Overview

ID MAG03906
Name TH2_bin.34
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA6898
Genus UBA6898
Species
Assembly information
Completeness (%) 76.29
Contamination (%) 3.8
GC content (%) 53.0
N50 (bp) 11,648
Genome size (bp) 1,784,974

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1764

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_101041_0 Ammonium Transporter K03320 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 569.0
TH2_k127_101041_1 - - - - 0.00000000000000000000000000000000000000001273 163.0
TH2_k127_101041_2 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000001079 126.0
TH2_k127_101041_3 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000005857 58.0
TH2_k127_103824_0 CO-methylating acetyl-CoA synthase activity K00193,K14138 - 2.3.1.169 7.564e-214 671.0
TH2_k127_103824_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 598.0
TH2_k127_104504_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1201.0
TH2_k127_104504_1 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 601.0
TH2_k127_104504_2 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 456.0
TH2_k127_104504_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 329.0
TH2_k127_104504_4 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 300.0
TH2_k127_104504_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000001192 256.0
TH2_k127_104504_6 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000001119 114.0
TH2_k127_105109_0 PFAM ATPase BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 396.0
TH2_k127_105109_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 340.0
TH2_k127_105109_2 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000751 299.0
TH2_k127_105109_3 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000002248 223.0
TH2_k127_105109_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000155 70.0
TH2_k127_108489_0 - - - - 0.000000000000003509 83.0
TH2_k127_108489_1 - K07071 - - 0.0000000007844 62.0
TH2_k127_1092908_0 PFAM Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001264 255.0
TH2_k127_1131295_0 Transposase, Mutator family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 420.0
TH2_k127_1131295_1 Transposase - - - 0.0000000000000000000000000000000000000000000000000000001121 201.0
TH2_k127_1131295_2 DDE superfamily endonuclease K07494 - - 0.000000002312 59.0
TH2_k127_1133521_0 Cytochrome c554 and c-prime - - - 0.0 1104.0
TH2_k127_1133521_1 arylsulfatase A K01130 - 3.1.6.1 1.424e-284 880.0
TH2_k127_1133521_10 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000001808 98.0
TH2_k127_1133521_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000000000000001172 220.0
TH2_k127_1133521_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000000000000000433 211.0
TH2_k127_1133521_4 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000006681 196.0
TH2_k127_1133521_5 PIN domain - - - 0.00000000000000000000000000000000000007659 145.0
TH2_k127_1133521_6 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000002008 154.0
TH2_k127_1133521_7 oxidation-reduction process - - - 0.000000000000000000000000000000008747 137.0
TH2_k127_1133521_9 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000000000003196 106.0
TH2_k127_1211248_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 428.0
TH2_k127_1211248_1 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 383.0
TH2_k127_1211248_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 307.0
TH2_k127_1211248_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 290.0
TH2_k127_1211248_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000001066 244.0
TH2_k127_1211248_5 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000003828 129.0
TH2_k127_1220922_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1347.0
TH2_k127_1220922_1 Histidine kinase K07642,K18143 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 374.0
TH2_k127_1220922_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 301.0
TH2_k127_1220922_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 307.0
TH2_k127_1220922_4 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000008977 111.0
TH2_k127_1274622_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 448.0
TH2_k127_1274622_1 Multicopper oxidase K22349 - 1.16.3.3 0.000000000000000141 83.0
TH2_k127_1277553_0 Macro domain K15529 - 3.1.3.84 0.0000000000000000000002179 102.0
TH2_k127_1281557_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 6.661e-269 839.0
TH2_k127_1281557_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 556.0
TH2_k127_1281557_10 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000368 134.0
TH2_k127_1281557_11 DRTGG domain - - - 0.000000000000000000000000000000018 129.0
TH2_k127_1281557_12 phosphorelay signal transduction system K02437 - - 0.0000000000000000000000000001469 125.0
TH2_k127_1281557_13 DRTGG domain - - - 0.00000000000000000000000008645 113.0
TH2_k127_1281557_14 PFAM PHP domain K07053 - 3.1.3.97 0.000000000000006196 76.0
TH2_k127_1281557_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000001109 71.0
TH2_k127_1281557_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 488.0
TH2_k127_1281557_3 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 351.0
TH2_k127_1281557_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000009235 199.0
TH2_k127_1281557_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001634 202.0
TH2_k127_1281557_6 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.00000000000000000000000000000000000000000000000007803 189.0
TH2_k127_1281557_7 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.0000000000000000000000000000000000000002957 153.0
TH2_k127_1281557_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000006997 145.0
TH2_k127_1281557_9 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000000001496 142.0
TH2_k127_1311114_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 2.12e-255 798.0
TH2_k127_1311114_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 367.0
TH2_k127_1311114_2 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 347.0
TH2_k127_1311114_3 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 302.0
TH2_k127_1311114_4 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000008315 250.0
TH2_k127_1311114_5 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000003066 179.0
TH2_k127_1311114_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.0000000000000000000000002814 107.0
TH2_k127_1311114_7 exodeoxyribonuclease I activity - - - 0.00000376 54.0
TH2_k127_1321939_0 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 409.0
TH2_k127_1321939_1 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 320.0
TH2_k127_1321939_2 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.000000000000000000000000000001506 120.0
TH2_k127_1338729_0 anaerobic respiration - - - 0.000000000000000000000000000000001078 141.0
TH2_k127_1338729_1 electron transfer activity K02305,K08738 - - 0.0000000000000000000000001316 113.0
TH2_k127_1338729_2 Transposase (IS116 IS110 IS902 family) - - - 0.000001686 51.0
TH2_k127_1338729_3 - - - - 0.00006446 52.0
TH2_k127_1352637_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 532.0
TH2_k127_1352637_1 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 460.0
TH2_k127_1352637_10 NTPase - - - 0.000000000000000000000000000000000000000002592 162.0
TH2_k127_1352637_11 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000000006836 92.0
TH2_k127_1352637_12 Uncharacterised protein family (UPF0158) - - - 0.000000007252 65.0
TH2_k127_1352637_13 iron-sulfur cluster assembly - - - 0.0001562 45.0
TH2_k127_1352637_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 416.0
TH2_k127_1352637_3 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 402.0
TH2_k127_1352637_4 PFAM Cys Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 374.0
TH2_k127_1352637_5 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 331.0
TH2_k127_1352637_6 membrane K09133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 330.0
TH2_k127_1352637_7 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000005784 234.0
TH2_k127_1352637_8 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000002255 198.0
TH2_k127_1352637_9 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000007422 164.0
TH2_k127_1357702_0 Transposase - - - 0.0000000000000000000000000000000000000000000000001173 181.0
TH2_k127_1366773_0 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 400.0
TH2_k127_1366773_1 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000000000000008681 122.0
TH2_k127_1366773_2 nuclease activity K06218 - - 0.00000000000000000000004769 100.0
TH2_k127_13744_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.048e-254 797.0
TH2_k127_13744_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 531.0
TH2_k127_13744_10 - - - - 0.000000000000000000000000000000000000000000000000000119 191.0
TH2_k127_13744_11 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000000000002451 188.0
TH2_k127_13744_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000002383 196.0
TH2_k127_13744_13 His Kinase A (phosphoacceptor) domain K14982 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000001103 139.0
TH2_k127_13744_14 cheY-homologous receiver domain - - - 0.00000000000000000000000004697 111.0
TH2_k127_13744_15 Histidine kinase - - - 0.00000000000000005296 87.0
TH2_k127_13744_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 368.0
TH2_k127_13744_3 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 366.0
TH2_k127_13744_4 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 373.0
TH2_k127_13744_5 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 314.0
TH2_k127_13744_6 PFAM Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 298.0
TH2_k127_13744_7 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 256.0
TH2_k127_13744_8 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.0000000000000000000000000000000000000000000000000000000000003771 217.0
TH2_k127_13744_9 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000006078 198.0
TH2_k127_1379420_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 1952.0
TH2_k127_1379420_1 COG2223 Nitrate nitrite transporter K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 546.0
TH2_k127_1379420_10 Nitrate reductase, beta subunit K00371,K17051 - 1.7.5.1 0.000000000000004927 75.0
TH2_k127_1379420_2 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 422.0
TH2_k127_1379420_3 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000005003 254.0
TH2_k127_1379420_4 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000001055 246.0
TH2_k127_1379420_5 PFAM Cyclic nucleotide-binding K10914,K21563 - - 0.00000000000000000000000000002833 126.0
TH2_k127_1379420_6 cytochrome c - - - 0.0000000000000000000000000001558 122.0
TH2_k127_1379420_7 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000003083 118.0
TH2_k127_1379420_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000005366 115.0
TH2_k127_1379420_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000006001 100.0
TH2_k127_1386240_0 - - - - 0.0000000000000000000001334 101.0
TH2_k127_1386240_1 - - - - 0.000000000002945 68.0
TH2_k127_1386240_2 by glimmer - - - 0.0000000001558 63.0
TH2_k127_1386240_3 ORF located using Blastx - - - 0.0000001793 57.0
TH2_k127_1390065_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 4.187e-279 876.0
TH2_k127_1390065_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 600.0
TH2_k127_1390065_10 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 368.0
TH2_k127_1390065_11 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 360.0
TH2_k127_1390065_12 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 325.0
TH2_k127_1390065_13 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000694 273.0
TH2_k127_1390065_14 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000003682 254.0
TH2_k127_1390065_15 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000001067 240.0
TH2_k127_1390065_16 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001144 211.0
TH2_k127_1390065_17 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000004957 195.0
TH2_k127_1390065_18 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000009614 207.0
TH2_k127_1390065_19 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000001814 162.0
TH2_k127_1390065_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 482.0
TH2_k127_1390065_20 methyltransferase activity - - - 0.0000000000000000000000000000000000000000006075 164.0
TH2_k127_1390065_21 TQO small subunit DoxD K15977 - - 0.000000000000000000000000000000000000002742 151.0
TH2_k127_1390065_22 Cytochrome P460 - - - 0.000000000000000000000000000000000000003143 154.0
TH2_k127_1390065_23 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000002659 130.0
TH2_k127_1390065_24 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000000000176 115.0
TH2_k127_1390065_25 Cold shock K03704 - - 0.0000000000000000000000000004203 113.0
TH2_k127_1390065_26 - - - - 0.0000000000000000000001539 98.0
TH2_k127_1390065_27 Translation initiation factor K03113 - - 0.0000000000000000009032 90.0
TH2_k127_1390065_28 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000003633 89.0
TH2_k127_1390065_29 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000001669 55.0
TH2_k127_1390065_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 432.0
TH2_k127_1390065_31 transferase activity, transferring glycosyl groups - - - 0.0000004634 57.0
TH2_k127_1390065_33 Belongs to the universal stress protein A family - - - 0.00009995 51.0
TH2_k127_1390065_34 PFAM UspA - - - 0.000314 51.0
TH2_k127_1390065_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 421.0
TH2_k127_1390065_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 421.0
TH2_k127_1390065_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 431.0
TH2_k127_1390065_7 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 419.0
TH2_k127_1390065_8 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 386.0
TH2_k127_1390065_9 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 379.0
TH2_k127_1420448_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.106e-195 614.0
TH2_k127_1420448_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 599.0
TH2_k127_1420448_10 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 293.0
TH2_k127_1420448_11 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008842 273.0
TH2_k127_1420448_12 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000002617 233.0
TH2_k127_1420448_13 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000003051 228.0
TH2_k127_1420448_14 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000002545 175.0
TH2_k127_1420448_15 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000009191 157.0
TH2_k127_1420448_16 DUF218 domain - - - 0.0000000000000000000003688 104.0
TH2_k127_1420448_18 - - - - 0.0001146 49.0
TH2_k127_1420448_2 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 454.0
TH2_k127_1420448_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 408.0
TH2_k127_1420448_4 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 362.0
TH2_k127_1420448_5 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 339.0
TH2_k127_1420448_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 331.0
TH2_k127_1420448_7 PFAM Class II aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 326.0
TH2_k127_1420448_8 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 324.0
TH2_k127_1420448_9 belongs to the CobB CobQ family K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 313.0
TH2_k127_1425848_0 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 487.0
TH2_k127_1425848_1 COG2217 Cation transport ATPase K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000003253 253.0
TH2_k127_1425848_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000009109 93.0
TH2_k127_1485113_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.252e-243 760.0
TH2_k127_1485113_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000001724 153.0
TH2_k127_1485113_2 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000004552 147.0
TH2_k127_1485113_3 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000002454 100.0
TH2_k127_1485113_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000002865 67.0
TH2_k127_1510289_0 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 402.0
TH2_k127_1510289_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005004 272.0
TH2_k127_1567141_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 583.0
TH2_k127_1567141_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000005725 92.0
TH2_k127_1603013_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.372e-216 680.0
TH2_k127_1633461_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 9.18e-300 927.0
TH2_k127_1633461_1 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 2.209e-199 629.0
TH2_k127_1665479_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1551.0
TH2_k127_1665479_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000001982 259.0
TH2_k127_1665479_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000139 53.0
TH2_k127_1668591_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 522.0
TH2_k127_1668591_1 AsmA-like C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 319.0
TH2_k127_1738564_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.201e-307 962.0
TH2_k127_1738564_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.851e-299 938.0
TH2_k127_1738564_10 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 399.0
TH2_k127_1738564_11 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 337.0
TH2_k127_1738564_12 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 329.0
TH2_k127_1738564_13 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 326.0
TH2_k127_1738564_14 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000323 293.0
TH2_k127_1738564_15 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002373 284.0
TH2_k127_1738564_16 endonuclease III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001249 249.0
TH2_k127_1738564_17 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000001144 243.0
TH2_k127_1738564_18 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000003433 238.0
TH2_k127_1738564_19 lactate metabolic process K11473,K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000003039 239.0
TH2_k127_1738564_2 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 1.204e-236 735.0
TH2_k127_1738564_20 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000003971 165.0
TH2_k127_1738564_21 translation release factor activity - - - 0.00000000000000000000000000000000000000188 151.0
TH2_k127_1738564_22 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000354 152.0
TH2_k127_1738564_24 DivIVA protein K04074 - - 0.0000000000000000000000001914 112.0
TH2_k127_1738564_25 Regulatory protein, FmdB family - - - 0.00000000000000000004218 91.0
TH2_k127_1738564_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 9.535e-218 687.0
TH2_k127_1738564_4 chelatase, subunit ChlI K07391 - - 8.206e-211 666.0
TH2_k127_1738564_5 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 597.0
TH2_k127_1738564_6 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 604.0
TH2_k127_1738564_7 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 561.0
