - 0.0009045 53.0
TH2_k127_5014432_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 317.0
TH2_k127_5014432_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001309 251.0
TH2_k127_5014432_2 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000009083 132.0
TH2_k127_501659_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 377.0
TH2_k127_501659_1 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 355.0
TH2_k127_5066413_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 326.0
TH2_k127_5066413_1 PFAM FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000001401 226.0
TH2_k127_5070138_0 Pectate lyase superfamily protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 476.0
TH2_k127_5070138_1 - - - - 0.000000000000000000000000000000000000000000000000009006 190.0
TH2_k127_5079010_0 Vi polysaccharide biosynthesis protein vipB tviC K02473 - 5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 437.0
TH2_k127_5079010_1 Protein of unknown function (DUF2846) - - - 0.0000025 55.0
TH2_k127_5104072_0 DNA topoisomerase K02470,K02622 - 5.99.1.3 0.0 1024.0
TH2_k127_5104072_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 411.0
TH2_k127_5104072_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 418.0
TH2_k127_5104072_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 338.0
TH2_k127_5104072_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003374 251.0
TH2_k127_5104072_5 topoisomerase K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000001864 218.0
TH2_k127_5104072_6 Beta-galactosidase K05991 - 3.2.1.123 0.0000000000000000000000000000000000000000000000000000000000002164 231.0
TH2_k127_5104072_7 - - - - 0.00000000000003877 74.0
TH2_k127_5120722_0 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 584.0
TH2_k127_5120722_1 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 447.0
TH2_k127_5120722_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 359.0
TH2_k127_5120722_3 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000003338 200.0
TH2_k127_5120722_4 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000002583 159.0
TH2_k127_5130348_0 TadE-like protein - - - 0.00000000000000000000000000000000000000000000000000000007201 204.0
TH2_k127_5130348_1 radical SAM domain protein - - - 0.000000000000000000000003311 114.0
TH2_k127_5130348_2 PFAM TadE family protein - - - 0.000000000000545 83.0
TH2_k127_5133173_0 FGGY family of carbohydrate kinases, C-terminal domain K04043 - - 4.091e-215 686.0
TH2_k127_5133173_1 protein kinase activity - - - 0.00000000000000000000000000000000000000003107 156.0
TH2_k127_5133173_2 lyase activity - - - 0.000000000000000000000004509 106.0
TH2_k127_5144857_0 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 433.0
TH2_k127_5144857_1 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000001332 236.0
TH2_k127_5181565_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1109.0
TH2_k127_5181565_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 297.0
TH2_k127_5181565_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004381 301.0
TH2_k127_5191698_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 447.0
TH2_k127_5191698_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000001921 131.0
TH2_k127_5191698_5 thiamine biosynthesis protein ThiS K03154 - - 0.00000000000003623 80.0
TH2_k127_5191698_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000005606 76.0
TH2_k127_5193816_2 PFAM AsmA family protein K07289,K07290 - - 0.0004933 52.0
TH2_k127_5196917_0 aminopeptidase N K01263 - 3.4.11.14 5.136e-221 723.0
TH2_k127_5196917_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000002837 175.0
TH2_k127_5196917_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000843 190.0
TH2_k127_5196917_3 PAP2 superfamily - - - 0.000000000000000000002251 101.0
TH2_k127_5204579_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 293.0
TH2_k127_5204579_1 polysaccharide deacetylase - - - 0.000000000000003766 78.0
TH2_k127_521227_0 Type II/IV secretion system protein K02454 - - 2.969e-263 826.0
TH2_k127_521227_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000001767 170.0
TH2_k127_521227_3 - - - - 0.0000000000000000000002137 103.0
TH2_k127_5216413_0 N-6 DNA Methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 440.0
TH2_k127_5216413_1 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000009595 179.0
TH2_k127_5216413_2 - - - - 0.00000000000000000000000000000000000000001411 163.0
TH2_k127_5216413_3 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000005369 109.0
TH2_k127_5223315_0 COG3005 Nitrate TMAO reductases, membrane-bound tetraheme cytochrome c subunit K02569 - - 0.0000000000000000000000001192 121.0
TH2_k127_5223315_1 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.0000002489 64.0
TH2_k127_5242518_0 Surface antigen K07277 - - 1.845e-199 648.0
TH2_k127_5242518_1 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 455.0
TH2_k127_5242518_2 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 432.0
TH2_k127_5242518_3 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001182 275.0
TH2_k127_524503_1 PEGA domain - - - 0.00003947 48.0
TH2_k127_5246514_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000765 229.0
TH2_k127_5246514_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000001889 213.0
TH2_k127_5246514_2 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000004042 138.0
TH2_k127_5246514_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000003043 59.0
TH2_k127_5253560_0 GMC oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000008484 238.0
TH2_k127_5253560_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000004392 163.0
TH2_k127_5253560_2 Belongs to the ompA family K03286 - - 0.000000001221 63.0
TH2_k127_5267909_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.116e-307 972.0
TH2_k127_5267909_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000342 289.0
TH2_k127_5267909_2 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000000000000000000000000000002244 203.0
TH2_k127_5267909_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000003896 113.0
TH2_k127_5267909_4 Transporter associated domain K03699 - - 0.0000000002673 68.0
TH2_k127_5268998_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 6.284e-243 764.0
TH2_k127_5268998_1 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004012 265.0
TH2_k127_5268998_2 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000000000000000000000000002093 244.0
TH2_k127_5268998_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000003759 216.0
TH2_k127_5268998_4 STAS domain - - - 0.000000000000000000000000895 112.0
TH2_k127_5268998_5 - - - - 0.0000000000001339 80.0
TH2_k127_5285632_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 366.0
TH2_k127_5285632_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 369.0
TH2_k127_5285687_0 OPT oligopeptide transporter protein - - - 1.938e-263 825.0
TH2_k127_5285687_1 Putative bacterial sensory transduction regulator - - - 0.0004091 53.0
TH2_k127_5292688_0 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 448.0
TH2_k127_5292688_1 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 349.0
TH2_k127_5292688_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 318.0
TH2_k127_5292688_3 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000000000000000000000000000000000001116 229.0
TH2_k127_5302810_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 477.0
TH2_k127_5311420_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 6.312e-286 893.0
TH2_k127_5311420_1 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 539.0
TH2_k127_5311420_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620,K00930 - 2.3.1.1,2.3.1.35,2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 336.0
TH2_k127_5311420_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 326.0
TH2_k127_5311420_4 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000000004595 121.0
TH2_k127_5321590_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 601.0
TH2_k127_5321590_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 379.0
TH2_k127_5321590_2 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 328.0
TH2_k127_5321590_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 323.0
TH2_k127_5321590_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000001201 231.0
TH2_k127_5321590_5 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000006368 162.0
TH2_k127_5363007_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 5.4e-226 705.0
TH2_k127_5363007_1 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 460.0
TH2_k127_5363007_2 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 336.0
TH2_k127_5363007_3 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000001692 182.0
TH2_k127_5369883_0 Sugar transferase K03606 - - 7.104e-198 630.0
TH2_k127_5369883_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 453.0
TH2_k127_5369883_2 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.0000009454 51.0
TH2_k127_5373635_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 360.0
TH2_k127_5375949_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 395.0
TH2_k127_5375949_1 Calcineurin-like phosphoesterase K07099 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 354.0
TH2_k127_5375949_2 Protein of unknown function (DUF559) - - - 0.000000000000000000000000007104 121.0
TH2_k127_5397294_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007411 285.0
TH2_k127_54044_0 PFAM FecR protein - - - 0.000000000001124 82.0
TH2_k127_54044_1 PFAM FecR protein - - - 0.00000001288 66.0
TH2_k127_540501_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006457 265.0
TH2_k127_540501_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000005647 137.0
TH2_k127_541333_0 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 465.0
TH2_k127_541333_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 421.0
TH2_k127_541333_2 PFAM YdjC family protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003915 293.0
TH2_k127_541333_3 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000006354 105.0
TH2_k127_5414605_0 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000002255 230.0
TH2_k127_5414605_1 Belongs to the DsbB family K03611 - - 0.00000000000000000000000000000000000000004473 155.0
TH2_k127_5414605_2 Inorganic pyrophosphatase K15986 - 3.6.1.1 0.000000000000000000000000000003099 123.0
TH2_k127_541527_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 372.0
TH2_k127_541527_1 Methyltransferase small domain K15460 - 2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000216 282.0
TH2_k127_541527_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000004272 115.0
TH2_k127_541527_3 Transport permease protein K01992 - - 0.0004725 51.0
TH2_k127_5430264_0 Sterol desaturase - - - 1.342e-202 637.0
TH2_k127_5430264_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009321 261.0
TH2_k127_5430264_2 iron ion binding - - - 0.0000000000000000000000000000004181 134.0
TH2_k127_5430264_3 heat shock protein binding - - - 0.000001735 60.0
TH2_k127_5430264_4 cellulose binding - - - 0.000005109 55.0
TH2_k127_5462465_0 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 455.0
TH2_k127_5462465_1 Transcription factor zinc-finger - - - 0.000000000000000000000000000000004173 132.0
TH2_k127_5462465_2 Flavodoxin - - - 0.000000000000000000000000000003829 134.0
TH2_k127_5462465_3 domain protein - - - 0.000000000000000000000006484 107.0
TH2_k127_5466455_0 - - - - 0.0000000000000000000000905 108.0
TH2_k127_5466455_1 - - - - 0.0000000000000025 82.0
TH2_k127_5466455_2 - - - - 0.000000001915 61.0
TH2_k127_5466455_3 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.00000002322 58.0
TH2_k127_5470086_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 355.0
TH2_k127_5470086_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003217 277.0
TH2_k127_5470086_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000003614 146.0
TH2_k127_5470086_3 - - - - 0.00000000005491 68.0
TH2_k127_5490036_0 Lamin Tail Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 352.0
TH2_k127_5490036_1 transcriptional regulator - - - 0.000000000000000000000000000002928 123.0
TH2_k127_5519579_0 PFAM Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 499.0
TH2_k127_5519579_1 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.000000000000000000000000000107 128.0
TH2_k127_5519579_2 Putative regulatory protein - - - 0.000000009342 63.0
TH2_k127_5534124_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 347.0
TH2_k127_5534124_1 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000002161 246.0
TH2_k127_5557508_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 592.0
TH2_k127_5557508_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 387.0
TH2_k127_5557508_2 - - - - 0.00000000000000000000000000000009732 144.0
TH2_k127_5557508_3 Belongs to the peptidase S8 family - - - 0.0007647 44.0
TH2_k127_5573704_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1086.0
TH2_k127_5573704_1 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 605.0
TH2_k127_5573704_2 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 595.0
TH2_k127_5573704_3 PhoD-like phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000002995 132.0
TH2_k127_5573704_4 PilZ domain - - - 0.0000000000000000000000004361 113.0
TH2_k127_558770_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.129e-286 891.0
TH2_k127_558770_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 538.0
TH2_k127_558770_2 diguanylate cyclase activity - - - 0.0000000000000000000000003165 120.0
TH2_k127_558770_3 TatD related DNase K07051 - - 0.000000000000000000246 97.0
TH2_k127_5599881_0 PEGA domain K02014 - - 1.319e-312 986.0
TH2_k127_5599881_1 Methyltransferase FkbM domain - - - 0.00000000000000000000000000001502 127.0
TH2_k127_5613652_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 3.569e-258 802.0
TH2_k127_5613652_1 peptidase activity, acting on L-amino acid peptides K20276 - - 0.000000000125 74.0
TH2_k127_5626010_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 2.19e-226 714.0
TH2_k127_5626010_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000003898 250.0
TH2_k127_5629739_0 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 381.0
TH2_k127_5629739_1 - - - - 0.000000000000002147 80.0
TH2_k127_5640114_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 477.0
TH2_k127_5640114_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 404.0
TH2_k127_5640114_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006345 269.0
TH2_k127_5640114_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002483 258.0
TH2_k127_5640114_4 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000303 251.0
TH2_k127_564878_0 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 322.0
