Overview

ID MAG03908
Name TH2_bin.38
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA6898
Genus UBA6898
Species
Assembly information
Completeness (%) 92.75
Contamination (%) 5.5
GC content (%) 49.0
N50 (bp) 13,758
Genome size (bp) 2,150,745

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2112

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1102376_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.615e-297 932.0
TH2_k127_1102376_1 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000001357 117.0
TH2_k127_1102376_2 Haemolysin-type calcium-binding - - - 0.00000000000000000001794 106.0
TH2_k127_1102376_3 manually curated - - - 0.000000001233 61.0
TH2_k127_1124645_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.778e-251 794.0
TH2_k127_1124645_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.907e-231 729.0
TH2_k127_1124645_10 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 389.0
TH2_k127_1124645_11 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 355.0
TH2_k127_1124645_12 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 353.0
TH2_k127_1124645_13 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 321.0
TH2_k127_1124645_14 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 312.0
TH2_k127_1124645_15 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000004067 252.0
TH2_k127_1124645_16 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000002098 236.0
TH2_k127_1124645_17 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002374 235.0
TH2_k127_1124645_18 Lipid A core-O-antigen ligase-like enyme K18814 - - 0.00000000000000000000000000000000000000000000000000000000000001238 232.0
TH2_k127_1124645_19 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000004732 220.0
TH2_k127_1124645_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 8.953e-197 635.0
TH2_k127_1124645_20 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000001484 222.0
TH2_k127_1124645_21 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000003834 206.0
TH2_k127_1124645_22 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000009719 194.0
TH2_k127_1124645_23 sulfur carrier activity - - - 0.0000000000000000000000000000000000000000003745 160.0
TH2_k127_1124645_24 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000009613 151.0
TH2_k127_1124645_25 YbbR-like protein - - - 0.000000000000000000000000000000000000009919 153.0
TH2_k127_1124645_26 Glycine-zipper domain - - - 0.00000000000000000000000000000000000006208 156.0
TH2_k127_1124645_27 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000002602 119.0
TH2_k127_1124645_28 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000002664 113.0
TH2_k127_1124645_29 Glu-tRNAGln amidotransferase C subunit K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000002812 116.0
TH2_k127_1124645_3 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 532.0
TH2_k127_1124645_30 nucleotidyltransferase activity K07075 - - 0.000000000000000000000000007887 120.0
TH2_k127_1124645_31 - - - - 0.0000000000000000005499 91.0
TH2_k127_1124645_32 Domain of unknown function (DUF1858) - - - 0.00000000000000002447 83.0
TH2_k127_1124645_33 - - - - 0.000000000000196 79.0
TH2_k127_1124645_34 Sulfurtransferase TusA - - - 0.0000000006782 63.0
TH2_k127_1124645_36 - - - - 0.000000000983 62.0
TH2_k127_1124645_37 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000101 54.0
TH2_k127_1124645_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 528.0
TH2_k127_1124645_5 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 522.0
TH2_k127_1124645_6 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 497.0
TH2_k127_1124645_7 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 452.0
TH2_k127_1124645_8 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 422.0
TH2_k127_1124645_9 binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 417.0
TH2_k127_1126575_0 CAAX prenyl protease N-terminal, five membrane helices - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 481.0
TH2_k127_1126575_1 ABC-type polar amino acid transport system ATPase component K09972 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 299.0
TH2_k127_1126575_2 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000262 270.0
TH2_k127_1126575_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000005367 208.0
TH2_k127_1126575_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000002534 78.0
TH2_k127_1126575_5 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.00000000000000415 76.0
TH2_k127_1126575_6 - - - - 0.0000002052 55.0
TH2_k127_1126613_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1096.0
TH2_k127_1126613_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000358 243.0
TH2_k127_1126613_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000002454 213.0
TH2_k127_1126613_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001413 79.0
TH2_k127_1156154_0 PFAM peptidase K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 423.0
TH2_k127_1156154_1 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 325.0
TH2_k127_1156154_2 Mur ligase family, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 332.0
TH2_k127_1156154_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000003295 243.0
TH2_k127_1156154_4 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000001932 212.0
TH2_k127_1156154_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000005673 208.0
TH2_k127_1156154_6 Stringent starvation protein B K09985 - - 0.000000000000000000000000000006721 123.0
TH2_k127_1156154_7 Sporulation related domain - - - 0.00002414 55.0
TH2_k127_1156154_8 PFAM response regulator receiver K07662 - - 0.0004874 46.0
TH2_k127_1170182_0 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 282.0
TH2_k127_1170182_1 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000007793 216.0
TH2_k127_1170182_2 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000000004642 119.0
TH2_k127_1170182_3 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000009088 114.0
TH2_k127_1170182_4 Protein of unknown function (DUF1810) - - - 0.0000000004921 60.0
TH2_k127_120935_0 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 531.0
TH2_k127_120935_1 GHKL domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 523.0
TH2_k127_120935_10 PFAM Phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.0000000000000000000000009674 106.0
TH2_k127_120935_11 positive regulation of growth - - - 0.000000000000000000001488 95.0
TH2_k127_120935_12 - - - - 0.00007093 47.0
TH2_k127_120935_2 FAD binding domain K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 350.0
TH2_k127_120935_3 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001902 270.0
TH2_k127_120935_4 Zeta toxin - - - 0.000000000000000000000000000000000000000000000000000000000000000002079 230.0
TH2_k127_120935_5 Large family of predicted nucleotide-binding domains - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000001475 179.0
TH2_k127_120935_6 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000000592 171.0
TH2_k127_120935_7 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000001466 171.0
TH2_k127_120935_9 - - - - 0.000000000000000000000000009675 115.0
TH2_k127_1244674_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 573.0
TH2_k127_1244674_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 436.0
TH2_k127_1244674_2 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 366.0
TH2_k127_1244674_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000238 274.0
TH2_k127_1244674_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000008898 197.0
TH2_k127_1244674_5 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000009932 180.0
TH2_k127_1244674_6 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000001084 139.0
TH2_k127_1244674_7 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000002254 124.0
TH2_k127_1244674_8 cAMP biosynthetic process - - - 0.0000000002536 73.0
TH2_k127_1247222_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 8.722e-196 621.0
TH2_k127_1247222_1 lipoprotein localization to outer membrane K02004,K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 474.0
TH2_k127_1247222_2 Citrate synthase, C-terminal domain K01647,K01659 - 2.3.3.1,2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 398.0
TH2_k127_1247222_3 lipoprotein transporter activity K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 297.0
TH2_k127_1247222_4 - - - - 0.00000000000000000000000001222 113.0
TH2_k127_1247222_5 - - - - 0.00000008941 58.0
TH2_k127_1247222_6 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0001496 44.0
TH2_k127_1255122_0 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 364.0
TH2_k127_1255122_1 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000001869 243.0
TH2_k127_1255122_2 PFAM type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000000037 177.0
TH2_k127_1258540_0 NADH-quinone oxidoreductase K00341 - 1.6.5.3 2.388e-242 764.0
TH2_k127_1258540_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 598.0
TH2_k127_1258540_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 449.0
TH2_k127_1258540_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 405.0
TH2_k127_1258540_4 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 339.0
TH2_k127_1258540_5 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000003544 158.0
TH2_k127_1258540_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000001294 152.0
TH2_k127_1258540_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000001435 130.0
TH2_k127_1258540_8 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000003578 101.0
TH2_k127_1258540_9 SpoVT / AbrB like domain - - - 0.00000000000000003386 84.0
TH2_k127_1274079_0 4Fe-4S dicluster domain - - - 1.789e-303 936.0
TH2_k127_1274079_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 564.0
TH2_k127_1274079_10 - - - - 0.0000000000000000000000000000000000000000000000005686 177.0
TH2_k127_1274079_11 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.0000000000000000000000000000000000000000000008953 172.0
TH2_k127_1274079_12 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000001697 117.0
TH2_k127_1274079_13 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000009085 84.0
TH2_k127_1274079_14 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.00000000000000001329 87.0
TH2_k127_1274079_15 lyase activity - - - 0.00000000000001803 78.0
TH2_k127_1274079_16 DsrE/DsrF-like family K07235 - - 0.000000002534 63.0
TH2_k127_1274079_17 Belongs to the sulfur carrier protein TusA family - - - 0.000000008228 59.0
TH2_k127_1274079_18 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.0003627 47.0
TH2_k127_1274079_19 - - - - 0.0006055 49.0
TH2_k127_1274079_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 572.0
TH2_k127_1274079_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 523.0
TH2_k127_1274079_4 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 424.0
TH2_k127_1274079_5 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 334.0
TH2_k127_1274079_6 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000862 267.0
TH2_k127_1274079_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000008865 204.0
TH2_k127_1274079_8 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000007674 198.0
TH2_k127_1274079_9 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.0000000000000000000000000000000000000000000000000005422 188.0
TH2_k127_1275483_0 Surface antigen K07277 - - 1.832e-248 789.0
TH2_k127_1275483_1 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 1.259e-194 616.0
TH2_k127_1275483_10 Sulfate ABC transporter, permease K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 363.0
TH2_k127_1275483_11 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 283.0
TH2_k127_1275483_12 Catalyzes the synthesis of activated sulfate K00860 GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000002103 263.0
TH2_k127_1275483_13 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000004643 193.0
TH2_k127_1275483_14 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000000000004327 168.0
TH2_k127_1275483_15 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000007036 171.0
TH2_k127_1275483_16 Transcriptional regulator, BadM Rrf2 family - - - 0.00000000000000000000000000000000000000003401 158.0
TH2_k127_1275483_17 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.00000000000000000000000000000000008577 139.0
TH2_k127_1275483_18 - - - - 0.0000000000000001005 82.0
TH2_k127_1275483_2 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 595.0
TH2_k127_1275483_3 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 552.0
TH2_k127_1275483_4 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009958 552.0
TH2_k127_1275483_5 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 496.0
TH2_k127_1275483_6 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 471.0
TH2_k127_1275483_7 COG0555 ABC-type sulfate transport system, permease component K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 389.0
TH2_k127_1275483_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 385.0
TH2_k127_1275483_9 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 364.0
TH2_k127_128071_0 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 563.0
TH2_k127_128071_1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 521.0
TH2_k127_128071_10 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000001253 215.0
TH2_k127_128071_11 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000002433 206.0
TH2_k127_128071_12 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000004362 176.0
TH2_k127_128071_13 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000003984 174.0
TH2_k127_128071_14 YGGT family K02221 - - 0.000000000000000000000000000000004246 131.0
TH2_k127_128071_15 PFAM response regulator receiver - - - 0.0000000000000000000000000005669 117.0
TH2_k127_128071_16 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000002577 109.0
TH2_k127_128071_17 membrane - - - 0.00000000000000000000002363 111.0
TH2_k127_128071_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 463.0
TH2_k127_128071_3 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 453.0
TH2_k127_128071_4 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001482 283.0
TH2_k127_128071_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001596 276.0
TH2_k127_128071_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009716 246.0
TH2_k127_128071_7 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000673 233.0
TH2_k127_128071_8 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000004822 208.0
TH2_k127_128071_9 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000000000000000111 204.0
TH2_k127_1301156_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 373.0
TH2_k127_1301156_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 300.0
TH2_k127_1301156_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001035 259.0
TH2_k127_1301156_3 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000005377 202.0
TH2_k127_1301156_4 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000000001353 145.0
TH2_k127_1301156_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000001449 139.0
TH2_k127_1301156_6 Preprotein translocase SecG subunit K03075 - - 0.000000000000000002858 89.0
TH2_k127_1301156_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000007925 78.0
TH2_k127_1329282_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1112.0
TH2_k127_1329282_1 PFAM phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 527.0
TH2_k127_1329282_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 371.0
TH2_k127_1329282_3 membrane K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 368.0
TH2_k127_1329282_4 protein with SCP PR1 domains - - - 0.00000000000000000000000000000000000000001926 159.0
TH2_k127_1329282_6 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000857 94.0
TH2_k127_1329282_7 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000001565 72.0
TH2_k127_1329282_8 Binds directly to 16S ribosomal RNA K02968 - - 0.00000004114 58.0
TH2_k127_1332638_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 3.672e-228 724.0
TH2_k127_1332638_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 549.0
TH2_k127_1332638_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007173 267.0
TH2_k127_1332638_11 Diguanylate cyclase K21084 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000008646 282.0
TH2_k127_1332638_12 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002875 252.0
TH2_k127_1332638_13 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000000005325 195.0
TH2_k127_1332638_14 cobalamin synthesis protein - - - 0.0000000000000000000000000000000000000000002787 166.0
TH2_k127_1332638_15 Glutathione peroxidase - - - 0.0000000000000000000000000000000000005839 145.0
TH2_k127_1332638_16 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000001352 141.0
TH2_k127_1332638_17 - - - - 0.0000000000000000000000000008393 117.0
TH2_k127_1332638_18 Tetratricopeptide repeat - - - 0.000000000000002511 80.0
TH2_k127_1332638_19 protein transport across the cell outer membrane K02246,K02457,K02459,K02672,K08084 - - 0.00000000003137 71.0
TH2_k127_1332638_2 Associated with various cellular activities K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 366.0
TH2_k127_1332638_20 PFAM histidine kinase, HAMP region domain protein K03406 - - 0.00000000005553 64.0
TH2_k127_1332638_22 - - - - 0.00004662 53.0
TH2_k127_1332638_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 359.0
TH2_k127_1332638_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 349.0
TH2_k127_1332638_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080,K14082 - 2.1.1.246,2.1.1.247,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 345.0
TH2_k127_1332638_6 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 338.0
TH2_k127_1332638_7 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 338.0
TH2_k127_1332638_8 von Willebrand factor (vWF) type A domain K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 355.0
TH2_k127_1332638_9 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002102 273.0
TH2_k127_135678_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 391.0
TH2_k127_135678_1 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002764 239.0
TH2_k127_135678_2 - - - - 0.0000000000000000000000000000005166 126.0
TH2_k127_135678_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000006224 112.0
TH2_k127_135678_4 Methyltransferase - - - 0.0000000000006943 78.0
TH2_k127_1381122_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 367.0
TH2_k127_1381122_10 - - - - 0.00000000000000000000000000000000000000003343 157.0
TH2_k127_1381122_11 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000001732 100.0
TH2_k127_1381122_12 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000005396 69.0
TH2_k127_1381122_14 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 0.0000002755 59.0
TH2_k127_1381122_2 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 344.0
TH2_k127_1381122_3 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 334.0
TH2_k127_1381122_4 nitric oxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000009741 207.0