TH2_k127_1738564_8 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 513.0
TH2_k127_1738564_9 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 482.0
TH2_k127_1770746_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 426.0
TH2_k127_1770746_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008124 279.0
TH2_k127_1770746_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000001199 225.0
TH2_k127_1770746_3 Belongs to the bacterial glucokinase family K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.2 0.0000000000000000000000002842 107.0
TH2_k127_177323_0 Protein of unknown function (DUF3574) - - - 0.0000000000000000000000000000000000000000000000000004198 187.0
TH2_k127_1781012_0 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000149 224.0
TH2_k127_1781012_1 4Fe-4S dicluster domain - - - 0.000000000000006982 76.0
TH2_k127_1781012_2 anaerobic respiration - - - 0.000000000006186 74.0
TH2_k127_1818857_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 9.031e-214 682.0
TH2_k127_1890369_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.925e-310 959.0
TH2_k127_1890369_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 496.0
TH2_k127_1890369_2 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000009688 179.0
TH2_k127_1890369_3 Tetratricopeptide repeat - - - 0.000000000002692 75.0
TH2_k127_1906860_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1230.0
TH2_k127_1906860_1 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 329.0
TH2_k127_1906860_2 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000501 264.0
TH2_k127_1906860_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000001278 173.0
TH2_k127_1906860_4 DSBA-like thioredoxin domain - - - 0.000001045 50.0
TH2_k127_1906860_5 DSBA-like thioredoxin domain - - - 0.00003284 48.0
TH2_k127_1948600_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.779e-270 840.0
TH2_k127_1948600_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004191 289.0
TH2_k127_1948600_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000005648 259.0
TH2_k127_1964607_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.988e-194 613.0
TH2_k127_1964607_1 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000904 280.0
TH2_k127_1964607_2 ATP cone domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006586 243.0
TH2_k127_1964607_3 - - - - 0.000000000000000000000000000000000000000000000000000000000001902 218.0
TH2_k127_1964607_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000006318 62.0
TH2_k127_1964607_5 Pyridoxal-phosphate dependent enzyme K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00006219 47.0
TH2_k127_2038901_0 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000001637 164.0
TH2_k127_204450_0 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000000000000006424 184.0
TH2_k127_204450_1 Bacterial extracellular solute-binding protein - - - 0.000000000000000002977 89.0
TH2_k127_210101_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 4.515e-211 671.0
TH2_k127_210101_1 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 392.0
TH2_k127_210101_2 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 318.0
TH2_k127_210101_3 TIGRFAM iron-sulfur cluster binding protein - - - 0.00000000000000000000000000000000000000000000001935 177.0
TH2_k127_2245915_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 3.893e-300 925.0
TH2_k127_2245915_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 397.0
TH2_k127_2245915_10 regulation of RNA biosynthetic process K22109,K22301 - - 0.0000000000000000000000000000005543 130.0
TH2_k127_2245915_11 Domain of unknown function (DUF1858) - - - 0.0000000000000000003958 89.0
TH2_k127_2245915_12 Rhodanese Homology Domain - - - 0.000000000001784 69.0
TH2_k127_2245915_13 - - - - 0.000000000007092 71.0
TH2_k127_2245915_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000174 56.0
TH2_k127_2245915_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 312.0
TH2_k127_2245915_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000001094 242.0
TH2_k127_2245915_4 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000001623 222.0
TH2_k127_2245915_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000001482 226.0
TH2_k127_2245915_6 PFAM SEC-C motif K09858 - - 0.000000000000000000000000000000000000000000000000000000000323 209.0
TH2_k127_2245915_7 - - - - 0.00000000000000000000000000000000000000000000000000000006255 206.0
TH2_k127_2245915_8 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000002344 199.0
TH2_k127_2245915_9 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000007812 175.0
TH2_k127_2247460_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 550.0
TH2_k127_2247460_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 529.0
TH2_k127_2247460_2 type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 353.0
TH2_k127_2247460_3 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000006681 196.0
TH2_k127_2247460_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000001028 187.0
TH2_k127_2299714_0 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002106 258.0
TH2_k127_2303130_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016614,GO:0030151,GO:0033719,GO:0043167,GO:0043169,GO:0043546,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0097159,GO:1901363 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 314.0
TH2_k127_2303130_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003831 253.0
TH2_k127_2303130_2 GHKL domain K07709,K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000003163 177.0
TH2_k127_2303130_3 diguanylate cyclase - - - 0.000000000004646 68.0
TH2_k127_2342571_0 Protein of unknown function (DUF3604) - - - 0.0 1037.0
TH2_k127_2342571_1 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 339.0
TH2_k127_2342571_2 PPIC-type PPIASE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008958 244.0
TH2_k127_2342571_3 NADH-quinone oxidoreductase subunit F K18005 - 1.12.1.2 0.00000000000000000000000000000009932 126.0
TH2_k127_2342571_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.000000000000000006742 84.0
TH2_k127_2381599_0 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 532.0
TH2_k127_2381599_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 300.0
TH2_k127_2381599_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 293.0
TH2_k127_2381599_3 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000001776 145.0
TH2_k127_2381599_4 Cytochrome c K08906,K12263 - - 0.0000000000113 68.0
TH2_k127_2383164_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 5.362e-238 758.0
TH2_k127_2383164_1 Protein of unknown function (DUF533) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 383.0
TH2_k127_2383164_10 STAS domain - - - 0.00005465 50.0
TH2_k127_2383164_2 response regulator K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 379.0
TH2_k127_2383164_3 transmembrane transport K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 314.0
TH2_k127_2383164_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000001132 183.0
TH2_k127_2383164_5 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000359 172.0
TH2_k127_2383164_6 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000005054 151.0
TH2_k127_2383164_7 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000008119 143.0
TH2_k127_2383164_8 phosphorelay signal transduction system - - - 0.000000000000000000000000000000005782 131.0
TH2_k127_2383164_9 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000004918 100.0
TH2_k127_2391550_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007561 268.0
TH2_k127_2411430_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 411.0
TH2_k127_2420422_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 349.0
TH2_k127_2420422_1 PFAM thiamine pyrophosphate protein domain protein TPP-binding K09459 - 4.1.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000001133 269.0
TH2_k127_2420422_2 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000005016 261.0
TH2_k127_2421149_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1633.0
TH2_k127_2421149_1 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 409.0
TH2_k127_2421149_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 378.0
TH2_k127_2421149_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.0000000000000000000000001006 119.0
TH2_k127_2421149_4 transcriptional regulator - - - 0.0000000000000000002901 95.0
TH2_k127_2421149_5 Belongs to the 'phage' integrase family - - - 0.000000000248 61.0
TH2_k127_2450149_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.2e-263 829.0
TH2_k127_2450149_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 2.668e-210 667.0
TH2_k127_2450149_10 - - - - 0.000000000000000000000000006167 110.0
TH2_k127_2450149_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000004578 102.0
TH2_k127_2450149_12 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000003433 86.0
TH2_k127_2450149_13 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000005831 69.0
TH2_k127_2450149_2 DHHA2 domain K15986 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 566.0
TH2_k127_2450149_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 477.0
TH2_k127_2450149_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 447.0
TH2_k127_2450149_5 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 432.0
TH2_k127_2450149_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 351.0
TH2_k127_2450149_7 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000009237 200.0
TH2_k127_2450149_8 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000006238 132.0
TH2_k127_2450149_9 C-terminal domain of CHU protein family K21449 - - 0.00000000000000000000000000000004132 145.0
TH2_k127_2457987_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 424.0
TH2_k127_2457987_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.0000000003406 62.0
TH2_k127_2467176_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 348.0
TH2_k127_2467176_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000001063 231.0
TH2_k127_2467176_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000003277 139.0
TH2_k127_2485959_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001305 248.0
TH2_k127_2485959_1 auxin efflux carrier K07088 - - 0.0003276 44.0
TH2_k127_2494177_0 Membrane - - - 0.00000000000000000000000000000000000000000000000000004498 192.0
TH2_k127_2494177_1 - - - - 0.00000000000000000001407 92.0
TH2_k127_2494177_2 hyperosmotic response K04065 - - 0.00000000000000009618 87.0
TH2_k127_2494177_3 - - - - 0.00000000000005343 72.0
TH2_k127_2494177_4 Belongs to the UPF0337 (CsbD) family - - - 0.000000000004838 70.0
TH2_k127_2494177_5 Protein of unknown function (DUF3309) - - - 0.0000000001056 62.0
TH2_k127_2506209_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 614.0
TH2_k127_2506209_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 295.0
TH2_k127_2506209_2 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000001285 243.0
TH2_k127_2515822_1 hyperosmotic response K04065 - - 0.0000000000000000002776 91.0
TH2_k127_2529643_0 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 406.0
TH2_k127_2552772_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 549.0
TH2_k127_2552772_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 364.0
TH2_k127_2552772_3 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000002646 102.0
TH2_k127_2552772_4 electron transfer activity K03439,K05337 - 2.1.1.33 0.0000000000005062 70.0
TH2_k127_2552772_5 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000002853 67.0
TH2_k127_2561219_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 370.0
TH2_k127_2561219_1 Flavodoxin-like protein K11748 - - 0.000000000661 61.0
TH2_k127_2571914_0 FtsX-like permease family K02004 - - 2.988e-313 977.0
TH2_k127_2571914_1 Nitroreductase - - - 1.399e-212 676.0
TH2_k127_2571914_10 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000001916 264.0
TH2_k127_2571914_11 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001071 257.0
TH2_k127_2571914_12 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000002009 176.0
TH2_k127_2571914_13 PFAM Smr protein MutS2 - - - 0.00000000000000000000000001292 117.0
TH2_k127_2571914_14 - - - - 0.000000000000000000004121 98.0
TH2_k127_2571914_15 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000099 99.0
TH2_k127_2571914_17 - - - - 0.00000000002257 67.0
TH2_k127_2571914_18 Carboxymuconolactone decarboxylase family - - - 0.0000000006271 65.0
TH2_k127_2571914_2 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 566.0
TH2_k127_2571914_3 Alanine-glyoxylate amino-transferase K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 508.0
TH2_k127_2571914_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 504.0
TH2_k127_2571914_5 CAAX prenyl protease N-terminal, five membrane helices - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 487.0
TH2_k127_2571914_6 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 435.0
TH2_k127_2571914_7 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 370.0
TH2_k127_2571914_8 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 316.0
TH2_k127_2571914_9 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 308.0
TH2_k127_2574414_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1108.0
TH2_k127_2574414_1 4Fe-4S binding domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003253 258.0
TH2_k127_2574414_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000003889 211.0
TH2_k127_2574414_3 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000002237 205.0
TH2_k127_2574414_4 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000000001264 139.0
TH2_k127_2574414_5 Protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000005348 137.0
TH2_k127_2574414_6 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000000001884 115.0
TH2_k127_2574414_7 part of a sulfur-relay system K11179 - - 0.000000000000000000000000004066 113.0
TH2_k127_2574414_8 electron transfer activity K05337,K17247 - - 0.00000000000000000000015 98.0
TH2_k127_261026_0 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 456.0
TH2_k127_2623778_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1100.0
TH2_k127_2623778_1 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 491.0
TH2_k127_2623778_10 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000001334 172.0
TH2_k127_2623778_11 response regulator - - - 0.0000000000000000000000000000000000000003082 162.0
TH2_k127_2623778_12 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000001318 151.0
TH2_k127_2623778_13 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000001024 127.0
TH2_k127_2623778_14 Protein of unknown function (DUF2845) - - - 0.00000000000000000114 89.0
TH2_k127_2623778_16 TIGRFAM regulatory protein, FmdB - - - 0.000005772 51.0
TH2_k127_2623778_17 cheY-homologous receiver domain K02658 - - 0.00001538 57.0
TH2_k127_2623778_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 361.0
TH2_k127_2623778_3 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 357.0
TH2_k127_2623778_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 323.0
TH2_k127_2623778_5 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 317.0
TH2_k127_2623778_6 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 286.0
TH2_k127_2623778_7 PFAM ABC transporter related K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006778 274.0
TH2_k127_2623778_8 Belongs to the Fur family K02076,K03711 GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000001563 189.0
TH2_k127_2623778_9 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000006741 194.0
TH2_k127_2669211_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 2.8e-228 717.0
TH2_k127_2669211_1 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 546.0
TH2_k127_2669211_10 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000901 190.0
TH2_k127_2669211_11 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000001238 145.0
TH2_k127_2669211_12 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.00000000000000000001675 99.0
TH2_k127_2669211_13 Tetratricopeptide repeat-like domain - - - 0.0000000000000004936 87.0
TH2_k127_2669211_14 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000004777 63.0
TH2_k127_2669211_15 ATPase (AAA superfamily K07133 - - 0.000000002195 64.0
TH2_k127_2669211_16 - - - - 0.0000003795 54.0
TH2_k127_2669211_18 PilZ domain - - - 0.000001373 57.0
TH2_k127_2669211_19 - - - - 0.000176 44.0
TH2_k127_2669211_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 562.0
TH2_k127_2669211_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 539.0
TH2_k127_2669211_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 537.0
TH2_k127_2669211_5 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 332.0
TH2_k127_2669211_6 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 321.0
TH2_k127_2669211_7 zinc ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005457 259.0
TH2_k127_2669211_8 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000201 212.0
TH2_k127_2669211_9 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000000000000000000003682 196.0
TH2_k127_2689686_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 310.0
TH2_k127_2689686_1 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000000006287 243.0
TH2_k127_2689686_2 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000001739 198.0
TH2_k127_2689686_3 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000002013 185.0
TH2_k127_2689686_4 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000004579 76.0
TH2_k127_2699154_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 1.16e-245 767.0
TH2_k127_2722528_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1388.0
TH2_k127_2722528_1 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 319.0
TH2_k127_2722528_2 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0008002 42.0
TH2_k127_2722558_0 family UPF0324 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 551.0
TH2_k127_2722558_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 548.0
TH2_k127_2722558_10 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004544 277.0
TH2_k127_2722558_11 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 259.0
TH2_k127_2722558_12 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000001576 252.0
TH2_k127_2722558_13 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000314 164.0
TH2_k127_2722558_14 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000673 171.0
TH2_k127_2722558_15 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000000000000004022 172.0
TH2_k127_2722558_16 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000000000002069 147.0
TH2_k127_2722558_17 PFAM CheW-like domain K03408 - - 0.00000000000000000000000000000001826 131.0
TH2_k127_2722558_18 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000028 127.0
TH2_k127_2722558_19 methylamine metabolic process - - - 0.000000000000000000001167 102.0
TH2_k127_2722558_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 527.0
TH2_k127_2722558_20 Two component signalling adaptor domain K03408 - - 0.00000000000000000008156 98.0
TH2_k127_2722558_21 - - - - 0.00000000001582 67.0
TH2_k127_2722558_22 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000003799 61.0
TH2_k127_2722558_23 PFAM Rhodanese domain protein - - - 0.0005712 47.0