TH2_k127_5652786_0 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000002097 154.0
TH2_k127_5652786_1 - - - - 0.0009785 52.0
TH2_k127_566380_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000001398 224.0
TH2_k127_566380_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891,K15546 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000002884 194.0
TH2_k127_566380_2 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 0.000000000000000000000009775 106.0
TH2_k127_5665930_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000006614 240.0
TH2_k127_5665930_1 methyltransferase activity K00213,K00222 - 1.3.1.21,1.3.1.70 0.000000000000000000001003 99.0
TH2_k127_5665961_0 PFAM membrane bound O-acyl transferase MBOAT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 477.0
TH2_k127_569124_0 Tetratricopeptide repeat - - - 6.447e-203 656.0
TH2_k127_569124_1 - - - - 0.000000000000000000000000000000000000000000000000000000000007724 215.0
TH2_k127_569124_2 photosynthesis K12132,K20543 - 2.7.11.1 0.0002118 53.0
TH2_k127_5704862_0 Forkhead associated domain - - - 1.476e-204 644.0
TH2_k127_5704862_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000001479 200.0
TH2_k127_5704862_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000003154 152.0
TH2_k127_5704862_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000008091 64.0
TH2_k127_5715496_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 470.0
TH2_k127_5715496_1 Putative metal-binding motif - - - 0.00000000000000000004871 106.0
TH2_k127_572504_0 TIGRFAM conserved repeat domain - - - 0.00000000000000000000004176 116.0
TH2_k127_5735029_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.366e-218 688.0
TH2_k127_5735029_1 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000001654 156.0
TH2_k127_5735029_2 Dual-action HEIGH metallo-peptidase - - - 0.000000000000000000000000004896 123.0
TH2_k127_5735029_3 Peptidase, M23 family - - - 0.0000000002531 72.0
TH2_k127_5735435_0 AAA domain K01551 - 3.6.3.16 4.494e-240 759.0
TH2_k127_5735435_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 519.0
TH2_k127_5735435_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 491.0
TH2_k127_5735435_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000001914 173.0
TH2_k127_5738893_0 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 406.0
TH2_k127_5738893_1 beta-lactamase - - - 0.00000000000000149 89.0
TH2_k127_5760452_0 - - - - 0.00000000000000000000000000000002797 126.0
TH2_k127_5760452_1 - - - - 0.000000000000000000000001604 108.0
TH2_k127_5760452_2 Lipopolysaccharide kinase (Kdo/WaaP) family K08884 - 2.7.11.1 0.000000000000004872 85.0
TH2_k127_5760452_3 Protein of unknown function (DUF1573) - - - 0.0000000613 65.0
TH2_k127_5791765_0 ABC transporter permease K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000706 317.0
TH2_k127_5791765_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 318.0
TH2_k127_5791765_2 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000008856 207.0
TH2_k127_5791765_3 - - - - 0.000000000000000000000000000000000002507 144.0
TH2_k127_5791765_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000009033 137.0
TH2_k127_5795635_0 - - - - 0.00000000000000000000000000000000000000004316 169.0
TH2_k127_5795635_1 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000000000000000002057 149.0
TH2_k127_5795635_3 Forkhead associated domain - - - 0.0008483 42.0
TH2_k127_579583_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 1.559e-241 760.0
TH2_k127_579583_1 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 383.0
TH2_k127_579583_2 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009229 266.0
TH2_k127_5796050_0 PEGA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 432.0
TH2_k127_5796050_1 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 399.0
TH2_k127_5800308_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 523.0
TH2_k127_5801937_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000009347 202.0
TH2_k127_5807801_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 376.0
TH2_k127_5807801_1 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 352.0
TH2_k127_5807801_2 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001329 250.0
TH2_k127_5807801_3 trisaccharide binding K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001746 254.0
TH2_k127_5807801_4 - K15125 - - 0.00000000000000007727 90.0
TH2_k127_5807801_5 lytic transglycosylase activity K21471,K21472 - - 0.0000003857 61.0
TH2_k127_5808097_0 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004676 260.0
TH2_k127_5808097_1 COG3911 Predicted ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004111 249.0
TH2_k127_5808097_2 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000002722 252.0
TH2_k127_5808097_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000004789 121.0
TH2_k127_5808097_4 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000001993 90.0
TH2_k127_5810339_0 heat shock protein 70 K04043 - - 2.977e-242 762.0
TH2_k127_5810339_1 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000003445 204.0
TH2_k127_5810339_2 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000009378 161.0
TH2_k127_5810339_3 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.0000000000000000000000000000000008649 138.0
TH2_k127_5811627_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 3.771e-202 636.0
TH2_k127_5811627_1 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000001026 178.0
TH2_k127_5811627_2 photosystem II stabilization K00784,K02237 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.1.26.11 0.0000000000000000003864 102.0
TH2_k127_5817835_0 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000107 242.0
TH2_k127_5817835_1 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000274 225.0
TH2_k127_5817835_2 Belongs to the TPP enzyme family - - - 0.000000000000000000001054 99.0
TH2_k127_5818109_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 336.0
TH2_k127_5818109_1 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000002989 147.0
TH2_k127_583233_0 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000002155 223.0
TH2_k127_583233_1 S1 P1 Nuclease - - - 0.000000000000000003552 96.0
TH2_k127_5882043_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 613.0
TH2_k127_5882043_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 479.0
TH2_k127_5882043_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 359.0
TH2_k127_5882043_3 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003929 282.0
TH2_k127_5882043_4 Thioredoxin-like [2Fe-2S] ferredoxin - - - 0.0000000000000000000000000000003372 128.0
TH2_k127_5882043_5 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000008735 89.0
TH2_k127_58837_0 4'-phosphopantetheinyl transferase superfamily - - - 0.00000000000000000000000005883 116.0
TH2_k127_58837_1 FHA domain - - - 0.000000000004898 78.0
TH2_k127_5892347_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 463.0
TH2_k127_5892347_1 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000993 101.0
TH2_k127_5892347_2 GIY-YIG catalytic domain K07461 - - 0.000000000000000002765 99.0
TH2_k127_5892347_3 serine threonine protein kinase - - - 0.00007547 49.0
TH2_k127_590904_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 343.0
TH2_k127_590904_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002127 253.0
TH2_k127_590904_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001456 258.0
TH2_k127_590904_3 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000002955 226.0
TH2_k127_5937606_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 317.0
TH2_k127_5937606_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000008385 134.0
TH2_k127_593899_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 554.0
TH2_k127_593899_1 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 529.0
TH2_k127_593899_2 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000825 186.0
TH2_k127_5964327_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 610.0
TH2_k127_5964327_1 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 565.0
TH2_k127_5964327_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 306.0
TH2_k127_5964327_3 Serine aminopeptidase, S33 K07018 - - 0.0000000000000000000000000000000000000000000000000004946 190.0
TH2_k127_5977011_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 576.0
TH2_k127_5977011_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 402.0
TH2_k127_5977011_2 DNA-dependent DNA replication K02315,K04076 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 306.0
TH2_k127_5982382_0 Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 353.0
TH2_k127_5982382_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000003674 208.0
TH2_k127_5982382_2 Protein of unknown function (DUF2378) - - - 0.0000000000000000000004349 108.0
TH2_k127_5982382_3 ApaG domain K06195 - - 0.00000000000000000004053 89.0
TH2_k127_598879_0 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 557.0
TH2_k127_598879_1 ATPases associated with a variety of cellular activities K02049,K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002364 248.0
TH2_k127_598879_2 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000003092 245.0
TH2_k127_598879_3 Binding-protein-dependent transport system inner membrane component K15552 - - 0.00000000000000000000000000000000000000000000000000000000009513 213.0
TH2_k127_598879_4 - - - - 0.0000000000005736 82.0
TH2_k127_598879_5 Gaf domain K21009 - - 0.00000000002293 71.0
TH2_k127_5991058_0 Glycosyl transferases group 1 - - - 4.455e-205 654.0
TH2_k127_5991058_1 ABC-2 type transporter K09688,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000874 226.0
TH2_k127_5995076_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 340.0
TH2_k127_5995076_1 Putative metal-binding motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000002972 262.0
TH2_k127_599752_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 1.896e-210 659.0
TH2_k127_599752_1 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 362.0
TH2_k127_599752_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000002127 78.0
TH2_k127_6003476_0 Putative zinc-finger K03088 - - 0.0000000000000000000000000000000000000000000000000685 186.0
TH2_k127_6003476_1 Limonene-1,2-epoxide hydrolase catalytic domain - - - 0.00000000000000000000000000000000000000000000002202 175.0
TH2_k127_6003476_2 - - - - 0.0000000000000000000000000000000001564 142.0
TH2_k127_6009916_0 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 417.0
TH2_k127_6009916_1 Glycosyl hydrolases family 31 K01811,K15922 - 3.2.1.177,3.2.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 354.0
TH2_k127_6009916_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000008207 261.0
TH2_k127_6009916_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000008084 196.0
TH2_k127_6009916_4 histone H2A K63-linked ubiquitination - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000002126 104.0
TH2_k127_6016187_1 Uncharacterized protein conserved in bacteria (DUF2058) - - - 0.000000000000000000000000000000000001605 158.0
TH2_k127_6016187_2 Cold-shock protein K03704 - - 0.000000000000000000000000000000001716 132.0
TH2_k127_6042353_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 398.0
TH2_k127_6042353_1 - - - - 0.000000000000000000000000001949 129.0
TH2_k127_6042353_2 Glycosyl hydrolase-like 10 - - - 0.000000000000000001001 94.0
TH2_k127_6050983_0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005923 272.0
TH2_k127_6050983_1 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.00000000000000000000000000000002203 137.0
TH2_k127_6059706_0 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 554.0
TH2_k127_6059706_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 522.0
TH2_k127_6059706_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 398.0
TH2_k127_6059706_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 351.0
TH2_k127_6059706_4 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 313.0
TH2_k127_6071270_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 595.0
TH2_k127_6071270_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 254.0
TH2_k127_6071270_2 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000004171 205.0
TH2_k127_6071270_3 Memo-like protein K06990 - - 0.0000000000006743 69.0
TH2_k127_6078605_0 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 299.0
TH2_k127_6078605_1 protein, hemolysin III K11068 - - 0.000000000000000000000000000000000000000000000000000000003081 207.0
TH2_k127_6078605_2 metallopeptidase activity K01179,K07004,K12548 - 3.2.1.4 0.000000000000000000000000000002285 141.0
TH2_k127_6085560_0 Belongs to the thiolase family K00626 - 2.3.1.9 2.219e-213 667.0
TH2_k127_6085560_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 390.0
TH2_k127_6085560_2 Transcriptional regulator K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 329.0
TH2_k127_6085560_3 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001165 247.0
TH2_k127_6085560_4 diguanylate cyclase - - - 0.000000000000000000000000000001879 132.0
TH2_k127_6086675_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000003707 216.0
TH2_k127_6086675_1 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000002292 62.0
TH2_k127_6114226_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 514.0
TH2_k127_6114226_1 Site-specific recombinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 429.0
TH2_k127_6118533_0 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 463.0
TH2_k127_6118533_1 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000003753 216.0
TH2_k127_6155129_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 358.0
TH2_k127_6155129_1 transferase hexapeptide repeat containing protein K00966,K16881 - 2.7.7.13,5.4.2.8 0.00009331 53.0
TH2_k127_6171315_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 3.228e-287 892.0
TH2_k127_6171315_1 Ergosterol biosynthesis ERG4/ERG24 family K00213,K00223 - 1.3.1.21,1.3.1.71 1.761e-206 654.0
TH2_k127_6171315_2 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0000000006438 64.0
TH2_k127_6174979_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000001235 136.0
TH2_k127_6174979_1 PFAM CBS domain containing protein K04767 - - 0.00000000000005145 80.0
TH2_k127_6174979_2 hemerythrin HHE cation binding domain - - - 0.0001834 50.0
TH2_k127_6184950_0 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 576.0
TH2_k127_6184950_1 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 324.0
TH2_k127_619008_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 617.0
TH2_k127_619008_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 575.0
TH2_k127_619008_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000001015 199.0
TH2_k127_619008_3 penicillin-binding protein K03587 - 3.4.16.4 0.0000000000006623 70.0