TH2_k127_1381122_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000003003 178.0
TH2_k127_1381122_6 MGS-like domain - - - 0.000000000000000000000000000000000000000000000003161 181.0
TH2_k127_1381122_7 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000000000000000000000003887 175.0
TH2_k127_1381122_8 Belongs to the Fur family K03711,K09825 - - 0.00000000000000000000000000000000000000000000006505 172.0
TH2_k127_1381122_9 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000001977 163.0
TH2_k127_1447499_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1223.0
TH2_k127_1447499_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 3.489e-272 849.0
TH2_k127_1447499_10 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 354.0
TH2_k127_1447499_11 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.000000000000000000000000000000000000001003 153.0
TH2_k127_1447499_12 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000006095 139.0
TH2_k127_1447499_13 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000004786 135.0
TH2_k127_1447499_14 - - - - 0.00000000000000000000000000002276 123.0
TH2_k127_1447499_15 LysM domain - - - 0.000000000000000000000000001245 124.0
TH2_k127_1447499_16 Transcriptional regulator - - - 0.0000000000000000000000001954 109.0
TH2_k127_1447499_17 nucleotidyltransferase activity - - - 0.00000000000000000000007784 104.0
TH2_k127_1447499_18 - - - - 0.00000000000000000000009663 97.0
TH2_k127_1447499_19 Universal stress protein family - - - 0.00000000000000006625 91.0
TH2_k127_1447499_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 3.609e-199 631.0
TH2_k127_1447499_20 Elongation factor SelB, winged helix K03833 - - 0.00000000001203 65.0
TH2_k127_1447499_3 Phosphoglycerate kinase K00927 - 2.7.2.3 1.902e-196 619.0
TH2_k127_1447499_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 500.0
TH2_k127_1447499_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 488.0
TH2_k127_1447499_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 430.0
TH2_k127_1447499_7 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 437.0
TH2_k127_1447499_8 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 398.0
TH2_k127_1447499_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 388.0
TH2_k127_1448832_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 512.0
TH2_k127_1448832_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 323.0
TH2_k127_1448832_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000001937 112.0
TH2_k127_1448832_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000004556 93.0
TH2_k127_1448832_4 - - - - 0.000000000001334 73.0
TH2_k127_1448832_5 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.0000001649 61.0
TH2_k127_1489953_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 477.0
TH2_k127_1489953_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 441.0
TH2_k127_1489953_10 (AIR) carboxylase K06898 - - 0.00000000000000000000000000009347 121.0
TH2_k127_1489953_11 Outer membrane protein (OmpH-like) K06142 - - 0.00000000001545 71.0
TH2_k127_1489953_12 - - - - 0.000000001887 62.0
TH2_k127_1489953_2 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 334.0
TH2_k127_1489953_3 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 316.0
TH2_k127_1489953_4 (Lipo)protein K04754 - - 0.0000000000000000000000000000000000000000000000000000000006744 216.0
TH2_k127_1489953_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000001107 205.0
TH2_k127_1489953_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000001001 212.0
TH2_k127_1489953_7 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000000000000000000004165 194.0
TH2_k127_1489953_8 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000002835 181.0
TH2_k127_1489953_9 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000002441 167.0
TH2_k127_1507827_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 459.0
TH2_k127_1507827_1 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 321.0
TH2_k127_1507827_10 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000004024 52.0
TH2_k127_1507827_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 313.0
TH2_k127_1507827_3 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000002671 245.0
TH2_k127_1507827_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000003286 237.0
TH2_k127_1507827_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000225 223.0
TH2_k127_1507827_6 Protein of unknown function (DUF4019) - - - 0.0000000000000000000000000000000000000002957 153.0
TH2_k127_1507827_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000004979 121.0
TH2_k127_1507827_8 MlaD protein K02067 - - 0.0000000000000000000000001033 117.0
TH2_k127_1507827_9 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000118 84.0
TH2_k127_1545974_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 568.0
TH2_k127_1545974_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 512.0
TH2_k127_1545974_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 310.0
TH2_k127_1545974_3 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003379 239.0
TH2_k127_155728_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1103.0
TH2_k127_155728_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 566.0
TH2_k127_155728_10 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000001858 269.0
TH2_k127_155728_11 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000001045 269.0
TH2_k127_155728_12 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000000000000000000000005432 207.0
TH2_k127_155728_13 Domain of unknown function (DUF3842) - - - 0.00000000000000000000000000000000000000000000000000005253 189.0
TH2_k127_155728_14 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000001093 190.0
TH2_k127_155728_15 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000000000001415 180.0
TH2_k127_155728_16 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000006654 160.0
TH2_k127_155728_17 Tetratricopeptide repeat - - - 0.000000000000000000000000003644 117.0
TH2_k127_155728_18 PFAM transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000003607 112.0
TH2_k127_155728_19 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000001437 83.0
TH2_k127_155728_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 576.0
TH2_k127_155728_3 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 397.0
TH2_k127_155728_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 386.0
TH2_k127_155728_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 386.0
TH2_k127_155728_6 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 337.0
TH2_k127_155728_7 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 336.0
TH2_k127_155728_8 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 340.0
TH2_k127_155728_9 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004548 302.0
TH2_k127_15656_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 542.0
TH2_k127_15656_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000003718 195.0
TH2_k127_15656_2 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000005824 128.0
TH2_k127_15656_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000002149 66.0
TH2_k127_1580912_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 3.692e-233 734.0
TH2_k127_1580912_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 541.0
TH2_k127_1580912_10 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000004534 181.0
TH2_k127_1580912_11 Cache domain - - - 0.0000000000000000000000000000000005986 141.0
TH2_k127_1580912_12 Rubrerythrin - - - 0.000000000000000000009749 98.0
TH2_k127_1580912_13 UPF0761 membrane protein K07058 - - 0.0000000000000000006915 96.0
TH2_k127_1580912_14 PBS lyase HEAT-like repeat - - - 0.0000000000000004251 85.0
TH2_k127_1580912_15 bacterial-type flagellum-dependent cell motility - - - 0.00002267 57.0
TH2_k127_1580912_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 352.0
TH2_k127_1580912_3 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 355.0
TH2_k127_1580912_4 PFAM MscS Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 342.0
TH2_k127_1580912_5 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 342.0
TH2_k127_1580912_6 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 345.0
TH2_k127_1580912_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002159 274.0
TH2_k127_1580912_8 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001357 253.0
TH2_k127_1580912_9 Redoxin K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000004128 235.0
TH2_k127_159426_0 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000001808 207.0
TH2_k127_159426_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0000000000000000000000000000000000000002963 150.0
TH2_k127_159426_2 exodeoxyribonuclease I activity - - - 0.0000000001766 65.0
TH2_k127_1597338_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 598.0
TH2_k127_1597338_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 595.0
TH2_k127_1597338_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 541.0
TH2_k127_1597338_3 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 331.0
TH2_k127_1597338_4 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002004 285.0
TH2_k127_1597338_5 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000366 264.0
TH2_k127_1597338_6 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003616 248.0
TH2_k127_1597338_7 PFAM Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000003988 240.0
TH2_k127_1597338_8 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000002505 163.0
TH2_k127_1620927_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.838e-203 644.0
TH2_k127_1620927_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 549.0
TH2_k127_1620927_2 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 503.0
TH2_k127_1620927_3 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 331.0
TH2_k127_1620927_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000002206 198.0
TH2_k127_1714080_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 8.059e-264 829.0
TH2_k127_1714080_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 1.839e-211 669.0
TH2_k127_1714080_2 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 454.0
TH2_k127_1714080_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 344.0
TH2_k127_1714080_4 - - - - 0.000006897 51.0
TH2_k127_1778173_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 627.0
TH2_k127_1778173_1 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 612.0
TH2_k127_1778173_10 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 297.0
TH2_k127_1778173_11 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006326 282.0
TH2_k127_1778173_12 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02236,K02278,K02506,K02654,K10966 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000003148 266.0
TH2_k127_1778173_13 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000003716 263.0
TH2_k127_1778173_14 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000001157 258.0
TH2_k127_1778173_15 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000001312 231.0
TH2_k127_1778173_16 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000001122 217.0
TH2_k127_1778173_17 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000009707 220.0
TH2_k127_1778173_18 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000008308 188.0
TH2_k127_1778173_19 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000403 171.0
TH2_k127_1778173_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 580.0
TH2_k127_1778173_20 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000006553 168.0
TH2_k127_1778173_21 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000001161 141.0
TH2_k127_1778173_22 - - - - 0.0000000000000000000000000000000005027 137.0
TH2_k127_1778173_24 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000004565 108.0
TH2_k127_1778173_25 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000005553 106.0
TH2_k127_1778173_26 Polymer-forming cytoskeletal - - - 0.00000000000000000006045 94.0
TH2_k127_1778173_27 Protein of unknown function DUF262 - - - 0.0000000000000000007544 97.0
TH2_k127_1778173_28 Protein of unknown function (DUF2905) - - - 0.00000000000000001865 85.0
TH2_k127_1778173_29 - - - - 0.000000000003413 70.0
TH2_k127_1778173_3 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 497.0
TH2_k127_1778173_30 - - - - 0.0000007305 54.0
TH2_k127_1778173_31 - - - - 0.000004537 50.0
TH2_k127_1778173_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 480.0
TH2_k127_1778173_5 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 453.0
TH2_k127_1778173_6 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 429.0
TH2_k127_1778173_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 336.0
TH2_k127_1778173_8 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 334.0
TH2_k127_1778173_9 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 331.0
TH2_k127_2006224_0 Belongs to the GPI family K01810 - 5.3.1.9 9.906e-268 833.0
TH2_k127_2006224_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 327.0
TH2_k127_2006224_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001163 234.0
TH2_k127_2006224_3 aminopeptidase N - - - 0.000000000000000000000000000000000000000000000007295 183.0
TH2_k127_2006224_4 - - - - 0.000000000000000000000000000000000000000000002184 169.0
TH2_k127_2006224_5 NADPH-dependent FMN reductase K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.0000001466 53.0
TH2_k127_2023963_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.469e-274 861.0
TH2_k127_2023963_1 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000001994 185.0
TH2_k127_2023963_2 - - - - 0.0000000000000009189 80.0
TH2_k127_218355_0 TRCF K03723 - - 3.852e-228 746.0
TH2_k127_218355_1 PAS domain K09155 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 466.0
TH2_k127_218355_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 419.0
TH2_k127_218355_3 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 380.0
TH2_k127_218355_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000005731 248.0
TH2_k127_218355_5 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000002548 148.0
TH2_k127_218355_6 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000003147 118.0
TH2_k127_218355_7 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000346 110.0
TH2_k127_218355_8 - - - - 0.0000931 46.0
TH2_k127_2202747_0 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 520.0
TH2_k127_2202747_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 296.0
TH2_k127_2202747_2 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000001266 201.0
TH2_k127_2202747_3 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000000003359 67.0
TH2_k127_2237113_0 PD-(D/E)XK nuclease superfamily - - - 3.297e-225 733.0
TH2_k127_2237113_1 Belongs to the helicase family. UvrD subfamily - - - 7.494e-216 704.0
TH2_k127_2239316_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 1.028e-245 781.0
TH2_k127_2239316_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000803 51.0
TH2_k127_2296578_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 437.0
TH2_k127_2296578_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000001247 114.0
TH2_k127_2296578_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000007338 75.0
TH2_k127_2296578_3 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00003017 46.0
TH2_k127_2300125_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 497.0
TH2_k127_2300125_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000001213 208.0
TH2_k127_2300125_2 shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000005819 144.0
TH2_k127_2354075_0 nodulation K00612 - - 2.351e-262 821.0
TH2_k127_2354075_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 3.275e-235 734.0
TH2_k127_2354075_10 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001439 281.0
TH2_k127_2354075_11 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003751 271.0
TH2_k127_2354075_12 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001083 239.0
TH2_k127_2354075_13 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000001993 226.0
TH2_k127_2354075_14 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000006644 224.0
TH2_k127_2354075_15 - - - - 0.0000000000000000000000000000000000000000000000000000000001749 210.0
TH2_k127_2354075_16 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000001209 213.0
TH2_k127_2354075_17 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000001139 199.0
TH2_k127_2354075_18 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000985 192.0
TH2_k127_2354075_19 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000001771 183.0
TH2_k127_2354075_2 ABC transporter transmembrane region K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 519.0
TH2_k127_2354075_20 AMP-binding enzyme C-terminal domain K16029 - - 0.00000000000000000000000000000000000000000000000003867 197.0
TH2_k127_2354075_21 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000002373 188.0
TH2_k127_2354075_22 Membrane protein involved in D-alanine export - - - 0.0000000000000000000000000000000000000001533 167.0
TH2_k127_2354075_23 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000003996 164.0
TH2_k127_2354075_24 Domain of unknown function (DUF386) - - - 0.0000000000000000000000000000005432 127.0
TH2_k127_2354075_25 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.000000000000000001491 97.0
TH2_k127_2354075_26 PFAM Sulfotransferase domain - - - 0.00000000000000007083 90.0
TH2_k127_2354075_27 - - - - 0.00000000000001689 74.0
TH2_k127_2354075_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 402.0
TH2_k127_2354075_30 PFAM Glycosyl transferase, group 1 K02844 - - 0.0000005097 53.0
TH2_k127_2354075_31 Phosphopantetheine attachment site - - - 0.000001833 53.0
TH2_k127_2354075_4 COG2513 PEP phosphonomutase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 372.0
TH2_k127_2354075_5 Domain of unknown function (DUF3413) K07014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 377.0
TH2_k127_2354075_6 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 353.0
TH2_k127_2354075_7 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 302.0
TH2_k127_2354075_8 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 287.0
TH2_k127_2354075_9 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005686 280.0
TH2_k127_2370817_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 580.0
TH2_k127_2370817_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 580.0
TH2_k127_2370817_10 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000003481 232.0
TH2_k127_2370817_11 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000007974 226.0
TH2_k127_2370817_12 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000005997 222.0
TH2_k127_2370817_13 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000004754 175.0
TH2_k127_2370817_15 - - - - 0.0000006713 56.0
TH2_k127_2370817_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 493.0
TH2_k127_2370817_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 488.0
TH2_k127_2370817_4 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 456.0
