GWM

Global Wetland Microbiome Database

Overview

Taxonomy
ID	MAG03907
Name	TH2_bin.36
Sample	SMP0101 120.170431.3307
Kingdom	Bacteria
Phylum	Chloroflexota
Class	Anaerolineae
Order	Anaerolineales
Family	Villigracilaceae
Genus	Defluviilinea
Species
Assembly information
Completeness (%)	92.27
Contamination (%)	7.44
GC content (%)	54.0
N50 (bp)	67,665
Genome size (bp)	4,325,889

Location

Module

Module ID	Module name	Total genes	Total steps	Contain genes	Contain steps	Percentage of genes	Percentage of steps

Genes3709

Gene name	Description	KEGG	GOs	EC	E-value	Score
TH2_k127_1009316_0	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	K00611,K09065,K13252	-	2.1.3.3,2.1.3.6,2.1.3.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722	541.0
TH2_k127_1009316_1	Porphyromonas-type peptidyl-arginine deiminase	K10536	-	3.5.3.12	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647	521.0
TH2_k127_1009316_10	sequence-specific DNA binding	-	-	-	0.00000000000000000000000000000000006478	139.0
TH2_k127_1009316_11	ABC transporter substrate-binding protein PnrA-like	K02058,K07335	-	-	0.0000000000000000013	91.0
TH2_k127_1009316_12	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	K00609	-	2.1.3.2	0.0000000000000001194	80.0
TH2_k127_1009316_13	Domain of unknown function (DUF3473)	-	-	-	0.000002521	58.0
TH2_k127_1009316_14	acetyltransferase	-	-	-	0.000124	51.0
TH2_k127_1009316_2	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	K09065	-	2.1.3.9	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529	517.0
TH2_k127_1009316_4	Amino acid kinase family	K00926	-	2.7.2.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047	460.0
TH2_k127_1009316_6	Amino acid permease	K20265	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107	445.0
TH2_k127_1009316_7	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	K00611,K09065,K13252	-	2.1.3.3,2.1.3.6,2.1.3.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748	368.0
TH2_k127_1009316_8	TIGRFAM FemAB-related protein, PEP-CTERM	-	-	-	0.000000000000000000000000000000000000000000000003191	186.0
TH2_k127_1009316_9	NUDIX domain	-	-	-	0.000000000000000000000000000000000000000000007061	169.0
TH2_k127_1022760_0	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	0.0000000000000000000000000000000000002878	149.0
TH2_k127_1022760_1	DDE superfamily endonuclease	-	-	-	0.0000000000000000000000000001049	118.0
TH2_k127_1022760_2	DDE superfamily endonuclease	-	-	-	0.00000000000003794	74.0
TH2_k127_1022760_3	ThiF family	-	-	-	0.000000002453	63.0
TH2_k127_111542_0	NTF2-like N-terminal transpeptidase domain	K05515	-	3.4.16.4	5.747e-202	653.0
TH2_k127_111542_1	Catalyzes the synthesis of GMP from XMP	K01951	-	6.3.5.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974	576.0
TH2_k127_111542_10	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	K01790	-	5.1.3.13	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003232	276.0
TH2_k127_111542_11	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	K03816	-	2.4.2.22	0.000000000000000000000000000000000000000000000000000000000000000000000000000008698	269.0
TH2_k127_111542_12	SMART protein phosphatase 2C domain protein	K20074	-	3.1.3.16	0.00000000000000000000000000000000000000000000000000000000000000000000005781	253.0
TH2_k127_111542_13	PFAM Maf family protein	K06287	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000007961	246.0
TH2_k127_111542_14	Transposase DDE domain	-	-	-	0.0000000000000000000000000000000000000000000000000004413	194.0
TH2_k127_111542_15	Domain of unknown function (DUF4349)	-	-	-	0.0000000000000000000000000000000000000000000000000006656	198.0
TH2_k127_111542_16	Cupin 2, conserved barrel domain protein	-	-	-	0.0000000000000000000000000000000000000001493	154.0
TH2_k127_111542_17	-	-	-	-	0.000000000000000000000000000000000000001795	160.0
TH2_k127_111542_18	Transposase DDE domain	-	-	-	0.000000000000000000000000000000004145	130.0
TH2_k127_111542_19	SPTR A9B8L4 Integrase catalytic region	-	-	-	0.000000000000000000000000002813	117.0
TH2_k127_111542_2	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	K13038	-	4.1.1.36,6.3.2.5	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122	469.0
TH2_k127_111542_20	SPTR A9B8L4 Integrase catalytic region	-	-	-	0.00000000000000000000000005867	109.0
TH2_k127_111542_21	Uncharacterized conserved protein (DUF2277)	-	-	-	0.0000000000000000001845	90.0
TH2_k127_111542_22	pathogenesis	-	-	-	0.000000000232	74.0
TH2_k127_111542_23	SPTR A9B8L4 Integrase catalytic region	-	-	-	0.00000002927	60.0
TH2_k127_111542_24	PFAM histidine triad (HIT) protein	K02503	-	-	0.000006962	53.0
TH2_k127_111542_3	glycosyl transferase family 2	K07011,K20444	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544	457.0
TH2_k127_111542_4	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	K06949	-	3.1.3.100	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785	369.0
TH2_k127_111542_5	histone H2A K63-linked ubiquitination	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124	342.0
TH2_k127_111542_6	Specifically methylates the N7 position of a guanine in 16S rRNA	K03501	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437	321.0
TH2_k127_111542_7	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	K00067	-	1.1.1.133	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133	316.0
TH2_k127_111542_8	DNA polymerase III, delta prime subunit	K02341	-	2.7.7.7	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262	299.0
TH2_k127_111542_9	PFAM metallophosphoesterase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001131	282.0
TH2_k127_1117000_0	Methionine synthase B12-binding module cap domain protein	K00548,K15023	-	2.1.1.13,2.1.1.258	0.0	1647.0
TH2_k127_1117000_1	Homocysteine S-methyltransferase	K00297,K00547	-	1.5.1.20,2.1.1.10	5.742e-275	857.0
TH2_k127_1117000_10	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	K03525	-	2.7.1.33	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963	372.0
TH2_k127_1117000_11	PFAM Major Facilitator Superfamily	K08223	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903	368.0
TH2_k127_1117000_12	transmembrane transport	K02025,K15771	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569	317.0
TH2_k127_1117000_13	PBP superfamily domain	K05772	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436	301.0
TH2_k127_1117000_14	Leucine carboxyl methyltransferase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000001211	280.0
TH2_k127_1117000_15	Binding-protein-dependent transport system inner membrane component	K05773	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000006625	274.0
TH2_k127_1117000_16	PFAM ATP-binding region, ATPase domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000001555	290.0
TH2_k127_1117000_17	Vacuole effluxer Atg22 like	K06902	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000005922	276.0
TH2_k127_1117000_18	metal-dependent phosphohydrolase, HD sub domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000007426	271.0
TH2_k127_1117000_19	PFAM aminoglycoside phosphotransferase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000008349	255.0
TH2_k127_1117000_2	Stage II sporulation E family protein	-	-	-	9.341e-223	729.0
TH2_k127_1117000_20	Nodulation protein S (NodS)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000002057	250.0
TH2_k127_1117000_21	beta-lactamase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000001356	256.0
TH2_k127_1117000_22	glycerophosphodiester transmembrane transport	K02026	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000002183	248.0
TH2_k127_1117000_23	Binding-protein-dependent transport system inner membrane component	K02018	-	-	0.0000000000000000000000000000000000000000000000000000000000000000002076	239.0
TH2_k127_1117000_24	Bacterial extracellular solute-binding protein	K02020	-	-	0.0000000000000000000000000000000000000000000000000000000000000000009922	236.0
TH2_k127_1117000_25	ABC transporter	K02017,K06857	-	3.6.3.29,3.6.3.55	0.00000000000000000000000000000000000000000000000000000000000002567	222.0
TH2_k127_1117000_26	Domain of unknown function DUF11	-	-	-	0.000000000000000000000000000000000000000000000000000000007419	218.0
TH2_k127_1117000_27	cheY-homologous receiver domain	-	-	-	0.00000000000000000000000000000000000000000000000000000001157	201.0
TH2_k127_1117000_28	Polysaccharide deacetylase	-	-	-	0.00000000000000000000000000000000000000000000000000001274	200.0
TH2_k127_1117000_29	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	K07560	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	0.00000000000000000000000000000000000000000000000000005535	190.0
TH2_k127_1117000_3	Peptidase M16 domain protein	K07263	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801	557.0
TH2_k127_1117000_30	BAAT / Acyl-CoA thioester hydrolase C terminal	K06889	-	-	0.00000000000000000000000000000000000000000000000000007008	196.0
TH2_k127_1117000_31	MoeA C-terminal region (domain IV)	K03750,K07219	-	2.10.1.1	0.0000000000000000000000000000000000000000000000001316	191.0
TH2_k127_1117000_32	methyltransferase	-	-	-	0.000000000000000000000000000000000000000000002237	171.0
TH2_k127_1117000_33	dihydroorotate dehydrogenase activity	K17828	-	1.3.1.14	0.00000000000000000000000000000000000000000000988	171.0
TH2_k127_1117000_34	-	-	-	-	0.0000000000000000000000000000000000000000003988	168.0
TH2_k127_1117000_35	PFAM Beta-lactamase	K18988	-	3.4.16.4	0.0000000000000000000000000000000000000000009613	165.0
TH2_k127_1117000_36	PFAM Sulfate transporter antisigma-factor antagonist STAS	K04749	-	-	0.00000000000000000000000000000000002258	138.0
TH2_k127_1117000_37	F420H(2)-dependent quinone reductase	-	-	-	0.0000000000000000000000000000000001033	138.0
TH2_k127_1117000_38	PFAM Beta-lactamase	K18988	-	3.4.16.4	0.00000000000000000000000000000001338	136.0
TH2_k127_1117000_39	sigma factor antagonist activity	K04757,K17752	-	2.7.11.1	0.0000000000000000000000000000002268	128.0
TH2_k127_1117000_4	Tryptophanyl-tRNA synthetase	K01867	-	6.1.1.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347	518.0
TH2_k127_1117000_40	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	0.000000000000000000000000000001544	139.0
TH2_k127_1117000_41	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	K00997	-	2.7.8.7	0.000000000000000000000000000007551	122.0
TH2_k127_1117000_42	PFAM phospholipid glycerol acyltransferase	K00655	-	2.3.1.51	0.000000000000000000000006853	111.0
TH2_k127_1117000_43	-	K01992	-	-	0.00000000000000000000002475	110.0
TH2_k127_1117000_44	Phosphotransferase enzyme family	K17910	-	2.7.1.190	0.0000000000000000000004559	107.0
TH2_k127_1117000_45	Regulatory protein, FmdB family	-	-	-	0.00000000000000000002319	93.0
TH2_k127_1117000_46	TOBE domain	-	-	-	0.00000000000000000003645	91.0
TH2_k127_1117000_48	CAAX protease self-immunity	-	-	-	0.000000000000002182	85.0
TH2_k127_1117000_49	CAAX protease self-immunity	K07052	-	-	0.00000000000000374	84.0
TH2_k127_1117000_5	PFAM extracellular solute-binding protein family 1	K02027	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469	508.0
TH2_k127_1117000_50	Rdx family	K07401	-	-	0.00000000000000718	76.0
TH2_k127_1117000_51	Uncharacterized protein conserved in bacteria (DUF2314)	-	-	-	0.000000000001608	74.0
TH2_k127_1117000_52	CAAX protease self-immunity	K07052	-	-	0.000006086	52.0
TH2_k127_1117000_53	ATPase family associated with various cellular activities (AAA)	-	-	-	0.00009875	53.0
TH2_k127_1117000_6	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	K00528	-	1.18.1.2,1.19.1.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667	477.0
TH2_k127_1117000_7	Insulinase (Peptidase family M16)	K07263	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645	463.0
TH2_k127_1117000_8	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928	400.0
TH2_k127_1117000_9	ABC-type multidrug transport system ATPase component	K01990	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016	373.0
TH2_k127_1173883_0	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	K03701	-	-	0.0	1458.0
TH2_k127_1173883_1	malic protein domain protein	K00027,K00029	-	1.1.1.38,1.1.1.40	2.769e-300	938.0
TH2_k127_1173883_10	Molecular chaperone. Has ATPase activity	K04079	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138	618.0
TH2_k127_1173883_11	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	K03979	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008408	568.0
TH2_k127_1173883_12	PFAM Radical SAM domain protein	K22227	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658	505.0
TH2_k127_1173883_13	radical SAM	K06871	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221	486.0
TH2_k127_1173883_15	PFAM cytoplasmic peptidoglycan synthetase domain protein	K11754	-	6.3.2.12,6.3.2.17	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293	464.0
TH2_k127_1173883_16	Serine threonine protein kinase	K08884	-	2.7.11.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352	448.0
TH2_k127_1173883_17	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	K03980	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019	443.0
TH2_k127_1173883_18	peptidase M24	K01271	-	3.4.13.9	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044	389.0
TH2_k127_1173883_19	WD40-like Beta Propeller Repeat	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228	409.0
TH2_k127_1173883_2	TIGRFAM methylmalonyl-CoA mutase, large subunit	K01847,K01848	-	5.4.99.2	1.134e-262	818.0
TH2_k127_1173883_20	Glycosyl transferase, family 2	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428	330.0
TH2_k127_1173883_21	Enoyl-(Acyl carrier protein) reductase	K00059,K00068	-	1.1.1.100,1.1.1.140	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942	326.0
TH2_k127_1173883_22	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	K00077	-	1.1.1.169	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372	326.0
TH2_k127_1173883_23	radical SAM domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001686	287.0
TH2_k127_1173883_24	lipid binding	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000006331	278.0
TH2_k127_1173883_25	oxidoreductase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000006625	276.0
TH2_k127_1173883_26	Serine aminopeptidase, S33	K03928	-	3.1.1.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000001929	271.0
TH2_k127_1173883_27	Major facilitator Superfamily	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000001864	271.0
TH2_k127_1173883_28	histone H2A K63-linked ubiquitination	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000002098	262.0
TH2_k127_1173883_29	PFAM Glycerophosphoryl diester phosphodiesterase	K01126	-	3.1.4.46	0.0000000000000000000000000000000000000000000000000000000000000000000000000005677	262.0
TH2_k127_1173883_3	Glycosyl hydrolase family 3 N terminal domain	K01207	-	3.2.1.52	5.622e-251	803.0
TH2_k127_1173883_30	Methyladenine glycosylase	K01246	-	3.2.2.20	0.000000000000000000000000000000000000000000000000000000000000000000000001042	248.0
TH2_k127_1173883_31	Major facilitator superfamily	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000007257	253.0
TH2_k127_1173883_32	TIGRFAM RNA polymerase sigma factor, sigma-70 family	K03088	-	-	0.000000000000000000000000000000000000000000000000000000000000000000002411	239.0
TH2_k127_1173883_33	SMART helix-turn-helix domain protein	K15539	-	-	0.0000000000000000000000000000000000000000000000000000000000008469	231.0
TH2_k127_1173883_34	peptidyl-tyrosine sulfation	-	-	-	0.000000000000000000000000000000000000000000000000000000000003928	222.0
TH2_k127_1173883_35	Type II/IV secretion system protein	K02283,K20527	-	-	0.000000000000000000000000000000000000000000000000000000000522	214.0
TH2_k127_1173883_36	Belongs to the peptidase S26 family	K03100	-	3.4.21.89	0.0000000000000000000000000000000000000000000000000000000912	201.0
TH2_k127_1173883_37	CYTH domain	-	-	-	0.0000000000000000000000000000000000000000000000000000001783	199.0
TH2_k127_1173883_38	FtsZ-dependent cytokinesis	-	-	-	0.0000000000000000000000000000000000000000000000000000002026	200.0
TH2_k127_1173883_39	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	K01338	-	3.4.21.53	0.000000000000000000000000000000000000000000000000000001646	197.0
TH2_k127_1173883_4	Arginyl-tRNA synthetase	K01887	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	7.81e-250	783.0
TH2_k127_1173883_40	Binds to the 23S rRNA	K02939	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.00000000000000000000000000000000000000000000000000002912	192.0
TH2_k127_1173883_41	PFAM HI0933-like protein	K07007	-	-	0.0000000000000000000000000000000000000000000000008973	178.0
TH2_k127_1173883_42	-	-	-	-	0.000000000000000000000000000000000000000000000001965	190.0
TH2_k127_1173883_43	-	-	-	-	0.000000000000000000000000000000000000000000000002532	189.0
TH2_k127_1173883_44	NACHT nucleoside triphosphatase	K12132	-	2.7.11.1	0.000000000000000000000000000000000000000000000009778	194.0
TH2_k127_1173883_45	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	0.0000000000000000000000000000000000000000000000109	181.0
TH2_k127_1173883_46	transcription factor binding	-	-	-	0.0000000000000000000000000000000000000000002389	162.0
TH2_k127_1173883_47	-	-	-	-	0.0000000000000000000000000000000000000000004701	160.0
TH2_k127_1173883_48	Metallo-beta-lactamase superfamily	-	-	-	0.00000000000000000000000000000000000000001492	162.0
TH2_k127_1173883_49	-	-	-	-	0.0000000000000000000000000000000000000000228	168.0
TH2_k127_1173883_5	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	1.178e-236	738.0
TH2_k127_1173883_50	domain, Protein	-	-	-	0.00000000000000000000000000000000000000003473	169.0
TH2_k127_1173883_51	Uncharacterised protein family UPF0047	-	-	-	0.00000000000000000000000000000000000000005795	155.0
TH2_k127_1173883_52	Dual specificity phosphatase, catalytic domain	-	-	-	0.0000000000000000000000000000000000000000825	158.0
TH2_k127_1173883_53	Modulates RecA activity	K03565	-	-	0.0000000000000000000000000000000000000003352	158.0
TH2_k127_1173883_54	Restriction endonuclease BglII	-	-	-	0.000000000000000000000000000000000000002838	149.0
TH2_k127_1173883_56	domain, Protein	-	-	-	0.0000000000000000000000000000000000003302	164.0
TH2_k127_1173883_57	His Kinase A (phosphoacceptor) domain	-	-	-	0.000000000000000000000000000000000001706	142.0
TH2_k127_1173883_59	Fibronectin type III domain	-	-	-	0.00000000000000000000000000000000002057	158.0
TH2_k127_1173883_6	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	K01338	-	3.4.21.53	5.286e-234	739.0
TH2_k127_1173883_60	DNA-templated transcription, initiation	K03088	-	-	0.000000000000000000000000000000000125	140.0
TH2_k127_1173883_61	CoA binding domain	K06929	-	-	0.0000000000000000000000000000000001323	139.0
TH2_k127_1173883_62	methyltransferase	-	-	-	0.00000000000000000000000000000000158	138.0
TH2_k127_1173883_63	integral membrane protein	-	-	-	0.000000000000000000000000000000007786	136.0
TH2_k127_1173883_66	Transposase, IS605 OrfB family	K07496	-	-	0.0000000000000000000002948	102.0
TH2_k127_1173883_67	Protein of unknown function (DUF503)	K09764	-	-	0.0000000000000000000003862	103.0
TH2_k127_1173883_68	Binds directly to 16S ribosomal RNA	K02968	-	-	0.0000000000000000000005181	98.0
TH2_k127_1173883_7	SMART AAA ATPase	-	-	-	3.992e-218	684.0
TH2_k127_1173883_70	transposase	K07496	-	-	0.0000000000000005472	81.0
TH2_k127_1173883_71	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	0.00000000000003967	83.0
TH2_k127_1173883_72	COG0675 Transposase and inactivated derivatives	K07496	-	-	0.0000000000000585	72.0
TH2_k127_1173883_73	Cysteine-rich secretory protein family	-	-	-	0.0000000000001105	83.0
TH2_k127_1173883_74	-	-	-	-	0.0000000000001243	77.0
TH2_k127_1173883_75	domain, Protein	-	-	-	0.0000000000001261	83.0
TH2_k127_1173883_76	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	0.00000000001523	70.0
TH2_k127_1173883_77	Tetratricopeptide TPR_2 repeat protein	-	-	-	0.00000000002035	78.0
TH2_k127_1173883_78	NlpC/P60 family	K19223,K19224,K21471	-	-	0.0000000009833	70.0
TH2_k127_1173883_79	Transposase, IS605 OrfB family	K07496	-	-	0.000000002296	62.0
TH2_k127_1173883_8	Endoribonuclease that initiates mRNA decay	K18682	-	-	5.094e-216	681.0
TH2_k127_1173883_80	Glycosyl hydrolases family 38 C-terminal domain	K01191	-	3.2.1.24	0.00000000231	70.0
TH2_k127_1173883_81	Cysteine-rich secretory protein family	-	-	-	0.000003395	59.0
TH2_k127_1173883_82	type I site-specific deoxyribonuclease activity	K01153	-	3.1.21.3	0.000003884	52.0
TH2_k127_1173883_83	GHKL domain	K07315	-	3.1.3.3	0.00002315	47.0
TH2_k127_1173883_84	-	-	-	-	0.00006219	47.0
TH2_k127_1173883_85	Pfam:Methyltransf_26	-	-	-	0.00014	47.0
TH2_k127_1173883_86	PFAM ATP-binding region, ATPase domain protein	-	-	-	0.0001746	44.0
TH2_k127_1173883_87	FecR protein	-	-	-	0.000286	52.0
TH2_k127_1173883_88	-	-	-	-	0.000302	48.0
TH2_k127_1173883_89	acetyltransferase	K00670,K03789	-	2.3.1.128,2.3.1.256	0.0007178	45.0
TH2_k127_1173883_9	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	K14441	-	2.8.4.4	7.163e-196	619.0
TH2_k127_1173883_90	EcoEI R protein C-terminal	K01153	-	3.1.21.3	0.0007747	43.0
TH2_k127_1181808_0	Fe-S oxidoreductase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237	485.0
TH2_k127_1182689_0	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	0.0	1208.0
TH2_k127_1182689_1	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	K00850	-	2.7.1.11	2.473e-316	983.0
TH2_k127_1182689_10	PFAM major facilitator superfamily MFS_1	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077	597.0
TH2_k127_1182689_11	PFAM ABC transporter	K02056	-	3.6.3.17	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283	560.0
TH2_k127_1182689_12	Pyridoxal-phosphate dependent enzyme	K01733	-	4.2.3.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015	536.0
TH2_k127_1182689_13	Glutamine synthetase, catalytic domain	K01915	-	6.3.1.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474	520.0
TH2_k127_1182689_14	PFAM Glycosyl transferase family 2	K20534	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003	504.0
TH2_k127_1182689_15	Belongs to the thiolase family	K00626	-	2.3.1.9	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343	499.0
TH2_k127_1182689_16	DNA photolyase domain protein	K01669	-	4.1.99.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012	453.0
TH2_k127_1182689_17	PFAM major facilitator superfamily MFS_1	K08151	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009839	440.0
TH2_k127_1182689_18	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	K03547	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459	438.0
TH2_k127_1182689_19	MatE	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852	398.0
TH2_k127_1182689_2	DEAD DEAH box helicase domain protein	K06877	-	-	2.89e-306	959.0
TH2_k127_1182689_20	COG1063 Threonine dehydrogenase and related Zn-dependent	K00008	-	1.1.1.14	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795	374.0
TH2_k127_1182689_21	Belongs to the peptidase S41A family	K03797	-	3.4.21.102	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883	380.0
TH2_k127_1182689_22	Alpha beta hydrolase fold	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293	374.0
TH2_k127_1182689_23	denitrification pathway	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056	376.0
TH2_k127_1182689_24	PFAM aminotransferase, class I and II	K14155	-	4.4.1.8	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484	368.0
TH2_k127_1182689_25	Peptidase_C39 like family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389	367.0
TH2_k127_1182689_26	PFAM regulatory protein, MerR	K22491	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061	360.0
TH2_k127_1182689_27	Peptidase family S51	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528	350.0
TH2_k127_1182689_28	Tryptophanyl-tRNA synthetase	K01867	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551	331.0
TH2_k127_1182689_29	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142	322.0
TH2_k127_1182689_3	C-terminal, D2-small domain, of ClpB protein	K03696	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	4.324e-297	932.0
TH2_k127_1182689_30	formate dehydrogenase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145	327.0
TH2_k127_1182689_31	PFAM Squalene phytoene synthase	K02291	-	2.5.1.32,2.5.1.99	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103	316.0
TH2_k127_1182689_32	PFAM peptidase S51 dipeptidase E	K13282	-	3.4.15.6	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797	307.0
TH2_k127_1182689_33	acetyltransferase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411	311.0
TH2_k127_1182689_34	AAA domain	K02282	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655	306.0
TH2_k127_1182689_35	lysyltransferase activity	K07027	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000116	291.0
TH2_k127_1182689_36	Cytochrome c3	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000001247	284.0
TH2_k127_1182689_37	PFAM binding-protein-dependent transport systems inner membrane component	K02033	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000003171	282.0
TH2_k127_1182689_38	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000003337	274.0
TH2_k127_1182689_39	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	K07304	-	1.8.4.11	0.00000000000000000000000000000000000000000000000000000000000000000000000000002913	265.0
TH2_k127_1182689_4	Heat shock 70 kDa protein	K04043	-	-	1.857e-294	915.0
TH2_k127_1182689_40	lipid binding	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000004105	267.0
TH2_k127_1182689_41	N-terminal TM domain of oligopeptide transport permease C	K02034	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000002706	267.0
TH2_k127_1182689_42	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	K03734	-	2.7.1.180	0.000000000000000000000000000000000000000000000000000000000000000000000000003612	263.0
TH2_k127_1182689_43	PFAM regulatory protein GntR HTH	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000004951	258.0
TH2_k127_1182689_44	Ferric reductase like transmembrane component	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000001046	258.0
TH2_k127_1182689_45	PFAM Polysulphide reductase, NrfD	K00185	-	-	0.0000000000000000000000000000000000000000000000000000000000000000006148	244.0
TH2_k127_1182689_46	zinc-ribbon domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000003297	231.0
TH2_k127_1182689_47	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	K02035	-	-	0.000000000000000000000000000000000000000000000000000000000000000007929	246.0
TH2_k127_1182689_48	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000885	229.0
TH2_k127_1182689_49	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	K12410	-	-	0.0000000000000000000000000000000000000000000000000000000000000001092	230.0
TH2_k127_1182689_5	Pyridoxal-phosphate dependent enzyme	-	-	-	1.306e-247	771.0
TH2_k127_1182689_50	Response regulator receiver	-	-	-	0.00000000000000000000000000000000000000000000000000000000000005077	221.0
TH2_k127_1182689_51	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	K03550	-	3.6.4.12	0.000000000000000000000000000000000000000000000000000000000001982	214.0
TH2_k127_1182689_52	Lysophospholipase L1 and related esterases	-	-	-	0.000000000000000000000000000000000000000000000000000000000005875	215.0
TH2_k127_1182689_53	Belongs to the LOG family	K06966	-	3.2.2.10	0.00000000000000000000000000000000000000000000000000000000000917	212.0
TH2_k127_1182689_54	PFAM peptidase, membrane zinc metallopeptidase	K06973	-	-	0.000000000000000000000000000000000000000000000000000000001273	209.0
TH2_k127_1182689_55	COG0437 Fe-S-cluster-containing hydrogenase components 1	K00184	-	-	0.000000000000000000000000000000000000000000000000000002918	201.0
TH2_k127_1182689_56	ABC transporter substrate-binding protein PnrA-like	-	-	-	0.0000000000000000000000000000000000000000000000000004015	188.0
TH2_k127_1182689_57	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	K01159	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	0.000000000000000000000000000000000000000000000000001187	186.0
TH2_k127_1182689_58	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	0.000000000000000000000000000000000000000000000000004577	189.0
TH2_k127_1182689_59	PFAM phospholipid glycerol acyltransferase	K00655	-	2.3.1.51	0.00000000000000000000000000000000000000000000000001525	188.0
TH2_k127_1182689_6	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	K06001	-	4.2.1.20	6.262e-232	724.0
TH2_k127_1182689_60	PFAM Cytochrome P450	-	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615	-	0.0000000000000000000000000000000000000000000000001114	181.0
TH2_k127_1182689_61	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	K07025	-	-	0.000000000000000000000000000000000000000000000001133	183.0
TH2_k127_1182689_62	GAF domain	-	-	-	0.00000000000000000000000000000000000000000000000439	187.0
TH2_k127_1182689_63	-	-	-	-	0.00000000000000000000000000000000000000000000001093	176.0
TH2_k127_1182689_64	Acetyltransferase (GNAT) domain	-	-	-	0.00000000000000000000000000000000000000000000007026	175.0
TH2_k127_1182689_65	formate dehydrogenase	-	-	-	0.0000000000000000000000000000000000000000000003506	177.0
TH2_k127_1182689_66	GGDEF domain	K13069	-	2.7.7.65	0.0000000000000000000000000000000000000000000004662	181.0
TH2_k127_1182689_67	PFAM phospholipid glycerol acyltransferase	K00655	-	2.3.1.51	0.000000000000000000000000000000000000000000004171	171.0
TH2_k127_1182689_68	diguanylate cyclase	-	-	-	0.0000000000000000000000000000000000000001407	158.0
TH2_k127_1182689_69	Belongs to the thioredoxin family	K03671	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	0.0000000000000000000000000000000000000006524	154.0
TH2_k127_1182689_7	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	K03572	-	-	2.217e-212	675.0
TH2_k127_1182689_70	Histidine kinase	-	-	-	0.0000000000000000000000000000000000003168	158.0
TH2_k127_1182689_71	Flavin containing amine oxidoreductase	-	-	-	0.000000000000000000000000001303	118.0
TH2_k127_1182689_72	PFAM Cytochrome P450	-	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615	-	0.00000000000000000000001696	105.0
TH2_k127_1182689_73	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	0.0000000000000000000004796	101.0
TH2_k127_1182689_74	PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding	K07006	-	-	0.00000000000000000001395	95.0
TH2_k127_1182689_75	Protein of unknown function (DUF3298)	-	-	-	0.00000000000000000006675	100.0
TH2_k127_1182689_76	TIGRFAM lycopene cyclase domain	K22502	-	5.5.1.19	0.00000000000000002505	86.0
TH2_k127_1182689_77	Protein conserved in bacteria	-	-	-	0.000000000000004525	83.0
TH2_k127_1182689_78	cobalamin binding	-	-	-	0.00000000000005641	71.0
TH2_k127_1182689_79	ferrous iron binding	K06990,K15755	-	-	0.000000000006926	68.0
TH2_k127_1182689_8	Amidohydrolase family	K01464,K01466	-	3.5.2.2,3.5.2.5	1.514e-208	657.0
TH2_k127_1182689_80	Cytochrome c554 and c-prime	-	-	-	0.0000000001214	72.0
TH2_k127_1182689_81	acyl-CoA thioester hydrolase, YbgC YbaW family	K07107	-	-	0.00000007449	60.0
TH2_k127_1182689_82	permease	K03548	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	0.000000447	62.0
TH2_k127_1182689_83	Sensory box protein response regulator	-	-	-	0.0000006982	56.0
TH2_k127_1182689_84	Psort location CytoplasmicMembrane, score	-	-	-	0.000003911	60.0
TH2_k127_1182689_85	-	-	-	-	0.000006479	57.0
TH2_k127_1182689_86	COG0823 Periplasmic component of the Tol biopolymer transport system	-	-	-	0.00002793	57.0
TH2_k127_1182689_87	Integron-associated effector binding protein	-	-	-	0.00006689	49.0
TH2_k127_1182689_88	B-1 B cell differentiation	-	-	-	0.0001322	50.0
TH2_k127_1182689_89	FIST_C	-	-	-	0.0002554	50.0
TH2_k127_1182689_9	cobalamin binding	-	-	-	1.82e-196	617.0
TH2_k127_1225294_0	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000007058	224.0
TH2_k127_1225294_1	VIT family	-	-	-	0.00000000000000000000000000000000000000000002011	169.0
TH2_k127_1262704_0	Coenzyme A transferase	-	-	-	0.000000000000000000000000000000000000000000000000000000002574	209.0
TH2_k127_1262704_1	Coenzyme A transferase	K01039	-	2.8.3.12	0.00000000000000000000000000000000000000000000593	171.0
TH2_k127_128150_0	Sulfatase	K01130	-	3.1.6.1	3.077e-229	717.0
TH2_k127_128150_1	COG0659 Sulfate permease and related transporters (MFS superfamily	K03321	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616	404.0
TH2_k127_1298697_0	PFAM aldehyde ferredoxin oxidoreductase	K03738	-	1.2.7.5	1.201e-309	958.0
TH2_k127_1298697_1	PFAM glycosyl transferase, family 35	K00688	-	2.4.1.1	2.089e-306	953.0
TH2_k127_1298697_10	Iron-sulfur cluster-binding domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035	572.0
TH2_k127_1298697_11	Pyruvate:ferredoxin oxidoreductase core domain II	K00174	-	1.2.7.11,1.2.7.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889	556.0
TH2_k127_1298697_12	DEAD DEAH box helicase domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964	472.0
TH2_k127_1298697_13	NAD(P)H-binding	K01784	-	5.1.3.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228	463.0
TH2_k127_1298697_14	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323	454.0
TH2_k127_1298697_15	peptidase M29 aminopeptidase II	K19689	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615	440.0
TH2_k127_1298697_16	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	K00175	-	1.2.7.11,1.2.7.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768	422.0
TH2_k127_1298697_17	PFAM ribonucleotide reductase	K00526	-	1.17.4.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875	384.0
TH2_k127_1298697_18	Psort location CytoplasmicMembrane, score	K02006,K16786,K16787	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325	375.0
TH2_k127_1298697_19	Domain of unknown function (DUF3390)	K18929	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607	389.0
TH2_k127_1298697_2	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	2.516e-272	856.0
TH2_k127_1298697_20	ATPases associated with a variety of cellular activities	K16787	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938	362.0
TH2_k127_1298697_21	4Fe-4S dicluster domain	K00184	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503	344.0
TH2_k127_1298697_22	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525	329.0
TH2_k127_1298697_23	PFAM peptidase M48 Ste24p	K06013	-	3.4.24.84	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102	326.0
TH2_k127_1298697_24	Enoyl- acyl-carrier-protein reductase NADH	K00208	-	1.3.1.10,1.3.1.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583	312.0
TH2_k127_1298697_25	glycosyl transferase group 1	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341	302.0
TH2_k127_1298697_26	Integral membrane protein DUF92	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000896	292.0
TH2_k127_1298697_27	rRNA (adenine-N6,N6-)-dimethyltransferase activity	K00561,K02528	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182,2.1.1.184	0.000000000000000000000000000000000000000000000000000000000000000000000000000000001486	281.0
TH2_k127_1298697_28	Cysteine-rich domain	K18928	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000002746	263.0
TH2_k127_1298697_29	pfkB family carbohydrate kinase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000008465	263.0
TH2_k127_1298697_3	PFAM UvrD REP helicase	-	-	-	6.51e-265	832.0
TH2_k127_1298697_30	Pyruvate ferredoxin/flavodoxin oxidoreductase	K00172,K00177	-	1.2.7.1,1.2.7.3	0.00000000000000000000000000000000000000000000000000000000000000000000000003397	253.0
TH2_k127_1298697_31	Amidohydrolase family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000001232	253.0
TH2_k127_1298697_32	BtpA family	K06971	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000004648	253.0
TH2_k127_1298697_33	Caulimovirus viroplasmin	K03469,K06993	-	3.1.26.4	0.000000000000000000000000000000000000000000000000000000000000000000109	235.0
TH2_k127_1298697_34	methyltransferase	K13311,K13326,K21335	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983	2.1.1.234	0.0000000000000000000000000000000000000000000000000000000000000000006915	235.0
TH2_k127_1298697_35	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	K01881	-	6.1.1.15	0.0000000000000000000000000000000000000000000000000000000000000000009352	247.0
TH2_k127_1298697_37	aldo keto reductase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000002598	229.0
TH2_k127_1298697_38	Cytochrome c7 and related cytochrome c	-	-	-	0.00000000000000000000000000000000000000000000000000000000000005199	218.0
TH2_k127_1298697_39	Belongs to the DNA glycosylase MPG family	K03652	-	3.2.2.21	0.0000000000000000000000000000000000000000000000000000000000002161	217.0
TH2_k127_1298697_4	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	3.098e-256	800.0
TH2_k127_1298697_40	Isochorismatase family	-	-	-	0.000000000000000000000000000000000000000000000000000000001191	205.0
TH2_k127_1298697_41	Psort location CytoplasmicMembrane, score	K16923	-	-	0.00000000000000000000000000000000000000000000000000001076	196.0
TH2_k127_1298697_43	Cobalt transport protein	K16785	-	-	0.000000000000000000000000000000000000000000000000001857	192.0
TH2_k127_1298697_44	PFAM GCN5-related N-acetyltransferase	-	-	-	0.00000000000000000000000000000000000000000000000000253	194.0
TH2_k127_1298697_46	synthase	K01737	-	4.1.2.50,4.2.3.12	0.0000000000000000000000000000000000000000000000004982	178.0
TH2_k127_1298697_47	PFAM phospholipid glycerol acyltransferase	-	-	-	0.0000000000000000000000000000000000000000000000008698	188.0
TH2_k127_1298697_48	Polymer-forming cytoskeletal	-	-	-	0.00000000000000000000000000000000000000000000003388	174.0
TH2_k127_1298697_49	exo-alpha-(2->6)-sialidase activity	K01186	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	0.00000000000000000000000000000000000000000001174	177.0
TH2_k127_1298697_5	AAA domain	-	-	-	1.504e-238	751.0
TH2_k127_1298697_50	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	0.0000000000000000000000000000000000000000000138	168.0
TH2_k127_1298697_51	Belongs to the Nudix hydrolase family	-	-	-	0.00000000000000000000000000000000000000001323	159.0
TH2_k127_1298697_52	PFAM NUDIX hydrolase	-	-	-	0.000000000000000000000000000000000001226	144.0
TH2_k127_1298697_53	Protein of unknown function (DUF3341)	-	-	-	0.00000000000000000000000000000000001854	141.0
TH2_k127_1298697_54	Belongs to the Nudix hydrolase family	-	-	-	0.000000000000000000000000000000001664	134.0
TH2_k127_1298697_55	Lysylphosphatidylglycerol synthase TM region	K07027	-	-	0.0000000000000000000000000000001869	136.0
TH2_k127_1298697_56	Psort location CytoplasmicMembrane, score	-	-	-	0.000000000000000000000000000003374	137.0
TH2_k127_1298697_57	Domain of unknown function (DUF4349)	-	-	-	0.00000000000000000000000000001573	131.0
TH2_k127_1298697_58	TIGRFAM MoaD family protein	K03636	-	-	0.0000000000000000000000000004019	117.0
TH2_k127_1298697_59	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	K00176	-	1.2.7.3	0.0000000000000000000000000006408	114.0
TH2_k127_1298697_6	Molydopterin dinucleotide binding domain	-	-	-	3.769e-232	740.0
TH2_k127_1298697_60	Cold shock	K03704	-	-	0.000000000000000000000000001536	113.0
TH2_k127_1298697_61	PFAM RNP-1 like RNA-binding protein	-	-	-	0.0000000000000000000002755	99.0
TH2_k127_1298697_62	Transcriptional regulatory protein, C terminal	-	-	-	0.00000000000000000007131	102.0
TH2_k127_1298697_63	Transcriptional regulator PadR-like family	-	-	-	0.0000000000000000006149	91.0
TH2_k127_1298697_64	rhodanese-like PpiC domain-containing protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0009719,GO:0009725,GO:0009735,GO:0010033,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	0.000000000000000004563	88.0
TH2_k127_1298697_65	His Kinase A (phosphoacceptor) domain	K07709	-	2.7.13.3	0.000000000000000008092	98.0
TH2_k127_1298697_66	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	K06891	-	-	0.00000000000000004836	85.0
TH2_k127_1298697_67	His Kinase A (phosphoacceptor) domain	-	-	-	0.0000000000000001304	96.0
TH2_k127_1298697_68	PFAM RNA binding S1 domain protein	K02945	-	-	0.000000000002131	81.0
TH2_k127_1298697_69	Sigma-54 factor interaction domain-containing protein	K07713	-	-	0.00000000005419	77.0
TH2_k127_1298697_7	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	K03581	-	3.1.11.5	3.005e-226	725.0
TH2_k127_1298697_70	Protein-tyrosine phosphatase	-	-	-	0.000000000188	74.0
TH2_k127_1298697_71	response to heat	K03668	-	-	0.0000000003906	71.0
TH2_k127_1298697_72	Domain of unknown function (DUF4143)	K07133	-	-	0.000000001415	61.0
TH2_k127_1298697_73	helix_turn_helix multiple antibiotic resistance protein	-	-	-	0.000000005518	64.0
TH2_k127_1298697_75	Diguanylate cyclase	K21022	-	2.7.7.65	0.00000001331	69.0
TH2_k127_1298697_76	PFAM transcription factor CarD	K07736	-	-	0.00000001451	63.0
TH2_k127_1298697_77	transcriptional regulator, winged helix family	K07660	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	0.0000004153	63.0
TH2_k127_1298697_78	Histidine kinase	K00936,K02030	-	2.7.13.3	0.000002479	62.0
TH2_k127_1298697_79	COG1977 Molybdopterin converting factor, small subunit	K03636	-	-	0.00003261	50.0
TH2_k127_1298697_8	PFAM Polysulphide reductase, NrfD	K00185	-	-	1.389e-199	632.0
TH2_k127_1298697_81	Cytochrome C	K08738	-	-	0.000122	53.0
TH2_k127_1298697_82	glyoxalase III activity	-	-	-	0.0001392	50.0
TH2_k127_1298697_9	Belongs to the thiolase family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915	575.0
TH2_k127_1312421_0	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	K03118	-	-	0.000000000000000000000000000000000000000000000000000000006096	211.0
TH2_k127_1312421_1	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	K03625	-	-	0.00000000000000000000000000000000000000000000000000006633	190.0
TH2_k127_1312421_2	protein secretion	K03116,K03117	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	0.00000000001743	69.0
TH2_k127_132182_0	Putative regulatory protein	-	-	-	0.000000000000000151	82.0
TH2_k127_132182_1	Protein of unknown function (DUF1706)	-	-	-	0.0000000000004509	76.0
TH2_k127_1325973_0	WD40 domain protein beta Propeller	K03641	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594	495.0
TH2_k127_1325973_1	heme binding	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031	338.0
TH2_k127_1325973_2	Prokaryotic cytochrome b561	K12262	-	-	0.00000000000000000000000004144	113.0
TH2_k127_1325973_4	PFAM amidohydrolase	K01468	-	3.5.2.7	0.000000003542	58.0
TH2_k127_1338600_0	Belongs to the PEP-utilizing enzyme family	K01006	-	2.7.9.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396	571.0
TH2_k127_1338600_1	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	K01185,K02395,K19223	-	3.2.1.17	0.00000000000000000000000000000005825	134.0
TH2_k127_1350974_0	Bacterial extracellular solute-binding proteins, family 5 Middle	K02035	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172	569.0
TH2_k127_1350974_1	nitrogen compound transport	K02033	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259	441.0
TH2_k127_1410656_0	PFAM Fic DOC family	-	-	-	0.00000000000000000000000000000000000000000000000002595	184.0
TH2_k127_1410656_1	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	0.00000000000000000000000000000000000000000004689	177.0
TH2_k127_1410656_2	response regulator	K02490	-	-	0.000000000006395	70.0
TH2_k127_1418562_0	PFAM Acyl-CoA dehydrogenase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495	541.0
TH2_k127_1418562_1	Likely ribonuclease with RNase H fold.	K06959	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435	541.0
TH2_k127_1418562_2	Spermine/spermidine synthase domain	K00797	-	2.5.1.16	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288	413.0
TH2_k127_1418562_3	TAP-like protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707	364.0
TH2_k127_1418562_4	ABC transporter	K09697	-	3.6.3.7	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609	336.0
TH2_k127_1418562_5	Radical SAM superfamily	K04069	-	1.97.1.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289	327.0
TH2_k127_1418562_6	sodium ABC transporter, permease	K09696	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743	302.0
TH2_k127_1418562_7	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	K00573	-	2.1.1.77	0.00000000000000000000000000000000000000000000000000000000000002293	225.0
TH2_k127_1418562_8	Subtilase family	K08651	-	3.4.21.66	0.00000000000000000000026	108.0
TH2_k127_1432259_0	Glycyl-tRNA synthetase alpha subunit	K14164	-	6.1.1.14	0.0	1062.0
TH2_k127_1432259_1	ATP synthesis coupled electron transport	K00336	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	1.634e-300	942.0
TH2_k127_1432259_10	GMC oxidoreductase	K03333	-	1.1.3.6	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166	574.0
TH2_k127_1432259_11	transmembrane transporter activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435	559.0
TH2_k127_1432259_12	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	K03086	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681	560.0
TH2_k127_1432259_13	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00343	-	1.6.5.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865	511.0
TH2_k127_1432259_14	Belongs to the glycosyl hydrolase 1 family	K01220,K01223,K05350	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657	3.2.1.21,3.2.1.85,3.2.1.86	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058	509.0
TH2_k127_1432259_15	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	K00337	-	1.6.5.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981	430.0
TH2_k127_1432259_16	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591	395.0
TH2_k127_1432259_17	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00331	-	1.6.5.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488	293.0
TH2_k127_1432259_18	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00338,K05580	-	1.6.5.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000239	261.0
TH2_k127_1432259_19	Phosphate acyltransferases	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000004729	276.0
TH2_k127_1432259_2	Class II Aldolase and Adducin N-terminal domain	K01845	-	5.4.3.8	1.079e-219	690.0
TH2_k127_1432259_20	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	K04112	-	1.3.7.8	0.00000000000000000000000000000000000000000000000000000000000000000003626	245.0
TH2_k127_1432259_21	Class II Aldolase and Adducin N-terminal domain	K01845	-	5.4.3.8	0.000000000000000000000000000000000000000000000000000000000000000003133	233.0
TH2_k127_1432259_22	KR domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000001324	233.0
TH2_k127_1432259_23	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	K00334	-	1.6.5.3	0.0000000000000000000000000000000000000000000000000000000000000008701	222.0
TH2_k127_1432259_24	PFAM BadF BadG BcrA BcrD ATPase family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000005831	220.0
TH2_k127_1432259_25	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00332	-	1.6.5.3	0.0000000000000000000000000000000000000000000000000002646	189.0
TH2_k127_1432259_26	Protein of unknown function (DUF3179)	-	-	-	0.0000000000000000000000000000000000000000000000001917	183.0
TH2_k127_1432259_27	Lamin Tail Domain	-	-	-	0.0000000000000000000000000000000000000000000000002775	195.0
TH2_k127_1432259_28	nucleic acid-binding protein contains PIN domain	K07062	-	-	0.00000000000000000000000000000000000000000004277	164.0
TH2_k127_1432259_29	PFAM Formylglycine-generating sulfatase enzyme	K18912	-	1.14.99.50	0.00000000000000000000000000000000000000000922	176.0
TH2_k127_1432259_3	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	K00341	-	1.6.5.3	1.144e-216	694.0
TH2_k127_1432259_30	Belongs to the complex I subunit 6 family	K00339	-	1.6.5.3	0.00000000000000000000000000000000000000008597	156.0
TH2_k127_1432259_31	PFAM Bacterial regulatory proteins, tetR family	-	-	-	0.000000000000000000000000000000000000005717	152.0
TH2_k127_1432259_32	GNAT acetyltransferase	-	-	-	0.0000000000000000000000000000000000002332	151.0
TH2_k127_1432259_33	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00340	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	0.0000000000000000000000000000004601	126.0
TH2_k127_1432259_34	-	-	-	-	0.000000000000000000000000000005435	124.0
TH2_k127_1432259_35	ABC-type multidrug transport system ATPase component	-	-	-	0.000000000000000000000000003115	124.0
TH2_k127_1432259_36	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	K00997	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	2.7.8.7	0.000000000000000000000001056	108.0
TH2_k127_1432259_37	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	0.00000000000000000000001249	117.0
TH2_k127_1432259_38	toxin-antitoxin pair type II binding	-	-	-	0.0000000000000008414	80.0
TH2_k127_1432259_39	protein kinase activity	-	-	-	0.000000000000003551	90.0
TH2_k127_1432259_4	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	K02316	-	-	5.069e-210	670.0
TH2_k127_1432259_40	Protein of unknown function (DUF3179)	-	-	-	0.0000000000005495	71.0
TH2_k127_1432259_41	-	-	-	-	0.00000001645	66.0
TH2_k127_1432259_42	Carrier of the growing fatty acid chain in fatty acid biosynthesis	K02078	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	0.00000003535	57.0
TH2_k127_1432259_43	TIR domain	-	-	-	0.00000004968	57.0
TH2_k127_1432259_44	-	-	-	-	0.0000003761	55.0
TH2_k127_1432259_5	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	K00342	-	1.6.5.3	1.108e-208	662.0
TH2_k127_1432259_6	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	K00335	-	1.6.5.3	3.142e-199	629.0
TH2_k127_1432259_7	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00333	-	1.6.5.3	2.255e-195	616.0
TH2_k127_1432259_8	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	K01897	-	6.2.1.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349	606.0
TH2_k127_1432259_9	FGGY family of carbohydrate kinases, C-terminal domain	K00854	-	2.7.1.17	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447	593.0
TH2_k127_1458291_0	ATPase, P-type (transporting), HAD superfamily, subfamily IC	K17686	-	3.6.3.54	0.0	1102.0
TH2_k127_1458291_1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	K03040	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999	517.0
TH2_k127_1458291_10	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	K00939	-	2.7.4.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000822	278.0
TH2_k127_1458291_11	CO dehydrogenase/acetyl-CoA synthase delta subunit	K00548	-	2.1.1.13	0.000000000000000000000000000000000000000000000000000000000000000000000000000000001568	282.0
TH2_k127_1458291_12	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	K02988	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000001128	266.0
TH2_k127_1458291_13	Belongs to the MenA family. Type 1 subfamily	K02548	-	2.5.1.74	0.000000000000000000000000000000000000000000000000000000000000000000000000000001621	276.0
TH2_k127_1458291_14	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	K02933	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.000000000000000000000000000000000000000000000000000000000000000000000008037	249.0
TH2_k127_1458291_15	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	K06173	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	0.0000000000000000000000000000000000000000000000000000000000000000000006814	244.0
TH2_k127_1458291_16	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	K02994	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.000000000000000000000000000000000000000000000000000000000000007356	218.0
TH2_k127_1458291_17	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	K02948	-	-	0.0000000000000000000000000000000000000000000000000000000000000222	219.0
TH2_k127_1458291_18	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	K02952	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.000000000000000000000000000000000000000000000000000000000000103	214.0
TH2_k127_1458291_19	Methionine synthase B12-binding module cap domain protein	K00548,K14084	-	2.1.1.13	0.0000000000000000000000000000000000000000000000000000000000004467	217.0
TH2_k127_1458291_2	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	K03076	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479	512.0
TH2_k127_1458291_20	Binds to the 23S rRNA	K02876	-	-	0.000000000000000000000000000000000000000000000000000000002386	203.0
TH2_k127_1458291_21	-	-	-	-	0.000000000000000000000000000000000000000000000000000000011	202.0
TH2_k127_1458291_22	PFAM ATP-binding region, ATPase domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000002262	193.0
TH2_k127_1458291_23	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	K02871	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.0000000000000000000000000000000000000000000000000002241	188.0
TH2_k127_1458291_24	Ribosomal protein L17	K02879	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.000000000000000000000000000000000000000000000007447	174.0
TH2_k127_1458291_25	-	-	-	-	0.0000000000000000000000000000000000000000006467	169.0
TH2_k127_1458291_26	Belongs to the universal ribosomal protein uS9 family	K02996	-	-	0.0000000000000000000000000000000000000000007663	165.0
TH2_k127_1458291_27	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	K02881	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	0.00000000000000000000000000000000000000001506	155.0
TH2_k127_1458291_28	Uncharacterized conserved protein (DUF2203)	-	-	-	0.0000000000000000000000000000000000456	138.0
TH2_k127_1458291_29	Metal-sensitive transcriptional repressor	K21600	-	-	0.0000000000000000000000000000004446	125.0
TH2_k127_1458291_3	NAD dependent epimerase dehydratase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008204	402.0
TH2_k127_1458291_30	Acetyltransferase (GNAT) domain	-	-	-	0.000000000000000000000000000002551	129.0
TH2_k127_1458291_31	mercury ion transmembrane transporter activity	K07213	-	-	0.0000000000000000004391	89.0
TH2_k127_1458291_32	mercury ion transmembrane transporter activity	K07213	-	-	0.000000000000000001765	88.0
TH2_k127_1458291_33	Ribosomal protein L30	K02907	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.000000000000005082	76.0
TH2_k127_1458291_34	diguanylate cyclase	-	-	-	0.00000000000004292	75.0
TH2_k127_1458291_35	Belongs to the bacterial ribosomal protein bL36 family	K02919	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.0000000000001816	70.0
TH2_k127_1458291_36	Diguanylate cyclase	-	-	-	0.0000002819	55.0
TH2_k127_1458291_4	Biogenesis protein	K02275,K09792,K17686	-	1.9.3.1,3.6.3.54	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488	383.0
TH2_k127_1458291_5	Belongs to the MenA family. Type 1 subfamily	K02548	-	2.5.1.74	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005	374.0
TH2_k127_1458291_6	TIGRFAM methionine aminopeptidase, type I	K01265	-	3.4.11.18	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291	357.0
TH2_k127_1458291_7	TIGRFAM MazG family protein	K02499	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093	352.0
TH2_k127_1458291_8	TIGRFAM RarD protein, DMT superfamily transporter	K05786	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649	342.0
TH2_k127_1458291_9	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	K02986	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573	309.0
TH2_k127_1501026_0	PFAM GCN5-related N-acetyltransferase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000005313	253.0
TH2_k127_1501026_1	PFAM GCN5-related N-acetyltransferase	-	-	-	0.00000000000000000000000000000000000000000000000000008263	198.0