TH2_k127_623257_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.444e-205 646.0
TH2_k127_623257_1 SMART helicase c2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 312.0
TH2_k127_623257_2 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 299.0
TH2_k127_623257_4 - - - - 0.0000000000000000000000000000000004259 149.0
TH2_k127_623257_5 - - - - 0.000000000000000000000000001431 129.0
TH2_k127_6232858_0 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 5.674e-235 738.0
TH2_k127_6232858_1 Specifically methylates the guanosine in position 1516 of 16S rRNA - - - 0.00000000000000000000000000000000000000000000000000001143 210.0
TH2_k127_6232858_2 phosphonate ABC transporter, periplasmic K02044 - - 0.00000000000000000000000000000000000000000006904 174.0
TH2_k127_6232858_3 Cache domain - - - 0.00000000007276 64.0
TH2_k127_6233361_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 9.762e-272 851.0
TH2_k127_6245734_0 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 305.0
TH2_k127_6245734_1 Transaldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008791 291.0
TH2_k127_6245734_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000001173 88.0
TH2_k127_6252134_0 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 387.0
TH2_k127_6252134_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 339.0
TH2_k127_6252134_2 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007769 271.0
TH2_k127_6252134_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000002553 192.0
TH2_k127_6270019_0 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000009326 243.0
TH2_k127_6270019_1 GMC oxidoreductase - - - 0.00000000000000000005697 91.0
TH2_k127_6270019_2 - - - - 0.0000000000000001547 89.0
TH2_k127_6271931_0 Efflux ABC transporter, permease ATP-binding protein K06147 - - 1.301e-233 736.0
TH2_k127_6273959_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005254 591.0
TH2_k127_6273959_1 Thioesterase-like superfamily K07107 - - 0.000000000000000001844 88.0
TH2_k127_6273959_2 - - - - 0.0008031 52.0
TH2_k127_6292187_0 DNA helicase K03656,K03657 - 3.6.4.12 2.817e-287 899.0
TH2_k127_6292187_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000008135 238.0
TH2_k127_6292187_2 D-aminopeptidase K16203 - - 0.00000000000000000008035 104.0
TH2_k127_6302084_0 Family membership K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 397.0
TH2_k127_630548_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 1.225e-232 728.0
TH2_k127_630548_1 Peptidase family M28 - - - 2.709e-217 687.0
TH2_k127_630548_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 324.0
TH2_k127_630548_3 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000004317 232.0
TH2_k127_630548_5 Acyl-transferase - - - 0.0000000000000000000000000000000000000000004272 168.0
TH2_k127_630548_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000486 88.0
TH2_k127_6329570_0 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 391.0
TH2_k127_6329570_2 Oxidoreductase NAD-binding domain - - - 0.000000000002581 72.0
TH2_k127_6329570_3 - - - - 0.00000000134 60.0
TH2_k127_6339338_0 Belongs to the RimK family K05844,K14940 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 6.3.2.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003834 276.0
TH2_k127_6339338_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000002412 276.0
TH2_k127_6339338_2 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003598 250.0
TH2_k127_6339338_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000001293 179.0
TH2_k127_6347375_0 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001948 264.0
TH2_k127_6347375_1 Polysulphide reductase K00185 - - 0.000000000000000000000000000000000000252 159.0
TH2_k127_6368462_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001648 289.0
TH2_k127_6368462_1 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000002897 195.0
TH2_k127_6368462_2 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000002859 66.0
TH2_k127_6368462_3 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00001552 57.0
TH2_k127_6396266_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001721 300.0
TH2_k127_6396266_1 UDP-glucoronosyl and UDP-glucosyl transferase K16444 - 2.4.1.310 0.00000000000000000000000000000000000000000000000000000000000000000000003244 261.0
TH2_k127_6396266_2 protein trimerization - - - 0.000000000000000179 90.0
TH2_k127_6396266_3 cellulose binding - - - 0.00000497 59.0
TH2_k127_644011_0 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 442.0
TH2_k127_644011_1 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000000000000000000000009488 217.0
TH2_k127_644011_2 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000001844 214.0
TH2_k127_644011_3 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000000000000113 193.0
TH2_k127_644011_4 - - - - 0.0000000000000000000000000000002002 135.0
TH2_k127_6442654_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 535.0
TH2_k127_6442654_1 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000003336 182.0
TH2_k127_6443274_0 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 2.282e-258 809.0
TH2_k127_6443274_1 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 366.0
TH2_k127_6443274_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 323.0
TH2_k127_6443274_3 Bacterial protein of unknown function (YtfJ_HI0045) K07109 - - 0.0000000000000000000000000000617 126.0
TH2_k127_6468046_0 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 344.0
TH2_k127_6470308_0 Pyruvate flavodoxin ferredoxin K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 407.0
TH2_k127_6470308_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 418.0
TH2_k127_6470308_2 PilZ domain - - - 0.00004235 54.0
TH2_k127_6477503_0 FAD dependent oxidoreductase K07137 - - 2.75e-259 806.0
TH2_k127_6477503_1 Nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000003779 141.0
TH2_k127_6477503_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000008797 117.0
TH2_k127_6477503_3 - - - - 0.000000000001189 70.0
TH2_k127_6479605_0 - - - - 0.000000000000000000000000000000001889 147.0
TH2_k127_6482873_0 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 405.0
TH2_k127_6482873_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003155 273.0
TH2_k127_6488932_0 Type IV pilus assembly protein PilM; K02461 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 571.0
TH2_k127_6488932_1 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 405.0
TH2_k127_6488932_3 Type II secretion system (T2SS), protein M K02462 - - 0.00000000000000000000000000000000000000000000000000005447 195.0
TH2_k127_6488932_4 - - - - 0.00000000000000000000000000001148 134.0
TH2_k127_6488932_5 - - - - 0.0000001203 61.0
TH2_k127_6493900_0 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003153 293.0
TH2_k127_6493900_1 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000001359 186.0
TH2_k127_6499279_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 458.0
TH2_k127_6499279_1 - - - - 0.00000001338 64.0
TH2_k127_6501993_0 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007288 284.0
TH2_k127_6501993_1 - - - - 0.0000000000000000000000001965 119.0
TH2_k127_6501993_2 ABC transporter K15738 - - 0.0000000000000002777 80.0
TH2_k127_6503505_0 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 363.0
TH2_k127_6503505_1 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 324.0
TH2_k127_6503505_2 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 331.0
TH2_k127_6503505_3 SMART Rhodanese domain protein - - - 0.00000002735 61.0
TH2_k127_6503505_4 PFAM Metallophosphoesterase K07098 - - 0.0006651 43.0
TH2_k127_6510052_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1028.0
TH2_k127_6510052_1 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005405 262.0
TH2_k127_6510052_2 glycerophosphoryl diester phosphodiesterase - - - 0.000000000000000000000000000000000000000004015 167.0
TH2_k127_6513770_0 Cytochrome c-type biogenesis protein K02198 - - 2.11e-279 873.0
TH2_k127_6513770_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 315.0
TH2_k127_6513770_2 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 296.0
TH2_k127_6513770_3 ATPase activity K01990,K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000001544 256.0
TH2_k127_6513770_4 CcmE K02197 - - 0.000000000000000000000000000000000000000000000000000000000000000008022 228.0
TH2_k127_6513770_5 Domain of unknown function (DUF4350) - - - 0.00000000000000000000000000000000000000000000000000000000000000502 233.0
TH2_k127_6513770_6 Redoxin K02199 - - 0.000000000000000000000000000000000000000000002493 188.0
TH2_k127_6513770_7 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.000000000001521 71.0
TH2_k127_6513770_8 - - - - 0.000007176 55.0
TH2_k127_6523559_0 B3/4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004337 224.0
TH2_k127_6525665_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 607.0
TH2_k127_6525665_1 fumarate reductase) cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000009678 153.0
TH2_k127_6548350_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 526.0
TH2_k127_6548350_1 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA K06169 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005083 253.0
TH2_k127_6548350_2 Protein kinase domain - - - 0.0000000000004774 78.0
TH2_k127_6569684_0 von Willebrand factor type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 360.0
TH2_k127_6569684_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001854 276.0
TH2_k127_6570595_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 552.0
TH2_k127_6570595_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000001623 139.0
TH2_k127_6578583_0 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 350.0
TH2_k127_6578583_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001035 239.0
TH2_k127_6596997_0 SPFH domain / Band 7 family - - - 1.417e-221 704.0
TH2_k127_6596997_1 PhoD-like phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007043 292.0
TH2_k127_6596997_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005904 256.0
TH2_k127_6596997_3 Forkhead associated domain - - - 0.000000000000008502 85.0
TH2_k127_6599444_1 integral membrane protein - - - 0.00002967 53.0
TH2_k127_6605101_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 545.0
TH2_k127_6605101_1 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 362.0
TH2_k127_6615136_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 2.608e-265 826.0
TH2_k127_6615136_1 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 352.0
TH2_k127_6615136_2 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 323.0
TH2_k127_6615136_3 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000007315 225.0
TH2_k127_6615136_4 nucleic acid-binding protein contains PIN domain K18828 - - 0.000000000000000000000000000000000000001308 155.0
TH2_k127_6615136_5 PFAM FIST C domain - - - 0.000000000000000000000000006702 126.0
TH2_k127_6615136_6 serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000000000000000000000009793 112.0
TH2_k127_6615136_7 Protein of unknown function (DUF559) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000004384 107.0
TH2_k127_6615136_9 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000001 67.0
TH2_k127_6621436_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 1.177e-310 1013.0
TH2_k127_6621436_1 Type IV Pilus-assembly protein W K02672 - - 0.00000000000000000000000000000000000000000000004635 183.0
TH2_k127_6643134_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 565.0
TH2_k127_6643134_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 528.0
TH2_k127_6643134_2 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 439.0
TH2_k127_6643134_3 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 284.0
TH2_k127_6643134_4 Chitinase class I K03791 - - 0.00000000000000000000000000000000000000000000000000000000000000000003067 246.0
TH2_k127_6643134_5 Beta-propeller repeat - - - 0.0000000000000000000000000000001034 143.0
TH2_k127_6643134_6 beta-fructofuranosidase activity - - - 0.000000000000000000000000000002396 138.0
TH2_k127_6703974_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000001173 158.0
TH2_k127_6703974_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000002188 136.0
TH2_k127_6703974_2 Molybdopterin oxidoreductase K00123 - 1.17.1.9 0.00000000000000000000000000001092 120.0
TH2_k127_6703974_3 GntR family - - - 0.000001515 57.0
TH2_k127_6707352_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 360.0
TH2_k127_6707352_1 Thioredoxin K03671 - - 0.0000000000000000000000000000000000008951 146.0
TH2_k127_6707352_2 MORN repeat variant - - - 0.0000000000000006516 93.0
TH2_k127_6707352_4 Thioredoxin domain-containing protein K05838 - - 0.0000000005304 61.0
TH2_k127_6708600_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000111 172.0
TH2_k127_6708600_2 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000737 74.0
TH2_k127_6711498_0 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004918 269.0
TH2_k127_6711498_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000008992 76.0
TH2_k127_6711498_2 von Willebrand factor type A domain - - - 0.000001217 61.0
TH2_k127_6727482_0 Cytochrome C and Quinol oxidase polypeptide I - - - 3.72e-239 746.0
TH2_k127_6727482_1 4Fe-4S dicluster domain K00184 - - 3.593e-232 766.0
TH2_k127_6727482_2 Polysulphide reductase, NrfD K00185 - - 7.51e-204 642.0
TH2_k127_6727482_3 Cytochrome c oxidase subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006606 247.0
TH2_k127_6727482_4 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001251 246.0
TH2_k127_6727482_5 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000001672 167.0
TH2_k127_6727482_6 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000002079 151.0
TH2_k127_6727482_8 protein SCO1 SenC K07152 - - 0.000000001198 70.0
TH2_k127_6736442_0 FCD K05799 - - 0.00000000000000000000000001553 118.0
TH2_k127_6736442_1 - - - - 0.000000000000001592 90.0
TH2_k127_6736442_2 belongs to the aldehyde dehydrogenase family K00154,K22445 - 1.2.1.68,1.2.99.10 0.00005725 48.0
TH2_k127_6740260_0 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 549.0
TH2_k127_6740260_1 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001922 252.0
TH2_k127_6740260_2 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000001566 104.0
TH2_k127_6740260_3 - - - - 0.0000000000000002954 91.0
TH2_k127_6740260_4 CAAX protease self-immunity - - - 0.0000000000000006705 88.0
TH2_k127_6747663_0 Amidohydrolase family - - - 0.00000000000000000000000000002257 122.0
TH2_k127_6747663_1 serine-type endopeptidase activity - - - 0.000000000000000000000000004773 127.0
TH2_k127_6747663_2 serine-type endopeptidase activity - - - 0.0000000000000000000003452 111.0