TH2_k127_2370817_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 385.0
TH2_k127_2370817_6 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 310.0
TH2_k127_2370817_7 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009431 290.0
TH2_k127_2370817_8 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001117 289.0
TH2_k127_2370817_9 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002126 285.0
TH2_k127_2380683_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 608.0
TH2_k127_2380683_1 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 451.0
TH2_k127_2380683_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 407.0
TH2_k127_2380683_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000002099 241.0
TH2_k127_2380683_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000001377 150.0
TH2_k127_2384506_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 3.816e-198 622.0
TH2_k127_2384506_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 499.0
TH2_k127_2384506_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 286.0
TH2_k127_2384506_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000002585 171.0
TH2_k127_2384506_4 PFAM Roadblock LC7 family protein - - - 0.000000003542 58.0
TH2_k127_2409959_0 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 324.0
TH2_k127_2409959_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000002046 231.0
TH2_k127_2409959_2 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000007115 218.0
TH2_k127_2409959_3 Histidine kinase - - - 0.0000000000000000000004617 100.0
TH2_k127_2413528_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 8.147e-212 663.0
TH2_k127_2413528_1 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 508.0
TH2_k127_2413528_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000001103 160.0
TH2_k127_2416581_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 447.0
TH2_k127_2416581_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 358.0
TH2_k127_2416581_2 SPTR Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000003323 160.0
TH2_k127_2416581_3 PFAM CBS domain K07182 - - 0.00000000000000000001417 97.0
TH2_k127_2416581_4 histidine kinase A domain protein - - - 0.0000001042 59.0
TH2_k127_2416581_5 signal transduction protein - - - 0.00008191 48.0
TH2_k127_2421881_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.913e-239 751.0
TH2_k127_2421881_1 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 434.0
TH2_k127_2421881_10 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005662 265.0
TH2_k127_2421881_11 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003002 256.0
TH2_k127_2421881_12 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004988 242.0
TH2_k127_2421881_13 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000004494 228.0
TH2_k127_2421881_14 photoreceptor activity K02007,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000001093 237.0
TH2_k127_2421881_15 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000001701 218.0
TH2_k127_2421881_16 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000000000009736 205.0
TH2_k127_2421881_17 Oxidoreductase NAD-binding domain K02823 - - 0.000000000000000000000000000000000000000000000000004357 190.0
TH2_k127_2421881_18 response regulator K02485 - - 0.0000000000000000000000000000000000000000000000005226 178.0
TH2_k127_2421881_19 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000003035 112.0
TH2_k127_2421881_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 422.0
TH2_k127_2421881_20 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000002026 98.0
TH2_k127_2421881_21 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.000000000000000004758 83.0
TH2_k127_2421881_22 Uncharacterized integral membrane protein (DUF2301) - - - 0.0000000002107 69.0
TH2_k127_2421881_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 411.0
TH2_k127_2421881_4 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 392.0
TH2_k127_2421881_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 350.0
TH2_k127_2421881_6 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 323.0
TH2_k127_2421881_7 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 326.0
TH2_k127_2421881_8 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 297.0
TH2_k127_2421881_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 302.0
TH2_k127_2463373_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.726e-277 861.0
TH2_k127_2463373_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.154e-195 616.0
TH2_k127_2463373_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000002715 181.0
TH2_k127_2463373_11 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000008994 129.0
TH2_k127_2463373_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000002385 128.0
TH2_k127_2463373_13 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000239 119.0
TH2_k127_2463373_14 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000003938 106.0
TH2_k127_2463373_15 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.000000000000000000001004 98.0
TH2_k127_2463373_16 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000001377 86.0
TH2_k127_2463373_17 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000002781 64.0
TH2_k127_2463373_2 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 577.0
TH2_k127_2463373_3 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 461.0
TH2_k127_2463373_4 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 317.0
TH2_k127_2463373_5 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006456 276.0
TH2_k127_2463373_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000002941 251.0
TH2_k127_2463373_7 NOG31153 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000000001071 250.0
TH2_k127_2463373_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000001099 233.0
TH2_k127_2463373_9 riboflavin synthase, alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000006996 210.0
TH2_k127_2534777_0 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 571.0
TH2_k127_2534777_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003606 246.0
TH2_k127_2534777_2 nucleotide metabolic process - - - 0.00000000000000000000000000000000000000008817 160.0
TH2_k127_2534777_3 Cache domain K02482 - 2.7.13.3 0.00000000000000003348 81.0
TH2_k127_2551231_0 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000092 290.0
TH2_k127_2551231_1 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002314 285.0
TH2_k127_2551231_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000001139 87.0
TH2_k127_2551231_4 - - - - 0.000000000003289 72.0
TH2_k127_2551231_5 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.000000000008626 78.0
TH2_k127_2598772_0 Glycosyltransferase like family 2 - - - 3.914e-309 971.0
TH2_k127_2598772_1 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 533.0
TH2_k127_2598772_2 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 452.0
TH2_k127_2598772_3 sulfuric ester hydrolase activity K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 414.0
TH2_k127_2598772_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 321.0
TH2_k127_2598772_5 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 319.0
TH2_k127_2598772_6 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000006049 259.0
TH2_k127_2598772_7 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.000000000001212 68.0
TH2_k127_2600537_0 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 327.0
TH2_k127_2600537_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002671 261.0
TH2_k127_2600537_2 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000001155 201.0
TH2_k127_2600537_3 - - - - 0.0000000000000000000000001587 108.0
TH2_k127_2703992_0 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.000000000000000000000000000000000000000009552 156.0
TH2_k127_2703992_1 RNase H - - - 0.000000000000000001 93.0
TH2_k127_2708344_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 599.0
TH2_k127_2708344_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 302.0
TH2_k127_2708344_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 287.0
TH2_k127_2708344_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 294.0
TH2_k127_2708344_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001753 246.0
TH2_k127_2708344_5 UTRA K03710 - - 0.00000000000000000000000000000000007458 143.0
TH2_k127_2708344_6 AMP binding - - - 0.0000000000000000000000000000000001259 137.0
TH2_k127_2708344_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000001708 135.0
TH2_k127_2708344_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000005166 108.0
TH2_k127_2715281_0 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001715 274.0
TH2_k127_2715281_1 Universal stress protein family K07090 - - 0.000000000000000000000000000000000000000001851 170.0
TH2_k127_2715281_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000005839 127.0
TH2_k127_2745930_0 Putative peptidoglycan binding domain K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 495.0
TH2_k127_2745930_1 UDP-N-acetylmuramyl pentapeptide K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 329.0
TH2_k127_2745930_2 Type II secretion system protein B K02451 - - 0.0000000000000149 83.0
TH2_k127_2800965_0 Seven times multi-haem cytochrome CxxCH - - - 3.048e-198 624.0
TH2_k127_2800965_1 - - - - 0.00000000000000000000000000000000000000000000000000000000002765 213.0
TH2_k127_2800965_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000002977 160.0
TH2_k127_2800965_3 cytochrome - - - 0.000000000000000000001855 95.0
TH2_k127_28937_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 492.0
TH2_k127_3060638_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 8.075e-202 643.0
TH2_k127_3060638_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 510.0
TH2_k127_3060638_2 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 456.0
TH2_k127_3060638_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 414.0
TH2_k127_3060638_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 370.0
TH2_k127_3060638_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 326.0
TH2_k127_3060638_6 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000001561 245.0
TH2_k127_3060638_7 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000006238 179.0
TH2_k127_3060638_8 Male sterility protein - - - 0.0000000000000000000000000000009991 134.0
TH2_k127_3118885_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 1.609e-238 753.0
TH2_k127_3118885_1 GAF domain - - - 8.189e-205 688.0
TH2_k127_3118885_10 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000003094 190.0
TH2_k127_3118885_11 Domain of unknown function (DUF4124) K08309 - - 0.00000000000000000000000000000000000000000005736 168.0
TH2_k127_3118885_12 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000001583 161.0
TH2_k127_3118885_13 phosphorelay signal transduction system - - - 0.000000000000000000000000000000003274 137.0
TH2_k127_3118885_14 Putative regulatory protein - - - 0.0000000000000000000002716 100.0
TH2_k127_3118885_15 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000001508 81.0
TH2_k127_3118885_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 529.0
TH2_k127_3118885_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 437.0
TH2_k127_3118885_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 376.0
TH2_k127_3118885_5 PFAM ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 346.0
TH2_k127_3118885_6 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 311.0
TH2_k127_3118885_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 305.0
TH2_k127_3118885_8 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002578 252.0
TH2_k127_3118885_9 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000001485 242.0
TH2_k127_3136318_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 564.0
TH2_k127_3136318_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 514.0
TH2_k127_3136318_2 Alanine-glyoxylate amino-transferase K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 499.0
TH2_k127_3136318_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000285 200.0
TH2_k127_3136318_4 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000007486 204.0
TH2_k127_3136318_5 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000002353 191.0
TH2_k127_3136318_6 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000008162 134.0
TH2_k127_3136318_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000008838 103.0
TH2_k127_3136318_8 - - - - 0.00000000001482 66.0
TH2_k127_3181024_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1209.0
TH2_k127_3181024_1 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 432.0
TH2_k127_3181024_10 Ribosomal RNA adenine dimethylase - - - 0.000000000005034 73.0
TH2_k127_3181024_11 COG2200 FOG EAL domain K20963 - 3.1.4.52 0.0000007681 58.0
TH2_k127_3181024_12 - - - - 0.0005734 46.0
TH2_k127_3181024_2 PFAM major facilitator superfamily MFS_1 K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001143 256.0
TH2_k127_3181024_3 - - - - 0.00000000000000000000000000000000000000000000000001019 186.0
TH2_k127_3181024_4 DoxX K15977 - - 0.000000000000000000000000000000000000000000000001683 176.0
TH2_k127_3181024_5 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.00000000000000000000000000000000000000000000004592 179.0
TH2_k127_3181024_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000002371 157.0
TH2_k127_3181024_7 Membrane - - - 0.0000000000000000000000623 107.0
TH2_k127_3181024_8 Protein of unknown function (DUF1189) - - - 0.00000000000000000009479 99.0
TH2_k127_3181024_9 - - - - 0.00000000000000008583 81.0
TH2_k127_3203625_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1630.0
TH2_k127_3203625_1 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 383.0
TH2_k127_3203625_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004935 259.0
TH2_k127_3203625_3 transcriptional regulator - - - 0.000000000000000000000001835 110.0
TH2_k127_3236060_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 447.0
TH2_k127_3236060_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 353.0
TH2_k127_3236060_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000001846 177.0
TH2_k127_3236060_3 Radical SAM domain protein - - - 0.00000000001561 69.0
TH2_k127_3236060_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0032940,GO:0033036,GO:0034613,GO:0042597,GO:0042886,GO:0042953,GO:0042954,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051641,GO:0070727,GO:0071702,GO:0071705,GO:0072321,GO:0072322,GO:0072323,GO:0072657 - 0.00000000158 66.0
TH2_k127_3236060_5 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000001733 59.0
TH2_k127_331409_0 Elongation factor G, domain IV K02355 - - 5.407e-291 908.0
TH2_k127_331409_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 2.501e-244 765.0
TH2_k127_331409_10 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000001171 190.0
TH2_k127_331409_11 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000002661 183.0
TH2_k127_331409_12 - - - - 0.000000000000000000000000000000000000000000000003315 176.0
TH2_k127_331409_13 PFAM pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000000127 162.0
TH2_k127_331409_14 Cytochrome P460 - - - 0.000000000000000000000000000000000000000005825 160.0
TH2_k127_331409_15 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000008047 156.0
TH2_k127_331409_16 ferredoxin-thioredoxin reductase activity - - - 0.000000000000000000000000000000000000003219 148.0
TH2_k127_331409_17 methyltransferase activity - - - 0.00000000000000000000000000000000000009236 149.0
TH2_k127_331409_18 IMP dehydrogenase activity - - - 0.000000000000000000000000000009988 124.0
TH2_k127_331409_19 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000000000000000003046 117.0
TH2_k127_331409_2 DNA photolyase K01669 - 4.1.99.3 7.359e-196 620.0
TH2_k127_331409_20 Cold shock K03704 - - 0.000000000000000000000000271 106.0
TH2_k127_331409_21 response regulator, receiver - - - 0.000000000000000000000001509 107.0
TH2_k127_331409_22 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.00000000000000000000009189 102.0
TH2_k127_331409_23 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.0000000000000000000001158 99.0
TH2_k127_331409_24 - - - - 0.0000000000000000000009324 97.0
TH2_k127_331409_25 cyclic nucleotide binding K00384,K01420 - 1.8.1.9 0.0000000000000000000158 96.0
TH2_k127_331409_26 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000004672 91.0
TH2_k127_331409_27 Histidine kinase - - - 0.00000000003566 72.0
TH2_k127_331409_28 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.0000000001188 66.0
TH2_k127_331409_29 - - - - 0.000000003693 64.0
TH2_k127_331409_3 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 606.0
TH2_k127_331409_30 - - - - 0.00000002807 57.0
TH2_k127_331409_32 PFAM NAD-dependent epimerase dehydratase - - - 0.00001324 50.0
TH2_k127_331409_4 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 453.0
TH2_k127_331409_5 kinase activity K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 301.0
TH2_k127_331409_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009904 276.0
TH2_k127_331409_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002588 266.0
TH2_k127_331409_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000001077 242.0
TH2_k127_331409_9 DNA-binding transcription factor activity K03710 - - 0.0000000000000000000000000000000000000000000000000000000000001579 220.0
TH2_k127_3344364_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 373.0
TH2_k127_3344364_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 347.0
TH2_k127_3344364_2 ABC1 family - - - 0.000000000000000000000000000000000000000000000000003333 190.0
TH2_k127_3344364_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000007517 177.0
TH2_k127_3344364_4 - - - - 0.000000000000000000000000000000000000008275 154.0
TH2_k127_3344364_5 radical SAM domain protein - - - 0.0000000000000000000000000000002942 136.0
TH2_k127_3344364_6 TIGRFAM Protein of - - - 0.000000000000000000000001196 108.0
TH2_k127_3344364_7 S4 domain K14761 - - 0.000000000000000000009283 93.0
TH2_k127_3344364_8 PilZ domain - - - 0.0003447 52.0
TH2_k127_3365708_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 496.0
TH2_k127_3365708_1 ABC transporter (Permease K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 355.0
TH2_k127_3365708_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000104 277.0
TH2_k127_3365708_3 - - - - 0.0000344 48.0
TH2_k127_3384442_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 320.0
TH2_k127_3384442_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001941 261.0
TH2_k127_3396581_0 Conserved carboxylase domain K01571,K01960,K03416 - 2.1.3.1,4.1.1.3,6.4.1.1 6.871e-307 946.0
TH2_k127_3396581_1 PFAM carboxyl transferase K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 3.358e-275 853.0
TH2_k127_3396581_2 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 552.0
TH2_k127_3396581_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 533.0
TH2_k127_3396581_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 479.0
TH2_k127_3396581_5 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000003736 102.0