TH2_k127_2722558_3 Cytochrome c bacterial - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 492.0
TH2_k127_2722558_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 358.0
TH2_k127_2722558_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 320.0
TH2_k127_2722558_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 302.0
TH2_k127_2722558_7 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008361 294.0
TH2_k127_2722558_8 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 291.0
TH2_k127_2722558_9 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007057 308.0
TH2_k127_2743725_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 1.593e-295 929.0
TH2_k127_2743725_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 4.456e-196 622.0
TH2_k127_2743725_2 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 312.0
TH2_k127_2743725_3 thiosulfate sulfurtransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001563 255.0
TH2_k127_2743725_4 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000006835 167.0
TH2_k127_2743725_5 Sensor histidine kinase, Cache_1, HAMP and PAS domain-containing - - - 0.00000000000000000000000000000000000009091 157.0
TH2_k127_2743725_6 Catalyzes the synthesis of activated sulfate K00860,K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000014 143.0
TH2_k127_2743725_7 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000418 115.0
TH2_k127_2743725_8 Histidine kinase - - - 0.0000000000000000000002046 110.0
TH2_k127_2743725_9 deoxyhypusine monooxygenase activity - - - 0.000001078 59.0
TH2_k127_2756470_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 6.794e-202 634.0
TH2_k127_2756470_1 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 554.0
TH2_k127_2756470_2 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 361.0
TH2_k127_2756470_3 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006942 257.0
TH2_k127_2756470_4 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000007604 244.0
TH2_k127_2756470_5 acetyltransferase - - - 0.000000000000000000000000000000000000005524 149.0
TH2_k127_2756470_6 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.000000000000000000000000000000002285 142.0
TH2_k127_2756470_7 cheY-homologous receiver domain - - - 0.00000000000000009476 84.0
TH2_k127_2758588_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 1.167e-199 638.0
TH2_k127_2785135_0 PFAM ferredoxin-dependent glutamate synthase - - - 2.721e-295 912.0
TH2_k127_2785135_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.145e-257 804.0
TH2_k127_2785135_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 573.0
TH2_k127_2785135_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 441.0
TH2_k127_2785135_4 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 406.0
TH2_k127_2785135_5 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 386.0
TH2_k127_2785135_6 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008246 264.0
TH2_k127_2785135_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000004105 217.0
TH2_k127_2785135_8 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000001455 176.0
TH2_k127_2785135_9 thiamine diphosphate biosynthetic process K03154 - - 0.0000000000001472 72.0
TH2_k127_2815455_0 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 406.0
TH2_k127_2845022_0 transposition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 445.0
TH2_k127_2845022_1 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.000000000000000002443 87.0
TH2_k127_2882111_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000006604 136.0
TH2_k127_2882111_1 Histidine kinase - - - 0.000000000000000000000000000000001341 136.0
TH2_k127_288908_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000003129 265.0
TH2_k127_288908_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000001277 211.0
TH2_k127_288908_2 COGs COG4446 conserved - - - 0.000000000000000000000000000000000000000002583 159.0
TH2_k127_288908_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000144 126.0
TH2_k127_288908_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000005797 121.0
TH2_k127_288908_5 PFAM PQ loop repeat K15383 - - 0.0000000000000000000000001343 110.0
TH2_k127_2907398_0 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 549.0
TH2_k127_2907398_1 Bacterial periplasmic substrate-binding proteins K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 299.0
TH2_k127_291206_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 320.0
TH2_k127_291206_1 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000006275 104.0
TH2_k127_291206_3 Transposase - - - 0.000002895 52.0
TH2_k127_2925076_0 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004798 263.0
TH2_k127_2925076_1 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000001706 196.0
TH2_k127_2925076_2 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.00000000000000000000000000000000003556 139.0
TH2_k127_2925076_3 Glutathione peroxidase - - - 0.00000000000000000000000000000000008925 139.0
TH2_k127_2925076_4 - - - - 0.0000000000000000000000000007807 118.0
TH2_k127_2925076_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000001814 62.0
TH2_k127_293547_0 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 335.0
TH2_k127_293547_1 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.00000000000000000007224 93.0
TH2_k127_293547_2 Belongs to the UPF0434 family K09791 - - 0.0000000000000000001261 89.0
TH2_k127_293829_0 sequence-specific DNA binding K18830 - - 0.0000000000000000000000000000000000000000002991 161.0
TH2_k127_293829_1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000001546 116.0
TH2_k127_293829_2 Protein conserved in bacteria - - - 0.00000000000000000000000005109 110.0
TH2_k127_293829_3 response regulator K07712 - - 0.0000000000000006585 82.0
TH2_k127_2984855_0 Member of the two-component regulatory system AtoS AtoC. In the presence of acetoacetate, AtoS AtoC stimulates the expression of the atoDAEB operon, leading to short chain fatty acid catabolism and activation of the poly-(R)-3-hydroxybutyrate (cPHB) biosynthetic pathway. Also induces the operon in response to spermidine. Involved in the regulation of motility and chemotaxis, via transcriptional induction of the flagellar regulon. AtoS is a membrane-associated kinase that phosphorylates and activates AtoC in response to environmental signals K07710 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000006044 200.0
TH2_k127_2984855_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000001444 77.0
TH2_k127_2991512_0 rRNA binding K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 364.0
TH2_k127_2991512_1 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001514 106.0
TH2_k127_2998887_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 7.588e-214 670.0
TH2_k127_2998887_1 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 524.0
TH2_k127_2998887_10 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000001112 151.0
TH2_k127_2998887_11 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000018 125.0
TH2_k127_2998887_12 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000001231 95.0
TH2_k127_2998887_13 DnaJ molecular chaperone homology domain - - - 0.000000001069 71.0
TH2_k127_2998887_14 TonB family K03646,K03832 - - 0.00000361 53.0
TH2_k127_2998887_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 411.0
TH2_k127_2998887_3 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 403.0
TH2_k127_2998887_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 350.0
TH2_k127_2998887_5 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 344.0
TH2_k127_2998887_6 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005464 291.0
TH2_k127_2998887_7 ferrous iron binding K06990,K09141 - - 0.0000000000000000000000000000000000000000000000000000000001631 208.0
TH2_k127_2998887_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000005392 198.0
TH2_k127_2998887_9 heat shock protein binding - - - 0.0000000000000000000000000000000000000827 153.0
TH2_k127_3010590_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 467.0
TH2_k127_3010590_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 299.0
TH2_k127_3010590_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002058 250.0
TH2_k127_3010590_3 ACT domain - - - 0.000000000000000000000000000000000000000000000000000000009631 201.0
TH2_k127_30312_0 Transglycosylase K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000007237 273.0
TH2_k127_3240817_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1651.0
TH2_k127_3240817_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 9.375e-285 884.0
TH2_k127_3240817_10 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001935 263.0
TH2_k127_3240817_11 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000001555 254.0
TH2_k127_3240817_12 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008789 243.0
TH2_k127_3240817_13 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000001059 236.0
TH2_k127_3240817_14 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000469 233.0
TH2_k127_3240817_15 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000002423 217.0
TH2_k127_3240817_16 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000002902 223.0
TH2_k127_3240817_17 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000002165 211.0
TH2_k127_3240817_18 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000001175 147.0
TH2_k127_3240817_19 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000001327 137.0
TH2_k127_3240817_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 4.061e-201 634.0
TH2_k127_3240817_20 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000002555 124.0
TH2_k127_3240817_21 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000004068 120.0
TH2_k127_3240817_22 - - - - 0.0000000000000000000000000006644 118.0
TH2_k127_3240817_23 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000004584 106.0
TH2_k127_3240817_24 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.0000000000000000000001574 100.0
TH2_k127_3240817_25 Belongs to the sulfur carrier protein TusA family - - - 0.0000001693 59.0
TH2_k127_3240817_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 606.0
TH2_k127_3240817_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 546.0
TH2_k127_3240817_5 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 494.0
TH2_k127_3240817_6 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 477.0
TH2_k127_3240817_7 PFAM PfkB K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 380.0
TH2_k127_3240817_8 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 314.0
TH2_k127_3240817_9 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000002578 270.0
TH2_k127_3259727_0 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 347.0
TH2_k127_3259727_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000003963 181.0
TH2_k127_3259727_2 MGS-like domain - - - 0.00000000000000000000000000000000000000000000005098 178.0
TH2_k127_3259727_3 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000000000000000001104 149.0
TH2_k127_3259727_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000008237 154.0
TH2_k127_3259727_5 - - - - 0.0000000000000003222 86.0
TH2_k127_32999_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 621.0
TH2_k127_32999_1 Domain of unknown function (DUF362) K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 414.0
TH2_k127_32999_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 358.0
TH2_k127_32999_3 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000001711 203.0
TH2_k127_32999_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000000000004447 158.0
TH2_k127_32999_5 - - - - 0.00000000000000001279 87.0
TH2_k127_32999_7 VanZ like family - - - 0.00000005806 58.0
TH2_k127_330955_0 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006402 236.0
TH2_k127_330955_1 Streptomycin adenylyltransferase K05593 - - 0.000000000000000000000000000000000000000173 153.0
TH2_k127_330955_2 Putative transposase - - - 0.00000000000000002817 86.0
TH2_k127_3354480_0 FAD binding domain K00394 - 1.8.99.2 0.0 1024.0
TH2_k127_3354480_1 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 3.57e-227 707.0
TH2_k127_3354480_10 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000002264 258.0
TH2_k127_3354480_11 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000003106 248.0
TH2_k127_3354480_12 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000001854 211.0
TH2_k127_3354480_13 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000004813 188.0
TH2_k127_3354480_14 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000001416 138.0
TH2_k127_3354480_15 RDD family - - - 0.000000000000000000000000006638 114.0
TH2_k127_3354480_16 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000000000001099 108.0
TH2_k127_3354480_17 - - - - 0.000000000000000000000001654 105.0
TH2_k127_3354480_18 - - - - 0.0000000000007571 71.0
TH2_k127_3354480_2 Histidine kinase - - - 2.081e-199 662.0
TH2_k127_3354480_3 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 528.0
TH2_k127_3354480_4 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 487.0
TH2_k127_3354480_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 420.0
TH2_k127_3354480_6 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 346.0
TH2_k127_3354480_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 338.0
TH2_k127_3354480_8 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 307.0
TH2_k127_3354480_9 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008672 263.0
TH2_k127_3357582_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2093.0
TH2_k127_3357582_1 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1618.0
TH2_k127_3357582_10 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 290.0
TH2_k127_3357582_11 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003618 264.0
TH2_k127_3357582_12 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003893 255.0
TH2_k127_3357582_13 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000001592 217.0
TH2_k127_3357582_14 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000001152 206.0
TH2_k127_3357582_15 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000482 219.0
TH2_k127_3357582_16 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000001291 194.0
TH2_k127_3357582_17 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000228 185.0
TH2_k127_3357582_18 heme-binding sites - - - 0.000000000000000000000000000000000000000148 159.0
TH2_k127_3357582_19 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000002932 148.0
TH2_k127_3357582_2 Surface antigen K07277 - - 7.369e-249 788.0
TH2_k127_3357582_20 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000001641 142.0
TH2_k127_3357582_21 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000007476 129.0
TH2_k127_3357582_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.000000000000000000000000000007738 125.0
TH2_k127_3357582_23 GDP-mannose mannosyl hydrolase activity - - - 0.00000000000000002949 83.0
TH2_k127_3357582_24 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000008361 74.0
TH2_k127_3357582_25 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000003016 71.0
TH2_k127_3357582_26 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000003767 68.0
TH2_k127_3357582_3 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 603.0
TH2_k127_3357582_4 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 557.0
TH2_k127_3357582_5 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 546.0
TH2_k127_3357582_6 phosphorelay signal transduction system K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 440.0
TH2_k127_3357582_7 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 383.0
TH2_k127_3357582_8 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 365.0
TH2_k127_3357582_9 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 336.0
TH2_k127_3359696_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1701.0
TH2_k127_3359696_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 304.0
TH2_k127_3359696_2 PFAM outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000231 171.0
TH2_k127_3359696_3 Transposase - - - 0.000000000000000000000000000000000000001481 151.0
TH2_k127_336940_0 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000000000000000000000000101 219.0
TH2_k127_336940_1 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000001361 222.0
TH2_k127_33832_0 PFAM Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 409.0
TH2_k127_33832_1 SWI complex, BAF60b domains - - - 0.00000000000000000000000000000002042 128.0
TH2_k127_33832_2 Membrane transport protein K07088 - - 0.000002466 57.0
TH2_k127_3389051_0 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 495.0
TH2_k127_3389051_1 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 484.0
TH2_k127_3389051_10 DsrE/DsrF-like family K07092 - - 0.00004545 51.0
TH2_k127_3389051_2 ATP synthase subunit J K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 410.0
TH2_k127_3389051_3 PFAM TrkA-N domain protein K03499 - - 0.00000000000000000000000000000000000000000000000000000000001447 214.0
TH2_k127_3389051_4 4Fe-4S double cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000001076 201.0
TH2_k127_3389051_5 - - - - 0.000000000000000000000000000000000000000000000002022 184.0
TH2_k127_3389051_6 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000001871 156.0
TH2_k127_3389051_7 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000012 125.0
TH2_k127_3389051_8 TfoX N-terminal domain - - - 0.000000000000000000000003424 105.0
TH2_k127_3389051_9 monooxygenase activity - - - 0.00000001712 57.0
TH2_k127_3394466_0 ABC1 family - - - 0.00000000000000000000000000000007239 135.0
TH2_k127_3394655_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 581.0
TH2_k127_3426657_0 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 299.0
TH2_k127_3426657_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002064 266.0
TH2_k127_3426657_2 MarR family transcriptional K15973 - - 0.00000000000000000000000000000000000006075 145.0
TH2_k127_3485087_0 - - - - 0.000000000000000000000000000000000000000000000000000000004742 209.0
TH2_k127_3485087_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000001422 186.0
TH2_k127_3524619_0 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000892 566.0
TH2_k127_3524619_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 423.0
TH2_k127_3524619_2 nucleotide metabolic process - - - 0.0000000000000000000000000000000000001931 150.0
TH2_k127_3524619_3 - - - - 0.000005826 57.0
TH2_k127_3529461_0 PFAM MotA TolQ ExbB proton channel K02556 - - 0.00000000000000000000000000000000002075 143.0
TH2_k127_3529461_1 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.00004279 51.0
TH2_k127_3538430_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 5.687e-223 705.0
TH2_k127_3538430_1 Aminotransferase class-III K01845 - 5.4.3.8 1.052e-200 632.0
TH2_k127_3538430_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000001399 210.0
TH2_k127_357220_0 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 423.0
TH2_k127_357220_1 AMP binding - - - 0.0000000001311 63.0
TH2_k127_3574659_0 PFAM Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 364.0
TH2_k127_3574659_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000004447 230.0
TH2_k127_3574659_2 Beta-eliminating lyase K04487 - 2.8.1.7 0.000000000000000001626 85.0