TH2_k127_1501026_2	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	K07025,K20866	-	3.1.3.10	0.0000000000000000000000000000000000005426	146.0
TH2_k127_1501026_3	PFAM GCN5-related N-acetyltransferase	-	-	-	0.0000000000004585	70.0
TH2_k127_15079_0	Beta-lactamase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000045	279.0
TH2_k127_15079_1	Acetyl xylan esterase (AXE1)	-	-	-	0.00000000000000000000000000000000000000000000000000000009194	213.0
TH2_k127_15079_2	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	0.0000000000002768	75.0
TH2_k127_15079_3	Beta-lactamase	K18988	-	3.4.16.4	0.00004049	56.0
TH2_k127_1539258_0	PHP domain protein	K02347	-	-	6.835e-203	646.0
TH2_k127_1539258_1	Major facilitator superfamily MFS_1	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221	458.0
TH2_k127_1539258_10	GDP-mannose mannosyl hydrolase activity	K03574	-	3.6.1.55	0.00000000000000000000000000000000000000000000000000000002379	200.0
TH2_k127_1539258_11	OsmC-like protein	K09136	-	-	0.000000000000000000000000000000000000000000000006465	186.0
TH2_k127_1539258_12	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	0.00000000000000000000000000000000000000009617	171.0
TH2_k127_1539258_13	FR47-like protein	K18816	-	2.3.1.82	0.00000000000000000000000000000000000516	142.0
TH2_k127_1539258_14	OsmC-like protein	K07397	-	-	0.000000000000000000000000000000009319	131.0
TH2_k127_1539258_15	Putative inner membrane exporter, YdcZ	K09936	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.00000000000000000000000000000001547	131.0
TH2_k127_1539258_16	Putative zinc-finger	-	-	-	0.000000000000000000418	90.0
TH2_k127_1539258_17	Coenzyme A transferase	K01039	-	2.8.3.12	0.00000000000000003288	85.0
TH2_k127_1539258_18	FR47-like protein	-	-	-	0.000000001279	67.0
TH2_k127_1539258_2	Putative esterase	K07214	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418	338.0
TH2_k127_1539258_3	Saccharopine dehydrogenase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032	337.0
TH2_k127_1539258_4	3-oxo-5-alpha-steroid 4-dehydrogenase	K12343	-	1.3.1.22	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000785	274.0
TH2_k127_1539258_5	TIGRFAM glutaredoxin-like domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000343	267.0
TH2_k127_1539258_6	epimerase dehydratase	K00091	-	1.1.1.219	0.00000000000000000000000000000000000000000000000000000000000000000000000000119	265.0
TH2_k127_1539258_7	PFAM sigma-70 region 2 domain protein	K03088	-	-	0.0000000000000000000000000000000000000000000000000000000003021	208.0
TH2_k127_1539258_8	Iron-storage protein	K02217	-	1.16.3.2	0.000000000000000000000000000000000000000000000000000000001008	205.0
TH2_k127_1539258_9	Phosphatidylethanolamine-binding protein	K06910	-	-	0.000000000000000000000000000000000000000000000000000000001263	206.0
TH2_k127_157879_0	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	K01007	-	2.7.9.2	0.0000000000000000000000000000000000000000000000000000000000000000000007962	242.0
TH2_k127_157879_1	hydrolase activity, acting on ester bonds	-	-	-	0.000000000000000000000000000000000000000000000000000000000000002293	228.0
TH2_k127_157879_2	BAAT / Acyl-CoA thioester hydrolase C terminal	K06889	-	-	0.0000000000000000000000000000004762	137.0
TH2_k127_157879_3	BAAT / Acyl-CoA thioester hydrolase C terminal	K06889	-	-	0.00000000000000000000000000000122	137.0
TH2_k127_157879_4	-	-	-	-	0.000000000007916	74.0
TH2_k127_157879_5	PFAM Bacterial regulatory proteins, luxR family	K03556	-	-	0.000000001652	62.0
TH2_k127_157879_6	Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3'	K03556	-	-	0.00003119	51.0
TH2_k127_1587907_0	PFAM extracellular solute-binding protein family 1	K10117,K17315	-	-	4.712e-241	749.0
TH2_k127_1587907_1	Binding-protein-dependent transport system inner membrane component	K17316	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342	479.0
TH2_k127_1587907_2	Binding-protein-dependent transport system inner membrane component	K17317	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094	442.0
TH2_k127_1587907_3	overlaps another CDS with the same product name	K07011	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000324	278.0
TH2_k127_1587907_4	PFAM Glycosyl transferase family 4	K02851	-	2.7.8.33,2.7.8.35	0.0000000000000000000000000000000000000000000000000002346	198.0
TH2_k127_1587907_5	Glycosyltransferase like family 2	K07011	-	-	0.000000000000000000000000000000000000000000002818	174.0
TH2_k127_1587907_6	PFAM MOFRL domain protein	K11529	-	2.7.1.165	0.000000000000000002799	92.0
TH2_k127_1587907_7	PFAM MOFRL domain protein	K11529	-	2.7.1.165	0.000000000000000009738	87.0
TH2_k127_1587907_8	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	K00015	-	1.1.1.26	0.000000000003289	72.0
TH2_k127_170415_0	Belongs to the formate--tetrahydrofolate ligase family	K00288,K01938	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.5.1.5,3.5.4.9,6.3.4.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106	530.0
TH2_k127_170415_1	Belongs to the amidase family	K02433	-	6.3.5.6,6.3.5.7	0.0000000000000000000000000000000000000000000000000000000000000000000000000000004564	271.0
TH2_k127_1736220_0	Coenzyme A transferase	K01040	-	2.8.3.12	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001285	280.0
TH2_k127_1736220_1	Phosphoribosyl synthetase-associated domain	K00948	-	2.7.6.1	0.0000000000000000000000000000000000000000000000000000000000000000000000005272	253.0
TH2_k127_1736220_2	methyltransferase activity	-	-	-	0.0000000000000000000000000005494	121.0
TH2_k127_1736220_3	Acetyltransferase (GNAT) domain	-	-	-	0.000000000000000000002036	101.0
TH2_k127_1748662_0	PFAM GCN5-related N-acetyltransferase	-	-	-	0.00000000000000000000000000000000000000000000004177	181.0
TH2_k127_1748662_1	Acetyltransferase (GNAT) domain	-	-	-	0.0000000000000000000000000000000000000347	149.0
TH2_k127_1748662_2	Acetyltransferase (GNAT) domain	-	-	-	0.00000000000000000000000000000000000005972	150.0
TH2_k127_1748662_3	Acetyltransferase (GNAT) domain	-	-	-	0.00000000000000000000000000000000001676	143.0
TH2_k127_1748662_4	FR47-like protein	-	-	-	0.0000000000000000000000000005622	125.0
TH2_k127_1786125_0	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	K06997	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000006068	272.0
TH2_k127_1786125_1	Belongs to the multicopper oxidase YfiH RL5 family	K05810	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000001875	261.0
TH2_k127_1786125_2	Predicted membrane protein (DUF2085)	-	-	-	0.0000000007086	61.0
TH2_k127_181107_0	Required for chromosome condensation and partitioning	K03529	-	-	0.0	1075.0
TH2_k127_181107_1	DHH family	K07462	-	-	1.695e-195	635.0
TH2_k127_181107_10	Binds together with S18 to 16S ribosomal RNA	K02990	-	-	0.000000000000000000000000001021	116.0
TH2_k127_181107_11	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	K02963	-	-	0.0000000000000000000000003901	107.0
TH2_k127_181107_12	-	-	-	-	0.00001123	56.0
TH2_k127_181107_2	Aminotransferase class-III	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146	522.0
TH2_k127_181107_3	Glycosyl hydrolase family 20, catalytic domain	K12373	-	3.2.1.52	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112	517.0
TH2_k127_181107_4	PFAM type II secretion system protein E	K02283	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246	435.0
TH2_k127_181107_5	Aldo/keto reductase family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683	333.0
TH2_k127_181107_6	Rieske [2Fe-2S] domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485	334.0
TH2_k127_181107_7	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286	313.0
TH2_k127_181107_8	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	K03685	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000007577	264.0
TH2_k127_181107_9	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	K03111	-	-	0.0000000000000000000000000000000000000000000000000000000000000001197	224.0
TH2_k127_1950155_0	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	K00036	-	1.1.1.363,1.1.1.49	9.108e-234	730.0
TH2_k127_1955215_0	PFAM Type II secretion system protein E	K02283	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401	421.0
TH2_k127_1955215_1	Aldo/keto reductase family	-	-	-	0.0000000000000000000000000000000000000000000001533	171.0
TH2_k127_204932_0	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	K03070	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	0.0	1480.0
TH2_k127_204932_1	Radical_SAM C-terminal domain	K07739	-	2.3.1.48	5.119e-244	764.0
TH2_k127_204932_10	PFAM oxidoreductase, molybdopterin binding	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279	349.0
TH2_k127_204932_11	TIGRFAM LAO AO transport system ATPase	K07588	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714	338.0
TH2_k127_204932_12	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	K10563	-	3.2.2.23,4.2.99.18	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895	316.0
TH2_k127_204932_13	-	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395	316.0
TH2_k127_204932_14	Beta-lactamase superfamily domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117	317.0
TH2_k127_204932_15	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	K00858	-	2.7.1.23	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685	312.0
TH2_k127_204932_16	Fumarase C-terminus	K01676,K01678	-	4.2.1.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895	308.0
TH2_k127_204932_17	Heat shock protein DnaJ domain protein	K05516	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764	301.0
TH2_k127_204932_18	GPH family sugar transporter	K03292	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299	308.0
TH2_k127_204932_19	Acetyltransferase (GNAT) domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004196	293.0
TH2_k127_204932_2	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	K01681	-	4.2.1.3	1.851e-210	664.0
TH2_k127_204932_20	Crp-like helix-turn-helix domain	K10914	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000001014	246.0
TH2_k127_204932_21	PFAM cobalamin B12-binding domain protein	K01849	-	5.4.99.2	0.0000000000000000000000000000000000000000000000000000000000003037	214.0
TH2_k127_204932_22	pseudouridine synthase activity	K06178,K06181,K06183	-	5.4.99.19,5.4.99.20,5.4.99.22	0.0000000000000000000000000000000000000000000000000000000000004241	240.0
TH2_k127_204932_23	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000002918	213.0
TH2_k127_204932_25	methyltransferase activity	K02169	-	2.1.1.197	0.0000000000000000000000000000000000000000000000000000001901	203.0
TH2_k127_204932_26	Phosphoadenosine phosphosulfate reductase family	K00390	-	1.8.4.10,1.8.4.8	0.0000000000000000000000000000000000000000000000000000007816	201.0
TH2_k127_204932_27	lyase activity	-	-	-	0.0000000000000000000000000000000000000000000000001837	188.0
TH2_k127_204932_28	Domain of unknown function DUF83	K07464	-	3.1.12.1	0.0000000000000000000000000000000000000000000000002519	182.0
TH2_k127_204932_29	Involved in initiation control of chromosome replication	-	-	-	0.00000000000000000000000000000000000000000006513	167.0
TH2_k127_204932_3	May be involved in recombinational repair of damaged DNA	K03631	-	-	3.648e-202	644.0
TH2_k127_204932_30	-	-	-	-	0.0000000000000000000000000000000000000000003382	166.0
TH2_k127_204932_31	Lipase (class 3)	-	-	-	0.000000000000000000000000000000000000000534	160.0
TH2_k127_204932_32	Type IV pilus biogenesis stability protein PilW	-	-	-	0.000000000000000000000000000000001908	136.0
TH2_k127_204932_33	-	-	-	-	0.0000000000000000000000000000002026	133.0
TH2_k127_204932_34	transporter	K07240	-	-	0.000000000000000004285	93.0
TH2_k127_204932_35	COG2059 Chromate transport protein ChrA	K07240	-	-	0.00000000000000005736	87.0
TH2_k127_204932_37	Belongs to the sigma-70 factor family. ECF subfamily	K03088	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.00000000000001319	81.0
TH2_k127_204932_4	Carbohydrate kinase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205	465.0
TH2_k127_204932_40	PFAM UspA domain protein	-	-	-	0.00000000001487	75.0
TH2_k127_204932_42	Serine aminopeptidase, S33	K09023	-	-	0.0000000004947	70.0
TH2_k127_204932_5	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	K00948	-	2.7.6.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401	441.0
TH2_k127_204932_6	Fumarate hydratase (Fumerase)	K01676,K01677	-	4.2.1.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753	408.0
TH2_k127_204932_7	ADP binding	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728	417.0
TH2_k127_204932_8	PFAM Adenosine AMP deaminase	K01488	-	3.5.4.4	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151	394.0
TH2_k127_204932_9	PFAM peptidase S1 and S6, chymotrypsin Hap	K04771	-	3.4.21.107	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049	389.0
TH2_k127_21501_0	MoeA N-terminal region (domain I and II)	K03750	-	2.10.1.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359	380.0
TH2_k127_21501_2	Vitamin K epoxide reductase	-	-	-	0.000000000007092	71.0
TH2_k127_2305821_0	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	K00077	-	1.1.1.169	0.0000000000000000000000000000000000000000000000000000000001896	214.0
TH2_k127_2305821_1	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	K00606	-	2.1.2.11	0.00000000000000000000000000000000000003228	145.0
TH2_k127_2305821_2	Integral membrane sensor signal transduction histidine kinase	K07680,K07778,K11617,K14988	-	2.7.13.3	0.00000000000000000000000001877	119.0
TH2_k127_2305821_3	-	-	-	-	0.000000000000000000006522	103.0
TH2_k127_2310332_0	ROK family	K00847	-	2.7.1.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775	411.0
TH2_k127_2310332_1	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	K01918	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969	311.0
TH2_k127_2310332_2	alpha beta	K06889	-	-	0.00000000000000000000000000000000000002632	154.0
TH2_k127_2310332_3	Involved in the tonB-independent uptake of proteins	-	-	-	0.00000000000000000000314	108.0
TH2_k127_2310332_4	protein conserved in bacteria	-	-	-	0.00005047	47.0
TH2_k127_2315010_0	AMP-binding enzyme C-terminal domain	K01897	-	6.2.1.3	0.00000000000000000000000000000000000000000000002433	179.0
TH2_k127_2315010_1	DNA-binding transcriptional activator of the SARP family	-	-	-	0.000000000141	66.0
TH2_k127_2336273_0	PFAM aldehyde ferredoxin oxidoreductase	K03738	-	1.2.7.5	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341	606.0
TH2_k127_2336273_1	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	K01903	-	6.2.1.5	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969	570.0
TH2_k127_2336273_10	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008038	302.0
TH2_k127_2336273_11	Alpha/beta hydrolase of unknown function (DUF1100)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004268	290.0
TH2_k127_2336273_12	PFAM ATP-binding region, ATPase domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000001288	291.0
TH2_k127_2336273_13	Amidinotransferase	K01482	-	3.5.3.18	0.00000000000000000000000000000000000000000000000000000000000000000000000000000004844	274.0
TH2_k127_2336273_14	Belongs to the 'phage' integrase family	K04763	-	-	0.0000000000000000000000000000000000000000000000000000000000000000001404	240.0
TH2_k127_2336273_15	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	K02029	-	-	0.0000000000000000000000000000000000000000000000000000000002661	213.0
TH2_k127_2336273_16	cellular response to dsDNA	K07178	-	2.7.11.1	0.0000000000000000000000000000000000000000000000000000000009267	216.0
TH2_k127_2336273_17	Belongs to the bacterial solute-binding protein 3 family	-	-	-	0.00000000000000000000000000000000000000000000000000002918	200.0
TH2_k127_2336273_18	-	-	-	-	0.00000000000000000000000000000000001314	150.0
TH2_k127_2336273_19	SCP-2 sterol transfer family	-	-	-	0.0000000000000000000000006594	110.0
TH2_k127_2336273_2	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237	559.0
TH2_k127_2336273_20	Carrier of the growing fatty acid chain in fatty acid biosynthesis	K02078	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	0.00000000000000000000001202	102.0
TH2_k127_2336273_21	PFAM SNARE associated Golgi protein	-	-	-	0.00000000000000000001531	96.0
TH2_k127_2336273_22	Antibiotic biosynthesis monooxygenase	K11530	-	5.3.1.32	0.0000000000000000004306	91.0
TH2_k127_2336273_23	Domain of unknown function (DUF4160)	-	-	-	0.000000696	55.0
TH2_k127_2336273_3	PFAM ABC transporter transmembrane region	K06147	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037	534.0
TH2_k127_2336273_4	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	K01902	-	6.2.1.5	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159	491.0
TH2_k127_2336273_5	ABC transporter, transmembrane region	K06147,K18890	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217	489.0
TH2_k127_2336273_6	Trimethylamine methyltransferase	K14083	-	2.1.1.250	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141	456.0
TH2_k127_2336273_7	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	K01823	-	5.3.3.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901	438.0
TH2_k127_2336273_8	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	K00606	-	2.1.2.11	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003	299.0
TH2_k127_2336273_9	ABC transporter	K02028	-	3.6.3.21	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001638	290.0
TH2_k127_2433884_0	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877	421.0
TH2_k127_2433884_1	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207	388.0
TH2_k127_2433884_2	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000196	247.0
TH2_k127_2433884_3	Putative FMN-binding domain	K07734	-	-	0.00000000000000000000000000000000000000000001273	167.0
TH2_k127_2433884_4	Helix-turn-helix XRE-family like proteins	K07729	-	-	0.000000000000000000000001578	105.0
TH2_k127_2433884_6	-	-	-	-	0.0000000000000000001478	94.0
TH2_k127_2433884_7	Antibiotic biosynthesis monooxygenase	-	-	-	0.000000000000000001596	89.0
TH2_k127_2435777_0	Belongs to the HMG-CoA reductase family	K00054	-	1.1.1.88	2.025e-198	625.0
TH2_k127_2435777_1	transcriptional regulator	K03556	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029	631.0
TH2_k127_2435777_10	Belongs to the universal ribosomal protein uS2 family	K02967	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593	380.0
TH2_k127_2435777_11	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	K00806	-	2.5.1.31	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102	349.0
TH2_k127_2435777_12	Catalyzes the reversible phosphorylation of UMP to UDP	K09903	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858	340.0
TH2_k127_2435777_13	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	K02838	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000001289	266.0
TH2_k127_2435777_14	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	K02357	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000006136	256.0
TH2_k127_2435777_15	DUF35 OB-fold domain, acyl-CoA-associated	K07068	-	-	0.0000000000000000000000000000000000000000000000000000000000000008235	221.0
TH2_k127_2435777_16	Belongs to the CDS family	K00981	-	2.7.7.41	0.000000000000000000000000000000000000000000000000000000000000004483	228.0
TH2_k127_2435777_17	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	K02851,K13007	-	2.7.8.33,2.7.8.35	0.000000000000000000000000000000000000000000000000000003301	204.0
TH2_k127_2435777_18	DNA-templated transcription, initiation	K03088	-	-	0.00000000000000000000000000000000004955	140.0
TH2_k127_2435777_19	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	0.00000000000000000000008403	104.0
TH2_k127_2435777_2	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	K02313	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381	597.0
TH2_k127_2435777_21	-	-	-	-	0.000000000000006585	78.0
TH2_k127_2435777_22	-	-	-	-	0.0000007301	61.0
TH2_k127_2435777_23	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	0.000009181	51.0
TH2_k127_2435777_3	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059	561.0
TH2_k127_2435777_4	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	K01641	-	2.3.3.10	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792	548.0
TH2_k127_2435777_5	Heparinase II/III N-terminus	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381	520.0
TH2_k127_2435777_6	Glycosyl transferase 4-like domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312	488.0
TH2_k127_2435777_7	PFAM Acetyl xylan esterase	K01060	-	3.1.1.41	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965	483.0
TH2_k127_2435777_8	Belongs to the thiolase family	K00626	-	2.3.1.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182	443.0
TH2_k127_2435777_9	TIGRFAM fructose-1,6-bisphosphatase, class II	K02446	-	3.1.3.11	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369	435.0
TH2_k127_2492614_0	Cache domain	-	-	-	0.00000000000000000000000000000000001101	154.0
TH2_k127_2492614_1	Cys Met metabolism	K01739,K01758	-	2.5.1.48,4.4.1.1	0.00000000000005085	72.0
TH2_k127_260279_0	Belongs to the ompA family	K20276	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056	414.0
TH2_k127_260279_1	Cupin 2, conserved barrel domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179	319.0
TH2_k127_260279_2	Aspartyl/Asparaginyl beta-hydroxylase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000003556	254.0
TH2_k127_260279_3	PFAM Tail Collar domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000001006	228.0
TH2_k127_260279_4	Acetyltransferase (GNAT) family	-	-	-	0.0000000000000000000000000000000000000000001991	164.0
TH2_k127_260279_5	-	-	-	-	0.0000000000000000000000000000000000000000003803	162.0
TH2_k127_260279_6	Polymorphic membrane protein, Chlamydia	-	-	-	0.0000000000000000000000000000000000002878	164.0
TH2_k127_260279_7	CAAX protease self-immunity	-	-	-	0.000000000000000000000000000009714	128.0
TH2_k127_260279_9	-	-	-	-	0.00000001112	60.0
TH2_k127_260926_0	Cytochrome b/b6/petB	K00412,K03888	-	-	0.000000000000000000000000000000000000000000000000000000000000000000005803	241.0
TH2_k127_260926_1	Menaquinol-cytochrome c reductase	K03886	-	-	0.000000000000000000000002513	109.0
TH2_k127_260926_2	Cytochrome b(C-terminal)/b6/petD	K00412	-	-	0.0000000000000000003551	101.0
TH2_k127_260926_3	Cytochrome c	K00406,K03889	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	0.0002234	53.0
TH2_k127_2611774_0	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178	374.0
TH2_k127_2611774_1	transcriptional regulator, LuxR family	-	-	-	0.00001888	50.0
TH2_k127_2629764_0	hydrolase activity, acting on ester bonds	-	-	-	0.000000000000000000000000000000000000000000000000000001069	205.0
TH2_k127_2629764_1	COG1073 Hydrolases of the alpha beta superfamily	K06889	-	-	0.000000000000000000004379	101.0
TH2_k127_2683952_0	Two component regulator propeller	K00936	-	2.7.13.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585	565.0
TH2_k127_2683952_1	Bacterial extracellular solute-binding proteins, family 5 Middle	K02035	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521	557.0
TH2_k127_2683952_2	nitrogen compound transport	K02033	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534	422.0
TH2_k127_2683952_3	Binding-protein-dependent transport system inner membrane component	K02034,K15582	-	-	0.0000000000000000000000000000000000000000000000000000000000000929	222.0
TH2_k127_2699197_0	heavy metal translocating P-type ATPase	K01533,K17686	-	3.6.3.4,3.6.3.54	0.00000000000000000000000000000000000000000000000000000000000000000000000000000006578	269.0
TH2_k127_2699197_1	Multicopper oxidase	K22348	-	1.16.3.3	0.000000000000000000000000000006577	123.0
TH2_k127_279269_0	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	K03701	-	-	9.375e-213	665.0
TH2_k127_279269_1	LysM domain	K02020	-	-	0.0000000000000001934	84.0
TH2_k127_2799879_0	PFAM alpha-2-macroglobulin domain protein	K06894	-	-	0.0	2075.0
TH2_k127_2799879_1	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	1.551e-293	917.0
TH2_k127_2799879_10	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	2.221e-206	651.0
TH2_k127_2799879_11	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	K01885	-	6.1.1.17	1.042e-203	645.0
TH2_k127_2799879_12	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235	587.0
TH2_k127_2799879_13	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723	575.0
TH2_k127_2799879_14	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	K11645	-	4.1.2.13	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622	557.0
TH2_k127_2799879_15	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	K06147	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324	555.0
TH2_k127_2799879_16	TIGRFAM cell shape determining protein, MreB Mrl family	K03569	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266	527.0
TH2_k127_2799879_17	ABC transporter transmembrane region	K06147,K06148	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379	529.0
TH2_k127_2799879_18	PFAM NAD-dependent epimerase dehydratase	K01710,K08678	-	4.1.1.35,4.2.1.46	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791	505.0
TH2_k127_2799879_19	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	K00549	-	2.1.1.14	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803	501.0
TH2_k127_2799879_2	spermidine synthase activity	-	-	-	1.105e-264	833.0
TH2_k127_2799879_20	SMART AAA ATPase	K03405	-	6.6.1.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344	498.0
TH2_k127_2799879_21	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	K00611	-	2.1.3.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253	490.0
TH2_k127_2799879_22	pathogenesis	K21471,K21687	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095	487.0
TH2_k127_2799879_23	PFAM thiamine pyrophosphate protein domain protein TPP-binding	K00175	-	1.2.7.11,1.2.7.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648	462.0
TH2_k127_2799879_24	Synthesizes alpha-1,4-glucan chains using ADP-glucose	K00703	-	2.4.1.21	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649	459.0
TH2_k127_2799879_25	ABC transporter permease	K02025	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514	424.0
TH2_k127_2799879_26	Amidohydrolase family	K06015	-	3.5.1.81	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105	434.0
TH2_k127_2799879_27	Belongs to the pyruvate kinase family	K00873	-	2.7.1.40	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927	428.0
TH2_k127_2799879_28	solute-binding protein	K02027	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942	422.0
TH2_k127_2799879_29	PFAM Uroporphyrinogen decarboxylase (URO-D)	K01599	-	4.1.1.37	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421	418.0
TH2_k127_2799879_3	tRNA synthetases class I (E and Q), anti-codon binding domain	K01886	-	6.1.1.18	5.297e-255	798.0
TH2_k127_2799879_30	Cys/Met metabolism PLP-dependent enzyme	K01739,K01761	-	2.5.1.48,4.4.1.11	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042	421.0
TH2_k127_2799879_31	Nucleotidyl transferase	K00975	-	2.7.7.27	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126	416.0
TH2_k127_2799879_32	lipolytic protein G-D-S-L family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689	408.0
TH2_k127_2799879_33	Belongs to the SEDS family	K05837	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047	393.0
TH2_k127_2799879_34	Aminotransferase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038	379.0
TH2_k127_2799879_35	Belongs to the ParA family	K03609	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072	376.0
TH2_k127_2799879_36	SIS domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523	362.0
TH2_k127_2799879_37	Protein of unknown function (DUF1295)	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913	357.0
TH2_k127_2799879_38	Binding-protein-dependent transport system inner membrane component	K02026	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631	349.0
TH2_k127_2799879_39	Peptidase family M28	K13049	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048	353.0
TH2_k127_2799879_4	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	K00174	-	1.2.7.11,1.2.7.3	2.068e-246	776.0
TH2_k127_2799879_40	ROK family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345	343.0
TH2_k127_2799879_41	Belongs to the pseudouridine synthase RsuA family	K06178,K06181	-	5.4.99.20,5.4.99.22	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418	323.0
TH2_k127_2799879_42	alanine dehydrogenase activity	K00259	GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009653,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030312,GO:0030435,GO:0032502,GO:0036293,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718	323.0
TH2_k127_2799879_43	Beta-lactamase superfamily domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364	317.0
TH2_k127_2799879_44	2-aminoethylphosphonate-pyruvate transaminase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934	310.0
TH2_k127_2799879_45	alpha/beta hydrolase fold	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237	296.0
TH2_k127_2799879_46	purine nucleotide biosynthetic process	K02529	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001109	295.0
TH2_k127_2799879_47	Cytidine monophosphokinase	K00876	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001523	285.0
TH2_k127_2799879_48	Involved in formation and maintenance of cell shape	K03570	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000255	285.0
TH2_k127_2799879_49	Leucyl aminopeptidase (Aminopeptidase T)	K19689	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000002107	283.0
TH2_k127_2799879_5	Beta-galactosidase trimerisation domain	K12308	-	3.2.1.23	1.166e-233	742.0
TH2_k127_2799879_50	PFAM DegV family protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000004388	279.0
TH2_k127_2799879_51	Enoyl-(Acyl carrier protein) reductase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000006084	277.0
TH2_k127_2799879_52	Alpha/beta hydrolase family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000005185	271.0
TH2_k127_2799879_53	Adenosine specific kinase	K09129	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000006477	269.0
TH2_k127_2799879_54	amino acid-binding ACT domain protein	K04767	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000001194	259.0
TH2_k127_2799879_55	Uroporphyrinogen decarboxylase (URO-D)	K01599	-	4.1.1.37	0.0000000000000000000000000000000000000000000000000000000000000000000000002832	261.0
TH2_k127_2799879_56	succinylglutamate desuccinylase aspartoacylase	K07402	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000001446	253.0
TH2_k127_2799879_57	FCD domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000001122	245.0
TH2_k127_2799879_58	Beta-lactamase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000002147	254.0
TH2_k127_2799879_59	Adenylate and Guanylate cyclase catalytic domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000001481	227.0
TH2_k127_2799879_6	PFAM penicillin-binding protein transpeptidase	K05515	-	3.4.16.4	1.372e-219	704.0
TH2_k127_2799879_60	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	K03767,K03768	-	5.2.1.8	0.000000000000000000000000000000000000000000000000000000000000001084	223.0
TH2_k127_2799879_61	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	K17884	-	2.7.8.39	0.0000000000000000000000000000000000000000000000000000000000001674	221.0
TH2_k127_2799879_62	lysyltransferase activity	K07027	-	-	0.000000000000000000000000000000000000000000000000000000000002207	221.0
TH2_k127_2799879_63	Methyltransferase	K08316	-	2.1.1.171	0.000000000000000000000000000000000000000000000000000000000004101	213.0
TH2_k127_2799879_64	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	K01714	-	4.3.3.7	0.0000000000000000000000000000000000000000000000000000000002014	214.0
TH2_k127_2799879_65	Protein of unknown function (DUF3159)	-	-	-	0.0000000000000000000000000000000000000000000000000000000003316	210.0
TH2_k127_2799879_66	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	K06024	-	-	0.0000000000000000000000000000000000000000000000000000000005206	207.0
TH2_k127_2799879_67	KDPG and KHG aldolase	K01625	-	4.1.2.14,4.1.3.42	0.0000000000000000000000000000000000000000000000000000000005349	208.0
TH2_k127_2799879_68	Acetyltransferase (GNAT) domain	K03817	-	-	0.000000000000000000000000000000000000000000000000000000002273	207.0
TH2_k127_2799879_69	membrane	-	-	-	0.000000000000000000000000000000000000000000000000000000002905	210.0
TH2_k127_2799879_7	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	K00819,K00821	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.11,2.6.1.13,2.6.1.17	7.376e-217	677.0
TH2_k127_2799879_70	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	K03610	-	-	0.00000000000000000000000000000000000000000000000000000001482	205.0
TH2_k127_2799879_71	carboxylic ester hydrolase activity	-	-	-	0.000000000000000000000000000000000000000000000000000001133	203.0
TH2_k127_2799879_72	Asparaginase, N-terminal	K01424	-	3.5.1.1	0.000000000000000000000000000000000000000000000000000001346	196.0
TH2_k127_2799879_73	membrane transporter protein	K07090	-	-	0.0000000000000000000000000000000000000000000000000003309	192.0
TH2_k127_2799879_74	alpha/beta hydrolase fold	K00641	-	2.3.1.31	0.00000000000000000000000000000000000000000000000008252	192.0
TH2_k127_2799879_75	Uncharacterised protein, DegV family COG1307	-	-	-	0.000000000000000000000000000000000000000000000002004	183.0
TH2_k127_2799879_76	PFAM thioesterase superfamily protein	-	-	-	0.000000000000000000000000000000000000000000000009698	175.0
TH2_k127_2799879_77	Kdo2-lipid A biosynthetic process	K02517,K20543,K22311	-	2.3.1.241,2.3.1.265	0.0000000000000000000000000000000000000000000003262	178.0
TH2_k127_2799879_78	PFAM SNARE associated Golgi protein	-	-	-	0.0000000000000000000000000000000000000000000005297	175.0
TH2_k127_2799879_79	-	-	-	-	0.000000000000000000000000000000000000000000001161	171.0
TH2_k127_2799879_8	PFAM glycoside hydrolase, family 77	K00705	-	2.4.1.25	7.108e-214	676.0
TH2_k127_2799879_80	GDP-mannose mannosyl hydrolase activity	K01515,K03574,K13669,K19710	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.7.53,3.6.1.13,3.6.1.55	0.000000000000000000000000000000000000000000006226	168.0
TH2_k127_2799879_81	Major facilitator Superfamily	-	-	-	0.00000000000000000000000000000000000000000004162	177.0
TH2_k127_2799879_82	PFAM DinB family protein	-	-	-	0.0000000000000000000000000000000000000000004899	163.0
TH2_k127_2799879_83	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	K07636	-	2.7.13.3	0.00000000000000000000000000000000000000000217	170.0
TH2_k127_2799879_84	GtrA-like protein	-	-	-	0.00000000000000000000000000000000000000664	150.0
TH2_k127_2799879_85	RF-1 domain	K15034	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	0.0000000000000000000000000000000000001615	146.0
TH2_k127_2799879_86	Protein of unknown function (DUF1361)	-	-	-	0.00000000000000000000000000000000001524	144.0
TH2_k127_2799879_87	Protein of unknown function (DUF1475)	-	-	-	0.0000000000000000000000000000000001876	134.0
TH2_k127_2799879_88	Protein of unknown function (DUF1361)	-	-	-	0.000000000000000000000000000000003729	138.0
TH2_k127_2799879_89	Major facilitator Superfamily	-	-	-	0.0000000000000000000000000000004445	139.0
TH2_k127_2799879_9	PFAM peptidase M20	-	-	-	1.129e-213	671.0
TH2_k127_2799879_91	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	0.000000000000000000000000000004071	137.0
TH2_k127_2799879_92	Putative auto-transporter adhesin, head GIN domain	-	-	-	0.0000000000000000000000000005556	125.0
TH2_k127_2799879_93	-	-	-	-	0.00000000000000000000000001681	115.0
TH2_k127_2799879_94	-	-	-	-	0.00000000000000000000000003452	119.0
TH2_k127_2799879_95	Periplasmic binding protein domain	K10439	-	-	0.0000000000000000000000528	102.0
TH2_k127_2799879_96	transcriptional regulator	-	-	-	0.0000000000000000000002171	105.0
TH2_k127_2799879_97	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	K03608	-	-	0.0000000000000000003284	91.0
TH2_k127_2799879_99	-	-	-	-	0.000001224	59.0
TH2_k127_2820426_0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	K03046	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	0.0	2112.0
TH2_k127_2820426_1	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	0.0	1461.0
TH2_k127_2820426_10	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	K01733	-	4.2.3.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208	454.0
TH2_k127_2820426_11	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	K06942	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758	450.0
TH2_k127_2820426_12	lactate metabolic process	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863	383.0
TH2_k127_2820426_13	V-type ATPase 116kDa subunit family	K02123	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631	391.0
TH2_k127_2820426_14	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171	373.0
TH2_k127_2820426_15	heterodisulfide reductase	K03389	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774	330.0
TH2_k127_2820426_16	O-methyltransferase activity	K00545	-	2.1.1.6	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065	302.0
TH2_k127_2820426_17	PFAM Ferredoxin	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005262	278.0
TH2_k127_2820426_18	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	K00125	-	1.17.1.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000007442	282.0
TH2_k127_2820426_19	protein histidine kinase activity	K01768,K11527,K18143	-	2.7.13.3,4.6.1.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000001864	285.0
TH2_k127_2820426_2	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	K02469	-	5.99.1.3	6.202e-279	882.0
TH2_k127_2820426_20	Acetyltransferase (GNAT) domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000002661	259.0
TH2_k127_2820426_21	DDE_Tnp_1-associated	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000008451	235.0
TH2_k127_2820426_22	PFAM methyl-viologen-reducing hydrogenase delta subunit	K14127	-	1.8.98.5,1.8.98.6	0.0000000000000000000000000000000000000000000000000000000000000001172	223.0
TH2_k127_2820426_23	helix_turn_helix, Lux Regulon	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000005215	226.0
TH2_k127_2820426_24	Histidine kinase	K07675	-	2.7.13.3	0.000000000000000000000000000000000000000000000000000000000001767	223.0
TH2_k127_2820426_25	PFAM Cobalamin adenosyltransferase	K00798	-	2.5.1.17	0.0000000000000000000000000000000000000000000000000000001249	200.0
TH2_k127_2820426_26	protein histidine kinase activity	K01768,K11527,K18143	-	2.7.13.3,4.6.1.1	0.000000000000000000000000000000000000000000000000002901	207.0
TH2_k127_2820426_27	acyl-CoA dehydrogenase	K00249	-	1.3.8.7	0.000000000000000000000000000000000000000000001846	178.0
TH2_k127_2820426_28	protein histidine kinase activity	K01768,K11527,K18143	-	2.7.13.3,4.6.1.1	0.000000000000000000000000000000000000000000007164	178.0
TH2_k127_2820426_29	Produces ATP from ADP in the presence of a proton gradient across the membrane	K02120	-	-	0.00000000000000000000000000000000000000000002258	169.0
TH2_k127_2820426_3	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	K03388	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	3.716e-261	833.0
TH2_k127_2820426_30	4Fe-4S dicluster domain	K03390,K16887	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	0.0000000000000000000000000000000000000000003207	164.0
TH2_k127_2820426_31	DSBA-like thioredoxin domain	-	-	-	0.00000000000000000000000000000000000000001248	160.0
TH2_k127_2820426_32	PFAM response regulator receiver	K11443	-	-	0.0000000000000000000000000000000000000008595	152.0
TH2_k127_2820426_33	PFAM transposase, IS4 family protein	-	-	-	0.00000000000000000000000000000000000000115	161.0
TH2_k127_2820426_34	phosphorelay sensor kinase activity	K07638,K07673,K21009	-	2.7.13.3	0.000000000000000000000000000000000000002167	170.0
TH2_k127_2820426_35	Transcriptional regulator, AbiEi antitoxin	-	-	-	0.000000000000000000000000000000000000003209	156.0
TH2_k127_2820426_36	protein histidine kinase activity	K01768,K11527,K18143	-	2.7.13.3,4.6.1.1	0.000000000000000000000000000000000005068	159.0
TH2_k127_2820426_37	4Fe-4S dicluster domain	K00125	-	1.17.1.9	0.000000000000000000000000000000000008876	150.0
TH2_k127_2820426_38	4Fe-4S dicluster domain	K00125,K03646	-	1.17.1.9	0.0000000000000000000000000000000039	141.0
TH2_k127_2820426_39	Produces ATP from ADP in the presence of a proton gradient across the membrane	K02119	-	-	0.0000000000000000000000000000001278	137.0
TH2_k127_2820426_4	PFAM peptidase M3A and M3B, thimet oligopeptidase F	K08602	-	-	1.15e-253	795.0
TH2_k127_2820426_40	Response regulator, receiver	K02030,K03407,K07679,K11443,K13924	-	2.1.1.80,2.7.13.3,3.1.1.61	0.000000000000000000000000000000726	125.0
TH2_k127_2820426_41	zinc finger, SWIM	-	-	-	0.000000000000000000000000000002187	136.0
TH2_k127_2820426_42	PFAM response regulator receiver	K11443	-	-	0.000000000000000000000000000008475	126.0
TH2_k127_2820426_43	PFAM transposase, IS4 family protein	-	-	-	0.000000000000000000000000001502	114.0
TH2_k127_2820426_44	4Fe-4S dicluster domain	K00125,K03646	-	1.17.1.9	0.00000000000000000000000008728	112.0
TH2_k127_2820426_45	Prokaryotic cytochrome b561	-	-	-	0.0000000000000000000182	97.0
TH2_k127_2820426_46	Produces ATP from ADP in the presence of a proton gradient across the membrane	K02121	-	-	0.000000000000000248	87.0
TH2_k127_2820426_47	Histidine kinase-like ATPases	-	-	-	0.000000000000001252	92.0
TH2_k127_2820426_48	ATP synthase subunit C	K02124	-	-	0.00000000000007844	74.0
TH2_k127_2820426_49	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	0.000000001423	69.0
TH2_k127_2820426_5	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	K02117	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600	3.6.3.14,3.6.3.15	1.317e-219	696.0
TH2_k127_2820426_50	Involved in initiation control of chromosome replication	-	-	-	0.000000002205	62.0
TH2_k127_2820426_52	Produces ATP from ADP in the presence of a proton gradient across the membrane	K02122	-	-	0.000006351	53.0
TH2_k127_2820426_53	Von Willebrand factor A domain containing 7	-	-	-	0.000008218	58.0
TH2_k127_2820426_54	sh3 domain protein	K01448	-	3.5.1.28	0.00003358	55.0
TH2_k127_2820426_55	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	0.0000355	46.0
TH2_k127_2820426_56	sh3 domain protein	K01448,K04771	-	3.4.21.107,3.5.1.28	0.00009911	53.0
TH2_k127_2820426_6	PFAM fumarate reductase succinate dehydrogenase flavoprotein	K00239,K00244,K17363	-	1.3.5.1,1.3.5.4,1.3.99.33	4.663e-217	687.0
TH2_k127_2820426_7	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	K01733,K22010	-	4.2.3.1	7.387e-209	662.0
TH2_k127_2820426_8	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	K02118	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976	606.0
TH2_k127_2820426_9	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	K03388	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497	532.0
TH2_k127_2847433_0	ATPase associated with various cellular activities, AAA_5	K03696	-	-	0.0	1304.0
TH2_k127_2847433_1	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	K01873	-	6.1.1.9	0.0	1294.0
TH2_k127_2847433_10	UDP-N-acetylglucosamine 2-epimerase activity	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222	597.0
TH2_k127_2847433_100	PadR family transcriptional regulator	K10947	-	-	0.00000000000000000000000000000000003881	137.0
TH2_k127_2847433_101	-	-	-	-	0.00000000000000000000000000000000009524	138.0
TH2_k127_2847433_102	Sulfotransferase domain	-	-	-	0.0000000000000000000000000000000001907	143.0
TH2_k127_2847433_103	-	-	-	-	0.0000000000000000000000000000001503	126.0
TH2_k127_2847433_104	PFAM EamA-like transporter family	-	-	-	0.000000000000000000000000000001644	125.0
TH2_k127_2847433_105	PFAM Calcium calmodulin dependent protein kinase II	-	-	-	0.000000000000000000000000000001674	125.0
TH2_k127_2847433_106	PFAM DinB family protein	-	-	-	0.00000000000000000000000000005759	123.0
TH2_k127_2847433_107	5-formyltetrahydrofolate cyclo-ligase family	K01934	-	6.3.3.2	0.0000000000000000000000000001078	123.0
TH2_k127_2847433_108	-	-	-	-	0.0000000000000000000000000001313	124.0
TH2_k127_2847433_109	NAD dependent epimerase dehydratase family	K00091	-	1.1.1.219	0.0000000000000000000000000001856	126.0
TH2_k127_2847433_11	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466	616.0
TH2_k127_2847433_110	GIY-YIG catalytic domain	K07461	-	-	0.000000000000000000000000004645	115.0
TH2_k127_2847433_111	Acetyltransferase (GNAT) domain	-	-	-	0.00000000000000000000000002141	112.0
TH2_k127_2847433_112	PFAM helix-turn-helix- domain containing protein, AraC type	K13653	-	-	0.0000000000000000000000003793	111.0
TH2_k127_2847433_113	-	-	-	-	0.000000000000000000000001118	112.0
TH2_k127_2847433_114	CAAX protease self-immunity	K07052,K09696	-	-	0.00000000000000000000001017	110.0
TH2_k127_2847433_115	-	-	-	-	0.00000000000000000000001961	103.0
TH2_k127_2847433_116	Rieske [2Fe-2S] domain	K03886	-	-	0.00000000000000000000002404	106.0
TH2_k127_2847433_117	YhhN family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.00000000000000000000007587	106.0
TH2_k127_2847433_118	Belongs to the phosphoglycerate mutase family	-	-	-	0.00000000000000000000008068	106.0
TH2_k127_2847433_119	Bacterial protein of unknown function (DUF951)	-	-	-	0.0000000000000000004848	88.0
TH2_k127_2847433_12	amino acid	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766	576.0
TH2_k127_2847433_120	Enoyl-(Acyl carrier protein) reductase	-	-	-	0.000000000000000002321	95.0
TH2_k127_2847433_121	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	K07025	-	-	0.000000000000000006998	94.0
TH2_k127_2847433_122	-	-	-	-	0.000000000000000007164	89.0
TH2_k127_2847433_123	NUDIX domain	-	-	-	0.00000000000000001793	89.0
TH2_k127_2847433_124	-	-	-	-	0.0000000000000002054	81.0
TH2_k127_2847433_125	-	-	-	-	0.000000000000001078	91.0
TH2_k127_2847433_126	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	K03885	-	1.6.99.3	0.000000000000005704	75.0
TH2_k127_2847433_127	Cytochrome b(C-terminal)/b6/petD	K00412	-	-	0.000000000000007237	87.0
TH2_k127_2847433_128	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	0.0000000004883	70.0
TH2_k127_2847433_129	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	K00241	-	-	0.000000001453	63.0
TH2_k127_2847433_13	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706	563.0
TH2_k127_2847433_131	PFAM glycosyl transferase family 39	-	-	-	0.0000000225	67.0
TH2_k127_2847433_132	Pfam Anion-transporting ATPase	-	-	-	0.00000003455	59.0
TH2_k127_2847433_133	Lysin motif	-	-	-	0.00000003472	64.0
TH2_k127_2847433_135	Permease family	K02824,K03458,K09016	GO:0003674,GO:0005215,GO:0005350,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0006810,GO:0006855,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0015205,GO:0015210,GO:0015238,GO:0015851,GO:0015855,GO:0015857,GO:0015893,GO:0016020,GO:0016021,GO:0017144,GO:0019860,GO:0022857,GO:0031224,GO:0031226,GO:0034641,GO:0042221,GO:0042493,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072527,GO:0072529,GO:0072531,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1903791,GO:1904082	-	0.0000001865	59.0
TH2_k127_2847433_136	Cytochrome c	K00406,K03889	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	0.0000003568	63.0
TH2_k127_2847433_137	pyridine nucleotide-disulphide oxidoreductase	K03885	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.99.3	0.000001689	53.0
TH2_k127_2847433_138	O-linked N-acetylglucosamine transferase, SPINDLY family	-	-	-	0.000003133	59.0
TH2_k127_2847433_14	SMART alpha amylase, catalytic sub domain	K01176	-	3.2.1.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082	560.0
TH2_k127_2847433_140	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	K00242	-	-	0.0002511	49.0
TH2_k127_2847433_141	SNARE associated Golgi protein	-	-	-	0.000539	43.0
TH2_k127_2847433_142	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	0.0008314	53.0
TH2_k127_2847433_143	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	0.0009782	49.0
TH2_k127_2847433_144	Pfam:DUF2029	-	-	-	0.0009931	51.0
TH2_k127_2847433_15	COG0520 Selenocysteine lyase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301	533.0
TH2_k127_2847433_16	3-deoxy-manno-octulosonate-8-phosphatase activity	K00983,K03270	-	2.7.7.43,3.1.3.45	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621	512.0
TH2_k127_2847433_17	modification enzyme, MiaB family	K18707	-	2.8.4.5	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559	507.0
TH2_k127_2847433_18	Oligopeptidase F	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862	514.0
TH2_k127_2847433_19	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	K03639	-	4.1.99.22	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529	467.0
TH2_k127_2847433_2	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	K00239	-	1.3.5.1,1.3.5.4	1.298e-290	902.0
TH2_k127_2847433_20	Amidohydrolase family	K11540	-	2.1.3.2,3.5.2.3,6.3.5.5	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753	454.0
TH2_k127_2847433_21	Malic enzyme, N-terminal domain	K00027	-	1.1.1.38	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687	455.0
TH2_k127_2847433_22	NeuB family	K01654	-	2.5.1.56	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272	444.0
TH2_k127_2847433_23	His Kinase A (phosphoacceptor) domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989	463.0
TH2_k127_2847433_24	Protein of unknown function (DUF2867)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071	443.0
TH2_k127_2847433_25	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	K02338	-	2.7.7.7	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376	436.0
TH2_k127_2847433_26	DNA binding	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472	438.0
TH2_k127_2847433_27	inositol 2-dehydrogenase activity	K18431	-	2.7.7.82	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739	420.0
TH2_k127_2847433_28	PFAM NMT1 THI5 like domain protein	K02051	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587	413.0
TH2_k127_2847433_29	Bacterial transcriptional activator domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208	429.0
TH2_k127_2847433_3	Catalyzes the synthesis of activated sulfate	K00958	-	2.7.7.4	2.905e-267	832.0
TH2_k127_2847433_30	Belongs to the ATCase OTCase family	K00609	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474	399.0
TH2_k127_2847433_31	transferase activity, transferring glycosyl groups	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783	400.0
TH2_k127_2847433_32	PFAM Monogalactosyldiacylglycerol synthase	K03429	-	2.4.1.315	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774	389.0
TH2_k127_2847433_33	Belongs to the NAD(P)-dependent epimerase dehydratase family	K01784	-	5.1.3.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174	381.0
TH2_k127_2847433_34	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	K01491	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228	372.0
TH2_k127_2847433_35	Belongs to the UPF0173 family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304	369.0
TH2_k127_2847433_36	Enoyl-(Acyl carrier protein) reductase	K00065	-	1.1.1.127	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118	364.0
TH2_k127_2847433_37	PFAM ComEC Rec2-related protein	K02238	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417	377.0
TH2_k127_2847433_38	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	K01497	-	3.5.4.25	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631	344.0
TH2_k127_2847433_39	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123	345.0
TH2_k127_2847433_4	Belongs to the Glu Leu Phe Val dehydrogenases family	K00261	-	1.4.1.3	2.342e-228	712.0
TH2_k127_2847433_40	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	K02041	-	3.6.3.28	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261	341.0
TH2_k127_2847433_41	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	K00240	-	1.3.5.1,1.3.5.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108	324.0
TH2_k127_2847433_42	membrane transporter protein	K07090	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922	323.0
TH2_k127_2847433_43	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	K03595	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414	324.0
TH2_k127_2847433_44	-	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458	337.0
TH2_k127_2847433_45	SMART Nucleotide binding protein, PINc	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327	325.0
TH2_k127_2847433_46	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052	320.0
TH2_k127_2847433_47	'de novo' UMP biosynthetic process	K00762,K01591,K13421,K15334	GO:0003674,GO:0003824,GO:0004588,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.1.1.202,2.4.2.10,4.1.1.23	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737	316.0
TH2_k127_2847433_48	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	K00226,K00254	-	1.3.5.2,1.3.98.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287	316.0
TH2_k127_2847433_49	Deoxynucleoside kinase	K15518	-	2.7.1.113	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464	304.0
TH2_k127_2847433_5	Isocitrate/isopropylmalate dehydrogenase	K00031	-	1.1.1.42	2.625e-218	688.0
TH2_k127_2847433_50	Protein of unknown function (DUF554)	K07150	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731	303.0
TH2_k127_2847433_51	TIGRFAM metal dependent phophohydrolase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931	296.0
TH2_k127_2847433_52	Beta-lactamase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725	310.0
TH2_k127_2847433_53	Protein of unknown function (DUF2867)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112	306.0
TH2_k127_2847433_54	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	K00020,K00042	-	1.1.1.31,1.1.1.60	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324	296.0
TH2_k127_2847433_55	Phosphoribosyl transferase domain	K00759	-	2.4.2.7	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009	290.0
TH2_k127_2847433_56	transferase activity, transferring glycosyl groups	K21011,K21012	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003294	297.0
TH2_k127_2847433_57	ATPases associated with a variety of cellular activities	K02049	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116	287.0
TH2_k127_2847433_58	Serine threonine protein kinase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002584	303.0
TH2_k127_2847433_59	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008019	276.0
TH2_k127_2847433_6	Immune inhibitor A peptidase M6	-	-	-	7.085e-218	695.0
TH2_k127_2847433_60	PFAM binding-protein-dependent transport systems inner membrane component	K02050	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000001486	275.0
TH2_k127_2847433_61	Major facilitator Superfamily	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000004617	276.0
TH2_k127_2847433_62	organic phosphonate transmembrane transporter activity	K02042	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000135	261.0
TH2_k127_2847433_63	Cytochrome b/b6/petB	K00412,K03888	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000001763	253.0
TH2_k127_2847433_64	GDP-mannose mannosyl hydrolase activity	K01515,K03574	-	3.6.1.13,3.6.1.55	0.000000000000000000000000000000000000000000000000000000000000000000000005882	248.0
TH2_k127_2847433_65	DeoR-like helix-turn-helix domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000239	250.0
TH2_k127_2847433_66	Short-chain dehydrogenase reductase sdr	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000001333	230.0