TH2_k127_3411428_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 1.952e-216 706.0
TH2_k127_3411428_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 574.0
TH2_k127_3411428_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 444.0
TH2_k127_3411428_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000231 201.0
TH2_k127_3429286_0 Cytochrome C and Quinol oxidase polypeptide I K04561 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0055114 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 411.0
TH2_k127_3429286_1 PFAM Cytochrome b5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 298.0
TH2_k127_3429286_2 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000001697 141.0
TH2_k127_3429286_3 4Fe-4S binding domain - - - 0.000008926 51.0
TH2_k127_3430458_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 562.0
TH2_k127_3430458_1 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 548.0
TH2_k127_3430458_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 325.0
TH2_k127_3430458_3 4Fe-4S binding domain - - - 0.0000000000001138 72.0
TH2_k127_3430458_4 Recombinase zinc beta ribbon domain - - - 0.0000264 51.0
TH2_k127_3488086_0 Major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 404.0
TH2_k127_3488086_1 Protein of unknown function (DUF1460) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001023 258.0
TH2_k127_3488086_2 4Fe-4S binding domain - - - 0.00000000000000000000008761 108.0
TH2_k127_3505695_0 40-residue yvtn family beta-propeller repeat protein - - - 4.061e-211 664.0
TH2_k127_3505695_1 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 335.0
TH2_k127_3505695_2 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001133 263.0
TH2_k127_3505695_3 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000973 121.0
TH2_k127_3505695_4 OsmC-like protein - - - 0.000000000000000000003674 99.0
TH2_k127_3505695_5 Belongs to the peptidase M48B family K03799 - - 0.00000000006531 63.0
TH2_k127_3506719_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 6.076e-224 712.0
TH2_k127_3506719_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 445.0
TH2_k127_3506719_10 TM2 domain - - - 0.0000000000000000000000000001492 118.0
TH2_k127_3506719_11 FR47-like protein - - - 0.000000000000000009972 85.0
TH2_k127_3506719_12 - - - - 0.0000000000001016 75.0
TH2_k127_3506719_13 Belongs to the 'phage' integrase family - - - 0.0000000000001105 75.0
TH2_k127_3506719_14 PFAM Nitrate reductase gamma subunit - - - 0.000000005965 65.0
TH2_k127_3506719_15 4Fe-4S double cluster binding domain - - - 0.0000009963 51.0
TH2_k127_3506719_17 Rubrerythrin - - - 0.0002372 48.0
TH2_k127_3506719_2 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 349.0
TH2_k127_3506719_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 328.0
TH2_k127_3506719_4 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000032 293.0
TH2_k127_3506719_5 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000004299 236.0
TH2_k127_3506719_6 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000001794 236.0
TH2_k127_3506719_7 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000001848 200.0
TH2_k127_3506719_8 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000000000000000000001033 176.0
TH2_k127_3506719_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000005871 126.0
TH2_k127_351652_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 467.0
TH2_k127_351652_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 403.0
TH2_k127_351652_2 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000002109 173.0
TH2_k127_351652_3 DSBA-like thioredoxin domain - - - 0.0005067 45.0
TH2_k127_352571_0 O-methyltransferase activity - - - 6.625e-212 678.0
TH2_k127_352571_1 SMART Elongator protein 3 MiaB NifB - - - 9.93e-204 649.0
TH2_k127_352571_10 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003863 243.0
TH2_k127_352571_11 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004099 233.0
TH2_k127_352571_12 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000000006989 121.0
TH2_k127_352571_14 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000004093 72.0
TH2_k127_352571_15 Universal stress protein - - - 0.000001617 57.0
TH2_k127_352571_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 517.0
TH2_k127_352571_3 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000987 413.0
TH2_k127_352571_4 S1 domain K00243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 335.0
TH2_k127_352571_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 331.0
TH2_k127_352571_6 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 340.0
TH2_k127_352571_7 TIGRFAM peptidase T-like protein K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 295.0
TH2_k127_352571_8 Oligoendopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006909 284.0
TH2_k127_352571_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 267.0
TH2_k127_3533232_0 DEAD DEAH box helicase K06877 - - 3.876e-215 691.0
TH2_k127_3533232_1 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000001103 154.0
TH2_k127_3533232_2 Plasmid maintenance system killer K07334 - - 0.000000000000000000000000000000000003001 139.0
TH2_k127_3533232_3 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000000000000004454 109.0
TH2_k127_3533232_4 Protein of unknown function, DUF255 - - - 0.0001659 47.0
TH2_k127_353375_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.601e-225 704.0
TH2_k127_353375_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 5.74e-217 683.0
TH2_k127_353375_10 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - - 0.00000006702 61.0
TH2_k127_353375_2 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 504.0
TH2_k127_353375_3 B12 binding domain K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 310.0
TH2_k127_353375_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000002167 198.0
TH2_k127_353375_5 retrograde transport, endosome to Golgi K07095 - - 0.000000000000000000000000000000000000000000000001067 178.0
TH2_k127_353375_6 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000607 164.0
TH2_k127_353375_7 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000001202 148.0
TH2_k127_353375_8 Chromate K07240 - - 0.0000000000000000000000000000005228 133.0
TH2_k127_353375_9 Psort location CytoplasmicMembrane, score K07240 - - 0.000000000000000000000000000001015 128.0
TH2_k127_3566523_0 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 496.0
TH2_k127_3566523_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 478.0
TH2_k127_3566523_10 - - - - 0.000000000000000000000004235 108.0
TH2_k127_3566523_11 COG3291 FOG PKD repeat - - - 0.0000000000008227 81.0
TH2_k127_3566523_2 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 432.0
TH2_k127_3566523_3 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006577 259.0
TH2_k127_3566523_4 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000004908 237.0
TH2_k127_3566523_5 Peptidase S24-like K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000005621 218.0
TH2_k127_3566523_6 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000242 229.0
TH2_k127_3566523_7 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000003264 216.0
TH2_k127_3566523_8 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000003206 198.0
TH2_k127_3566523_9 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000003777 139.0
TH2_k127_3592494_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 579.0
TH2_k127_3599462_0 CHASE2 K01768 - 4.6.1.1 1.037e-233 745.0
TH2_k127_3599462_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.054e-233 733.0
TH2_k127_3599462_10 Belongs to the sulfur carrier protein TusA family - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000000004267 73.0
TH2_k127_3599462_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 2.527e-217 679.0
TH2_k127_3599462_3 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 599.0
TH2_k127_3599462_4 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 553.0
TH2_k127_3599462_5 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 508.0
TH2_k127_3599462_6 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 286.0
TH2_k127_3599462_7 ThiS family K03636 - - 0.0000000000000000000000000000000007285 133.0
TH2_k127_3599462_8 NIL - - - 0.0000000000000000000000000003086 115.0
TH2_k127_3599462_9 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000001803 115.0
TH2_k127_3642613_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1057.0
TH2_k127_3642613_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 425.0
TH2_k127_3642613_10 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000001087 205.0
TH2_k127_3642613_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000007088 194.0
TH2_k127_3642613_12 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000005817 189.0
TH2_k127_3642613_14 ECF sigma factor K03088 - - 0.00000000000000000000000000000000001702 142.0
TH2_k127_3642613_15 Protein of unknown function (DUF3592) - - - 0.000000000000002143 87.0
TH2_k127_3642613_16 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000004369 81.0
TH2_k127_3642613_17 - - - - 0.000000005066 61.0
TH2_k127_3642613_18 Belongs to the universal stress protein A family - - - 0.0000001621 60.0
TH2_k127_3642613_19 Integral membrane protein - - - 0.000004496 55.0
TH2_k127_3642613_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 425.0
TH2_k127_3642613_20 Protein of unknown function (DUF3106) - - - 0.00007258 52.0
TH2_k127_3642613_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 416.0
TH2_k127_3642613_4 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 374.0
TH2_k127_3642613_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 297.0
TH2_k127_3642613_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000001458 239.0
TH2_k127_3642613_7 phosphorelay signal transduction system K02535,K13599,K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000007251 211.0
TH2_k127_3642613_8 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000001024 210.0
TH2_k127_3642613_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000001245 202.0
TH2_k127_3693666_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.918e-264 826.0
TH2_k127_3693666_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 318.0
TH2_k127_3693666_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000003254 236.0
TH2_k127_3693666_3 protein-disulfide reductase activity - - - 0.0000000000000000000006331 99.0
TH2_k127_3693666_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000009377 68.0
TH2_k127_3693666_5 - - - - 0.000001122 58.0
TH2_k127_369420_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 504.0
TH2_k127_369420_1 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 309.0
TH2_k127_369420_2 methyltransferase - - - 0.000000000000000000000000000000000001162 147.0
TH2_k127_369420_3 Tetratricopeptide repeat - - - 0.000000000000001313 83.0
TH2_k127_369420_4 4Fe-4S binding domain - - - 0.000000000000001426 78.0
TH2_k127_369420_5 CYTH K05873 - 4.6.1.1 0.000000000001988 74.0
TH2_k127_369420_6 Cupin 2, conserved barrel domain protein - - - 0.000000000003827 70.0
TH2_k127_369446_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 329.0
TH2_k127_369446_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000007229 231.0
TH2_k127_3717007_0 Heat shock 70 kDa protein K04043 - - 1.181e-316 979.0
TH2_k127_3717007_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 437.0
TH2_k127_3717007_10 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000006275 104.0
TH2_k127_3717007_11 anti-sigma regulatory factor K04757 - 2.7.11.1 0.000000000000000000000131 102.0
TH2_k127_3717007_12 antisigma factor binding K04749 - - 0.0000000000000000001901 91.0
TH2_k127_3717007_13 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000009645 87.0
TH2_k127_3717007_2 TrkA-N domain K03455,K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 382.0
TH2_k127_3717007_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 299.0
TH2_k127_3717007_4 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001116 273.0
TH2_k127_3717007_5 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000964 233.0
TH2_k127_3717007_6 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000002061 246.0
TH2_k127_3717007_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000001694 179.0
TH2_k127_3717007_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000002478 154.0
TH2_k127_3717007_9 AI-2E family transporter - - - 0.00000000000000000000000000000000002861 148.0
TH2_k127_3724288_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1079.0
TH2_k127_3724288_1 Endoribonuclease that initiates mRNA decay K18682 - - 1.895e-208 661.0
TH2_k127_3724288_10 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000001946 192.0
TH2_k127_3724288_11 Histidine kinase - - - 0.00000000000000000000000000000000000002321 148.0
TH2_k127_3724288_12 protein secretion K02460 - - 0.000000000000000000000000000002509 132.0
TH2_k127_3724288_13 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000003222 123.0
TH2_k127_3724288_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000002236 92.0
TH2_k127_3724288_15 Fimbrial assembly protein (PilN) K02461 - - 0.0000000008316 71.0
TH2_k127_3724288_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 548.0
TH2_k127_3724288_3 AAA ATPase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 460.0
TH2_k127_3724288_4 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 378.0
TH2_k127_3724288_5 Bacterial type II and III secretion system protein K02453,K03219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 351.0
TH2_k127_3724288_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 324.0
TH2_k127_3724288_7 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 315.0
TH2_k127_3724288_8 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001377 276.0
TH2_k127_3724288_9 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002116 276.0
TH2_k127_3842025_0 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000284 285.0
TH2_k127_3842025_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000002581 258.0
TH2_k127_3842025_2 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.0000000000000000000000000000000001697 146.0
TH2_k127_38588_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.898e-262 817.0
TH2_k127_38588_1 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 3.865e-230 736.0
TH2_k127_38588_2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 391.0
TH2_k127_38588_3 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 286.0
TH2_k127_38588_4 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001841 280.0
TH2_k127_38588_5 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000000000006471 218.0
TH2_k127_3993596_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 9.617e-225 702.0
TH2_k127_3993596_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 526.0
TH2_k127_3993596_2 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000001051 244.0
TH2_k127_3993596_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001244 219.0
TH2_k127_4009960_0 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 526.0
TH2_k127_4009960_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 451.0
TH2_k127_4009960_10 Domain of unknown function (DUF4410) - - - 0.000000000000000000001431 103.0
TH2_k127_4009960_11 Cysteine-rich small domain - - - 0.000000000000000001631 87.0
TH2_k127_4009960_12 response regulator, receiver K03413 - - 0.00000000000000000207 90.0
TH2_k127_4009960_13 FecR protein - - - 0.00000000001493 74.0
TH2_k127_4009960_14 Multidrug transporter - - - 0.00000004563 59.0
TH2_k127_4009960_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000003104 63.0
TH2_k127_4009960_16 PFAM TPR repeat-containing protein - - - 0.0000003284 63.0
TH2_k127_4009960_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 318.0
TH2_k127_4009960_3 Phospholipase, patatin family K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004884 281.0
TH2_k127_4009960_4 - - - - 0.00000000000000000000000000000000000000000000000894 174.0
TH2_k127_4009960_5 Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000004032 176.0
TH2_k127_4009960_6 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000004237 153.0
TH2_k127_4009960_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000281 149.0
TH2_k127_4009960_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000002604 139.0
TH2_k127_4009960_9 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000004453 137.0
TH2_k127_4017588_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1224.0
TH2_k127_4017588_1 FtsX-like permease family K02004 - - 2.894e-320 998.0
TH2_k127_4017588_10 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 415.0
TH2_k127_4017588_11 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 403.0
TH2_k127_4017588_12 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 372.0
TH2_k127_4017588_13 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 368.0
TH2_k127_4017588_14 S1 domain K00243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 344.0
TH2_k127_4017588_15 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 297.0
TH2_k127_4017588_16 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 285.0
TH2_k127_4017588_17 CO dehydrogenase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002248 284.0
TH2_k127_4017588_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001659 276.0
TH2_k127_4017588_19 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000007328 263.0
TH2_k127_4017588_2 NADH dehydrogenase - - - 1.63e-224 711.0
TH2_k127_4017588_20 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008934 239.0
TH2_k127_4017588_21 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000001792 192.0
TH2_k127_4017588_22 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000005226 184.0
TH2_k127_4017588_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.00000000000000000000000000000000000000000000000193 179.0
TH2_k127_4017588_24 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000001151 174.0
TH2_k127_4017588_25 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000001481 167.0
TH2_k127_4017588_26 ferredoxin-thioredoxin reductase activity - - - 0.000000000000000000000000000000000000000309 151.0
TH2_k127_4017588_27 protocatechuate 3,4-dioxygenase - - - 0.0000000000000000000000000000000000000008321 152.0
TH2_k127_4017588_28 HNH nucleases - - - 0.00000000000000000000000000000000000001881 146.0
TH2_k127_4017588_29 - - - - 0.00000000000000000000000000000000003706 142.0
TH2_k127_4017588_3 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 1.056e-213 684.0
TH2_k127_4017588_30 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000004146 139.0
TH2_k127_4017588_31 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000001814 134.0
TH2_k127_4017588_32 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000001819 138.0
TH2_k127_4017588_33 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000000000004846 127.0
TH2_k127_4017588_34 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000001646 124.0
TH2_k127_4017588_35 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.000000000000000000004852 97.0