TH2_k127_3609049_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 3.232e-257 803.0
TH2_k127_3609049_1 Nickel-dependent hydrogenase K00436 - 1.12.1.2 4.275e-244 760.0
TH2_k127_3609049_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001673 244.0
TH2_k127_3609049_3 hydrogenase maturation protease - - - 0.00000000000000000000000000000000003095 141.0
TH2_k127_3612250_0 PFAM transposase IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005646 510.0
TH2_k127_3612250_1 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 425.0
TH2_k127_3630841_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1498.0
TH2_k127_3630841_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 469.0
TH2_k127_3630841_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 298.0
TH2_k127_3630841_3 PFAM PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007653 246.0
TH2_k127_3630841_4 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000003889 218.0
TH2_k127_3630841_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000003347 194.0
TH2_k127_3633239_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 429.0
TH2_k127_3633239_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 335.0
TH2_k127_3658442_0 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 400.0
TH2_k127_3658442_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000005649 119.0
TH2_k127_3699547_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 556.0
TH2_k127_3699547_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 419.0
TH2_k127_3699547_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 344.0
TH2_k127_3699547_3 Oligopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001144 274.0
TH2_k127_3699547_4 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003802 237.0
TH2_k127_3699547_5 PFAM Protein phosphatase K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000009276 221.0
TH2_k127_3699547_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000003654 198.0
TH2_k127_3699547_7 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000002056 93.0
TH2_k127_3699547_8 - - - - 0.00000000001249 68.0
TH2_k127_3699547_9 Ferritin-like domain K03594 - 1.16.3.1 0.000002679 51.0
TH2_k127_3735383_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.65e-304 937.0
TH2_k127_3764184_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1148.0
TH2_k127_3764184_1 flavodoxin nitric oxide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 477.0
TH2_k127_3764184_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 330.0
TH2_k127_3764184_3 - - - - 0.00000000000000000000000000000000000000000000002872 174.0
TH2_k127_3764184_4 Hpt domain - - - 0.0000000000000000000000000000000000002047 154.0
TH2_k127_3764184_5 response regulator, receiver K03413 - - 0.00000000000000000007672 94.0
TH2_k127_3764184_6 Cysteine-rich small domain K07162 - - 0.000000000000000004033 86.0
TH2_k127_3764184_7 - - - - 0.0000000007007 67.0
TH2_k127_377055_0 DNA photolyase K01669 - 4.1.99.3 3.998e-195 618.0
TH2_k127_377055_1 YHS domain protein - - - 0.00000000000000000000000000000000000000000000000000000001155 201.0
TH2_k127_377055_2 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000001241 186.0
TH2_k127_377055_3 - - - - 0.000000000000000000000008344 106.0
TH2_k127_3774051_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 330.0
TH2_k127_3804244_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000003575 212.0
TH2_k127_3804244_1 Adenylate cyclase - - - 0.0000000000000000001598 97.0
TH2_k127_3804244_2 Transposase - - - 0.000000000001511 75.0
TH2_k127_3804244_3 Transposase K07494 - - 0.000000000001988 74.0
TH2_k127_3826141_0 - - - - 0.0000000000000000000000000003484 114.0
TH2_k127_3826141_1 - - - - 0.000000000000000000004511 94.0
TH2_k127_3826141_2 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 0.0000000000000000002959 88.0
TH2_k127_3826141_3 - - - - 0.000000000000005211 80.0
TH2_k127_3863629_0 electron transfer activity - - - 0.000002722 53.0
TH2_k127_3865761_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.424e-285 898.0
TH2_k127_3865761_1 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 3.327e-268 852.0
TH2_k127_3865761_10 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 384.0
TH2_k127_3865761_11 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 339.0
TH2_k127_3865761_12 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 331.0
TH2_k127_3865761_13 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 329.0
TH2_k127_3865761_14 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 320.0
TH2_k127_3865761_15 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 304.0
TH2_k127_3865761_16 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001354 288.0
TH2_k127_3865761_17 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001613 281.0
TH2_k127_3865761_18 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000174 282.0
TH2_k127_3865761_19 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000006606 256.0
TH2_k127_3865761_2 DNA polymerase A domain K02335 - 2.7.7.7 5.739e-261 831.0
TH2_k127_3865761_20 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000001315 234.0
TH2_k127_3865761_21 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000002819 229.0
TH2_k127_3865761_22 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000006464 230.0
TH2_k127_3865761_23 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000000000344 206.0
TH2_k127_3865761_24 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000069 193.0
TH2_k127_3865761_25 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000004069 163.0
TH2_k127_3865761_26 MarC family integral membrane protein - - - 0.000000000000000000000000000000000000000002809 162.0
TH2_k127_3865761_27 Sh3 type 3 domain protein K02450,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000002564 156.0
TH2_k127_3865761_28 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000499 129.0
TH2_k127_3865761_29 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000002146 121.0
TH2_k127_3865761_3 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 1.203e-256 811.0
TH2_k127_3865761_30 metalloendopeptidase activity K03799 - - 0.00000000000000000000005558 111.0
TH2_k127_3865761_31 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000001025 91.0
TH2_k127_3865761_32 positive regulation of growth - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000000000000008923 83.0
TH2_k127_3865761_33 assembly protein PilO K02664 - - 0.00000000000000006011 88.0
TH2_k127_3865761_34 Domain of unknown function (DUF4912) K09942 - - 0.0000000000001676 83.0
TH2_k127_3865761_35 Pilus assembly protein, PilP K02665 - - 0.00000000001078 72.0
TH2_k127_3865761_36 Protein of unknown function (DUF721) - - - 0.00000003676 63.0
TH2_k127_3865761_37 Fimbrial assembly protein (PilN) K02663 - - 0.0000000797 61.0
TH2_k127_3865761_38 PFAM SEC-C motif K09858 - - 0.000001758 59.0
TH2_k127_3865761_39 PFAM phosphate transporter K03306 - - 0.00001436 49.0
TH2_k127_3865761_4 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 2.163e-196 631.0
TH2_k127_3865761_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 589.0
TH2_k127_3865761_6 - K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 509.0
TH2_k127_3865761_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 466.0
TH2_k127_3865761_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 460.0
TH2_k127_3865761_9 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 417.0
TH2_k127_3865780_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1006.0
TH2_k127_3865780_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 2.627e-292 906.0
TH2_k127_3865780_10 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 415.0
TH2_k127_3865780_11 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 406.0
TH2_k127_3865780_12 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 329.0
TH2_k127_3865780_13 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002159 258.0
TH2_k127_3865780_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000002694 255.0
TH2_k127_3865780_15 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000001877 225.0
TH2_k127_3865780_16 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000003411 215.0
TH2_k127_3865780_17 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000144 203.0
TH2_k127_3865780_18 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000007124 172.0
TH2_k127_3865780_19 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000152 173.0
TH2_k127_3865780_2 Dehydratase family K01687 - 4.2.1.9 2.127e-262 817.0
TH2_k127_3865780_20 peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000001709 136.0
TH2_k127_3865780_21 Protein of unknown function (DUF465) K09794 - - 0.00000000000000002227 83.0
TH2_k127_3865780_22 Evidence 4 Homologs of previously reported genes of - - - 0.000000000005273 68.0
TH2_k127_3865780_3 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 595.0
TH2_k127_3865780_4 GTP-binding GTPase Middle Region K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 603.0
TH2_k127_3865780_5 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 574.0
TH2_k127_3865780_6 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 473.0
TH2_k127_3865780_7 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 473.0
TH2_k127_3865780_8 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 464.0
TH2_k127_3865780_9 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 452.0
TH2_k127_3871473_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000001265 196.0
TH2_k127_3871473_1 DegT/DnrJ/EryC1/StrS aminotransferase family K14260 - 2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000001676 182.0
TH2_k127_3895131_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.152e-270 841.0
TH2_k127_3895131_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 467.0
TH2_k127_3895131_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 318.0
TH2_k127_3895131_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 292.0
TH2_k127_3895131_4 (Rhomboid) family K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009176 248.0
TH2_k127_3895131_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000004174 193.0
TH2_k127_3895131_6 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000002972 190.0
TH2_k127_3895131_7 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000009077 176.0
TH2_k127_3895131_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000001017 143.0
TH2_k127_3895131_9 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000001767 143.0
TH2_k127_3908322_0 PFAM major facilitator superfamily MFS_1 K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000009567 245.0
TH2_k127_3908322_1 - - - - 0.000000000000000000000000000000000000000000000000001415 188.0
TH2_k127_3908322_2 PFAM Fe-S cluster domain protein - - - 0.0000000000000000000000000000000000000001207 160.0
TH2_k127_3908322_3 Protein of unknown function (DUF1189) - - - 0.000000000000000002631 94.0
TH2_k127_3908322_4 - - - - 0.00000000000000002702 84.0
TH2_k127_3908322_5 Ribosomal RNA adenine dimethylase - - - 0.000000000001982 75.0
TH2_k127_3908322_6 EAL domain protein - - - 0.00003359 51.0
TH2_k127_390995_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 1.173e-201 643.0
TH2_k127_390995_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 533.0
TH2_k127_390995_10 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 328.0
TH2_k127_390995_11 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 312.0
TH2_k127_390995_12 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000743 248.0
TH2_k127_390995_13 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000189 229.0
TH2_k127_390995_14 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000003505 185.0
TH2_k127_390995_15 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000004585 133.0
TH2_k127_390995_16 epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000007451 119.0
TH2_k127_390995_17 Essential cell division protein K03589 - - 0.0000000000001541 81.0
TH2_k127_390995_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 517.0
TH2_k127_390995_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 468.0
TH2_k127_390995_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 419.0
TH2_k127_390995_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 403.0
TH2_k127_390995_6 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 381.0
TH2_k127_390995_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 372.0
TH2_k127_390995_8 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 353.0
TH2_k127_390995_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 340.0
TH2_k127_3913508_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 454.0
TH2_k127_3913508_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 311.0
TH2_k127_3913508_2 - - - - 0.000000000000000000000000000000000000000000000000000001133 203.0
TH2_k127_3913508_3 - - - - 0.00000000000000000000000004546 117.0
TH2_k127_3913508_4 Prenyltransferase K13277 - - 0.00000000000192 78.0
TH2_k127_3913508_5 regulatory protein, FmdB family - - - 0.000000000004151 68.0
TH2_k127_3913508_7 Regulatory protein, FmdB family - - - 0.00014 49.0
TH2_k127_3913508_8 - - - - 0.0006664 49.0
TH2_k127_3913508_9 - - - - 0.0008318 51.0
TH2_k127_3985485_0 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 521.0
TH2_k127_3985485_1 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 514.0
TH2_k127_3985485_10 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000002017 190.0
TH2_k127_3985485_11 GatB Yqey domain protein K09117 - - 0.000000000000000000000000000000000000003983 150.0
TH2_k127_3985485_12 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000002508 153.0
TH2_k127_3985485_13 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000006508 130.0
TH2_k127_3985485_14 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001932 92.0
TH2_k127_3985485_2 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 449.0
TH2_k127_3985485_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 415.0
TH2_k127_3985485_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 406.0
TH2_k127_3985485_5 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 383.0
TH2_k127_3985485_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 286.0
TH2_k127_3985485_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000004135 242.0
TH2_k127_3985485_8 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000565 233.0
TH2_k127_3985485_9 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000005748 194.0
TH2_k127_4004846_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 396.0
TH2_k127_4004846_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 347.0
TH2_k127_4004846_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000001834 232.0
TH2_k127_4004846_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000002669 97.0
TH2_k127_4023603_0 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 446.0
TH2_k127_4023603_1 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000000000001716 177.0
TH2_k127_4023603_2 Fibronectin type 3 domain K20276 - - 0.0000000000000000000002743 114.0
TH2_k127_4045362_0 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 517.0
TH2_k127_4045362_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 407.0
TH2_k127_4045362_2 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009925 405.0
TH2_k127_4045362_3 Transposase (IS116 IS110 IS902 family) K07486 - - 0.000000000000000000000000000000000000000000000000000000006157 202.0
TH2_k127_4045362_4 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000000000000000003405 171.0
TH2_k127_4045362_5 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000000000003375 114.0
TH2_k127_4045362_6 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.00000000000000000000000003649 109.0
TH2_k127_4045362_7 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000105 108.0
TH2_k127_4054486_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 571.0
TH2_k127_4054486_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 396.0
TH2_k127_4054486_2 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 330.0
TH2_k127_4054486_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 320.0
TH2_k127_4054486_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002175 275.0
TH2_k127_4054486_5 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000002544 158.0
TH2_k127_4054486_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000004303 81.0
TH2_k127_4055763_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.603e-281 879.0
TH2_k127_4055763_1 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 7.609e-220 696.0
TH2_k127_4055763_10 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 396.0
TH2_k127_4055763_11 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 345.0
TH2_k127_4055763_12 metal-dependent phosphohydrolase HD sub K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 338.0
TH2_k127_4055763_13 cellulose synthase operon protein YhjU - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004209 283.0
TH2_k127_4055763_14 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006559 244.0
TH2_k127_4055763_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000009376 227.0
TH2_k127_4055763_16 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000001066 181.0
TH2_k127_4055763_17 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000372 146.0
TH2_k127_4055763_18 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.00000000000000000000000000001964 118.0
TH2_k127_4055763_19 SMART Cold shock protein K03704 - - 0.000000000000000000000000003035 112.0
TH2_k127_4055763_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 606.0
TH2_k127_4055763_21 N-Acetylmuramoyl-L-alanine amidase - - - 0.000000001683 65.0
TH2_k127_4055763_23 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0008167 52.0
TH2_k127_4055763_3 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 556.0
TH2_k127_4055763_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 550.0
TH2_k127_4055763_5 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 546.0
TH2_k127_4055763_6 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 482.0
TH2_k127_4055763_7 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 454.0
TH2_k127_4055763_8 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 439.0
TH2_k127_4055763_9 Cellulose synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 422.0
TH2_k127_4056592_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 552.0
TH2_k127_4056592_1 Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007576 420.0
TH2_k127_4056592_2 Pfam Transposase K07483 - - 0.00000000000000000000000000000000000226 141.0
TH2_k127_4058172_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.14e-223 699.0
TH2_k127_4066294_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 483.0
TH2_k127_4066294_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 407.0
TH2_k127_4066294_2 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 339.0
TH2_k127_4066294_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000005119 115.0
TH2_k127_4066294_4 - - - - 0.00000000000000002581 84.0
TH2_k127_4175664_0 Belongs to the GPI family K01810 - 5.3.1.9 1.732e-206 646.0
TH2_k127_4195397_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 5.261e-200 635.0
TH2_k127_4195397_1 Lysin motif - - - 0.00000000000000000000000000002545 129.0