TH2_k127_6747663_3 GGDEF domain - - - 0.00005834 50.0
TH2_k127_6781134_0 Choline/ethanolamine kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 513.0
TH2_k127_6781134_1 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 420.0
TH2_k127_6781134_2 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 387.0
TH2_k127_6781134_3 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000311 234.0
TH2_k127_6781134_4 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000006704 151.0
TH2_k127_6783043_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 451.0
TH2_k127_6783043_1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 321.0
TH2_k127_678344_0 Chitinase class I K03791 - - 0.00000000000000000000000000000981 129.0
TH2_k127_678344_1 peptidase K01392 - 3.4.24.15 0.00000000000000003079 97.0
TH2_k127_678344_2 Leucine rich repeats (6 copies) - - - 0.000000000000001969 86.0
TH2_k127_678344_3 Tetratricopeptide repeat - - - 0.0001924 54.0
TH2_k127_6797153_0 pilus organization - - - 0.0000000000000000000000000000000000000000000000000000002206 208.0
TH2_k127_6797153_2 - - - - 0.000000000000000000003776 101.0
TH2_k127_6800850_0 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001499 280.0
TH2_k127_6800850_1 - - - - 0.0000000000000000000000000000000000000000000000000000006294 205.0
TH2_k127_6800850_3 PTS system K02795 - - 0.0000001623 53.0
TH2_k127_680878_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1069.0
TH2_k127_680878_1 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000002101 228.0
TH2_k127_6810429_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 547.0
TH2_k127_6810429_1 glutamate--cysteine ligase K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 441.0
TH2_k127_6810429_2 high-affinity sulfate:proton symporter activity K06203 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600 - 0.00000000000000000000000000000000000000000000001593 184.0
TH2_k127_683213_0 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 556.0
TH2_k127_683213_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000005134 257.0
TH2_k127_683213_2 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000004365 189.0
TH2_k127_683213_3 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000192 206.0
TH2_k127_6834393_0 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 471.0
TH2_k127_6834393_1 - - - - 0.00000000005706 64.0
TH2_k127_6844622_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 515.0
TH2_k127_6844622_1 domain, Protein K01212,K12287,K20276 - 3.2.1.65 0.00000000000000000000000000000000000000000000000000000000006227 226.0
TH2_k127_6844622_2 Homologues of snake disintegrins - - - 0.0000000000000000000000000000000005036 150.0
TH2_k127_6844622_3 -acetyltransferase - - - 0.00001966 52.0
TH2_k127_6853013_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 337.0
TH2_k127_6853013_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001129 256.0
TH2_k127_6853013_2 Abhydrolase domain containing 18 - - - 0.000945 43.0
TH2_k127_6862847_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.619e-265 825.0
TH2_k127_6866175_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 593.0
TH2_k127_6866175_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000029 205.0
TH2_k127_6866175_2 Signal transduction histidine kinase, nitrogen specific - - - 0.00000000000000000000000000000000000000000006154 178.0
TH2_k127_6866542_0 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 290.0
TH2_k127_6866542_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000001023 261.0
TH2_k127_6866542_2 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001641 247.0
TH2_k127_6866542_3 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004653 252.0
TH2_k127_6866542_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002266 240.0
TH2_k127_6866542_5 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000001605 130.0
TH2_k127_6866542_6 Peptidase family M50 K11749 - - 0.000000000000000000002065 94.0
TH2_k127_6866542_8 - - - - 0.00000000002573 77.0
TH2_k127_6875825_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 375.0
TH2_k127_6875825_1 PFAM MCP methyltransferase, CheR-type K00575,K13486 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 316.0
TH2_k127_6875825_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000006684 196.0
TH2_k127_6875825_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000001036 184.0
TH2_k127_6875825_4 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000004055 171.0
TH2_k127_6875825_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000001263 153.0
TH2_k127_6875825_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000001533 86.0
TH2_k127_6876905_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 3.924e-223 702.0
TH2_k127_6876905_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 532.0
TH2_k127_6876905_10 - - - - 0.00007549 48.0
TH2_k127_6876905_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 318.0
TH2_k127_6876905_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 280.0
TH2_k127_6876905_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000008571 262.0
TH2_k127_6876905_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000149 184.0
TH2_k127_6876905_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000376 172.0
TH2_k127_6876905_7 Could be involved in septation K06412 - - 0.000000000000000000000000000000000001733 143.0
TH2_k127_6876905_8 Ribosomal protein L35 K02916 - - 0.0000000000000000000000000003517 123.0
TH2_k127_6876905_9 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.0000000000000000000003217 107.0
TH2_k127_6883451_0 PFAM NnrS family protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 461.0
TH2_k127_6883451_1 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 414.0
TH2_k127_6883451_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000003653 207.0
TH2_k127_6886435_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 406.0
TH2_k127_6886435_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004895 281.0
TH2_k127_6886435_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000009842 228.0
TH2_k127_6886435_3 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000005252 172.0
TH2_k127_6886435_4 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.00008109 53.0
TH2_k127_6898429_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006461 272.0
TH2_k127_6898429_1 TonB dependent receptor - - - 0.0000000000000000000000000005115 122.0
TH2_k127_6910063_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 322.0
TH2_k127_6916719_0 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003367 270.0
TH2_k127_6916719_1 - - - - 0.000008879 57.0
TH2_k127_6924276_0 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000001167 207.0
TH2_k127_6924276_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000002159 207.0
TH2_k127_6925388_0 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 506.0
TH2_k127_6925388_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000002569 69.0
TH2_k127_6925637_0 cell adhesion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 533.0
TH2_k127_6928975_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 626.0
TH2_k127_6941427_0 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 1.169e-204 649.0
TH2_k127_6941427_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000005583 119.0
TH2_k127_6947710_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 335.0
TH2_k127_6947710_1 - - - - 0.0000000000000000000000000000000000000000000000000000000002561 227.0
TH2_k127_6947710_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000001021 154.0
TH2_k127_6956738_0 Type III secretion protein K03230 - - 2.578e-216 699.0
TH2_k127_6956738_1 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003954 270.0
TH2_k127_6956738_2 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401,K03229 - - 0.0000000000000000000000000000000000000000000000000004132 189.0
TH2_k127_6956738_3 regulation of translation K05788 - - 0.000000000000000000000000000000000000000000000004271 179.0
TH2_k127_6960671_0 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases - - - 0.000002734 60.0
TH2_k127_6960671_1 Carotenoid biosynthesis protein K22502 - 5.5.1.19 0.000003131 58.0
TH2_k127_6960721_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 422.0
TH2_k127_6960721_1 DAHP synthetase I family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 411.0
TH2_k127_6960721_2 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000363 75.0
TH2_k127_6963120_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 440.0
TH2_k127_6963120_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000002574 149.0
TH2_k127_6963120_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000006015 86.0
TH2_k127_6973110_0 PFAM extracellular solute-binding protein family 1 K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 416.0
TH2_k127_6973110_1 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.0000000000000000000000000000000000000000101 158.0
TH2_k127_6973110_2 O-methyltransferase - - - 0.00000000000000000000000004284 117.0
TH2_k127_6973110_3 Carotenoid biosynthesis protein - - - 0.0002991 53.0
TH2_k127_6974774_0 Short chain fatty acid transporter K02106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 610.0
TH2_k127_6974774_1 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 329.0
TH2_k127_6974774_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K13509 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000484 196.0
TH2_k127_6974774_3 - - - - 0.0000000000000000000000000000000003206 141.0
TH2_k127_6974774_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000007538 78.0
TH2_k127_6981774_0 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 517.0
TH2_k127_6981774_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000002307 152.0
TH2_k127_6981774_2 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000007614 131.0
TH2_k127_6981774_3 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000003996 103.0
TH2_k127_6981774_4 CBS domain - - - 0.0000000000000000001145 96.0
TH2_k127_6983279_1 - - - - 0.00000000000001953 73.0
TH2_k127_6989001_0 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 403.0
TH2_k127_6989001_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 318.0
TH2_k127_6989001_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000002168 156.0
TH2_k127_6991985_0 IMP dehydrogenase GMP reductase K00088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.1.1.205 5.319e-201 636.0
TH2_k127_6991985_1 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 489.0
TH2_k127_6991985_2 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000004651 229.0
TH2_k127_6991985_3 COG COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000005597 142.0
TH2_k127_6991985_4 YjbR - - - 0.00000000000000000000000000007381 120.0
TH2_k127_6991985_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000003263 119.0
TH2_k127_6991985_6 calcium ion binding - - - 0.0000000000000000004869 96.0
TH2_k127_7003967_0 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 494.0
TH2_k127_70163_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1083.0
TH2_k127_70163_1 4Fe-4S dicluster domain K00371,K17051 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 499.0
TH2_k127_70163_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000002334 190.0
TH2_k127_70163_3 chaperone-mediated protein complex assembly - - - 0.00000000000000000000000000000000001536 153.0
TH2_k127_70163_4 Cytochrome c K07243 - - 0.0000000000000000003518 93.0
TH2_k127_70163_5 component of anaerobic - - - 0.0000000000000008514 91.0
TH2_k127_7041693_0 cell adhesion involved in biofilm formation - - - 0.000000000004497 78.0
TH2_k127_7041693_1 Galactose oxidase, central domain - - - 0.000000007012 69.0
TH2_k127_7058950_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 458.0
TH2_k127_7058950_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000003962 183.0
TH2_k127_7058950_2 PFAM Dienelactone hydrolase - - - 0.00000000000001021 76.0
TH2_k127_7072032_0 belongs to the thioredoxin family K03671,K05838 - - 0.00000000000000000000000000000002388 136.0
TH2_k127_7073673_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 544.0
TH2_k127_7073673_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 425.0
TH2_k127_7073673_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001643 278.0
TH2_k127_7074024_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 317.0
TH2_k127_7074024_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000009013 114.0
TH2_k127_7074024_2 HD domain - - - 0.0000000000000000005428 99.0
TH2_k127_7074024_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000002251 59.0
TH2_k127_7081957_0 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 433.0
TH2_k127_7081957_1 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 303.0
TH2_k127_7081957_2 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000006805 253.0
TH2_k127_7090701_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 471.0
TH2_k127_7090701_1 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000000000000000000000000000000000003766 170.0
TH2_k127_7090701_2 Bacterial Ig-like domain - - - 0.000000005571 67.0
TH2_k127_7090701_3 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000001899 57.0
TH2_k127_7092238_0 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 400.0
TH2_k127_7092238_1 - - - - 0.0000000000000000000000000000000000000000000000000000000004454 230.0
TH2_k127_711119_1 FHA domain K01768 - 4.6.1.1 0.0003399 54.0
TH2_k127_711291_0 Beta-Casp domain K07576 - - 2.555e-216 700.0
TH2_k127_711291_1 Alg9-like mannosyltransferase family K05286 - - 0.0000000000000000000000001909 114.0
TH2_k127_7122006_0 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 336.0
TH2_k127_7122006_2 PQQ enzyme repeat - - - 0.00000000000000000000000000000003019 146.0
TH2_k127_7122006_3 4Fe-4S binding domain - - - 0.00000000000000007147 93.0
TH2_k127_7132854_0 7TM receptor with intracellular HD hydrolase K07037 - - 1.736e-299 939.0
TH2_k127_7132854_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 332.0
TH2_k127_7132854_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 312.0
TH2_k127_7132854_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000007833 152.0
TH2_k127_7132854_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000001933 79.0
TH2_k127_7132854_5 - - - - 0.0001298 49.0
TH2_k127_7133366_0 Beta-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 297.0
TH2_k127_7136534_0 radical SAM domain protein K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 609.0
TH2_k127_7136534_1 cysteine-type peptidase activity - - - 0.0000000000000000000000002665 123.0
TH2_k127_7137412_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 518.0