TH2_k127_2847433_67	Prephenate dehydrogenase	K04517	-	1.3.1.12	0.0000000000000000000000000000000000000000000000000000000000000001721	233.0
TH2_k127_2847433_68	transcription factor binding	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000443	251.0
TH2_k127_2847433_69	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	0.000000000000000000000000000000000000000000000000000000000000008688	227.0
TH2_k127_2847433_7	Belongs to the class-I aminoacyl-tRNA synthetase family	K01883	-	6.1.1.16	5.115e-205	647.0
TH2_k127_2847433_70	acetyltransferase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000005548	228.0
TH2_k127_2847433_71	ABC transporter (Permease)	K02042	-	-	0.00000000000000000000000000000000000000000000000000000000000008976	231.0
TH2_k127_2847433_72	Putative sensor	-	-	-	0.0000000000000000000000000000000000000000000000000000000000001803	223.0
TH2_k127_2847433_73	Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase	K01591,K13421	-	2.4.2.10,4.1.1.23	0.000000000000000000000000000000000000000000000000000000000005418	214.0
TH2_k127_2847433_74	PhoQ Sensor	-	-	-	0.0000000000000000000000000000000000000000000000000000000003229	232.0
TH2_k127_2847433_75	MBOAT, membrane-bound O-acyltransferase family	K03739,K19294	-	-	0.000000000000000000000000000000000000000000000000000000002197	217.0
TH2_k127_2847433_76	nUDIX hydrolase	-	-	-	0.000000000000000000000000000000000000000000000000000000003687	204.0
TH2_k127_2847433_77	Acetyltransferase (GNAT) domain	-	-	-	0.000000000000000000000000000000000000000000000000000000004623	211.0
TH2_k127_2847433_78	organic phosphonate transport	K02044	-	-	0.000000000000000000000000000000000000000000000000000000006308	211.0
TH2_k127_2847433_79	homoserine transmembrane transporter activity	-	-	-	0.000000000000000000000000000000000000000000000000000000008042	207.0
TH2_k127_2847433_8	PFAM ABC transporter related	K06158	-	-	4.547e-199	640.0
TH2_k127_2847433_80	deoxyribonucleotide catabolic process	K01081	-	3.1.3.5	0.0000000000000000000000000000000000000000000000000000009405	197.0
TH2_k127_2847433_83	arylsulfatase activity	-	-	-	0.00000000000000000000000000000000000000000000000000009305	207.0
TH2_k127_2847433_85	enterobactin catabolic process	K07214	-	-	0.0000000000000000000000000000000000000000000000000002359	201.0
TH2_k127_2847433_86	cell envelope-related transcriptional attenuator	-	-	-	0.0000000000000000000000000000000000000000000000001963	195.0
TH2_k127_2847433_87	Serine threonine protein kinase	K12132	-	2.7.11.1	0.000000000000000000000000000000000000000000000174	190.0
TH2_k127_2847433_88	PFAM bifunctional deaminase-reductase domain protein	K14654	-	1.1.1.302	0.000000000000000000000000000000000000000000003576	171.0
TH2_k127_2847433_89	membrane-anchored protein conserved in bacteria	-	-	-	0.0000000000000000000000000000000000000000008015	169.0
TH2_k127_2847433_9	PFAM Aminotransferase class I and II	K05825	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045	594.0
TH2_k127_2847433_90	PFAM GCN5-related N-acetyltransferase	-	-	-	0.0000000000000000000000000000000000000000008184	168.0
TH2_k127_2847433_91	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	0.00000000000000000000000000000000000000005843	154.0
TH2_k127_2847433_92	pyridine nucleotide-disulfide oxidoreductase	K03885	-	1.6.99.3	0.0000000000000000000000000000000000000001608	157.0
TH2_k127_2847433_94	Aminoacyl-tRNA editing domain	K19055	-	-	0.000000000000000000000000000000000000006768	151.0
TH2_k127_2847433_95	-	-	-	-	0.000000000000000000000000000000000000007366	150.0
TH2_k127_2847433_96	arylsulfatase activity	-	-	-	0.00000000000000000000000000000000000006309	161.0
TH2_k127_2847433_98	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	K18979	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	0.000000000000000000000000000000000001875	143.0
TH2_k127_2847433_99	Cupin domain	-	-	-	0.000000000000000000000000000000000006976	139.0
TH2_k127_2866804_0	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	K00600	-	2.1.2.1	0.0	1304.0
TH2_k127_2866804_1	PFAM NADH flavin oxidoreductase NADH oxidase	K00317	-	1.5.8.1,1.5.8.2	0.0	1011.0
TH2_k127_2866804_10	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	K02036	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529	344.0
TH2_k127_2866804_11	AI-2E family transporter	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379	336.0
TH2_k127_2866804_12	Linear amide C-N hydrolases, choloylglycine hydrolase family	K01442	-	3.5.1.24	0.000000000000000000000000000000000000000000000000000000000000000000000000002215	266.0
TH2_k127_2866804_13	helix_turn_helix, mercury resistance	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000007483	260.0
TH2_k127_2866804_14	cell adhesion	K05889,K17713	-	1.1.2.6	0.000000000000000000000000000000000000000000001856	175.0
TH2_k127_2866804_15	Low molecular weight phosphotyrosine protein phosphatase	K03741	-	1.20.4.1	0.00000000000000000000000000000000000000008066	156.0
TH2_k127_2866804_16	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	0.00000000000000000000000000000000000009643	148.0
TH2_k127_2866804_17	histone H2A K63-linked ubiquitination	-	-	-	0.00000000000000000000000000000001018	134.0
TH2_k127_2866804_19	PFAM membrane protein of	K08972	-	-	0.00000000000000000002414	94.0
TH2_k127_2866804_2	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	K00763	-	6.3.4.21	1.725e-221	697.0
TH2_k127_2866804_3	isochorismatase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389	433.0
TH2_k127_2866804_4	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	K02038	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797	422.0
TH2_k127_2866804_5	TIGRFAM phosphate binding protein	K02040	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158	395.0
TH2_k127_2866804_6	4Fe-4S binding domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063	392.0
TH2_k127_2866804_7	probably responsible for the translocation of the substrate across the membrane	K02037	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444	385.0
TH2_k127_2866804_8	PFAM peptidase S58, DmpA	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689	384.0
TH2_k127_2866804_9	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	K02036	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539	371.0
TH2_k127_291829_0	Oxidoreductase	-	-	-	7.925e-285	883.0
TH2_k127_291829_1	Belongs to the glycosyl hydrolase 31 family	-	-	-	8.099e-250	791.0
TH2_k127_291829_10	Aminotransferase class-III	K15372	-	2.6.1.55	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008928	509.0
TH2_k127_291829_11	NmrA-like family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976	499.0
TH2_k127_291829_12	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	K02377	-	1.1.1.271	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461	490.0
TH2_k127_291829_13	helix_turn_helix, Lux Regulon	K03556	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045	470.0
TH2_k127_291829_14	Glycosyl transferase, family 2	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791	425.0
TH2_k127_291829_15	PFAM NAD-dependent epimerase dehydratase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483	427.0
TH2_k127_291829_16	PFAM glycosyl transferase group 1	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098	363.0
TH2_k127_291829_17	ABC-2 type transporter	K09690	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708	349.0
TH2_k127_291829_18	PFAM ABC transporter related	K01990	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112	346.0
TH2_k127_291829_19	methyltransferase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799	338.0
TH2_k127_291829_2	beta-galactosidase	K12308	-	3.2.1.23	1.462e-227	719.0
TH2_k127_291829_20	PFAM Glyoxalase bleomycin resistance protein dioxygenase	K07104	-	1.13.11.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421	333.0
TH2_k127_291829_21	Phosphotransferase enzyme family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929	330.0
TH2_k127_291829_22	Glycosyl transferase, family 2	K20444	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646	327.0
TH2_k127_291829_23	alpha-L-arabinofuranosidase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213	331.0
TH2_k127_291829_24	Peptidase M28	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934	321.0
TH2_k127_291829_25	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	K00948	-	2.7.6.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734	316.0
TH2_k127_291829_26	Glycoside hydrolase family 16	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296	306.0
TH2_k127_291829_27	PFAM NAD-dependent epimerase dehydratase	K00067	-	1.1.1.133	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009074	294.0
TH2_k127_291829_28	NurA	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000002027	268.0
TH2_k127_291829_29	Cytidylyltransferase	K07257	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000001037	254.0
TH2_k127_291829_3	Aldehyde dehydrogenase family	K00140	-	1.2.1.18,1.2.1.27	1.496e-222	699.0
TH2_k127_291829_30	helix_turn_helix, mercury resistance	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000001773	244.0
TH2_k127_291829_32	spore germination	K03298	-	-	0.00000000000000000000000000000000000000000000000000000000000747	216.0
TH2_k127_291829_33	Protein of unknown function (DUF541)	K09807	-	-	0.00000000000000000000000000000000000000000000000000000004987	205.0
TH2_k127_291829_34	-	-	-	-	0.0000000000000000000000000000000000000000000000000000008832	201.0
TH2_k127_291829_35	CAAX protease self-immunity	-	-	-	0.000000000000000000000000000000000000000000000000000004358	203.0
TH2_k127_291829_36	DNA-binding transcription factor activity	K02274	-	1.9.3.1	0.000000000000000000000000000000000000000000000000003281	187.0
TH2_k127_291829_37	Aminoglycoside 3-N-acetyltransferase	K00662	-	2.3.1.81	0.00000000000000000000000000000000000000000008608	169.0
TH2_k127_291829_38	ABC-2 family transporter protein	K01992	-	-	0.000000000000000000000000000000000000000001177	173.0
TH2_k127_291829_39	Protein of unknown function (DUF1232)	-	-	-	0.0000000000000000000000000000000000001793	145.0
TH2_k127_291829_4	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	8.961e-203	638.0
TH2_k127_291829_40	Acetyltransferase (GNAT) domain	-	-	-	0.00000000000000000000006998	111.0
TH2_k127_291829_41	Cupin domain	-	-	-	0.0000000000000000009024	91.0
TH2_k127_291829_42	PFAM ABC-2 type transporter	K01992	-	-	0.0000000000000002217	92.0
TH2_k127_291829_43	-	-	-	-	0.0000000000000009893	78.0
TH2_k127_291829_44	Membrane	-	GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0051301,GO:0071944	-	0.00000000000002905	78.0
TH2_k127_291829_45	PFAM Magnesium chelatase, subunit ChlI	K07391	-	-	0.000000000003718	72.0
TH2_k127_291829_46	Glycosyl hydrolase family 10	K01181	-	3.2.1.8	0.000000000008292	73.0
TH2_k127_291829_47	-	-	-	-	0.00000000002743	75.0
TH2_k127_291829_48	PFAM SNARE associated Golgi protein	-	-	-	0.00000001795	57.0
TH2_k127_291829_5	Domain of unknown function DUF87	K06915	-	-	2.428e-201	643.0
TH2_k127_291829_6	teichoic acid transport	K01990,K09689,K09691	-	3.6.3.38	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176	608.0
TH2_k127_291829_7	Thi4 family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855	568.0
TH2_k127_291829_8	SAF	K01654	-	2.5.1.56	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418	516.0
TH2_k127_291829_9	lipid-A-disaccharide synthase activity	K00748	-	2.4.1.182	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973	515.0
TH2_k127_2919436_0	His Kinase A (phosphoacceptor) domain	-	-	-	0.0000000000000000000000000000000000000000000000000000002201	211.0
TH2_k127_2925880_0	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	K00198	-	1.2.7.4	8.816e-273	852.0
TH2_k127_2925880_1	4Fe-4S dicluster domain	K00196	-	-	0.0000000000000000000000000000000000000000000000000000000000139	214.0
TH2_k127_2925880_2	Reductase C-terminal	K00362,K00529,K18088	-	1.18.1.3,1.7.1.15	0.000004234	51.0
TH2_k127_2937385_0	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	K01586	-	4.1.1.20	0.00000000000000000000000000000000000000000000000000000000000000000000009184	248.0
TH2_k127_2937385_1	PFAM Glyoxalase bleomycin resistance protein dioxygenase	K05606	-	5.1.99.1	0.000000000000000000000000000000000000002319	148.0
TH2_k127_2937385_2	Septum formation initiator	-	-	-	0.00000000001986	69.0
TH2_k127_2983370_0	helix_turn_helix, Lux Regulon	K03556	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657	601.0
TH2_k127_2983370_1	-	-	-	-	0.000000000000000126	82.0
TH2_k127_300552_0	Tetratricopeptide TPR_2 repeat protein	-	-	-	0.0	1359.0
TH2_k127_300552_1	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	K03596	-	-	1.599e-305	944.0
TH2_k127_300552_10	PFAM ABC-3 protein	K09816,K09819	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188	360.0
TH2_k127_300552_11	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605	359.0
TH2_k127_300552_12	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513	344.0
TH2_k127_300552_13	PFAM ABC transporter related	K09820,K11710	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242	325.0
TH2_k127_300552_14	PFAM ABC transporter related	K01990	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923	310.0
TH2_k127_300552_15	PFAM peptidase S1 and S6, chymotrypsin Hap	K08070	-	1.3.1.74	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000407	301.0
TH2_k127_300552_16	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	K14696	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002676	295.0
TH2_k127_300552_17	RNase_H superfamily	K07502	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006995	289.0
TH2_k127_300552_18	COG2211 Na melibiose symporter and related	K03292	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000239	292.0
TH2_k127_300552_19	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	K08681	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	0.000000000000000000000000000000000000000000000000000000000000000000000000000002825	267.0
TH2_k127_300552_2	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	2.682e-223	704.0
TH2_k127_300552_20	Ig-like domain from next to BRCA1 gene	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000006479	293.0
TH2_k127_300552_21	Methyltransferase domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000003086	261.0
TH2_k127_300552_22	Belongs to the cytidylate kinase family. Type 1 subfamily	K00945	-	2.7.4.25	0.000000000000000000000000000000000000000000000000000000000000000000000000004882	258.0
TH2_k127_300552_23	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	K00943	-	2.7.4.9	0.0000000000000000000000000000000000000000000000000000000000000000000000000131	256.0
TH2_k127_300552_24	DUF218 domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000005156	253.0
TH2_k127_300552_25	Zinc-uptake complex component A periplasmic	K02077,K09818	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000002029	253.0
TH2_k127_300552_26	ABC-2 family transporter protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000003356	243.0
TH2_k127_300552_27	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000001145	241.0
TH2_k127_300552_28	SdpI/YhfL protein family	-	-	-	0.00000000000000000000000000000000000000000000000000001121	196.0
TH2_k127_300552_29	PFAM transposase IS4 family protein	-	-	-	0.00000000000000000000000000000000000000000000000002256	190.0
TH2_k127_300552_3	PFAM glycosyl transferase, family 51	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665	614.0
TH2_k127_300552_31	His Kinase A (phosphoacceptor) domain	K02484	-	2.7.13.3	0.0000000000000000000000000000000000000000001087	176.0
TH2_k127_300552_32	Creatinine amidohydrolase	K01470	-	3.5.2.10	0.000000000000000000000000000000000000000004125	166.0
TH2_k127_300552_33	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	0.0000000000000000000000000000000000000001877	169.0
TH2_k127_300552_34	Putative regulatory protein	-	-	-	0.00000000000000000000000000000000000002838	146.0
TH2_k127_300552_35	PFAM regulatory protein GntR HTH	K07979	-	-	0.00000000000000000000000000000000001695	139.0
TH2_k127_300552_36	diguanylate cyclase	-	-	-	0.000000000000000000000000000000003028	140.0
TH2_k127_300552_37	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	0.00000000000000000000000000000003071	131.0
TH2_k127_300552_38	lysyltransferase activity	K07027	-	-	0.0000000000000000000000000000002942	136.0
TH2_k127_300552_4	oligosaccharyl transferase activity	K07151	-	2.4.99.18	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014	539.0
TH2_k127_300552_40	Phosphate acyltransferases	K00655	-	2.3.1.51	0.00000000000000000000000000004725	126.0
TH2_k127_300552_41	Transposase IS66 family	-	-	-	0.0000000000000000000000000006039	117.0
TH2_k127_300552_42	carboxylic ester hydrolase activity	-	-	-	0.000000000000000000000000002595	113.0
TH2_k127_300552_43	Protein of unknown function (DUF952)	K00799,K01560,K09705,K21420	-	2.3.2.29,2.5.1.18,3.8.1.2	0.00000000000000000000000000697	113.0
TH2_k127_300552_44	PFAM phospholipid glycerol acyltransferase	K00655	-	2.3.1.51	0.0000000000000000000000002643	116.0
TH2_k127_300552_45	Belongs to the sigma-70 factor family. ECF subfamily	K03088	-	-	0.000000000000000000000005183	108.0
TH2_k127_300552_46	WD40-like Beta Propeller Repeat	K03641	-	-	0.0000000000000000000002132	112.0
TH2_k127_300552_47	Methyltransferase domain	-	-	-	0.000000000000000000001759	103.0
TH2_k127_300552_48	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	0.0000000000000000000139	99.0
TH2_k127_300552_49	Transferrin receptor-like dimerisation domain	K01301	-	3.4.17.21	0.000000000000000642	92.0
TH2_k127_300552_5	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	K06215	-	4.3.3.6	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776	501.0
TH2_k127_300552_50	bacterial-type flagellum-dependent cell motility	-	-	-	0.0000000000000006936	93.0
TH2_k127_300552_51	Thioesterase	K07107	-	-	0.0000000000004221	73.0
TH2_k127_300552_52	Alpha/beta hydrolase family	-	-	-	0.000000000001965	71.0
TH2_k127_300552_53	ubiquitin binding	-	GO:0000407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005776,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016236,GO:0032182,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0061919	-	0.000000000008038	80.0
TH2_k127_300552_56	Protein of unknown function (DUF1706)	-	-	-	0.00000000005325	70.0
TH2_k127_300552_57	Peptidase family S51	K05995	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	0.0000000199	61.0
TH2_k127_300552_58	PFAM Sulfate transporter antisigma-factor antagonist STAS	K04749	-	-	0.0000001297	59.0
TH2_k127_300552_59	Flp/Fap pilin component	K02651	-	-	0.0000008931	52.0
TH2_k127_300552_6	PFAM band 7 protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293	437.0
TH2_k127_300552_60	COG3293 Transposase and inactivated derivatives	-	-	-	0.00003745	46.0
TH2_k127_300552_61	sh3 domain protein	-	-	-	0.0001186	56.0
TH2_k127_300552_62	regulation of response to stimulus	K01126,K21449	-	3.1.4.46	0.0002229	48.0
TH2_k127_300552_63	-	-	-	-	0.0008582	48.0
TH2_k127_300552_7	PFAM glycosyl transferase group 1	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807	436.0
TH2_k127_300552_8	short-chain dehydrogenase reductase SDR	K12454	-	5.1.3.10	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194	434.0
TH2_k127_300552_9	Uncharacterized membrane protein (DUF2298)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335	430.0
TH2_k127_3063890_0	-	-	-	-	0.0000000000000000000000000000000000000000000000000001009	200.0
TH2_k127_3073402_0	ROK family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751	334.0
TH2_k127_3073402_1	Psort location Cytoplasmic, score 8.87	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006624	294.0
TH2_k127_3073402_2	Transposase DDE domain	-	-	-	0.00000000000000000000000000000000000000000000002892	175.0
TH2_k127_3073402_3	Transposase DDE domain	-	-	-	0.00000000000000000000000000000000000000005769	158.0
TH2_k127_3073402_5	MFS/sugar transport protein	K03292	-	-	0.000000000000000000000000000000000006906	153.0
TH2_k127_3073402_6	Transposase DDE domain	-	-	-	0.000000000002419	70.0
TH2_k127_312065_0	ATP-dependent transcriptional regulator	K03556	-	-	0.00000000000000000000000000000000002236	146.0
TH2_k127_312065_1	Hydrolases of the alpha beta superfamily	K06889	-	-	0.00000000000000000000000000000001518	141.0
TH2_k127_312065_2	-	-	-	-	0.000000000000000227	81.0
TH2_k127_312065_3	Domain of unknown function (DUF333)	K14475	-	-	0.000000000002009	79.0
TH2_k127_3376259_0	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	7.001e-206	647.0
TH2_k127_3376259_1	alanine dehydrogenase activity	K00259	GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009653,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030312,GO:0030435,GO:0032502,GO:0036293,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	0.00000000000000000000000000000000000000000000000008655	183.0
TH2_k127_3376259_2	Pyruvate kinase, barrel domain	K00873	-	2.7.1.40	0.00000000000000000000000000002258	120.0
TH2_k127_3377946_0	Glycosyl transferase, family 2	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941	310.0
TH2_k127_3377946_2	lipid binding	-	-	-	0.00002042	46.0
TH2_k127_3398795_0	Domain of unknown function DUF11	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109	323.0
TH2_k127_3398795_1	HD domain	K18967	-	2.7.7.65	0.000000000000000000000000000000000000000000000000000000000000000000000000001338	272.0
TH2_k127_3398795_2	response regulator	-	-	-	0.0000000000000000000000000000000000000000000000000000000001915	206.0
TH2_k127_3403393_0	PFAM ATP-binding region, ATPase domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675	328.0
TH2_k127_3403393_1	transcription factor binding	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000001431	280.0
TH2_k127_3403393_2	PFAM ATP-binding region, ATPase domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000008426	278.0
TH2_k127_3403393_3	Belongs to the MenA family. Type 1 subfamily	K02548	-	2.5.1.74	0.000000000000000000000000000000000000000000001251	169.0
TH2_k127_3433973_0	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	K01872	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	0.0	1132.0
TH2_k127_3433973_1	homoserine kinase activity	K00823,K07250	-	2.6.1.19,2.6.1.22	0.0	1127.0
TH2_k127_3433973_10	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	K00790	-	2.5.1.7	1.119e-198	627.0
TH2_k127_3433973_11	FAD dependent oxidoreductase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021	567.0
TH2_k127_3433973_12	Belongs to the citrate synthase family	K01647	-	2.3.3.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631	535.0
TH2_k127_3433973_13	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	K21071	-	2.7.1.11,2.7.1.90	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245	527.0
TH2_k127_3433973_14	ferrous iron transmembrane transporter activity	K04759	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329	522.0
TH2_k127_3433973_15	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	K03593	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858	504.0
TH2_k127_3433973_16	Domain of unknown function (DUF3520)	K07114	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004	458.0
TH2_k127_3433973_17	Peptidase dimerisation domain protein	K01436	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169	428.0
TH2_k127_3433973_18	Catalyzes the reversible oxidation of malate to oxaloacetate	K00024	-	1.1.1.37	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116	388.0
TH2_k127_3433973_19	AAA domain, putative AbiEii toxin, Type IV TA system	K01990	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873	376.0
TH2_k127_3433973_2	Belongs to the GcvT family	-	-	-	0.0	1023.0
TH2_k127_3433973_20	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	K07082	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165	364.0
TH2_k127_3433973_21	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	K00384	-	1.8.1.9	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413	352.0
TH2_k127_3433973_22	PFAM PSP1 domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198	349.0
TH2_k127_3433973_23	PFAM molybdopterin binding domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916	351.0
TH2_k127_3433973_24	FAD dependent oxidoreductase	K00303	-	1.5.3.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189	343.0
TH2_k127_3433973_25	epimerase	K00329,K00356	-	1.6.5.3,1.6.99.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527	333.0
TH2_k127_3433973_26	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00331	-	1.6.5.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712	314.0
TH2_k127_3433973_27	Wd40 repeat-containing protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841	321.0
TH2_k127_3433973_28	Phosphoglycerate mutase family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001523	285.0
TH2_k127_3433973_29	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	K00338,K03615	-	1.6.5.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000004639	274.0
TH2_k127_3433973_3	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	K00820	-	2.6.1.16	1.127e-298	925.0
TH2_k127_3433973_30	Baseplate J-like protein	K01218	-	3.2.1.78	0.0000000000000000000000000000000000000000000000000000000000000000000000002338	265.0
TH2_k127_3433973_31	PFAM Radical SAM domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000002775	237.0
TH2_k127_3433973_32	N-6 DNA Methylase	-	-	-	0.000000000000000000000000000000000000000000000000000000000001621	218.0
TH2_k127_3433973_33	MafB19-like deaminase	K01493	-	3.5.4.12	0.00000000000000000000000000000000000000000000000000000000004468	207.0
TH2_k127_3433973_34	phosphatidate phosphatase activity	K19302	-	3.6.1.27	0.000000000000000000000000000000000000000000000000000007337	201.0
TH2_k127_3433973_35	Tetratricopeptide repeat	-	-	-	0.000000000000000000000000000000000000000000000000002497	199.0
TH2_k127_3433973_36	GlcNAc-PI de-N-acetylase	-	-	-	0.00000000000000000000000000000000000000000000000001403	190.0
TH2_k127_3433973_37	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	0.0000000000000000000000000000000000000000000000004936	179.0
TH2_k127_3433973_38	PhoQ Sensor	-	-	-	0.0000000000000000000000000000000000000000000000006391	190.0
TH2_k127_3433973_39	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	0.00000000000000000000000000000000000000000000191	172.0
TH2_k127_3433973_4	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	-	-	-	4.768e-294	914.0
TH2_k127_3433973_40	aspartic-type endopeptidase activity	K02236,K02506,K02654	-	3.4.23.43	0.0000000000000000000000000000000000000000000162	171.0
TH2_k127_3433973_41	Subtilase family	K13274,K14645	-	-	0.000000000000000000000000000000000000002632	169.0
TH2_k127_3433973_42	Subtilase family	K13274,K14645	-	-	0.000000000000000000000000000000000000005576	168.0
TH2_k127_3433973_43	Ornithine cyclodeaminase/mu-crystallin family	K01750	-	4.3.1.12	0.0000000000000000000000000000000000002366	143.0
TH2_k127_3433973_44	Archease protein family (MTH1598/TM1083)	-	-	-	0.0000000000000000000000000000000000549	138.0
TH2_k127_3433973_45	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	K07447	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	0.0000000000000000000000000000000001188	136.0
TH2_k127_3433973_46	Histidine phosphatase superfamily (branch 1)	K01834	-	5.4.2.11	0.00000000000000000000000000000000291	139.0
TH2_k127_3433973_47	PFAM peptidase M14, carboxypeptidase A	-	-	-	0.0000000000000000000000000129	121.0
TH2_k127_3433973_48	AMP binding	-	-	-	0.00000000000000000006877	100.0
TH2_k127_3433973_49	peptidase U32	K08303	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	0.000000000000000001782	88.0
TH2_k127_3433973_5	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00333,K13378	-	1.6.5.3	9.434e-251	786.0
TH2_k127_3433973_50	Belongs to the GbsR family	-	-	-	0.000000000000000009312	90.0
TH2_k127_3433973_51	Transcriptional regulator	-	-	-	0.000000000000001946	83.0
TH2_k127_3433973_52	sh3 domain protein	K01227,K03642	-	3.2.1.96	0.00000000000003478	85.0
TH2_k127_3433973_53	PspC domain	K03973	-	-	0.00000000005991	66.0
TH2_k127_3433973_55	Putative Flp pilus-assembly TadE/G-like	-	-	-	0.000000003503	69.0
TH2_k127_3433973_56	Endonuclease/Exonuclease/phosphatase family	-	-	-	0.000000004266	70.0
TH2_k127_3433973_57	protein conserved in bacteria	-	-	-	0.000000004788	59.0
TH2_k127_3433973_58	PFAM TadE family protein	-	-	-	0.000000005908	64.0
TH2_k127_3433973_6	Belongs to the RtcB family	K14415	-	6.5.1.3	4.642e-234	731.0
TH2_k127_3433973_60	cGMP-dependent protein kinase activity	K07376	-	2.7.11.12	0.0000002797	63.0
TH2_k127_3433973_62	Peptidase_C39 like family	-	-	-	0.0000009146	61.0
TH2_k127_3433973_63	TadE-like protein	-	-	-	0.000003033	59.0
TH2_k127_3433973_64	PFAM FeoA family protein	K04758	-	-	0.00001179	52.0
TH2_k127_3433973_65	PFAM TadE family protein	-	-	-	0.00001465	57.0
TH2_k127_3433973_66	HEPN domain	-	-	-	0.00009953	48.0
TH2_k127_3433973_67	serine-type aminopeptidase activity	K14475	-	-	0.0001612	50.0
TH2_k127_3433973_68	Nucleotidyltransferase domain	-	-	-	0.0007427	42.0
TH2_k127_3433973_7	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	K01354	-	3.4.21.83	1.181e-226	722.0
TH2_k127_3433973_8	AAA ATPase domain	-	-	-	2.354e-222	736.0
TH2_k127_3433973_9	Flavin containing amine oxidoreductase	-	-	-	6.773e-219	690.0
TH2_k127_3448658_0	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	K00169,K03737	-	1.2.7.1	0.0	1481.0
TH2_k127_3448658_1	Catalyzes the conversion of dihydroorotate to orotate	K00226	-	1.3.98.1	0.0000000000000000001673	88.0
TH2_k127_3463662_0	Domain of unknown function (DUF362)	-	-	-	0.000000000000000000000000000000000000000000000000000000000000001088	231.0
TH2_k127_3463662_1	Nitroreductase family	K19285	-	1.5.1.38	0.00000000000000000000000000000000000000000000000003298	184.0
TH2_k127_3493056_0	PFAM alpha-2-macroglobulin domain protein	K06894	-	-	0.0	1199.0
TH2_k127_3493056_1	PFAM Dak phosphatase	K07030	-	-	7.283e-203	646.0
TH2_k127_3493056_10	PFAM UbiA prenyltransferase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441	374.0
TH2_k127_3493056_11	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	K03438	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342	364.0
TH2_k127_3493056_12	Cell wall formation	K00075	-	1.3.1.98	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083	356.0
TH2_k127_3493056_13	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398	371.0
TH2_k127_3493056_14	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	K06969	-	2.1.1.191	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124	353.0
TH2_k127_3493056_15	SMART serine threonine protein kinase	K12132	-	2.7.11.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564	349.0
TH2_k127_3493056_16	ErfK ybiS ycfS ynhG family protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378	336.0
TH2_k127_3493056_17	Magnesium transport protein CorA	K03284	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728	333.0
TH2_k127_3493056_18	Belongs to the D-alanine--D-alanine ligase family	K01921	-	6.3.2.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762	312.0
TH2_k127_3493056_19	PFAM SMP-30 Gluconolaconase LRE domain protein	K14274	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422	310.0
TH2_k127_3493056_2	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	K01929	-	6.3.2.10	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498	601.0
TH2_k127_3493056_20	Ribosomal RNA methyltransferase RrmJ FtsJ	K06442	-	2.1.1.226,2.1.1.227	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522	304.0
TH2_k127_3493056_21	TIGRFAM mevalonate kinase	K00869	-	2.7.1.36	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001288	287.0
TH2_k127_3493056_22	peptidyl-tyrosine sulfation	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000008674	286.0
TH2_k127_3493056_23	Belongs to the ribulose-phosphate 3-epimerase family	K01783	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	0.000000000000000000000000000000000000000000000000000000000000000000000000001743	259.0
TH2_k127_3493056_24	Essential for recycling GMP and indirectly, cGMP	K00942	-	2.7.4.8	0.0000000000000000000000000000000000000000000000000000000000000000000000003674	254.0
TH2_k127_3493056_25	PFAM cell wall hydrolase autolysin	K01448	-	3.5.1.28	0.0000000000000000000000000000000000000000000000000000000000000000000002633	250.0
TH2_k127_3493056_26	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000001003	245.0
TH2_k127_3493056_27	ferrous iron binding	K06990,K09141	-	-	0.000000000000000000000000000000000000000000000000000000000000000002333	233.0
TH2_k127_3493056_28	ErfK ybiS ycfS ynhG family protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000003596	227.0
TH2_k127_3493056_29	-	-	-	-	0.000000000000000000000000000000000000000000000000000000000001465	216.0
TH2_k127_3493056_3	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	K01925	-	6.3.2.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389	551.0
TH2_k127_3493056_30	TIGRFAM cell division protein FtsW	K03588	-	-	0.000000000000000000000000000000000000000000000000000000000094	220.0
TH2_k127_3493056_31	-	-	-	-	0.000000000000000000000000000000000000000000000000000000004491	202.0
TH2_k127_3493056_32	PFAM Rhomboid family protein	K19225	-	3.4.21.105	0.000000000000000000000000000000000000000000000000000224	195.0
TH2_k127_3493056_33	Protein of unknown function (DUF971)	-	-	-	0.000000000000000000000000000000000000000002961	157.0
TH2_k127_3493056_34	PFAM GGDEF domain containing protein	-	-	-	0.00000000000000000000000000000000000000003259	165.0
TH2_k127_3493056_35	Belongs to the MraZ family	K03925	-	-	0.0000000000000000000000000000000000000002967	154.0
TH2_k127_3493056_36	PFAM flavin reductase domain protein, FMN-binding	-	-	-	0.000000000000000000000000000000000000004846	151.0
TH2_k127_3493056_37	DSBA-like thioredoxin domain	-	-	-	0.00000000000000000000000000000000000009932	152.0
TH2_k127_3493056_39	PFAM Diacylglycerol kinase, catalytic	-	-	-	0.000000000000000000000000000000009943	140.0
TH2_k127_3493056_4	Penicillin-binding protein, dimerisation domain	K03587	-	3.4.16.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869	512.0
TH2_k127_3493056_40	-	-	-	-	0.00000000000000000000000000000005927	130.0
TH2_k127_3493056_41	LysM domain	K21449,K22278	-	3.5.1.104	0.000000000000000000000001448	114.0
TH2_k127_3493056_42	ATP-dependent transcriptional regulator, MalT-like, LuxR family	K03556	-	-	0.00000000000000000000000659	102.0
TH2_k127_3493056_43	ribosomal protein L28	K02902	-	-	0.00000000000000000002849	91.0
TH2_k127_3493056_44	Asp23 family, cell envelope-related function	-	-	-	0.00000000000000000005051	93.0
TH2_k127_3493056_45	Diguanylate cyclase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032879,GO:0042710,GO:0044010,GO:0044464,GO:0044764,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0065007,GO:0071944,GO:0090605,GO:0090609	-	0.00000000000007161	76.0
TH2_k127_3493056_47	DNA polymerase beta domain protein region	K07076	-	-	0.0002309	48.0
TH2_k127_3493056_5	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	K01000	-	2.7.8.13	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192	481.0
TH2_k127_3493056_6	nitrite transmembrane transporter activity	K02532	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986	464.0
TH2_k127_3493056_7	Belongs to the MurCDEF family	K01924	-	6.3.2.8	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536	459.0
TH2_k127_3493056_8	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	K02563	-	2.4.1.227	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504	418.0
TH2_k127_3493056_9	GHMP kinases N terminal domain	K01597	-	4.1.1.33	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237	383.0
TH2_k127_3504312_0	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	K00850	-	2.7.1.11	3.524e-209	661.0
TH2_k127_3504312_1	Serine threonine protein kinase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000004978	254.0
TH2_k127_3504312_2	Psort location CytoplasmicMembrane, score	-	-	-	0.0000000002283	73.0
TH2_k127_3507542_0	glycolate biosynthetic process	K01091	-	3.1.3.18	0.0000000000000000000000000000000000000000000000000000000000000006173	226.0
TH2_k127_3507542_1	FIST N domain	-	-	-	0.00000000000000000000000000000000001219	140.0
TH2_k127_3507542_2	PhoQ Sensor	K07682	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	0.000000000000000000000000000003336	123.0
TH2_k127_3552280_0	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	K01491	-	1.5.1.5,3.5.4.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547	436.0
TH2_k127_3552280_1	AAA domain, putative AbiEii toxin, Type IV TA system	K01990	-	-	0.00000000000000000000000000001032	124.0
TH2_k127_3552280_2	Peptidase family M28	-	-	-	0.0002323	52.0
TH2_k127_3577578_0	TIGRFAM Acetoacetyl-CoA synthase	K01907	-	6.2.1.16	3.714e-316	979.0
TH2_k127_3577578_1	Belongs to the formate--tetrahydrofolate ligase family	K00288,K01938	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.5.1.5,3.5.4.9,6.3.4.3	1.441e-311	965.0
TH2_k127_3577578_10	Homocysteine S-methyltransferase	K00547	-	2.1.1.10	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481	433.0
TH2_k127_3577578_11	Putative pyruvate format-lyase activating enzyme (DUF1786)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073	427.0
TH2_k127_3577578_12	4Fe-4S binding domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519	406.0
TH2_k127_3577578_13	von Willebrand factor (vWF) type A domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411	400.0
TH2_k127_3577578_14	peptidase dimerisation domain protein	K01436	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159	378.0
TH2_k127_3577578_15	Trimethylamine methyltransferase (MTTB)	K14083	-	2.1.1.250	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164	382.0
TH2_k127_3577578_16	ATPases associated with a variety of cellular activities	K01990	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602	355.0
TH2_k127_3577578_17	Trimethylamine methyltransferase (MTTB)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532	345.0
TH2_k127_3577578_18	Ribosomal protein S1	K02945	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774	340.0
TH2_k127_3577578_19	Membrane dipeptidase (Peptidase family M19)	K01273	-	3.4.13.19	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099	328.0
TH2_k127_3577578_2	PFAM glycoside hydrolase, family 3 domain protein	K05349	-	3.2.1.21	4.844e-301	937.0
TH2_k127_3577578_20	PFAM ATP-binding region, ATPase domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476	341.0
TH2_k127_3577578_21	peptidase dimerisation domain protein	K01295	-	3.4.17.11	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426	314.0
TH2_k127_3577578_22	Ig-like domain from next to BRCA1 gene	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001293	319.0
TH2_k127_3577578_23	Arylsulfatase a	K01133	-	3.1.6.6	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006353	289.0
TH2_k127_3577578_24	Peptidase S9, prolyl oligopeptidase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000126	282.0
TH2_k127_3577578_25	Methyltransferase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000001804	258.0
TH2_k127_3577578_26	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	K06153	-	3.6.1.27	0.0000000000000000000000000000000000000000000000000000000000000000000006033	246.0
TH2_k127_3577578_28	PFAM aspartate glutamate uridylate kinase	K06981	-	2.7.4.26	0.000000000000000000000000000000000000000000000000000000000000000003204	236.0
TH2_k127_3577578_29	Methionine synthase B12-binding module cap domain protein	K00548,K14084	-	2.1.1.13	0.00000000000000000000000000000000000000000000000000000000000000003342	229.0
TH2_k127_3577578_3	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	4.051e-254	834.0
TH2_k127_3577578_30	Thioesterase superfamily	-	-	-	0.000000000000000000000000000000000000000000000000000000000000002791	222.0
TH2_k127_3577578_31	phosphatidylinositol metabolic process	-	-	-	0.00000000000000000000000000000000000000000000000000000000000002998	226.0
TH2_k127_3577578_32	methyltransferase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000005238	224.0
TH2_k127_3577578_33	4 iron, 4 sulfur cluster binding	-	-	-	0.0000000000000000000000000000000000000000000000000000000000001431	221.0
TH2_k127_3577578_34	PFAM Arsenical pump membrane protein	K03893	-	-	0.0000000000000000000000000000000000000000000000000000000000003684	218.0
TH2_k127_3577578_35	Trimethylamine methyltransferase (MTTB)	K14083	-	2.1.1.250	0.00000000000000000000000000000000000000000000000000000000001877	225.0
TH2_k127_3577578_36	homoserine transmembrane transporter activity	K06600,K06895	-	-	0.0000000000000000000000000000000000000000000000000000000001311	210.0
TH2_k127_3577578_37	ABC-2 family transporter protein	K01992	-	-	0.000000000000000000000000000000000000000000000000000000001873	208.0
TH2_k127_3577578_38	Uncharacterized protein domain (DUF2202)	-	-	-	0.000000000000000000000000000000000000000000000000000000002669	207.0
TH2_k127_3577578_39	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	K00969	-	2.7.7.18	0.00000000000000000000000000000000000000000000000000000001741	203.0
TH2_k127_3577578_4	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	K00281,K00283	-	1.4.4.2	4.835e-235	736.0
TH2_k127_3577578_40	PFAM major facilitator superfamily MFS_1	K08223	-	-	0.000000000000000000000000000000000000000000000000000007338	207.0
TH2_k127_3577578_41	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	0.00000000000000000000000000000000000000000000000000001219	199.0
TH2_k127_3577578_42	Nucleoside 2-deoxyribosyltransferase like	-	-	-	0.00000000000000000000000000000000000000001086	158.0
TH2_k127_3577578_43	THIoesterase	K18700	-	3.1.2.29	0.000000000000000000000000000000000005705	141.0
TH2_k127_3577578_44	Protein of unknown function (DUF2721)	-	-	-	0.00000000000000000000000000000000004762	138.0
TH2_k127_3577578_45	DNA-binding transcription factor activity	K03892	-	-	0.0000000000000000000000000000000002574	134.0
TH2_k127_3577578_46	COG1055 Na H antiporter NhaD and related arsenite permeases	-	-	-	0.00000000000000000000000000000000392	136.0
TH2_k127_3577578_47	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	K02437	-	-	0.000000000000000000000000000000116	129.0
TH2_k127_3577578_48	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	K00820	-	2.6.1.16	0.0000000000000000000000000000002358	126.0
TH2_k127_3577578_49	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	K07032	-	-	0.000000000000000000000000000001373	124.0
TH2_k127_3577578_5	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	K00282	-	1.4.4.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495	591.0
TH2_k127_3577578_51	PFAM regulatory protein GntR HTH	-	-	-	0.0000000000000000000003015	106.0
TH2_k127_3577578_52	Transcriptional regulator PadR-like family	-	-	-	0.00000000000000000006367	93.0
TH2_k127_3577578_54	Sporulation and spore germination	-	-	-	0.000000000000001685	92.0
TH2_k127_3577578_57	PAP2 superfamily	-	-	-	0.0000004757	61.0
TH2_k127_3577578_58	-	-	-	-	0.0000005858	62.0
TH2_k127_3577578_6	PFAM phosphoesterase, RecJ domain protein	K07462	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984	556.0
TH2_k127_3577578_60	-	-	-	-	0.00004254	55.0
TH2_k127_3577578_61	PFAM extracellular solute-binding protein family 1	K02040	-	-	0.0006036	50.0
TH2_k127_3577578_62	-	-	-	-	0.0009931	50.0
TH2_k127_3577578_7	introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX	K03404,K03405	-	6.6.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597	542.0
TH2_k127_3577578_8	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	K00773	-	2.4.2.29	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464	469.0
TH2_k127_3577578_9	Belongs to the amidase family	K02433	-	6.3.5.6,6.3.5.7	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272	470.0
TH2_k127_3618979_0	PFAM peptidase S45 penicillin amidase	K01434	-	3.5.1.11	1.159e-208	680.0
TH2_k127_3618979_1	PFAM Aldehyde ferredoxin oxidoreductase	K03738	-	1.2.7.5	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902	486.0
TH2_k127_3651541_0	Belongs to the class-I aminoacyl-tRNA synthetase family	K01869	-	6.1.1.4	0.0	1211.0
TH2_k127_3651541_1	Heat shock 70 kDa protein	K04043	-	-	2.126e-316	977.0
TH2_k127_3651541_10	adenylyl cyclase class-3 4 guanylyl cyclase	K01768	-	4.6.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884	584.0
TH2_k127_3651541_11	C-terminal domain of alpha-glycerophosphate oxidase	K00111	-	1.1.5.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978	529.0
TH2_k127_3651541_12	Binding-protein-dependent transport system inner membrane component	K02034,K15582	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013	492.0
TH2_k127_3651541_13	Belongs to the ABC transporter superfamily	K02032,K10823	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642	465.0
TH2_k127_3651541_14	N-4 methylation of cytosine	K00590	-	2.1.1.113	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701	482.0
TH2_k127_3651541_15	ATPases associated with a variety of cellular activities	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795	461.0
TH2_k127_3651541_16	Belongs to the ABC transporter superfamily	K02031	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853	455.0
TH2_k127_3651541_17	Helicase conserved C-terminal domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501	457.0
TH2_k127_3651541_18	FAD linked oxidase domain protein	K00103,K16653	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.3.8,1.1.98.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108	435.0
TH2_k127_3651541_19	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	K03705	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142	422.0
TH2_k127_3651541_2	Participates in initiation and elongation during chromosome replication	K02314	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	4.767e-278	880.0
TH2_k127_3651541_20	nitrogen compound transport	K02033	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135	428.0
TH2_k127_3651541_21	PFAM IstB domain protein ATP-binding protein	K02315	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166	417.0
TH2_k127_3651541_22	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	K00604	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975	382.0
TH2_k127_3651541_23	PFAM Glycosyl transferase family 2	K20534	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161	381.0
TH2_k127_3651541_24	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	K03686,K05516	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759	379.0
TH2_k127_3651541_25	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701	368.0
TH2_k127_3651541_26	ABC-2 family transporter protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967	362.0
TH2_k127_3651541_27	PFAM transglutaminase domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849	373.0
TH2_k127_3651541_28	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	K00077	-	1.1.1.169	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402	347.0
TH2_k127_3651541_29	polysaccharide deacetylase	K01406	-	3.4.24.40	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751	334.0
TH2_k127_3651541_3	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	K00864	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	2.473e-262	815.0
TH2_k127_3651541_30	peptidase dimerisation domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325	316.0
TH2_k127_3651541_31	Psort location Cytoplasmic, score	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508	294.0
TH2_k127_3651541_32	PFAM diacylglycerol kinase catalytic region	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001598	296.0
TH2_k127_3651541_33	helix_turn_helix, Lux Regulon	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008124	279.0
TH2_k127_3651541_34	Ig-like domain from next to BRCA1 gene	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000001755	300.0
TH2_k127_3651541_35	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	K02346	-	2.7.7.7	0.0000000000000000000000000000000000000000000000000000000000000000000000000001557	273.0
TH2_k127_3651541_36	pfkB family carbohydrate kinase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000006752	260.0
TH2_k127_3651541_37	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	K02259	-	-	0.00000000000000000000000000000000000000000000000000000000000000000007659	243.0
TH2_k127_3651541_38	PFAM Rubrerythrin	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000002182	233.0
TH2_k127_3651541_39	ABC-2 family transporter protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000005722	233.0
TH2_k127_3651541_4	uridine kinase	K00876	-	2.7.1.48	3.924e-223	707.0
TH2_k127_3651541_40	Bifunctional nuclease	K08999	-	-	0.0000000000000000000000000000000000000000000000000000000000003859	217.0
TH2_k127_3651541_41	conserved protein (DUF2174)	-	-	-	0.000000000000000000000000000000000000000000000000000000000009516	214.0
TH2_k127_3651541_42	Cupin 2, conserved barrel domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000002532	206.0
TH2_k127_3651541_43	Iron permease FTR1 family	K07243	-	-	0.00000000000000000000000000000000000000000000000000000000003256	215.0
TH2_k127_3651541_44	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	0.0000000000000000000000000000000000000000000000000000000005301	211.0
TH2_k127_3651541_45	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	0.0000000000000000000000000000000000000000000000000000000007133	207.0
TH2_k127_3651541_46	sigma-70 region 2 domain protein	K03088	-	-	0.00000000000000000000000000000000000000000000000000000005755	201.0
TH2_k127_3651541_47	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	K03801	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	0.000000000000000000000000000000000000000000000000005523	190.0
TH2_k127_3651541_48	Clostripain family	-	-	-	0.00000000000000000000000000000000000000000000000001967	194.0
TH2_k127_3651541_49	GAF domain	-	-	-	0.000000000000000000000000000000000000000000000000213	192.0
TH2_k127_3651541_5	Two component regulator propeller	K00936	-	2.7.13.3	1.254e-216	717.0
TH2_k127_3651541_50	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	0.000000000000000000000000000000000000000000000001218	179.0
TH2_k127_3651541_51	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	0.000000000000000000000000000000000000000000000017	183.0
TH2_k127_3651541_52	Histidine kinase	-	-	-	0.000000000000000000000000000000000000000001319	181.0
TH2_k127_3651541_53	FeoA	K03709	-	-	0.00000000000000000000000000000000000000002788	161.0
TH2_k127_3651541_54	diguanylate cyclase	-	-	-	0.00000000000000000000000000000000000000005357	167.0
TH2_k127_3651541_55	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	K03687	-	-	0.00000000000000000000000000000000000002744	150.0
TH2_k127_3651541_56	COG3293 Transposase and inactivated derivatives	-	-	-	0.000000000000000000000000000000001871	130.0
TH2_k127_3651541_57	VIT family	-	-	-	0.0000000000000000000000000000003408	132.0
TH2_k127_3651541_58	TIGRFAM primosome, DnaD subunit	-	-	-	0.0000000000000000000000000000553	124.0
TH2_k127_3651541_59	Cytochrome c	-	-	-	0.0000000000000000000000000001193	125.0
TH2_k127_3651541_6	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	K00639	-	2.3.1.29	2.168e-195	615.0
TH2_k127_3651541_60	WD40-like Beta Propeller Repeat	K03641	-	-	0.000000000000000000000000003198	125.0
TH2_k127_3651541_61	Belongs to the UPF0758 family	K03630	-	-	0.00000000000000000000000001023	116.0
TH2_k127_3651541_62	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	0.000000000000000000001456	97.0
TH2_k127_3651541_63	histidine kinase A domain protein	-	-	-	0.000000000000000000002244	104.0
TH2_k127_3651541_64	phosphoglycerate mutase family	-	-	-	0.000000000000000000002948	101.0
TH2_k127_3651541_65	Cysteine-rich secretory protein family	-	-	-	0.000000000000000000006765	105.0
TH2_k127_3651541_66	Domain of unknown function (DUF4870)	-	-	-	0.0000000000000000006451	90.0
TH2_k127_3651541_67	Ig-like domain from next to BRCA1 gene	-	-	-	0.00000000000000006338	93.0
TH2_k127_3651541_68	Ig-like domain from next to BRCA1 gene	K17987	-	-	0.0000000000000007764	93.0
TH2_k127_3651541_69	glycosyl transferase family 28	-	-	-	0.00000000001761	68.0
TH2_k127_3651541_7	Protein tyrosine kinase	-	-	-	5.344e-194	629.0
TH2_k127_3651541_70	Nodulation protein S (NodS)	-	-	-	0.000000001171	63.0
TH2_k127_3651541_72	-	-	-	-	0.000000003551	61.0
TH2_k127_3651541_73	COG0739 Membrane proteins related to metalloendopeptidases	K08642	-	-	0.000000003755	70.0
TH2_k127_3651541_75	Transcriptional regulator	-	-	-	0.0000002179	58.0
TH2_k127_3651541_76	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	0.0000002864	63.0
TH2_k127_3651541_78	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	0.00002599	49.0
TH2_k127_3651541_79	Domain of unknown function (DUF1998)	K06877,K07451	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	0.00006729	48.0
TH2_k127_3651541_8	Myo-inositol-1-phosphate synthase, GAPDH domain protein	K01858	-	5.5.1.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009278	588.0
TH2_k127_3651541_80	-	-	-	-	0.0001109	47.0
TH2_k127_3651541_81	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	0.000134	44.0
TH2_k127_3651541_82	Belongs to the glycosyl hydrolase 5 (cellulase A) family	K01179	-	3.2.1.4	0.0004358	48.0
TH2_k127_3651541_83	protein kinase activity	-	-	-	0.0005274	48.0
TH2_k127_3651541_9	Bacterial extracellular solute-binding proteins, family 5 Middle	K02035	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755	609.0
TH2_k127_371982_0	aldehyde ferredoxin oxidoreductase	K03738	-	1.2.7.5	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603	522.0
TH2_k127_371982_1	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	K01897	-	6.2.1.3	0.0000000000000000000000000000000000000002386	160.0
TH2_k127_371982_2	Membrane dipeptidase (Peptidase family M19)	-	-	-	0.0000000000004318	78.0
TH2_k127_3779227_0	O-Methyltransferase	-	-	-	0.0000000000000000000000000002602	119.0
TH2_k127_3779227_1	PFAM secretion protein HlyD family protein	-	-	-	0.0000000000000000000002627	108.0
TH2_k127_3796713_0	ATPase, P-type (transporting), HAD superfamily, subfamily IC	K01537	-	3.6.3.8	3.675e-314	982.0
TH2_k127_3796713_1	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	K03798	-	-	4.657e-289	898.0
TH2_k127_3796713_10	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	K01897	-	6.2.1.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956	581.0
TH2_k127_3796713_100	peroxiredoxin activity	-	-	-	0.000000000000000000000000000001773	128.0
TH2_k127_3796713_101	Psort location CytoplasmicMembrane, score	-	-	-	0.000000000000000000000000000004797	126.0
TH2_k127_3796713_102	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	K01633,K07589	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564	1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8	0.00000000000000000000000001147	113.0
TH2_k127_3796713_103	Transcriptional regulatory protein, C terminal	K10697	-	-	0.0000000000000000000000001765	109.0
TH2_k127_3796713_104	Two component transcriptional regulator, winged helix family	K07658	-	-	0.0000000000000000000000006239	108.0
TH2_k127_3796713_105	PFAM Adenylate and Guanylate cyclase catalytic domain	K01768	-	4.6.1.1	0.000000000000000000000001163	108.0
TH2_k127_3796713_106	Uncharacterized ACR, COG1430	K09005	-	-	0.000000000000000000000002726	108.0
TH2_k127_3796713_108	carboxylic ester hydrolase activity	-	-	-	0.0000000000000000000000561	104.0
TH2_k127_3796713_109	Phosphotransferase	K01007	-	2.7.9.2	0.00000000000000000000007179	109.0