TH2_k127_4017588_37 Peptidoglycan-binding LysM - - - 0.0000000000000615 75.0
TH2_k127_4017588_38 - - - - 0.000000000002306 68.0
TH2_k127_4017588_39 - - - - 0.00000000008016 66.0
TH2_k127_4017588_4 Ftsk_gamma K03466 - - 2.404e-199 644.0
TH2_k127_4017588_40 Tetratricopeptide repeat - - - 0.0001422 53.0
TH2_k127_4017588_5 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 5.13e-199 629.0
TH2_k127_4017588_6 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 6.28e-198 631.0
TH2_k127_4017588_7 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 502.0
TH2_k127_4017588_8 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 444.0
TH2_k127_4017588_9 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 420.0
TH2_k127_40212_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 550.0
TH2_k127_40212_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 366.0
TH2_k127_40212_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000003839 229.0
TH2_k127_40212_3 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000001141 223.0
TH2_k127_40212_4 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000000000000000006725 153.0
TH2_k127_40212_5 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000003879 137.0
TH2_k127_40212_6 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000002263 132.0
TH2_k127_4045980_0 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000001474 215.0
TH2_k127_4045980_1 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000009516 214.0
TH2_k127_4045980_2 virion core protein, lumpy skin disease virus - - - 0.0000000000000000000000000000000000000000000000000000000001366 210.0
TH2_k127_4045980_3 ABC transporter K02065 - - 0.00000000000000000000000000121 116.0
TH2_k127_4045980_4 phosphorelay signal transduction system - - - 0.0000000000000000000005242 99.0
TH2_k127_419350_0 ABC transporter K15738 - - 1.273e-230 730.0
TH2_k127_419350_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 606.0
TH2_k127_419350_2 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005942 484.0
TH2_k127_419350_3 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 338.0
TH2_k127_419350_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.00000000000000000000000000000000000000000000000000000007432 205.0
TH2_k127_419350_5 Cold shock K03704 - - 0.00000000000000000000000001678 109.0
TH2_k127_419350_6 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.0000000000000000003956 99.0
TH2_k127_419350_7 - - - - 0.000000000134 66.0
TH2_k127_43814_0 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 342.0
TH2_k127_43814_1 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 347.0
TH2_k127_43814_10 DEAD-like helicases superfamily K07012 - - 0.00000000001533 72.0
TH2_k127_43814_2 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 324.0
TH2_k127_43814_3 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 289.0
TH2_k127_43814_4 PFAM ABC transporter related K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002953 277.0
TH2_k127_43814_5 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000001157 199.0
TH2_k127_43814_6 Belongs to the Fur family K02076,K03711 GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000038 176.0
TH2_k127_43814_7 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000002953 125.0
TH2_k127_43814_8 CRISPR-associated helicase, Cas3 K07012 - - 0.0000000000000000000000002177 108.0
TH2_k127_43814_9 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.00000000000000000006798 91.0
TH2_k127_4403778_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000911 308.0
TH2_k127_4403778_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 286.0
TH2_k127_4403778_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000001085 175.0
TH2_k127_4403778_3 Nitroreductase family - - - 0.00000000000000000000000000000000001392 137.0
TH2_k127_4403778_4 PFAM PHP domain - - - 0.00000000000000000000000000000000001447 143.0
TH2_k127_4474473_0 Histidine kinase K02668,K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000001196 220.0
TH2_k127_4474473_1 methyltransferase - - - 0.00000000007233 73.0
TH2_k127_4490029_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.752e-221 693.0
TH2_k127_4490029_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 605.0
TH2_k127_4490029_10 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 329.0
TH2_k127_4490029_11 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 316.0
TH2_k127_4490029_12 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 309.0
TH2_k127_4490029_13 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 296.0
TH2_k127_4490029_14 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 287.0
TH2_k127_4490029_15 HEAT repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001179 281.0
TH2_k127_4490029_16 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001098 256.0
TH2_k127_4490029_17 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000002753 248.0
TH2_k127_4490029_18 prephenate dehydrogenase K00220 - 1.3.1.12,1.3.1.43 0.000000000000000000000000000000000000000000000000000000000000000009302 234.0
TH2_k127_4490029_19 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000002205 245.0
TH2_k127_4490029_2 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 510.0
TH2_k127_4490029_20 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000004906 206.0
TH2_k127_4490029_21 - - - - 0.0000000000000000000000000000000000000000000000002426 185.0
TH2_k127_4490029_22 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000001815 164.0
TH2_k127_4490029_23 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000003298 143.0
TH2_k127_4490029_24 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000006907 126.0
TH2_k127_4490029_25 PFAM RNA recognition motif - - - 0.000000000000000000000000009989 113.0
TH2_k127_4490029_26 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000007049 106.0
TH2_k127_4490029_27 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000004315 81.0
TH2_k127_4490029_28 - - - - 0.00000000000002372 81.0
TH2_k127_4490029_29 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000003877 74.0
TH2_k127_4490029_3 large subunit K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 498.0
TH2_k127_4490029_30 aspartic-type endopeptidase activity K06985 - - 0.000001637 59.0
TH2_k127_4490029_4 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 478.0
TH2_k127_4490029_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 473.0
TH2_k127_4490029_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 441.0
TH2_k127_4490029_7 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006891 427.0
TH2_k127_4490029_8 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 413.0
TH2_k127_4490029_9 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 357.0
TH2_k127_4491528_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 9.783e-238 743.0
TH2_k127_4491528_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.938e-229 726.0
TH2_k127_4491528_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.665e-224 705.0
TH2_k127_4491528_3 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 589.0
TH2_k127_4491528_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 461.0
TH2_k127_4491528_5 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 319.0
TH2_k127_4491528_6 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000002563 188.0
TH2_k127_4491528_7 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000001009 109.0
TH2_k127_4511721_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 409.0
TH2_k127_4511721_1 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000003023 151.0
TH2_k127_4511721_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000007006 115.0
TH2_k127_4511721_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000002679 81.0
TH2_k127_4516684_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008538 501.0
TH2_k127_4516684_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 336.0
TH2_k127_4516684_2 sulfur carrier activity - - - 0.0000000000000000000000000000000000000000000000001835 181.0
TH2_k127_4516684_3 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000000005728 121.0
TH2_k127_4519753_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 467.0
TH2_k127_4519753_1 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 383.0
TH2_k127_4519753_2 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000009068 179.0
TH2_k127_4519753_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000008899 171.0
TH2_k127_4519753_4 PFAM ferredoxin-dependent glutamate synthase - - - 0.000000000002199 67.0
TH2_k127_4527018_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 586.0
TH2_k127_4527018_1 transferase activity, transferring glycosyl groups K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 318.0
TH2_k127_4527018_2 biosynthesis glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 297.0
TH2_k127_4527018_3 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000006611 179.0
TH2_k127_4527018_4 Ribonuclease R winged-helix domain protein K09720 - - 0.00000000000000000000002622 102.0
TH2_k127_455320_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1491.0
TH2_k127_455320_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 9.532e-264 830.0
TH2_k127_455320_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 306.0
TH2_k127_455320_3 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003019 244.0
TH2_k127_455320_4 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000005335 211.0
TH2_k127_455320_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000003725 202.0
TH2_k127_455320_6 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000442 156.0
TH2_k127_455320_7 cytochrome complex assembly - - - 0.0000000000000000000000001047 107.0
TH2_k127_455320_8 Belongs to the N-Me-Phe pilin family K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000004239 52.0
TH2_k127_4574689_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847 - 5.4.99.2 0.0 1153.0
TH2_k127_4574689_1 C-terminal, D2-small domain, of ClpB protein K03694 - - 2.492e-284 891.0
TH2_k127_4574689_10 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001312 241.0
TH2_k127_4574689_11 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000001592 204.0
TH2_k127_4574689_12 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000002755 195.0
TH2_k127_4574689_13 Transcriptional regulator - - - 0.00000000000000000000000000000000000000123 152.0
TH2_k127_4574689_14 - - - - 0.000000000000000000000000000000000000002932 167.0
TH2_k127_4574689_15 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000000000000001498 150.0
TH2_k127_4574689_16 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000006972 121.0
TH2_k127_4574689_17 Sulfurtransferase TusA - - - 0.00000000000000000000000002303 109.0
TH2_k127_4574689_18 - - - - 0.00004313 48.0
TH2_k127_4574689_2 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 487.0
TH2_k127_4574689_3 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 409.0
TH2_k127_4574689_4 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 399.0
TH2_k127_4574689_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 410.0
TH2_k127_4574689_6 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 362.0
TH2_k127_4574689_7 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 284.0
TH2_k127_4574689_8 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006777 295.0
TH2_k127_4574689_9 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000003416 245.0
TH2_k127_4580184_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 351.0
TH2_k127_4580184_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000009344 156.0
TH2_k127_466272_0 PFAM HhH-GPD family protein K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 298.0
TH2_k127_466272_1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000000000000001189 148.0
TH2_k127_466272_2 - - - - 0.000000000000000000000000000000000003001 139.0
TH2_k127_466272_3 B12 binding domain K04034 - 1.21.98.3 0.000000000000000000004658 97.0
TH2_k127_466272_4 bacterial (prokaryotic) histone like domain K03530 - - 0.0008282 42.0
TH2_k127_4663927_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 6.118e-278 878.0
TH2_k127_4663927_1 Glycosyl hydrolase family 57 - - - 2.243e-224 714.0
TH2_k127_4663927_10 cell cycle K05589,K12065,K13052 - - 0.00000000000001189 77.0
TH2_k127_4663927_11 Pfam SNARE associated Golgi protein - - - 0.0000000000004701 70.0
TH2_k127_4663927_2 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 462.0
TH2_k127_4663927_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 421.0
TH2_k127_4663927_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 384.0
TH2_k127_4663927_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000001313 163.0
TH2_k127_4663927_6 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000001609 153.0
TH2_k127_4663927_7 - - - - 0.00000000000000000000002187 114.0
TH2_k127_4663927_8 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000004599 96.0
TH2_k127_4663927_9 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000008713 87.0
TH2_k127_4674105_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1296.0
TH2_k127_4674105_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1013.0
TH2_k127_4674105_10 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000001134 210.0
TH2_k127_4674105_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000003204 187.0
TH2_k127_4674105_12 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000005153 181.0
TH2_k127_4674105_13 metalloendopeptidase activity K03799 - - 0.00000000000000000000000000000000000000001377 170.0
TH2_k127_4674105_14 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000004296 147.0
TH2_k127_4674105_15 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000000000000000000000000000001874 136.0
TH2_k127_4674105_16 peroxiredoxin activity - - - 0.000000000000000000000000000004374 125.0
TH2_k127_4674105_17 PFAM amidohydrolase - - - 0.000000000000000000000000002253 124.0
TH2_k127_4674105_18 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000007049 106.0
TH2_k127_4674105_19 PFAM Rubredoxin-type Fe(Cys)4 protein K05297 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0017144,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114,GO:0072592 1.18.1.1 0.0000000000000000000001197 97.0
TH2_k127_4674105_2 Molecular chaperone. Has ATPase activity K04079 - - 2.601e-286 891.0
TH2_k127_4674105_20 NusG domain II K00805 - 2.5.1.30 0.0000000000000000004866 91.0
TH2_k127_4674105_21 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000001013 87.0
TH2_k127_4674105_22 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000003049 72.0
TH2_k127_4674105_23 - - - - 0.0000000000004809 71.0
TH2_k127_4674105_24 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000162 69.0
TH2_k127_4674105_25 Glutaredoxin - - - 0.000001627 52.0
TH2_k127_4674105_26 PFAM Rhodanese domain protein - - - 0.000002092 49.0
TH2_k127_4674105_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 369.0
TH2_k127_4674105_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 362.0
TH2_k127_4674105_5 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 340.0
TH2_k127_4674105_6 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 345.0
TH2_k127_4674105_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 290.0
TH2_k127_4674105_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000002819 259.0
TH2_k127_4674105_9 LysM domain K01449,K19223 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000001164 244.0
TH2_k127_468518_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1086.0
TH2_k127_468518_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1085.0
TH2_k127_468518_10 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 348.0
TH2_k127_468518_11 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 353.0
TH2_k127_468518_12 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 353.0
TH2_k127_468518_13 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 310.0
TH2_k127_468518_14 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 314.0
TH2_k127_468518_15 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 302.0
TH2_k127_468518_16 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 293.0
TH2_k127_468518_17 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000132 274.0
TH2_k127_468518_18 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001877 273.0
TH2_k127_468518_19 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000009122 267.0
TH2_k127_468518_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 589.0
TH2_k127_468518_20 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004784 265.0
TH2_k127_468518_21 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000003322 243.0
TH2_k127_468518_22 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000004171 235.0
TH2_k127_468518_23 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000007594 218.0
TH2_k127_468518_24 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000006917 204.0
TH2_k127_468518_25 Hit family K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000002311 202.0
TH2_k127_468518_26 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000002361 204.0
TH2_k127_468518_27 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000001941 214.0
TH2_k127_468518_28 - - - - 0.000000000000000000000000000000000000000000000000003467 205.0
TH2_k127_468518_29 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000001354 195.0
TH2_k127_468518_3 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 501.0
TH2_k127_468518_31 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000000000000000000000002097 188.0
TH2_k127_468518_32 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000002059 179.0
TH2_k127_468518_33 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000001083 167.0
TH2_k127_468518_34 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000928 168.0
TH2_k127_468518_35 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000002447 160.0
TH2_k127_468518_36 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000005317 149.0
TH2_k127_468518_37 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000003253 149.0
TH2_k127_468518_38 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000008512 149.0
TH2_k127_468518_39 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000258 151.0
TH2_k127_468518_4 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 475.0
TH2_k127_468518_40 Thioredoxin-like - - - 0.00000000000000000000000000000000002143 140.0
TH2_k127_468518_41 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000000001328 124.0
TH2_k127_468518_42 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000002233 126.0
TH2_k127_468518_43 Ribosomal protein S16 K02959 - - 0.000000000000000000000000000815 114.0
TH2_k127_468518_44 Hydrolase, P-loop family K06925 - - 0.000000000000000000000000001834 116.0
TH2_k127_468518_45 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000004887 113.0
TH2_k127_468518_46 peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.00000000000000000000000001096 121.0
TH2_k127_468518_47 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000002437 108.0
TH2_k127_468518_48 - - - - 0.00000000000000000000000459 112.0