TH2_k127_7137412_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000007897 129.0
TH2_k127_7139163_0 COG0524 Sugar kinases, ribokinase family K00892 - 2.7.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 613.0
TH2_k127_7139163_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 552.0
TH2_k127_7139163_2 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 520.0
TH2_k127_7139163_3 transferase activity, transferring glycosyl groups K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000004295 233.0
TH2_k127_7139163_4 Belongs to the DsbB family K03611 - - 0.000000000005566 67.0
TH2_k127_7141577_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 586.0
TH2_k127_7141577_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 546.0
TH2_k127_7141577_2 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 409.0
TH2_k127_7141577_3 TonB family K03646,K03832 - - 0.000000000000000000000000000000000000000000000000000006733 196.0
TH2_k127_7150817_0 Forkhead associated domain - - - 4.273e-207 657.0
TH2_k127_7150817_1 TadE-like protein - - - 0.000000000000000000000000000000000000000000000000000000000001221 238.0
TH2_k127_7150817_2 PFAM TadE family protein - - - 0.00000000000000000000003827 115.0
TH2_k127_7150817_3 Sigma-70, region 4 K03088 - - 0.00000000000000000000008456 101.0
TH2_k127_7154178_0 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 456.0
TH2_k127_7154178_1 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 329.0
TH2_k127_7154178_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000001148 61.0
TH2_k127_7159517_0 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000004823 187.0
TH2_k127_7159517_1 Belongs to the ompA family K03640 - - 0.000000000000000000000005854 107.0
TH2_k127_7159517_2 MacB-like periplasmic core domain - - - 0.000000000003888 78.0
TH2_k127_7161100_0 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 384.0
TH2_k127_7161100_1 Lipopolysaccharide-assembly - - - 0.000000000000000004606 86.0
TH2_k127_7161100_2 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000003459 85.0
TH2_k127_7161100_3 Tetratricopeptide repeat - - - 0.0000000004591 67.0
TH2_k127_7161100_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0002788 53.0
TH2_k127_7172214_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 309.0
TH2_k127_7172214_1 START domain - - - 0.000000000000000000000000000000000000000000000001418 183.0
TH2_k127_7172214_2 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.00000000002967 66.0
TH2_k127_7183388_0 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000002533 222.0
TH2_k127_7183388_1 propanoyl-CoA C-acyltransferase activity K08764 GO:0000038,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008150,GO:0008152,GO:0008306,GO:0008355,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009791,GO:0009987,GO:0010033,GO:0010817,GO:0010883,GO:0010888,GO:0016137,GO:0016138,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019236,GO:0019637,GO:0019693,GO:0019748,GO:0019752,GO:0022611,GO:0032101,GO:0032501,GO:0032502,GO:0032787,GO:0032879,GO:0033814,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0040008,GO:0040012,GO:0040024,GO:0042048,GO:0042221,GO:0042445,GO:0042446,GO:0042579,GO:0042810,GO:0042811,GO:0043053,GO:0043054,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0048580,GO:0048582,GO:0048583,GO:0048638,GO:0048639,GO:0048856,GO:0050789,GO:0050793,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0055086,GO:0055115,GO:0061062,GO:0061063,GO:0065007,GO:0065008,GO:0071704,GO:0071981,GO:0072521,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901576,GO:1901657,GO:1901659,GO:1904069,GO:1904070,GO:1905952,GO:1905953,GO:2000026 2.3.1.176 0.0000003397 57.0
TH2_k127_7187856_0 - K15125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 580.0
TH2_k127_7192493_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 455.0
TH2_k127_7192493_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000036 110.0
TH2_k127_7194245_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 1.863e-200 638.0
TH2_k127_7194245_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 413.0
TH2_k127_7194245_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 291.0
TH2_k127_7200474_0 SMART Elongator protein 3 MiaB NifB K06935,K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000008787 215.0
TH2_k127_7200474_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K11206,K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000001646 203.0
TH2_k127_7200474_2 signal-transduction protein containing cAMP-binding and CBS domains K00031,K02342,K07182,K14446 - 1.1.1.42,1.3.1.85,2.7.7.7 0.00000000000000000000005771 108.0
TH2_k127_7200474_3 Bacterial membrane protein YfhO - - - 0.0000001315 56.0
TH2_k127_7208557_0 thiolester hydrolase activity - - - 0.000000000000000008559 99.0
TH2_k127_7208557_1 Type II/IV secretion system protein K02454 - - 0.000000000001112 78.0
TH2_k127_7225177_0 PHP domain protein - - - 0.0000000000000000000000000000000000000003517 169.0
TH2_k127_7225177_1 NHL repeat - - - 0.0000000000000000000000000000000000001252 152.0
TH2_k127_7236004_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 8.88e-217 685.0
TH2_k127_7236004_1 - - - - 0.00000000000000000000001347 104.0
TH2_k127_7236004_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000005999 83.0
TH2_k127_7253052_0 Phosphofructokinase K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 548.0
TH2_k127_7253052_1 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000001014 181.0
TH2_k127_7253052_2 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000000000000000000006226 168.0
TH2_k127_7253052_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000001411 68.0
TH2_k127_7254117_0 twitching motility protein K02669 - - 3.804e-209 653.0
TH2_k127_7254117_1 Type II secretion system (T2SS), protein F K02653 - - 4.386e-195 616.0
TH2_k127_7254117_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 597.0
TH2_k127_7254117_3 PAS domain K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000001336 220.0
TH2_k127_725898_0 Transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 371.0
TH2_k127_725898_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 368.0
TH2_k127_7274660_0 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 2.08e-205 648.0
TH2_k127_7274660_1 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 490.0
TH2_k127_7274660_2 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 482.0
TH2_k127_7274660_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 423.0
TH2_k127_7274660_4 Protein of unknown function (DUF819) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 352.0
TH2_k127_7274660_5 cellulose binding - - - 0.000000000000000000000000005703 127.0
TH2_k127_7275827_0 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000000002973 163.0
TH2_k127_7275827_1 - - - - 0.0000413 53.0
TH2_k127_728553_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.387e-196 622.0
TH2_k127_728553_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 337.0
TH2_k127_728553_2 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000004377 181.0
TH2_k127_728553_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000001889 144.0
TH2_k127_728553_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000007674 53.0
TH2_k127_72896_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.126e-206 651.0
TH2_k127_72896_1 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 483.0
TH2_k127_72896_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000001096 192.0
TH2_k127_72896_3 Alg9-like mannosyltransferase family K05286 - - 0.0000000000000000000000000000000009238 135.0
TH2_k127_72896_5 Recombinase zinc beta ribbon domain K06400 - - 0.000001576 51.0
TH2_k127_7333970_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 599.0
TH2_k127_7333970_1 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 417.0
TH2_k127_7333970_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 310.0
TH2_k127_7333970_3 translation initiation factor activity K08884,K12132 - 2.7.11.1 0.0000000000000000001673 88.0
TH2_k127_7336050_0 Xanthine and CO dehydrogenases maturation factor XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 328.0
TH2_k127_7336050_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006431 240.0
TH2_k127_7336050_2 MOSC domain - - - 0.0000000000000000000000000000000000000000000000001451 199.0
TH2_k127_7336050_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000412 166.0
TH2_k127_7336050_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000001552 156.0
TH2_k127_7336050_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000007273 59.0
TH2_k127_7348810_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.561e-251 788.0
TH2_k127_7348810_1 Pyroglutamyl-peptidase I (PGP) K01304 - 3.4.19.3 0.0001266 54.0
TH2_k127_7351351_0 Selenocysteine-specific translation elongation factor K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 386.0
TH2_k127_7351351_1 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000000000000001872 220.0
TH2_k127_7393070_0 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004958 273.0
TH2_k127_7393070_1 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000002887 236.0
TH2_k127_7393070_2 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000005001 124.0
TH2_k127_7407832_1 protein kinase activity - - - 0.000000006512 61.0
TH2_k127_7415240_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000002014 130.0
TH2_k127_7415240_1 extracellular matrix structural constituent - - - 0.00002031 55.0
TH2_k127_7417413_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 456.0
TH2_k127_7417413_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000224 227.0
TH2_k127_743329_0 hydrogenase expression formation protein HypE K04655 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0018193,GO:0018198,GO:0018249,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046892,GO:0051604,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 376.0
TH2_k127_743329_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 313.0
TH2_k127_743329_2 Uroporphyrinogen decarboxylase activity. It is involved in the biological process described with porphyrin-containing compound biosynthetic process K01599 GO:0001889,GO:0003674,GO:0003824,GO:0004853,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009636,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010039,GO:0010243,GO:0014070,GO:0014075,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0031974,GO:0031981,GO:0032355,GO:0032501,GO:0032502,GO:0033013,GO:0033014,GO:0033993,GO:0034641,GO:0042168,GO:0042221,GO:0042440,GO:0042493,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045471,GO:0046148,GO:0046483,GO:0046502,GO:0046677,GO:0046685,GO:0046689,GO:0046872,GO:0046914,GO:0048513,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0051186,GO:0051188,GO:0051597,GO:0051716,GO:0060992,GO:0061008,GO:0070013,GO:0070887,GO:0071243,GO:0071704,GO:0097305,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901698,GO:1901700 4.1.1.37 0.00000000000000000000002872 102.0
TH2_k127_7434224_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 9.746e-205 646.0
TH2_k127_7434224_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 336.0
TH2_k127_7434224_2 zinc ion binding K06204 - - 0.00000000000000000000000000000000000007046 149.0
TH2_k127_7440853_0 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000001555 202.0
TH2_k127_7440853_1 B12 binding domain - - - 0.00000000000000001475 84.0
TH2_k127_7461882_0 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000001592 204.0
TH2_k127_7461882_1 OmpA family K03286 - - 0.00000000000000000000000000000000000000000000000000000217 208.0
TH2_k127_7461882_2 PilZ domain - - - 0.0000001562 57.0
TH2_k127_7461882_3 YdjC-like protein K03478 - 3.5.1.105 0.0002839 44.0
TH2_k127_746372_0 TIGRFAM glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 5.067e-231 731.0
TH2_k127_746372_1 - - - - 0.0000000000000000000000000000000000000000000000000000005515 200.0
TH2_k127_746372_2 enzyme binding K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.00000000000000005009 87.0
TH2_k127_7489498_0 Bacterial capsule synthesis protein PGA_cap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 440.0
TH2_k127_7489498_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000005766 148.0
TH2_k127_7489498_2 DNA ligase - - - 0.000000000001583 77.0
TH2_k127_7489721_0 Belongs to the peptidase M48B family - - - 0.000000000000000000000000000001339 130.0
TH2_k127_7489721_1 Predicted membrane protein (DUF2177) - - - 0.00000000000000000001857 95.0
TH2_k127_7489721_2 TIGRFAM Addiction module toxin, RelE StbE K19092 - - 0.0000000000000000001512 95.0
TH2_k127_7489721_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000001591 68.0
TH2_k127_7493116_0 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001774 249.0
TH2_k127_7493116_2 Tetratricopeptide repeat - - - 0.000000005215 66.0
TH2_k127_7502371_0 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 273.0
TH2_k127_7502371_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004836 249.0
TH2_k127_7502371_2 serine threonine protein kinase K08282,K08884,K11916,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001085 223.0
TH2_k127_7512933_0 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 422.0
TH2_k127_7512933_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 361.0
TH2_k127_7539357_0 SNF2 family N-terminal domain - - - 1.246e-280 886.0
TH2_k127_7539357_1 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.0000000000000000007201 91.0
TH2_k127_7574640_0 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 512.0
TH2_k127_7574640_1 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 435.0
TH2_k127_7574640_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000001264 222.0
TH2_k127_7574640_3 - - - - 0.000000000000000000000000000000003338 133.0
TH2_k127_7574640_4 Spherulation-specific family 4 - - - 0.00003771 48.0
TH2_k127_7584570_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 327.0
TH2_k127_7584570_1 Lamin Tail Domain K07004 - - 0.0000000000000000000000000000004808 132.0
TH2_k127_7584570_2 amine dehydrogenase activity - - - 0.0000003661 61.0
TH2_k127_7586254_0 Glycosyl transferase family 21 - - - 2.52e-251 784.0
TH2_k127_7586254_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 591.0
TH2_k127_7586254_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 434.0
TH2_k127_7586254_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003842 285.0
TH2_k127_7586254_4 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002321 250.0
TH2_k127_7586254_5 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000003006 244.0
TH2_k127_7586254_6 PFAM type II and III secretion system protein K02280 - - 0.00000005057 63.0
TH2_k127_7619735_0 Dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 520.0