TH2_k127_3796713_11	Gamma-glutamyltranspeptidase 2-like	K00681	-	2.3.2.2,3.4.19.13	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431	557.0
TH2_k127_3796713_110	ubiE/COQ5 methyltransferase family	-	-	-	0.0000000000000000000000883	108.0
TH2_k127_3796713_111	arsR family	K21903	-	-	0.000000000000000000002415	96.0
TH2_k127_3796713_112	competence protein F	-	-	-	0.000000000000000001753	94.0
TH2_k127_3796713_113	Transglycosylase associated protein	-	-	-	0.0000000000000001416	85.0
TH2_k127_3796713_114	His Kinase A (phosphoacceptor) domain	-	-	-	0.000000000000001832	80.0
TH2_k127_3796713_115	Phospholipid methyltransferase	-	-	-	0.0000000000001646	78.0
TH2_k127_3796713_117	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	0.00000000008113	68.0
TH2_k127_3796713_119	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	K11991	-	3.5.4.33	0.000000008228	59.0
TH2_k127_3796713_12	efflux transmembrane transporter activity	K02004	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488	543.0
TH2_k127_3796713_120	Acyl-ACP thioesterase	K07107	-	-	0.00000001368	58.0
TH2_k127_3796713_121	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	0.000001224	59.0
TH2_k127_3796713_123	Streptomycin adenylyltransferase	K05593	-	-	0.000009667	55.0
TH2_k127_3796713_124	Bardet-Biedl syndrome 2 protein homolog	K16747	GO:0000003,GO:0000226,GO:0001085,GO:0001103,GO:0001501,GO:0001578,GO:0001894,GO:0001895,GO:0003006,GO:0003008,GO:0003012,GO:0003013,GO:0003018,GO:0003352,GO:0003356,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005902,GO:0005929,GO:0006810,GO:0006892,GO:0006893,GO:0006928,GO:0006936,GO:0006939,GO:0006996,GO:0007010,GO:0007017,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007288,GO:0007368,GO:0007369,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007600,GO:0007601,GO:0007610,GO:0008015,GO:0008104,GO:0008134,GO:0008150,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010468,GO:0010605,GO:0010629,GO:0014820,GO:0014824,GO:0014829,GO:0015031,GO:0015630,GO:0015833,GO:0016020,GO:0016043,GO:0016192,GO:0019221,GO:0019222,GO:0019953,GO:0021537,GO:0021543,GO:0021544,GO:0021756,GO:0021761,GO:0021766,GO:0021987,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0030030,GO:0030031,GO:0030154,GO:0030317,GO:0030534,GO:0030900,GO:0031090,GO:0031253,GO:0031514,GO:0031667,GO:0032095,GO:0032096,GO:0032098,GO:0032099,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032400,GO:0032401,GO:0032402,GO:0032420,GO:0032421,GO:0032501,GO:0032502,GO:0032504,GO:0032870,GO:0032879,GO:0032886,GO:0032991,GO:0033036,GO:0033059,GO:0033210,GO:0033365,GO:0034097,GO:0034464,GO:0034613,GO:0035082,GO:0035150,GO:0035296,GO:0036064,GO:0038108,GO:0040008,GO:0040011,GO:0040012,GO:0040014,GO:0040015,GO:0040018,GO:0042221,GO:0042310,GO:0042311,GO:0042592,GO:0042886,GO:0042995,GO:0043001,GO:0043005,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043473,GO:0044085,GO:0044320,GO:0044321,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044782,GO:0045184,GO:0045444,GO:0045494,GO:0045926,GO:0045927,GO:0046907,GO:0048193,GO:0048232,GO:0048468,GO:0048513,GO:0048515,GO:0048518,GO:0048519,GO:0048583,GO:0048585,GO:0048598,GO:0048609,GO:0048638,GO:0048639,GO:0048640,GO:0048731,GO:0048854,GO:0048856,GO:0048869,GO:0048870,GO:0048871,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050880,GO:0050896,GO:0050953,GO:0051093,GO:0051094,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051270,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0051674,GO:0051704,GO:0051716,GO:0051875,GO:0051877,GO:0051904,GO:0051905,GO:0060170,GO:0060249,GO:0060255,GO:0060271,GO:0060295,GO:0060296,GO:0060322,GO:0060632,GO:0061448,GO:0061512,GO:0061951,GO:0065007,GO:0065008,GO:0070121,GO:0070491,GO:0070727,GO:0070887,GO:0070925,GO:0071310,GO:0071345,GO:0071495,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0072659,GO:0090066,GO:0090150,GO:0097458,GO:0097722,GO:0097746,GO:0097755,GO:0097756,GO:0098588,GO:0098590,GO:0098858,GO:0098862,GO:0098876,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:1902019,GO:1903441,GO:1905515,GO:1990778,GO:2000145	-	0.00001168	58.0
TH2_k127_3796713_125	ThiS family	K03154	-	-	0.00003292	49.0
TH2_k127_3796713_126	Uncharacterised protein family UPF0102	K07460	-	-	0.00004279	51.0
TH2_k127_3796713_127	Acyl-ACP thioesterase	-	-	-	0.0003525	44.0
TH2_k127_3796713_13	PFAM response regulator receiver	K02282	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339	485.0
TH2_k127_3796713_14	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	K02257	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409	457.0
TH2_k127_3796713_15	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	K00088	-	1.1.1.205	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472	456.0
TH2_k127_3796713_16	Receptor family ligand binding region	K01999	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324	449.0
TH2_k127_3796713_17	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	K03086	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437	445.0
TH2_k127_3796713_18	-	K01992	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462	438.0
TH2_k127_3796713_19	Branched-chain amino acid transport system / permease component	K01998	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044	437.0
TH2_k127_3796713_2	PBP superfamily domain	K03750,K07219	-	2.10.1.1	9.934e-281	877.0
TH2_k127_3796713_20	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	K01756	-	4.3.2.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327	421.0
TH2_k127_3796713_21	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	K00266	-	1.4.1.13,1.4.1.14	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328	423.0
TH2_k127_3796713_22	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	K01754	-	4.3.1.19	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213	412.0
TH2_k127_3796713_23	Branched-chain amino acid transport system / permease component	K01997	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444	414.0
TH2_k127_3796713_24	Major facilitator Superfamily	K08217	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095	411.0
TH2_k127_3796713_25	-	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381	406.0
TH2_k127_3796713_26	Lysin motif	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567	403.0
TH2_k127_3796713_27	PFAM ABC transporter related	K01990	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364	395.0
TH2_k127_3796713_28	oligosaccharyl transferase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365	392.0
TH2_k127_3796713_29	transferase activity, transferring glycosyl groups	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762	384.0
TH2_k127_3796713_3	MacB-like periplasmic core domain	K02004	-	-	1.015e-274	870.0
TH2_k127_3796713_30	Winged helix DNA-binding domain	K09927	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882	382.0
TH2_k127_3796713_31	PFAM Radical SAM domain protein	K22227	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026	376.0
TH2_k127_3796713_32	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	K01939	-	6.3.4.4	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135	380.0
TH2_k127_3796713_33	histidine kinase, dimerisation and phosphoacceptor region	K07777	-	2.7.13.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743	374.0
TH2_k127_3796713_34	ATP hydrolysis coupled proton transport	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425	376.0
TH2_k127_3796713_35	PFAM type II secretion system protein	K12511	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003	359.0
TH2_k127_3796713_36	Lipid kinase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164	355.0
TH2_k127_3796713_37	D-isomer specific 2-hydroxyacid dehydrogenase	K00058,K16843	-	1.1.1.310,1.1.1.399,1.1.1.95	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787	354.0
TH2_k127_3796713_38	PFAM type II secretion system protein	K12510	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258	349.0
TH2_k127_3796713_4	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	7.978e-274	852.0
TH2_k127_3796713_40	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	K00791	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265	342.0
TH2_k127_3796713_41	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	K07442	-	2.1.1.219,2.1.1.220	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575	339.0
TH2_k127_3796713_42	Branched-chain amino acid ATP-binding cassette transporter	K01995	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315	332.0
TH2_k127_3796713_43	MacB-like periplasmic core domain	K02004	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474	340.0
TH2_k127_3796713_44	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	K02003	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415	326.0
TH2_k127_3796713_45	Belongs to the enoyl-CoA hydratase isomerase family	K15866	-	5.3.3.18	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071	326.0
TH2_k127_3796713_46	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	K01802	-	5.2.1.8	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182	327.0
TH2_k127_3796713_47	ATPases associated with a variety of cellular activities	K01990	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809	321.0
TH2_k127_3796713_48	oligosaccharyl transferase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668	328.0
TH2_k127_3796713_49	PFAM secretion protein HlyD family protein	K02005	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062	323.0
TH2_k127_3796713_5	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	K02274	-	1.9.3.1	6.286e-266	837.0
TH2_k127_3796713_50	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	K02275	-	1.9.3.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067	320.0
TH2_k127_3796713_51	ABC transporter	K01996	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006	314.0
TH2_k127_3796713_52	Threonyl alanyl tRNA synthetase SAD	K07050	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771	311.0
TH2_k127_3796713_53	PP-loop family	K21947	-	2.8.1.15	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365	310.0
TH2_k127_3796713_54	ATPases associated with a variety of cellular activities	K02003	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255	304.0
TH2_k127_3796713_55	Creatinine amidohydrolase	K01470	-	3.5.2.10	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258	300.0
TH2_k127_3796713_56	Endonuclease/Exonuclease/phosphatase family	K01142	-	3.1.11.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461	294.0
TH2_k127_3796713_57	transferase activity, transferring glycosyl groups	K00754	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001528	300.0
TH2_k127_3796713_58	Psort location CytoplasmicMembrane, score	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002621	293.0
TH2_k127_3796713_59	PFAM ABC transporter related	K02003	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000001232	278.0
TH2_k127_3796713_6	PFAM type II secretion system protein E	K02283	-	-	4.939e-231	722.0
TH2_k127_3796713_60	glycosyl transferase group 1	K08256	-	2.4.1.345	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000232	292.0
TH2_k127_3796713_61	Pyruvate phosphate dikinase, PEP pyruvate binding domain	K01007	-	2.7.9.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000003174	295.0
TH2_k127_3796713_62	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	K02003	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000004443	271.0
TH2_k127_3796713_63	Bacterial periplasmic substrate-binding proteins	K02030	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000001654	264.0
TH2_k127_3796713_64	COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases	K12972	-	1.1.1.79,1.1.1.81	0.00000000000000000000000000000000000000000000000000000000000000000000002636	255.0
TH2_k127_3796713_65	PFAM GTP cyclohydrolase I	K01495	-	3.5.4.16	0.0000000000000000000000000000000000000000000000000000000000000000000001386	244.0
TH2_k127_3796713_66	-	K01992	-	-	0.000000000000000000000000000000000000000000000000000000000000000000001205	243.0
TH2_k127_3796713_67	Leucine carboxyl methyltransferase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000001546	245.0
TH2_k127_3796713_68	PFAM cytochrome c oxidase, subunit III	K02276,K02299	-	1.9.3.1	0.0000000000000000000000000000000000000000000000000000000000000000002955	238.0
TH2_k127_3796713_69	ABC-2 family transporter protein	K01992	-	-	0.000000000000000000000000000000000000000000000000000000000000000004248	235.0
TH2_k127_3796713_7	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	K01299	-	3.4.17.19	7.468e-197	625.0
TH2_k127_3796713_70	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000008853	256.0
TH2_k127_3796713_71	Serine threonine protein kinase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000001947	246.0
TH2_k127_3796713_72	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	K03564	-	1.11.1.15	0.000000000000000000000000000000000000000000000000000000000000009918	219.0
TH2_k127_3796713_73	Major facilitator Superfamily	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000124	231.0
TH2_k127_3796713_74	-	-	-	-	0.00000000000000000000000000000000000000000000000000000000000005566	233.0
TH2_k127_3796713_75	Flp pilus assembly protein CpaB	K02279	-	-	0.0000000000000000000000000000000000000000000000000000000000002174	225.0
TH2_k127_3796713_76	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	K02897	-	-	0.0000000000000000000000000000000000000000000000000000000000002316	219.0
TH2_k127_3796713_77	Ornithine cyclodeaminase/mu-crystallin family	K01750	-	4.3.1.12	0.0000000000000000000000000000000000000000000000000000000000006596	219.0
TH2_k127_3796713_78	EamA-like transporter family	-	-	-	0.0000000000000000000000000000000000000000000000000000000001186	214.0
TH2_k127_3796713_79	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	K05808	-	-	0.0000000000000000000000000000000000000000000000000000000006178	207.0
TH2_k127_3796713_8	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527	614.0
TH2_k127_3796713_80	Two component transcriptional regulator, LuxR family	-	-	-	0.000000000000000000000000000000000000000000000000000000001046	209.0
TH2_k127_3796713_81	phosphinothricin N-acetyltransferase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000002284	199.0
TH2_k127_3796713_82	Leucine carboxyl methyltransferase	-	-	-	0.00000000000000000000000000000000000000000000000000002383	199.0
TH2_k127_3796713_83	NOG31153 non supervised orthologous group	-	-	-	0.00000000000000000000000000000000000000000000000000009046	195.0
TH2_k127_3796713_84	HupE / UreJ protein	K03192	-	-	0.0000000000000000000000000000000000000000000000000002715	192.0
TH2_k127_3796713_85	Acetyltransferase (GNAT) domain	-	-	-	0.00000000000000000000000000000000000000000000000000166	187.0
TH2_k127_3796713_86	methyltransferase	-	-	-	0.00000000000000000000000000000000000000000000000001755	184.0
TH2_k127_3796713_87	Electron transport protein SCO1 SenC	K07152	-	-	0.00000000000000000000000000000000000000000000000007883	184.0
TH2_k127_3796713_88	phosphorelay signal transduction system	-	-	-	0.000000000000000000000000000000000000000000001159	168.0
TH2_k127_3796713_89	Hypothetical methyltransferase	-	-	-	0.00000000000000000000000000000000000000000006348	170.0
TH2_k127_3796713_9	MacB-like periplasmic core domain	K02004	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393	578.0
TH2_k127_3796713_90	mitochondrial respiratory chain complex IV assembly	K14998	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	0.0000000000000000000000000000000000000000008145	166.0
TH2_k127_3796713_91	Leucine carboxyl methyltransferase	-	-	-	0.000000000000000000000000000000000000000003411	165.0
TH2_k127_3796713_92	PFAM NUDIX hydrolase	-	-	-	0.00000000000000000000000000000000000000001674	163.0
TH2_k127_3796713_94	acyl-phosphate glycerol-3-phosphate acyltransferase activity	K08591	-	2.3.1.15	0.00000000000000000000000000000000000005009	152.0
TH2_k127_3796713_95	DinB family	-	-	-	0.0000000000000000000000000000000000006967	143.0
TH2_k127_3796713_96	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	K01993	-	-	0.000000000000000000000000000000000001847	153.0
TH2_k127_3796713_97	domain, Protein	-	-	-	0.000000000000000000000000000000000003615	150.0
TH2_k127_3796713_99	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	K01993	-	-	0.000000000000000000000000000000001925	145.0
TH2_k127_3832293_0	Sulfate transporter	K03321	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001042	294.0
TH2_k127_3832293_1	sh3 domain protein	K01448,K04771	-	3.4.21.107,3.5.1.28	0.00000003111	63.0
TH2_k127_3838762_0	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	K03752	-	2.7.7.77	0.000000000000000000000000000000000000000000000000000006029	197.0
TH2_k127_3838762_1	Universal stress protein	-	-	-	0.0000000000000000000000000000000000001957	145.0
TH2_k127_3838762_2	PFAM Radical SAM domain protein	K04069	-	1.97.1.4	0.000000000000000000079	89.0
TH2_k127_3847195_0	metallocarboxypeptidase activity	K05996	-	3.4.17.18	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331	455.0
TH2_k127_3847195_1	-	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514	405.0
TH2_k127_3847195_2	PFAM Response regulator receiver domain	K11624	-	-	0.00000000000000000000000000000000000000000000000000000000000186	215.0
TH2_k127_3847195_3	N-terminal 7TM region of histidine kinase	K07673	-	2.7.13.3	0.00000000000000000000000000000000000000000000000000139	199.0
TH2_k127_3852743_0	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	K00254	GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.5.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704	312.0
TH2_k127_3852743_1	Peptidase, S9A B C family, catalytic domain protein	-	-	-	0.000001476	61.0
TH2_k127_3930225_0	Coenzyme A transferase	K01039	-	2.8.3.12	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541	315.0
TH2_k127_3930225_1	Coenzyme A transferase	K01040	-	2.8.3.12	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004033	289.0
TH2_k127_3930225_2	methyltransferase activity	-	-	-	0.0000000000000000000000000003838	119.0
TH2_k127_3930225_3	Protein of unknown function (DUF1706)	-	-	-	0.00001281	55.0
TH2_k127_3930225_4	spore germination	K03298	-	-	0.0001465	48.0
TH2_k127_3935903_0	DNA restriction-modification system	-	-	-	0.0000000000000000000000000000000000000000000000000000000001546	218.0
TH2_k127_3935903_1	TIGRFAM addiction module toxin, Txe YoeB family	K19158	-	-	0.00000000000000000000000000000000005762	136.0
TH2_k127_3935903_2	Antitoxin component of a toxin-antitoxin (TA) module	K19159	-	-	0.0000000000000006063	81.0
TH2_k127_3935903_3	-	-	-	-	0.00000000000008407	83.0
TH2_k127_4035219_0	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	K10562	-	3.6.3.17	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492	415.0
TH2_k127_4035219_1	ABC transporter permease protein	K10440	-	-	0.00000000000000000000000000000000000000000000000000000000004963	217.0
TH2_k127_4035219_2	ABC-type sugar transport system periplasmic component	K10439	-	-	0.0000000000000000000000000000000000000000002558	172.0
TH2_k127_4035219_3	Diguanylate cyclase	-	-	-	0.00000000000000000000000000000001307	136.0
TH2_k127_4035219_4	pfkB family carbohydrate kinase	-	-	-	0.0000000000000000000000000000026	133.0
TH2_k127_4075394_0	DNA polymerase	K02337,K14162	-	2.7.7.7	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411	606.0
TH2_k127_4075394_1	PFAM alpha-2-macroglobulin domain protein	K06894	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639	594.0
TH2_k127_4135020_0	CoA-transferase activity	K01039	-	2.8.3.12	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815	391.0
TH2_k127_4135020_1	Coenzyme A transferase	K01040	-	2.8.3.12	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185	317.0
TH2_k127_4135020_2	Flavin containing amine oxidoreductase	-	-	-	0.0000000000004978	69.0
TH2_k127_4197931_0	nuclear chromosome segregation	-	-	-	1.338e-254	810.0
TH2_k127_4197931_1	PFAM VanW family protein	-	-	-	1.839e-194	624.0
TH2_k127_4197931_11	tetraacyldisaccharide 4'-kinase activity	K09791	-	-	0.0000000000000000000000003454	106.0
TH2_k127_4197931_13	PBS lyase HEAT-like repeat	-	-	-	0.00000006208	62.0
TH2_k127_4197931_14	Phosphate acyltransferases	K00655	-	2.3.1.51	0.0000254	55.0
TH2_k127_4197931_15	-	-	-	-	0.0005623	44.0
TH2_k127_4197931_16	amine dehydrogenase activity	-	-	-	0.000666	54.0
TH2_k127_4197931_2	PFAM aldo keto reductase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478	531.0
TH2_k127_4197931_3	domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154	398.0
TH2_k127_4197931_4	metallopeptidase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788	356.0
TH2_k127_4197931_5	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459	344.0
TH2_k127_4197931_6	dolichyl monophosphate biosynthetic process	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004786	282.0
TH2_k127_4197931_7	PFAM major facilitator superfamily MFS_1	-	-	-	0.0000000000000000000000000000000000000000000000000000000000001301	228.0
TH2_k127_4197931_8	carbohydrate transport	K02027,K10117,K17318	-	-	0.0000000000000000000000000000000000000000000001208	186.0
TH2_k127_4197931_9	methyltransferase activity	K21310	-	2.1.1.334	0.000000000000000000000000000000000000001505	154.0
TH2_k127_4247971_0	Binding-protein-dependent transport system inner membrane component	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448	468.0
TH2_k127_4247971_1	PFAM major facilitator superfamily MFS_1	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655	371.0
TH2_k127_4247971_2	TIGRFAM oligopeptide dipeptide ABC transporter	K02031,K02032	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293	338.0
TH2_k127_4247971_3	SpoU rRNA Methylase family	K03218,K03437,K21514	-	2.1.1.185,2.1.1.208	0.0000000000000000000000000000000000000000000000000000000000000000000000001756	262.0
TH2_k127_4247971_4	PFAM binding-protein-dependent transport systems inner membrane component	K02033	-	-	0.00000000000000000000000000000000000000000000000000000000000000006818	229.0
TH2_k127_4247971_5	Acetyltransferase (GNAT) domain	-	-	-	0.000000000000000000000000000000001911	139.0
TH2_k127_4247971_6	Methyltransferase domain	-	-	-	0.000000000000000000004057	104.0
TH2_k127_4399842_0	Belongs to the IlvD Edd family	K01687	-	4.2.1.9	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065	556.0
TH2_k127_4399842_1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	K03086	-	-	0.00000000000386	74.0
TH2_k127_4399842_2	Transposase	-	-	-	0.000008717	59.0
TH2_k127_441076_0	DNA photolyase domain protein	K01669	-	4.1.99.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677	359.0
TH2_k127_441076_1	PFAM major facilitator superfamily MFS_1	K08151	-	-	0.00000004569	57.0
TH2_k127_4475208_0	COG0863 DNA modification methylase	K00571,K00590	-	2.1.1.113,2.1.1.72	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242	388.0
TH2_k127_4475208_1	PFAM transposase IS3 IS911 family protein	K07497	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001949	292.0
TH2_k127_4475208_10	Cell envelope-related transcriptional attenuator	-	-	-	0.00000000000000000000000009948	120.0
TH2_k127_4475208_11	PAS fold	-	-	-	0.00000000000000000002732	107.0
TH2_k127_4475208_12	Cyclic nucleotide-monophosphate binding domain	K09766	-	-	0.00000000000000196	85.0
TH2_k127_4475208_13	-	-	-	-	0.0000000000001278	78.0
TH2_k127_4475208_14	-	-	-	-	0.0000000000002975	80.0
TH2_k127_4475208_15	His Kinase A (phosphoacceptor) domain	-	-	-	0.00000000001365	75.0
TH2_k127_4475208_16	-	-	-	-	0.00001139	54.0
TH2_k127_4475208_2	metallopeptidase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000002892	219.0
TH2_k127_4475208_3	Two component transcriptional regulator, winged helix family	-	-	-	0.0000000000000000000000000000000000000000000000000000001288	204.0
TH2_k127_4475208_4	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	K02257	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	0.0000000000000000000000000000000000000000212	164.0
TH2_k127_4475208_5	GAF domain	K02482	-	2.7.13.3	0.00000000000000000000000000000000000000002124	176.0
TH2_k127_4475208_6	PFAM Transposase IS3 IS911	K07497	-	-	0.0000000000000000000000000000000000000003565	152.0
TH2_k127_4475208_7	-	-	-	-	0.00000000000000000000000000000000000162	156.0
TH2_k127_4475208_8	TIGRFAM conserved repeat domain	-	-	-	0.000000000000000000000000000114	131.0
TH2_k127_4475208_9	PFAM Formylglycine-generating sulfatase enzyme	K18912	-	1.14.99.50	0.000000000000000000000000001663	123.0
TH2_k127_4479996_0	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	K00058,K11216	-	1.1.1.399,1.1.1.95,2.7.1.189	0.0	1240.0
TH2_k127_4479996_1	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	K03782	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	0.0	1237.0
TH2_k127_4479996_10	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	K01710	-	4.2.1.46	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581	470.0
TH2_k127_4479996_11	PFAM Glycosyl transferase family 2	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567	459.0
TH2_k127_4479996_12	PFAM glycoside hydrolase family 29 (alpha-L-fucosidase)	K01206	-	3.2.1.51	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446	455.0
TH2_k127_4479996_13	Aldehyde ferredoxin oxidoreductase, N-terminal domain	K03738	-	1.2.7.5	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649	455.0
TH2_k127_4479996_14	Short-chain dehydrogenase reductase SDR	K08679	-	5.1.3.6	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105	432.0
TH2_k127_4479996_15	N-acetylglucosaminylinositol deacetylase activity	K01463	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994	422.0
TH2_k127_4479996_16	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	K00784	-	3.1.26.11	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652	419.0
TH2_k127_4479996_17	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	K00973	-	2.7.7.24	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013	413.0
TH2_k127_4479996_18	PFAM glycosyl transferase group 1	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283	363.0
TH2_k127_4479996_2	PFAM cell divisionFtsK SpoIIIE	K03466	-	-	5.521e-236	753.0
TH2_k127_4479996_20	cellulose binding	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986	355.0
TH2_k127_4479996_21	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772	327.0
TH2_k127_4479996_22	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008644	336.0
TH2_k127_4479996_23	polysaccharide biosynthetic process	K16694	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471	308.0
TH2_k127_4479996_24	DDE superfamily endonuclease	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225	295.0
TH2_k127_4479996_25	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000003322	281.0
TH2_k127_4479996_27	NmrA-like family	K00329,K00356	-	1.6.5.3,1.6.99.3	0.000000000000000000000000000000000000000000000000000000000000000000000005602	254.0
TH2_k127_4479996_28	lysyltransferase activity	K07027	-	-	0.000000000000000000000000000000000000000000000000000000000000000000001059	248.0
TH2_k127_4479996_29	PFAM peptidase M22 glycoprotease	K14742	-	-	0.0000000000000000000000000000000000000000000000000000000000000001593	229.0
TH2_k127_4479996_3	ROK family	K00845,K13967,K19979,K20433	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	5.492e-207	653.0
TH2_k127_4479996_30	Threonylcarbamoyl adenosine biosynthesis protein TsaE	K06925	-	-	0.0000000000000000000000000000000000000000000000000000000000007703	215.0
TH2_k127_4479996_31	carboxylic acid catabolic process	-	-	-	0.0000000000000000000000000000000000000000000000000000000006676	212.0
TH2_k127_4479996_32	peptidase activity, acting on L-amino acid peptides	K20276,K21449	-	-	0.000000000000000000000000000000000000000000000000000000282	220.0
TH2_k127_4479996_33	Belongs to the RbsD FucU family	K02431	-	5.1.3.29	0.000000000000000000000000000000000000000000000000000001717	194.0
TH2_k127_4479996_35	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	-	-	-	0.000000000000000000000000000000000000000000000000005563	188.0
TH2_k127_4479996_36	Glyoxalase-like domain	K01759	-	4.4.1.5	0.0000000000000000000000000000000000000000000000001545	180.0
TH2_k127_4479996_37	Ferric uptake regulator family	K09825	-	-	0.000000000000000000000000000000000000000000003137	168.0
TH2_k127_4479996_38	WD40-like Beta Propeller Repeat	K03641	-	-	0.000000000000000000000000000000000000000000004121	180.0
TH2_k127_4479996_39	Uncharacterised protein, DegV family COG1307	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.000000000000000000000000000000000000001965	160.0
TH2_k127_4479996_4	PFAM UDP-glucose GDP-mannose dehydrogenase	K13015	-	1.1.1.136	1.562e-200	632.0
TH2_k127_4479996_40	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	K03789	-	2.3.1.128	0.000000000000000000000000000000001872	138.0
TH2_k127_4479996_41	EamA-like transporter family	-	-	-	0.000000000000000000000000000000002488	139.0
TH2_k127_4479996_42	PFAM MaoC domain protein dehydratase	K17865	-	4.2.1.55	0.000000000000000000000000000000004358	132.0
TH2_k127_4479996_43	PFAM FecR protein	K20276	-	-	0.0000000000000000000000000001639	135.0
TH2_k127_4479996_44	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	K08591	-	2.3.1.15	0.0000000000000000000000002465	113.0
TH2_k127_4479996_45	Helix-turn-helix domain	-	-	-	0.0000000000000000000000006002	109.0
TH2_k127_4479996_46	UTRA	K03710	-	-	0.000000000000000000108	94.0
TH2_k127_4479996_47	Parallel beta-helix repeats	-	-	-	0.0000000000000000008062	102.0
TH2_k127_4479996_48	self proteolysis	-	-	-	0.00000000000000001558	94.0
TH2_k127_4479996_49	TIGRFAM RHS repeat-associated core domain	-	-	-	0.00000000000000231	92.0
TH2_k127_4479996_5	Phosphofructokinase	K21071	-	2.7.1.11,2.7.1.90	4.275e-197	630.0
TH2_k127_4479996_50	Domain of unknown function (DUF333)	K14475	-	-	0.0000000000000339	85.0
TH2_k127_4479996_51	TIGRFAM esterase, PHB depolymerase family	-	-	-	0.00000000000003946	87.0
TH2_k127_4479996_52	pathogenesis	-	-	-	0.00000000000004763	87.0
TH2_k127_4479996_53	xylan catabolic process	K01179	-	3.2.1.4	0.0000000001546	75.0
TH2_k127_4479996_54	GntR family	K03710	-	-	0.000001866	52.0
TH2_k127_4479996_55	N-acetylglucosaminylinositol deacetylase activity	K01463	-	-	0.000007789	49.0
TH2_k127_4479996_56	Acetyltransferase (GNAT) domain	-	-	-	0.0003042	51.0
TH2_k127_4479996_57	MFS/sugar transport protein	-	-	-	0.0006382	49.0
TH2_k127_4479996_6	Glycosyltransferase like family 2	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013	579.0
TH2_k127_4479996_7	TIGRFAM cysteine desulfurase family protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377	535.0
TH2_k127_4479996_8	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	K01711	-	4.2.1.47	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971	505.0
TH2_k127_4479996_9	Cytidylyltransferase-like	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615	485.0
TH2_k127_4488917_0	Belongs to the ParA family	K03609	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592	375.0
TH2_k127_4488917_1	Belongs to the SEDS family	K05837	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062	347.0
TH2_k127_4488917_2	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	K03610	-	-	0.0000000000000000000000000000000000000000000000000000000008768	208.0
TH2_k127_4488917_3	PFAM penicillin-binding protein transpeptidase	K05515	-	3.4.16.4	0.00000000000000000000000000000000000000000000007316	177.0
TH2_k127_4488917_4	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	K03608	-	-	0.00000000000000000009273	92.0
TH2_k127_4527677_0	Lysine-2,3-aminomutase	K01843	-	5.4.3.2	7.04e-232	721.0
TH2_k127_4533035_0	Squalene--hopene cyclase	K17811	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576	5.5.1.16	0.00000000000000000000000000000000000000000000000000000000000000000000004029	248.0
TH2_k127_4533035_1	transferase activity, transferring alkyl or aryl (other than methyl) groups	K15911,K22313	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016101,GO:0016102,GO:0016114,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0035440,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0075136,GO:1901576	3.1.7.12,3.1.7.8,3.1.7.9	0.00000000000000000000000000000000000000000000000000000000000000000002239	246.0
TH2_k127_4533035_2	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	0.000000000008076	73.0
TH2_k127_4569337_0	-	-	-	-	0.0000000000000000000004138	102.0
TH2_k127_4569337_1	Cytochrome c554 and c-prime	-	-	-	0.0006514	50.0
TH2_k127_4573525_1	Putative esterase	K07214	-	-	0.00000000000000001097	93.0
TH2_k127_4573525_2	cyclopropane-fatty-acyl-phospholipid synthase	K00568	-	2.1.1.222,2.1.1.64	0.0000168	47.0
TH2_k127_4578457_0	Belongs to the glycosyl hydrolase 13 family	K01214	-	3.2.1.68	1.598e-235	735.0
TH2_k127_4578457_1	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	K00036	-	1.1.1.363,1.1.1.49	5.487e-233	728.0
TH2_k127_4578457_2	Belongs to the IlvD Edd family	K01690	GO:0003674,GO:0003824,GO:0004456,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019520,GO:0019521,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046177,GO:0046395,GO:0071704,GO:0072329,GO:1901575	4.2.1.12	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908	347.0
TH2_k127_4578457_3	TIGRFAM 6-phosphogluconolactonase	K01057	-	3.1.1.31	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817	326.0
TH2_k127_4584238_0	PFAM Exonuclease, RNase T and DNA polymerase III	K02342,K03722	-	2.7.7.7,3.6.4.12	0.0	1118.0
TH2_k127_4584238_1	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	K03702	-	-	0.0	1044.0
TH2_k127_4584238_10	iron ion homeostasis	K03322,K03709,K04758	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658	457.0
TH2_k127_4584238_11	Ferrous iron transport protein B	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909	435.0
TH2_k127_4584238_12	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929	416.0
TH2_k127_4584238_13	serine-type peptidase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076	398.0
TH2_k127_4584238_14	Iron-sulfur cluster-binding domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891	387.0
TH2_k127_4584238_15	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	K01007	-	2.7.9.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398	378.0
TH2_k127_4584238_16	S-adenosylmethionine-dependent methyltransferase	K06969	-	2.1.1.191	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545	364.0
TH2_k127_4584238_17	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	K03621	-	2.3.1.15	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147	363.0
TH2_k127_4584238_18	alpha/beta hydrolase fold	K01066	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444	347.0
TH2_k127_4584238_19	transcription factor binding	K11527	-	2.7.13.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444	316.0
TH2_k127_4584238_2	PFAM Enoyl-CoA hydratase isomerase	K07516	-	1.1.1.35	1.884e-247	788.0
TH2_k127_4584238_20	iron dependent repressor	K03709	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101	300.0
TH2_k127_4584238_21	histidine kinase A domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000001797	310.0
TH2_k127_4584238_22	Chromate resistance exported protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000001234	258.0
TH2_k127_4584238_23	arylsulfatase activity	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000001996	276.0
TH2_k127_4584238_24	Chlorophyllase enzyme	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000004229	267.0
TH2_k127_4584238_25	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000003403	248.0
TH2_k127_4584238_26	oxidoreductase activity	K00059	-	1.1.1.100	0.0000000000000000000000000000000000000000000000000000000000000006126	229.0
TH2_k127_4584238_27	D-ala D-ala ligase C-terminus	-	-	-	0.00000000000000000000000000000000000000000000000000000000000006849	227.0
TH2_k127_4584238_28	Putative TM nitroreductase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000717	217.0
TH2_k127_4584238_29	PFAM beta-lactamase domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000008231	226.0
TH2_k127_4584238_3	Ferrous iron transport protein B C terminus	K04759	-	-	1.076e-232	728.0
TH2_k127_4584238_30	Protein of unknown function DUF116	-	-	-	0.0000000000000000000000000000000000000000000000000000000004211	216.0
TH2_k127_4584238_31	channel protein, hemolysin III family	K11068	-	-	0.0000000000000000000000000000000000000000000000000000003534	200.0
TH2_k127_4584238_32	-	-	-	-	0.00000000000000000000000000000000000000000000000001168	188.0
TH2_k127_4584238_33	-	-	-	-	0.00000000000000000000000000000000000000000000000005625	186.0
TH2_k127_4584238_34	Domain of unknown function (DU1801)	-	-	-	0.0000000000000000000000000000000000000000005517	162.0
TH2_k127_4584238_35	-	-	-	-	0.000000000000000000000000000000000000000008419	167.0
TH2_k127_4584238_36	Bacterial regulatory proteins, tetR family	-	-	-	0.00000000000000000000000000000000003884	143.0
TH2_k127_4584238_37	ubiE/COQ5 methyltransferase family	-	-	-	0.0000000000000000000000000000000008769	139.0
TH2_k127_4584238_38	Bacterial regulatory proteins, tetR family	-	-	-	0.000000000000000000000000000000006443	134.0
TH2_k127_4584238_39	PFAM beta-lactamase domain protein	-	-	-	0.0000000000000000000000000000002325	132.0
TH2_k127_4584238_4	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	K00573	-	2.1.1.77	7.707e-203	654.0
TH2_k127_4584238_40	negative regulation of transcription, DNA-templated	-	-	-	0.000000000000000000000000000006098	122.0
TH2_k127_4584238_41	metal-dependent membrane protease	K07052	-	-	0.00000000000000000000000000006958	127.0
TH2_k127_4584238_42	-	-	-	-	0.0000000000000000000000000003639	120.0
TH2_k127_4584238_43	helix_turn_helix, Arsenical Resistance Operon Repressor	K21903	-	-	0.000000000000000000000000001001	117.0
TH2_k127_4584238_44	methyltransferase activity	-	-	-	0.000000000000000000000000002529	119.0
TH2_k127_4584238_45	Sucrose-6F-phosphate phosphohydrolase	K00696	-	2.4.1.14	0.000000000000000000000000003123	121.0
TH2_k127_4584238_46	gas vesicle protein	-	-	-	0.0000000000000000000000005046	109.0
TH2_k127_4584238_47	Protein of unknown function (DUF2812)	-	-	-	0.0000000000000000000000005188	111.0
TH2_k127_4584238_48	-	-	-	-	0.0000000000000000000000009432	119.0
TH2_k127_4584238_49	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	K00990	-	2.7.7.59	0.00000000000000000000006694	104.0
TH2_k127_4584238_5	PFAM Bile acid sodium symporter	K03325	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843	539.0
TH2_k127_4584238_50	Thioredoxin domain	-	-	-	0.000000000000000000007743	94.0
TH2_k127_4584238_51	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	K03076	-	-	0.000000000000000002558	93.0
TH2_k127_4584238_53	SCP-2 sterol transfer family	-	-	-	0.000000000000009548	79.0
TH2_k127_4584238_54	Domain of unknown function (DUF333)	K14475	-	-	0.00000000000002961	85.0
TH2_k127_4584238_55	Low molecular weight phosphatase family	K03741	-	1.20.4.1	0.00000000000104	70.0
TH2_k127_4584238_56	Protein of unknown function (DUF402)	-	-	-	0.00000009441	61.0
TH2_k127_4584238_58	-	-	-	-	0.000314	48.0
TH2_k127_4584238_6	Major Facilitator Superfamily	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944	533.0
TH2_k127_4584238_7	Belongs to the thiolase family	K00632	-	2.3.1.16	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752	496.0
TH2_k127_4584238_8	PFAM acyl-CoA dehydrogenase domain protein	K00249	-	1.3.8.7	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164	475.0
TH2_k127_4584238_9	PFAM permease	K07089	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142	466.0
TH2_k127_4593963_1	Belongs to the sigma-70 factor family. ECF subfamily	K03088	-	-	0.00000002863	58.0
TH2_k127_4600548_0	Diguanylate cyclase	-	-	-	0.0000000000000000000000000000000000000005865	159.0
TH2_k127_4600548_1	Globin	K05916	-	1.14.12.17	0.00002419	46.0
TH2_k127_4604106_0	PFAM multicopper oxidase type 2	-	-	-	0.0	1054.0
TH2_k127_4604106_1	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	K03737	-	1.2.7.1	4.532e-315	977.0
TH2_k127_4604106_10	Fatty acid desaturase	K10255	-	1.14.19.23,1.14.19.45	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956	409.0
TH2_k127_4604106_11	ATP-grasp domain	K14755	-	6.3.2.11	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659	355.0
TH2_k127_4604106_12	phosphate transport system permease protein	K02038	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982	332.0
TH2_k127_4604106_13	probably responsible for the translocation of the substrate across the membrane	K02037	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000817	327.0
TH2_k127_4604106_14	phosphate ion binding	K02040	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349	321.0
TH2_k127_4604106_15	response to heat	K07090	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001642	281.0
TH2_k127_4604106_16	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	K02036	-	3.6.3.27	0.00000000000000000000000000000000000000000000000000000000000000000000000000338	265.0
TH2_k127_4604106_17	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000003591	238.0
TH2_k127_4604106_18	methyltransferase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000004728	236.0
TH2_k127_4604106_19	Homocysteine S-methyltransferase	K00548	-	2.1.1.13	0.00000000000000000000000000000000000000000000000000000000000000004394	233.0
TH2_k127_4604106_2	Histidine kinase-like ATPases	-	-	-	1.011e-257	869.0
TH2_k127_4604106_20	FAD dependent oxidoreductase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000002551	234.0
TH2_k127_4604106_21	Uroporphyrinogen decarboxylase (URO-D)	K14080	-	2.1.1.246	0.000000000000000000000000000000000000000000000000000000001156	213.0
TH2_k127_4604106_22	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	-	0.00000000000000000000000000000000000000000000000000000001585	200.0
TH2_k127_4604106_23	GGDEF domain	-	-	-	0.00000000000000000000000000000000000000000000000009313	198.0
TH2_k127_4604106_24	Haloacid dehalogenase-like hydrolase	-	GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309	-	0.00000000000000000000000000000000000000000000001365	178.0
TH2_k127_4604106_25	PFAM NUDIX hydrolase	K01515	-	3.6.1.13	0.0000000000000000000000000000000000000000000008953	172.0
TH2_k127_4604106_26	Transcriptional regulator	-	-	-	0.000000000000000000000000000000000000000002244	160.0
TH2_k127_4604106_27	Transmembrane secretion effector	-	-	-	0.000000000000000000000000000000001779	148.0
TH2_k127_4604106_28	Pfam:DUF385	-	-	-	0.0000000000000000000000000000208	122.0
TH2_k127_4604106_29	methyltransferase activity	-	-	-	0.0000000000000000000008291	102.0
TH2_k127_4604106_3	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012	623.0
TH2_k127_4604106_30	LysM domain	K07273,K22278	-	3.5.1.104	0.0000000000000003421	88.0
TH2_k127_4604106_31	Histidine kinase	K20976	-	-	0.00000000000001282	81.0
TH2_k127_4604106_32	cobalamin binding	-	-	-	0.000000001291	64.0
TH2_k127_4604106_33	Bacterial regulatory proteins, crp family	K10914	-	-	0.00000000345	70.0
TH2_k127_4604106_34	STAS domain	K04749	-	-	0.00000001861	60.0
TH2_k127_4604106_35	Belongs to the anti-sigma-factor antagonist family	K04749,K06378	-	-	0.00000008084	65.0
TH2_k127_4604106_4	Sugar (and other) transporter	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326	602.0
TH2_k127_4604106_5	response to antibiotic	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938	577.0
TH2_k127_4604106_6	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	K03644	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144	524.0
TH2_k127_4604106_7	TIGRFAM flavoprotein, HI0933 family	K07007	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952	446.0
TH2_k127_4604106_8	NfeD-like C-terminal, partner-binding	K07403	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927	436.0
TH2_k127_4604106_9	Adenylyl cyclase class-3 4 guanylyl cyclase	K01768	-	4.6.1.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453	425.0
TH2_k127_4605217_0	His Kinase A (phosphoacceptor) domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572	623.0
TH2_k127_4605217_1	metallocarboxypeptidase activity	K05996	-	3.4.17.18	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592	538.0
TH2_k127_4605217_10	transferase activity, transferring alkyl or aryl (other than methyl) groups	K15911,K22313	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016101,GO:0016102,GO:0016114,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0035440,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0075136,GO:1901576	3.1.7.12,3.1.7.8,3.1.7.9	0.000000000000000000000000000000000000000000000000000000000000000006223	237.0
TH2_k127_4605217_11	PFAM Fibronectin type III domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000001587	228.0
TH2_k127_4605217_12	PFAM Response regulator receiver domain	K11624	-	-	0.0000000000000000000000000000000000000000000000000000000004727	209.0
TH2_k127_4605217_13	N-terminal 7TM region of histidine kinase	K07673	-	2.7.13.3	0.0000000000000000000000000000000000000000000000000000004125	214.0
TH2_k127_4605217_14	transmembrane transporter activity	K05820	-	-	0.0000000000000000000000000000000000000000000000000000008135	210.0
TH2_k127_4605217_15	-	-	-	-	0.000000000000000000000000000000000000000000000000000006361	193.0
TH2_k127_4605217_16	Peptidase family M28	-	-	-	0.00000000000000000000000000000000000000000000000000004246	201.0
TH2_k127_4605217_17	histidine kinase A domain protein	-	-	-	0.0000000000000000000000000000000000000000000000003665	196.0
TH2_k127_4605217_18	Domain of unknown function (DUF296)	K06934	-	-	0.00000000000000000000000000000000000001257	148.0
TH2_k127_4605217_19	phosphorelay sensor kinase activity	K16923	-	-	0.00000000000000000000000000000000000004916	151.0
TH2_k127_4605217_2	PFAM helix-turn-helix domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166	511.0
TH2_k127_4605217_20	cheY-homologous receiver domain	-	-	-	0.00000000000000000000000000000000000006687	145.0
TH2_k127_4605217_21	Nucleoside H+ symporter	K05820	-	-	0.00000000000000000001053	106.0
TH2_k127_4605217_23	cheY-homologous receiver domain	-	-	-	0.00000000005103	68.0
TH2_k127_4605217_24	part of an ABC transporter complex. Responsible for energy coupling to the transport system	K02006,K16787	-	-	0.00000000006104	66.0
TH2_k127_4605217_25	Peptidogalycan biosysnthesis/recognition	K00652	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.47	0.000001104	61.0
TH2_k127_4605217_26	Psort location CytoplasmicMembrane, score 10.00	K16923	-	-	0.0003485	46.0
TH2_k127_4605217_3	Squalene--hopene cyclase	K17811	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576	5.5.1.16	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525	425.0
TH2_k127_4605217_4	PFAM Inosine uridine-preferring nucleoside hydrolase	K01239	-	3.2.2.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766	332.0
TH2_k127_4605217_5	GGDEF domain	K07315	-	3.1.3.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186	319.0
TH2_k127_4605217_6	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	K00852	-	2.7.1.15	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086	301.0
TH2_k127_4605217_7	energy transducer activity	K03531,K03832	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422	308.0
TH2_k127_4605217_9	spore germination	K03298	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000002386	255.0
TH2_k127_4627649_0	Bacterial regulatory proteins, tetR family	-	-	-	0.00000000000000000000000000000000000003575	151.0
TH2_k127_4627649_1	pyruvate phosphate dikinase, PEP	K01007	-	2.7.9.2	0.000000000000000000000000000003298	126.0
TH2_k127_4627649_2	-	-	-	-	0.0000000000000000000000000003887	118.0
TH2_k127_4627649_3	Fibronectin type 3 domain	K20276	-	-	0.0000000000000000001354	95.0
TH2_k127_4627649_4	metal-dependent membrane protease	K07052	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0071944,GO:0080120,GO:0140096,GO:1901564	-	0.0000000000000000001815	100.0
TH2_k127_4627649_5	sequence-specific DNA binding	-	-	-	0.00001949	49.0
TH2_k127_4633265_0	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	K01537	-	3.6.3.8	0.0	1140.0
TH2_k127_4633265_1	PFAM glycosyl transferase, family 51	-	-	-	0.0	1133.0
TH2_k127_4633265_10	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	K00937	-	2.7.4.1	7.216e-254	803.0
TH2_k127_4633265_100	nucleotidyltransferase activity	-	-	-	0.00000000000000009718	83.0
TH2_k127_4633265_101	transferase activity, transferring acyl groups	K15520	-	2.3.1.189	0.0000000000000005399	82.0
TH2_k127_4633265_102	Integral membrane protein TerC family	K05794	-	-	0.000000000000003755	78.0
TH2_k127_4633265_103	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	K03536	-	3.1.26.5	0.00000000000001597	78.0
TH2_k127_4633265_104	DNA-binding transcription factor activity	-	-	-	0.00000000000003973	78.0
TH2_k127_4633265_105	Sulfatase-modifying factor enzyme 1	-	-	-	0.0000000000001128	76.0
TH2_k127_4633265_106	nucleotidyltransferase activity	-	-	-	0.0000000000001318	72.0
TH2_k127_4633265_108	4-vinyl reductase, 4VR	K07013,K17763	-	-	0.000000008008	64.0
TH2_k127_4633265_11	Amino acid permease	-	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	1.613e-240	759.0
TH2_k127_4633265_110	-	-	-	-	0.00000004023	61.0
TH2_k127_4633265_111	Integral membrane protein TerC family	K05794	-	-	0.00000004086	57.0
TH2_k127_4633265_113	-	-	-	-	0.000001197	60.0
TH2_k127_4633265_114	Phosphotransferase enzyme family	-	-	-	0.00006785	48.0
TH2_k127_4633265_115	aminopeptidase activity	-	-	-	0.00008558	47.0
TH2_k127_4633265_116	transferase activity, transferring acyl groups	K15520	-	2.3.1.189	0.0002096	46.0
TH2_k127_4633265_117	Putative zinc-finger	-	-	-	0.0003659	50.0
TH2_k127_4633265_12	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	4.054e-212	698.0
TH2_k127_4633265_13	-	K07138	-	-	2.31e-202	636.0
TH2_k127_4633265_14	WD-40 repeat	-	-	-	1.814e-201	686.0
TH2_k127_4633265_15	metal-dependent phosphohydrolase, HD sub domain	K07037	-	-	2.442e-199	642.0
TH2_k127_4633265_16	PFAM type II secretion system protein E	K02283	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945	607.0
TH2_k127_4633265_17	PFAM Amidohydrolase 3	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325	582.0
TH2_k127_4633265_18	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	K00975	-	2.7.7.27	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522	576.0
TH2_k127_4633265_19	Flavin containing amine oxidoreductase	K09516	-	1.3.99.23	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917	516.0
TH2_k127_4633265_2	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	K01868	-	6.1.1.3	4.749e-302	935.0
TH2_k127_4633265_20	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	K03215	-	2.1.1.190	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016	473.0
TH2_k127_4633265_21	aminotransferase class I and II	K10907	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528	463.0
TH2_k127_4633265_23	PFAM aminotransferase class V	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641	407.0
TH2_k127_4633265_24	Two component transcriptional regulator, winged helix family	K07667,K07668	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885	394.0
TH2_k127_4633265_25	PFAM von Willebrand factor type A	K07114	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671	404.0
TH2_k127_4633265_26	PFAM ATP-binding region, ATPase domain protein	K07636	-	2.7.13.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865	394.0
TH2_k127_4633265_27	deoxyribonuclease IV (phage-T4-induced) activity	K01151	-	3.1.21.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186	383.0
TH2_k127_4633265_28	Encoded by	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548	398.0
TH2_k127_4633265_29	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627	385.0
TH2_k127_4633265_3	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	K03655	-	3.6.4.12	3.715e-289	912.0
TH2_k127_4633265_30	PFAM Nucleotidyl transferase	K00973	-	2.7.7.24	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218	367.0
TH2_k127_4633265_31	Two component transcriptional regulator, LuxR family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112	354.0
TH2_k127_4633265_32	PFAM Cobyrinic acid a,c-diamide synthase	K03496	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655	350.0
TH2_k127_4633265_33	Uncharacterised ACR (DUF711)	K09157	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342	357.0
TH2_k127_4633265_34	PhoQ Sensor	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897	351.0
TH2_k127_4633265_35	PFAM alpha beta hydrolase fold	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391	346.0
TH2_k127_4633265_36	Transcriptional regulatory protein, C terminal	K07667	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694	334.0
TH2_k127_4633265_37	PFAM peptidase C60, sortase A and B	K07284	-	3.4.22.70	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795	335.0
TH2_k127_4633265_38	SMART protein phosphatase 2C domain protein	K20074	-	3.1.3.16	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648	325.0
TH2_k127_4633265_39	Two component transcriptional regulator, winged helix family	K02483	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087	315.0
TH2_k127_4633265_4	ABC transporter, transmembrane region	K06147	-	-	4.151e-287	893.0
TH2_k127_4633265_40	PFAM Biotin lipoate A B protein ligase	K03800	-	6.3.1.20	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561	314.0
TH2_k127_4633265_41	PFAM PfkB domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803	306.0
TH2_k127_4633265_42	PFAM ATP-binding region, ATPase domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199	323.0
TH2_k127_4633265_43	PFAM Glycosyl transferase family 2	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000473	295.0
TH2_k127_4633265_44	Belongs to the ParB family	K03497	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000008362	275.0
TH2_k127_4633265_45	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	K03437	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000002234	273.0
TH2_k127_4633265_46	TrkA-C domain	K03499	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000003507	271.0
TH2_k127_4633265_47	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000002918	270.0
TH2_k127_4633265_48	-	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000111	258.0
TH2_k127_4633265_49	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	K02520	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000001215	258.0
TH2_k127_4633265_5	Amino acid permease	-	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	2.442e-283	883.0
TH2_k127_4633265_50	PFAM basic membrane lipoprotein	K07335	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000001479	291.0
TH2_k127_4633265_51	PFAM 60 kDa inner membrane insertion protein	K03217	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000031	258.0
TH2_k127_4633265_52	DNA binding	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000003539	256.0
TH2_k127_4633265_53	TrkA-N domain	K03499,K10716	-	-	0.00000000000000000000000000000000000000000000000000000000000000000001062	239.0
TH2_k127_4633265_54	Hydrolase, alpha beta domain protein	K01048	-	3.1.1.5	0.0000000000000000000000000000000000000000000000000000000000000000008396	239.0
TH2_k127_4633265_55	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	K00954	-	2.7.7.3	0.0000000000000000000000000000000000000000000000000000000000000000009615	232.0
TH2_k127_4633265_56	Serine threonine protein kinase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000008285	242.0
TH2_k127_4633265_57	Phosphotransferase enzyme family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000003267	223.0