TH2_k127_4195397_2 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000001199 115.0
TH2_k127_4213050_0 - - - - 3.988e-282 877.0
TH2_k127_4405976_0 4Fe-4S dicluster domain - - - 1.824e-305 942.0
TH2_k127_4405976_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 501.0
TH2_k127_4405976_2 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 423.0
TH2_k127_4405976_3 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 335.0
TH2_k127_4405976_4 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.000000000000000000000000000000000000000000000000003494 185.0
TH2_k127_4405976_5 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.0000000000000000000000000000000000000000000000003848 183.0
TH2_k127_4405976_6 - - - - 0.0000000000000000000000000000000000000000000000005686 177.0
TH2_k127_4405976_7 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000002236 119.0
TH2_k127_4405976_8 lyase activity - - - 0.0000000000000002345 83.0
TH2_k127_4405976_9 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000009133 72.0
TH2_k127_440690_0 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001793 287.0
TH2_k127_440690_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000115 166.0
TH2_k127_446815_0 ATP-grasp domain K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 614.0
TH2_k127_446815_1 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000001038 164.0
TH2_k127_446815_2 membrane K09790 - - 0.000000000000000000002944 97.0
TH2_k127_4507358_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.668e-316 991.0
TH2_k127_4507358_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 9.53e-280 872.0
TH2_k127_4507358_10 HlyD membrane-fusion protein of T1SS K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 389.0
TH2_k127_4507358_11 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 390.0
TH2_k127_4507358_12 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 318.0
TH2_k127_4507358_13 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001205 278.0
TH2_k127_4507358_14 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000005621 218.0
TH2_k127_4507358_15 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000009652 214.0
TH2_k127_4507358_16 Curli production assembly/transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000001506 214.0
TH2_k127_4507358_17 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000000001914 207.0
TH2_k127_4507358_18 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000002183 211.0
TH2_k127_4507358_19 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000001057 189.0
TH2_k127_4507358_2 Sugar (and other) transporter K03446 - - 2.654e-231 726.0
TH2_k127_4507358_20 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000002586 138.0
TH2_k127_4507358_21 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000000002798 134.0
TH2_k127_4507358_22 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000006561 125.0
TH2_k127_4507358_23 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000004347 92.0
TH2_k127_4507358_24 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000002777 80.0
TH2_k127_4507358_25 Staphylococcal nuclease homologue K01174 - 3.1.31.1 0.00000000009544 70.0
TH2_k127_4507358_26 RecX family K03565 - - 0.0000000003842 66.0
TH2_k127_4507358_27 - - - - 0.000007835 51.0
TH2_k127_4507358_29 ATP synthase, subunit b - - - 0.0008535 47.0
TH2_k127_4507358_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 610.0
TH2_k127_4507358_4 B3/4 domain K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 579.0
TH2_k127_4507358_5 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 550.0
TH2_k127_4507358_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 498.0
TH2_k127_4507358_7 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 499.0
TH2_k127_4507358_8 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 467.0
TH2_k127_4507358_9 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 432.0
TH2_k127_4508740_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.735e-231 724.0
TH2_k127_4514096_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.269e-258 818.0
TH2_k127_4514096_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.996e-198 623.0
TH2_k127_4514096_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 285.0
TH2_k127_4514096_11 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000006996 229.0
TH2_k127_4514096_12 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000000000000000000000001799 208.0
TH2_k127_4514096_13 nuclease activity - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000002922 196.0
TH2_k127_4514096_14 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000000005756 186.0
TH2_k127_4514096_15 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000006017 167.0
TH2_k127_4514096_16 Nucleotidyltransferase domain - - - 0.000000000000000000000000000002722 124.0
TH2_k127_4514096_17 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000006937 126.0
TH2_k127_4514096_18 positive regulation of growth - - - 0.000000000000000000002688 100.0
TH2_k127_4514096_19 - - - - 0.0000000000001811 72.0
TH2_k127_4514096_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 574.0
TH2_k127_4514096_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 440.0
TH2_k127_4514096_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 369.0
TH2_k127_4514096_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 354.0
TH2_k127_4514096_6 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 340.0
TH2_k127_4514096_7 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 330.0
TH2_k127_4514096_8 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 323.0
TH2_k127_4514096_9 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 316.0
TH2_k127_4521889_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 576.0
TH2_k127_4521889_1 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 488.0
TH2_k127_4521889_10 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000001187 246.0
TH2_k127_4521889_11 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000003638 219.0
TH2_k127_4521889_12 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000006364 217.0
TH2_k127_4521889_13 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.0000000000000000000000000000000000000000000000000000000008775 205.0
TH2_k127_4521889_14 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000006624 194.0
TH2_k127_4521889_15 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000113 197.0
TH2_k127_4521889_16 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000002096 177.0
TH2_k127_4521889_17 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000003884 164.0
TH2_k127_4521889_18 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000002686 134.0
TH2_k127_4521889_19 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000001825 120.0
TH2_k127_4521889_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 476.0
TH2_k127_4521889_20 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000006748 101.0
TH2_k127_4521889_21 Protein of unknown function (DUF2905) - - - 0.000000000000004185 79.0
TH2_k127_4521889_22 PFAM Methyltransferase type - - - 0.0000000004379 64.0
TH2_k127_4521889_24 N-acetylmuramoyl-L-alanine amidase - - - 0.00002509 54.0
TH2_k127_4521889_3 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 427.0
TH2_k127_4521889_4 Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 417.0
TH2_k127_4521889_5 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 393.0
TH2_k127_4521889_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 377.0
TH2_k127_4521889_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 346.0
TH2_k127_4521889_8 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003279 287.0
TH2_k127_4521889_9 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02236,K02278,K02506,K02654,K10966 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000002093 255.0
TH2_k127_4526610_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 379.0
TH2_k127_4526610_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 367.0
TH2_k127_4527312_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1035.0
TH2_k127_4527312_1 4Fe-4S binding domain - - - 1.187e-215 680.0
TH2_k127_4527312_10 Acyl transferase domain K00645,K15327,K15329,K15469 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009613 306.0
TH2_k127_4527312_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005853 284.0
TH2_k127_4527312_12 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000002774 260.0
TH2_k127_4527312_13 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001377 237.0
TH2_k127_4527312_14 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000002755 229.0
TH2_k127_4527312_15 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000901 208.0
TH2_k127_4527312_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000004448 197.0
TH2_k127_4527312_17 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000008119 162.0
TH2_k127_4527312_18 radical SAM K06871 - - 0.00000000000000000000000000000000000000001046 166.0
TH2_k127_4527312_19 - K07112 - - 0.0000000000000000000000000000000000000001248 160.0
TH2_k127_4527312_2 sister chromatid segregation - - - 8.895e-204 647.0
TH2_k127_4527312_20 Sulphur transport - - - 0.00000000000000000000000000000000000002137 149.0
TH2_k127_4527312_21 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000000988 135.0
TH2_k127_4527312_23 electron transfer activity K00428 - 1.11.1.5 0.00000000000000000000001395 105.0
TH2_k127_4527312_24 transferase activity, transferring acyl groups K03824 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000000000000001878 103.0
TH2_k127_4527312_25 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000001447 99.0
TH2_k127_4527312_26 - - - - 0.0000000000000000006991 87.0
TH2_k127_4527312_27 Putative zinc-finger - - - 0.0000000000000003198 89.0
TH2_k127_4527312_28 - - - - 0.00003201 52.0
TH2_k127_4527312_29 cytochrome C - - - 0.0001269 53.0
TH2_k127_4527312_3 Domain of unknown function (DUF4139) - - - 7.793e-202 639.0
TH2_k127_4527312_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.111e-200 637.0
TH2_k127_4527312_5 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 1.301e-200 636.0
TH2_k127_4527312_6 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 496.0
TH2_k127_4527312_7 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 401.0
TH2_k127_4527312_8 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 338.0
TH2_k127_4527312_9 PFAM Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 311.0
TH2_k127_4541867_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.802e-239 750.0
TH2_k127_4541867_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 522.0
TH2_k127_4541867_10 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000008292 176.0
TH2_k127_4541867_11 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000002039 173.0
TH2_k127_4541867_12 MgtC family K07507 - - 0.000000000000000000000000000000000000002775 154.0
TH2_k127_4541867_13 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000002595 151.0
TH2_k127_4541867_14 - - - - 0.00000000000000000000008225 102.0
TH2_k127_4541867_15 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00001005 49.0
TH2_k127_4541867_16 TPR repeat - - - 0.00004 56.0
TH2_k127_4541867_2 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 514.0
TH2_k127_4541867_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 471.0
TH2_k127_4541867_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 418.0
TH2_k127_4541867_5 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 361.0
TH2_k127_4541867_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001611 283.0
TH2_k127_4541867_7 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000006279 265.0
TH2_k127_4541867_8 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000001205 194.0
TH2_k127_4541867_9 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000001036 177.0
TH2_k127_4543803_0 PFAM Integrase core domain - - - 1.991e-199 633.0
TH2_k127_4543803_1 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 323.0
TH2_k127_456017_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004362 273.0
TH2_k127_456017_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000113 187.0
TH2_k127_456017_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000004858 134.0
TH2_k127_456017_3 response regulator, receiver - - - 0.00000000000000000000000003642 111.0
TH2_k127_456017_4 Histidine kinase - - - 0.0000005522 59.0
TH2_k127_4567573_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1103.0
TH2_k127_4567573_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1021.0
TH2_k127_4567573_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000003003 246.0
TH2_k127_4567573_11 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000002183 216.0
TH2_k127_4567573_12 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000001376 209.0
TH2_k127_4567573_13 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000002356 154.0
TH2_k127_4567573_14 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000001576 144.0
TH2_k127_4567573_15 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000000000000001983 143.0
TH2_k127_4567573_16 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000001057 134.0
TH2_k127_4567573_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000001805 108.0
TH2_k127_4567573_19 PBP superfamily domain K05772 - - 0.00000000000457 68.0
TH2_k127_4567573_2 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 1.936e-194 614.0
TH2_k127_4567573_21 SEC-C Motif Domain Protein - - - 0.0000000006465 69.0
TH2_k127_4567573_3 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 571.0
TH2_k127_4567573_4 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 388.0
TH2_k127_4567573_5 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 303.0
TH2_k127_4567573_6 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 286.0
TH2_k127_4567573_7 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000914 275.0
TH2_k127_4567573_8 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007117 272.0
TH2_k127_4567573_9 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005477 261.0
TH2_k127_4577441_0 radical SAM domain protein - - - 0.0000000000000000000000000000000001062 138.0
TH2_k127_4577441_1 Outer membrane lipoprotein LolB - - - 0.0004093 49.0
TH2_k127_4582591_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 451.0
TH2_k127_4582591_1 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000005086 87.0
TH2_k127_4614803_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000002479 212.0
TH2_k127_4614803_1 - - - - 0.00000000000000000000000000000000000000000000000000006233 198.0
TH2_k127_4614803_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000394 66.0
TH2_k127_4628791_0 Nitrate reductase, beta subunit K00371,K17051 - 1.7.5.1 2.192e-216 678.0
TH2_k127_4628791_1 TIGRFAM respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007271 276.0
TH2_k127_4628791_2 Transporter K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000178 271.0
TH2_k127_4628791_3 TIGRFAM nitrate reductase molybdenum cofactor assembly chaperone K00373 - - 0.0000000000000000000000000000000000000102 151.0
TH2_k127_4640616_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000000000000000000000000000001334 181.0
TH2_k127_4640616_1 - K18829 - - 0.000000000000000000000000000009457 119.0
TH2_k127_4640616_2 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000006507 74.0
TH2_k127_4641188_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 421.0
TH2_k127_4641188_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 326.0
TH2_k127_4641188_2 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 291.0
TH2_k127_4641188_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000001089 222.0
TH2_k127_4641188_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000004983 140.0
TH2_k127_4641188_5 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000003616 97.0
TH2_k127_4641188_6 integral membrane protein - - - 0.0000000342 65.0
TH2_k127_4670634_0 FAD binding domain K00278 - 1.4.3.16 3.642e-200 637.0
TH2_k127_4670634_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000744 596.0
TH2_k127_4670634_10 PFAM Cytochrome b5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 297.0
TH2_k127_4670634_11 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 293.0
TH2_k127_4670634_12 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005907 259.0
TH2_k127_4670634_13 cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004316 259.0
TH2_k127_4670634_14 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000006874 255.0
TH2_k127_4670634_15 TIGRFAM PAS domain S-box - - - 0.000000000000000000000000000000000000000000000000000000000000000000004771 256.0
TH2_k127_4670634_16 Protein of unknown function (DUF1460) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001794 237.0
TH2_k127_4670634_17 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000002786 232.0
TH2_k127_4670634_18 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000003639 224.0
TH2_k127_4670634_19 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000001961 234.0
TH2_k127_4670634_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 591.0
TH2_k127_4670634_20 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000004667 203.0
TH2_k127_4670634_21 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000006666 196.0
TH2_k127_4670634_22 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000001563 181.0
TH2_k127_4670634_23 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000004465 166.0
TH2_k127_4670634_24 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000001264 164.0
TH2_k127_4670634_25 Belongs to the SUA5 family K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000004284 165.0
TH2_k127_4670634_26 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000003243 155.0
TH2_k127_4670634_27 diguanylate cyclase - - - 0.00000000000000000000000000000000000004837 161.0
TH2_k127_4670634_28 4Fe-4S binding domain - - - 0.0000000000000000000000000000000004408 143.0
TH2_k127_4670634_29 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000002362 123.0
TH2_k127_4670634_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 541.0
TH2_k127_4670634_31 PFAM Phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.000000000000000000000000005599 113.0
TH2_k127_4670634_32 Binds the 23S rRNA K02909 - - 0.00000000000000000000000001488 109.0
TH2_k127_4670634_33 RNA-binding protein - - - 0.00000000000000000000000966 104.0
TH2_k127_4670634_34 Belongs to the heme-copper respiratory oxidase family K04561 - 1.7.2.5 0.00000000000000000000001007 106.0
TH2_k127_4670634_35 Protein of unknown function DUF262 - - - 0.000000000000000001403 89.0
TH2_k127_4670634_36 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000005139 83.0
TH2_k127_4670634_37 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000751 70.0
TH2_k127_4670634_38 methyl-accepting chemotaxis protein K03406 - - 0.0000000002832 64.0
TH2_k127_4670634_39 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00002869 48.0
TH2_k127_4670634_4 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 534.0
TH2_k127_4670634_5 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 535.0
TH2_k127_4670634_6 GHKL domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 532.0
TH2_k127_4670634_7 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 511.0