TH2_k127_468518_49 iron-sulfur cluster assembly - - - 0.0000000000000000000001054 99.0
TH2_k127_468518_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 455.0
TH2_k127_468518_50 protein secretion K03116,K03117 - - 0.0000000000000474 75.0
TH2_k127_468518_52 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16783,K16785 - - 0.00000000001153 73.0
TH2_k127_468518_53 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000858 63.0
TH2_k127_468518_54 LysM domain - - - 0.000000527 62.0
TH2_k127_468518_55 SurA N-terminal domain K03771 - 5.2.1.8 0.0001773 55.0
TH2_k127_468518_56 - - - - 0.0004566 43.0
TH2_k127_468518_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 415.0
TH2_k127_468518_7 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 396.0
TH2_k127_468518_8 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 398.0
TH2_k127_468518_9 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 370.0
TH2_k127_4688698_0 COG0058 Glucan phosphorylase - - - 3.248e-250 781.0
TH2_k127_4688698_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000001353 113.0
TH2_k127_4688698_2 exodeoxyribonuclease I activity - - - 0.0000000007582 64.0
TH2_k127_4688698_3 Early endosome antigen 1 K12478 GO:0003674,GO:0005488,GO:0005515,GO:0005516,GO:0005543,GO:0005545,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005829,GO:0005886,GO:0005969,GO:0006810,GO:0006897,GO:0006906,GO:0006996,GO:0008150,GO:0008270,GO:0008289,GO:0009987,GO:0010008,GO:0012505,GO:0016020,GO:0016032,GO:0016043,GO:0016050,GO:0016189,GO:0016192,GO:0016197,GO:0016482,GO:0019058,GO:0019079,GO:0019897,GO:0019898,GO:0030139,GO:0030424,GO:0030742,GO:0031090,GO:0031410,GO:0031901,GO:0031982,GO:0032266,GO:0032991,GO:0033267,GO:0035091,GO:0039694,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0044308,GO:0044309,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045022,GO:0046872,GO:0046907,GO:0046914,GO:0046983,GO:0048284,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0055037,GO:0061024,GO:0061025,GO:0071840,GO:0071944,GO:0090174,GO:0097458,GO:0097708,GO:0098588,GO:0098657,GO:0098805,GO:0098927,GO:0099003,GO:0099504,GO:0099532,GO:0120025,GO:0120038,GO:1901981,GO:1902494,GO:1990234 - 0.00001581 59.0
TH2_k127_470146_0 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 424.0
TH2_k127_470146_1 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 359.0
TH2_k127_470146_2 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 317.0
TH2_k127_470146_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009379 284.0
TH2_k127_470146_4 TIGRFAM iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000002025 163.0
TH2_k127_470146_5 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000103 151.0
TH2_k127_470146_6 PFAM response regulator receiver - - - 0.00005706 49.0
TH2_k127_4718815_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.708e-288 901.0
TH2_k127_4718815_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 581.0
TH2_k127_4718815_10 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07478 - - 0.00000000000000000000000000000000000000000000000000000000008043 209.0
TH2_k127_4718815_11 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000297 205.0
TH2_k127_4718815_13 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000009342 184.0
TH2_k127_4718815_14 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000005639 173.0
TH2_k127_4718815_15 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.0000000000000000000000000000000000000000000003237 172.0
TH2_k127_4718815_16 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000025 168.0
TH2_k127_4718815_17 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.0000000000000000000000000000000000000000005136 160.0
TH2_k127_4718815_18 - - - - 0.00000000000000000000000000000000000003905 153.0
TH2_k127_4718815_19 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000004194 134.0
TH2_k127_4718815_2 metal ion transmembrane transporter activity K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 560.0
TH2_k127_4718815_20 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000000000000000000000000574 117.0
TH2_k127_4718815_21 Protein of unknown function DUF134 - - - 0.000000000000000000000000004667 113.0
TH2_k127_4718815_22 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000001856 112.0
TH2_k127_4718815_23 PFAM DsrE DsrF-like family - - - 0.0000000001461 66.0
TH2_k127_4718815_24 Glutamine amidotransferase class-I - - - 0.0000000001753 64.0
TH2_k127_4718815_25 electron transfer activity K05337,K17247 - - 0.0000005097 53.0
TH2_k127_4718815_3 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 568.0
TH2_k127_4718815_4 GTP-binding GTPase Middle Region K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 522.0
TH2_k127_4718815_5 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 465.0
TH2_k127_4718815_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 457.0
TH2_k127_4718815_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 423.0
TH2_k127_4718815_8 Cache_2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 411.0
TH2_k127_4718815_9 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003037 255.0
TH2_k127_4735458_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1092.0
TH2_k127_4735458_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 7.901e-315 988.0
TH2_k127_4735458_10 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 464.0
TH2_k127_4735458_11 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 342.0
TH2_k127_4735458_12 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 348.0
TH2_k127_4735458_13 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 313.0
TH2_k127_4735458_14 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 299.0
TH2_k127_4735458_15 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 290.0
TH2_k127_4735458_16 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002141 242.0
TH2_k127_4735458_17 (Rhomboid) family K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000152 236.0
TH2_k127_4735458_18 PHP-associated K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000004504 229.0
TH2_k127_4735458_19 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000001762 230.0
TH2_k127_4735458_2 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 1.119e-270 844.0
TH2_k127_4735458_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000003529 207.0
TH2_k127_4735458_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001267 199.0
TH2_k127_4735458_22 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000001522 198.0
TH2_k127_4735458_23 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000000000000009464 187.0
TH2_k127_4735458_24 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000001367 194.0
TH2_k127_4735458_25 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000002064 184.0
TH2_k127_4735458_26 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.00000000000000000000000000000000000000000000000005913 190.0
TH2_k127_4735458_27 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000005297 158.0
TH2_k127_4735458_28 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.000000000000000000000000000000000000004269 151.0
TH2_k127_4735458_29 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000001659 142.0
TH2_k127_4735458_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.063e-268 835.0
TH2_k127_4735458_30 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000000000302 145.0
TH2_k127_4735458_31 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000008165 140.0
TH2_k127_4735458_32 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000005479 132.0
TH2_k127_4735458_33 DRTGG domain - - - 0.00000000000000000000000000000001312 129.0
TH2_k127_4735458_34 phosphorelay signal transduction system K02437 - - 0.00000000000000000000000000001102 128.0
TH2_k127_4735458_35 DRTGG domain - - - 0.000000000000000000000003315 109.0
TH2_k127_4735458_36 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000002873 79.0
TH2_k127_4735458_37 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000001178 71.0
TH2_k127_4735458_38 Belongs to the 'phage' integrase family - - - 0.00000000003497 68.0
TH2_k127_4735458_39 protein transport across the cell outer membrane K02246,K02457,K02459,K02672,K08084 - - 0.00000000379 66.0
TH2_k127_4735458_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.839e-265 833.0
TH2_k127_4735458_40 Pfam:N_methyl_2 K02459 - - 0.000001849 57.0
TH2_k127_4735458_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 566.0
TH2_k127_4735458_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 562.0
TH2_k127_4735458_7 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 555.0
TH2_k127_4735458_8 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 533.0
TH2_k127_4735458_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 513.0
TH2_k127_4747815_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1161.0
TH2_k127_4747815_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 544.0
TH2_k127_4747815_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000009443 231.0
TH2_k127_4747815_11 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000001377 157.0
TH2_k127_4747815_12 GYD domain - - - 0.000000000000000000000000000000000296 134.0
TH2_k127_4747815_13 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000006598 106.0
TH2_k127_4747815_14 sulfur carrier activity K04085 - - 0.0000000000000000000123 94.0
TH2_k127_4747815_15 Belongs to the MEMO1 family K06990 - - 0.0000000000000000004713 88.0
TH2_k127_4747815_2 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 546.0
TH2_k127_4747815_3 PFAM RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 447.0
TH2_k127_4747815_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 379.0
TH2_k127_4747815_5 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 366.0
TH2_k127_4747815_6 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 360.0
TH2_k127_4747815_7 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 348.0
TH2_k127_4747815_8 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 326.0
TH2_k127_4747815_9 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 294.0
TH2_k127_4754951_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 556.0
TH2_k127_4754951_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 535.0
TH2_k127_4754951_2 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 447.0
TH2_k127_4754951_3 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 347.0
TH2_k127_4754951_4 metal-dependent phosphohydrolase HD sub K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 344.0
TH2_k127_4754951_5 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.0000000000000000000000000000003936 122.0
TH2_k127_4784165_0 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 445.0
TH2_k127_4784165_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 421.0
TH2_k127_4784165_2 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 267.0
TH2_k127_4784165_3 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000000000000000000005607 206.0
TH2_k127_4784165_4 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000001458 174.0
TH2_k127_4784165_5 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000001148 141.0
TH2_k127_4784165_6 Protein required for attachment to host cells - - - 0.0000000000000000000000000000000195 131.0
TH2_k127_4793895_0 L-glutamate biosynthetic process - - - 2.555e-194 610.0
TH2_k127_4793895_1 Phage tail sheath C-terminal domain K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 517.0
TH2_k127_4793895_2 Calcineurin-like phosphoesterase superfamily domain K03269 - 3.6.1.54 0.000000000000000000000000000000003367 136.0
TH2_k127_4793895_3 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.00000000000000003433 86.0
TH2_k127_4846659_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 550.0
TH2_k127_4846659_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 394.0
TH2_k127_4846659_10 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000001238 214.0
TH2_k127_4846659_11 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000002499 216.0
TH2_k127_4846659_12 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000003524 147.0
TH2_k127_4846659_13 RNA-binding protein containing a PIN domain K06962 - - 0.00000000000000000000000000000000005152 140.0
TH2_k127_4846659_14 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000001612 135.0
TH2_k127_4846659_15 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000007002 122.0
TH2_k127_4846659_16 DUF167 - - - 0.00000000000005958 74.0
TH2_k127_4846659_17 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.000000000003531 72.0
TH2_k127_4846659_18 - - - - 0.0000003102 57.0
TH2_k127_4846659_19 - - - - 0.0008038 46.0
TH2_k127_4846659_2 Transcriptional regulator K11921,K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 380.0
TH2_k127_4846659_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002835 279.0
TH2_k127_4846659_4 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001259 286.0
TH2_k127_4846659_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001916 260.0
TH2_k127_4846659_6 PFAM response regulator receiver K02483,K18344 - - 0.000000000000000000000000000000000000000000000000000000000000000000002215 242.0
TH2_k127_4846659_7 phosphatidate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003971 244.0
TH2_k127_4846659_8 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000001307 243.0
TH2_k127_4853023_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 6.24e-283 885.0
TH2_k127_4853023_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.255e-278 867.0
TH2_k127_4853023_10 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 366.0
TH2_k127_4853023_11 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 363.0
TH2_k127_4853023_12 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 324.0
TH2_k127_4853023_13 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 329.0
TH2_k127_4853023_14 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 319.0
TH2_k127_4853023_15 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 311.0
TH2_k127_4853023_16 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 295.0
TH2_k127_4853023_17 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 295.0
TH2_k127_4853023_18 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001261 278.0
TH2_k127_4853023_19 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000004015 267.0
TH2_k127_4853023_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 607.0
TH2_k127_4853023_20 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004477 268.0
TH2_k127_4853023_21 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000004531 248.0
TH2_k127_4853023_22 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003616 253.0
TH2_k127_4853023_23 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000001363 226.0
TH2_k127_4853023_24 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000001558 219.0
TH2_k127_4853023_25 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000001225 210.0
TH2_k127_4853023_26 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000001159 211.0
TH2_k127_4853023_27 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000000000000000000000000000000000000000000000000003346 210.0
TH2_k127_4853023_28 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000008951 199.0
TH2_k127_4853023_29 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000007603 193.0
TH2_k127_4853023_3 B3/4 domain K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 572.0
TH2_k127_4853023_30 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000004139 196.0
TH2_k127_4853023_31 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000364 187.0
TH2_k127_4853023_32 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000216 181.0
TH2_k127_4853023_33 - - - - 0.0000000000000000000000000000000000000000000009377 175.0
TH2_k127_4853023_34 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000002153 144.0
TH2_k127_4853023_35 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000005425 129.0
TH2_k127_4853023_36 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000005962 134.0
TH2_k127_4853023_37 OstA-like protein K09774 - - 0.00000000000000000000000000000001414 132.0
TH2_k127_4853023_38 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.0000000000000000000000000000001667 130.0
TH2_k127_4853023_39 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000007928 117.0
TH2_k127_4853023_4 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 523.0
TH2_k127_4853023_40 JAB/MPN domain - - - 0.0000000000000000000000000002316 120.0
TH2_k127_4853023_41 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001129 93.0
TH2_k127_4853023_42 EamA-like transporter family - - - 0.0000000000000000000222 101.0
TH2_k127_4853023_43 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000008654 88.0
TH2_k127_4853023_44 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000003408 93.0
TH2_k127_4853023_45 - - - - 0.0000000000000000114 85.0
TH2_k127_4853023_46 PFAM Uncharacterised protein family UPF0150 - - - 0.000000002291 59.0
TH2_k127_4853023_47 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000002161 57.0
TH2_k127_4853023_48 - - - - 0.00001094 49.0
TH2_k127_4853023_49 Lipopolysaccharide-assembly, LptC-related - - - 0.00001999 53.0
TH2_k127_4853023_5 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 492.0
TH2_k127_4853023_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 477.0
TH2_k127_4853023_7 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 452.0
TH2_k127_4853023_8 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 445.0
TH2_k127_4853023_9 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 419.0
TH2_k127_486140_0 COG1194 A G-specific DNA glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 301.0
TH2_k127_486140_1 PFAM ATP adenylyltransferase K00988 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 298.0
TH2_k127_486140_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000001231 177.0
TH2_k127_4879632_0 Telomere recombination K04656 - - 2.555e-242 773.0
TH2_k127_4879632_1 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 469.0
TH2_k127_4879632_2 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 374.0
TH2_k127_4879632_3 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001366 253.0
TH2_k127_4886674_0 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 431.0
TH2_k127_4886674_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000007963 83.0
TH2_k127_4894282_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.594e-278 876.0
TH2_k127_4894282_1 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 9.062e-275 870.0
TH2_k127_4894282_10 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 382.0
TH2_k127_4894282_11 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006771 336.0
TH2_k127_4894282_12 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 327.0
TH2_k127_4894282_13 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 332.0
TH2_k127_4894282_14 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000493 289.0
TH2_k127_4894282_15 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002127 280.0
TH2_k127_4894282_16 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000008282 259.0