TH2_k127_4633265_58	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	K03470	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	0.0000000000000000000000000000000000000000000000000000000000005286	217.0
TH2_k127_4633265_59	PFAM single-stranded nucleic acid binding R3H domain protein	K06346	-	-	0.00000000000000000000000000000000000000000000000000000000001238	216.0
TH2_k127_4633265_6	Serine threonine protein kinase	K12132	-	2.7.11.1	5.796e-278	869.0
TH2_k127_4633265_60	Caspase domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000005283	215.0
TH2_k127_4633265_61	-	-	-	-	0.00000000000000000000000000000000000000000000000000001955	204.0
TH2_k127_4633265_62	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	0.000000000000000000000000000000000000000000000000002647	186.0
TH2_k127_4633265_63	Metalloenzyme superfamily	-	-	-	0.00000000000000000000000000000000000000000000000002812	191.0
TH2_k127_4633265_64	Calcineurin-like phosphoesterase	-	-	-	0.000000000000000000000000000000000000000000000000238	183.0
TH2_k127_4633265_65	PFAM Appr-1-p processing domain protein	-	-	-	0.0000000000000000000000000000000000000000000000006769	180.0
TH2_k127_4633265_66	Histidine kinase A domain protein	-	-	-	0.00000000000000000000000000000000000000000000001857	183.0
TH2_k127_4633265_67	Belongs to the DapA family	K01714	-	4.3.3.7	0.00000000000000000000000000000000000000000000001861	184.0
TH2_k127_4633265_68	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	K02887	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	0.0000000000000000000000000000000000000000000000459	171.0
TH2_k127_4633265_69	PFAM Forkhead-associated protein	-	-	-	0.0000000000000000000000000000000000000000000003671	172.0
TH2_k127_4633265_7	stress-induced mitochondrial fusion	-	-	-	8e-268	839.0
TH2_k127_4633265_70	PFAM GCN5-related N-acetyltransferase	-	-	-	0.0000000000000000000000000000000000000000000005876	177.0
TH2_k127_4633265_71	sequence-specific DNA binding	-	-	-	0.0000000000000000000000000000000000000000000209	169.0
TH2_k127_4633265_72	GGDEF domain	K13069	-	2.7.7.65	0.0000000000000000000000000000000000000000003037	172.0
TH2_k127_4633265_73	MaoC like domain	-	-	-	0.0000000000000000000000000000000000000000004249	162.0
TH2_k127_4633265_74	Peptidase family M28	-	-	-	0.000000000000000000000000000000000000000001028	169.0
TH2_k127_4633265_75	Could be involved in insertion of integral membrane proteins into the membrane	K08998	-	-	0.000000000000000000000000000000000000000001877	156.0
TH2_k127_4633265_76	PFAM diacylglycerol kinase	K00901	-	2.7.1.107	0.000000000000000000000000000000000000000005131	158.0
TH2_k127_4633265_77	PFAM CHAD domain containing protein	K08296	-	-	0.00000000000000000000000000000000000000001344	164.0
TH2_k127_4633265_78	organic phosphonate transport	K02044	-	-	0.0000000000000000000000000000000000000002586	167.0
TH2_k127_4633265_79	WD40-like Beta Propeller Repeat	-	-	-	0.000000000000000000000000000000000000001945	167.0
TH2_k127_4633265_8	protein histidine kinase activity	K02484,K07636,K07642	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	2.512e-267	859.0
TH2_k127_4633265_80	Belongs to the small heat shock protein (HSP20) family	K13993	-	-	0.000000000000000000000000000000000000002001	151.0
TH2_k127_4633265_81	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	0.00000000000000000000000000000000000001101	160.0
TH2_k127_4633265_82	4-vinyl reductase, 4VR	-	-	-	0.0000000000000000000000000000000000008618	146.0
TH2_k127_4633265_83	ECF sigma factor	K03088	-	-	0.00000000000000000000000000000000002179	143.0
TH2_k127_4633265_84	Protein of unknown function (DUF4230)	-	-	-	0.0000000000000000000000000000000006399	139.0
TH2_k127_4633265_85	Psort location CytoplasmicMembrane, score	-	-	-	0.000000000000000000000000000000007702	146.0
TH2_k127_4633265_86	AAA domain	-	-	-	0.0000000000000000000000000000003171	130.0
TH2_k127_4633265_87	Glutamyl-tRNA amidotransferase	K09117	-	-	0.000000000000000000000000000002072	126.0
TH2_k127_4633265_88	Transposase DDE domain	-	-	-	0.000000000000000000000000000003395	121.0
TH2_k127_4633265_89	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	K07042	-	-	0.000000000000000000000000000005003	124.0
TH2_k127_4633265_9	ABC transporter	K06147	-	-	9.42e-259	818.0
TH2_k127_4633265_90	peptidyl-tyrosine sulfation	-	-	-	0.00000000000000000000000000000554	125.0
TH2_k127_4633265_91	Phosphoglycerate mutase family	K08296	-	-	0.000000000000000000000000006335	117.0
TH2_k127_4633265_92	Cold shock	K03704	-	-	0.000000000000000000000000006809	110.0
TH2_k127_4633265_93	Belongs to the bacterial ribosomal protein bL35 family	K02916	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.00000000000000000000000227	104.0
TH2_k127_4633265_94	Uncharacterized conserved protein (DUF2196)	-	-	-	0.00000000000000000000000368	102.0
TH2_k127_4633265_95	PQQ enzyme repeat	-	-	-	0.000000000000000000000004227	115.0
TH2_k127_4633265_96	-	-	-	-	0.00000000000000000000001706	101.0
TH2_k127_4633265_97	-	-	-	-	0.000000000000000000002191	100.0
TH2_k127_4633265_98	-	-	-	-	0.0000000000000000008849	89.0
TH2_k127_4633265_99	Ribosomal protein L34	K02914	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.000000000000000001726	86.0
TH2_k127_4676001_0	Belongs to the Nudix hydrolase family	-	-	-	0.00000000000000000000000000007104	122.0
TH2_k127_4676001_1	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	0.000000000000000615	80.0
TH2_k127_4689402_0	Peptidase family M28	-	-	-	0.00000000000000000000000000003869	128.0
TH2_k127_4689402_1	aminopeptidase activity	-	-	-	0.0000000000000001097	85.0
TH2_k127_4689402_2	TIR domain	-	-	-	0.000001669	53.0
TH2_k127_4689402_3	PFAM NHL repeat containing protein	-	-	-	0.000001769	60.0
TH2_k127_4806124_0	aldehyde dehydrogenase (NAD) activity	K00128	-	1.2.1.3	0.0	1077.0
TH2_k127_4806124_1	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	K00962	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	1.995e-311	970.0
TH2_k127_4806124_10	Alpha-amylase domain	K01208	-	3.2.1.133,3.2.1.135,3.2.1.54	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204	514.0
TH2_k127_4806124_11	PFAM alpha amylase, catalytic	K01208	-	3.2.1.133,3.2.1.135,3.2.1.54	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019	508.0
TH2_k127_4806124_12	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	K00124,K00335,K18005	-	1.12.1.2,1.6.5.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887	511.0
TH2_k127_4806124_13	peptidase dimerisation domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382	501.0
TH2_k127_4806124_14	PFAM Alpha amylase, catalytic	K01176,K01208	GO:0000272,GO:0000287,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016020,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0019867,GO:0030246,GO:0030247,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046872,GO:0071704,GO:1901575,GO:2001070	3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555	497.0
TH2_k127_4806124_15	Pyruvate phosphate dikinase, PEP pyruvate binding	K01006,K01007	-	2.7.9.1,2.7.9.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481	462.0
TH2_k127_4806124_16	PFAM ROK family protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409	451.0
TH2_k127_4806124_17	Polyphosphate kinase 2 (PPK2)	K22468	-	2.7.4.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413	445.0
TH2_k127_4806124_18	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	K01619	-	4.1.2.4	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719	442.0
TH2_k127_4806124_19	Catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P	K00965	-	2.7.7.12	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428	432.0
TH2_k127_4806124_2	FAD linked oxidases, C-terminal domain	K18930	-	-	1.554e-300	949.0
TH2_k127_4806124_20	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068	415.0
TH2_k127_4806124_21	PFAM binding-protein-dependent transport systems inner membrane component	K15772	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746	397.0
TH2_k127_4806124_22	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732	389.0
TH2_k127_4806124_23	Alanine racemase, N-terminal domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319	350.0
TH2_k127_4806124_24	formate dehydrogenase (NAD+) activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113	327.0
TH2_k127_4806124_25	histidine kinase A domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455	335.0
TH2_k127_4806124_26	Inosine-uridine preferring nucleoside hydrolase	K01239	-	3.2.2.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817	313.0
TH2_k127_4806124_27	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	K12410	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486	302.0
TH2_k127_4806124_28	hydrolase activity, acting on ester bonds	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236	298.0
TH2_k127_4806124_29	DNA polymerase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004098	292.0
TH2_k127_4806124_3	PFAM molybdopterin oxidoreductase	K00123,K05299	-	1.17.1.10,1.17.1.9	3.613e-212	683.0
TH2_k127_4806124_30	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000005124	253.0
TH2_k127_4806124_31	-	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000001854	241.0
TH2_k127_4806124_32	EamA-like transporter family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000481	232.0
TH2_k127_4806124_33	Deacylase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000004013	228.0
TH2_k127_4806124_34	LURP-one-related	-	-	-	0.0000000000000000000000000000000000000000000000000000000000006232	214.0
TH2_k127_4806124_35	protein deglycation	K03152,K05520,K12132	-	2.7.11.1,3.5.1.124	0.00000000000000000000000000000000000000000000000000000000007284	213.0
TH2_k127_4806124_36	ABC-2 family transporter protein	K01992	-	-	0.000000000000000000000000000000000000000000000000000000009305	207.0
TH2_k127_4806124_37	ABC-2 family transporter protein	K01992	-	-	0.000000000000000000000000000000000000000000000000000005306	211.0
TH2_k127_4806124_38	Uncharacterized protein family UPF0029	K00560,K01271	-	2.1.1.45,3.4.13.9	0.000000000000000000000000000000000000000000000000000005666	196.0
TH2_k127_4806124_39	Molybdopterin oxidoreductase Fe4S4 region	K00336,K05299	-	1.17.1.10,1.6.5.3	0.0000000000000000000000000000000000000000000000003988	179.0
TH2_k127_4806124_4	MFS/sugar transport protein	K03292	-	-	1.237e-204	644.0
TH2_k127_4806124_40	Transglutaminase-like superfamily	-	-	-	0.00000000000000000000000000000000000000000000001476	179.0
TH2_k127_4806124_41	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	0.0000000000000000000000000000000000000000000008015	170.0
TH2_k127_4806124_42	COG0500 SAM-dependent methyltransferases	-	-	-	0.000000000000000000000000000000000000000000005738	170.0
TH2_k127_4806124_43	iron dependent repressor	-	-	-	0.0000000000000000000000000000000000000001368	154.0
TH2_k127_4806124_44	Beta-L-arabinofuranosidase, GH127	-	-	-	0.000000000000000000000000000000000001497	143.0
TH2_k127_4806124_45	-	-	-	-	0.000000000000000000000000000000003985	136.0
TH2_k127_4806124_46	-	-	-	-	0.000000000000000000000000000000006089	135.0
TH2_k127_4806124_47	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	K02956	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.0000000000000000000000000000003169	124.0
TH2_k127_4806124_48	Involved in the TonB-independent uptake of proteins	K03641	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	0.000000000000000000000000000008928	131.0
TH2_k127_4806124_49	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	0.00000000000000000000000000008178	119.0
TH2_k127_4806124_5	NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	K00336,K05299	-	1.17.1.10,1.6.5.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478	615.0
TH2_k127_4806124_50	-	-	-	-	0.00000000000000000000000172	110.0
TH2_k127_4806124_51	acetyltransferase	-	-	-	0.00000000000000000000176	99.0
TH2_k127_4806124_52	uridine kinase	-	-	-	0.00000000000000001626	91.0
TH2_k127_4806124_53	Helix-turn-helix XRE-family like proteins	K21498	-	-	0.0000000000000001471	81.0
TH2_k127_4806124_54	YCII-related domain	-	-	-	0.00000000000000251	80.0
TH2_k127_4806124_56	cheY-homologous receiver domain	-	-	-	0.00000002522	59.0
TH2_k127_4806124_57	KR domain	K07124	-	-	0.00000006543	57.0
TH2_k127_4806124_58	KR domain	K07124	-	-	0.0000001625	56.0
TH2_k127_4806124_59	PFAM Major Facilitator Superfamily	-	-	-	0.0000007305	54.0
TH2_k127_4806124_6	PFAM aminotransferase class V	K01634	-	4.1.2.27	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437	595.0
TH2_k127_4806124_60	short-chain dehydrogenase	K07124	-	-	0.000002709	52.0
TH2_k127_4806124_61	-	-	-	-	0.00001549	60.0
TH2_k127_4806124_62	Protein of unknown function (DUF3592)	-	-	-	0.00004708	53.0
TH2_k127_4806124_63	iron dependent repressor	-	-	-	0.00007671	46.0
TH2_k127_4806124_64	Acetyltransferase (GNAT) domain	-	-	-	0.0001348	45.0
TH2_k127_4806124_65	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	K03826,K03827	-	-	0.0001742	47.0
TH2_k127_4806124_66	Serine threonine protein kinase	-	-	-	0.0001816	53.0
TH2_k127_4806124_67	Transposase	-	-	-	0.000368	49.0
TH2_k127_4806124_68	Psort location Cytoplasmic, score 8.87	-	-	-	0.0003777	48.0
TH2_k127_4806124_69	Protease prsW family	-	-	-	0.0004341	52.0
TH2_k127_4806124_7	Amidase	K01426	-	3.5.1.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008326	571.0
TH2_k127_4806124_70	DNA segregation ATPase FtsK SpoIIIE and related	K03466	-	-	0.0006514	50.0
TH2_k127_4806124_8	maltose binding	K15770,K15771	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372	518.0
TH2_k127_4806124_9	transmembrane transport	K15771	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665	507.0
TH2_k127_483332_0	PFAM alpha-2-macroglobulin domain protein	K06894	-	-	0.0	1147.0
TH2_k127_483332_1	Molybdopterin oxidoreductase Fe4S4 domain	K00123	-	1.17.1.9	2.735e-293	920.0
TH2_k127_483332_10	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000284	246.0
TH2_k127_483332_11	4Fe-4S dicluster domain	K12143	-	-	0.0000000000000000000000000000000000000000000000000000000000002626	216.0
TH2_k127_483332_12	4Fe-4S dicluster domain	K12136	-	-	0.000000000000000000000000000000000000000000000000000007955	196.0
TH2_k127_483332_13	2 iron, 2 sulfur cluster binding	K00334	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	0.000000000000000000000000000000000000000000000000002424	186.0
TH2_k127_483332_14	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	0.000000000000000000000000000000000000000000000000002631	195.0
TH2_k127_483332_15	Toxic component of a toxin-antitoxin (TA) module	K07171	-	-	0.00000000000000000000000000000000000000000000000001238	181.0
TH2_k127_483332_16	Hydrogenase maturation protease	K08315	-	3.4.23.51	0.000000000000000000000000000000000000000000000003407	178.0
TH2_k127_483332_17	dehydrogenase reductase family 9C member 7	K00019,K11154,K13369	GO:0003674,GO:0003824,GO:0004745,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0055114,GO:0070013	1.1.1.105,1.1.1.239,1.1.1.30,1.1.1.62	0.000000000000000000000000000000000000000000007042	179.0
TH2_k127_483332_18	formate hydrogenlyase maturation	K12145,K15834	-	-	0.00000000000000000000000000000000000000009638	154.0
TH2_k127_483332_19	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	K01712	-	4.2.1.49	0.000000000000000000000000000000000000008512	149.0
TH2_k127_483332_2	Nickel-dependent hydrogenase	K15830	-	-	4.614e-281	872.0
TH2_k127_483332_20	Ferredoxin	K00335,K17992	-	1.12.1.3,1.6.5.3	0.000000000000000000000000000001912	126.0
TH2_k127_483332_21	Transposase DDE domain	-	-	-	0.0000000000001574	75.0
TH2_k127_483332_22	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	K01712	-	4.2.1.49	0.00000000004998	64.0
TH2_k127_483332_23	CAAX amino terminal protease family protein	K07052	-	-	0.00000005813	64.0
TH2_k127_483332_24	PFAM transposase mutator type	-	-	-	0.0002896	45.0
TH2_k127_483332_3	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	K00335,K05587	-	1.6.5.3	1.533e-244	765.0
TH2_k127_483332_4	NADH Ubiquinone plastoquinone (Complex I)	K00342,K05568,K12137	-	1.6.5.3	1.226e-203	655.0
TH2_k127_483332_5	PFAM NADH Ubiquinone plastoquinone	K12141	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939	584.0
TH2_k127_483332_6	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	K12139	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039	582.0
TH2_k127_483332_7	NADH dehydrogenase	K12138	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086	366.0
TH2_k127_483332_8	NADH ubiquinone oxidoreductase, 20 Kd subunit	K12144,K14088,K15832	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631	364.0
TH2_k127_483332_9	Transcriptional regulatory protein, C terminal	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000271	280.0
TH2_k127_4845347_0	PfkB domain protein	K00874	-	2.7.1.45	1.793e-199	626.0
TH2_k127_4845347_1	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	K00033	-	1.1.1.343,1.1.1.44	7.462e-199	629.0
TH2_k127_4845347_2	lactate racemase activity	K22373	-	5.1.2.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592	330.0
TH2_k127_4845347_3	Dehydrogenase	-	-	-	0.000000000000000005008	85.0
TH2_k127_4863626_0	ATPases associated with a variety of cellular activities	K10441	-	3.6.3.17	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965	521.0
TH2_k127_4863626_1	Belongs to the binding-protein-dependent transport system permease family	K10440	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491	511.0
TH2_k127_4863626_2	alpha/beta hydrolase fold	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138	312.0
TH2_k127_4863626_3	alpha/beta hydrolase fold	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000001794	231.0
TH2_k127_4885218_0	Allophanate hydrolase subunit 1	-	-	-	0.0000000000000000000000000000000000000000000000000000004475	198.0
TH2_k127_4885218_1	DNA-templated transcription, initiation	K03088	-	-	0.000000000000000000000000000000003797	138.0
TH2_k127_4885218_2	Putative zinc-finger	-	-	-	0.00008184	52.0
TH2_k127_4892082_0	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	K11618	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004148	290.0
TH2_k127_4892082_1	Histidine kinase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000007686	244.0
TH2_k127_4892082_2	Ribosomal RNA adenine dimethylase	-	-	-	0.0000000000000001327	85.0
TH2_k127_4892103_0	Adenylyl cyclase class-3 4 guanylyl cyclase	K01768	-	4.6.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756	427.0
TH2_k127_4892103_1	Histidine kinase-like ATPases	-	-	-	0.0000000000000000000000000000000000000000000000000000000002399	206.0
TH2_k127_4892103_2	LysM domain	K07273,K22278	-	3.5.1.104	0.0000000000000000005292	96.0
TH2_k127_4892103_3	NUDIX domain	K01515	-	3.6.1.13	0.0000000000000000058	89.0
TH2_k127_4892103_4	Histidine kinase A domain protein	-	-	-	0.00000000000000004499	86.0
TH2_k127_4985710_0	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191	341.0
TH2_k127_4985710_1	Zinc-binding dehydrogenase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000001344	240.0
TH2_k127_5000629_0	histidine kinase A domain protein	-	-	-	0.0	1178.0
TH2_k127_5000629_1	Belongs to the UPF0441 family	-	-	-	0.0	1096.0
TH2_k127_5000629_10	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	K00789	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339	582.0
TH2_k127_5000629_100	acetyltransferase	K03789	-	2.3.1.128	0.000000000000000000000000000000000005064	141.0
TH2_k127_5000629_101	Membrane	-	-	-	0.000000000000000000000000000000000009532	152.0
TH2_k127_5000629_102	Histidine kinase-like ATPases	-	-	-	0.0000000000000000000000000000000000107	159.0
TH2_k127_5000629_103	-O-antigen	-	-	-	0.00000000000000000000000000000000001073	153.0
TH2_k127_5000629_104	chromosome segregation	K03497	-	-	0.00000000000000000000000000000000005025	144.0
TH2_k127_5000629_106	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	K07025,K20866	-	3.1.3.10	0.000000000000000000000000000000000181	140.0
TH2_k127_5000629_107	Scavenger mRNA decapping enzyme C-term binding	K02503	-	-	0.0000000000000000000000000000000002999	137.0
TH2_k127_5000629_108	EAL domain	-	-	-	0.00000000000000000000000000000002876	147.0
TH2_k127_5000629_109	Sulfotransferase domain	-	-	-	0.00000000000000000000000000000004986	137.0
TH2_k127_5000629_11	protein methyltransferase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189	550.0
TH2_k127_5000629_110	PFAM Short-chain dehydrogenase reductase SDR	K00059	-	1.1.1.100	0.0000000000000000000000000000003285	130.0
TH2_k127_5000629_112	Acetyltransferase (GNAT) domain	-	-	-	0.000000000000000000000000000003836	126.0
TH2_k127_5000629_113	Acetyltransferase (GNAT) domain	-	-	-	0.000000000000000000000000000007281	128.0
TH2_k127_5000629_114	YacP-like NYN domain	K06962	-	-	0.00000000000000000000000000008282	121.0
TH2_k127_5000629_115	PFAM regulatory protein, MerR	-	-	-	0.0000000000000000000000000001812	122.0
TH2_k127_5000629_116	-	-	-	-	0.000000000000000000000001531	109.0
TH2_k127_5000629_117	Ig-like domain from next to BRCA1 gene	-	-	-	0.00000000000000000000000963	108.0
TH2_k127_5000629_118	Ig-like domain from next to BRCA1 gene	-	-	-	0.0000000000000000000001068	107.0
TH2_k127_5000629_119	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	0.0000000000000000000005702	99.0
TH2_k127_5000629_12	Major facilitator Superfamily	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855	541.0
TH2_k127_5000629_120	proteolysis	K21140	-	3.13.1.6	0.000000000000000000001009	100.0
TH2_k127_5000629_121	ABC transporter substrate-binding protein PnrA-like	K02058,K05519,K07335	-	-	0.000000000000000000017	103.0
TH2_k127_5000629_123	Ig-like domain from next to BRCA1 gene	-	-	-	0.00000000000000000009194	100.0
TH2_k127_5000629_124	Belongs to the small heat shock protein (HSP20) family	K13993	-	-	0.0000000000000000003711	92.0
TH2_k127_5000629_125	Transposase DDE domain	-	-	-	0.0000000000000000007326	90.0
TH2_k127_5000629_126	Involved in the tonB-independent uptake of proteins	K03641	-	-	0.00000000000000000702	96.0
TH2_k127_5000629_127	Protein of unknown function (DUF1565)	-	-	-	0.00000000000000002124	99.0
TH2_k127_5000629_128	-	-	-	-	0.0000000000000000724	90.0
TH2_k127_5000629_129	Sporulation and spore germination	-	-	-	0.000000000000001903	91.0
TH2_k127_5000629_13	flavoprotein, PP_4765 family	K07007	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507	532.0
TH2_k127_5000629_130	-	-	-	-	0.000000000000002414	86.0
TH2_k127_5000629_131	Zinc finger domain	-	-	-	0.00000000000002207	85.0
TH2_k127_5000629_132	Transposase IS66 family	-	-	-	0.00000000000004479	74.0
TH2_k127_5000629_133	Sporulation and spore germination	-	-	-	0.0000000000002768	84.0
TH2_k127_5000629_135	TIGRFAM esterase, PHB depolymerase family	-	-	-	0.000000000006548	81.0
TH2_k127_5000629_136	-	-	-	-	0.000000000008388	69.0
TH2_k127_5000629_137	YcxB-like protein	-	-	-	0.00000000002106	71.0
TH2_k127_5000629_138	regulation of cell shape	-	-	-	0.00000000002922	67.0
TH2_k127_5000629_139	peptidase	K21471	-	-	0.00000000005294	76.0
TH2_k127_5000629_14	WD40 domain protein beta Propeller	K03641	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431	509.0
TH2_k127_5000629_140	-	-	-	-	0.0000000003752	66.0
TH2_k127_5000629_141	-	-	-	-	0.000000000435	66.0
TH2_k127_5000629_142	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	0.000000007697	63.0
TH2_k127_5000629_143	PFAM GCN5-related N-acetyltransferase	-	-	-	0.00000001153	59.0
TH2_k127_5000629_144	F420H(2)-dependent quinone reductase	-	-	-	0.0000000294	63.0
TH2_k127_5000629_145	PFAM SMP-30 Gluconolaconase	-	-	-	0.0000001694	56.0
TH2_k127_5000629_146	Transposase IS66 family	-	-	-	0.000001046	54.0
TH2_k127_5000629_148	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	0.00004911	54.0
TH2_k127_5000629_149	Protein of unknown function (DUF1232)	-	-	-	0.00009791	50.0
TH2_k127_5000629_15	PFAM extracellular solute-binding protein family 1	K02027	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809	490.0
TH2_k127_5000629_150	Transposase DDE domain	-	-	-	0.0002544	44.0
TH2_k127_5000629_151	sh3 domain protein	K01448,K04771	-	3.4.21.107,3.5.1.28	0.0008529	50.0
TH2_k127_5000629_16	Aldo/keto reductase family	K19265	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987	476.0
TH2_k127_5000629_17	4-phosphoerythronate dehydrogenase activity	K00058	-	1.1.1.399,1.1.1.95	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241	466.0
TH2_k127_5000629_18	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	K00859	-	2.7.1.24	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495	455.0
TH2_k127_5000629_19	Peptidase family M50	K06212,K06402	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171	453.0
TH2_k127_5000629_2	Immune inhibitor A peptidase M6	K09607	-	-	0.0	1037.0
TH2_k127_5000629_20	protein conserved in bacteria	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749	466.0
TH2_k127_5000629_21	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386	451.0
TH2_k127_5000629_22	Glycosyl transferase family 2	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461	434.0
TH2_k127_5000629_23	PFAM oxidoreductase domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899	421.0
TH2_k127_5000629_24	Peptidase_C39 like family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507	426.0
TH2_k127_5000629_25	Belongs to the binding-protein-dependent transport system permease family	K02057	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218	419.0
TH2_k127_5000629_26	Parallel beta-helix repeats	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644	457.0
TH2_k127_5000629_27	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	K02007	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721	411.0
TH2_k127_5000629_28	Glucose / Sorbosone dehydrogenase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949	408.0
TH2_k127_5000629_29	Polysaccharide biosynthesis protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458	400.0
TH2_k127_5000629_3	Sulfate permease family	K03321	-	-	8.938e-264	823.0
TH2_k127_5000629_30	PFAM PUCC protein	K08226	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195	406.0
TH2_k127_5000629_31	Tetratricopeptide repeat	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767	403.0
TH2_k127_5000629_32	Glycosyl transferase, family 2	K00786	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715	389.0
TH2_k127_5000629_33	Belongs to the binding-protein-dependent transport system permease family	K02057	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525	386.0
TH2_k127_5000629_34	Metallo-beta-lactamase superfamily	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187	373.0
TH2_k127_5000629_35	Protein of unknown function DUF115	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251	370.0
TH2_k127_5000629_36	4Fe-4S double cluster binding domain	K18979	-	1.17.99.6	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491	370.0
TH2_k127_5000629_37	Glycosyltransferase like family 2	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206	363.0
TH2_k127_5000629_38	PFAM short-chain dehydrogenase reductase SDR	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297	360.0
TH2_k127_5000629_39	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379	364.0
TH2_k127_5000629_4	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	K02335	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	3.813e-261	834.0
TH2_k127_5000629_40	Belongs to the RNA methyltransferase TrmD family	K00554	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747	355.0
TH2_k127_5000629_41	PFAM YbbR family protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977	361.0
TH2_k127_5000629_42	PFAM Shikimate quinate 5-dehydrogenase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008856	354.0
TH2_k127_5000629_43	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	K03787	-	3.1.3.5	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715	346.0
TH2_k127_5000629_44	heme binding	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052	350.0
TH2_k127_5000629_45	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	K18672	-	2.7.7.85	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191	341.0
TH2_k127_5000629_46	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037	333.0
TH2_k127_5000629_47	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	K00826	-	2.6.1.42	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223	333.0
TH2_k127_5000629_48	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092	339.0
TH2_k127_5000629_49	PFAM major facilitator superfamily MFS_1	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467	334.0
TH2_k127_5000629_5	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	K04077	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	8.633e-258	803.0
TH2_k127_5000629_50	ABC-type transport system, periplasmic component surface lipoprotein	K02058	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294	329.0
TH2_k127_5000629_51	ABC transporter	K02006	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887	321.0
TH2_k127_5000629_52	Tetratricopeptide repeat	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626	330.0
TH2_k127_5000629_53	transmembrane transport	K02025,K15771	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504	313.0
TH2_k127_5000629_54	Ig-like domain from next to BRCA1 gene	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577	304.0
TH2_k127_5000629_55	cytidylyl-transferase	K00983	-	2.7.7.43	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377	295.0
TH2_k127_5000629_56	amino acid transport	K02030	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001146	294.0
TH2_k127_5000629_57	Belongs to the enoyl-CoA hydratase isomerase family	K01692,K01715	-	4.2.1.17	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002823	289.0
TH2_k127_5000629_58	transferase activity, transferring acyl groups	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007969	299.0
TH2_k127_5000629_59	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001844	316.0
TH2_k127_5000629_6	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	K02470	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	3.96e-248	781.0
TH2_k127_5000629_60	FIST N domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000001352	286.0
TH2_k127_5000629_61	oxidoreductase activity	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000003967	280.0
TH2_k127_5000629_62	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000007175	307.0
TH2_k127_5000629_63	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	K02008	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000001129	265.0
TH2_k127_5000629_64	heme binding	K21472	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000009289	260.0
TH2_k127_5000629_65	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000861	283.0
TH2_k127_5000629_66	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	K03218,K05926	-	2.1.1.185,2.1.1.230	0.00000000000000000000000000000000000000000000000000000000000000000000000002109	260.0
TH2_k127_5000629_67	PFAM major facilitator superfamily MFS_1	K08151	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000007112	263.0
TH2_k127_5000629_68	aminoglycoside 3-N-acetyltransferase activity	K00662	-	2.3.1.81	0.0000000000000000000000000000000000000000000000000000000000000000000000008912	254.0
TH2_k127_5000629_69	PFAM SMP-30 Gluconolaconase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000005879	245.0
TH2_k127_5000629_7	PFAM ABC transporter related	K02056	-	3.6.3.17	8.471e-220	694.0
TH2_k127_5000629_70	glycerophosphodiester transmembrane transport	K02026	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000002088	247.0
TH2_k127_5000629_71	TIGRFAM DNA polymerase III, delta' subunit	K02340	-	2.7.7.7	0.000000000000000000000000000000000000000000000000000000000000000000002261	247.0
TH2_k127_5000629_72	Ig-like domain from next to BRCA1 gene	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000282	249.0
TH2_k127_5000629_73	phosphorelay signal transduction system	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000003786	250.0
TH2_k127_5000629_74	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	K03769	-	5.2.1.8	0.0000000000000000000000000000000000000000000000000000000000000005424	229.0
TH2_k127_5000629_75	PFAM histone deacetylase superfamily	-	-	-	0.000000000000000000000000000000000000000000000000000000000000005368	229.0
TH2_k127_5000629_76	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	K02428	-	3.6.1.66	0.00000000000000000000000000000000000000000000000000000000000003825	220.0
TH2_k127_5000629_77	molybdenum cofactor guanylyltransferase activity	K03752,K13818	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	0.000000000000000000000000000000000000000000000000000000000003466	218.0
TH2_k127_5000629_78	Acyltransferase	-	-	-	0.0000000000000000000000000000000000000000000000000000000001369	209.0
TH2_k127_5000629_79	Protein conserved in bacteria	-	-	-	0.0000000000000000000000000000000000000000000000000000000004031	217.0
TH2_k127_5000629_8	PFAM TPR repeat-containing protein	-	-	-	1.741e-208	672.0
TH2_k127_5000629_80	ABC transporter substrate-binding protein PnrA-like	K07335	-	-	0.00000000000000000000000000000000000000000000000000000001093	211.0
TH2_k127_5000629_81	Responsible for synthesis of pseudouridine from uracil	K06177	-	5.4.99.28,5.4.99.29	0.00000000000000000000000000000000000000000000000000000001597	207.0
TH2_k127_5000629_82	arylsulfatase activity	-	-	-	0.000000000000000000000000000000000000000000000000000001129	211.0
TH2_k127_5000629_83	PFAM GCN5-related N-acetyltransferase	-	-	-	0.000000000000000000000000000000000000000000000000000001687	204.0
TH2_k127_5000629_84	DNA methylase	-	-	-	0.0000000000000000000000000000000000000000000000000002177	207.0
TH2_k127_5000629_85	PFAM Formylglycine-generating sulfatase enzyme	K12132	-	2.7.11.1	0.0000000000000000000000000000000000000000000000000002629	198.0
TH2_k127_5000629_86	LysM domain	-	-	-	0.00000000000000000000000000000000000000000000000003141	189.0
TH2_k127_5000629_87	acyl-phosphate glycerol-3-phosphate acyltransferase activity	K08591	-	2.3.1.15	0.0000000000000000000000000000000000000000000000001441	185.0
TH2_k127_5000629_89	ABC-2 family transporter protein	K01992	-	-	0.00000000000000000000000000000000000000000001861	169.0
TH2_k127_5000629_9	GTPase that plays an essential role in the late steps of ribosome biogenesis	K03977	-	-	1.393e-207	653.0
TH2_k127_5000629_91	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	0.00000000000000000000000000000000000000001077	179.0
TH2_k127_5000629_92	-	-	-	-	0.0000000000000000000000000000000000000007244	158.0
TH2_k127_5000629_93	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	K04078	-	-	0.000000000000000000000000000000000000001084	149.0
TH2_k127_5000629_94	-	K14340	-	-	0.00000000000000000000000000000000000000169	167.0
TH2_k127_5000629_95	phosphatidate phosphatase activity	K01096,K19302	-	3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	0.000000000000000000000000000000000000003346	154.0
TH2_k127_5000629_97	Acetyltransferase (GNAT) domain	-	-	-	0.00000000000000000000000000000000000000876	152.0
TH2_k127_5000629_98	Belongs to the Fur family	K03711	-	-	0.0000000000000000000000000000000000008232	143.0
TH2_k127_5000629_99	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	0.000000000000000000000000000000000002799	145.0
TH2_k127_5068435_0	PFAM ABC transporter	K06020	-	3.6.3.25	1.059e-261	816.0
TH2_k127_5068435_1	PFAM ABC transporter transmembrane region	-	-	-	2.371e-221	701.0
TH2_k127_5068435_10	PFAM binding-protein-dependent transport systems inner membrane component	K02034	-	-	0.000000000000000000000000000000000000000000000000000000000000000000007042	236.0
TH2_k127_5068435_11	Beta-lactamase class C and other penicillin binding	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000001052	236.0
TH2_k127_5068435_12	Nudix hydrolase	-	-	-	0.00000000000000000000000000000000000000000000000008488	182.0
TH2_k127_5068435_13	regulation of single-species biofilm formation	K02342,K03763,K13573	-	2.7.7.7	0.000000000000000000000000000000000000007187	157.0
TH2_k127_5068435_14	cellulase activity	-	-	-	0.000000000000000000007492	109.0
TH2_k127_5068435_15	Acetyltransferase (GNAT) family	-	-	-	0.00000000000000003506	92.0
TH2_k127_5068435_16	Psort location Cytoplasmic, score	-	-	-	0.00000000002002	70.0
TH2_k127_5068435_17	Peptidase family S51	K13282	-	3.4.15.6	0.00000006898	63.0
TH2_k127_5068435_18	-	-	-	-	0.0000001897	60.0
TH2_k127_5068435_2	ABC transporter, transmembrane region	K06147	-	-	6.52e-204	650.0
TH2_k127_5068435_3	PFAM glycoside hydrolase, family 1	K05350	-	3.2.1.21	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702	590.0
TH2_k127_5068435_4	peptidase activity, acting on L-amino acid peptides	K01337,K01400,K20276	-	3.4.21.50,3.4.24.28	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105	596.0
TH2_k127_5068435_5	Peptidase family M20/M25/M40	K02083,K06016	-	3.5.1.6,3.5.1.87,3.5.3.9	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004516	289.0
TH2_k127_5068435_6	Fibronectin type 3 domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000645	299.0
TH2_k127_5068435_7	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	K03218	-	2.1.1.185	0.00000000000000000000000000000000000000000000000000000000000000000000008548	247.0
TH2_k127_5068435_8	adenosine deaminase	K01488	-	3.5.4.4	0.0000000000000000000000000000000000000000000000000000000000000000000003165	250.0
TH2_k127_5068435_9	aminoglycoside hydroxyurea antibiotic resistance kinase	K04343	-	2.7.1.72	0.000000000000000000000000000000000000000000000000000000000000000000001654	248.0
TH2_k127_5087294_0	Isocitrate/isopropylmalate dehydrogenase	K00031	-	1.1.1.42	1.142e-221	696.0
TH2_k127_5087294_1	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	K11540	GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002119,GO:0002134,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0022612,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035295,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0055086,GO:0055123,GO:0060465,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1905905	2.1.3.2,3.5.2.3,6.3.5.5	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257	404.0
TH2_k127_5087294_2	Planctomycete cytochrome C	-	-	-	0.00001059	53.0
TH2_k127_5178122_0	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	K02931	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331	292.0
TH2_k127_5178122_1	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	K02988	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000002641	262.0
TH2_k127_5178122_2	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	K02933	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.0000000000000000000000000000000000000000000000000000000000000000000004795	244.0
TH2_k127_5178122_3	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	K02881	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	0.00000000000000000000000000000000000000002833	154.0
TH2_k127_5178122_4	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	K02895	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.0000000000000000000000000000000000000001785	152.0
TH2_k127_5178122_5	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	K02994	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.000000000000000000000000000000000002796	138.0
TH2_k127_5178122_6	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	K02954	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.000000000000000000000000001044	113.0
TH2_k127_5178122_7	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	K02994	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.000000000000000002733	85.0
TH2_k127_5184290_0	SMART Elongator protein 3 MiaB NifB	-	-	-	0.000000000000000000000000000000000000000000000000543	177.0
TH2_k127_5184290_1	MFS/sugar transport protein	K03292	-	-	0.00000000000000000000000000000000000000005282	167.0
TH2_k127_5307267_0	MacB-like periplasmic core domain	K02004	-	-	0.0000000000000000000000000000000000000007998	155.0
TH2_k127_5307267_1	PFAM secretion protein HlyD family protein	-	-	-	0.0000000000000000000000000000001963	138.0
TH2_k127_5325045_0	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	-	6.92e-243	758.0
TH2_k127_5325045_1	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	K00820,K15916	-	2.6.1.16,5.3.1.8,5.3.1.9	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361	403.0
TH2_k127_5325045_2	Ig-like domain from next to BRCA1 gene	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000003976	275.0
TH2_k127_5325045_3	Haloacid dehalogenase domain protein hydrolase	-	-	-	0.000000000000000000000000000000000000000000000000007128	186.0
TH2_k127_5325045_4	exo-alpha-(2->6)-sialidase activity	K01186	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	0.000000000000000000000000000000000000000000000001662	201.0
TH2_k127_5325045_5	Domain of unknown function (DUF389)	-	-	-	0.00000000000000000000000000000000000000000000008097	185.0
TH2_k127_5325045_6	Uncharacterised protein family UPF0047	-	-	-	0.000000000000000000000000000000000000000004093	160.0
TH2_k127_5325045_7	Ig-like domain from next to BRCA1 gene	K17987	-	-	0.00000000000000008567	96.0
TH2_k127_5325045_8	PspC domain	K03973	-	-	0.00000000000002372	74.0
TH2_k127_5325045_9	-	-	-	-	0.000000004153	61.0
TH2_k127_5457732_0	histidine kinase A domain protein	-	-	-	0.0	1819.0
TH2_k127_5457732_1	Hexapeptide repeat of succinyl-transferase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536	610.0
TH2_k127_5457732_10	Serine aminopeptidase, S33	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000001838	278.0
TH2_k127_5457732_11	Domain of unknown function (DUF4388)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000001298	271.0
TH2_k127_5457732_12	Domain of unknown function (DUF4126)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000008171	220.0
TH2_k127_5457732_13	4-vinyl reductase, 4VR	-	-	-	0.00000000000000000000000000000000000000000000000000000000003392	213.0
TH2_k127_5457732_14	Predicted membrane protein (DUF2085)	-	-	-	0.000000000000000000000000000000000000000000000000000003468	208.0
TH2_k127_5457732_15	cheY-homologous receiver domain	-	-	-	0.000000000000000000000000000000000000000000000000004092	183.0
TH2_k127_5457732_16	PFAM Thiamin pyrophosphokinase, catalytic region	K00949	-	2.7.6.2	0.0000000000000000000000000000000000000000000001336	178.0
TH2_k127_5457732_17	Protein of unknown function (DUF402)	K07586	-	-	0.000000000000000000000000000000005507	134.0
TH2_k127_5457732_18	energy transducer activity	K03531,K03832	-	-	0.0009538	45.0
TH2_k127_5457732_2	Binding-protein-dependent transport system inner membrane component	K02063	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526	495.0
TH2_k127_5457732_3	Bacterial extracellular solute-binding protein	K02064	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822	463.0
TH2_k127_5457732_4	Response regulator receiver	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557	454.0
TH2_k127_5457732_5	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	K21071	-	2.7.1.11,2.7.1.90	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983	422.0
TH2_k127_5457732_6	PFAM alpha beta hydrolase fold	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014	401.0
TH2_k127_5457732_7	PFAM Shikimate quinate 5-dehydrogenase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038	376.0
TH2_k127_5457732_8	TOBE domain	K02062,K11072	-	3.6.3.31	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451	342.0
TH2_k127_5457732_9	TIGRFAM small GTP-binding protein	K06945	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239	310.0
TH2_k127_5486194_0	Alpha beta	-	-	-	0.00000000000000000000000000000000004746	141.0
TH2_k127_5486194_1	domain, Protein	-	-	-	0.0000000001838	75.0
TH2_k127_5486194_2	PFAM glycoside hydrolase family 39	-	-	-	0.00000004585	67.0
TH2_k127_5488569_0	phenylalanyl-tRNA synthetase beta subunit	K01890	-	6.1.1.20	5.9e-322	1005.0
TH2_k127_5488569_1	Aromatic amino acid lyase	K01745	-	4.3.1.3	2.288e-250	781.0
TH2_k127_5488569_10	PFAM Translin	K07477	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000005484	249.0
TH2_k127_5488569_11	PFAM LmbE family protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000003719	237.0
TH2_k127_5488569_12	glycolate biosynthetic process	K01091	-	3.1.3.18	0.000000000000000000000000000000000000000000000000000000000001078	216.0
TH2_k127_5488569_13	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	K01889	-	6.1.1.20	0.0000000000000000000000000000000000000000000000000000000008109	202.0
TH2_k127_5488569_14	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	K03111	-	-	0.0000000000000000000000000000000000000000000000000002234	189.0
TH2_k127_5488569_15	Dihydroxyacetone kinase family	-	-	-	0.00000000000000000000000000000000000000000000000001248	192.0
TH2_k127_5488569_16	Belongs to the D-alanine--D-alanine ligase family	K01921	-	6.3.2.4	0.00000000000000000000000000000007954	130.0
TH2_k127_5488569_17	nucleoside 2-deoxyribosyltransferase	-	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	-	0.0000000000000000000000000000001809	128.0
TH2_k127_5488569_18	Acetyltransferase (GNAT) family	-	-	-	0.0000000000000000405	93.0
TH2_k127_5488569_19	Histidine kinase	K01768,K12132	-	2.7.11.1,4.6.1.1	0.00000000000000004692	85.0
TH2_k127_5488569_2	Lysine-2,3-aminomutase	K01843	-	5.4.3.2	1.107e-239	747.0
TH2_k127_5488569_20	Prokaryotic cytochrome b561	K12262	-	-	0.000000000000001015	81.0
TH2_k127_5488569_21	Putative esterase	-	-	-	0.000000000000001038	78.0
TH2_k127_5488569_23	WD domain, G-beta repeat	-	-	-	0.00000001299	65.0
TH2_k127_5488569_26	ZZ type zinc finger domain protein	K17987,K21997	GO:0000322,GO:0000323,GO:0000324,GO:0000328,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005771,GO:0005773,GO:0005775,GO:0006914,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016236,GO:0031410,GO:0031974,GO:0031982,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044248,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0051179,GO:0051641,GO:0061919,GO:0061957,GO:0070013,GO:0070727,GO:0072665,GO:0097708,GO:0120113	-	0.0001057	53.0
TH2_k127_5488569_27	ubiquitin binding	-	-	-	0.0002886	51.0
TH2_k127_5488569_3	PhoQ Sensor	K07682	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546	406.0
TH2_k127_5488569_4	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695	388.0
TH2_k127_5488569_5	PhoQ Sensor	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572	334.0
TH2_k127_5488569_6	His Kinase A (phosphoacceptor) domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562	327.0
TH2_k127_5488569_7	myo-inosose-2 dehydratase activity	K10709	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452	308.0
TH2_k127_5488569_8	L-asparaginase II	K01424	-	3.5.1.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818	307.0
TH2_k127_5488569_9	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836	301.0
TH2_k127_5493215_0	PFAM glycosyl transferase family 3	K00756	-	2.4.2.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989	585.0
TH2_k127_5493215_1	Tetratricopeptide TPR_2 repeat protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367	342.0
TH2_k127_5510473_0	helix_turn_helix, Lux Regulon	K03556	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556	610.0
TH2_k127_5531410_0	ABC transporter transmembrane region	K06147	-	-	9.566e-248	780.0
TH2_k127_5531410_1	Peptidase family S58	K01266	-	3.4.11.19	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248	486.0
TH2_k127_5531410_10	acetyltransferase	-	-	-	0.0000000000000000000000000000000000000000000006416	180.0
TH2_k127_5531410_11	PFAM Resolvase, N terminal domain	-	-	-	0.000000000000000000000000000000000000000000001598	168.0
TH2_k127_5531410_12	Involved in initiation control of chromosome replication	-	-	-	0.000000000000000000000000000000000008132	138.0
TH2_k127_5531410_13	haloacid dehalogenase-like hydrolase	K01079	-	3.1.3.3	0.000000000000000000000000000000000009087	149.0
TH2_k127_5531410_14	F420H(2)-dependent quinone reductase	-	-	-	0.00000000000000000000002538	106.0
TH2_k127_5531410_15	PFAM Resolvase, N terminal domain	-	-	-	0.000000000007473	67.0
TH2_k127_5531410_17	Transposase, IS605 OrfB family	K07496	-	-	0.000000003769	61.0
TH2_k127_5531410_18	Putative peptidoglycan binding domain	K17733	-	-	0.0000002522	63.0
TH2_k127_5531410_2	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	K07056	-	2.1.1.198	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002611	287.0
TH2_k127_5531410_20	Concanavalin A-like lectin/glucanases superfamily	-	-	-	0.000002873	60.0
TH2_k127_5531410_21	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	0.000003517	51.0
TH2_k127_5531410_3	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000002825	269.0
TH2_k127_5531410_4	B3 4 domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000007128	265.0
TH2_k127_5531410_5	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000005502	251.0
TH2_k127_5531410_6	NADH:flavin oxidoreductase / NADH oxidase family	K10680	-	-	0.000000000000000000000000000000000000000000000000000000000000000005384	240.0
TH2_k127_5531410_7	PFAM MOSC domain containing protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000009592	225.0
TH2_k127_5531410_8	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	0.0000000000000000000000000000000000000000000000000001213	207.0
TH2_k127_5531410_9	-	-	-	-	0.0000000000000000000000000000000000000000000000001346	189.0
TH2_k127_5578002_0	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	K02886	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299	471.0
TH2_k127_5578002_1	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	K02906	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036	336.0
TH2_k127_5578002_10	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	K02890	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.000000000000000000000000000000000001712	140.0
TH2_k127_5578002_11	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	K02961	-	-	0.0000000000000000000000000000005968	123.0
TH2_k127_5578002_12	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	K02892	-	-	0.00000000000000000000000000003506	120.0
TH2_k127_5578002_13	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	K02954	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.000000000000000000000000005092	111.0
TH2_k127_5578002_14	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	K02994	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.0000000000000000000000006509	108.0
TH2_k127_5578002_15	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	K02358	-	-	0.00000000000000000266	84.0
TH2_k127_5578002_16	Belongs to the universal ribosomal protein uL29 family	K02904	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.0000000003441	64.0
TH2_k127_5578002_2	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	K02982	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284	326.0
TH2_k127_5578002_3	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	K02931	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001596	288.0
TH2_k127_5578002_4	Forms part of the polypeptide exit tunnel	K02926	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000005868	271.0
TH2_k127_5578002_5	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	K02878	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	0.0000000000000000000000000000000000000000000000000000000000000000005219	230.0
TH2_k127_5578002_6	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	K02874	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	0.000000000000000000000000000000000000000000000000000000000000003446	218.0
TH2_k127_5578002_7	Involved in the binding of tRNA to the ribosomes	K02946	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.000000000000000000000000000000000000000000000000000004274	190.0
TH2_k127_5578002_8	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	K02965	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	0.000000000000000000000000000000000000000000007141	163.0
TH2_k127_5578002_9	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	K02895	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.00000000000000000000000000000000000000119	149.0
TH2_k127_5617734_0	glycosyl hydrolase 38 domain protein	K01191	-	3.2.1.24	0.0	1244.0
TH2_k127_5617734_1	Multicopper oxidase	-	-	-	0.0	1088.0
TH2_k127_5617734_10	CoA binding domain	K09181	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284	553.0
TH2_k127_5617734_11	PFAM D-galactarate dehydratase Altronate hydrolase	K16846	-	4.4.1.24	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423	523.0
TH2_k127_5617734_12	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672	519.0
TH2_k127_5617734_13	Belongs to the glycosyl hydrolase 1 family	K05350	-	3.2.1.21	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774	489.0
TH2_k127_5617734_14	Oxidoreductase family, NAD-binding Rossmann fold	K00118,K13020	-	1.1.1.335,1.1.99.28	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157	471.0
TH2_k127_5617734_15	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452	464.0
TH2_k127_5617734_16	polysaccharide catabolic process	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705	472.0
TH2_k127_5617734_17	-	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763	463.0
TH2_k127_5617734_18	MFS/sugar transport protein	K03292	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246	437.0
TH2_k127_5617734_19	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627	422.0
TH2_k127_5617734_2	Family 4 glycosyl hydrolase	K07406	-	3.2.1.22	4.485e-261	807.0
TH2_k127_5617734_20	Bacterial extracellular solute-binding protein	K02027	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352	427.0
TH2_k127_5617734_21	carbohydrate transport	K02027	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723	426.0
TH2_k127_5617734_22	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243	423.0
TH2_k127_5617734_23	Aminotransferase class I and II	K00812	-	2.6.1.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194	422.0
TH2_k127_5617734_24	PFAM binding-protein-dependent transport systems inner membrane component	K02025,K15771	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138	399.0
TH2_k127_5617734_25	MFS/sugar transport protein	K03292	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097	395.0
TH2_k127_5617734_26	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of	K02775,K16371	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875	390.0
TH2_k127_5617734_27	pfkB family carbohydrate kinase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983	383.0
TH2_k127_5617734_28	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	K02015	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918	385.0
TH2_k127_5617734_29	Domain of unknown function (DUF2088)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312	387.0
TH2_k127_5617734_3	Aldehyde ferredoxin oxidoreductase, N-terminal domain	K03738	-	1.2.7.5	6.974e-221	702.0
TH2_k127_5617734_30	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158	379.0
TH2_k127_5617734_31	glycerophosphodiester transmembrane transport	K02026	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258	372.0
TH2_k127_5617734_32	Metallopeptidase family M24	K18829	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071	374.0
TH2_k127_5617734_33	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	K01635	-	4.1.2.40	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191	370.0
TH2_k127_5617734_34	transmembrane transport	K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184	368.0
TH2_k127_5617734_35	PFAM binding-protein-dependent transport systems inner membrane component	K02025	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106	365.0