TH2_k127_4670634_8 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 483.0
TH2_k127_4670634_9 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 496.0
TH2_k127_4680057_0 regulation of translation K03530 - - 0.0000000000000000000000000000002338 125.0
TH2_k127_4682744_0 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000007728 191.0
TH2_k127_4682744_1 - - - - 0.000000000002279 72.0
TH2_k127_4696019_0 glucose sorbosone K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 319.0
TH2_k127_4764313_0 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000619 263.0
TH2_k127_4764313_1 - - - - 0.00000000000000000000000000000000265 141.0
TH2_k127_4764874_0 membrane K09790 - - 0.0000000000000000000002352 100.0
TH2_k127_4764874_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000002415 73.0
TH2_k127_4764874_2 Membrane transport protein K07088 - - 0.00002668 51.0
TH2_k127_4776949_0 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 342.0
TH2_k127_4776949_1 PFAM Transposase IS66 family K07484 - - 0.00000000000002011 81.0
TH2_k127_4776949_2 - - - - 0.000000000493 66.0
TH2_k127_4820998_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 500.0
TH2_k127_4820998_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 426.0
TH2_k127_4820998_2 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007388 420.0
TH2_k127_4820998_3 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000001498 175.0
TH2_k127_4820998_4 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000001253 123.0
TH2_k127_4822611_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000007552 95.0
TH2_k127_4822611_1 TIGRFAM cytochrome C family protein - - - 0.00001848 54.0
TH2_k127_4851966_0 FtsX-like permease family K02004 - - 5.073e-314 979.0
TH2_k127_4851966_1 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 417.0
TH2_k127_4851966_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 352.0
TH2_k127_4869703_0 PFAM transposase IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000118 223.0
TH2_k127_4869703_1 Belongs to the 'phage' integrase family - - - 0.00000000002734 65.0
TH2_k127_4870730_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.484e-209 659.0
TH2_k127_4870730_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 597.0
TH2_k127_4870730_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000001344 213.0
TH2_k127_4870730_11 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000003799 203.0
TH2_k127_4870730_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000823 203.0
TH2_k127_4870730_13 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000003471 181.0
TH2_k127_4870730_14 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000001764 177.0
TH2_k127_4870730_15 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000001779 179.0
TH2_k127_4870730_16 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000001458 165.0
TH2_k127_4870730_17 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000000004827 164.0
TH2_k127_4870730_18 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000009613 151.0
TH2_k127_4870730_19 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000000000000008783 130.0
TH2_k127_4870730_2 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 480.0
TH2_k127_4870730_20 Ribosomal protein L36 K02919 - - 0.0000000000003255 69.0
TH2_k127_4870730_21 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000004922 62.0
TH2_k127_4870730_22 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000005293 64.0
TH2_k127_4870730_3 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 361.0
TH2_k127_4870730_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 356.0
TH2_k127_4870730_5 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 319.0
TH2_k127_4870730_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 285.0
TH2_k127_4870730_7 cytochrome complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000001226 244.0
TH2_k127_4870730_8 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000003433 238.0
TH2_k127_4870730_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001414 229.0
TH2_k127_4870796_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1221.0
TH2_k127_4870796_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 384.0
TH2_k127_4870796_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000002473 233.0
TH2_k127_4870796_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.0000000000000000000000000000000000000000000000000000000000000663 220.0
TH2_k127_4870796_4 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000003303 216.0
TH2_k127_4870796_5 Belongs to the small heat shock protein (HSP20) family K06335,K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.00000000000000000000000000000000003723 139.0
TH2_k127_4870796_6 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000006673 136.0
TH2_k127_4881054_0 PFAM transposase mutator type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 547.0
TH2_k127_4881054_1 mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 340.0
TH2_k127_4890745_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 522.0
TH2_k127_4890745_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 316.0
TH2_k127_4890745_2 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000124 251.0
TH2_k127_4892216_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 430.0
TH2_k127_4892216_1 Protein of unknown function (DUF2726) - - - 0.000000000000000000000000007012 113.0
TH2_k127_4892216_2 - - - - 0.000000000000000000005388 96.0
TH2_k127_4896086_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1140.0
TH2_k127_4896086_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 2.236e-227 720.0
TH2_k127_4896086_10 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 381.0
TH2_k127_4896086_11 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 371.0
TH2_k127_4896086_12 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 355.0
TH2_k127_4896086_13 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 312.0
TH2_k127_4896086_14 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 307.0
TH2_k127_4896086_15 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 292.0
TH2_k127_4896086_16 CO dehydrogenase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 293.0
TH2_k127_4896086_17 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001759 281.0
TH2_k127_4896086_18 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001626 279.0
TH2_k127_4896086_19 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002078 281.0
TH2_k127_4896086_2 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 9.506e-214 683.0
TH2_k127_4896086_20 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005277 270.0
TH2_k127_4896086_21 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004863 268.0
TH2_k127_4896086_22 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000001996 235.0
TH2_k127_4896086_23 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000002127 240.0
TH2_k127_4896086_24 NAD(P)H dehydrogenase K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000002219 220.0
TH2_k127_4896086_25 Pfam:TPM K08988 - - 0.00000000000000000000000000000000000000000000000000000000007941 210.0
TH2_k127_4896086_26 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000006361 193.0
TH2_k127_4896086_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.0000000000000000000000000000000000000000000000001065 183.0
TH2_k127_4896086_28 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000008091 178.0
TH2_k127_4896086_29 AI-2E family transporter - - - 0.0000000000000000000000000000000000316 148.0
TH2_k127_4896086_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.512e-202 644.0
TH2_k127_4896086_30 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000001602 139.0
TH2_k127_4896086_31 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000001574 126.0
TH2_k127_4896086_32 PFAM Mammalian cell entry related K02067 - - 0.000000000000000000004508 104.0
TH2_k127_4896086_33 anti-sigma regulatory factor K04757 - 2.7.11.1 0.00000000000000000003353 95.0
TH2_k127_4896086_34 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000009543 84.0
TH2_k127_4896086_35 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000001298 91.0
TH2_k127_4896086_36 antisigma factor binding K04749 - - 0.000000000000001762 81.0
TH2_k127_4896086_37 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000002191 61.0
TH2_k127_4896086_39 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00009355 52.0
TH2_k127_4896086_4 Ftsk_gamma K03466 - - 3.883e-196 635.0
TH2_k127_4896086_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 585.0
TH2_k127_4896086_6 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 514.0
TH2_k127_4896086_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 490.0
TH2_k127_4896086_8 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 448.0
TH2_k127_4896086_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 394.0
TH2_k127_4929869_0 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 1.67e-278 872.0
TH2_k127_4929869_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 5.049e-250 781.0
TH2_k127_4929869_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 1.375e-219 687.0
TH2_k127_4929869_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 7.759e-207 650.0
TH2_k127_4929869_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 558.0
TH2_k127_4929869_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 512.0
TH2_k127_4929869_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.000000000000000000000000000000000000000000000000001357 188.0
TH2_k127_4944713_0 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 507.0
TH2_k127_4944713_1 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 329.0
TH2_k127_4944713_2 phosphoribosylformylglycinamidine synthase activity K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009507,GO:0009532,GO:0009536,GO:0009555,GO:0009570,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048229,GO:0048856,GO:0055046,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.000000000000000000009717 91.0
TH2_k127_4970890_0 Homeodomain-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 425.0
TH2_k127_4970890_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 324.0
TH2_k127_4970890_2 Belongs to the sirtuin family. Class K12410 - - 0.000000000000000000000000000000000000000000002854 168.0
TH2_k127_4970890_4 PFAM transposase IS116 IS110 IS902 family - - - 0.0000000000006473 69.0
TH2_k127_5064690_0 Protein of unknown function DUF126 K09123,K09128 - - 0.00000000000000000000000000000000000002561 147.0
TH2_k127_5064690_1 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.00000000000000000000000000001067 119.0
TH2_k127_5064690_2 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000007244 91.0
TH2_k127_5104369_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 3.636e-321 997.0
TH2_k127_5104369_1 FAD dependent oxidoreductase K16885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 576.0
TH2_k127_5104369_2 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001968 286.0
TH2_k127_5145147_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000004845 148.0
TH2_k127_5145147_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000007179 91.0
TH2_k127_5154084_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 507.0
TH2_k127_5154084_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000002895 212.0
TH2_k127_5154084_2 Belongs to the pseudouridine synthase RluA family - - - 0.00000000000000000000000000000000000000000000000000000000004375 210.0
TH2_k127_5262650_0 HEPN domain - - - 0.0000000000000000000000000009205 117.0
TH2_k127_5262650_1 4Fe-4S binding domain - - - 0.00000000000000001933 83.0
TH2_k127_5262650_2 Nucleotidyltransferase domain - - - 0.000000989 55.0
TH2_k127_5383488_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 8.235e-218 682.0
TH2_k127_5383488_1 Integrase core domain - - - 0.0000000000000000000000001057 112.0
TH2_k127_5383488_2 transposase activity K07483 - - 0.0000000000000000000000002981 108.0
TH2_k127_5383488_4 transposition K07497 - - 0.000000000000000001344 89.0
TH2_k127_5383488_5 - - - - 0.0001341 45.0
TH2_k127_5440812_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1269.0
TH2_k127_5440812_1 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000000000000000001695 122.0
TH2_k127_5440812_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000001015 78.0
TH2_k127_545279_0 DEAD-like helicases superfamily - - - 0.0 1223.0
TH2_k127_545279_1 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 386.0
TH2_k127_5513882_0 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 330.0
TH2_k127_5513882_1 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003086 259.0
TH2_k127_557619_0 DEAD DEAH box helicase K06877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 510.0
TH2_k127_557619_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 420.0
TH2_k127_557619_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001548 275.0
TH2_k127_557619_3 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000008626 176.0
TH2_k127_557619_4 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000002102 147.0
TH2_k127_557619_5 PilZ domain - - - 0.0000478 49.0
TH2_k127_5577343_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.917e-224 704.0
TH2_k127_5577343_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 399.0
TH2_k127_5577343_2 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 390.0
TH2_k127_5577343_3 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000008093 239.0
TH2_k127_5577343_4 - - - - 0.0000000000000000000000000000000000000000000000000006449 188.0
TH2_k127_5577343_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000008117 185.0
TH2_k127_5577343_6 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000008562 130.0
TH2_k127_5577343_7 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.0000000000000000000000177 104.0
TH2_k127_5577343_8 PFAM Cobalt transport protein K02007,K02008 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0001668 44.0
TH2_k127_5578145_0 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000002233 190.0
TH2_k127_5578145_1 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000000000000000000000000005644 155.0
TH2_k127_5578145_2 PFAM Transposase IS200-like K07491 - - 0.000000000000000000000000000000000000001141 151.0
TH2_k127_5578145_3 - - - - 0.000002064 51.0
TH2_k127_5587303_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002701 250.0
TH2_k127_5587303_1 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.00000000000000000000000000009984 123.0
TH2_k127_5587303_2 4Fe-4S binding domain - - - 0.000000000001493 70.0
TH2_k127_5587303_3 4Fe-4S dicluster domain - - - 0.000005307 51.0
TH2_k127_5595054_0 Bacterial protein of unknown function (DUF853) K06915 - - 2.141e-216 680.0
TH2_k127_5595054_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 602.0
TH2_k127_5595054_2 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000001335 168.0
TH2_k127_5595054_3 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000002203 165.0
TH2_k127_5595054_4 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000002235 158.0
TH2_k127_5595054_5 - - - - 0.000000000000000000000000002688 115.0
TH2_k127_5595054_6 PFAM CBS domain - - - 0.000000000000000000000001299 111.0
TH2_k127_5595054_8 PFAM response regulator receiver K02483 - - 0.000005234 56.0
TH2_k127_5601220_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000004083 223.0
TH2_k127_5601220_1 YtkA-like - - - 0.00000000000000000000000000000009304 132.0
TH2_k127_56092_0 Belongs to the bacterial glucokinase family K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 441.0
TH2_k127_56092_1 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 310.0
TH2_k127_56092_2 Possible lysine decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008222 278.0
TH2_k127_56092_3 Ion channel - - - 0.0000000008023 65.0
TH2_k127_5630776_0 Cytochrome c K08738 - - 0.0000000000000006547 83.0
TH2_k127_5630776_1 Cytochrome c - - - 0.0000000000000166 76.0
TH2_k127_5630776_2 electron transfer activity K00428 - 1.11.1.5 0.000002375 54.0
TH2_k127_5656268_0 Helix-turn-helix domain protein - - - 0.000000000000000000000000000000744 127.0
TH2_k127_5677423_0 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 504.0
TH2_k127_5677423_1 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 371.0
TH2_k127_5677423_2 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 364.0
TH2_k127_5677423_3 CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 356.0
TH2_k127_5677423_4 exo-alpha-(2->6)-sialidase activity - - - 0.0000007365 52.0
TH2_k127_5684126_0 PFAM ribonuclease II K01147 - 3.1.13.1 4.557e-213 672.0
TH2_k127_5684126_1 Cytochrome c - - - 1.148e-196 621.0
TH2_k127_5698769_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 338.0
TH2_k127_5698769_1 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000000001255 151.0
TH2_k127_5698769_2 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000726 134.0
TH2_k127_5698769_3 Membrane transport protein K07088 - - 0.0000004717 58.0
TH2_k127_5706660_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 1.527e-211 670.0
TH2_k127_5706660_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 349.0
TH2_k127_5706660_2 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000001374 132.0
TH2_k127_5706660_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000001768 103.0
TH2_k127_5706660_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000001501 87.0
TH2_k127_5706660_5 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000008017 68.0
TH2_k127_5718954_0 ABC-type sugar transport system periplasmic component K17321 - - 8.089e-229 722.0
TH2_k127_5718954_1 ATPases associated with a variety of cellular activities K17325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 393.0
TH2_k127_5718954_2 Binding-protein-dependent transport system inner membrane component K17323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 385.0
TH2_k127_5718954_3 ATPases associated with a variety of cellular activities K17324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 380.0
TH2_k127_5718954_4 Binding-protein-dependent transport system inner membrane component K02025,K17322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 352.0
TH2_k127_5718954_5 Predicted small integral membrane protein (DUF2160) - - - 0.00000000000000001726 86.0
TH2_k127_5718954_6 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00008 - 1.1.1.14 0.000000004797 58.0
TH2_k127_5719082_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 5.248e-214 672.0
TH2_k127_5719082_1 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 407.0
TH2_k127_5719082_10 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000001508 173.0
TH2_k127_5719082_11 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000001549 127.0
TH2_k127_5719082_12 Domain of unknown function (DUF370) K09777 - - 0.000000000000000000000000001182 117.0
TH2_k127_5719082_13 Roadblock/LC7 domain - - - 0.00000000000000000004431 94.0
TH2_k127_5719082_14 Tetratricopeptide repeat - - - 0.00000000000000000008921 102.0
TH2_k127_5719082_15 Belongs to the 'phage' integrase family - - - 0.000000000248 61.0
TH2_k127_5719082_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 372.0
TH2_k127_5719082_3 Metallopeptidase family M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007279 287.0