TH2_k127_4894282_17 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000257 244.0
TH2_k127_4894282_18 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000002638 243.0
TH2_k127_4894282_19 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000001159 153.0
TH2_k127_4894282_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.88e-258 823.0
TH2_k127_4894282_20 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000002291 139.0
TH2_k127_4894282_21 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000002699 100.0
TH2_k127_4894282_22 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000007383 90.0
TH2_k127_4894282_23 - - - - 0.000000000000000002882 90.0
TH2_k127_4894282_24 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 K09667 GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252 2.4.1.255 0.000000000000004109 83.0
TH2_k127_4894282_25 Pilus assembly protein, PilP K02665 - - 0.00000000000005797 78.0
TH2_k127_4894282_26 COG3167 Tfp pilus assembly protein PilO K02664 - - 0.000000000005245 74.0
TH2_k127_4894282_27 Domain of unknown function (DUF4912) K09942 - - 0.00000000001313 76.0
TH2_k127_4894282_28 Protein of unknown function (DUF721) - - - 0.00006615 51.0
TH2_k127_4894282_3 Protein of unknown function, DUF255 K06888 - - 7.95e-241 758.0
TH2_k127_4894282_4 Transport of potassium into the cell K03549 - - 3.081e-239 753.0
TH2_k127_4894282_5 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 3.226e-236 744.0
TH2_k127_4894282_6 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 578.0
TH2_k127_4894282_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 465.0
TH2_k127_4894282_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 422.0
TH2_k127_4894282_9 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 415.0
TH2_k127_4897077_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 517.0
TH2_k127_4897077_1 - - - - 0.000000000000000000000000000000000000002059 154.0
TH2_k127_4897077_2 PFAM transposase IS116 IS110 IS902 - - - 0.000000000000000000000000000003315 127.0
TH2_k127_4951146_0 COG0463 Glycosyltransferases involved in cell wall biogenesis K13002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003872 263.0
TH2_k127_4951146_2 Domain of unknown function (DUF4143) K07133 - - 0.0000000715 55.0
TH2_k127_4973789_0 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 328.0
TH2_k127_4973789_1 Transcriptional regulator - - - 0.00000000000000000000000000000764 121.0
TH2_k127_4973789_2 addiction module killer protein - - - 0.00000000000000000000000000007826 117.0
TH2_k127_4973789_3 NTPase K06928 - 3.6.1.15 0.00002242 48.0
TH2_k127_4973789_4 domain protein - - - 0.0005006 48.0
TH2_k127_5002685_0 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 465.0
TH2_k127_5002685_1 PFAM Response regulator receiver domain - - - 0.000000000000000000003713 98.0
TH2_k127_5048640_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 1.877e-204 641.0
TH2_k127_5048640_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.38e-200 634.0
TH2_k127_5048640_10 SMART helix-turn-helix domain protein K15539 - - 0.00000000003305 73.0
TH2_k127_5048640_11 DnaJ-class molecular chaperone with C-terminal Zn finger domain - - - 0.00000000976 68.0
TH2_k127_5048640_2 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 541.0
TH2_k127_5048640_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 489.0
TH2_k127_5048640_4 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 386.0
TH2_k127_5048640_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 327.0
TH2_k127_5048640_6 Histidine kinase HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000000003467 238.0
TH2_k127_5048640_7 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000004505 210.0
TH2_k127_5048640_8 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000007044 181.0
TH2_k127_5048640_9 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000003052 79.0
TH2_k127_5079988_0 lipopolysaccharide transport K22110 - - 0.0 1146.0
TH2_k127_5079988_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 519.0
TH2_k127_5079988_10 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001795 210.0
TH2_k127_5079988_11 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000002529 212.0
TH2_k127_5079988_12 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000002644 178.0
TH2_k127_5079988_13 Uncharacterized protein conserved in bacteria (DUF2064) K09931,K20742 - 3.4.14.13 0.00000000000000000000000000000000000000002743 160.0
TH2_k127_5079988_14 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000002413 138.0
TH2_k127_5079988_15 cell redox homeostasis - - - 0.000000000000000000000000000007043 119.0
TH2_k127_5079988_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 423.0
TH2_k127_5079988_3 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 409.0
TH2_k127_5079988_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 403.0
TH2_k127_5079988_5 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 394.0
TH2_k127_5079988_6 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 320.0
TH2_k127_5079988_7 PFAM Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 299.0
TH2_k127_5079988_8 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003643 279.0
TH2_k127_5079988_9 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003022 263.0
TH2_k127_5201007_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 601.0
TH2_k127_5201007_1 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 499.0
TH2_k127_5201007_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 396.0
TH2_k127_5201007_3 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 344.0
TH2_k127_5201007_4 pyridoxamine 5-phosphate oxidase-related K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008975 245.0
TH2_k127_5201007_5 NAD(P)H dehydrogenase K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000003397 229.0
TH2_k127_5201007_6 Mate efflux family protein - - - 0.0005693 43.0
TH2_k127_5250208_0 Cytochrome c bacterial - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 516.0
TH2_k127_5250208_1 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 362.0
TH2_k127_5250208_2 cyclic nucleotide binding K04739,K10914 - - 0.000000000001514 78.0
TH2_k127_5250208_3 Transcriptional regulator - - - 0.000000000006979 68.0
TH2_k127_5270119_0 Cytochrome c554 and c-prime - - - 5.489e-247 770.0
TH2_k127_5270119_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 468.0
TH2_k127_5270119_2 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000299 258.0
TH2_k127_5270119_3 Pfam:TPM K08988 - - 0.00000000000000000000000000000000000000000000000000000007926 205.0
TH2_k127_5270119_4 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000006184 134.0
TH2_k127_5270119_6 - - - - 0.00000000127 63.0
TH2_k127_5309573_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 571.0
TH2_k127_5309573_1 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 478.0
TH2_k127_5309573_2 cytochrome complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000025 211.0
TH2_k127_5349157_0 NADH ubiquinone oxidoreductase K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 2.844e-198 634.0
TH2_k127_5349157_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 587.0
TH2_k127_5349157_2 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 461.0
TH2_k127_5349157_3 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 368.0
TH2_k127_5349157_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000001572 167.0
TH2_k127_5349157_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000001944 125.0
TH2_k127_5349157_6 Cyclic nucleotide-monophosphate binding domain - - - 0.00000565 54.0
TH2_k127_5484688_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 3.795e-237 741.0
TH2_k127_5484688_1 Endoribonuclease that initiates mRNA decay K18682 - - 2.889e-209 662.0
TH2_k127_5484688_2 AAA ATPase, central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 454.0
TH2_k127_5484688_3 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 327.0
TH2_k127_5484688_4 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000004129 175.0
TH2_k127_5484688_5 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 0.0000000000000000000000000000000006521 130.0
TH2_k127_5484688_6 carbon dioxide binding K04653 - - 0.0000000000000000003501 89.0
TH2_k127_5554243_0 chelatase, subunit ChlI K07391 - - 1.015e-209 662.0
TH2_k127_5554243_1 Histidine kinase - - - 1.391e-194 647.0
TH2_k127_5554243_10 heat shock protein binding - - - 0.00000000000000000000000000000000000004448 154.0
TH2_k127_5554243_11 formate dehydrogenase - - - 0.0000000000000000000000000000000005833 142.0
TH2_k127_5554243_12 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000002975 131.0
TH2_k127_5554243_13 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000005215 128.0
TH2_k127_5554243_14 COG0058 Glucan phosphorylase - - - 0.0000000000000000000000006681 105.0
TH2_k127_5554243_2 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 430.0
TH2_k127_5554243_3 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 380.0
TH2_k127_5554243_4 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 292.0
TH2_k127_5554243_5 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002797 259.0
TH2_k127_5554243_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000001153 239.0
TH2_k127_5554243_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000001735 224.0
TH2_k127_5554243_8 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000012 203.0
TH2_k127_5554243_9 heme-binding sites - - - 0.0000000000000000000000000000000000000001963 159.0
TH2_k127_5586774_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 382.0
TH2_k127_5586774_1 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001377 271.0
TH2_k127_5586774_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000006351 205.0
TH2_k127_5586774_3 NmrA-like family - - - 0.0000000000000000000000000000000000000000000008384 173.0
TH2_k127_5586774_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000006054 148.0
TH2_k127_5586774_5 - - - - 0.00000000000000000002298 94.0
TH2_k127_5586774_6 domain protein - - - 0.000001909 56.0
TH2_k127_5610243_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.582e-311 970.0
TH2_k127_5610243_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 8.01e-262 829.0
TH2_k127_5610243_10 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009033 401.0
TH2_k127_5610243_11 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 375.0
TH2_k127_5610243_12 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 361.0
TH2_k127_5610243_13 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 352.0
TH2_k127_5610243_14 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 337.0
TH2_k127_5610243_15 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 334.0
TH2_k127_5610243_16 membrane K09133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 336.0
TH2_k127_5610243_17 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 327.0
TH2_k127_5610243_18 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 320.0
TH2_k127_5610243_19 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 297.0
TH2_k127_5610243_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 601.0
TH2_k127_5610243_20 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 295.0
TH2_k127_5610243_21 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001193 284.0
TH2_k127_5610243_22 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000132 276.0
TH2_k127_5610243_23 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008793 265.0
TH2_k127_5610243_24 ATP cone domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007988 259.0
TH2_k127_5610243_25 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 255.0
TH2_k127_5610243_26 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000006045 246.0
TH2_k127_5610243_27 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000003694 230.0
TH2_k127_5610243_28 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000009572 225.0
TH2_k127_5610243_29 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000002063 226.0
TH2_k127_5610243_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 559.0
TH2_k127_5610243_30 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000000000000000000000414 207.0
TH2_k127_5610243_31 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000005863 206.0
TH2_k127_5610243_32 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000008509 212.0
TH2_k127_5610243_33 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000003228 197.0
TH2_k127_5610243_34 Belongs to the DsbB family K03611 - - 0.000000000000000000000000000000000000000000001846 170.0
TH2_k127_5610243_35 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000002856 159.0
TH2_k127_5610243_36 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000002019 157.0
TH2_k127_5610243_37 NTPase - - - 0.000000000000000000000000000000000000004082 151.0
TH2_k127_5610243_38 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000001373 148.0
TH2_k127_5610243_39 translation release factor activity - - - 0.00000000000000000000000000000000000001571 149.0
TH2_k127_5610243_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 543.0
TH2_k127_5610243_40 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000005881 148.0
TH2_k127_5610243_41 DivIVA protein K04074 - - 0.00000000000000000000002306 105.0
TH2_k127_5610243_42 Domain of unknown function (DUF4388) - - - 0.00000000000000000000003264 114.0
TH2_k127_5610243_43 - - - - 0.00000000000000000003702 99.0
TH2_k127_5610243_44 - - - - 0.000000000000000000238 94.0
TH2_k127_5610243_45 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000001406 84.0
TH2_k127_5610243_46 Uncharacterised protein family (UPF0158) - - - 0.000000000003477 74.0
TH2_k127_5610243_47 DnaJ molecular chaperone homology domain - - - 0.0000000002058 73.0
TH2_k127_5610243_48 TonB C terminal K03832 - - 0.000005196 57.0
TH2_k127_5610243_5 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 506.0
TH2_k127_5610243_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 487.0
TH2_k127_5610243_7 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 460.0
TH2_k127_5610243_8 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 406.0
TH2_k127_5610243_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 396.0
TH2_k127_5624007_0 PFAM MscS Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 381.0
TH2_k127_5624007_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 372.0
TH2_k127_5624007_2 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 364.0
TH2_k127_5624007_3 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000447 297.0
TH2_k127_5624007_4 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K00773,K07319,K11782,K15461 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005869 284.0
TH2_k127_5624007_5 Protein involved in outer membrane biogenesis K07289,K09800 - - 0.00000000000000000000000000000000000000000000005625 195.0
TH2_k127_5624007_6 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000000000001909 171.0
TH2_k127_5625045_0 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 435.0
TH2_k127_5625045_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000001063 243.0
TH2_k127_5625045_2 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000003942 190.0
TH2_k127_5625045_3 - - - - 0.0000000000000000000000000000000000000000000006454 168.0
TH2_k127_5625045_4 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000009182 158.0
TH2_k127_5625045_5 PFAM Transglycosylase-associated protein - - - 0.0000000000000000000000000000000037 129.0
TH2_k127_5625045_6 Peptidoglycan-binding LysM - - - 0.00000000000001318 75.0
TH2_k127_5625045_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0009972 48.0
TH2_k127_5626940_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1153.0
TH2_k127_5626940_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 1.677e-232 728.0
TH2_k127_5626940_10 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001167 271.0
TH2_k127_5626940_11 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000007918 225.0
TH2_k127_5626940_12 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000000000007928 183.0
TH2_k127_5626940_13 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000001018 174.0
TH2_k127_5626940_14 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000004434 155.0
TH2_k127_5626940_15 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000003023 128.0
TH2_k127_5626940_16 HupF/HypC family K04653 - - 0.0000000000000000003501 89.0
TH2_k127_5626940_17 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000206 81.0
TH2_k127_5626940_2 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 535.0
TH2_k127_5626940_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 487.0
TH2_k127_5626940_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 450.0
TH2_k127_5626940_5 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 417.0
TH2_k127_5626940_6 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 392.0
TH2_k127_5626940_7 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 389.0
TH2_k127_5626940_8 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 359.0
TH2_k127_5626940_9 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 302.0
TH2_k127_5632632_0 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 308.0
TH2_k127_5632632_1 anaerobic respiration - - - 0.0000000000000000000000000000002057 134.0
TH2_k127_5635629_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 537.0
TH2_k127_5635629_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 535.0
TH2_k127_5635629_10 Periplasmic or secreted lipoprotein - - - 0.00001821 46.0
TH2_k127_5635629_2 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 290.0
TH2_k127_5635629_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005845 305.0
TH2_k127_5635629_4 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000000000000000008368 181.0
TH2_k127_5635629_5 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000001381 150.0
TH2_k127_5635629_6 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000001167 95.0
TH2_k127_5635629_7 Two component signalling adaptor domain K03408 - - 0.00000000000000000004529 98.0
TH2_k127_5635629_8 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000001966 58.0
TH2_k127_5635629_9 PBP superfamily domain K02040 - - 0.000001952 55.0
TH2_k127_5672238_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 1.156e-267 830.0
TH2_k127_5672238_1 carboxylase K01965,K01968 - 6.4.1.3,6.4.1.4 7.01e-260 816.0
TH2_k127_5672238_10 YtkA-like - - - 0.0000000000000000000000000002861 125.0
TH2_k127_5672238_11 Protein of unknown function (DUF1622) - - - 0.0000000000000000000003238 101.0
TH2_k127_5672238_13 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000001355 68.0
TH2_k127_5672238_15 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.00000001151 66.0
TH2_k127_5672238_17 Putative regulatory protein - - - 0.000001351 52.0
TH2_k127_5672238_2 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 497.0
TH2_k127_5672238_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 399.0
TH2_k127_5672238_4 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 317.0