TH2_k127_5617734_36	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805	360.0
TH2_k127_5617734_37	Lipocalin-like domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201	353.0
TH2_k127_5617734_38	ROK family	K00847	-	2.7.1.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182	347.0
TH2_k127_5617734_39	Flavin containing amine oxidoreductase	K06955	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615	341.0
TH2_k127_5617734_4	MacB-like periplasmic core domain	K02004	-	-	1.316e-204	667.0
TH2_k127_5617734_40	DeoR C terminal sensor domain	K02081	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098	330.0
TH2_k127_5617734_41	ErfK ybiS ycfS ynhG family protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212	336.0
TH2_k127_5617734_42	PFAM major facilitator superfamily MFS_1	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007821	338.0
TH2_k127_5617734_43	PFAM cytochrome c biogenesis protein, transmembrane region	K06196	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399	325.0
TH2_k127_5617734_44	helix_turn _helix lactose operon repressor	K02529	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017	329.0
TH2_k127_5617734_45	glycerophosphodiester transmembrane transport	K02026	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592	323.0
TH2_k127_5617734_46	Domain of unknown function (DUF4874)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058	331.0
TH2_k127_5617734_47	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	K04077	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317	311.0
TH2_k127_5617734_48	Predicted membrane protein (DUF2085)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002137	295.0
TH2_k127_5617734_49	SIS domain	K00820	-	2.6.1.16	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002715	289.0
TH2_k127_5617734_5	Belongs to the glycosyl hydrolase 31 family	K01811	GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0016787,GO:0016798,GO:0042802,GO:0080176	3.2.1.177	1.086e-197	640.0
TH2_k127_5617734_50	PFAM dienelactone hydrolase	K01061	-	3.1.1.45	0.000000000000000000000000000000000000000000000000000000000000000000000000000000001382	281.0
TH2_k127_5617734_51	Belongs to the multicopper oxidase YfiH RL5 family	K05810	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000001733	275.0
TH2_k127_5617734_52	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000002847	278.0
TH2_k127_5617734_53	periplasmic binding protein	K02016	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000002847	278.0
TH2_k127_5617734_54	Family 4 glycosyl hydrolase	K01222,K07406	-	3.2.1.22,3.2.1.86	0.00000000000000000000000000000000000000000000000000000000000000000000000000000003904	283.0
TH2_k127_5617734_55	PFAM binding-protein-dependent transport systems inner membrane component	K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17316	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000005081	276.0
TH2_k127_5617734_56	Binding-protein-dependent transport system inner membrane component	K02026	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000004898	278.0
TH2_k127_5617734_57	Conserved hypothetical protein 698	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000001702	273.0
TH2_k127_5617734_58	PFAM ABC transporter related	K02003	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000279	265.0
TH2_k127_5617734_59	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	K06997	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000001289	258.0
TH2_k127_5617734_6	amidohydrolase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562	580.0
TH2_k127_5617734_60	glycerophosphodiester transmembrane transport	K02026,K05815	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000001433	257.0
TH2_k127_5617734_61	Transaldolase/Fructose-6-phosphate aldolase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000001	245.0
TH2_k127_5617734_62	PFAM ABC transporter related	K02013	-	3.6.3.34	0.00000000000000000000000000000000000000000000000000000000000000000001372	241.0
TH2_k127_5617734_63	COG1874 Beta-galactosidase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000004939	235.0
TH2_k127_5617734_64	PFAM Patatin	K07001	-	-	0.000000000000000000000000000000000000000000000000000000000000002716	227.0
TH2_k127_5617734_65	PFAM ROK family protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000008431	229.0
TH2_k127_5617734_66	Galactokinase galactose-binding signature	K18677,K19347	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019586,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046396,GO:0046835,GO:0047912,GO:0071704	2.7.1.44	0.000000000000000000000000000000000000000000000000000000000006348	229.0
TH2_k127_5617734_67	PFAM extracellular solute-binding protein, family 5	K02035,K15580	-	-	0.00000000000000000000000000000000000000000000000000000000002282	238.0
TH2_k127_5617734_68	ABC transporter substrate-binding protein	-	-	-	0.000000000000000000000000000000000000000000000001337	190.0
TH2_k127_5617734_69	GlcNAc-PI de-N-acetylase	-	-	-	0.0000000000000000000000000000000000000000001249	168.0
TH2_k127_5617734_7	oxidoreductase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525	574.0
TH2_k127_5617734_70	SOUL heme-binding protein	-	-	-	0.00000000000000000000000000000000000000001248	160.0
TH2_k127_5617734_71	Aminoacyl-tRNA editing domain	K19055	-	-	0.0000000000000000000000000000000000001737	147.0
TH2_k127_5617734_72	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	0.0000000000000000000000000000000000008055	155.0
TH2_k127_5617734_73	ABC-type sugar transport system periplasmic component	-	-	-	0.000000000000000000000000000000000003673	154.0
TH2_k127_5617734_74	Belongs to the UPF0235 family	K09131	-	-	0.00000000000000000000000000000000006556	135.0
TH2_k127_5617734_75	Iron-containing alcohol dehydrogenase	K00096	-	1.1.1.261	0.0000000000000000000000000000000002475	139.0
TH2_k127_5617734_76	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	0.0000000000000000000000000000000009138	148.0
TH2_k127_5617734_77	PFAM phospholipase Carboxylesterase	K06999	-	-	0.00000000000000000000000000000002521	135.0
TH2_k127_5617734_78	Transposase DDE domain	-	-	-	0.0000000000000000000000000001502	120.0
TH2_k127_5617734_79	N-acetylglucosaminylinositol deacetylase activity	-	-	-	0.000000000000000000000000005171	125.0
TH2_k127_5617734_8	Lytic transglycosylase catalytic	K08309	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173	596.0
TH2_k127_5617734_80	Dodecin	K09165	-	-	0.00000000000000000000000005832	108.0
TH2_k127_5617734_81	cellulose binding	-	-	-	0.0000000000000000000000001187	118.0
TH2_k127_5617734_82	transferase hexapeptide repeat containing protein	K00973	-	2.7.7.24	0.0000000000000000000000001443	123.0
TH2_k127_5617734_83	SAF	K16845	-	4.4.1.24	0.000000000000000000000001047	107.0
TH2_k127_5617734_84	alginic acid biosynthetic process	K01406	-	3.4.24.40	0.000000000000000000000003832	121.0
TH2_k127_5617734_85	Protein conserved in bacteria	-	-	-	0.000000000000000001626	85.0
TH2_k127_5617734_86	Predicted membrane protein (DUF2177)	-	-	-	0.000000000000001337	81.0
TH2_k127_5617734_87	-	-	-	-	0.000000000000002233	80.0
TH2_k127_5617734_88	cobalamin binding	-	-	-	0.000000000000003831	83.0
TH2_k127_5617734_89	integral membrane protein	K02221	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.000000000000009754	76.0
TH2_k127_5617734_9	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973	547.0
TH2_k127_5617734_90	COG3666 Transposase and inactivated derivatives	-	-	-	0.0000000000006915	71.0
TH2_k127_5617734_93	Hypothetical glycosyl hydrolase 6	-	-	-	0.00002468	57.0
TH2_k127_5617734_94	Mut7-C ubiquitin	K03154	-	-	0.00009998	48.0
TH2_k127_5617734_95	His Kinase A (phosphoacceptor) domain	-	-	-	0.0006046	44.0
TH2_k127_5617734_96	DDE superfamily endonuclease	-	-	-	0.0006633	48.0
TH2_k127_5617734_97	-	-	-	-	0.0009007	49.0
TH2_k127_5630173_0	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	K09458	-	2.3.1.179	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931	501.0
TH2_k127_5630173_1	DinB superfamily	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035	309.0
TH2_k127_5630173_2	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	K02356	-	-	0.0000000000000000000000000000000000000000000001063	171.0
TH2_k127_5633229_0	PhoQ Sensor	-	-	-	0.00000000000000000000000001309	125.0
TH2_k127_5636287_0	PFAM extracellular solute-binding protein, family 5	K02035	-	-	0.0000000000000000000000000000000000000000000000000000000000000000006656	241.0
TH2_k127_5636287_1	Cytochrome C oxidase, cbb3-type, subunit III	K08738	-	-	0.0000000009924	64.0
TH2_k127_5650874_0	PEP-utilising enzyme, mobile domain	K01007	-	2.7.9.2	0.00000000000000000000000000000000000000000000000000008342	204.0
TH2_k127_5650874_1	Glyoxalase-like domain	-	-	-	0.0000003161	54.0
TH2_k127_5655232_0	Pyridoxal-phosphate dependent enzyme	K01733	-	4.2.3.1	0.000000000000000000000000000000000000000000000003158	179.0
TH2_k127_5655232_1	PFAM response regulator receiver	K11443	-	-	0.000000000000000000000000000000000000003404	149.0
TH2_k127_5655232_2	PFAM response regulator receiver	K11443	-	-	0.00000000000000000000000000000007329	129.0
TH2_k127_5655232_3	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	K01733,K22010	-	4.2.3.1	0.0000000000000000000000000000006673	124.0
TH2_k127_5659631_0	ATPase, P-type (transporting), HAD superfamily, subfamily IC	K01537	-	3.6.3.8	2.71e-303	956.0
TH2_k127_5659631_1	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	5.622e-203	652.0
TH2_k127_5659631_10	TIGRFAM small GTP-binding protein	K06945	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183	304.0
TH2_k127_5659631_11	Carbonic anhydrase	K01673	-	4.2.1.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004127	282.0
TH2_k127_5659631_12	PFAM Cytochrome C assembly protein	K02195	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004832	281.0
TH2_k127_5659631_13	Cytochrome c	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000004289	281.0
TH2_k127_5659631_14	Peptidase MA superfamily	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000006894	251.0
TH2_k127_5659631_15	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	K02635	GO:0005575,GO:0005622,GO:0005623,GO:0009512,GO:0009579,GO:0016020,GO:0032991,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464,GO:0070069	-	0.00000000000000000000000000000000000000000000000000000000000001623	226.0
TH2_k127_5659631_16	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	K02197	-	-	0.000000000000000000000000000000000000000000000000000000006075	203.0
TH2_k127_5659631_17	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	K02199	-	-	0.000000000000000000000000000000000000002059	154.0
TH2_k127_5659631_18	-	-	-	-	0.0000000000000000000000000000000000003663	159.0
TH2_k127_5659631_19	Pyridoxamine 5'-phosphate oxidase	-	-	-	0.00000000000000000000000000000000005842	143.0
TH2_k127_5659631_2	PFAM Cytochrome C assembly protein	K02198	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608	529.0
TH2_k127_5659631_20	subunit of a heme lyase	K02200	-	-	0.000000000000000000000000000000000125	140.0
TH2_k127_5659631_21	PFAM SNARE associated Golgi protein	-	-	-	0.0000000000000000000000000001801	125.0
TH2_k127_5659631_22	zinc-ribbon domain	-	-	-	0.000000000000000000000000003834	120.0
TH2_k127_5659631_23	Rieske [2Fe-2S] domain	K03886	-	-	0.0000000000000000000007959	101.0
TH2_k127_5659631_24	-	-	-	-	0.00000000000000001466	88.0
TH2_k127_5659631_25	Cytochrome b subunit of the bc complex	K02637	-	-	0.0000000000000002712	84.0
TH2_k127_5659631_27	Amino acid ABC transporter substrate-binding protein	-	-	-	0.0007574	51.0
TH2_k127_5659631_3	Fe-S oxidoreductase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124	505.0
TH2_k127_5659631_5	aldo keto reductase	K19265	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614	424.0
TH2_k127_5659631_6	Bacterial extracellular solute-binding proteins, family 5 Middle	K15580	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322	395.0
TH2_k127_5659631_7	Domain of unknown function (DUF4388)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734	388.0
TH2_k127_5659631_8	PFAM ABC transporter related	K02193	-	3.6.3.41	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573	334.0
TH2_k127_5659631_9	PFAM cytochrome c-type biogenesis protein CcmB	K02194	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616	308.0
TH2_k127_5669751_0	5'-nucleotidase, C-terminal domain	K01119	-	3.1.3.6,3.1.4.16	0.0	1665.0
TH2_k127_5669751_1	elongation factor Tu domain 2 protein	K06207	-	-	1.022e-280	878.0
TH2_k127_5669751_10	SMART phosphoesterase PHP domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486	401.0
TH2_k127_5669751_11	Beta-lactamase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912	402.0
TH2_k127_5669751_12	Beta-lactamase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111	377.0
TH2_k127_5669751_13	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	K01775	-	5.1.1.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155	369.0
TH2_k127_5669751_14	Protein of unknown function (DUF1385)	K09153	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785	358.0
TH2_k127_5669751_15	DNA/RNA non-specific endonuclease	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721	342.0
TH2_k127_5669751_16	Dienelactone hydrolase family	K01061	-	3.1.1.45	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947	344.0
TH2_k127_5669751_17	Peptidase family S51	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141	338.0
TH2_k127_5669751_18	LysM domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522	331.0
TH2_k127_5669751_19	Belongs to the Pirin family	K06911	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394	317.0
TH2_k127_5669751_2	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	K03723	-	-	1.6e-272	877.0
TH2_k127_5669751_20	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	K01259	-	3.4.11.5	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373	306.0
TH2_k127_5669751_21	Methyltransferase domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559	309.0
TH2_k127_5669751_22	Fumarylacetoacetate (FAA) hydrolase family	K16171	-	3.7.1.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081	304.0
TH2_k127_5669751_23	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	K01056	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	0.0000000000000000000000000000000000000000000000000000000000000000000000008594	250.0
TH2_k127_5669751_24	Protein tyrosine kinase	K12132	-	2.7.11.1	0.0000000000000000000000000000000000000000000000000000000000000000000001719	264.0
TH2_k127_5669751_25	Tellurite resistance protein TehB	-	-	-	0.00000000000000000000000000000000000000000000000000000000000001291	222.0
TH2_k127_5669751_26	aromatic amino acid beta-eliminating lyase threonine aldolase	K01620	-	4.1.2.48	0.0000000000000000000000000000000000000000000000000000000000004174	214.0
TH2_k127_5669751_27	Phosphodiester glycosidase	-	-	-	0.00000000000000000000000000000000000000000000000000000000002435	217.0
TH2_k127_5669751_28	Aminoacyl-tRNA editing domain	-	-	-	0.00000000000000000000000000000000000000000000000000000003568	200.0
TH2_k127_5669751_29	Major Facilitator Superfamily	-	-	-	0.00000000000000000000000000000000000000000000000000000003946	212.0
TH2_k127_5669751_3	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	K01937	-	6.3.4.2	1.601e-264	826.0
TH2_k127_5669751_30	PD-(D/E)XK nuclease superfamily	-	-	-	0.00000000000000000000000000000000000000000000000000000009327	205.0
TH2_k127_5669751_31	-	-	-	-	0.00000000000000000000000000000000000000000000000000000173	199.0
TH2_k127_5669751_32	PFAM Roadblock LC7 family protein	K07131	-	-	0.0000000000000000000000000000000000000000000000002105	179.0
TH2_k127_5669751_33	O-methyltransferase	K03183	-	2.1.1.163,2.1.1.201	0.000000000000000000000000000000000000000000000000313	183.0
TH2_k127_5669751_34	NUDIX domain	-	-	-	0.0000000000000000000000000000000000000000000002444	173.0
TH2_k127_5669751_35	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	K03101	-	3.4.23.36	0.000000000000000000000000000000000000000000003397	169.0
TH2_k127_5669751_36	Deoxynucleoside kinase	-	-	-	0.0000000000000000000000000000000000003095	149.0
TH2_k127_5669751_37	Putative phosphatase (DUF442)	-	-	-	0.00000000000000000000000000000000994	133.0
TH2_k127_5669751_38	-	-	-	-	0.0000000000000000000000000000002654	137.0
TH2_k127_5669751_39	DNA-binding transcription factor activity	K03892	-	-	0.00000000000000000000000363	106.0
TH2_k127_5669751_4	PFAM homogentisate 12-dioxygenase	K00451	-	1.13.11.5	2.385e-201	631.0
TH2_k127_5669751_40	Belongs to the Nudix hydrolase family	-	-	-	0.00000000000000000000005303	103.0
TH2_k127_5669751_41	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	K03075	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	0.00000000000000000001129	93.0
TH2_k127_5669751_42	-	-	-	-	0.00000000000000000002085	98.0
TH2_k127_5669751_43	-	-	-	-	0.0000000000000000000573	92.0
TH2_k127_5669751_44	ErfK ybiS ycfS ynhG family protein	-	-	-	0.0000000000000001313	89.0
TH2_k127_5669751_45	Protein of unknown function (DUF4230)	-	-	-	0.0000000000002027	79.0
TH2_k127_5669751_47	PFAM GGDEF domain containing protein	-	-	-	0.000004771	55.0
TH2_k127_5669751_48	cellulase activity	K01218,K12132	-	2.7.11.1,3.2.1.78	0.00008138	53.0
TH2_k127_5669751_5	PFAM extracellular solute-binding protein, family 5	K02035	-	-	2.643e-199	636.0
TH2_k127_5669751_6	4-Hydroxyphenylpyruvate dioxygenase	K00457,K16421	GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.27,1.13.11.46	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009396	577.0
TH2_k127_5669751_7	peptidase dimerisation domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149	501.0
TH2_k127_5669751_8	(ABC) transporter	K06158	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293	457.0
TH2_k127_5669751_9	Responsible for synthesis of pseudouridine from uracil	K06180	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829	404.0
TH2_k127_5671327_0	Wd40 repeat-containing protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433	322.0
TH2_k127_5671327_1	Tetratricopeptide repeat	-	-	-	0.0000000000000000000009666	106.0
TH2_k127_5671327_2	sh3 domain protein	K01227,K03642	-	3.2.1.96	0.00006212	48.0
TH2_k127_5695488_0	TIGRFAM acetylornithine and succinylornithine aminotransferase	K00821,K05830,K09251	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575	2.6.1.11,2.6.1.17,2.6.1.82	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527	569.0
TH2_k127_5695488_1	Aldehyde ferredoxin oxidoreductase, N-terminal domain	K03738	-	1.2.7.5	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148	502.0
TH2_k127_5695488_10	PFAM DNA methylase N-4 N-6	K00571,K07316	-	2.1.1.72	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000713	294.0
TH2_k127_5695488_11	-	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009965	288.0
TH2_k127_5695488_12	phosphorelay signal transduction system	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000001377	233.0
TH2_k127_5695488_13	PFAM alpha beta hydrolase fold	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000006735	232.0
TH2_k127_5695488_14	Belongs to the arginase family	K01479,K01480	-	3.5.3.11,3.5.3.8	0.0000000000000000000000000000000000000000000000000000000358	210.0
TH2_k127_5695488_15	Belongs to the 'phage' integrase family	K04763	-	-	0.0000000000000000000000000000000000000000000000000002461	198.0
TH2_k127_5695488_16	Sulfate permease family	K03321	-	-	0.000000000000000000000000000000000000000000000000001311	197.0
TH2_k127_5695488_17	Transport permease protein	K01992	-	-	0.0000000000000000000000000000000000000000000000003968	191.0
TH2_k127_5695488_18	Carbon-nitrogen hydrolase	K03820	-	-	0.0000000000000000000000000000000000000000000001615	175.0
TH2_k127_5695488_19	Transport permease protein	K01992	-	-	0.0000000000000000000000000000000000001483	156.0
TH2_k127_5695488_2	PFAM ABC transporter related	K01990	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817	426.0
TH2_k127_5695488_20	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	0.00000000000000000000000000001127	126.0
TH2_k127_5695488_21	CAAX protease self-immunity	K07052	-	-	0.0000000000000000000000002081	117.0
TH2_k127_5695488_22	PFAM zinc finger, SWIM domain protein	-	-	-	0.000000000000000000000002166	104.0
TH2_k127_5695488_23	Belongs to the 'phage' integrase family	-	-	-	0.000000000000000007247	95.0
TH2_k127_5695488_24	-	-	-	-	0.00000000000007494	74.0
TH2_k127_5695488_25	-	-	-	-	0.000000000074	65.0
TH2_k127_5695488_26	BetI-type transcriptional repressor, C-terminal	-	-	-	0.0000000000866	70.0
TH2_k127_5695488_27	-	-	-	-	0.0000002805	57.0
TH2_k127_5695488_28	ThiS family	K03636	-	-	0.000001045	55.0
TH2_k127_5695488_3	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	K01950	-	6.3.5.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115	422.0
TH2_k127_5695488_30	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	-	-	-	0.000006962	53.0
TH2_k127_5695488_31	Protein of unknown function (DUF3800)	-	-	-	0.00001001	55.0
TH2_k127_5695488_4	NAD synthase	K01916	-	6.3.1.5	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571	410.0
TH2_k127_5695488_5	PFAM AMP-dependent synthetase and ligase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784	410.0
TH2_k127_5695488_6	Transmembrane secretion effector	K08225	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053	358.0
TH2_k127_5695488_7	ErfK ybiS ycfS ynhG family protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506	349.0
TH2_k127_5695488_8	Carbon-nitrogen hydrolase	K03820	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626	333.0
TH2_k127_5695488_9	Beta-lactamase	K01286	-	3.4.16.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007748	300.0
TH2_k127_5778409_0	Belongs to the peptidase S26 family	K03100	-	3.4.21.89	0.00000000000000000000000000000000000000000000000000000005153	201.0
TH2_k127_5778409_1	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	K19200	-	-	0.0000000000000000000000000000000000000000000000002643	190.0
TH2_k127_5778409_2	Polymer-forming cytoskeletal	-	-	-	0.000000000000000000000000000000000000001188	160.0
TH2_k127_5778409_3	Dual specificity phosphatase, catalytic domain	-	-	-	0.00000000000000000000000000000000000004474	148.0
TH2_k127_5778409_5	One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface	K02714	-	-	0.0007844	42.0
TH2_k127_5786161_0	Alpha amylase, catalytic domain	-	-	-	8.4e-323	1015.0
TH2_k127_5786161_1	amine dehydrogenase activity	K15864	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.2.1,1.7.99.1	8.97e-311	974.0
TH2_k127_5786161_10	PhoQ Sensor	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007738	302.0
TH2_k127_5786161_11	Peptidase M28	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000001951	278.0
TH2_k127_5786161_12	Helix-turn-helix type 11 domain protein	K02081	-	-	0.000000000000000000000000000000000000000000000000000000000000000006421	233.0
TH2_k127_5786161_13	pyridoxamine 5'-phosphate	K07005	-	-	0.00000000000000000000000000000000000000000000000000000000000000007927	226.0
TH2_k127_5786161_14	Cyclic nucleotide-monophosphate binding domain	K21564	-	-	0.00000000000000000000000000000000000000000001461	170.0
TH2_k127_5786161_15	Belongs to the ribulose-phosphate 3-epimerase family	K01783	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	0.0000000000000000000000000000000000000000001224	166.0
TH2_k127_5786161_16	phosphoenolpyruvate-dependent sugar phosphotransferase system	K02768,K02769,K02770	-	2.7.1.202	0.000000000000000000000000000000000003242	143.0
TH2_k127_5786161_17	PFAM NLP P60 protein	-	-	-	0.0000000000000000000000000000000002259	144.0
TH2_k127_5786161_18	Alpha/beta hydrolase family	-	-	-	0.00000000000000000000000001135	119.0
TH2_k127_5786161_19	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity	K02774,K02821,K02822,K03475,K20113	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015711,GO:0015749,GO:0015791,GO:0015796,GO:0015849,GO:0015850,GO:0015882,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0034220,GO:0035461,GO:0044424,GO:0044444,GO:0044464,GO:0046942,GO:0051179,GO:0051180,GO:0051181,GO:0051182,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090584,GO:0090585,GO:0098656,GO:1903825,GO:1905039	2.7.1.194,2.7.1.200,2.7.1.204	0.00000000000000000000000004675	110.0
TH2_k127_5786161_2	galactitol transmembrane transporter activity	K02775	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015791,GO:0015796,GO:0015850,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090584	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307	565.0
TH2_k127_5786161_20	PTS HPr component phosphorylation site	K11189	-	-	0.0000000000000000000441	94.0
TH2_k127_5786161_21	Domain of unknown function (DUF4342)	-	-	-	0.00000000000000001577	88.0
TH2_k127_5786161_22	-	-	-	-	0.0000000000000002009	84.0
TH2_k127_5786161_23	Wd-40 repeat	-	-	-	0.0000000001	70.0
TH2_k127_5786161_24	PFAM Integrase catalytic region	-	-	-	0.00000003183	66.0
TH2_k127_5786161_25	PTS system, Lactose/Cellobiose specific IIB subunit	K02774	-	2.7.1.200	0.00002493	50.0
TH2_k127_5786161_26	PFAM Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	0.00007729	48.0
TH2_k127_5786161_3	acetyltransferase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779	508.0
TH2_k127_5786161_4	PTS HPr component phosphorylation site	K02768,K08483,K11183	-	2.7.1.202,2.7.3.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384	509.0
TH2_k127_5786161_5	Leucyl aminopeptidase (Aminopeptidase T)	K19689	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186	415.0
TH2_k127_5786161_6	peptidase M29	K19689	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471	412.0
TH2_k127_5786161_7	BtpA family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862	373.0
TH2_k127_5786161_8	PTS system Galactitol-specific IIC component	K02775	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119	379.0
TH2_k127_5786161_9	Mandelate racemase muconate lactonizing enzyme	K19802	-	5.1.1.20	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743	306.0
TH2_k127_5842842_0	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	K01895	-	6.2.1.1	3.535e-313	968.0
TH2_k127_5842842_1	Belongs to the aldehyde dehydrogenase family	K00294	-	1.2.1.88	9.989e-247	773.0
TH2_k127_5842842_10	-	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556	376.0
TH2_k127_5842842_11	PFAM binding-protein-dependent transport systems inner membrane component	K02033	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865	342.0
TH2_k127_5842842_12	Polynucleotide adenylyltransferase region	K00974	-	2.7.7.72	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009643	334.0
TH2_k127_5842842_13	N-terminal TM domain of oligopeptide transport permease C	K02034	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213	317.0
TH2_k127_5842842_14	Periplasmic copper-binding protein (NosD)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056	316.0
TH2_k127_5842842_15	CO dehydrogenase/acetyl-CoA synthase delta subunit	K00548	-	2.1.1.13	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004863	289.0
TH2_k127_5842842_16	Trimethylamine methyltransferase (MTTB)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001613	293.0
TH2_k127_5842842_17	PFAM Methyltransferase	K00598	-	2.1.1.144	0.00000000000000000000000000000000000000000000000000000000000000000000000000000003447	276.0
TH2_k127_5842842_18	PFAM extracellular solute-binding protein, family 5	K02035	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000002911	281.0
TH2_k127_5842842_19	PFAM inositol monophosphatase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000001955	261.0
TH2_k127_5842842_2	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	K01881	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	3.052e-237	740.0
TH2_k127_5842842_20	Trimethylamine methyltransferase (MTTB)	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000004027	253.0
TH2_k127_5842842_21	Cellulase (glycosyl hydrolase family 5)	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000008161	254.0
TH2_k127_5842842_22	Cobalt transport protein	K16785	-	-	0.000000000000000000000000000000000000000000000000000000000000001971	228.0
TH2_k127_5842842_23	Methionine synthase B12-binding module cap domain protein	K00548,K14084	-	2.1.1.13	0.0000000000000000000000000000000000000000000000000000000000006516	217.0
TH2_k127_5842842_24	COGs COG0601 ABC-type dipeptide oligopeptide nickel transport systems permease components	K02033	-	-	0.0000000000000000000000000000000000000000000000000000000004636	215.0
TH2_k127_5842842_25	Protein of unknown function (DUF1684)	K09164	-	-	0.0000000000000000000000000000000000000000000000000000000008431	211.0
TH2_k127_5842842_26	PFAM binding-protein-dependent transport systems inner membrane component	K02034	-	-	0.000000000000000000000000000000000000000000000000000001094	203.0
TH2_k127_5842842_27	PFAM peptidase M50	-	-	-	0.00000000000000000000000000000000000000000000000000003829	196.0
TH2_k127_5842842_28	cytokinin biosynthetic process	K06966	-	3.2.2.10	0.0000000000000000000000000000000000000000000000000009092	188.0
TH2_k127_5842842_29	Trimethylamine methyltransferase (MTTB)	K14083	-	2.1.1.250	0.0000000000000000000000000000000000000000000000004193	193.0
TH2_k127_5842842_3	PFAM ABC transporter related	K16786,K16787	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448	608.0
TH2_k127_5842842_30	Protein of unknown function (DUF1684)	K09164	-	-	0.00000000000000000000000000000000000000000000007161	179.0
TH2_k127_5842842_31	trimethylamine methyltransferase	K14083	-	2.1.1.250	0.00000000000000000000000000000000000000000000009208	186.0
TH2_k127_5842842_32	carboxylic ester hydrolase activity	-	-	-	0.00000000000000000000000000000000000000000009638	170.0
TH2_k127_5842842_33	-	K07020,K18614	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0034641,GO:0042365,GO:0042737,GO:0042802,GO:0042803,GO:0042816,GO:0042820,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046983,GO:0047411,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.1.29	0.0000000000000000000000000000000000000001678	154.0
TH2_k127_5842842_34	DNA topological change	-	-	-	0.00000000000000000000000000000000000005533	150.0
TH2_k127_5842842_35	ECF-type riboflavin transporter, S component	K16924	-	-	0.00000000000000000000000000000000001718	147.0
TH2_k127_5842842_36	MazG-like family	-	-	-	0.000000000000000000000000000002059	123.0
TH2_k127_5842842_37	Acetyltransferase (GNAT) domain	-	-	-	0.0000000000000000000000000000271	124.0
TH2_k127_5842842_39	-	-	-	-	0.000000000000000005115	89.0
TH2_k127_5842842_4	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	K01251	-	3.3.1.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649	594.0
TH2_k127_5842842_40	cell redox homeostasis	K03671	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009636,GO:0009987,GO:0010190,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0017004,GO:0019725,GO:0022607,GO:0031976,GO:0031977,GO:0031984,GO:0033554,GO:0034357,GO:0034599,GO:0034622,GO:0042221,GO:0042592,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055035,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0070887,GO:0071840,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	0.00005622	48.0
TH2_k127_5842842_41	NB-ARC domain	-	-	-	0.0006313	48.0
TH2_k127_5842842_42	Belongs to the 2H phosphoesterase superfamily. YjcG family	-	-	-	0.0006382	49.0
TH2_k127_5842842_5	FAD binding domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072	479.0
TH2_k127_5842842_6	Coenzyme A transferase	K01039	-	2.8.3.12	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352	455.0
TH2_k127_5842842_7	PFAM PfkB domain protein	K00856	-	2.7.1.20	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479	426.0
TH2_k127_5842842_8	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	K08963	-	5.3.1.23	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334	417.0
TH2_k127_5842842_9	Coenzyme A transferase	K01040	-	2.8.3.12	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851	401.0
TH2_k127_5864328_0	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	K01733	-	4.2.3.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779	462.0
TH2_k127_5903240_0	PFAM Aldehyde ferredoxin oxidoreductase	K03738	-	1.2.7.5	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627	539.0
TH2_k127_5903240_1	ABC transporter	K01996	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004574	278.0
TH2_k127_5903240_2	Branched-chain amino acid ATP-binding cassette transporter	K01995	-	-	0.0000000000000000000000000000000000000000000000000000000000000000401	230.0
TH2_k127_5903240_3	Belongs to the binding-protein-dependent transport system permease family	K01997	-	-	0.00000000000000000000000000000000000000000000000000000000000006975	223.0
TH2_k127_5903240_4	Creatinine amidohydrolase	K01470,K22232	-	3.5.2.10	0.000000000000000000000000000000000000000000000000000000003379	204.0
TH2_k127_5903240_5	Belongs to the binding-protein-dependent transport system permease family	-	-	-	0.000000000000000000000000000000000000000002019	171.0
TH2_k127_5903240_6	TIGRFAM reductive dehalogenase	-	-	-	0.0000000000000000000000000000000000001678	152.0
TH2_k127_5903240_7	Periplasmic binding protein domain	K01999	-	-	0.000000000000000000000000000000005303	144.0
TH2_k127_5903240_8	PFAM ThiamineS	-	-	-	0.00001643	49.0
TH2_k127_5950741_0	Acetyltransferase (GNAT) family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001418	291.0
TH2_k127_5950741_1	transferase activity, transferring acyl groups	-	-	-	0.000000000000000000000000000000000000000000000000001025	197.0
TH2_k127_5953164_0	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	K02313	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	0.000000000000000000000000000000000000000001348	177.0
TH2_k127_5953164_1	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	0.00000000000000000000000003452	119.0
TH2_k127_5953164_2	Transcriptional regulator, AbiEi antitoxin	-	-	-	0.000000000000003327	83.0
TH2_k127_5970782_0	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976	353.0
TH2_k127_610483_0	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	K08483	GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702	2.7.3.9	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687	478.0
TH2_k127_610483_1	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	K00627	-	2.3.1.12	0.0000000000000000000000000000000000000000000000000000000000000000000000000007708	269.0
TH2_k127_610483_2	PTS HPr component phosphorylation site	K02768,K08483,K11183	-	2.7.1.202,2.7.3.9	0.00000000000000000000009256	100.0
TH2_k127_6156811_0	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	K00341	-	1.6.5.3	3.096e-219	702.0
TH2_k127_6156811_1	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	K00342	-	1.6.5.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564	494.0
TH2_k127_6156811_2	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	K00337	-	1.6.5.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007651	417.0
TH2_k127_6156811_3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00338,K05580	-	1.6.5.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000008441	260.0
TH2_k127_6156811_4	Belongs to the complex I subunit 6 family	K00339	-	1.6.5.3	0.0000000000000000000000000000000000000000006324	162.0
TH2_k127_6156811_5	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00340	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	0.00000000000000000000000000000000858	129.0
TH2_k127_6183089_0	PFAM ATP-binding region, ATPase domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000004381	279.0
TH2_k127_6186259_0	Ethanolamine ammonia lyase large subunit (EutB)	K03735	-	4.3.1.7	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079	469.0
TH2_k127_6186259_1	Enoyl-(Acyl carrier protein) reductase	-	-	-	0.000000000000000000000000000000000000000000000000001254	190.0
TH2_k127_6321508_0	ISFtu1 transposase K01152	-	-	-	0.00000000000000000000000000000000000000000000000000000006659	202.0
TH2_k127_6321508_1	Right handed beta helix region	-	-	-	0.00000000001621	74.0
TH2_k127_6321508_2	COG3415 Transposase and inactivated derivatives	-	-	-	0.00000003467	60.0
TH2_k127_6429890_0	PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein	K00341	-	1.6.5.3	5.807e-303	944.0
TH2_k127_6429890_1	Aldehyde ferredoxin	K03738	-	1.2.7.5	1.361e-301	942.0
TH2_k127_6429890_10	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	K00337	-	1.6.5.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135	336.0
TH2_k127_6429890_11	it plays a direct role in the translocation of protons across the membrane	K02108	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526	319.0
TH2_k127_6429890_12	glycyl-radical enzyme activating protein family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099	316.0
TH2_k127_6429890_13	Major facilitator Superfamily	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134	316.0
TH2_k127_6429890_14	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	K02109	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000004418	256.0
TH2_k127_6429890_15	Serine threonine protein kinase	-	-	-	0.0000000000000000000000000000000000000000000000000000000003009	229.0
TH2_k127_6429890_16	Histone deacetylase domain	K04768	-	-	0.0000000000000000000000000000000000000000000000000000000004251	211.0
TH2_k127_6429890_17	Acetyltransferase (GNAT) domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000491	207.0
TH2_k127_6429890_18	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	K03664	-	-	0.0000000000000000000000000000000000000000000000000000000613	199.0
TH2_k127_6429890_19	-	-	-	-	0.00000000000000000000000000000000000000000000000000001434	197.0
TH2_k127_6429890_2	amino acid	K03294	-	-	3.089e-217	686.0
TH2_k127_6429890_20	Domain of unknown function	-	-	-	0.000000000000000000000000000000000000000000001363	175.0
TH2_k127_6429890_21	SRPBCC domain-containing protein	-	-	-	0.000000000000000000000000000000000000000000004699	167.0
TH2_k127_6429890_22	adenosylhomocysteine nucleosidase activity	K01239,K01243,K03716	-	3.2.2.1,3.2.2.9,4.1.99.14	0.0000000000000000000000000000000000000000000111	170.0
TH2_k127_6429890_23	Belongs to the complex I subunit 6 family	K00339	-	1.6.5.3	0.00000000000000000000000000000000000000000006528	165.0
TH2_k127_6429890_24	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00330	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	0.00000000000000000000000000000000000000001503	157.0
TH2_k127_6429890_25	Acetyltransferase (GNAT) domain	K03828	-	-	0.00000000000000000000000000000000001674	140.0
TH2_k127_6429890_26	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00340,K05576	-	1.6.5.3	0.00000000000000000000000000000001136	129.0
TH2_k127_6429890_27	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	K02110	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	0.000000000000000000000000005453	111.0
TH2_k127_6429890_28	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	0.000000000000000000001944	101.0
TH2_k127_6429890_29	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	0.000000000000002845	83.0
TH2_k127_6429890_3	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	K00342	-	1.6.5.3	1.131e-214	677.0
TH2_k127_6429890_31	Acetyltransferase (GNAT) domain	-	-	-	0.000000002405	64.0
TH2_k127_6429890_32	Endonuclease/Exonuclease/phosphatase family	-	-	-	0.000000005	67.0
TH2_k127_6429890_33	Cytochrome c	-	-	-	0.0003761	47.0
TH2_k127_6429890_4	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	K01928	-	6.3.2.13	1.571e-203	646.0
TH2_k127_6429890_5	Pyruvate formate lyase	K00656	-	2.3.1.54	1.442e-200	648.0
TH2_k127_6429890_6	Beta-eliminating lyase	-	-	-	9.495e-198	625.0
TH2_k127_6429890_7	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	K00342	-	1.6.5.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252	462.0
TH2_k127_6429890_8	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00343	-	1.6.5.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037	438.0
TH2_k127_6429890_9	metallophosphoesterase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144	360.0
TH2_k127_6513_0	Phosphoenolpyruvate synthase	K01007	-	2.7.9.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493	547.0
TH2_k127_6513_1	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	K01007	-	2.7.9.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836	501.0
TH2_k127_6513_2	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	K01491	-	1.5.1.5,3.5.4.9	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034	456.0
TH2_k127_6513_3	Pyruvate phosphate dikinase, PEP pyruvate binding	K01006,K01007	-	2.7.9.1,2.7.9.2	0.0000000000000000000007959	101.0
TH2_k127_6513_4	uridine kinase	-	-	-	0.000000000000000001129	94.0
TH2_k127_6518216_0	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	K02112	-	3.6.3.14	3.735e-244	760.0
TH2_k127_6518216_1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	K02115	-	-	0.00000000000000000000000000000000000000000000000000000000121	206.0
TH2_k127_6518216_2	Produces ATP from ADP in the presence of a proton gradient across the membrane	K02114	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	0.000000000000000000001526	95.0
TH2_k127_6613255_0	L-lactate permease	K03303	-	-	9.276e-199	632.0
TH2_k127_6613255_1	Oligopeptidase F	K08602	-	-	6.402e-196	629.0
TH2_k127_6613255_10	Phosphotransferase	-	-	-	0.0000000000000003026	89.0
TH2_k127_6613255_2	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	K00820	-	2.6.1.16	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079	543.0
TH2_k127_6613255_3	beta-galactosidase activity	K01190,K17624	-	3.2.1.23,3.2.1.97	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741	520.0
TH2_k127_6613255_4	secreted hydrolase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002988	286.0
TH2_k127_6613255_5	PFAM Cyclic nucleotide-binding	K10914,K21564	-	-	0.00000000000000000000000000000000000000000000000000000000001247	215.0
TH2_k127_6613255_6	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	0.000000000000000000000000000000000000000000000000000000001588	203.0
TH2_k127_6613255_7	Putative pyruvate format-lyase activating enzyme (DUF1786)	-	-	-	0.0000000000000000000000000000000000000000000002783	172.0
TH2_k127_6613255_8	Hemerythrin HHE cation binding domain	-	-	-	0.0000000000000000000000000000000000000000249	157.0
TH2_k127_6613255_9	Glyoxalase-like domain	K07032	-	-	0.0000000000000000000000000003794	118.0
TH2_k127_6649438_0	Thermophilic metalloprotease (M29)	K19689	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803	463.0
TH2_k127_6649438_1	Aldo Keto reductase	K07079	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000001855	275.0
TH2_k127_6649438_2	Uncharacterised protein family UPF0047	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000518	266.0
TH2_k127_6649438_3	carbohydrate transport	K02027	-	-	0.00000000000000000000000000000000000000000000000000000000000001344	221.0
TH2_k127_6649438_4	Ankyrin repeat	K06867	-	-	0.00000000000000000000000000000000000000000000007042	177.0
TH2_k127_6708470_0	diguanylate cyclase	-	-	-	0.00000000000000000000000000000000000000007823	163.0
TH2_k127_6708470_1	PFAM Sulfate transporter antisigma-factor antagonist STAS	K04749	-	-	0.000003532	55.0
TH2_k127_6719069_0	PFAM Na-Ca exchanger integrin-beta4	-	-	-	1.772e-280	922.0
TH2_k127_6719069_1	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	K03665	-	-	2.314e-199	631.0
TH2_k127_6719069_10	protein histidine kinase activity	-	-	-	0.00000000000000000000000000000000000001931	145.0
TH2_k127_6719069_11	Fibronectin type 3 domain	-	-	-	0.00000000000000000000000001782	129.0
TH2_k127_6719069_12	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	K03635,K21142	-	2.8.1.12	0.000000000000000005249	85.0
TH2_k127_6719069_14	-	-	-	-	0.00000001466	64.0
TH2_k127_6719069_2	Domain of unknown function(DUF2779)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614	527.0
TH2_k127_6719069_3	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	K09458	-	2.3.1.179	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299	439.0
TH2_k127_6719069_4	Provides the (R)-glutamate required for cell wall biosynthesis	K01776	-	5.1.1.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199	346.0
TH2_k127_6719069_5	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	K05896	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000009411	252.0
TH2_k127_6719069_6	PFAM glutamine amidotransferase class-I	K07010	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000004583	245.0
TH2_k127_6719069_7	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	K03635,K21142	-	2.8.1.12	0.000000000000000000000000000000000000000000000000000000000000000149	224.0
TH2_k127_6719069_8	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	K03637	-	4.6.1.17	0.00000000000000000000000000000000000000000000000000000004543	210.0
TH2_k127_6719069_9	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	K02884	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.000000000000000000000000000000000000002957	149.0
TH2_k127_6734937_0	FGGY family of carbohydrate kinases, C-terminal domain	K00854	-	2.7.1.17	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409	520.0
TH2_k127_6734937_1	C4-dicarboxylate anaerobic carrier	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244	389.0
TH2_k127_674287_0	pyruvate phosphate dikinase, PEP	K01007	-	2.7.9.2	7.271e-214	693.0
TH2_k127_674287_1	PFAM cell divisionFtsK SpoIIIE	K03466	-	-	8.603e-212	680.0
TH2_k127_674287_10	Protein of unknown function DUF58	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031	392.0
TH2_k127_674287_11	MFS_1 like family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355	371.0
TH2_k127_674287_12	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	K13292	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263	333.0
TH2_k127_674287_13	Stage II sporulation protein M	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885	346.0
TH2_k127_674287_14	diguanylate cyclase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224	334.0
TH2_k127_674287_15	PFAM ABC transporter related	K01990	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364	317.0
TH2_k127_674287_16	COG0477 Permeases of the major facilitator superfamily	K08153	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163	310.0
TH2_k127_674287_17	transferase activity, transferring acyl groups	K15520	-	2.3.1.189	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704	307.0
TH2_k127_674287_18	PFAM RNA binding S1 domain protein	K02945,K03527	-	1.17.7.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427	300.0
TH2_k127_674287_19	transferase activity, transferring acyl groups	K15520	-	2.3.1.189	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001664	296.0
TH2_k127_674287_2	N-terminal 7TM region of histidine kinase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614	569.0
TH2_k127_674287_20	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005126	281.0
TH2_k127_674287_21	NAD-dependent epimerase dehydratase	K07071	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000001051	270.0
TH2_k127_674287_22	HNH endonuclease	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000002016	263.0
TH2_k127_674287_23	aromatic amino acid beta-eliminating lyase threonine aldolase	K01620	-	4.1.2.48	0.00000000000000000000000000000000000000000000000000000000000000000000000003416	256.0
TH2_k127_674287_24	Aminoglycoside phosphotransferase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000006751	252.0
TH2_k127_674287_25	Putative cyclase	K07130	-	3.5.1.9	0.0000000000000000000000000000000000000000000000000000000000000000009682	234.0
TH2_k127_674287_26	CDP-alcohol phosphatidyltransferase	K00995	-	2.7.8.5	0.0000000000000000000000000000000000000000000000000000000000000007262	225.0
TH2_k127_674287_27	Two component transcriptional regulator, LuxR family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000005722	220.0
TH2_k127_674287_28	Two component transcriptional regulator, LuxR family	-	-	-	0.00000000000000000000000000000000000000000000000000000000009183	211.0
TH2_k127_674287_29	imidazolonepropionase activity	K15358	-	3.5.2.18	0.0000000000000000000000000000000000000000000000000000001231	217.0
TH2_k127_674287_3	collagen metabolic process	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233	504.0
TH2_k127_674287_30	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	0.000000000000000000000000000000000000000000000005055	187.0
TH2_k127_674287_31	Restriction endonuclease	K07448	-	-	0.000000000000000000000000000000000000000000000005494	182.0
TH2_k127_674287_32	Metallo-beta-lactamase superfamily	K00784	-	3.1.26.11	0.000000000000000000000000000000000000000000004911	172.0
TH2_k127_674287_33	acetyltransferase	K06889,K19273	-	-	0.00000000000000000000000000000000000001113	151.0
TH2_k127_674287_34	-	-	-	-	0.0000000000000000000000000000000000001192	151.0
TH2_k127_674287_35	Pfam:Arch_ATPase	-	-	-	0.00000000000000000000000000000000002051	150.0
TH2_k127_674287_36	Histidine kinase	-	-	-	0.00000000000000000000000000000000003432	155.0
TH2_k127_674287_37	phosphorelay signal transduction system	-	-	-	0.00000000000000000000000000000001854	133.0
TH2_k127_674287_38	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	0.0000000000000000000000000000005225	131.0
TH2_k127_674287_39	Domain of unknown function (DUF309)	K09763	-	-	0.000000000000000000000000000004597	128.0
TH2_k127_674287_4	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	K02549	-	4.2.1.113	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218	459.0
TH2_k127_674287_40	Tetratricopeptide repeat	-	-	-	0.00000000000000000000000000005285	136.0
TH2_k127_674287_41	-	-	-	-	0.0000000000000000000000000003684	117.0
TH2_k127_674287_42	Belongs to the MraZ family	K03925	-	-	0.0000000000000000000000000005645	118.0
TH2_k127_674287_43	sequence-specific DNA binding	K15539	-	-	0.0000000000000000000003424	104.0
TH2_k127_674287_44	pyridoxamine 5'-phosphate oxidase	-	-	-	0.00000000000000000001036	98.0
TH2_k127_674287_45	Domain of unknown function (DUF4129)	-	-	-	0.000000000000000001069	97.0
TH2_k127_674287_46	TPR repeat	-	-	-	0.000000000002529	81.0
TH2_k127_674287_47	Adenylate cyclase	K01768	-	4.6.1.1	0.00000000002968	76.0
TH2_k127_674287_48	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	0.0000000001216	64.0
TH2_k127_674287_49	CAAX protease self-immunity	K07052	-	-	0.000000001202	69.0
TH2_k127_674287_5	PFAM ATPase associated with various cellular activities, AAA_3	K03924	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022	438.0
TH2_k127_674287_50	AAA ATPase domain	-	-	-	0.000000002536	71.0
TH2_k127_674287_51	peptidyl-tyrosine sulfation	-	-	-	0.0000005961	62.0
TH2_k127_674287_52	beta-lactamase	-	-	-	0.000001952	52.0
TH2_k127_674287_53	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	0.000004854	56.0
TH2_k127_674287_54	Pfam:DUF2029	-	-	-	0.000006289	58.0
TH2_k127_674287_55	PFAM Protein kinase domain	-	-	-	0.00002544	54.0
TH2_k127_674287_56	tetratricopeptide repeat	-	-	-	0.0003202	53.0
TH2_k127_674287_6	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	K01866	-	6.1.1.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777	437.0
TH2_k127_674287_7	response regulator, receiver	K02482	-	2.7.13.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624	452.0
TH2_k127_674287_8	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	K03783	-	2.4.2.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332	389.0
TH2_k127_674287_9	Bacterial capsule synthesis protein PGA_cap	K07282	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112	401.0
TH2_k127_6788276_0	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	K00198	-	1.2.7.4	2.759e-277	865.0
TH2_k127_6788276_1	Parallel beta-helix repeats	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284	452.0
TH2_k127_6788276_10	4Fe-4S dicluster domain	K00196	-	-	0.000000000000000000000000000000000000000000000000000000000006147	218.0
TH2_k127_6788276_11	metallopeptidase activity	-	-	-	0.000000000000000000000000000000000000000000000000000000000008839	235.0
TH2_k127_6788276_12	-	-	-	-	0.00000000000000000000000000000000000000000008805	185.0
TH2_k127_6788276_14	Subtilase family	K13274,K14645	-	-	0.0000000000000000000000000000000009464	151.0
TH2_k127_6788276_15	WD40-like Beta Propeller Repeat	-	-	-	0.00000000000000000000000002743	128.0
TH2_k127_6788276_16	Staphylococcal nuclease homologues	-	-	-	0.000000000000000000000005148	120.0
TH2_k127_6788276_17	PFAM peptidase M23B	-	-	-	0.0000000000000000261	99.0
TH2_k127_6788276_2	Bacterial extracellular solute-binding proteins, family 5 Middle	K02035	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296	356.0
TH2_k127_6788276_3	Binding-protein-dependent transport system inner membrane component	K02033	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304	345.0
TH2_k127_6788276_4	Amidohydrolase family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782	353.0
TH2_k127_6788276_5	Binding-protein-dependent transport system inner membrane component	K02034	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624	339.0
TH2_k127_6788276_6	Pyridine nucleotide-disulphide oxidoreductase	K00362	-	1.7.1.15	0.000000000000000000000000000000000000000000000000000000000000000000000000000000006666	286.0
TH2_k127_6788276_7	TIGRFAM conserved repeat domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000405	306.0
TH2_k127_6788276_8	glucosidase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000004518	273.0
TH2_k127_6788276_9	regulation of response to stimulus	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000001841	256.0
TH2_k127_6796525_0	TIGRFAM DNA polymerase III, alpha subunit	K02337	-	2.7.7.7	0.0	1373.0
TH2_k127_6796525_1	Dehydrogenase E1 component	K00615	-	2.2.1.1	5.306e-307	960.0
TH2_k127_6796525_10	PFAM peptidase M3A and M3B, thimet oligopeptidase F	K08602	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942	598.0
TH2_k127_6796525_11	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	K03590	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492	567.0
TH2_k127_6796525_12	hydrogenase expression formation protein HypD	K04654	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225	549.0
TH2_k127_6796525_13	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925	562.0
TH2_k127_6796525_14	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	K01736	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329	537.0
TH2_k127_6796525_15	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	K03531	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892	534.0
TH2_k127_6796525_16	Domain of unknown function (DUF4445)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253	520.0
TH2_k127_6796525_17	Belongs to the D-alanine--D-alanine ligase family	K01921	-	6.3.2.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846	484.0
TH2_k127_6796525_18	Aldo/keto reductase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626	461.0
TH2_k127_6796525_19	SMART PUA domain containing protein	K06969	-	2.1.1.191	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427	460.0
TH2_k127_6796525_2	PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit	K14138	-	2.3.1.169	2.15e-268	846.0
TH2_k127_6796525_20	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	K03629	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834	452.0
TH2_k127_6796525_21	Tryptophanyl-tRNA synthetase	K01867	-	6.1.1.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658	442.0
TH2_k127_6796525_22	aminopeptidase activity	K01179,K01269	-	3.2.1.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537	431.0