TH2_k127_5719082_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000004494 236.0
TH2_k127_5719082_5 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000001536 213.0
TH2_k127_5719082_6 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000001252 196.0
TH2_k127_5719082_7 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000001837 191.0
TH2_k127_5719082_8 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000002428 179.0
TH2_k127_5719082_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000008498 172.0
TH2_k127_5719214_0 PFAM Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 484.0
TH2_k127_5719214_1 PFAM IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 310.0
TH2_k127_5719214_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000002111 239.0
TH2_k127_5761384_0 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 366.0
TH2_k127_5761384_1 TIGRFAM TIGR00268 family protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002999 271.0
TH2_k127_5761384_2 lactate metabolic process K11473,K18928 - - 0.00000000000000000000000000000000000000000000000001187 190.0
TH2_k127_5779989_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 465.0
TH2_k127_5788768_0 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003973 283.0
TH2_k127_5788768_1 - - - - 0.000000000002391 71.0
TH2_k127_5792248_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008516 471.0
TH2_k127_5792248_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000004334 223.0
TH2_k127_5796726_0 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005083 298.0
TH2_k127_5796726_1 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000002082 216.0
TH2_k127_5796726_2 Protein of unknown function (DUF2892) - - - 0.000000000000385 76.0
TH2_k127_5818178_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 290.0
TH2_k127_5818178_1 coenzyme F420 binding K00275 - 1.4.3.5 0.0000000000000000000000000000000000003584 145.0
TH2_k127_5818178_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000001004 67.0
TH2_k127_5830508_0 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 374.0
TH2_k127_5830508_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002554 245.0
TH2_k127_5830508_2 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000546 170.0
TH2_k127_5830508_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000001815 114.0
TH2_k127_5831_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 419.0
TH2_k127_5831_1 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002362 239.0
TH2_k127_5832896_0 cell redox homeostasis - - - 7.279e-204 644.0
TH2_k127_5832896_1 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 322.0
TH2_k127_5832896_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 316.0
TH2_k127_5832896_3 Protein of unknown function (DUF3047) - - - 0.0000000000000000003048 88.0
TH2_k127_5839888_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 1.246e-247 777.0
TH2_k127_5839888_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 2.197e-213 674.0
TH2_k127_5839888_10 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003666 254.0
TH2_k127_5839888_11 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000002407 177.0
TH2_k127_5839888_12 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000007284 154.0
TH2_k127_5839888_13 cyclic nucleotide-binding - - - 0.000000000000000000000000000003805 124.0
TH2_k127_5839888_14 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000001596 123.0
TH2_k127_5839888_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 2.25e-197 629.0
TH2_k127_5839888_3 NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335 K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 3.142e-196 628.0
TH2_k127_5839888_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 598.0
TH2_k127_5839888_5 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 478.0
TH2_k127_5839888_6 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 445.0
TH2_k127_5839888_7 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 322.0
TH2_k127_5839888_8 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005177 271.0
TH2_k127_5839888_9 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000007719 251.0
TH2_k127_5842742_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 5.66e-201 640.0
TH2_k127_5878627_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 469.0
TH2_k127_5878627_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 451.0
TH2_k127_5878627_2 histidine kinase A domain protein - - - 0.00000000000000000000000000000007425 138.0
TH2_k127_5878627_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000002347 115.0
TH2_k127_5878627_4 Single-strand binding protein family K03111 - - 0.00000000000000000000000005554 108.0
TH2_k127_5878627_5 response regulator K14979 - - 0.00000000002517 75.0
TH2_k127_5882774_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 3.898e-252 790.0
TH2_k127_5882774_1 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 472.0
TH2_k127_5882774_2 Molybdopterin oxidoreductase, Fe4S4 K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 446.0
TH2_k127_5882774_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000004809 184.0
TH2_k127_5891059_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 556.0
TH2_k127_5891059_1 PFAM 4Fe-4S K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 428.0
TH2_k127_5898226_0 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage K03497 - - 0.0000000000000000000000000005364 130.0
TH2_k127_5898226_1 - - - - 0.00000000000000000000000002123 119.0
TH2_k127_5898226_2 DNA synthesis involved in double-strand break repair via homologous recombination K07455 - - 0.00000000000000004898 91.0
TH2_k127_596197_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 523.0
TH2_k127_596197_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 389.0
TH2_k127_596197_2 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 341.0
TH2_k127_596197_3 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000003593 231.0
TH2_k127_596197_4 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000001974 213.0
TH2_k127_596197_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000001177 209.0
TH2_k127_596197_6 PFAM Fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000001834 173.0
TH2_k127_596197_7 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.000000000000000000000000000000000000004057 148.0
TH2_k127_596197_8 Uncharacterized protein conserved in bacteria (DUF2064) K09931,K20742 - 3.4.14.13 0.0000000000000000000000000000000003887 142.0
TH2_k127_6051626_0 PFAM transposase, mutator K07493 - - 0.000000000000000000000000000000000000000000000000000000000000009017 229.0
TH2_k127_6102573_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 368.0
TH2_k127_6102573_1 protein related to deoxyribodipyrimidine photolyase K06876 - - 0.0001024 46.0
TH2_k127_6102573_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0005285 46.0
TH2_k127_6143238_0 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 375.0
TH2_k127_6143238_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K19516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001291 264.0
TH2_k127_6147068_0 Peptidase family M28 - - - 0.0 1096.0
TH2_k127_6147068_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5.815e-279 872.0
TH2_k127_6147068_10 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 419.0
TH2_k127_6147068_11 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 378.0
TH2_k127_6147068_12 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 371.0
TH2_k127_6147068_13 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001203 279.0
TH2_k127_6147068_14 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000001996 261.0
TH2_k127_6147068_15 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000005122 237.0
TH2_k127_6147068_16 Mo-molybdopterin cofactor metabolic process K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000001767 231.0
TH2_k127_6147068_17 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000004793 190.0
TH2_k127_6147068_18 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000001857 175.0
TH2_k127_6147068_19 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000166 159.0
TH2_k127_6147068_2 General secretory system II, protein E domain protein K02652 - - 1.967e-213 680.0
TH2_k127_6147068_20 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000008327 107.0
TH2_k127_6147068_21 domain protein - - - 0.00000000000000000000006027 108.0
TH2_k127_6147068_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000002312 99.0
TH2_k127_6147068_23 electron transfer activity K00428 - 1.11.1.5 0.00000000000000003246 85.0
TH2_k127_6147068_25 Transposase IS200 like K07491 - - 0.00000000248 62.0
TH2_k127_6147068_26 serine-type endopeptidase activity K20276 - - 0.000001183 52.0
TH2_k127_6147068_28 PIN domain - - - 0.0001742 47.0
TH2_k127_6147068_3 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 602.0
TH2_k127_6147068_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008983 577.0
TH2_k127_6147068_5 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 554.0
TH2_k127_6147068_6 Beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 526.0
TH2_k127_6147068_7 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 530.0
TH2_k127_6147068_8 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 518.0
TH2_k127_6147068_9 phosphorelay signal transduction system K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 457.0
TH2_k127_61579_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 502.0
TH2_k127_61579_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 340.0
TH2_k127_61579_10 Cna B domain protein - - - 0.000001548 61.0
TH2_k127_61579_11 iron ion homeostasis - - - 0.000207 52.0
TH2_k127_61579_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001218 265.0
TH2_k127_61579_3 O-Antigen ligase K02847 - - 0.000000000000000000000000000000000000000000000000000000201 212.0
TH2_k127_61579_4 PFAM PHP domain protein K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000008634 184.0
TH2_k127_61579_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000001589 187.0
TH2_k127_61579_6 Polysaccharide export protein K01991 - - 0.000000000000000000000000000000000000000005225 169.0
TH2_k127_61579_7 KOW (Kyprides, Ouzounis, Woese) motif. K05785 - - 0.000000000000000000000000000000005864 133.0
TH2_k127_61579_8 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000003843 83.0
TH2_k127_61579_9 DnaJ molecular chaperone homology domain K05516 - - 0.000000002723 70.0
TH2_k127_6272198_0 GTP-binding protein TypA K06207 - - 1.695e-259 810.0
TH2_k127_6272198_1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus K00341 - 1.6.5.3 1.196e-244 770.0
TH2_k127_6272198_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000002241 128.0
TH2_k127_6272198_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000002504 96.0
TH2_k127_6272198_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 613.0
TH2_k127_6272198_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 556.0
TH2_k127_6272198_4 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 527.0
TH2_k127_6272198_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 465.0
TH2_k127_6272198_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 419.0
TH2_k127_6272198_7 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.00000000000000000000000000000000000000001488 157.0
TH2_k127_6272198_8 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000197 153.0
TH2_k127_6272198_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000003314 151.0
TH2_k127_6274474_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1121.0
TH2_k127_6274474_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 3.96e-316 972.0
TH2_k127_6274474_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 1.537e-204 652.0
TH2_k127_6274474_3 PFAM Glutamine amidotransferase, class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 296.0
TH2_k127_6274474_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000002925 229.0
TH2_k127_644846_0 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001323 271.0
TH2_k127_644846_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000006836 243.0
TH2_k127_644846_2 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000002567 228.0
TH2_k127_6590549_0 Transposase domain (DUF772) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 435.0
TH2_k127_67004_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1582.0
TH2_k127_67004_1 Transport of potassium into the cell K03549 - - 2.939e-242 762.0
TH2_k127_67004_10 protein with SCP PR1 domains - - - 0.000000000000000000000000000000000000000000405 166.0
TH2_k127_67004_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 593.0
TH2_k127_67004_3 PFAM phosphofructokinase K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 534.0
TH2_k127_67004_4 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 514.0
TH2_k127_67004_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 487.0
TH2_k127_67004_6 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 372.0
TH2_k127_67004_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000005791 228.0
TH2_k127_67004_8 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000005734 228.0
TH2_k127_67004_9 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000000000007825 169.0
TH2_k127_6711562_0 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 353.0
TH2_k127_6711562_1 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000306 237.0
TH2_k127_6711562_2 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000001242 199.0
TH2_k127_6711562_3 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000000928 119.0
TH2_k127_6726473_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 539.0
TH2_k127_6726473_1 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 347.0
TH2_k127_6726473_2 - - - - 0.00000000000000000000000000000000000000000000000006242 182.0
TH2_k127_6726473_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000001292 160.0
TH2_k127_6743831_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 525.0
TH2_k127_6743831_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 304.0
TH2_k127_6743831_2 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005126 279.0
TH2_k127_6743831_3 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000009308 163.0
TH2_k127_6743831_4 LETM1-like protein - - - 0.00002545 50.0
TH2_k127_6769344_0 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000006822 206.0
TH2_k127_6769344_1 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000002551 85.0
TH2_k127_6784928_0 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000002221 215.0
TH2_k127_6784928_1 membrane K09790 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000002958 98.0
TH2_k127_6792529_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.078e-226 719.0
TH2_k127_6792529_1 Phosphate-starvation-inducible E - - - 0.000000000000000000000000000000000000000005131 158.0
TH2_k127_6863584_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 6.501e-317 994.0
TH2_k127_6863584_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 3.75e-218 692.0
TH2_k127_6863584_2 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 419.0
TH2_k127_6863584_3 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 389.0
TH2_k127_6897667_0 Sigma-54 interaction domain K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 436.0
TH2_k127_6897667_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001382 254.0
TH2_k127_6897667_2 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006539 240.0
TH2_k127_6897667_3 GAF domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000008287 259.0
TH2_k127_6897667_4 nitric oxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000003165 216.0
TH2_k127_6897667_5 - - - - 0.000000000000000000000000000000000000000000007284 167.0
TH2_k127_6897667_6 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000000000000185 137.0
TH2_k127_6897667_7 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.00000003203 61.0
TH2_k127_6899682_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1213.0
TH2_k127_6899682_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000002734 232.0
TH2_k127_6899682_2 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000262 124.0
TH2_k127_6914984_0 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 502.0
TH2_k127_6965981_0 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 362.0
TH2_k127_6965981_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000219 288.0
TH2_k127_6965981_2 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000005103 154.0
TH2_k127_6975397_0 PFAM Type II IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 396.0
TH2_k127_6975397_1 PFAM Type II IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 368.0
TH2_k127_6981746_0 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 400.0
TH2_k127_6981746_1 COGs COG3328 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000004098 141.0
TH2_k127_6981746_2 Transposase - - - 0.0000000000000982 72.0
TH2_k127_6981746_3 Excisionase - - - 0.00001125 51.0
TH2_k127_6981746_4 transposase activity K07483,K07497 - - 0.00001749 48.0
TH2_k127_6998017_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 414.0
TH2_k127_6998017_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000009825 149.0
TH2_k127_6998017_2 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000000000000000000000000000004615 142.0
TH2_k127_7037674_0 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 470.0
TH2_k127_7037674_1 PAS fold - - - 0.00000000000000000000000000000000000000000000000001001 188.0
TH2_k127_7037674_2 transposase activity K07483,K07497 - - 0.0000000000000000000003955 98.0
TH2_k127_7075813_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 5.017e-253 789.0
TH2_k127_7089403_0 Protein export membrane protein K07003 - - 0.000000000000000000000000000000000000000000000000000001611 217.0
TH2_k127_7089403_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000007807 159.0
TH2_k127_7089403_2 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000001367 113.0
TH2_k127_7089403_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000001596 102.0
TH2_k127_7089403_4 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.000000000157 66.0
TH2_k127_7089403_5 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000002561 58.0
TH2_k127_7127735_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 492.0
TH2_k127_7127735_1 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000001415 168.0
TH2_k127_7127735_2 MgtC family K07507 - - 0.000000000000000000000000000000000000119 149.0
TH2_k127_7127735_3 - - - - 0.000000000000000000000000001027 117.0
TH2_k127_7136823_0 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000005068 202.0
TH2_k127_7136823_1 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000000008034 151.0
TH2_k127_7136823_2 GIY-YIG catalytic domain K07461 - - 0.0000000000000009668 79.0
TH2_k127_7138070_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 1.938e-276 862.0
TH2_k127_7138070_1 Glycosyl hydrolases family 43 - - - 0.00000000000000000000000000001053 126.0
TH2_k127_7138070_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000004205 111.0
TH2_k127_7138070_3 Belongs to the glycosyl hydrolase 43 family - - - 0.00000000000003408 76.0
TH2_k127_7138070_4 His Kinase A (phosphoacceptor) domain - - - 0.000002018 52.0