TH2_k127_7619735_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 377.0
TH2_k127_7619735_2 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001116 261.0
TH2_k127_7619735_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000001628 139.0
TH2_k127_7619735_4 Protein of unknown function (DUF2892) - - - 0.0000000000000000001182 91.0
TH2_k127_7619735_5 Belongs to the peptidase S8 family K01342,K14645 - 3.4.21.62 0.000002335 61.0
TH2_k127_7619735_6 HAMP domain - - - 0.0003543 52.0
TH2_k127_7620071_0 Amidohydrolase family K05603 - 3.5.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 473.0
TH2_k127_7620071_1 - - - - 0.0000000001389 73.0
TH2_k127_7623871_0 ATPase with chaperone activity - - - 6.537e-211 679.0
TH2_k127_7623871_1 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000459 198.0
TH2_k127_7624223_0 2,4-dienoyl-coA reductase K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 529.0
TH2_k127_7624223_1 cellulose binding - - - 0.00000000000000000001118 107.0
TH2_k127_7645574_0 LppC putative lipoprotein K07121 - - 5.031e-249 788.0
TH2_k127_7645574_1 anaphase-promoting complex binding K20332 - - 0.0000000000000000000000000000179 134.0
TH2_k127_7677978_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 387.0
TH2_k127_7725602_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 348.0
TH2_k127_7725602_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000003479 222.0
TH2_k127_7725602_2 Ig-like domain from next to BRCA1 gene - - - 0.00000000000006272 85.0
TH2_k127_7736219_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 468.0
TH2_k127_7736219_1 AIG2-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008207 261.0
TH2_k127_7736219_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000005622 147.0
TH2_k127_7751473_0 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 317.0
TH2_k127_7751473_1 Pfam Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 307.0
TH2_k127_7751473_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005827 278.0
TH2_k127_7751473_3 - - - - 0.00000000000000000000000000000000000000000000000000000001936 216.0
TH2_k127_7751473_4 Late embryogenesis abundant protein - - - 0.00000000000000000000000000000000000000000000000000008931 196.0
TH2_k127_7751473_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000003831 161.0
TH2_k127_7756712_0 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 546.0
TH2_k127_7756712_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 495.0
TH2_k127_7756712_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000002103 210.0
TH2_k127_7756712_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000132 112.0
TH2_k127_7782583_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001434 284.0
TH2_k127_7782583_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000006614 238.0
TH2_k127_7782583_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000002175 101.0
TH2_k127_7782583_3 domain, Protein - - - 0.0000000000002668 83.0
TH2_k127_7789978_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 446.0
TH2_k127_7789978_1 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.0000002888 64.0
TH2_k127_7789978_2 NAD-dependent epimerase dehydratase K07071 - - 0.00001072 49.0
TH2_k127_7805774_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000001934 258.0
TH2_k127_7805774_1 - - - - 0.000000000006491 78.0
TH2_k127_7805774_2 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000004769 67.0
TH2_k127_7814069_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 374.0
TH2_k127_7814069_1 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 310.0
TH2_k127_7818276_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 4.695e-273 859.0
TH2_k127_7818276_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 2.612e-241 759.0
TH2_k127_7818276_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 5.504e-224 707.0
TH2_k127_7818276_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 9.853e-207 663.0
TH2_k127_7818276_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 306.0
TH2_k127_7818276_5 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000007344 174.0
TH2_k127_7818276_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000001197 145.0
TH2_k127_7818276_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000001346 148.0
TH2_k127_7818276_8 Protein kinase domain - - - 0.0000000000000000000000000000009434 123.0
TH2_k127_7827007_0 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 334.0
TH2_k127_7827007_1 Acyl-CoA dehydrogenase, C-terminal domain K00249,K11731 - 1.3.8.7 0.0000000000000000003199 87.0
TH2_k127_7827007_2 - - - - 0.000000000000001284 81.0
TH2_k127_7829520_0 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001406 256.0
TH2_k127_7829520_1 Outer membrane protein assembly complex, YaeT protein K07277 - - 0.000002502 61.0
TH2_k127_7836436_0 Belongs to the D-alanine--D-alanine ligase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 537.0
TH2_k127_7836436_1 Belongs to the BI1 family K06890,K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000255 224.0
TH2_k127_7836436_2 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000002423 217.0
TH2_k127_7836436_3 Ferredoxin - - - 0.0000000000000000000000000000000000000000003752 161.0
TH2_k127_7859854_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 368.0
TH2_k127_7859854_1 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 336.0
TH2_k127_7859854_2 - K07275 - - 0.000000000000000000000003284 111.0
TH2_k127_786347_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 512.0
TH2_k127_786347_1 Biogenesis protein K09792 - - 0.00000000000000000000000000000000000001494 155.0
TH2_k127_7869259_0 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 482.0
TH2_k127_7869259_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 481.0
TH2_k127_7869259_2 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 332.0
TH2_k127_7876378_0 penicillin-binding protein K03587 - 3.4.16.4 1.327e-220 703.0
TH2_k127_7876378_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000134 96.0
TH2_k127_7876378_2 Cell division protein FtsL - - - 0.000000000000000000003994 100.0
TH2_k127_7878980_0 PFAM ABC transporter K06861 - - 0.000000000000000004814 85.0
TH2_k127_7878980_1 protein conserved in bacteria - - - 0.0000000000000001288 90.0
TH2_k127_7879249_0 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 390.0
TH2_k127_7879249_2 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000003178 96.0
TH2_k127_7879249_3 response regulator, receiver K01768,K11527,K19617 - 2.7.13.3,4.6.1.1 0.0000000000001414 84.0
TH2_k127_7879249_4 cheY-homologous receiver domain K03413 - - 0.0000000000001523 84.0
TH2_k127_7879249_5 PFAM Lytic transglycosylase catalytic K08309 - - 0.0005002 48.0
TH2_k127_7885008_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.305e-247 772.0
TH2_k127_7885008_1 zinc-ribbon domain - - - 0.0000000000000000000000000000000005695 140.0
TH2_k127_7894357_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 601.0
TH2_k127_7894357_1 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000002312 168.0
TH2_k127_7906627_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.362e-235 737.0
TH2_k127_7906627_1 - - - - 0.0000000000000000000000000000000000000000000000147 174.0
TH2_k127_7915472_0 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 438.0
TH2_k127_7915472_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000001532 214.0
TH2_k127_7915472_2 - - - - 0.0004692 52.0
TH2_k127_7921912_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000672 226.0
TH2_k127_7921912_1 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000002035 88.0
TH2_k127_7921912_2 4'-phosphopantetheinyl transferase superfamily - - - 0.00003674 54.0
TH2_k127_792980_0 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0003971 52.0
TH2_k127_7937818_0 LysM domain protein K07261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002597 254.0
TH2_k127_7937818_1 Cytochrome C oxidase subunit II, periplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005609 239.0
TH2_k127_7937818_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000001724 179.0
TH2_k127_7944517_0 ABC transporter, ATP-binding protein - - - 5.396e-268 846.0
TH2_k127_7944517_1 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000002943 238.0
TH2_k127_7944517_2 Universal stress protein family - - - 0.00000000000000000000001056 106.0
TH2_k127_7944517_3 Universal stress protein family - - - 0.000000009988 59.0
TH2_k127_7955865_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.627e-208 654.0
TH2_k127_7955865_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 339.0
TH2_k127_7955865_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002122 296.0
TH2_k127_7960698_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 365.0
TH2_k127_7960698_1 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002254 288.0
TH2_k127_7960698_2 - - - - 0.000000000000000000000000000000000000000009614 170.0
TH2_k127_7960698_3 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000004706 110.0
TH2_k127_7960698_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000001356 61.0
TH2_k127_7991545_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 591.0
TH2_k127_7991545_1 metallopeptidase activity K06974 - - 0.000000000000000000000000000000005774 139.0
TH2_k127_7991545_2 NlpC/P60 family - - - 0.00002871 54.0
TH2_k127_8008944_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 6.597e-213 674.0
TH2_k127_8008944_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 316.0
TH2_k127_8012060_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 436.0
TH2_k127_8012060_1 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002487 280.0
TH2_k127_8012060_2 peptidase M48, Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000001857 230.0
TH2_k127_8012060_3 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000004505 113.0
TH2_k127_8012060_4 Outer membrane efflux protein K15725 - - 0.0002032 50.0
TH2_k127_8016620_2 Putative metal-binding motif - - - 0.000000000000000109 94.0
TH2_k127_8016620_3 - - - - 0.000000000000006584 81.0
TH2_k127_8016620_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000007563 80.0
TH2_k127_8016620_5 Protein of unknown function (DUF4239) - - - 0.00000001333 66.0
TH2_k127_8016620_6 protein trimerization - - - 0.0001095 54.0
TH2_k127_8016620_7 cellulose binding K07279 - - 0.0004226 45.0
TH2_k127_8020636_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 485.0
TH2_k127_8020636_1 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 354.0
TH2_k127_8020636_2 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 309.0
TH2_k127_8020636_3 oligopeptide transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002673 273.0
TH2_k127_8020636_4 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000005433 231.0
TH2_k127_8020636_5 Fibronectin type 3 domain - - - 0.000000000000000000000000000001977 139.0
TH2_k127_8052262_0 Pilus formation protein N terminal region K02280 - - 3.375e-250 781.0
TH2_k127_8052262_1 Type II IV secretion system protein K02283,K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 370.0
TH2_k127_8052262_2 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000003498 220.0
TH2_k127_8052262_3 Type IV leader peptidase family K02278 - 3.4.23.43 0.0000000000000000000000000000000000000000002892 165.0
TH2_k127_8056217_2 Transglutaminase-like superfamily - - - 0.000000000000000003866 88.0
TH2_k127_8056217_3 domain protein - - - 0.00000000000000003004 89.0
TH2_k127_8056217_4 - - - - 0.000000000000001207 88.0
TH2_k127_8056217_5 Histidine Phosphotransfer domain - - - 0.000000000002198 74.0
TH2_k127_8056422_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 547.0
TH2_k127_8056422_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009964 321.0
TH2_k127_8071463_0 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000008455 225.0
TH2_k127_8071463_2 - - - - 0.0000002593 59.0
TH2_k127_8077595_0 Lactonase, 7-bladed beta-propeller - - - 0.000929 53.0
TH2_k127_8078194_0 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 623.0
TH2_k127_8078194_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001417 266.0
TH2_k127_8078194_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000001534 242.0
TH2_k127_8078194_3 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000008937 230.0
TH2_k127_8078194_4 Nudix hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000586 199.0
TH2_k127_8078194_5 Tetratricopeptide repeat - - - 0.000000000000000000000001036 109.0
TH2_k127_8080566_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 496.0
TH2_k127_8082107_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 566.0
TH2_k127_8082107_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 409.0
TH2_k127_8082107_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 312.0
TH2_k127_8082107_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 300.0
TH2_k127_8082107_4 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000004295 137.0
TH2_k127_8082107_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000004084 101.0
TH2_k127_8118650_0 Putative metal-binding motif - - - 0.000000000001669 81.0
TH2_k127_8131857_0 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003921 274.0
TH2_k127_8131857_1 Reverse transcriptase-like K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001568 262.0
TH2_k127_8131857_2 Protein of unknown function (FYDLN_acid) - - - 0.0000000000000000000000009184 107.0
TH2_k127_8131857_4 - - - - 0.0000002889 53.0
TH2_k127_8134372_0 Phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004986 263.0
TH2_k127_8134372_1 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.000000005486 64.0
TH2_k127_8142410_0 Aerotolerance regulator N-terminal - - - 1.414e-198 646.0
TH2_k127_8142410_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 413.0
TH2_k127_8142410_2 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000001686 175.0
TH2_k127_8142529_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 330.0
TH2_k127_8142529_1 Fungalysin metallopeptidase (M36) - - - 0.00000000000000000000000006149 115.0
TH2_k127_8142529_2 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.00000001028 58.0
TH2_k127_8147570_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000994 203.0
TH2_k127_8151099_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000002178 236.0
TH2_k127_8151099_1 Thioredoxin-like domain - - - 0.00000000000000000000000000000000000000000008265 167.0
TH2_k127_8151099_2 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.0000000000000003822 81.0
TH2_k127_8151099_3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin - - - 0.000000000001475 81.0
TH2_k127_8151099_4 Protein of unknown function (DUF1573) - - - 0.000003987 58.0
TH2_k127_8157901_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 556.0