TH2_k127_6796525_23	metal-dependent phosphohydrolase, HD sub domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008304	431.0
TH2_k127_6796525_24	hydrogenase expression formation protein HypE	K04655	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222	421.0
TH2_k127_6796525_25	PFAM DAHP synthetase I KDSA	K03856	-	2.5.1.54	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007658	421.0
TH2_k127_6796525_26	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	K00800	-	2.5.1.19	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505	427.0
TH2_k127_6796525_27	Catalytic domain of components of various dehydrogenase complexes	K00658	-	2.3.1.61	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266	396.0
TH2_k127_6796525_28	CO dehydrogenase acetyl-CoA synthase delta subunit	K00197	-	2.1.1.245	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409	396.0
TH2_k127_6796525_29	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	K01476,K01480	GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	3.5.3.1,3.5.3.11	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667	364.0
TH2_k127_6796525_3	Belongs to the carbamoyltransferase HypF family	K04656	-	-	7.948e-268	848.0
TH2_k127_6796525_30	PFAM luciferase family protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111	360.0
TH2_k127_6796525_31	Formate/nitrite transporter	K06212	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728	363.0
TH2_k127_6796525_32	Cell wall formation	K00075	-	1.3.1.98	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816	352.0
TH2_k127_6796525_33	Belongs to the HpcH HpaI aldolase family	K01630,K02510	-	4.1.2.20,4.1.2.52	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093	319.0
TH2_k127_6796525_34	one-carbon metabolic process	K00194,K00198	-	1.2.7.4,2.1.1.245	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976	319.0
TH2_k127_6796525_35	PFAM conserved	K07027	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828	312.0
TH2_k127_6796525_36	Phosphotransferase enzyme family	K18844	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133	301.0
TH2_k127_6796525_37	Redoxin	K11065	-	1.11.1.15	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004884	281.0
TH2_k127_6796525_38	FES	K10773	-	4.2.99.18	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000907	280.0
TH2_k127_6796525_39	Hydrogenase accessory protein HypB	K03189,K04652	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000009808	276.0
TH2_k127_6796525_4	COGs COG3533 conserved	K09955	-	-	4.557e-228	722.0
TH2_k127_6796525_40	Response regulator, receiver	K02487,K03407,K03413,K06596,K11526,K13490	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000004359	272.0
TH2_k127_6796525_41	CO dehydrogenase	K07321	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000001746	270.0
TH2_k127_6796525_42	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000304	283.0
TH2_k127_6796525_43	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	K03787	-	3.1.3.5	0.00000000000000000000000000000000000000000000000000000000000000000000000002466	260.0
TH2_k127_6796525_44	Glutamine amidotransferase of anthranilate synthase	K01658,K01664	-	2.6.1.85,4.1.3.27	0.000000000000000000000000000000000000000000000000000000000000000000000001562	249.0
TH2_k127_6796525_45	Methylenetetrahydrofolate reductase	K00297,K00547	-	1.5.1.20,2.1.1.10	0.0000000000000000000000000000000000000000000000000000000000000000000004854	257.0
TH2_k127_6796525_46	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	K01462	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	0.000000000000000000000000000000000000000000000000000000000000000000002018	239.0
TH2_k127_6796525_47	Inositol monophosphatase family	K01092	-	3.1.3.25	0.000000000000000000000000000000000000000000000000000000000000000000003941	243.0
TH2_k127_6796525_48	response regulator, receiver	K02479	-	-	0.000000000000000000000000000000000000000000000000000000000000000000004155	241.0
TH2_k127_6796525_49	PFAM Cobyrinic acid ac-diamide synthase	K07321	-	-	0.0000000000000000000000000000000000000000000000000000000000000000001439	238.0
TH2_k127_6796525_5	Pyridine nucleotide-disulphide oxidoreductase dimerisation region	K00382	-	1.8.1.4	1.05e-220	692.0
TH2_k127_6796525_50	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000005995	249.0
TH2_k127_6796525_51	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	K03469	-	3.1.26.4	0.00000000000000000000000000000000000000000000000000000000000000492	223.0
TH2_k127_6796525_52	histidine kinase HAMP region domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000003971	236.0
TH2_k127_6796525_53	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	K03387	-	-	0.0000000000000000000000000000000000000000000000000000000000006173	222.0
TH2_k127_6796525_54	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	K00014	-	1.1.1.25	0.0000000000000000000000000000000000000000000000000000000000006478	220.0
TH2_k127_6796525_55	phosphorelay signal transduction system	K07670	-	-	0.000000000000000000000000000000000000000000000000000000000006915	216.0
TH2_k127_6796525_56	Uracil-DNA glycosylase	K21929	-	3.2.2.27	0.00000000000000000000000000000000000000000000000000000001503	205.0
TH2_k127_6796525_57	Methyltransferase domain	-	-	-	0.00000000000000000000000000000000000000000000000000000001557	205.0
TH2_k127_6796525_58	Nucleotidyltransferase domain	-	-	-	0.0000000000000000000000000000000000000000000000001177	187.0
TH2_k127_6796525_59	PFAM dihydropteroate synthase, DHPS	K15023	-	2.1.1.258	0.0000000000000000000000000000000000000000000000002458	187.0
TH2_k127_6796525_6	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	K00198	-	1.2.7.4	8.597e-220	700.0
TH2_k127_6796525_60	NADPH-dependent FMN reductase	-	-	-	0.000000000000000000000000000000000000000000000001265	180.0
TH2_k127_6796525_61	PFAM Rhodanese domain protein	-	-	-	0.00000000000000000000000000000000000000000000004491	173.0
TH2_k127_6796525_62	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	0.00000000000000000000000000000000000000000000005343	176.0
TH2_k127_6796525_63	acetyltransferase	K00621	-	2.3.1.4	0.00000000000000000000000000000000000000000003852	173.0
TH2_k127_6796525_64	PFAM thioesterase superfamily protein	K07107	-	-	0.00000000000000000000000000000000000000000007729	163.0
TH2_k127_6796525_65	Acetyltransferase (GNAT) domain	-	-	-	0.0000000000000000000000000000000000000000001709	165.0
TH2_k127_6796525_66	membrane	-	-	-	0.00000000000000000000000000000000000000004941	159.0
TH2_k127_6796525_67	PFAM GCN5-related N-acetyltransferase	-	-	-	0.0000000000000000000000000000000000000000837	154.0
TH2_k127_6796525_68	Acetyltransferase (GNAT) domain	-	-	-	0.0000000000000000000000000000000000000002285	156.0
TH2_k127_6796525_69	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	0.0000000000000000000000000000000000000009867	149.0
TH2_k127_6796525_7	Malic enzyme, NAD binding domain	K00027,K00029	-	1.1.1.38,1.1.1.40	5.748e-195	619.0
TH2_k127_6796525_70	Domain of unknown function DUF302	-	-	-	0.000000000000000000000000000000000000005771	149.0
TH2_k127_6796525_71	Dienelactone hydrolase	-	-	-	0.00000000000000000000000000000000000008144	151.0
TH2_k127_6796525_72	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	K01921,K03589	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	6.3.2.4	0.00000000000000000000000000000000002616	147.0
TH2_k127_6796525_73	Probably plays a role in a hydrogenase nickel cofactor insertion step	K04651	-	-	0.0000000000000000000000000000000004862	134.0
TH2_k127_6796525_74	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	0.000000000000000000000000000000003292	139.0
TH2_k127_6796525_75	Serine aminopeptidase, S33	-	-	-	0.000000000000000000000000000000008568	137.0
TH2_k127_6796525_76	PFAM Abortive infection protein	-	-	-	0.000000000000000000000000000002426	131.0
TH2_k127_6796525_77	Belongs to the thioredoxin family	K03671	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	0.00000000000000000000000000002418	122.0
TH2_k127_6796525_78	PFAM hydrogenase expression formation protein (HUPF HYPC)	K04653	-	-	0.000000000000000000000000005453	111.0
TH2_k127_6796525_79	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	0.0000000000000000000000002337	111.0
TH2_k127_6796525_8	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	5.814e-195	614.0
TH2_k127_6796525_80	response regulator, receiver	-	-	-	0.0000000000000000000000008149	108.0
TH2_k127_6796525_81	Domain of unknown function (DUF3786)	-	-	-	0.0000000000000000000001326	106.0
TH2_k127_6796525_82	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	0.00000000001841	73.0
TH2_k127_6796525_83	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	K10697	-	-	0.00000000003865	68.0
TH2_k127_6796525_86	glyoxalase bleomycin resistance protein dioxygenase	K06996	-	-	0.00001308	52.0
TH2_k127_6796525_87	CBS domain	-	-	-	0.00003972	53.0
TH2_k127_6796525_89	4Fe-4S dicluster domain	K03390	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	0.0002281	47.0
TH2_k127_6796525_9	Transcriptional activator domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642	623.0
TH2_k127_6805403_0	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	K11618	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005712	289.0
TH2_k127_6805403_1	Histidine kinase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000005985	238.0
TH2_k127_6805403_2	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	0.00007865	48.0
TH2_k127_6815405_0	dead DEAH box helicase	K17675	-	3.6.4.13	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145	481.0
TH2_k127_6815405_2	Heparanase	K07964	-	3.2.1.166	0.0003284	46.0
TH2_k127_6816960_0	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	1.122e-197	622.0
TH2_k127_6816960_1	Trehalose utilisation	-	-	-	0.000002576	55.0
TH2_k127_6827738_0	PFAM ATP-binding region ATPase domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000001693	275.0
TH2_k127_6827738_1	hydrolase activity, acting on ester bonds	-	-	-	0.000000000000000000000000000000000000000000000000000000007727	210.0
TH2_k127_6827738_2	Methyltransferase domain	-	-	-	0.00000000000000000000000000000000000000000000000000000006222	211.0
TH2_k127_6827738_3	alpha beta	K06889	-	-	0.0000000000000000006766	96.0
TH2_k127_6827738_4	COG1073 Hydrolases of the alpha beta superfamily	K06889	-	-	0.0000000000000771	76.0
TH2_k127_6827738_5	regulator	K07667	-	-	0.0000000001979	62.0
TH2_k127_6830551_0	hydrolase activity, acting on ester bonds	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000003204	236.0
TH2_k127_6830551_1	Methyltransferase domain	-	-	-	0.000000000000000000000000000000000000004397	150.0
TH2_k127_6830551_2	BAAT / Acyl-CoA thioester hydrolase C terminal	K06889	-	-	0.000000000000000000000000000000007992	142.0
TH2_k127_6830551_3	BAAT / Acyl-CoA thioester hydrolase C terminal	K06889	-	-	0.0000000000000000000000000000001923	138.0
TH2_k127_6842347_0	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	K03555	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	0.0	1178.0
TH2_k127_6842347_1	PFAM NHL repeat containing protein	-	-	-	1.177e-303	970.0
TH2_k127_6842347_10	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	K00772	-	2.4.2.28	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802	402.0
TH2_k127_6842347_11	Protein of unknown function (DUF521)	K09123	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013	407.0
TH2_k127_6842347_12	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	K01834	-	5.4.2.11	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899	369.0
TH2_k127_6842347_13	Belongs to the FPP GGPP synthase family	K00805,K02523	-	2.5.1.30,2.5.1.90	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198	356.0
TH2_k127_6842347_14	Stage II sporulation	K07315	-	3.1.3.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206	351.0
TH2_k127_6842347_15	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	K06941	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329	347.0
TH2_k127_6842347_16	Formate/nitrite transporter	K06212	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814	323.0
TH2_k127_6842347_17	Lysine-specific metallo-endopeptidase	K08646	-	3.4.24.20	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348	325.0
TH2_k127_6842347_18	PFAM deoxynucleoside kinase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482	315.0
TH2_k127_6842347_19	Bacterial extracellular solute-binding proteins, family 5 Middle	K02035	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434	330.0
TH2_k127_6842347_2	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	K15987	-	3.6.1.1	1.85e-299	938.0
TH2_k127_6842347_20	PFAM LmbE family protein	K18455	-	3.5.1.115	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657	306.0
TH2_k127_6842347_21	integral membrane protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062	312.0
TH2_k127_6842347_22	extracellular matrix structural constituent	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088	317.0
TH2_k127_6842347_23	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	K02003	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164	300.0
TH2_k127_6842347_24	Putative peptidoglycan binding domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731	302.0
TH2_k127_6842347_25	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	K04564	-	1.15.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881	297.0
TH2_k127_6842347_26	glycerophosphodiester transmembrane transport	K02026	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000002002	281.0
TH2_k127_6842347_27	PFAM Haloacid dehalogenase domain protein hydrolase	K01101	-	3.1.3.41	0.0000000000000000000000000000000000000000000000000000000000000000005533	237.0
TH2_k127_6842347_28	EamA-like transporter family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000006156	239.0
TH2_k127_6842347_29	Belongs to the pseudouridine synthase RsuA family	K06178,K06181	-	5.4.99.20,5.4.99.22	0.0000000000000000000000000000000000000000000000000000000000000002627	226.0
TH2_k127_6842347_3	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	K01874	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	6.027e-269	841.0
TH2_k127_6842347_30	hydrolase, TatD	K03424	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	0.00000000000000000000000000000000000000000000000000000000000003831	224.0
TH2_k127_6842347_31	Serine threonine protein kinase	-	-	-	0.00000000000000000000000000000000000000000000000000000000001764	232.0
TH2_k127_6842347_32	Response regulator, receiver	K02487,K03407,K03413,K06596,K11526,K13490	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	0.00000000000000000000000000000000000000000000000000000000006996	210.0
TH2_k127_6842347_33	Prolyl-tRNA synthetase	K03976	-	-	0.0000000000000000000000000000000000000000000000000000004068	197.0
TH2_k127_6842347_34	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000003788	189.0
TH2_k127_6842347_35	SpoU rRNA Methylase family	-	-	-	0.00000000000000000000000000000000000000000004743	168.0
TH2_k127_6842347_36	metal-binding, possibly nucleic acid-binding protein	K07040	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	0.0000000000000000000000000000000000000000001204	164.0
TH2_k127_6842347_38	-	-	-	-	0.0000000000000000000000000000000000000000371	172.0
TH2_k127_6842347_39	Binding-protein-dependent transport system inner membrane component	-	-	-	0.00000000000000000000000000000000000000009438	162.0
TH2_k127_6842347_4	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	K01840	-	5.4.2.8	3.156e-227	711.0
TH2_k127_6842347_40	sh3 domain protein	K01448	-	3.5.1.28	0.0000000000000000000000000000000000006272	148.0
TH2_k127_6842347_41	PFAM Forkhead-associated protein	-	-	-	0.0000000000000000000000001296	111.0
TH2_k127_6842347_42	TIGRFAM RNA polymerase sigma factor, sigma-70 family	K03088	-	-	0.00000000000000000000000203	110.0
TH2_k127_6842347_43	PFAM Forkhead-associated protein	-	-	-	0.000000000000000000000005341	112.0
TH2_k127_6842347_44	sh3 domain protein	K01448	-	3.5.1.28	0.00000000000000000000001526	113.0
TH2_k127_6842347_45	3-demethylubiquinone-9 3-methyltransferase	-	-	-	0.00000000000000000000007397	100.0
TH2_k127_6842347_46	protein maturation	K13628	-	-	0.00000000000000000000009953	102.0
TH2_k127_6842347_47	Protein of unknown function DUF126	-	-	-	0.000000000000000000000352	109.0
TH2_k127_6842347_48	translation initiation factor activity	-	-	-	0.000000000000000000001626	99.0
TH2_k127_6842347_5	Belongs to the SEDS family	-	-	-	1.546e-208	674.0
TH2_k127_6842347_51	Bacterial extracellular solute-binding proteins, family 5 Middle	K02035	-	-	0.000000000000001948	91.0
TH2_k127_6842347_52	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	K01358	-	3.4.21.92	0.000000000000004366	76.0
TH2_k127_6842347_53	3-demethylubiquinone-9 3-methyltransferase	-	-	-	0.000000000000005147	77.0
TH2_k127_6842347_54	-	-	-	-	0.0000000000000471	78.0
TH2_k127_6842347_55	Cupin 2, conserved barrel domain protein	-	-	-	0.000000000005994	69.0
TH2_k127_6842347_56	PFAM regulatory protein AsnC Lrp family	-	-	-	0.000000000008008	68.0
TH2_k127_6842347_57	metal cluster binding	K06940	-	-	0.00000000001078	72.0
TH2_k127_6842347_58	CarD-like/TRCF domain	K07736	-	-	0.00000000001686	71.0
TH2_k127_6842347_59	adenosylcobinamide amidohydrolase	-	-	-	0.000000006529	63.0
TH2_k127_6842347_6	AAA ATPase domain	K01768	-	4.6.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195	545.0
TH2_k127_6842347_60	cellular water homeostasis	K03442,K22044	-	-	0.00000005599	63.0
TH2_k127_6842347_61	-	-	-	-	0.0000004914	61.0
TH2_k127_6842347_62	fOG TPR repeat	-	-	-	0.00000144	62.0
TH2_k127_6842347_63	-	-	-	-	0.000003599	53.0
TH2_k127_6842347_64	Pyridoxamine 5'-phosphate oxidase	-	-	-	0.00000565	54.0
TH2_k127_6842347_65	Bacterial SH3 domain	-	-	-	0.00005759	54.0
TH2_k127_6842347_66	Cell wall hydrolase	K01449	-	3.5.1.28	0.0002118	53.0
TH2_k127_6842347_7	Cys/Met metabolism PLP-dependent enzyme	K01739	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416	455.0
TH2_k127_6842347_8	MacB-like periplasmic core domain	K02004	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961	446.0
TH2_k127_6842347_9	Polysaccharide biosynthesis C-terminal domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653	430.0
TH2_k127_6852772_0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	K03043	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	0.0	2059.0
TH2_k127_6852772_1	Belongs to the PEP-utilizing enzyme family	K01006	-	2.7.9.1	0.0	1396.0
TH2_k127_6852772_10	acetyl-CoA carboxylase	K01961	-	6.3.4.14,6.4.1.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384	573.0
TH2_k127_6852772_11	PFAM Transketolase central region	K00162,K11381,K21417	-	1.2.4.1,1.2.4.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455	559.0
TH2_k127_6852772_12	Extracellular solute-binding protein	K02055,K11069	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749	523.0
TH2_k127_6852772_13	PFAM peptidase M4 thermolysin	K08603	-	3.4.24.27	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217	491.0
TH2_k127_6852772_14	PFAM major facilitator superfamily MFS_1	K06902	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484	484.0
TH2_k127_6852772_15	Pyridoxal-phosphate dependent enzyme	K01697,K01738	-	2.5.1.47,4.2.1.22	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676	483.0
TH2_k127_6852772_16	ThiF family	K21029,K21147	-	2.7.7.80,2.8.1.11	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876	471.0
TH2_k127_6852772_17	PFAM Aminotransferase class I and II	K00812	-	2.6.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086	463.0
TH2_k127_6852772_18	ATPase activity	K02052,K11072	-	3.6.3.31	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041	458.0
TH2_k127_6852772_19	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	K00161	-	1.2.4.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463	453.0
TH2_k127_6852772_2	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	K02355	-	-	0.0	1074.0
TH2_k127_6852772_20	acyl-CoA dehydrogenase	K00248,K00249	-	1.3.8.1,1.3.8.7	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856	434.0
TH2_k127_6852772_21	PFAM Polynucleotide adenylyltransferase region	K00970,K00974	-	2.7.7.19,2.7.7.72	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243	395.0
TH2_k127_6852772_22	PFAM binding-protein-dependent transport systems inner membrane component	K02054,K11071	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627	376.0
TH2_k127_6852772_23	Belongs to the dCTP deaminase family	K01494	-	3.5.4.13	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524	345.0
TH2_k127_6852772_24	ABC transporter (permease)	K02053	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514	337.0
TH2_k127_6852772_25	Receptor family ligand binding region	K01999	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077	363.0
TH2_k127_6852772_26	PFAM catalytic domain of components of various dehydrogenase complexes	K00627	-	2.3.1.12	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008	327.0
TH2_k127_6852772_27	Zinc-binding dehydrogenase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216	320.0
TH2_k127_6852772_28	Histone deacetylase domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041	304.0
TH2_k127_6852772_29	CAAX protease self-immunity	K07052	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001343	291.0
TH2_k127_6852772_3	elongation factor Tu domain 2 protein	K02355	-	-	7.614e-296	921.0
TH2_k127_6852772_30	PFAM thymidine kinase	K00857	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006264	289.0
TH2_k127_6852772_31	PFAM Glycerophosphoryl diester phosphodiesterase	K01126	-	3.1.4.46	0.0000000000000000000000000000000000000000000000000000000000000000000000000000004596	274.0
TH2_k127_6852772_32	Alcohol dehydrogenase GroES-like domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000002359	276.0
TH2_k127_6852772_33	Belongs to the purine pyrimidine phosphoribosyltransferase family	K00760	-	2.4.2.8	0.0000000000000000000000000000000000000000000000000000000000000000000000000009647	259.0
TH2_k127_6852772_34	PFAM Metallo-beta-lactamase superfamily	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000006354	252.0
TH2_k127_6852772_35	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	K02950	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000001548	243.0
TH2_k127_6852772_36	solute-binding protein	K10117	-	-	0.0000000000000000000000000000000000000000000000000000000000000001474	253.0
TH2_k127_6852772_37	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	K02992	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.0000000000000000000000000000000000000000000000000000000000000001634	224.0
TH2_k127_6852772_39	Major Facilitator Superfamily	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000364	235.0
TH2_k127_6852772_4	PFAM carboxyl transferase	K01966	-	2.1.3.15,6.4.1.3	4.854e-246	769.0
TH2_k127_6852772_40	D-aminopeptidase	K16203	-	-	0.000000000000000000000000000000000000000000000000000000000000007278	225.0
TH2_k127_6852772_41	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000886	209.0
TH2_k127_6852772_42	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	-	-	-	0.0000000000000000000000000000000000000000000000000000008179	201.0
TH2_k127_6852772_43	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	0.00000000000000000000000000000000000000000000000000001088	212.0
TH2_k127_6852772_44	ubiE/COQ5 methyltransferase family	K03183	-	2.1.1.163,2.1.1.201	0.0000000000000000000000000000000000000000000000000002609	192.0
TH2_k127_6852772_45	Binds the 23S rRNA	K02909	-	-	0.00000000000000000000000000000000000000000000000001409	184.0
TH2_k127_6852772_46	Acetyltransferase (GNAT) family	-	-	-	0.00000000000000000000000000000000000000000000000006245	184.0
TH2_k127_6852772_47	PFAM Transposase DDE domain	-	-	-	0.000000000000000000000000000000000000000000000006888	173.0
TH2_k127_6852772_48	Nitroreductase family	-	-	-	0.00000000000000000000000000000000000000000000007101	179.0
TH2_k127_6852772_49	methyltransferase activity	K00569	-	2.1.1.67	0.000000000000000000000000000000000000000000103	166.0
TH2_k127_6852772_5	Glycosyl hydrolases family 38 C-terminal domain	K01191	-	3.2.1.24	3.942e-230	739.0
TH2_k127_6852772_50	CYTH domain	K05873	-	4.6.1.1	0.0000000000000000000000000000000000000000001549	166.0
TH2_k127_6852772_51	helicase activity	K06877	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	0.0000000000000000000000000000000000000000004627	165.0
TH2_k127_6852772_52	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	0.000000000000000000000000000000000000009922	159.0
TH2_k127_6852772_53	Nitroreductase family	-	-	-	0.00000000000000000000000000000000000001356	149.0
TH2_k127_6852772_54	Acyl-transferase	-	-	-	0.0000000000000000000000000000000000007994	152.0
TH2_k127_6852772_55	Ribosomal L27 protein	K02899	-	-	0.0000000000000000000000000000000000164	138.0
TH2_k127_6852772_56	-	-	-	-	0.0000000000000000000000000000000006331	144.0
TH2_k127_6852772_57	TIGRFAM competence protein ComEA helix-hairpin-helix	K02237	-	-	0.000000000000000000000000000000001189	136.0
TH2_k127_6852772_58	phosphorelay signal transduction system	-	-	-	0.000000000000000000000000000000001266	135.0
TH2_k127_6852772_59	This protein binds to 23S rRNA in the presence of protein L20	K02888	GO:0003674,GO:0003735,GO:0005198	-	0.000000000000000000000000000000003833	134.0
TH2_k127_6852772_6	DNA helicase	-	-	-	2.556e-211	677.0
TH2_k127_6852772_60	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	0.00000000000000000000000000002056	124.0
TH2_k127_6852772_61	CoA carboxylase activity	K01965,K02160	-	6.4.1.3	0.00000000000000000000000000004622	122.0
TH2_k127_6852772_62	PFAM Transposase DDE domain	-	-	-	0.000000000000000000000000049	110.0
TH2_k127_6852772_63	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	K01356	-	3.4.21.88	0.0000000000000000000008776	103.0
TH2_k127_6852772_65	domain protein	K21687	-	-	0.00000000000000000006803	102.0
TH2_k127_6852772_66	Acetyltransferase (GNAT) domain	-	-	-	0.00000000000000953	79.0
TH2_k127_6852772_67	PFAM thiamineS protein	K03636	-	-	0.000000001106	62.0
TH2_k127_6852772_68	-	-	-	-	0.00000001649	63.0
TH2_k127_6852772_69	STAS domain	K04749,K06378	-	-	0.00000008886	58.0
TH2_k127_6852772_7	UvrD-like helicase C-terminal domain	K03657	-	3.6.4.12	1.373e-201	653.0
TH2_k127_6852772_70	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	0.0000001036	65.0
TH2_k127_6852772_71	PFAM Transposase DDE domain	-	-	-	0.00000027	51.0
TH2_k127_6852772_74	Bacterial membrane protein YfhO	-	-	-	0.000001723	61.0
TH2_k127_6852772_75	Domain of unknown function (DUF4870)	K09940	-	-	0.000006427	58.0
TH2_k127_6852772_76	PFAM Transposase DDE domain	-	-	-	0.00001323	47.0
TH2_k127_6852772_77	Belongs to the anti-sigma-factor antagonist family	K06378	-	-	0.00003261	50.0
TH2_k127_6852772_8	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	K02358	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354	595.0
TH2_k127_6852772_9	Formiminotransferase domain, N-terminal subdomain	K00603,K13990	-	2.1.2.5,4.3.1.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408	595.0
TH2_k127_6853776_0	acyl-CoA dehydrogenase	-	-	-	1.174e-283	880.0
TH2_k127_6853776_1	PFAM carboxyl transferase	K01969,K15052	-	2.1.3.15,6.4.1.3,6.4.1.4	9.05e-262	814.0
TH2_k127_6853776_10	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	K03893	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051	366.0
TH2_k127_6853776_11	PFAM sodium calcium exchanger membrane region	K07301	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303	353.0
TH2_k127_6853776_12	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	K01918	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199	346.0
TH2_k127_6853776_13	PFAM extracellular solute-binding protein, family 5	K02035	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538	318.0
TH2_k127_6853776_14	acetyltransferase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145	304.0
TH2_k127_6853776_15	Citrate lyase	K11390	GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0019222,GO:0022607,GO:0030656,GO:0031323,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046872,GO:0046912,GO:0047777,GO:0050789,GO:0050794,GO:0051171,GO:0051193,GO:0051259,GO:0051260,GO:0062012,GO:0065003,GO:0065007,GO:0070206,GO:0070207,GO:0071840,GO:0106064,GO:1901401	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000008628	282.0
TH2_k127_6853776_16	PFAM MaoC domain protein dehydratase	K14449	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575	4.2.1.148	0.0000000000000000000000000000000000000000000000000000000000002124	215.0
TH2_k127_6853776_17	EamA-like transporter family	-	-	-	0.000000000000000000000000000000000000000000000000002183	192.0
TH2_k127_6853776_18	DUF35 OB-fold domain, acyl-CoA-associated	K07068	-	-	0.000000000000000000000000000000000000000000000000004218	187.0
TH2_k127_6853776_19	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	K03282	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	0.0000000000000000000000000000000000000000000004135	169.0
TH2_k127_6853776_2	UvrD-like helicase C-terminal domain	K03657	-	3.6.4.12	1.205e-251	815.0
TH2_k127_6853776_20	Protein of unknown function (DUF1579)	-	-	-	0.0000000000000000000000000000000000003131	147.0
TH2_k127_6853776_21	thiolester hydrolase activity	K06889	-	-	0.00000000000000000000000000000000004179	145.0
TH2_k127_6853776_22	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	K03111	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576	-	0.00000000000000000000000000000001087	130.0
TH2_k127_6853776_23	Cyclic-di-AMP receptor	-	-	-	0.0000000000000000000000000001574	122.0
TH2_k127_6853776_24	mRNA catabolic process	-	-	-	0.0000000000000000000005656	102.0
TH2_k127_6853776_25	CoA carboxylase activity	K01965	-	6.4.1.3	0.0000000000000000009552	92.0
TH2_k127_6853776_26	-	-	-	-	0.00000000000008062	73.0
TH2_k127_6853776_27	SPFH domain Band 7 family	-	-	-	0.0000000000003275	80.0
TH2_k127_6853776_28	Cyclic-di-AMP receptor	-	-	-	0.000000000001128	71.0
TH2_k127_6853776_29	CBS domain	-	-	-	0.000000000005895	72.0
TH2_k127_6853776_3	Belongs to the thiolase family	K00626	-	2.3.1.9	6.27e-219	687.0
TH2_k127_6853776_30	-	-	-	-	0.0000004079	62.0
TH2_k127_6853776_31	Tetratricopeptide TPR_2 repeat protein	-	-	-	0.000006646	58.0
TH2_k127_6853776_4	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain	K04940	-	1.5.1.28	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457	589.0
TH2_k127_6853776_5	Carbamoyl-phosphate synthetase large chain domain protein	K01961,K01968,K11263	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115	563.0
TH2_k127_6853776_6	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	K10823	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236	461.0
TH2_k127_6853776_7	Belongs to the ABC transporter superfamily	K02031,K15583	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505	440.0
TH2_k127_6853776_8	cobalamin binding	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307	425.0
TH2_k127_6853776_9	Belongs to the N(4) N(6)-methyltransferase family	K00571,K00590	-	2.1.1.113,2.1.1.72	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903	412.0
TH2_k127_6855700_0	PFAM Cytochrome C assembly protein	K02198	-	-	8.912e-206	649.0
TH2_k127_6855700_1	subunit of a heme lyase	K02200	-	-	0.000000000000000000000000000002831	126.0
TH2_k127_6863014_0	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	K01870	-	6.1.1.5	0.0	1545.0
TH2_k127_6863014_1	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199	520.0
TH2_k127_6863014_2	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	K07141	-	2.7.7.76	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601	340.0
TH2_k127_6863014_3	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	K07141	-	2.7.7.76	0.0000000000000000000000000000000000000000000000000001658	192.0
TH2_k127_6863014_4	-	-	-	-	0.0000000000000000000000000000000000000000000004132	170.0
TH2_k127_6863014_5	Phosphate acyltransferases	K00655	-	2.3.1.51	0.000000000000000000000000000000000000000000006442	171.0
TH2_k127_6863014_6	Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP	K01004	-	2.7.8.24	0.00000000000000000000000000000000000000000009832	168.0
TH2_k127_6863014_7	FR47-like protein	-	-	-	0.000000000000000000000000007834	114.0
TH2_k127_6884847_0	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319	519.0
TH2_k127_6884847_1	Fatty acid desaturase	K10255	-	1.14.19.23,1.14.19.45	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659	409.0
TH2_k127_6884847_2	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	K00850	-	2.7.1.11	0.00000000000000000000000000000000000000000000000009813	180.0
TH2_k127_6910382_0	Short-chain dehydrogenase reductase SDR	K08679	-	5.1.3.6	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713	434.0
TH2_k127_6910382_1	PFAM glycosyl transferase group 1	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143	361.0
TH2_k127_6910382_2	polysaccharide biosynthetic process	K16694	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098	317.0
TH2_k127_6910382_3	RibD C-terminal domain	-	-	-	0.00000000001837	64.0
TH2_k127_692198_0	ABC-type multidrug transport system ATPase component	K01990	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000008827	259.0
TH2_k127_692198_1	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	0.0000000000000000000218	96.0
TH2_k127_6963193_0	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	K00951	-	2.7.6.5	1.732e-225	721.0
TH2_k127_6963193_1	Psort location Cytoplasmic, score 8.87	K01845	-	5.4.3.8	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219	492.0
TH2_k127_6963193_10	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	K02528	-	2.1.1.182	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189	335.0
TH2_k127_6963193_11	Response regulator receiver	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329	334.0
TH2_k127_6963193_12	Glycosyltransferase like family 2	K00721	-	2.4.1.83	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224	321.0
TH2_k127_6963193_13	PFAM Metallophosphoesterase	K07096	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376	311.0
TH2_k127_6963193_14	4-vinyl reductase, 4VR	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689	297.0
TH2_k127_6963193_15	Domain of unknown function (DUF348)	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000007948	279.0
TH2_k127_6963193_16	Cation efflux family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000002755	250.0
TH2_k127_6963193_17	PFAM Extracellular ligand-binding receptor	K01999	-	-	0.000000000000000000000000000000000000000000000000000000000000000001166	244.0
TH2_k127_6963193_18	Domain of unknown function (DUF4111)	K00984	-	2.7.7.47	0.000000000000000000000000000000000000000000000000000000000000000001166	237.0
TH2_k127_6963193_19	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	K03218,K03437	-	2.1.1.185	0.0000000000000000000000000000000000000000000000000000000000000002895	228.0
TH2_k127_6963193_2	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	K02836	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382	482.0
TH2_k127_6963193_20	PFAM RNA binding S1 domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000006065	218.0
TH2_k127_6963193_21	PFAM Roadblock LC7 family protein	K07131	-	-	0.00000000000000000000000000000000000000000000000000000000003944	208.0
TH2_k127_6963193_22	Belongs to the thioredoxin family	K03671	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	0.000000000000000000000000000000000000000000000000000000007276	199.0
TH2_k127_6963193_23	-	-	-	-	0.000000000000000000000000000000000000000000000000000005832	198.0
TH2_k127_6963193_24	Aminoacyl-tRNA editing domain	K03976	-	-	0.0000000000000000000000000000000000000000000000000002552	189.0
TH2_k127_6963193_25	Integrase catalytic	-	-	-	0.000000000000000000000000000000000000007525	152.0
TH2_k127_6963193_26	Rhomboid family	-	-	-	0.0000000000000000000000000000000000001085	150.0
TH2_k127_6963193_27	Blue (Type 1) copper domain protein	-	-	-	0.0000000000000000000000000000000000006336	143.0
TH2_k127_6963193_28	Cell envelope-related transcriptional attenuator domain	-	-	-	0.000000000000000000000000002087	125.0
TH2_k127_6963193_29	Antibiotic biosynthesis monooxygenase	-	-	-	0.00000000000000000000001523	103.0
TH2_k127_6963193_3	ABC transporter	K06158	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509	480.0
TH2_k127_6963193_30	sequence-specific DNA binding	-	-	-	0.000000000000000000004512	99.0
TH2_k127_6963193_31	DDE superfamily endonuclease	-	-	-	0.00000000000000000004956	97.0
TH2_k127_6963193_32	quinone binding	-	-	-	0.0000000000000000004173	92.0
TH2_k127_6963193_33	Integrase catalytic	-	-	-	0.000000000000000002258	90.0
TH2_k127_6963193_35	Tetratricopeptide TPR_2 repeat protein	-	-	-	0.0000000000002322	80.0
TH2_k127_6963193_36	Cyclic nucleotide-monophosphate binding domain	-	-	-	0.000000005765	64.0
TH2_k127_6963193_37	Phosphopantetheine attachment site	K02078	-	-	0.00002461	49.0
TH2_k127_6963193_38	-	-	-	-	0.0001078	46.0
TH2_k127_6963193_4	amino acid	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184	475.0
TH2_k127_6963193_5	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	K03110	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192	417.0
TH2_k127_6963193_6	PFAM AMP-dependent synthetase and ligase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025	397.0
TH2_k127_6963193_7	MoeA N-terminal region (domain I and II)	K03750	-	2.10.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000881	371.0
TH2_k127_6963193_8	ErfK ybiS ycfS ynhG family protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479	349.0
TH2_k127_6963193_9	Transposase DDE domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525	336.0
TH2_k127_7006768_0	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	K12574	-	-	4.101e-226	712.0
TH2_k127_7006768_1	PFAM ABC transporter related	K10112	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625	552.0
TH2_k127_7006768_2	HhH-GPD family	K03575	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596	340.0
TH2_k127_7006768_3	Beta-lactamase superfamily domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009596	301.0
TH2_k127_7006768_4	EamA-like transporter family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000001683	253.0
TH2_k127_7006768_5	-	-	-	-	0.000000000000000000000000000004861	122.0
TH2_k127_7006768_6	Transposase	-	-	-	0.00000000001934	68.0
TH2_k127_7043750_0	Nitroreductase family	-	-	-	0.00000000000000000000000000000000000001356	149.0
TH2_k127_7043750_1	Belongs to the UPF0337 (CsbD) family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	0.0000402	49.0
TH2_k127_7043750_2	LexA-binding, inner membrane-associated putative hydrolase	K07038	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.0001062	53.0
TH2_k127_7093574_0	Belongs to the ABC transporter superfamily	K02032,K10823	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003	544.0
TH2_k127_7093574_1	Belongs to the ABC transporter superfamily	K02031	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881	507.0
TH2_k127_7093574_10	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	K01489	-	3.5.4.5	0.0000000000000000000000000000000000000000000004526	169.0
TH2_k127_7093574_11	serine threonine protein kinase	K08884,K12132	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	0.0000000000000000000000002507	110.0
TH2_k127_7093574_12	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	K02035	-	-	0.000000000000000000008431	97.0
TH2_k127_7093574_13	HD domain	-	-	-	0.00000000003112	75.0
TH2_k127_7093574_14	-	-	-	-	0.0007598	50.0
TH2_k127_7093574_2	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	K04042	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057	421.0
TH2_k127_7093574_3	Serine threonine protein kinase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007629	416.0
TH2_k127_7093574_4	PFAM HD domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285	356.0
TH2_k127_7093574_5	Involved in DNA repair and RecF pathway recombination	K03584	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677	302.0
TH2_k127_7093574_6	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	K00573	-	2.1.1.77	0.000000000000000000000000000000000000000000000000000000000000006862	222.0
TH2_k127_7093574_7	-	-	-	-	0.000000000000000000000000000000000000000000000000000000000000045	233.0
TH2_k127_7093574_8	TIGRFAM geranylgeranyl reductase	K10960	-	1.3.1.111,1.3.1.83	0.0000000000000000000000000000000000000000000000003928	190.0
TH2_k127_7093574_9	Sulfatase-modifying factor enzyme 1	K18912	-	1.14.99.50	0.0000000000000000000000000000000000000000000004243	186.0
TH2_k127_7093647_0	PFAM extracellular solute-binding protein, family 5	K02035	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887	567.0
TH2_k127_7093647_1	PFAM binding-protein-dependent transport systems inner membrane component	K02033	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026	371.0
TH2_k127_7093647_2	PFAM extracellular solute-binding protein, family 5	K02035	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742	314.0
TH2_k127_7093647_3	PFAM binding-protein-dependent transport systems inner membrane component	K02034	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006934	295.0
TH2_k127_7093647_4	PFAM extracellular solute-binding protein, family 5	K02035	-	-	0.00000000000000002158	87.0
TH2_k127_7093647_5	Cytochrome C oxidase, cbb3-type, subunit III	K08738	-	-	0.0000000001818	70.0
TH2_k127_7117810_0	ABC transporter	K10441	-	3.6.3.17	2.367e-200	636.0
TH2_k127_7117810_1	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818	492.0
TH2_k127_7117810_2	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551	439.0
TH2_k127_7117810_3	Belongs to the binding-protein-dependent transport system permease family	K10440	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161	436.0
TH2_k127_7117810_4	inositol 2-dehydrogenase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264	420.0
TH2_k127_7117810_5	Belongs to the binding-protein-dependent transport system permease family	K02057,K10440	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218	414.0
TH2_k127_7117810_6	PFAM ROK family protein	K00845	-	2.7.1.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619	338.0
TH2_k127_7117810_7	DeoC/LacD family aldolase	K01619	-	4.1.2.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188	298.0
TH2_k127_7117810_8	Periplasmic binding protein domain	K10439	-	-	0.00000000000000000000000000000000000000000000000000000003818	198.0
TH2_k127_7117810_9	Phage integrase family	-	-	-	0.0000000001218	66.0
TH2_k127_7140795_0	-	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767	363.0
TH2_k127_7140795_1	Response regulator, receiver	K02487,K03407,K03413,K06596,K11526,K13490	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	0.000000000000000000000000000000000000001015	154.0
TH2_k127_7148911_0	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	K01876	-	6.1.1.12	6.759e-281	874.0
TH2_k127_7148911_1	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	K01875	-	6.1.1.11	1.157e-194	619.0
TH2_k127_7148911_10	peptidase M42 family protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124	425.0
TH2_k127_7148911_11	histidine kinase HAMP region domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646	411.0
TH2_k127_7148911_12	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187	388.0
TH2_k127_7148911_13	Two component transcriptional regulator, winged helix family	K07669	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655	376.0
TH2_k127_7148911_14	peptidase M42 family protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989	377.0
TH2_k127_7148911_15	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	K16329	-	4.2.1.70	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843	331.0
TH2_k127_7148911_16	heat shock protein binding	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168	340.0
TH2_k127_7148911_17	Belongs to the MEMO1 family	K06990	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262	323.0
TH2_k127_7148911_18	6-O-methylguanine DNA methyltransferase, DNA binding domain	K10778	-	2.1.1.63	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836	306.0
TH2_k127_7148911_19	PFAM Glycosyl transferase family 2	K14597	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000007907	277.0
TH2_k127_7148911_2	PFAM SMC domain protein	K03546	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229	600.0
TH2_k127_7148911_20	EamA-like transporter family	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000137	261.0
TH2_k127_7148911_21	Cellulose biosynthesis protein BcsQ	K02282	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000001407	266.0
TH2_k127_7148911_22	sigma-70 region 2 domain protein	K03088	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000848	241.0
TH2_k127_7148911_23	maltose binding	K02027,K15770	-	-	0.000000000000000000000000000000000000000000000000000000000000000000006051	252.0
TH2_k127_7148911_24	Phosphoribosyl transferase domain	K07101	-	-	0.0000000000000000000000000000000000000000000000000000000000000000002752	236.0
TH2_k127_7148911_26	Nudix hydrolase	-	-	-	0.0000000000000000000000000000000000000000000000000001157	191.0
TH2_k127_7148911_28	ferredoxin-NADP+ reductase activity	-	-	-	0.0000000000000000000000000000000000000000000000002195	183.0
TH2_k127_7148911_29	NapC/NirT cytochrome c family, N-terminal region	K15876	-	-	0.0000000000000000000000000000000000000000000000108	177.0
TH2_k127_7148911_3	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	K03385	-	1.7.2.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799	561.0
TH2_k127_7148911_30	PHP-associated	-	-	-	0.0000000000000000000000000000000000000000000007813	176.0
TH2_k127_7148911_31	DNA-templated transcription, initiation	K03088	-	-	0.0000000000000000000000000000000000000000001549	164.0
TH2_k127_7148911_32	-	-	-	-	0.00000000000000000000000000000000000000002067	160.0
TH2_k127_7148911_33	Peptidase family S51	-	-	-	0.000000000000000000000000000000000000008565	154.0
TH2_k127_7148911_34	Cyclic nucleotide-monophosphate binding domain	K10914	-	-	0.0000000000000000000000000000000002597	140.0
TH2_k127_7148911_35	lysozyme activity	K07273	-	-	0.000000000000000000000000000004046	135.0
TH2_k127_7148911_36	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	0.00000000000000000000000000002749	127.0
TH2_k127_7148911_37	'Cold-shock' DNA-binding domain	K03704	-	-	0.0000000000000000000000003804	105.0
TH2_k127_7148911_39	Copper chaperone PCu(A)C	K09796	-	-	0.00000000000000000000001146	106.0
TH2_k127_7148911_4	tRNA synthetase, class II (D, K and N)	K01893	-	6.1.1.22	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186	552.0
TH2_k127_7148911_40	Protein of unknown function (DUF456)	K09793	-	-	0.00000000000000000000001307	106.0
TH2_k127_7148911_41	Glycoside hydrolase	K07273	-	-	0.00000000000000000000005717	110.0
TH2_k127_7148911_43	-	-	-	-	0.00000000000000002349	95.0
TH2_k127_7148911_44	PFAM response regulator receiver	K02282	-	-	0.00000000000000127	89.0
TH2_k127_7148911_45	-	-	-	-	0.000000000000003413	82.0
TH2_k127_7148911_46	Pyridine nucleotide-disulphide oxidoreductase domain protein	-	-	-	0.0000000000001194	75.0
TH2_k127_7148911_47	AntiSigma factor	-	-	-	0.0000000000004387	79.0
TH2_k127_7148911_48	Protein of unknown function (DUF3592)	-	-	-	0.00000000001378	73.0
TH2_k127_7148911_49	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	0.00000000002236	75.0
TH2_k127_7148911_5	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	K04066	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711	565.0
TH2_k127_7148911_50	stress-induced mitochondrial fusion	K04066,K07037,K17266	-	-	0.00000000002294	77.0
TH2_k127_7148911_51	Lysin motif	-	-	-	0.0000000002327	73.0
TH2_k127_7148911_52	TadE-like protein	-	-	-	0.000008955	55.0
TH2_k127_7148911_53	Putative Flp pilus-assembly TadE/G-like	-	-	-	0.00006319	49.0
TH2_k127_7148911_54	ATP-grasp domain	-	-	-	0.000164	49.0
TH2_k127_7148911_55	domain, Protein	K11904,K12132	-	2.7.11.1	0.0007477	48.0
TH2_k127_7148911_6	Belongs to the class-II aminoacyl-tRNA synthetase family	K04567	-	6.1.1.6	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248	546.0
TH2_k127_7148911_7	glutamine synthetase	K01915	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117	521.0
TH2_k127_7148911_8	Radical SAM domain protein	K04070	-	1.97.1.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494	438.0
TH2_k127_7148911_9	peptidase M42 family protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494	426.0
TH2_k127_7184024_0	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	0.00000000000000000000000000000000000000000000412	175.0
TH2_k127_7184024_1	PFAM regulator of chromosome condensation, RCC1	-	-	-	0.00000000000000000000000000000000000000000003785	171.0
TH2_k127_7255914_0	Methyltransferase domain	-	-	-	0.0000000000000000000000000000000000000000000005616	173.0
TH2_k127_7255914_1	BAAT / Acyl-CoA thioester hydrolase C terminal	K06889	-	-	0.00000000000000000000000000000008859	138.0
TH2_k127_7264879_0	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	K02111	-	3.6.3.14	2.224e-265	828.0
TH2_k127_7264879_1	Elongator protein 3, MiaB family, Radical SAM	-	-	-	4.86e-261	821.0
TH2_k127_7264879_10	Psort location Cytoplasmic, score	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008779	291.0
TH2_k127_7264879_11	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	K01926	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000001565	273.0
TH2_k127_7264879_12	Protease prsW family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000003954	261.0
TH2_k127_7264879_13	overlaps another CDS with the same product name	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000004274	235.0
TH2_k127_7264879_14	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	K00820	-	2.6.1.16	0.00000000000000000000000000000000000000000000000000000002035	213.0
TH2_k127_7264879_15	Produces ATP from ADP in the presence of a proton gradient across the membrane	K02114	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	0.0000000000000000000000000000000000000000000000000000004252	196.0
TH2_k127_7264879_16	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	0.000000000000000000000000000000000000000000000112	175.0
TH2_k127_7264879_17	COG2963, Transposase and inactivated derivatives	K07483	-	-	0.0000000000000000000000000001181	117.0
TH2_k127_7264879_18	pyrroloquinoline quinone binding	K00117,K21430	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	1.1.5.2	0.000000000000000002117	92.0
TH2_k127_7264879_19	Rubrerythrin	-	-	-	0.000000006648	65.0
TH2_k127_7264879_2	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	K02112	-	3.6.3.14	1.021e-255	793.0
TH2_k127_7264879_20	Protein of unknown function (DUF1706)	-	-	-	0.00000001973	62.0
TH2_k127_7264879_21	COG3103 SH3 domain protein	K01448	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	0.00000112	60.0
TH2_k127_7264879_22	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	K21137	-	-	0.0007589	51.0
TH2_k127_7264879_3	Belongs to the D-alanine--D-alanine ligase family	K01921	-	6.3.2.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502	460.0
TH2_k127_7264879_4	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	K02484,K07642	-	2.7.13.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103	367.0
TH2_k127_7264879_5	Cell division protein FtsA	K03569	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647	349.0
TH2_k127_7264879_6	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	K02115	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392	335.0
TH2_k127_7264879_7	Amidohydrolase family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326	332.0
TH2_k127_7264879_8	Psort location Cytoplasmic, score 7.50	K01250	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013	311.0
TH2_k127_7264879_9	Two component transcriptional regulator, winged helix family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435	300.0
TH2_k127_7299714_0	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	K00937	-	2.7.4.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339	565.0
TH2_k127_7299714_1	PFAM ATP-binding region, ATPase domain protein	K07636	-	2.7.13.3	0.00000000000000000000000000000000000000000000000193	176.0
TH2_k127_73179_0	PFAM extracellular solute-binding protein, family 5	K02035	-	-	1.176e-270	849.0
TH2_k127_73179_1	PFAM binding-protein-dependent transport systems inner membrane component	K02034	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106	544.0
TH2_k127_73179_2	PFAM binding-protein-dependent transport systems inner membrane component	K02033	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668	500.0
TH2_k127_73179_3	PFAM aldo keto reductase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941	488.0
TH2_k127_73179_4	Belongs to the ABC transporter superfamily	K02031	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895	408.0
TH2_k127_73179_5	ROK family	-	-	-	0.000000000000000000000094	104.0
TH2_k127_73179_6	Oligopeptide/dipeptide transporter, C-terminal region	K02032	-	-	0.00000000000000000001391	94.0
TH2_k127_7330156_0	arylsulfatase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000008281	268.0
TH2_k127_7330156_1	oxidoreductase activity	K00059	-	1.1.1.100	0.00000000000000000000000000000000000000000000000000000000000000002274	232.0
TH2_k127_7330156_2	alpha/beta hydrolase fold	K01066	-	-	0.0000000000000000000000000000000000000000000000000000000008098	204.0
TH2_k127_7348372_0	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	K21071	-	2.7.1.11,2.7.1.90	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908	524.0
TH2_k127_7348372_1	Flavin containing amine oxidoreductase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711	336.0
TH2_k127_7348372_2	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	0.0000000000000000000000000000000000000000002474	170.0
TH2_k127_7357193_0	Aldehyde ferredoxin oxidoreductase, N-terminal domain	K03738	-	1.2.7.5	1.004e-218	694.0
TH2_k127_7357193_1	PFAM AAA ATPase central domain protein	K07478	-	-	1.197e-207	656.0
TH2_k127_7357193_10	stress-induced mitochondrial fusion	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429	357.0
TH2_k127_7357193_11	Carbon-nitrogen hydrolase	K03820	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787	330.0
TH2_k127_7357193_12	4Fe-4S binding domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327	309.0
TH2_k127_7357193_13	3'-5' exonuclease	K03684	-	3.1.13.5	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917	304.0
TH2_k127_7357193_14	Acyltransferase family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001664	297.0
TH2_k127_7357193_15	Acyltransferase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007613	290.0
TH2_k127_7357193_16	helix_turn_helix, Lux Regulon	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000005484	275.0
TH2_k127_7357193_17	Acyltransferase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000001218	283.0
TH2_k127_7357193_18	Acyltransferase family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000001043	278.0
TH2_k127_7357193_19	Sigma-70, region 4 type 2	K11618	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000003613	255.0
TH2_k127_7357193_2	Beta-Casp domain	K07576	-	-	2.29e-200	633.0
TH2_k127_7357193_20	Acyltransferase family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000001967	253.0
TH2_k127_7357193_21	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000005301	234.0
TH2_k127_7357193_22	Acyltransferase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000001222	222.0
TH2_k127_7357193_23	EamA-like transporter family	-	-	-	0.000000000000000000000000000000000000000000000000000000001271	211.0