TH2_k127_7155660_0 Methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 362.0
TH2_k127_7155660_1 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008327 251.0
TH2_k127_7155660_2 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000009296 95.0
TH2_k127_7159610_0 COG3328 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 585.0
TH2_k127_7159610_1 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000006628 197.0
TH2_k127_7160737_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1124.0
TH2_k127_7160737_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 8.627e-308 952.0
TH2_k127_7160737_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 391.0
TH2_k127_7160737_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 383.0
TH2_k127_7160737_4 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 340.0
TH2_k127_7201815_0 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000004482 214.0
TH2_k127_7201815_1 COG4584 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000002553 194.0
TH2_k127_7201815_2 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000000000000000000000000000000005987 138.0
TH2_k127_7201815_3 IstB-like ATP binding protein - - - 0.0000000000000000000000000001229 125.0
TH2_k127_7201815_4 Protein of unknown function (DUF3696) - - - 0.000000000001518 72.0
TH2_k127_7201815_5 - - - - 0.000000006063 62.0
TH2_k127_7201815_6 - - - - 0.0005772 48.0
TH2_k127_7238382_0 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000000000001229 200.0
TH2_k127_7238382_1 lytic transglycosylase activity - - - 0.00001506 47.0
TH2_k127_7238382_2 - - - - 0.0003676 45.0
TH2_k127_7271125_0 Phosphoglycerate kinase K00927 - 2.7.2.3 1.579e-195 616.0
TH2_k127_7271125_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 6.895e-195 615.0
TH2_k127_7271125_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 314.0
TH2_k127_7271125_11 metal ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000001983 235.0
TH2_k127_7271125_12 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000001517 224.0
TH2_k127_7271125_13 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000008005 212.0
TH2_k127_7271125_14 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000004117 207.0
TH2_k127_7271125_15 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000009692 162.0
TH2_k127_7271125_16 COGs COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000002956 161.0
TH2_k127_7271125_17 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000003507 132.0
TH2_k127_7271125_18 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000002119 134.0
TH2_k127_7271125_19 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000005434 94.0
TH2_k127_7271125_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 490.0
TH2_k127_7271125_20 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000005722 96.0
TH2_k127_7271125_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 491.0
TH2_k127_7271125_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 434.0
TH2_k127_7271125_5 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 421.0
TH2_k127_7271125_6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 404.0
TH2_k127_7271125_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 372.0
TH2_k127_7271125_8 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 369.0
TH2_k127_7271125_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 341.0
TH2_k127_7294619_0 Ferric uptake regulator family K09825 - - 0.00000000000000000000000000000000000004554 147.0
TH2_k127_7294619_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.000000000608 61.0
TH2_k127_7294619_2 Phage integrase, N-terminal SAM-like domain - - - 0.000002095 50.0
TH2_k127_7294619_3 HsdM N-terminal domain K03427 - 2.1.1.72 0.000009275 52.0
TH2_k127_7297790_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1237.0
TH2_k127_7297790_1 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 422.0
TH2_k127_7297790_2 PFAM 4Fe-4S binding domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009498 270.0
TH2_k127_7297790_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000003887 240.0
TH2_k127_7297790_4 DSBA-like thioredoxin domain - - - 0.0000000006814 60.0
TH2_k127_7297790_5 DSBA-like thioredoxin domain - - - 0.0000004155 54.0
TH2_k127_7309477_0 CreA protein K05805 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000005234 194.0
TH2_k127_7309477_1 Prolyl oligopeptidase family K00433 - 1.11.1.10 0.00000000000000000000000000000001001 130.0
TH2_k127_7309477_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000001835 128.0
TH2_k127_7309477_4 - - - - 0.0000003775 54.0
TH2_k127_7309477_5 Protein of unknown function (DUF2934) - - - 0.00007549 48.0
TH2_k127_7310512_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 480.0
TH2_k127_7310512_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 435.0
TH2_k127_7310512_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 366.0
TH2_k127_7310512_3 - - - - 0.000000000000000000000000000000000000001931 156.0
TH2_k127_7310512_4 - - - - 0.00000005773 61.0
TH2_k127_7340898_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 535.0
TH2_k127_7340898_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 368.0
TH2_k127_7340898_2 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000114 196.0
TH2_k127_7340898_3 Member of the two-component regulatory system AtoS AtoC. In the presence of acetoacetate, AtoS AtoC stimulates the expression of the atoDAEB operon, leading to short chain fatty acid catabolism and activation of the poly-(R)-3-hydroxybutyrate (cPHB) biosynthetic pathway. Also induces the operon in response to spermidine. Involved in the regulation of motility and chemotaxis, via transcriptional induction of the flagellar regulon. AtoS is a membrane-associated kinase that phosphorylates and activates AtoC in response to environmental signals K07710 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000009394 202.0
TH2_k127_7340898_4 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000004352 132.0
TH2_k127_7341690_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 375.0
TH2_k127_7341690_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 331.0
TH2_k127_7341690_10 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000005278 139.0
TH2_k127_7341690_11 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000001015 111.0
TH2_k127_7341690_12 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000006275 104.0
TH2_k127_7341690_13 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000285 105.0
TH2_k127_7341690_14 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000001436 82.0
TH2_k127_7341690_15 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000008361 74.0
TH2_k127_7341690_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 284.0
TH2_k127_7341690_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001147 280.0
TH2_k127_7341690_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001075 235.0
TH2_k127_7341690_5 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000003191 215.0
TH2_k127_7341690_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001061 202.0
TH2_k127_7341690_7 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000001257 169.0
TH2_k127_7341690_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000001646 160.0
TH2_k127_7341690_9 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000002349 140.0
TH2_k127_7388808_0 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 499.0
TH2_k127_7410596_0 Involved in initiation control of chromosome replication K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 386.0
TH2_k127_755585_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002752 265.0
TH2_k127_755585_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000296 159.0
TH2_k127_7694502_0 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 308.0
TH2_k127_7694502_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000008607 259.0
TH2_k127_7694502_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000002364 248.0
TH2_k127_7694502_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000002201 192.0
TH2_k127_7694502_4 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000002024 174.0
TH2_k127_7694502_5 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000003797 95.0
TH2_k127_7694502_6 YMGG-like Gly-zipper - - - 0.0000005584 60.0
TH2_k127_7694502_7 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.00006763 47.0
TH2_k127_7694502_8 Flagellar protein FlaF - - - 0.00007574 48.0
TH2_k127_780476_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 6.816e-217 679.0
TH2_k127_780476_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 617.0
TH2_k127_780476_10 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 292.0
TH2_k127_780476_11 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000002926 229.0
TH2_k127_780476_12 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000005792 197.0
TH2_k127_780476_13 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000005328 108.0
TH2_k127_780476_14 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000002744 102.0
TH2_k127_780476_15 23S rRNA-intervening sequence protein - - - 0.0000000000000005499 79.0
TH2_k127_780476_16 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000001494 75.0
TH2_k127_780476_17 23S rRNA-intervening sequence protein - - - 0.00000000002165 66.0
TH2_k127_780476_18 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0004185 44.0
TH2_k127_780476_2 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 508.0
TH2_k127_780476_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 480.0
TH2_k127_780476_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 477.0
TH2_k127_780476_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 434.0
TH2_k127_780476_6 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 428.0
TH2_k127_780476_7 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 405.0
TH2_k127_780476_8 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 317.0
TH2_k127_780476_9 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 314.0
TH2_k127_7869444_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 8.735e-254 803.0
TH2_k127_7869444_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 616.0
TH2_k127_7869444_2 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 298.0
TH2_k127_7869444_3 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000007705 251.0
TH2_k127_7869444_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000001272 231.0
TH2_k127_7869444_5 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000005923 144.0
TH2_k127_7869444_6 Transcriptional regulator, MerR family - - - 0.0000000000000000000000000000000001018 137.0
TH2_k127_7869444_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000007071 87.0
TH2_k127_7869444_8 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.00000000004398 76.0
TH2_k127_7924330_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 353.0
TH2_k127_7924330_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 337.0
TH2_k127_7924330_2 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000006254 242.0
TH2_k127_7924330_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000002749 168.0
TH2_k127_7924330_4 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000002038 166.0
TH2_k127_7924330_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000006718 109.0
TH2_k127_7924330_7 Protein of unknown function (DUF2934) - - - 0.0001219 48.0
TH2_k127_7971754_0 COGs COG1943 Transposase and inactivated derivatives K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003663 239.0
TH2_k127_7971754_1 Belongs to the N(4) N(6)-methyltransferase family - - - 0.0000000002719 68.0
TH2_k127_7972839_0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000001342 93.0
TH2_k127_7972839_1 MazG-like family - - - 0.00000000000001146 74.0
TH2_k127_7972839_2 CopG antitoxin of type II toxin-antitoxin system - - - 0.000000003829 61.0
TH2_k127_8017026_0 Molybdate transporter of MFS superfamily K03321 - - 0.00000000000000000000000000000000000000000000000000000000005594 221.0
TH2_k127_8017026_1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000838 156.0
TH2_k127_8017026_2 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000000007288 122.0
TH2_k127_8018010_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 4.61e-284 884.0
TH2_k127_8018010_1 Uncharacterised protein family (UPF0182) K09118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001378 265.0
TH2_k127_8018010_2 - - - - 0.000000000000000000000000000000000000000000000000000000000144 205.0
TH2_k127_8018010_3 PFAM Integrase core domain - - - 0.0000000002944 65.0
TH2_k127_8018010_4 SMART Elongator protein 3 MiaB NifB - - - 0.000002525 49.0
TH2_k127_8063850_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 1.44e-229 729.0
TH2_k127_8063850_1 TIGRFAM iron-sulfur cluster binding protein - - - 0.000000000000000000000000000000000000000000000000007506 187.0
TH2_k127_8063850_2 Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000005119 115.0
TH2_k127_8063850_3 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.0000000000000000005752 87.0
TH2_k127_8063850_4 - - - - 0.0000000000001704 74.0
TH2_k127_8063850_5 nitrate reductase activity - - - 0.00000032 61.0
TH2_k127_8082302_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.079e-306 953.0
TH2_k127_8101511_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000001504 136.0
TH2_k127_8133056_0 Aconitase C-terminal domain K01681 - 4.2.1.3 4.448e-300 932.0
TH2_k127_8133056_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 532.0
TH2_k127_8133056_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 444.0
TH2_k127_8133056_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 340.0
TH2_k127_8133056_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 316.0
TH2_k127_8259624_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 321.0
TH2_k127_8259624_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 311.0
TH2_k127_8259624_2 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000114 236.0
TH2_k127_8259624_3 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.0000000000000000000000000000000000000000000000000003086 196.0
TH2_k127_8259624_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000001052 180.0
TH2_k127_8259624_5 MICAL-like K19948 GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0006897,GO:0006898,GO:0007009,GO:0007275,GO:0007399,GO:0008092,GO:0008104,GO:0008150,GO:0008289,GO:0009719,GO:0009987,GO:0010008,GO:0010033,GO:0010256,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016192,GO:0016197,GO:0017016,GO:0017137,GO:0019898,GO:0019899,GO:0022008,GO:0030030,GO:0030154,GO:0030182,GO:0031090,GO:0031175,GO:0031267,GO:0031410,GO:0031902,GO:0031982,GO:0032456,GO:0032458,GO:0032501,GO:0032502,GO:0033036,GO:0033365,GO:0034613,GO:0036010,GO:0042221,GO:0042802,GO:0042886,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0048468,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0051020,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0055037,GO:0055038,GO:0061024,GO:0070300,GO:0070727,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071702,GO:0071705,GO:0071840,GO:0072657,GO:0090150,GO:0097320,GO:0097708,GO:0098588,GO:0098657,GO:0098805,GO:0098876,GO:0120036,GO:1990089,GO:1990090,GO:1990126 - 0.0009222 42.0
TH2_k127_8281581_0 Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 387.0
TH2_k127_8281581_1 Pfam Transposase K07483 - - 0.000000000000000000000000000000000000876 142.0
TH2_k127_8282574_0 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000004299 236.0
TH2_k127_8282574_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 0.0000000000000000000000000006376 115.0
TH2_k127_8309701_0 - - - - 0.00000000000000000000000000000000000000000000000000000000001915 217.0
TH2_k127_8309701_1 Phage integrase, N-terminal SAM-like domain - - - 0.000000001572 67.0
TH2_k127_8341823_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 394.0
TH2_k127_8341823_1 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000000000000000000000002541 225.0
TH2_k127_8341823_2 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000001839 202.0
TH2_k127_8341823_4 Cysteine rich repeat - - - 0.000000000000000000000000000000000005972 137.0
TH2_k127_8432628_0 Winged helix-turn helix - - - 0.0000000000000000008266 86.0
TH2_k127_8432628_1 - - - - 0.00000000000009381 78.0
TH2_k127_8432628_2 Alternative locus ID - - - 0.000008642 52.0
TH2_k127_8435233_0 ankyrin repeat protein K21440 - - 0.00000000000000000000000000000000147 141.0
TH2_k127_8437298_0 - - - - 0.000000000000000001901 86.0
TH2_k127_8437298_2 COG NOG15344 non supervised orthologous group - - - 0.000002064 51.0
TH2_k127_8479199_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.827e-233 732.0
TH2_k127_8479199_1 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 608.0
TH2_k127_8479199_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 521.0
TH2_k127_8479199_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 519.0
TH2_k127_8479199_4 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007435 520.0
TH2_k127_8479199_5 ThiS family K03636 - - 0.0000000000000000000000000000000001216 134.0
TH2_k127_8479199_6 NIL - - - 0.00000000000000000000000001383 110.0
TH2_k127_8479199_7 PFAM Nitroreductase - - - 0.000007112 48.0
TH2_k127_8487101_0 3-beta hydroxysteroid dehydrogenase/isomerase family K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 451.0
TH2_k127_8557049_0 PFAM Archaeal ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 419.0
TH2_k127_8557049_1 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 323.0
TH2_k127_8557049_2 Transposase - - - 0.0000000000000000000000000000000000006837 147.0
TH2_k127_8557049_3 tyrosine recombinase XerC K04763 - - 0.0000000000000009759 89.0
TH2_k127_8557049_4 PFAM Integrase catalytic region - - - 0.00000000000001749 75.0
TH2_k127_8557049_5 - - - - 0.000000000004912 77.0
TH2_k127_8679005_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1915.0
TH2_k127_8679005_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000002679 229.0
TH2_k127_8679005_2 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000001163 214.0
TH2_k127_8679005_3 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000002787 192.0
TH2_k127_8679005_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000002834 112.0
TH2_k127_8679005_5 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000003452 75.0
TH2_k127_879590_0 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 361.0
TH2_k127_879590_1 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 295.0
TH2_k127_8806158_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.433e-203 639.0
TH2_k127_8806158_1 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 423.0
TH2_k127_8806158_2 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000007623 241.0
TH2_k127_8806158_3 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005514 222.0
TH2_k127_8806158_4 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000002063 198.0
TH2_k127_8806158_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000001976 105.0
TH2_k127_90453_0 MULE transposase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 301.0
TH2_k127_969948_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 304.0
TH2_k127_969948_1 Protein of unknown function (DUF3124) - - - 0.00001591 47.0