TH2_k127_8157901_1 phosphoglycolate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 297.0
TH2_k127_8157901_2 Major Facilitator Superfamily K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 287.0
TH2_k127_8157901_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000005704 193.0
TH2_k127_8177298_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.664e-225 705.0
TH2_k127_8177298_1 Methyltransferase type 11 K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000233 264.0
TH2_k127_8177298_2 Stigma-specific protein, Stig1 - - - 0.0000000000000000000000000000000005255 151.0
TH2_k127_8185478_0 Peptidase M16 - - - 0.0 1025.0
TH2_k127_8185478_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001416 265.0
TH2_k127_8185478_2 domain protein - - - 0.0000000000000000000000000001352 119.0
TH2_k127_8185478_3 HEAT repeat - - - 0.0008917 49.0
TH2_k127_820113_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000003298 208.0
TH2_k127_820113_1 - - - - 0.0000000000000000000000000000000000000000000000000000000002747 206.0
TH2_k127_820113_2 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.0000000000000000000000000000000000000000000000001594 179.0
TH2_k127_820113_3 FlhB HrpN YscU SpaS Family K02401,K04061 - - 0.0000000000000000000000000000000000002664 142.0
TH2_k127_8209272_0 Periplasmic protein TonB links inner and outer membranes - - - 0.000000000000000000000000000000000000000000000000000000000000001393 231.0
TH2_k127_8231155_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 481.0
TH2_k127_8231155_1 Castor and Pollux, part of voltage-gated ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 383.0
TH2_k127_8231155_2 May be involved in the biosynthesis of molybdopterin K03638,K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001128 269.0
TH2_k127_8231155_3 Staphylococcal nuclease homologue - - - 0.0000000000000000000000000000000000000000000000000000000000001223 222.0
TH2_k127_8231155_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000002103 201.0
TH2_k127_8231155_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000009433 145.0
TH2_k127_8231155_6 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000953 129.0
TH2_k127_8239108_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 294.0
TH2_k127_8239108_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000114 273.0
TH2_k127_8251476_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.638e-233 728.0
TH2_k127_8251476_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.964e-233 728.0
TH2_k127_8251476_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 473.0
TH2_k127_8251476_4 PFAM SNARE associated Golgi protein - - - 0.0000000000005623 77.0
TH2_k127_8251476_5 TM2 domain - - - 0.0000006511 57.0
TH2_k127_8266874_0 transcriptional regulator, MerR family K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006463 278.0
TH2_k127_8266874_1 Belongs to the DNA photolyase family K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001711 262.0
TH2_k127_8266874_2 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008016 264.0
TH2_k127_8266874_3 transferase activity, transferring glycosyl groups K00720 - 2.4.1.80 0.00000000000000000000001881 104.0
TH2_k127_8266874_4 Thioredoxin-like protein AAED1 - GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009636,GO:0009987,GO:0016209,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000004033 113.0
TH2_k127_8278748_0 COG1233 Phytoene dehydrogenase and related proteins K09835 - 5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 290.0
TH2_k127_8278748_1 Bacterial protein of unknown function (YtfJ_HI0045) K07109 - - 0.0000000000000000000000000001737 122.0
TH2_k127_8291140_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 7.838e-195 620.0
TH2_k127_8291140_1 Surface antigen K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 601.0
TH2_k127_8291140_2 Putative metal-binding motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002416 293.0
TH2_k127_8291140_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001164 244.0
TH2_k127_8291140_4 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000007951 215.0
TH2_k127_8291140_5 Putative zinc-finger - - - 0.0000000000000000000000005632 105.0
TH2_k127_8291140_6 Putative metal-binding motif - - - 0.0000000000000005845 94.0
TH2_k127_8291140_7 Alpha/beta hydrolase family - - - 0.00000000002397 74.0
TH2_k127_8291140_8 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000007115 76.0
TH2_k127_8299400_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 388.0
TH2_k127_8299400_1 domain, Protein K20276 - - 0.000000000000000000003563 111.0
TH2_k127_8299400_2 Bacterial Ig-like domain (group 3) - - - 0.00000000000000005336 98.0
TH2_k127_8299400_3 Ankyrin repeat - - - 0.000002039 63.0
TH2_k127_8303625_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 413.0
TH2_k127_8304932_0 - - - - 0.0000000000000000005125 102.0
TH2_k127_8307663_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1381.0
TH2_k127_8307663_1 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 329.0
TH2_k127_8307663_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 304.0
TH2_k127_8308742_0 Squalene-hopene cyclase N-terminal domain K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 2.31e-211 683.0
TH2_k127_8308742_1 Squalene/phytoene synthase K00801 - 2.5.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000002588 257.0
TH2_k127_8308742_2 Methyltransferase - - - 0.000000000000000000000041 105.0
TH2_k127_8309621_1 cAMP biosynthetic process - - - 0.000000000009505 77.0
TH2_k127_8309821_2 COG4584 Transposase and inactivated derivatives - - - 0.0000004369 60.0
TH2_k127_8309821_3 guanyl-nucleotide exchange factor activity K19231,K21449 - - 0.00007841 55.0
TH2_k127_8313342_0 - - - - 0.000000000000000000000000000000000001104 154.0
TH2_k127_8313342_1 His Kinase A (phosphoacceptor) domain - - - 0.0000001181 67.0
TH2_k127_8313342_2 cAMP biosynthetic process - - - 0.00000291 61.0
TH2_k127_8313342_3 guanyl-nucleotide exchange factor activity K14475,K20276 - - 0.00004951 58.0
TH2_k127_8320882_0 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 361.0
TH2_k127_8320882_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000005122 194.0
TH2_k127_8321408_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008774 285.0
TH2_k127_8321408_1 Thrombospondin type 3 repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001199 263.0
TH2_k127_8321408_11 Tetratricopeptide repeats - - - 0.000003951 54.0
TH2_k127_8321408_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000406 240.0
TH2_k127_8321408_3 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000006762 154.0
TH2_k127_8321408_4 Thioesterase superfamily - - - 0.000000000000000000000000000000000001276 144.0
TH2_k127_8321408_5 Endonuclease Exonuclease Phosphatase K01179,K07004 - 3.2.1.4 0.00000000000000000000000000001791 136.0
TH2_k127_8321408_6 - - - - 0.0000000000000000000000001686 110.0
TH2_k127_8321408_7 - - - - 0.000000000000003199 82.0
TH2_k127_8321408_8 Putative metal-binding motif - - - 0.000000000001032 81.0
TH2_k127_8321408_9 - - - - 0.00000003198 66.0
TH2_k127_8329377_0 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 355.0
TH2_k127_8329377_1 - - - - 0.000009884 58.0
TH2_k127_8355867_0 alginic acid biosynthetic process K01729 - 4.2.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 612.0
TH2_k127_8355867_1 Butirosin biosynthesis protein H, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 299.0
TH2_k127_8355867_2 PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002274 280.0
TH2_k127_8355867_3 Belongs to the beta-ketoacyl-ACP synthases family - - - 0.000000000000000000000000000000000000000000000796 181.0
TH2_k127_8355867_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000007033 175.0
TH2_k127_8355867_5 beta-ketoacyl-acyl-carrier-protein synthase II activity - - - 0.0000000000000000413 96.0
TH2_k127_8355867_6 - - - - 0.00000000000002166 82.0
TH2_k127_8355867_7 Phosphopantetheine attachment site K02078 - - 0.000000000001366 71.0
TH2_k127_8372913_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 584.0
TH2_k127_8372913_1 COG1073 hydrolases of the alpha beta superfamily - - - 0.000000000000000996 83.0
TH2_k127_8386013_0 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 293.0
TH2_k127_838696_0 uridine kinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 309.0
TH2_k127_838696_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000003594 201.0
TH2_k127_838696_2 Nucleotidyl transferase - - - 0.0000000000000000000006756 101.0
TH2_k127_8392629_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000001956 236.0
TH2_k127_8392629_1 TatD related DNase K07051 - - 0.0000000000000000000000005858 108.0
TH2_k127_8399273_0 Pfam Transposase IS66 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002194 287.0
TH2_k127_8399273_1 FMN binding - - - 0.0000000000000000000000000000000000000000002541 164.0
TH2_k127_8418829_0 VWA domain containing CoxE-like protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 500.0
TH2_k127_8418829_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 434.0
TH2_k127_8418829_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000001593 265.0
TH2_k127_8418829_3 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000002058 205.0
TH2_k127_8418829_4 - - - - 0.00000000000000000000000000000000000000000000001141 181.0
TH2_k127_8418829_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000768 145.0
TH2_k127_8424767_0 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 434.0
TH2_k127_8424767_1 - - - - 0.00000000000000000000000000001006 137.0
TH2_k127_8424767_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0002699 44.0
TH2_k127_8429518_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 605.0
TH2_k127_8429518_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 328.0
TH2_k127_8429518_2 helix_turn_helix, mercury resistance K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 305.0
TH2_k127_8429518_3 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.00000000000000000000000000000000000000000001324 184.0
TH2_k127_8431109_0 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000001168 197.0
TH2_k127_8431109_1 Protein of unknown function (DUF3106) - - - 0.00000001613 60.0
TH2_k127_8431109_2 acetyltransferase - - - 0.0000884 52.0
TH2_k127_8442758_0 AMP-binding enzyme - - - 4.439e-229 730.0
TH2_k127_8442758_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 503.0
TH2_k127_8442758_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000005527 260.0
TH2_k127_8442758_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000000000009619 273.0
TH2_k127_8442758_4 domain, Protein - - - 0.000000000000000000000000004251 118.0
TH2_k127_8442758_5 TIGRFAM repeat-companion domain TIGR02996 - - - 0.000000006526 68.0
TH2_k127_8442758_6 - - - - 0.0001842 55.0
TH2_k127_8457490_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002931 292.0
TH2_k127_8475931_0 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008593 372.0
TH2_k127_8475931_1 NADH ubiquinone oxidoreductase subunit 11 or 4L (Chain K) K00340 - 1.6.5.3 0.000000000000000005571 93.0
TH2_k127_8475931_2 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000007149 81.0
TH2_k127_8479687_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 4.691e-206 646.0
TH2_k127_8479687_1 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 319.0
TH2_k127_8479687_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001828 139.0
TH2_k127_8484319_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 439.0
TH2_k127_8484319_1 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002795 268.0
TH2_k127_8484319_2 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000461 209.0
TH2_k127_8484319_3 Methyltransferase domain - - - 0.000000000000000000000000008631 111.0
TH2_k127_8484319_4 - - - - 0.00000000000000004833 94.0
TH2_k127_8484319_5 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.000000001567 71.0
TH2_k127_8484319_6 Cyclic nucleotide-monophosphate binding domain - - - 0.0001043 55.0
TH2_k127_8487632_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001926 273.0
TH2_k127_8487632_2 Tetratricopeptide repeat - - - 0.000004756 56.0
TH2_k127_8492662_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 597.0
TH2_k127_8492662_1 Peptidase C14, caspase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 304.0
TH2_k127_8492662_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000001468 165.0
TH2_k127_8492662_3 AntiSigma factor - - - 0.000000000000000000000000006702 126.0
TH2_k127_8492662_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000001023 56.0
TH2_k127_8497802_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000008036 249.0
TH2_k127_8497802_1 D-alanyl-D-alanine carboxypeptidase K17733 - - 0.0000000000000000000000003588 120.0
TH2_k127_8499971_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 526.0
TH2_k127_8499971_1 - - - - 0.000000000000000000000000001881 116.0
TH2_k127_8499971_2 protein secretion by the type VII secretion system K11904,K21493 - - 0.00000000000000000000000001094 123.0
TH2_k127_8499971_3 - - - - 0.00000000000000000000001889 115.0
TH2_k127_8499971_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000002066 81.0
TH2_k127_8499971_5 Fe-S-cluster oxidoreductase - - - 0.000000000003898 76.0
TH2_k127_8499971_6 integral membrane protein - - - 0.0000002152 61.0
TH2_k127_8505442_0 PEGA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 479.0
TH2_k127_8505442_1 EamA-like transporter family - - - 0.00000000009022 66.0
TH2_k127_8505723_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000003029 150.0
TH2_k127_8509423_0 OmpA family - - - 6.093e-203 650.0
TH2_k127_8509423_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 345.0
TH2_k127_8511174_0 Forkhead associated domain - - - 6.547e-194 623.0
TH2_k127_8511174_1 alcohol dehydrogenase K18012 - 1.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 481.0
TH2_k127_8511174_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 457.0
TH2_k127_8511174_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 359.0
TH2_k127_8511174_5 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 0.000000000000000000000000000000000000000001268 157.0
TH2_k127_8511174_6 - - - - 0.00000000000000000000000000002788 121.0
TH2_k127_853570_0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001072 250.0
TH2_k127_853570_1 4Fe-4S dicluster domain K17723 - 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001528 236.0
TH2_k127_8541451_0 PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002125 311.0
TH2_k127_8541451_1 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000149 233.0
TH2_k127_8541451_2 phosphate-selective porin O and P - - - 0.00007712 55.0