TH2_k127_7357193_24	Histidine kinase	-	-	-	0.000000000000000000000000000000000000000000000000000004647	205.0
TH2_k127_7357193_25	alpha-ribazole phosphatase activity	K02226,K15634,K22305	-	3.1.3.3,3.1.3.73,5.4.2.12	0.00000000000000000000000000000000000000000000000001269	188.0
TH2_k127_7357193_26	-	K07403	-	-	0.000000000000000000000000000000000000000000000003865	179.0
TH2_k127_7357193_27	PFAM band 7 protein	-	-	-	0.000000000000000000000000000000000000000001181	165.0
TH2_k127_7357193_28	2 iron, 2 sulfur cluster binding	K02823,K05368	-	1.16.1.3,1.5.1.41	0.0000000000000000000000000000000000000000163	161.0
TH2_k127_7357193_29	phosphatase	K04459,K14165	-	3.1.3.16,3.1.3.48	0.0000000000000000000000000000000000004912	144.0
TH2_k127_7357193_3	helix_turn_helix, Lux Regulon	K03556	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708	603.0
TH2_k127_7357193_30	Histidine kinase	-	-	-	0.0000000000000000000000000000000000005741	154.0
TH2_k127_7357193_31	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	K07025	-	-	0.000000000000000000000000000000000002874	147.0
TH2_k127_7357193_32	Involved in the tonB-independent uptake of proteins	-	-	-	0.00000000000000000000000000000000003469	146.0
TH2_k127_7357193_33	hydroperoxide reductase activity	-	-	-	0.000000000000000000000000000001501	123.0
TH2_k127_7357193_34	acetyltransferase	K03789	-	2.3.1.128	0.000000000000000000000000000005435	124.0
TH2_k127_7357193_35	hydroperoxide reductase activity	-	-	-	0.000000000000000000000001322	105.0
TH2_k127_7357193_36	PFAM HlyD family secretion protein	K02022	-	-	0.00000000000000000000008488	103.0
TH2_k127_7357193_37	Putative auto-transporter adhesin, head GIN domain	-	-	-	0.00000000000000000004658	100.0
TH2_k127_7357193_38	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	0.0000000000001148	81.0
TH2_k127_7357193_39	PFAM Peptidase family M28	-	-	-	0.00000000008244	76.0
TH2_k127_7357193_4	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	K01791	-	5.1.3.14	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847	492.0
TH2_k127_7357193_40	Putative zinc- or iron-chelating domain	-	-	-	0.000000005747	65.0
TH2_k127_7357193_41	PFAM ThiamineS	-	-	-	0.0000008974	54.0
TH2_k127_7357193_5	PFAM band 7 protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647	451.0
TH2_k127_7357193_6	Synthesizes selenophosphate from selenide and ATP	K01008	-	2.7.9.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147	441.0
TH2_k127_7357193_7	PFAM CBS domain	K03699	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343	428.0
TH2_k127_7357193_8	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	K02472	-	1.1.1.336	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338	429.0
TH2_k127_7357193_9	PFAM major facilitator superfamily MFS_1	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045	418.0
TH2_k127_7374563_0	hydrolase activity, acting on ester bonds	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000005051	237.0
TH2_k127_7374563_1	Methyltransferase domain	-	-	-	0.000000000000000000000000000000000000000000000004601	181.0
TH2_k127_7374563_2	COG1073 Hydrolases of the alpha beta superfamily	K06889	-	-	0.0000000000000000000000001812	120.0
TH2_k127_7401990_0	Belongs to the GPI family	K01810,K13810	-	2.2.1.2,5.3.1.9	8.643e-305	959.0
TH2_k127_7401990_1	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	K00615	-	2.2.1.1	6.341e-294	915.0
TH2_k127_7401990_10	PFAM Citrate transporter	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273	374.0
TH2_k127_7401990_11	COG2211 Na melibiose symporter and related	K03292	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501	344.0
TH2_k127_7401990_12	Belongs to the MenA family. Type 1 subfamily	K02548	-	2.5.1.74	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028	328.0
TH2_k127_7401990_13	Binding-protein-dependent transport system inner membrane component	K02050	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902	325.0
TH2_k127_7401990_14	Belongs to the GHMP kinase family. GalK subfamily	K00849	-	2.7.1.6	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664	327.0
TH2_k127_7401990_15	thiamine-containing compound biosynthetic process	K02051	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164	315.0
TH2_k127_7401990_16	Protein of unknown function DUF58	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127	320.0
TH2_k127_7401990_17	PFAM sugar transferase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161	306.0
TH2_k127_7401990_18	ATPases associated with a variety of cellular activities	K02049	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715	305.0
TH2_k127_7401990_19	ABC transporter substrate-binding protein	K02035	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002176	307.0
TH2_k127_7401990_2	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265	581.0
TH2_k127_7401990_20	ABC-type dipeptide oligopeptide nickel transport systems, permease components	K02033	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000236	292.0
TH2_k127_7401990_21	PFAM binding-protein-dependent transport systems inner membrane component	K02034	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000515	273.0
TH2_k127_7401990_22	PFAM Trimethylamine methyltransferase (MTTB)	K14083	-	2.1.1.250	0.0000000000000000000000000000000000000000000000000000000000000000000000000004695	274.0
TH2_k127_7401990_23	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	K03183	-	2.1.1.163,2.1.1.201	0.000000000000000000000000000000000000000000000000000000000000000000000002232	254.0
TH2_k127_7401990_24	PFAM O-antigen polymerase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000004956	259.0
TH2_k127_7401990_25	lipopolysaccharide biosynthesis protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000006069	254.0
TH2_k127_7401990_26	Glycosyl transferase group 1	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000102	239.0
TH2_k127_7401990_27	Metallo-beta-lactamase superfamily	-	-	-	0.000000000000000000000000000000000000000000000000000000000001078	216.0
TH2_k127_7401990_28	transferase activity, transferring glycosyl groups	K16148	-	2.4.1.342	0.0000000000000000000000000000000000000000000000000000000001988	217.0
TH2_k127_7401990_29	Ribose/Galactose Isomerase	K01808	-	5.3.1.6	0.000000000000000000000000000000000000000000000000001913	187.0
TH2_k127_7401990_3	Melibiase	K07407	-	3.2.1.22	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855	504.0
TH2_k127_7401990_30	Belongs to the 5'-nucleotidase family	-	-	-	0.00000000000000000000000000000000000000000000000001075	198.0
TH2_k127_7401990_31	-	-	-	-	0.000000000000000000000000000000000000000000000000258	183.0
TH2_k127_7401990_32	Phospholipid methyltransferase	-	-	-	0.0000000000000000000000000000000000000000000000005635	182.0
TH2_k127_7401990_33	PFAM Glycosyl transferase, group 1	-	-	-	0.000000000000000000000000000000000000000000000002307	188.0
TH2_k127_7401990_35	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	0.000000000000000000000000000000000000000000000399	172.0
TH2_k127_7401990_36	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	K13292	-	-	0.00000000000000000000000000000000000000003982	161.0
TH2_k127_7401990_38	pterin-4-alpha-carbinolamine dehydratase	K01724	GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.2.1.96	0.0000000000000000000000000000000003743	136.0
TH2_k127_7401990_39	-	-	-	-	0.00000000000000000000000000001335	128.0
TH2_k127_7401990_4	FAD dependent oxidoreductase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252	499.0
TH2_k127_7401990_40	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	K01870	-	6.1.1.5	0.0000000000000000000000000002188	115.0
TH2_k127_7401990_41	Hypothetical methyltransferase	-	-	-	0.0000000000000000000003049	105.0
TH2_k127_7401990_42	Glutathione S-transferase, N-terminal domain	-	-	-	0.000000000000000000006194	94.0
TH2_k127_7401990_43	Metallo-beta-lactamase superfamily	-	-	-	0.000000000000000000008964	94.0
TH2_k127_7401990_44	-	-	-	-	0.00000000000000000001205	103.0
TH2_k127_7401990_45	Acetyltransferase (GNAT) domain	-	-	-	0.0000000000000000002097	100.0
TH2_k127_7401990_46	Enoyl-(Acyl carrier protein) reductase	-	-	-	0.000000000000000001727	94.0
TH2_k127_7401990_47	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	0.00000000001699	72.0
TH2_k127_7401990_5	PFAM Phosphotransferase enzyme family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063	467.0
TH2_k127_7401990_50	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	K03116	-	-	0.0001545	47.0
TH2_k127_7401990_6	ATPase associated with various cellular activities, AAA_3	K03924	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425	449.0
TH2_k127_7401990_7	Cys/Met metabolism PLP-dependent enzyme	K01761	-	4.4.1.11	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484	404.0
TH2_k127_7401990_8	Bacterial cellulose synthase subunit	K20541	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258	393.0
TH2_k127_7401990_9	PFAM polysaccharide biosynthesis protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622	374.0
TH2_k127_752628_0	Belongs to the glycosyl hydrolase 3 family	K05349	-	3.2.1.21	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757	531.0
TH2_k127_752628_1	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides	K03478	-	3.5.1.105	0.00000000000000000000000000000000000000001461	163.0
TH2_k127_7582474_0	FAD linked oxidase domain protein	K00103,K16653	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.3.8,1.1.98.3	0.00000000000000000000000000000000000000000000000000000000000935	213.0
TH2_k127_7582474_1	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	0.0000000000000000000000000000000000000000000000000000000003101	211.0
TH2_k127_7582474_2	PAS PAC and GAF sensor-containing diguanylate cyclase	-	-	-	0.0002068	51.0
TH2_k127_7585445_0	Flavin containing amine oxidoreductase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221	555.0
TH2_k127_7585445_1	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	0.000006302	56.0
TH2_k127_7740942_0	Iron permease FTR1 family	K07243	-	-	0.0000000000000000000000000000000000000000000000000000000000000000003887	238.0
TH2_k127_7740942_1	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	K03801	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	0.00000000000000266	79.0
TH2_k127_7741828_0	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	K12528	-	-	0.0	1495.0
TH2_k127_7741828_1	Belongs to the 5'-nucleotidase family	K01081	-	3.1.3.5	0.0	1399.0
TH2_k127_7741828_10	TIGRFAM FeS assembly protein SufD	K09015	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019	584.0
TH2_k127_7741828_101	Rieske [2Fe-2S] domain	K02636,K03886	-	1.10.9.1	0.0000000000000002012	87.0
TH2_k127_7741828_102	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	0.0000000000000006226	83.0
TH2_k127_7741828_103	Domain of unknown function (DUF4404)	-	-	-	0.0000000000005482	72.0
TH2_k127_7741828_104	Cytochrome b5-like Heme Steroid binding domain	-	-	-	0.000000000002803	71.0
TH2_k127_7741828_105	protein secretion	K03116,K03117	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	0.0000000001359	66.0
TH2_k127_7741828_107	Belongs to the sulfur carrier protein TusA family	-	-	-	0.000000004317	61.0
TH2_k127_7741828_109	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	0.0000001051	57.0
TH2_k127_7741828_11	Sulphur transport	K07112	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358	570.0
TH2_k127_7741828_110	-	-	-	-	0.0000001383	62.0
TH2_k127_7741828_112	-	-	-	-	0.000003371	57.0
TH2_k127_7741828_12	Spermine/spermidine synthase domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339	559.0
TH2_k127_7741828_14	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191	543.0
TH2_k127_7741828_15	LysM domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029	544.0
TH2_k127_7741828_16	TIGRFAM FeS assembly protein SufB	K09014	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375	562.0
TH2_k127_7741828_17	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	K01042	-	2.9.1.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064	515.0
TH2_k127_7741828_18	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	K17758,K17759	-	4.2.1.136,5.1.99.6	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954	516.0
TH2_k127_7741828_19	ABC1 family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549	515.0
TH2_k127_7741828_2	Cytochrome b/b6/petB	-	-	-	0.0	1154.0
TH2_k127_7741828_20	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	K02835	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052	504.0
TH2_k127_7741828_21	LysM domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924	513.0
TH2_k127_7741828_22	SPFH domain-Band 7 family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497	490.0
TH2_k127_7741828_23	PFAM tRNA synthetase class II (G H P and S)	K01892	-	6.1.1.21	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000543	482.0
TH2_k127_7741828_24	Bacterial sugar transferase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626	479.0
TH2_k127_7741828_25	PFAM ABC transporter related	K09013	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619	458.0
TH2_k127_7741828_26	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	K01409	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	2.3.1.234	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709	456.0
TH2_k127_7741828_27	LysM domain	K03046,K03641,K08642	-	2.7.7.6	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009441	464.0
TH2_k127_7741828_28	Pyridoxal-phosphate dependent enzyme	K17950	-	4.4.1.25	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272	450.0
TH2_k127_7741828_29	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	K00566	-	2.8.1.13	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009618	437.0
TH2_k127_7741828_3	Peptidase M16C associated	K06972	-	-	0.0	1097.0
TH2_k127_7741828_30	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	K04487	-	2.8.1.7	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057	437.0
TH2_k127_7741828_31	PFAM Methicillin resistance protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172	433.0
TH2_k127_7741828_32	AAA domain, putative AbiEii toxin, Type IV TA system	K01990	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187	413.0
TH2_k127_7741828_33	VIT family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381	413.0
TH2_k127_7741828_34	acid phosphatase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364	401.0
TH2_k127_7741828_35	transferase activity, transferring glycosyl groups	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278	392.0
TH2_k127_7741828_36	Belongs to the arginase family	K01480,K18459	-	3.5.3.11,3.5.3.17	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326	387.0
TH2_k127_7741828_37	PFAM Methicillin resistance protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164	374.0
TH2_k127_7741828_38	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	K02484,K07642	-	2.7.13.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051	377.0
TH2_k127_7741828_39	XdhC Rossmann domain	K07402	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244	357.0
TH2_k127_7741828_4	penicillin amidase	K01434	-	3.5.1.11	3.376e-290	916.0
TH2_k127_7741828_40	Metallopeptidase family M24	K01262	-	3.4.11.9	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473	344.0
TH2_k127_7741828_41	-	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156	347.0
TH2_k127_7741828_42	Belongs to the FPP GGPP synthase family	K13787	-	2.5.1.1,2.5.1.10,2.5.1.29	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998	331.0
TH2_k127_7741828_43	inorganic diphosphatase activity	K15986	-	3.6.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146	327.0
TH2_k127_7741828_44	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118	323.0
TH2_k127_7741828_45	N-acetylglucosaminylinositol deacetylase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997	308.0
TH2_k127_7741828_46	Sulphur transport	K07112	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205	299.0
TH2_k127_7741828_47	Integral membrane protein TerC family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363	301.0
TH2_k127_7741828_48	Two component transcriptional regulator, winged helix family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871	297.0
TH2_k127_7741828_49	Transcriptional regulatory protein, C terminal	K07658	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678	295.0
TH2_k127_7741828_5	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	K03703	-	-	2.73e-281	875.0
TH2_k127_7741828_51	PFAM Methyltransferase type 11	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001708	294.0
TH2_k127_7741828_52	PFAM Alcohol dehydrogenase, zinc-binding	K00001	-	1.1.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005478	295.0
TH2_k127_7741828_53	PFAM DNA methylase N-4 N-6 domain protein	K00571	-	2.1.1.72	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001083	311.0
TH2_k127_7741828_54	Enoyl-(Acyl carrier protein) reductase	K00059	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000639	282.0
TH2_k127_7741828_55	PFAM regulatory protein, ArsR	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003556	278.0
TH2_k127_7741828_56	acid phosphatase activity	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000005583	289.0
TH2_k127_7741828_57	short-chain dehydrogenase reductase SDR	K01784	-	5.1.3.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000001405	280.0
TH2_k127_7741828_58	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	K02379	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000002071	271.0
TH2_k127_7741828_59	PFAM SNARE associated Golgi protein	K03975	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000002854	267.0
TH2_k127_7741828_6	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	3.032e-241	752.0
TH2_k127_7741828_60	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000224	266.0
TH2_k127_7741828_61	ABC-2 family transporter protein	K01992	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000002419	266.0
TH2_k127_7741828_62	domain, Protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000002708	280.0
TH2_k127_7741828_63	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	K02493	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	0.000000000000000000000000000000000000000000000000000000000000000000000001236	256.0
TH2_k127_7741828_64	Mut7-C RNAse domain	K09122	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000002098	251.0
TH2_k127_7741828_65	Cupin domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000004011	243.0
TH2_k127_7741828_66	ABC-2 family transporter protein	K01992	-	-	0.00000000000000000000000000000000000000000000000000000000000000007305	233.0
TH2_k127_7741828_67	Thioesterase superfamily protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000006347	222.0
TH2_k127_7741828_68	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	K03118	-	-	0.0000000000000000000000000000000000000000000000000000000002121	216.0
TH2_k127_7741828_69	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	K03625	-	-	0.000000000000000000000000000000000000000000000000000000002375	202.0
TH2_k127_7741828_7	Short-chain dehydrogenase reductase SDR	-	-	-	2.654e-237	749.0
TH2_k127_7741828_70	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	K01802	-	5.2.1.8	0.000000000000000000000000000000000000000000000000000000002734	209.0
TH2_k127_7741828_71	Serine threonine protein kinase	-	-	-	0.00000000000000000000000000000000000000000000000000000001849	221.0
TH2_k127_7741828_72	SUF system FeS assembly protein, NifU family	K04488	-	-	0.0000000000000000000000000000000000000000000000000000006253	194.0
TH2_k127_7741828_73	Haloacid dehalogenase-like hydrolase	K01560	-	3.8.1.2	0.000000000000000000000000000000000000000000000000000001913	197.0
TH2_k127_7741828_74	FAD binding domain in molybdopterin dehydrogenase	K03519,K12529	-	1.2.5.3	0.0000000000000000000000000000000000000000000000000002407	194.0
TH2_k127_7741828_75	Protein of unknown function (DUF1461)	-	-	-	0.0000000000000000000000000000000000000000000000000009159	191.0
TH2_k127_7741828_76	Cytochrome b(N-terminal)/b6/petB	-	-	-	0.00000000000000000000000000000000000000000000000007567	199.0
TH2_k127_7741828_77	Telomere recombination	K07566	-	2.7.7.87	0.00000000000000000000000000000000000000000000000853	179.0
TH2_k127_7741828_78	PFAM OsmC family protein	K07397	-	-	0.0000000000000000000000000000000000000000000004038	171.0
TH2_k127_7741828_79	family 25	K01185,K07273	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17	0.0000000000000000000000000000000000000000004205	167.0
TH2_k127_7741828_8	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	K01689	-	4.2.1.11	7.519e-233	725.0
TH2_k127_7741828_80	TIGRFAM competence damage-inducible protein CinA	K03742,K03743	-	3.5.1.42	0.000000000000000000000000000000000000000005148	160.0
TH2_k127_7741828_81	Endoribonuclease L-PSP	K09022	-	3.5.99.10	0.0000000000000000000000000000000000000003007	156.0
TH2_k127_7741828_82	PFAM Rieske 2Fe-2S domain protein	K00363,K05710	-	1.7.1.15	0.00000000000000000000000000000000000000372	149.0
TH2_k127_7741828_83	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	0.0000000000000000000000000000000000938	138.0
TH2_k127_7741828_84	Asp23 family, cell envelope-related function	-	-	-	0.0000000000000000000000000000000003709	134.0
TH2_k127_7741828_85	Pfam:DUF59	-	-	-	0.000000000000000000000000000000001466	134.0
TH2_k127_7741828_87	YHYH protein	-	-	-	0.000000000000000000000000000000004706	147.0
TH2_k127_7741828_88	PFAM Nitroreductase	-	-	-	0.000000000000000000000000000000005962	134.0
TH2_k127_7741828_89	TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases	K00655	-	2.3.1.51	0.000000000000000000000000000000007278	136.0
TH2_k127_7741828_9	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	K11717	-	2.8.1.7,4.4.1.16	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035	610.0
TH2_k127_7741828_91	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	0.0000000000000000000000000000002557	130.0
TH2_k127_7741828_92	Acetyltransferase (GNAT) domain	-	-	-	0.000000000000000000000000000001382	126.0
TH2_k127_7741828_93	Protein of unknown function (DUF402)	-	-	-	0.00000000000000000000000000006315	124.0
TH2_k127_7741828_94	cyclic nucleotide binding	K10914	-	-	0.000000000000000000000000001104	117.0
TH2_k127_7741828_95	helix_turn_helix, Arsenical Resistance Operon Repressor	K03892	-	-	0.000000000000000000000000001568	115.0
TH2_k127_7741828_96	-	-	-	-	0.000000000000000000000008655	109.0
TH2_k127_7741828_97	Ig-like domain from next to BRCA1 gene	-	-	-	0.00000000000000000001341	101.0
TH2_k127_7741828_98	-	-	-	-	0.00000000000000000001532	98.0
TH2_k127_7741828_99	Cytochrome c554 and c-prime	-	-	-	0.0000000000000000245	96.0
TH2_k127_7774955_0	PFAM regulator of chromosome condensation, RCC1	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000007361	257.0
TH2_k127_7774955_1	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	0.0000000000000000000000000000000000000000003179	170.0
TH2_k127_7774955_2	Psort location Cytoplasmic, score	-	-	-	0.00000000000000000000000009263	108.0
TH2_k127_7774955_3	transposase activity	-	-	-	0.00000000000000000004554	92.0
TH2_k127_7774955_6	WD40 domain protein beta propeller	-	-	-	0.00007248	55.0
TH2_k127_7798511_0	purine nucleotide biosynthetic process	K01812,K02529,K16210	-	5.3.1.12	0.0000000000000000000000000000000000005835	142.0
TH2_k127_7798511_1	Transposase	-	-	-	0.000000000000000000000007601	104.0
TH2_k127_7798511_2	PFAM PfkB domain protein	K00874	-	2.7.1.45	0.00000000000000000002106	94.0
TH2_k127_7851849_0	beta-lactamase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373	308.0
TH2_k127_7851849_1	Methyltransferase domain	-	-	-	0.000000000000000000000000000000000002215	142.0
TH2_k127_7851849_2	BAAT / Acyl-CoA thioester hydrolase C terminal	K06889	-	-	0.00000000000000000000000000001827	132.0
TH2_k127_785826_0	Aminotransferase class-III	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341	614.0
TH2_k127_785826_1	Aldehyde ferredoxin oxidoreductase, N-terminal domain	K03738	-	1.2.7.5	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821	569.0
TH2_k127_785826_10	-	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000003777	269.0
TH2_k127_785826_11	amino acid	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000008571	254.0
TH2_k127_785826_12	sequence-specific DNA binding	K03718,K03719	-	-	0.0000000000000000000000000000000000000000001001	164.0
TH2_k127_785826_2	Saccharopine dehydrogenase	K00290	-	1.5.1.7	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829	533.0
TH2_k127_785826_3	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	K00821,K05830,K09251	-	2.6.1.11,2.6.1.17,2.6.1.82	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493	526.0
TH2_k127_785826_4	PFAM Aldehyde ferredoxin oxidoreductase	K03738	-	1.2.7.5	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497	527.0
TH2_k127_785826_5	PFAM extracellular solute-binding protein family 1	K11069	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608	515.0
TH2_k127_785826_6	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	K00823	-	2.6.1.19	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086	484.0
TH2_k127_785826_7	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	K11072	-	3.6.3.31	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111	404.0
TH2_k127_785826_8	PFAM binding-protein-dependent transport systems inner membrane component	K11071	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274	391.0
TH2_k127_785826_9	PFAM binding-protein-dependent transport systems inner membrane component	K11070	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214	369.0
TH2_k127_7874153_0	ABC transporter transmembrane region	K06147	-	-	2.339e-244	769.0
TH2_k127_7874153_1	ABC transporter transmembrane region	K06147	-	-	9.202e-242	761.0
TH2_k127_7874153_10	COG0477 Permeases of the major facilitator superfamily	K08153	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228	319.0
TH2_k127_7874153_11	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614	316.0
TH2_k127_7874153_12	PFAM binding-protein-dependent transport systems inner membrane component	K02033	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000006029	282.0
TH2_k127_7874153_13	Trypsin-like peptidase domain	K04771	-	3.4.21.107	0.000000000000000000000000000000000000000000000000000000000000000000000000000009647	269.0
TH2_k127_7874153_14	SpoU rRNA Methylase family	K03218,K03437,K21514	-	2.1.1.185,2.1.1.208	0.00000000000000000000000000000000000000000000000000000000000000000000000009062	256.0
TH2_k127_7874153_15	Phage integrase, N-terminal SAM-like domain	K03733	-	-	0.0000000000000000000000000000000000000000000000000000000000000004079	230.0
TH2_k127_7874153_16	PFAM transglutaminase domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000003579	244.0
TH2_k127_7874153_17	cytidyltransferase-related domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000007115	214.0
TH2_k127_7874153_18	Protein of unknown function DUF58	-	-	-	0.0000000000000000000000000000000000000000000000003169	192.0
TH2_k127_7874153_19	Acetyltransferase (GNAT) domain	-	-	-	0.0000000000000000000000000000000000000006776	158.0
TH2_k127_7874153_2	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	K01950	-	6.3.5.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353	475.0
TH2_k127_7874153_20	-	-	-	-	0.00000000000000000000000000000000000008396	147.0
TH2_k127_7874153_21	transposase activity	K07483,K07497	-	-	0.000000000000000000000000000000001324	134.0
TH2_k127_7874153_22	helix_turn_helix, Lux Regulon	-	-	-	0.000000000000000000000000000003298	126.0
TH2_k127_7874153_23	-	-	-	-	0.0000000000000000000000000007168	119.0
TH2_k127_7874153_24	Bulb-type mannose-specific lectin	-	-	-	0.000000000000000000000000001918	127.0
TH2_k127_7874153_25	Amino-transferase class IV	K00826	-	2.6.1.42	0.000000000000000000000003687	113.0
TH2_k127_7874153_26	trisaccharide binding	K11912	-	2.7.11.1	0.000000000000001023	91.0
TH2_k127_7874153_27	cellulase activity	-	-	-	0.000000000000001673	91.0
TH2_k127_7874153_28	DNA polymerase	-	-	-	0.0000000007188	60.0
TH2_k127_7874153_29	Belongs to the 'phage' integrase family	-	-	-	0.000002317	53.0
TH2_k127_7874153_3	Binding-protein-dependent transport system inner membrane component	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412	464.0
TH2_k127_7874153_30	-	-	-	-	0.0003338	46.0
TH2_k127_7874153_4	SMART Elongator protein 3 MiaB NifB	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742	441.0
TH2_k127_7874153_5	-	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442	411.0
TH2_k127_7874153_6	drug transmembrane transporter activity	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908	417.0
TH2_k127_7874153_7	Integrase core domain	K07497	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209	403.0
TH2_k127_7874153_9	TIGRFAM oligopeptide dipeptide ABC transporter	K02031,K02032	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373	334.0
TH2_k127_7928655_0	Glycosyltransferase 36 associated	-	-	-	0.0	1343.0
TH2_k127_7928655_1	Putative carbohydrate binding domain	K00702	-	2.4.1.20	0.0	1228.0
TH2_k127_7928655_10	glycerophosphodiester transmembrane transport	K02026	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778	403.0
TH2_k127_7928655_11	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	K03074	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353	399.0
TH2_k127_7928655_12	transmembrane transport	K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796	377.0
TH2_k127_7928655_13	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	K03072	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575	351.0
TH2_k127_7928655_14	TIGRFAM Competence protein ComEA, helix-hairpin-helix	K17717	-	3.1.4.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104	347.0
TH2_k127_7928655_15	PFAM TrkA-N domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508	309.0
TH2_k127_7928655_16	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145	310.0
TH2_k127_7928655_17	helix_turn _helix lactose operon repressor	K02529	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291	301.0
TH2_k127_7928655_18	Belongs to the glycosyl hydrolase 5 (cellulase A) family	K01190	-	3.2.1.23	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001402	292.0
TH2_k127_7928655_19	integral membrane protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001827	291.0
TH2_k127_7928655_2	Glycosyl hydrolase 36 superfamily, catalytic domain	K00702,K13688,K21298	-	2.4.1.20,2.4.1.333	0.0	1066.0
TH2_k127_7928655_20	PFAM Stage II sporulation E family protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003493	282.0
TH2_k127_7928655_21	malonyl CoA-acyl carrier protein transacylase	K00645	-	2.3.1.39	0.0000000000000000000000000000000000000000000000000000000000000000000000000000002656	275.0
TH2_k127_7928655_22	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000009712	261.0
TH2_k127_7928655_23	methyltransferase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000001713	246.0
TH2_k127_7928655_24	Belongs to the glycosyl hydrolase 18 family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000005391	241.0
TH2_k127_7928655_25	Maltose acetyltransferase	K00661	-	2.3.1.79	0.000000000000000000000000000000000000000000000000000003441	196.0
TH2_k127_7928655_26	Cupin 2, conserved barrel domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000007127	191.0
TH2_k127_7928655_27	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	0.000000000000000000000000000000000000000000000000002541	193.0
TH2_k127_7928655_28	Tyrosine phosphatase family	-	-	-	0.0000000000000000000000000000000000000000000002909	175.0
TH2_k127_7928655_29	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides	K03478	-	3.5.1.105	0.000000000000000000000000000000000000000000006196	173.0
TH2_k127_7928655_3	Belongs to the glycosyl hydrolase 3 family	K05349	-	3.2.1.21	1.384e-287	908.0
TH2_k127_7928655_30	NUDIX domain	K08310	-	3.6.1.67	0.00000000000000000000000000000000000000000002378	165.0
TH2_k127_7928655_31	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	0.00000000000000000000000000000004442	128.0
TH2_k127_7928655_32	Belongs to the bacterial ribosomal protein bL32 family	K02911	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	0.0000000000000000004149	89.0
TH2_k127_7928655_33	Methyltransferase domain	-	-	-	0.0000000000000000006507	97.0
TH2_k127_7928655_34	HD domain	-	-	-	0.000000000000000000791	89.0
TH2_k127_7928655_35	-	-	-	-	0.000000000001611	76.0
TH2_k127_7928655_36	Ketosteroid isomerase-related protein	-	-	-	0.000000000001762	73.0
TH2_k127_7928655_37	PFAM FecR protein	-	-	-	0.0000000007493	62.0
TH2_k127_7928655_4	phosphoenolpyruvate carboxykinase (ATP) activity	K01610	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	1.65e-228	719.0
TH2_k127_7928655_40	HD domain	-	-	-	0.00001145	50.0
TH2_k127_7928655_41	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	K00648	-	2.3.1.180	0.0001468	54.0
TH2_k127_7928655_5	PFAM glycoside hydrolase, family 1	K05350	-	3.2.1.21	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589	595.0
TH2_k127_7928655_6	PFAM glycosidase PH1107-related	K18785,K20885	-	2.4.1.319,2.4.1.320,2.4.1.339,2.4.1.340	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086	554.0
TH2_k127_7928655_7	Family 4 glycosyl hydrolase	K01222	-	3.2.1.86	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716	536.0
TH2_k127_7928655_8	carbohydrate transport	K02027	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379	505.0
TH2_k127_7928655_9	Aminotransferase	K00812	-	2.6.1.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993	471.0
TH2_k127_7951858_0	(ABC) transporter	K06147,K11085	-	-	3.926e-249	781.0
TH2_k127_7951858_1	Zinc-binding dehydrogenase	K22231	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286	607.0
TH2_k127_7951858_10	Oxidoreductase family, C-terminal alpha/beta domain	K00010	-	1.1.1.18,1.1.1.369	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957	364.0
TH2_k127_7951858_11	ATPases associated with a variety of cellular activities	K02010	-	3.6.3.30	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678	362.0
TH2_k127_7951858_12	Phosphate transporter family	K03306	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028	349.0
TH2_k127_7951858_13	PFAM Xylose isomerase domain protein TIM barrel	K06606	-	5.3.99.11	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806	333.0
TH2_k127_7951858_14	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351	332.0
TH2_k127_7951858_15	Protein of unknown function (DUF4256)	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658	317.0
TH2_k127_7951858_16	Aldo/keto reductase family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364	319.0
TH2_k127_7951858_17	Transmembrane secretion effector	K08225	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126	319.0
TH2_k127_7951858_18	TIM barrel	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000156	295.0
TH2_k127_7951858_19	helix_turn _helix lactose operon repressor	K05499	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000008138	282.0
TH2_k127_7951858_2	BPG-independent PGAM N-terminus (iPGM_N)	K15633	-	5.4.2.12	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025	614.0
TH2_k127_7951858_20	Haloacid dehalogenase-like hydrolase	K07025	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000007274	261.0
TH2_k127_7951858_21	HAD-hyrolase-like	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000001331	241.0
TH2_k127_7951858_22	alcohol dehydrogenase	K00008	-	1.1.1.14	0.00000000000000000000000000000000000000000000000000005835	203.0
TH2_k127_7951858_23	phosphate transport regulator (Distant homolog of PhoU)	K07220	-	-	0.0000000000000000000000000000000000000000000000003498	182.0
TH2_k127_7951858_24	Bacterial extracellular solute-binding protein	-	-	-	0.000000000000000000000000000000000000000000000005893	188.0
TH2_k127_7951858_25	HAD-hyrolase-like	K07025	-	-	0.00000000000000000000000000000000000000000000001036	190.0
TH2_k127_7951858_26	phosphatase activity	-	-	-	0.0000000000000000000000000000000000000000000007093	184.0
TH2_k127_7951858_27	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	K00852,K00856,K10710,K22026	-	2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73	0.0000000000000000000000000000000000000000000477	171.0
TH2_k127_7951858_28	Haloacid dehalogenase-like hydrolase	K07025	-	-	0.000000000000000000000000000000000000006933	164.0
TH2_k127_7951858_29	Xylose isomerase-like TIM barrel	-	-	-	0.0000000000000000000000000000000008719	148.0
TH2_k127_7951858_3	PfkB domain protein	K00874	-	2.7.1.45	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675	604.0
TH2_k127_7951858_30	transcriptional regulator, RpiR family	-	-	-	0.0000000000000000000000000000001798	135.0
TH2_k127_7951858_31	HAD-hyrolase-like	-	-	-	0.0000000000000000000000000002061	126.0
TH2_k127_7951858_32	acetoacetate decarboxylase activity	-	-	-	0.0000000000000001633	87.0
TH2_k127_7951858_34	Phosphoribulokinase / Uridine kinase family	K00876	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006464,GO:0006508,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007610,GO:0007631,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009611,GO:0009628,GO:0009987,GO:0016301,GO:0016310,GO:0016579,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0036211,GO:0042221,GO:0042455,GO:0043094,GO:0043097,GO:0043170,GO:0043174,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0048678,GO:0050896,GO:0051716,GO:0055086,GO:0070482,GO:0070646,GO:0070647,GO:0070887,GO:0071453,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	0.000000000002352	79.0
TH2_k127_7951858_35	Transposase (IS116 IS110 IS902 family)	-	-	-	0.00000000009155	68.0
TH2_k127_7951858_36	Cytidine monophosphokinase	K00876	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	0.0000000005232	72.0
TH2_k127_7951858_38	Beta-lactamase superfamily domain	-	-	-	0.000007508	57.0
TH2_k127_7951858_4	tagaturonate epimerase	K21619	-	5.1.2.7	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013	610.0
TH2_k127_7951858_5	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	K00033	-	1.1.1.343,1.1.1.44	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047	611.0
TH2_k127_7951858_6	Creatinine amidohydrolase	K01470,K22232	-	3.5.2.10	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501	528.0
TH2_k127_7951858_7	Binding-protein-dependent transport system inner membrane component	K02011	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688	519.0
TH2_k127_7951858_8	lactate racemase activity	K22373	-	5.1.2.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998	434.0
TH2_k127_7951858_9	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	K15635	-	5.4.2.12	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383	415.0
TH2_k127_8005510_0	denitrification pathway	K15876	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729	570.0
TH2_k127_8005510_1	formate dehydrogenase	-	-	-	0.0000000000000000000000006488	109.0
TH2_k127_8056339_0	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	K00772	-	2.4.2.28	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186	331.0
TH2_k127_8056339_1	PFAM Forkhead-associated protein	-	-	-	0.00000000000000000000000001119	114.0
TH2_k127_8056339_2	PFAM Forkhead-associated protein	-	-	-	0.00000000000000000000000001732	113.0
TH2_k127_8075240_0	Cysteine-rich secretory protein family	-	-	-	7.597e-199	644.0
TH2_k127_8075240_1	Glycosyl hydrolases family 2, sugar binding domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677	612.0
TH2_k127_8075240_10	ROK family	K00845	-	2.7.1.2	0.0000000000000000000000000000000000000000000000000000000000003131	225.0
TH2_k127_8075240_11	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	K00820	-	2.6.1.16	0.0000000000000000000000000000000000000000000000000000000002527	215.0
TH2_k127_8075240_12	peptidase activity	K01286	-	3.4.16.4	0.0000000000000000000000000000000000000000000000000004303	199.0
TH2_k127_8075240_13	Acetyltransferase (GNAT) domain	-	-	-	0.00000000000000000000000000000000000000000001859	167.0
TH2_k127_8075240_14	transcriptional	K03710	-	-	0.0000000000000000000000000000000000000000001461	169.0
TH2_k127_8075240_15	Diguanylate cyclase	-	-	-	0.00000000000000000001603	93.0
TH2_k127_8075240_16	PFAM FecR protein	-	-	-	0.000000002365	61.0
TH2_k127_8075240_17	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	0.0001277	49.0
TH2_k127_8075240_18	AAA-like domain	-	-	-	0.0005623	44.0
TH2_k127_8075240_2	Penicillin-Binding Protein C-terminus Family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323	611.0
TH2_k127_8075240_3	Bacterial extracellular solute-binding protein	K02027	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582	423.0
TH2_k127_8075240_4	Belongs to the 'phage' integrase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762	364.0
TH2_k127_8075240_5	Major facilitator Superfamily	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418	371.0
TH2_k127_8075240_6	Binding-protein-dependent transport system inner membrane component	K02025	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465	326.0
TH2_k127_8075240_7	PFAM aminoglycoside phosphotransferase	K02204	-	2.7.1.39	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095	325.0
TH2_k127_8075240_8	Polysaccharide biosynthesis protein	K01784	-	5.1.3.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252	314.0
TH2_k127_8075240_9	Binding-protein-dependent transport system inner membrane component	K02026	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000004158	269.0
TH2_k127_8087077_0	FAD binding domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625	332.0
TH2_k127_8087077_1	Response regulator, receiver	K02487,K03407,K03413,K06596,K11526,K13490	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	0.000000000000000000000000000000000000000000000000000004608	196.0
TH2_k127_8087077_2	SIR2-like domain	-	-	-	0.0000000000001755	78.0
TH2_k127_8092736_0	PFAM Type II secretion system protein E	K02283	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305	396.0
TH2_k127_8092736_1	Aldo/keto reductase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136	320.0
TH2_k127_8168274_0	Zinc-binding dehydrogenase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185	312.0
TH2_k127_8168274_1	acyl-CoA dehydrogenase	-	-	-	0.0000000000000000000000000000000000000000006321	159.0
TH2_k127_8168274_2	Carboxyl transferase domain	K01966	-	2.1.3.15,6.4.1.3	0.0000000000003223	70.0
TH2_k127_8341854_0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	K01866	-	6.1.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107	307.0
TH2_k127_8341854_1	NAD-dependent epimerase dehydratase	K07071	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000001399	267.0
TH2_k127_8341854_2	HNH endonuclease	-	-	-	0.0000000000000000000000000000000000000000000000000009433	186.0
TH2_k127_8356342_0	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	K00948	-	2.7.6.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774	444.0
TH2_k127_8356342_1	TIGRFAM LAO AO transport system ATPase	K07588	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508	327.0
TH2_k127_8356342_2	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	K10563	-	3.2.2.23,4.2.99.18	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357	307.0
TH2_k127_8356342_3	PFAM cobalamin B12-binding domain protein	K01849	-	5.4.99.2	0.00000000000000000000000000000000000000000000000000000000000007791	215.0
TH2_k127_8356342_4	-	-	-	-	0.0000000000000000000000000000000000000000000000000000003744	202.0
TH2_k127_8356342_6	-	-	-	-	0.0000007485	55.0
TH2_k127_843351_0	TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit	K00198	-	1.2.7.4	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086	462.0
TH2_k127_843351_1	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase	K00162,K21417	-	1.2.4.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992	314.0
TH2_k127_843351_2	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	K00161,K21416	-	1.2.4.1	0.00000000000000000000000000000000000000000000000000000000000000001579	236.0
TH2_k127_843351_3	4Fe-4S dicluster domain	K00196	-	-	0.000000000000000000000000000000000000000000000000000000000006138	214.0
TH2_k127_843351_4	-	-	-	-	0.0000000003129	67.0
TH2_k127_8456185_0	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	K11618	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006151	289.0
TH2_k127_8456185_1	Histidine kinase	-	-	-	0.000000000000000000000000000000000000000000000006465	179.0
TH2_k127_8467063_0	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	K00012	-	1.1.1.22	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623	546.0
TH2_k127_8467063_1	Methyltransferase domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105	366.0
TH2_k127_8467063_10	Thioredoxin	K05838	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	0.00000000000000844	76.0
TH2_k127_8467063_11	gas vesicle protein	-	-	-	0.0004643	48.0
TH2_k127_8467063_2	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	K00606	-	2.1.2.11	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852	354.0
TH2_k127_8467063_3	transferase activity, transferring glycosyl groups	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004501	298.0
TH2_k127_8467063_4	denitrification pathway	K15876	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000192	275.0
TH2_k127_8467063_5	Virulence factor BrkB	K07058	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000002845	251.0
TH2_k127_8467063_6	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	0.00000000000000000000000000000000000000000000000000759	194.0
TH2_k127_8467063_7	2-dehydropantoate 2-reductase activity	K00077	-	1.1.1.169	0.00000000000000000000000000000000000000000000000001462	192.0
TH2_k127_8467063_8	Response regulator, receiver	K11443	-	-	0.00000000000000000000000000000000004542	139.0
TH2_k127_8467063_9	-	-	-	-	0.0000000000000000000000317	110.0
TH2_k127_8503428_0	Belongs to the HAD-like hydrolase superfamily	K01101	-	3.1.3.41	0.0000000000000000000000000000000000000000000000000000000003321	214.0
TH2_k127_8503428_1	PFAM Alcohol dehydrogenase	K00008	-	1.1.1.14	0.000000000000000000000000000000000000000000000000000003984	196.0
TH2_k127_8503428_2	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	0.00000000000000000000000000000000000000000000006996	174.0
TH2_k127_8503428_3	Belongs to the ribulose-phosphate 3-epimerase family	K01783	-	5.1.3.1	0.0000000000000000000000000000000000000000000007463	173.0
TH2_k127_8503428_4	Orotidine 5'-phosphate decarboxylase / HUMPS family	K08093	-	4.1.2.43	0.00000000000000000000000000000000000001128	153.0
TH2_k127_8503428_5	Putative adhesin	-	-	-	0.0000004091	61.0
TH2_k127_8514146_0	PFAM major facilitator superfamily MFS_1	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297	445.0
TH2_k127_8514146_1	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	K02863	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128	344.0
TH2_k127_8514146_10	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	K02864	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.000000000000000000000000000000000000000000000000001997	187.0
TH2_k127_8514146_11	DegV family	-	-	-	0.000000000000000000000000000000000000000000000000005272	192.0
TH2_k127_8514146_12	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	K02935	-	-	0.000000000000000000000000000000000000000000000001061	176.0
TH2_k127_8514146_13	PFAM regulatory protein TetR	-	-	-	0.00000000000000000000000000000000000000000000009913	175.0
TH2_k127_8514146_14	Transcriptional regulator	-	-	-	0.0000000000000000000000000000000000000000001547	171.0
TH2_k127_8514146_15	-	-	-	-	0.000000000000000000000000000000000006671	139.0
TH2_k127_8514146_16	Belongs to the short-chain dehydrogenases reductases (SDR) family	K07124	-	-	0.0000000000000000000000000000000007924	141.0
TH2_k127_8514146_17	Protein of unknown function (DUF2089)	-	-	-	0.000000000000000000000000000000002343	132.0
TH2_k127_8514146_18	-	-	-	-	0.00000000000000000000000000001237	131.0
TH2_k127_8514146_19	Belongs to the bacterial ribosomal protein bL33 family	K02913	-	-	0.00000000000000000000003167	99.0
TH2_k127_8514146_2	NAD-dependent epimerase dehydratase	K00091	-	1.1.1.219	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721	346.0
TH2_k127_8514146_20	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	K02358	-	-	0.00000000000000001303	82.0
TH2_k127_8514146_22	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	K03073	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	0.0000001673	55.0
TH2_k127_8514146_3	Participates in transcription elongation, termination and antitermination	K02601	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018	324.0
TH2_k127_8514146_4	PFAM major facilitator superfamily MFS_1	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407	325.0
TH2_k127_8514146_5	Mediates influx of magnesium ions	K03284	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691	307.0
TH2_k127_8514146_6	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	K02867	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.000000000000000000000000000000000000000000000000000000000000000000001153	238.0
TH2_k127_8514146_7	Carotenoid biosynthesis protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000001292	244.0
TH2_k127_8514146_8	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	K01356	-	3.4.21.88	0.000000000000000000000000000000000000000000000000000000025	205.0
TH2_k127_8514146_9	MFS_1 like family	-	-	-	0.00000000000000000000000000000000000000000000000000001691	204.0
TH2_k127_8712858_0	Aminoglycoside 3-N-acetyltransferase	K00662	-	2.3.1.81	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005	332.0
TH2_k127_8712858_1	Two component transcriptional regulator, LuxR family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652	292.0
TH2_k127_8712858_2	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	K03790	-	2.3.1.128	0.000000000000000000000000000000000000000003658	161.0
TH2_k127_8766449_0	Belongs to the LDH MDH superfamily. LDH family	K00016	-	1.1.1.27	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123	305.0
TH2_k127_8766449_1	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	K03111	-	-	0.000000000000000000000000000000000006653	141.0
TH2_k127_8766449_2	PFAM Magnesium chelatase, subunit ChlI	K07391	-	-	0.0000002418	56.0
TH2_k127_8766449_3	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	K02316	-	-	0.0000003138	62.0
TH2_k127_8766449_4	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	K02338	-	2.7.7.7	0.000003124	58.0
TH2_k127_8775968_0	DNA replication proofreading	K02336,K06877	-	2.7.7.7	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209	427.0
TH2_k127_8775968_1	amine dehydrogenase activity	-	-	-	0.000000000000000000000000000000000000000000004554	186.0
TH2_k127_8775968_2	Domain of unknown function DUF11	-	-	-	0.000000000000000000000000000000000000000001092	179.0
TH2_k127_8775968_4	-	-	-	-	0.0000000000000001107	86.0
TH2_k127_8775968_5	-	-	-	-	0.000000000002485	71.0
TH2_k127_8775968_6	luxR family	-	-	-	0.0000000966	61.0
TH2_k127_8775968_8	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	-	-	-	0.0002115	50.0
TH2_k127_8775968_9	response regulator ArlR	K18941	-	-	0.0004357	50.0
TH2_k127_8777826_0	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	K02469	-	5.99.1.3	0.0	1114.0
TH2_k127_8777826_1	ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD	K16013	-	-	2.107e-246	803.0
TH2_k127_8777826_10	AAA domain, putative AbiEii toxin, Type IV TA system	K01990	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989	380.0
TH2_k127_8777826_11	Peptidoglycan-binding LysM	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002007	286.0
TH2_k127_8777826_12	Peptidase MA superfamily	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000002221	247.0
TH2_k127_8777826_13	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	K13292	-	-	0.00000000000000000000000000000000000000000000000000000000000000000003346	244.0
TH2_k127_8777826_14	SMART PDZ DHR GLGF domain protein	K11749	-	-	0.000000000000000000000000000000000000000000000000000000000000000004809	244.0
TH2_k127_8777826_15	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000001517	224.0
TH2_k127_8777826_16	pyridine nucleotide-disulphide oxidoreductase	-	-	-	0.000000000000000000000000000000000000000000000000000000000002363	224.0
TH2_k127_8777826_17	PFAM Dienelactone hydrolase	K01061	-	3.1.1.45	0.0000000000000000000000000000000000000000000000000000000001311	210.0
TH2_k127_8777826_18	PFAM Auxin Efflux Carrier	K07088	-	-	0.00000000000000000000000000000000000000000000000000001229	200.0
TH2_k127_8777826_19	biotin lipoate A B protein ligase	K03524	-	6.3.4.15	0.00000000000000000000000000000000000000000000000000001557	198.0
TH2_k127_8777826_2	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	K03628	-	-	2.224e-218	685.0
TH2_k127_8777826_20	ABC-2 family transporter protein	K01992	-	-	0.000000000000000000000000000000000000000008665	163.0
TH2_k127_8777826_22	transport system, permease component	K01992	-	-	0.00000000000000000000000000000002781	136.0
TH2_k127_8777826_23	-	-	-	-	0.0000000000000000000000000000002869	127.0
TH2_k127_8777826_24	-	-	-	-	0.000000000000000000000002202	111.0
TH2_k127_8777826_25	Transcriptional regulator	-	-	-	0.00000000000000000007828	96.0
TH2_k127_8777826_26	-	-	-	-	0.000000000000000001872	93.0
TH2_k127_8777826_27	PFAM acylphosphatase	K01512	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	0.000000000000002022	79.0
TH2_k127_8777826_28	META domain	-	-	-	0.0000000001028	68.0
TH2_k127_8777826_3	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	K01972	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	1.187e-207	670.0
TH2_k127_8777826_30	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	0.0005638	48.0
TH2_k127_8777826_4	GMC oxidoreductase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874	614.0
TH2_k127_8777826_5	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	K03553	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158	572.0
TH2_k127_8777826_6	Cytochrome bd-type quinol oxidase, subunit 1	K00425	-	1.10.3.14	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332	491.0
TH2_k127_8777826_7	Aminotransferase class-V	K01556	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.7.1.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896	483.0
TH2_k127_8777826_8	PFAM Cytochrome bd ubiquinol oxidase, subunit II	K00426	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528	427.0
TH2_k127_8777826_9	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	K01255	-	3.4.11.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329	427.0
TH2_k127_8784278_0	Alpha-L-fucosidase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198	447.0
TH2_k127_8784278_1	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002465	281.0
TH2_k127_8784278_2	L-rhamnose mutarotase	-	-	-	0.00000000000000000000000000000000000000000000000002397	180.0
TH2_k127_8784278_3	MatE	-	-	-	0.000000000000000000000000001303	115.0
TH2_k127_8819814_0	Glycosyltransferase 36 associated	-	-	-	0.0	1321.0
TH2_k127_8819814_1	PFAM glycoside hydrolase, family 3 domain protein	K05349	-	3.2.1.21	1.09e-225	710.0
TH2_k127_8819814_2	Glycoside hydrolase family 16	-	-	-	1.061e-224	736.0
TH2_k127_8819814_3	histidine kinase A domain protein	K02529,K07506	-	-	0.00000000000000000000000000000000000000000000000000000000000000000004113	236.0
TH2_k127_88686_0	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	K00525	-	1.17.4.1	0.0000000000000000000000000000000000000000000000000000000000000000000000945	258.0

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