TH2_k127_8542384_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 8.098e-205 649.0
TH2_k127_8542384_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 336.0
TH2_k127_8542384_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000006382 216.0
TH2_k127_8542384_3 histone H2A K63-linked ubiquitination K08777 - - 0.00000000000000000000000000000000001845 153.0
TH2_k127_8550209_0 Oligoendopeptidase f - - - 7.868e-283 880.0
TH2_k127_8552075_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 6.262e-212 675.0
TH2_k127_8561883_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 453.0
TH2_k127_8561883_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 344.0
TH2_k127_8561883_2 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 301.0
TH2_k127_8561883_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001076 267.0
TH2_k127_8561883_4 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001242 253.0
TH2_k127_8561883_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001953 205.0
TH2_k127_8561883_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000002531 179.0
TH2_k127_8561883_7 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001206 102.0
TH2_k127_8563242_0 CoA-transferase family III K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 507.0
TH2_k127_8563242_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 360.0
TH2_k127_8563242_2 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000000000000001214 165.0
TH2_k127_8578524_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 9.27e-282 883.0
TH2_k127_8578524_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 409.0
TH2_k127_8578524_3 - - - - 0.00000000000000000000000000000000000002034 153.0
TH2_k127_8579024_0 Nitrous oxide reductase K00376 - 1.7.2.4 3.84e-253 798.0
TH2_k127_8579024_1 periplasmic copper-binding protein NosD K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008991 259.0
TH2_k127_8579024_2 abc transporter atp-binding protein K01990 - - 0.0000000000000000000000000000000000000001739 157.0
TH2_k127_859034_0 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 430.0
TH2_k127_859034_1 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 374.0
TH2_k127_859034_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000678 263.0
TH2_k127_859034_3 Biotin-requiring enzyme K02160 - - 0.0000000005422 59.0
TH2_k127_8612012_0 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000001073 205.0
TH2_k127_8612012_1 - - - - 0.00000000000000000000000000000000000000000000004497 178.0
TH2_k127_8612012_2 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000000000000000001454 162.0
TH2_k127_8616501_0 UPF0313 protein - - - 0.0 1037.0
TH2_k127_8616501_1 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000006986 125.0
TH2_k127_8633425_0 topoisomerase K02469 - 5.99.1.3 0.0 1084.0
TH2_k127_8639088_0 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 368.0
TH2_k127_8639088_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 321.0
TH2_k127_8639088_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000001618 130.0
TH2_k127_8639088_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000003153 87.0
TH2_k127_8639088_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000001607 83.0
TH2_k127_8640994_0 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 466.0
TH2_k127_8640994_1 Acetyltransferase (GNAT) family - - - 0.0000000000000000000003473 102.0
TH2_k127_8640994_2 - - - - 0.0000006786 58.0
TH2_k127_8647314_0 Aldehyde dehydrogenase family K04021 - - 1.099e-216 681.0
TH2_k127_8647314_1 BMC - - - 0.0000000000000000000000000000000000000000000000000000006782 194.0
TH2_k127_8647314_2 BMC K04027 - - 0.00000000000000000000000000000000000000000004515 162.0
TH2_k127_8647314_3 BMC - - - 0.000000000000000000000000000000000000000005974 160.0
TH2_k127_8647314_4 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000000000000000000006459 135.0
TH2_k127_8658044_0 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000009448 233.0
TH2_k127_8658044_1 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000006874 147.0
TH2_k127_8658044_2 COG0695 glutaredoxin and related proteins - - - 0.0000000000000000000000000000007063 130.0
TH2_k127_8658044_3 COG0695 glutaredoxin and related proteins - - - 0.000000000000000000000000003271 111.0
TH2_k127_8666036_0 polyphosphate kinase - - - 3.245e-200 641.0
TH2_k127_8666036_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 417.0
TH2_k127_8666036_2 PilT protein domain protein - - - 0.000000000000000000000000000000004735 149.0
TH2_k127_8679610_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 597.0
TH2_k127_8679610_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002016 233.0
TH2_k127_8679610_2 ATPase activity - - - 0.000000000000000000000000000000000000000000000000000656 194.0
TH2_k127_8679610_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000002394 91.0
TH2_k127_8680628_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 4.596e-228 713.0
TH2_k127_8680628_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 386.0
TH2_k127_8680628_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003759 276.0
TH2_k127_8680628_3 Alpha beta hydrolase - - - 0.0000000000000000000005775 106.0
TH2_k127_8680628_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000001124 62.0
TH2_k127_868683_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000001243 209.0
TH2_k127_868683_1 Chaperone - - - 0.0000178 57.0
TH2_k127_8690274_0 Band 7 protein K07192 - - 5.508e-260 819.0
TH2_k127_8690274_1 ATPase involved in DNA repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 361.0
TH2_k127_8690274_2 - - - - 0.0000000000000000000000000000001638 131.0
TH2_k127_8701268_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000001898 149.0
TH2_k127_8705920_0 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 295.0
TH2_k127_8705920_1 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008591 288.0
TH2_k127_8705920_2 ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000000000001519 217.0
TH2_k127_8705920_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000001575 220.0
TH2_k127_8705920_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000002743 66.0
TH2_k127_871028_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003963 232.0
TH2_k127_871028_1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000003877 197.0
TH2_k127_871028_2 UbiA prenyltransferase family - - - 0.0000000000000000000000000000001972 126.0
TH2_k127_8738592_0 Pectinacetylesterase - - - 0.0000000000000000000000000000000000000000001294 172.0
TH2_k127_8750574_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000009102 253.0
TH2_k127_8750574_1 radical SAM domain protein - - - 0.0000000000000000001624 104.0
TH2_k127_8768207_0 PLD-like domain - - - 0.00000000000000000000000000000000000000000002202 176.0
TH2_k127_8768207_1 Hemerythrin HHE cation binding domain - - - 0.00000000004367 72.0
TH2_k127_8778296_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 364.0
TH2_k127_8778296_1 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.0000000000000000000000000000000000000000000000000000000000000000002262 252.0
TH2_k127_8778296_3 Methyltransferase domain - - - 0.000000000008448 66.0
TH2_k127_8779375_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 537.0
TH2_k127_8779375_1 COG0208 Ribonucleotide reductase, beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 496.0
TH2_k127_8779375_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 475.0
TH2_k127_8779375_3 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000008122 233.0
TH2_k127_8779375_4 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000000002732 197.0
TH2_k127_8779375_5 YsiA-like protein, C-terminal region - - - 0.0000000000000000000000000000000000000000004589 166.0
TH2_k127_8785722_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 371.0
TH2_k127_8785722_1 Uracil DNA glycosylase superfamily K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 289.0
TH2_k127_8787339_0 Zinc-dependent metalloprotease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002298 263.0
TH2_k127_8787339_1 Zinc-dependent metalloprotease - - - 0.00000000000000000000000000000000000000000000000000000000000000000002562 252.0
TH2_k127_8787339_2 - - - - 0.000000000000000000000000000000000007848 145.0
TH2_k127_8801453_0 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 471.0
TH2_k127_8801453_1 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 336.0
TH2_k127_8801453_2 Carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000004452 215.0
TH2_k127_8801453_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000005376 107.0
TH2_k127_8801453_4 - - - - 0.000000000000000000000001318 108.0
TH2_k127_8801453_5 - - - - 0.0000001772 54.0
TH2_k127_8801453_6 repeat-containing protein - - - 0.000005234 56.0
TH2_k127_880617_0 RHS Repeat - - - 0.00001166 59.0
TH2_k127_880617_1 CARDB - - - 0.0006236 53.0
TH2_k127_8811331_0 Superfamily II DNA RNA helicases, SNF2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 509.0
TH2_k127_8811331_1 xanthine dehydrogenase activity K04108 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 334.0
TH2_k127_8811331_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001146 250.0
TH2_k127_8811331_3 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000407 197.0
TH2_k127_8811981_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 428.0
TH2_k127_8811981_1 TrkA-N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006906 286.0
TH2_k127_8811981_2 Flavodoxin-like fold K11748 - - 0.0000000000000000000000000000000000000000000000000000000000004394 218.0
TH2_k127_8814649_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 507.0
TH2_k127_8814649_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007379 271.0
TH2_k127_8814649_2 domain, Protein - - - 0.0000009238 63.0
TH2_k127_8816460_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 392.0
TH2_k127_8816460_1 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000001606 208.0
TH2_k127_8816460_2 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000001742 100.0
TH2_k127_8819447_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006734 259.0
TH2_k127_8819447_1 ThiS family K03636 - - 0.000002018 52.0
TH2_k127_8819447_2 S-layer homology domain - - - 0.0005755 51.0
TH2_k127_8821416_0 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000742 181.0
TH2_k127_8821416_1 CBS domain K04767 - - 0.00000000000000002042 89.0
TH2_k127_8824102_0 ABC transporter, (ATP-binding protein) K02021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 418.0
TH2_k127_8828069_0 PHP domain protein - - - 0.0 1034.0
TH2_k127_8828069_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 334.0
TH2_k127_8828069_2 Lamin Tail Domain - - - 0.000000000000000000000000005966 129.0
TH2_k127_8828069_3 Belongs to the peptidase S8 family K13276 - - 0.000000000000000004525 100.0
TH2_k127_8831235_0 A-macroglobulin complement component - - - 0.0 1503.0
TH2_k127_8831235_1 Proprotein convertase P-domain - - - 0.0004094 51.0
TH2_k127_8842397_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 3.789e-217 695.0
TH2_k127_8842397_1 peptidyl-tyrosine sulfation - - - 0.00009747 47.0
TH2_k127_8847205_0 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 4.857e-262 814.0
TH2_k127_8847205_1 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 317.0
TH2_k127_8857728_0 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006321 278.0
TH2_k127_8862825_0 cellulose binding - - - 0.000000000000002024 91.0
TH2_k127_8872340_0 DNA helicase K03657 - 3.6.4.12 1.99e-272 857.0
TH2_k127_8872340_1 Glycosyl transferases group 1 K12989 - - 0.0000000000000000000000000000000000000000000000000002311 196.0
TH2_k127_8872340_2 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.000000000000000000000000000000000000000000000001325 186.0
TH2_k127_8872634_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 529.0
TH2_k127_8872634_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000005292 211.0
TH2_k127_8898864_0 FHA domain - - - 0.0000000000000000007696 93.0
TH2_k127_8899980_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 467.0
TH2_k127_8899980_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000002927 185.0
TH2_k127_8899980_2 alpha beta - - - 0.00000000000000000223 100.0
TH2_k127_8899980_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - 0.00000003978 54.0
TH2_k127_914839_0 MFS/sugar transport protein K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001221 296.0
TH2_k127_914839_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004326 250.0
TH2_k127_914839_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000003847 151.0
TH2_k127_914839_3 - - - - 0.000000004702 67.0
TH2_k127_914839_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000005513 51.0
TH2_k127_915823_0 Beta-ketoacyl synthase K14371 - - 0.000004166 60.0
TH2_k127_917644_0 PFAM TadE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 329.0
TH2_k127_917644_1 TadE-like protein - - - 0.00000000000000000000000000000000000000000000000000001976 198.0
TH2_k127_917809_0 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 359.0
TH2_k127_917809_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000007448 80.0
TH2_k127_918414_0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 396.0
TH2_k127_918414_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000001949 195.0
TH2_k127_918414_2 Methyltransferase - - - 0.000000000000000000000000000000000000000002288 164.0
TH2_k127_918414_3 cellulose binding - - - 0.00000000000000000000000000000000000004345 155.0
TH2_k127_918414_5 PilZ domain - - - 0.0000000000000000000001754 101.0
TH2_k127_92106_0 membrane protein involved in D-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 317.0
TH2_k127_92106_1 Transcription elongation factor, GreA/GreB, C-term - - - 0.0000000000000000000000000000000009059 136.0
TH2_k127_936933_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0 1491.0
TH2_k127_936933_1 oxidoreductase activity K16260 - - 0.00000000000000003493 92.0
TH2_k127_936933_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0001681 52.0
TH2_k127_943020_0 amine dehydrogenase activity - - - 0.000005264 58.0
TH2_k127_947250_0 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000109 274.0
TH2_k127_947250_1 Protein of unknown function (DUF1460) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005778 248.0
TH2_k127_947250_2 - - - - 0.0008789 47.0
TH2_k127_952574_0 Putative RNA methylase family UPF0020 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 453.0
TH2_k127_952574_1 - - - - 0.000000000000000003512 94.0
TH2_k127_972465_0 Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 531.0
TH2_k127_972465_1 protein with SCP PR1 domains - - - 0.0000000000000000168 94.0
TH2_k127_972465_2 Parallel beta-helix repeats - - - 0.0005671 53.0