TH2_k127_5672238_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 304.0
TH2_k127_5672238_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001338 232.0
TH2_k127_5672238_7 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000002351 233.0
TH2_k127_5672238_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000007352 203.0
TH2_k127_5672238_9 GYD domain - - - 0.00000000000000000000000000000000004707 135.0
TH2_k127_5683013_0 Bacterial protein of unknown function (DUF853) K06915 - - 4.017e-216 679.0
TH2_k127_5683013_1 PFAM UvrD REP helicase K03656,K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 601.0
TH2_k127_5683013_10 - - - - 0.0000000000000000000000002799 109.0
TH2_k127_5683013_11 Two component transcriptional regulator, winged helix family K02483,K18344 - - 0.000002392 58.0
TH2_k127_5683013_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 591.0
TH2_k127_5683013_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000269 277.0
TH2_k127_5683013_4 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006579 273.0
TH2_k127_5683013_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006921 266.0
TH2_k127_5683013_6 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000134 210.0
TH2_k127_5683013_7 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000000000000000329 212.0
TH2_k127_5683013_8 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000002608 175.0
TH2_k127_5683013_9 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000663 156.0
TH2_k127_5714390_0 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 9.613e-240 745.0
TH2_k127_5714390_1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain K13747 - 4.1.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 594.0
TH2_k127_5714390_10 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000402 69.0
TH2_k127_5714390_2 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 578.0
TH2_k127_5714390_3 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 563.0
TH2_k127_5714390_4 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 373.0
TH2_k127_5714390_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 323.0
TH2_k127_5714390_6 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000004826 213.0
TH2_k127_5714390_7 PFAM GGDEF domain containing protein K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000002287 188.0
TH2_k127_5714390_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000000000002109 173.0
TH2_k127_5714390_9 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000000003786 166.0
TH2_k127_5720413_0 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 604.0
TH2_k127_5720413_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 424.0
TH2_k127_5720413_2 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 400.0
TH2_k127_5720413_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 316.0
TH2_k127_5720413_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005933 293.0
TH2_k127_5720413_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000881 254.0
TH2_k127_5720413_6 GTP-binding GTPase Middle Region K03665 - - 0.000000000000000000000000000000000000000002492 158.0
TH2_k127_5740757_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 581.0
TH2_k127_5740757_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 358.0
TH2_k127_5759137_0 Sigma-54 interaction domain K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 418.0
TH2_k127_5759137_1 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 379.0
TH2_k127_5759137_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000004451 231.0
TH2_k127_5759137_11 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000004257 219.0
TH2_k127_5759137_12 cobalamin synthesis protein, P47K - - - 0.00000000000000000000000000000000000000000001354 175.0
TH2_k127_5759137_13 Transcriptional regulator K02019,K05772 - - 0.00000000000000000000000000000000000001708 149.0
TH2_k127_5759137_14 Transcription factor zinc-finger K09981 - - 0.000000000000000000000000007666 113.0
TH2_k127_5759137_16 Belongs to the peptidase M48B family K03799 - - 0.0008306 51.0
TH2_k127_5759137_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 295.0
TH2_k127_5759137_3 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 305.0
TH2_k127_5759137_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 304.0
TH2_k127_5759137_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004639 274.0
TH2_k127_5759137_6 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000001596 269.0
TH2_k127_5759137_7 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 257.0
TH2_k127_5759137_8 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000158 235.0
TH2_k127_5759137_9 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000008753 256.0
TH2_k127_5792209_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 484.0
TH2_k127_5792209_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 500.0
TH2_k127_5792209_2 Histidine kinase - - - 0.000000000003997 70.0
TH2_k127_5804983_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 522.0
TH2_k127_5804983_1 PFAM Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 413.0
TH2_k127_5804983_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 358.0
TH2_k127_5804983_3 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 327.0
TH2_k127_5804983_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 308.0
TH2_k127_5804983_5 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002311 255.0
TH2_k127_5804983_6 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000002649 177.0
TH2_k127_5804983_7 MgtC family K07507 - - 0.00000000000000000000000000000000000001233 152.0
TH2_k127_5804983_8 - - - - 0.00000000000000000000008092 101.0
TH2_k127_5804983_9 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 0.0000000001058 63.0
TH2_k127_5848964_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 511.0
TH2_k127_5848964_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 482.0
TH2_k127_5848964_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 378.0
TH2_k127_5872730_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000009402 145.0
TH2_k127_5872730_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000007959 95.0
TH2_k127_5878158_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.456e-207 653.0
TH2_k127_5878158_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 384.0
TH2_k127_5878158_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000007152 214.0
TH2_k127_5878158_11 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000002267 216.0
TH2_k127_5878158_12 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006836 200.0
TH2_k127_5878158_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000434 198.0
TH2_k127_5878158_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000009398 197.0
TH2_k127_5878158_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001416 183.0
TH2_k127_5878158_16 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000003482 179.0
TH2_k127_5878158_17 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000004314 167.0
TH2_k127_5878158_18 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001641 157.0
TH2_k127_5878158_19 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000007011 151.0
TH2_k127_5878158_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 347.0
TH2_k127_5878158_20 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000004098 147.0
TH2_k127_5878158_21 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000003871 134.0
TH2_k127_5878158_22 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000006061 133.0
TH2_k127_5878158_23 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000001655 130.0
TH2_k127_5878158_24 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000006812 107.0
TH2_k127_5878158_25 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000007692 109.0
TH2_k127_5878158_26 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000004445 106.0
TH2_k127_5878158_27 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000003859 79.0
TH2_k127_5878158_28 Ribosomal protein L36 K02919 - - 0.00000000000001418 73.0
TH2_k127_5878158_29 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000001667 73.0
TH2_k127_5878158_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 337.0
TH2_k127_5878158_30 Ribosomal protein L30 K02907 - - 0.0000000001375 63.0
TH2_k127_5878158_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 315.0
TH2_k127_5878158_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001044 277.0
TH2_k127_5878158_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000632 278.0
TH2_k127_5878158_7 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001565 273.0
TH2_k127_5878158_8 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000002526 231.0
TH2_k127_5878158_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000006061 233.0
TH2_k127_5895407_0 - - - - 0.0000000000000000000000000000000000000000000000000000000004822 208.0
TH2_k127_5895407_1 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000003393 197.0
TH2_k127_5895407_2 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000001564 164.0
TH2_k127_5895407_3 - - - - 0.0000000000000000000000000000000003087 135.0
TH2_k127_5895407_4 MOSC domain - - - 0.00000000000000000002752 92.0
TH2_k127_5898798_0 PFAM Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 532.0
TH2_k127_5898798_1 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 533.0
TH2_k127_5898798_2 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 529.0
TH2_k127_5898798_3 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000000000000005234 194.0
TH2_k127_5898798_4 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000002697 169.0
TH2_k127_5898798_5 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000001072 164.0
TH2_k127_5898798_6 regulation of translation K03530 - - 0.0000000000000000000000000000003688 124.0
TH2_k127_5898798_7 - - - - 0.000000000001946 74.0
TH2_k127_5911777_0 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 375.0
TH2_k127_5911777_1 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 364.0
TH2_k127_5911777_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0000000000000000000000000000000000000000000000000003846 187.0
TH2_k127_5911777_3 - K07071 - - 0.000000000000000000000000003222 118.0
TH2_k127_5911777_4 - - - - 0.0000000000001234 73.0
TH2_k127_5911777_5 Belongs to the glycosyl hydrolase 26 family - - - 0.00000000001468 72.0
TH2_k127_5911777_6 Histidine kinase HAMP - - - 0.0000006769 56.0
TH2_k127_5918244_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 473.0
TH2_k127_5918244_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 428.0
TH2_k127_5918244_10 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000002313 67.0
TH2_k127_5918244_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007567 252.0
TH2_k127_5918244_3 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000001395 185.0
TH2_k127_5918244_4 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000003576 158.0
TH2_k127_5918244_5 SMART HNH nuclease K07451 - - 0.0000000000000000000000000000000000000001225 152.0
TH2_k127_5918244_6 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000001148 117.0
TH2_k127_5918244_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000005383 114.0
TH2_k127_5918244_8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000434 109.0
TH2_k127_5918244_9 Protein of unknown function (DUF507) - - - 0.000000000000000000001276 97.0
TH2_k127_5926378_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 337.0
TH2_k127_5926378_1 Polysaccharide biosynthesis/export protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 338.0
TH2_k127_5926378_2 Chain length determinant protein - - - 0.0000000000000000000000000000000000000000000001215 175.0
TH2_k127_5984316_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 310.0
TH2_k127_5984316_1 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000003326 238.0
TH2_k127_5984316_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000005807 168.0
TH2_k127_5984316_3 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 0.000000000000000000000001714 104.0
TH2_k127_5984316_4 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000001449 83.0
TH2_k127_5984837_0 Diguanylate cyclase K21024 - 3.1.4.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 472.0
TH2_k127_5984837_1 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000000000000000000004832 153.0
TH2_k127_599241_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 492.0
TH2_k127_599241_1 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000002592 226.0
TH2_k127_599241_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000003095 84.0
TH2_k127_6030904_0 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000422 267.0
TH2_k127_6030904_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000004658 233.0
TH2_k127_6030904_2 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000008737 180.0
TH2_k127_6030904_3 acetyltransferase - - - 0.0000000000000000000007123 105.0
TH2_k127_6030904_4 PFAM Prokaryotic N-terminal methylation motif K02650 - - 0.000000004354 64.0
TH2_k127_6030904_5 Belongs to the N-Me-Phe pilin family K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000002593 59.0
TH2_k127_6030904_6 Prokaryotic N-terminal methylation motif - - - 0.0000044 55.0
TH2_k127_6078407_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 537.0
TH2_k127_6078407_1 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 373.0
TH2_k127_6078407_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007539 364.0
TH2_k127_6078407_3 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000003823 222.0
TH2_k127_6078407_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000004622 194.0
TH2_k127_6078407_5 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000001899 167.0
TH2_k127_6089333_0 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000001641 201.0
TH2_k127_6089333_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000006108 164.0
TH2_k127_6089333_2 Sulphur transport K07112 - - 0.000000000000000000000000000000000000003238 156.0
TH2_k127_6089333_3 Sulphur transport K07112 - - 0.000000000000000000000000000000000001369 144.0
TH2_k127_6089333_4 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000001252 126.0
TH2_k127_6089333_5 RNase H - - - 0.00000000000000000000000006342 118.0
TH2_k127_6089333_6 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000003316 75.0
TH2_k127_6089333_7 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.0000000000006378 79.0
TH2_k127_6089333_8 Cation efflux family K16264 - - 0.000000000001055 69.0
TH2_k127_60950_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 503.0
TH2_k127_60950_1 PFAM ATPase BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 398.0
TH2_k127_60950_2 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 304.0
TH2_k127_60950_3 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000005661 242.0
TH2_k127_60950_4 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000008734 225.0
TH2_k127_60950_5 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000001466 141.0
TH2_k127_60950_6 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000001217 63.0
TH2_k127_6170704_0 PFAM Metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 409.0
TH2_k127_6170704_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 340.0
TH2_k127_6170704_10 Uncharacterised protein family (UPF0175) - - - 0.00000005025 55.0
TH2_k127_6170704_11 Protein of unknown function (DUF2934) - - - 0.000008247 51.0
TH2_k127_6170704_12 transposase activity - - - 0.0001122 49.0
TH2_k127_6170704_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000005579 231.0
TH2_k127_6170704_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007911 223.0
TH2_k127_6170704_4 Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000000000000000002095 174.0
TH2_k127_6170704_5 PFAM Phage derived protein Gp49-like (DUF891) - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000001002 144.0
TH2_k127_6170704_6 sequence-specific DNA binding - - - 0.0000000000000000000000000000006329 124.0
TH2_k127_6170704_7 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000001487 109.0
TH2_k127_6170704_8 transposase activity - - - 0.00000000003634 68.0
TH2_k127_6170704_9 PFAM Uncharacterised protein family UPF0175 - - - 0.000000003315 59.0
TH2_k127_618752_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.261e-211 665.0
TH2_k127_618752_1 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 404.0
TH2_k127_618752_10 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000006897 173.0
TH2_k127_618752_11 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000009053 155.0
TH2_k127_618752_12 Belongs to the UPF0296 family K09777 - - 0.000000000000000000000000001261 115.0
TH2_k127_618752_13 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000001782 113.0
TH2_k127_618752_14 Tetratricopeptide repeat - - - 0.00000000000000000000009421 111.0
TH2_k127_618752_15 Psort location Cytoplasmic, score - - - 0.00000000000000000142 86.0
TH2_k127_618752_16 Roadblock/LC7 domain - - - 0.000000000000000005823 88.0
TH2_k127_618752_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 381.0
TH2_k127_618752_3 Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid K00627,K05714,K10216,K10222,K10623 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0018771,GO:0019439,GO:0019622,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046164,GO:0046395,GO:0046435,GO:0052823,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 2.3.1.12,3.7.1.14,3.7.1.8,3.7.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 316.0
TH2_k127_618752_4 Creatinase Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004624 276.0
TH2_k127_618752_5 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002484 271.0
TH2_k127_618752_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000001413 243.0
TH2_k127_618752_7 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000003395 208.0
TH2_k127_618752_8 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000001096 204.0
TH2_k127_618752_9 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000004562 178.0
TH2_k127_6192898_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 7.234e-251 787.0
TH2_k127_6192898_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.2e-222 714.0
TH2_k127_6192898_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 400.0
TH2_k127_6192898_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 299.0
TH2_k127_6192898_4 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001248 276.0
TH2_k127_6192898_5 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000129 73.0
TH2_k127_6387786_0 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000004132 187.0
TH2_k127_6387786_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000007548 170.0
TH2_k127_6387786_2 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000003049 156.0
TH2_k127_6387786_3 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000001347 153.0
TH2_k127_6387786_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000006251 62.0
TH2_k127_6387786_5 peptidyl-tyrosine sulfation - - - 0.0006984 52.0
TH2_k127_6425714_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1103.0
TH2_k127_6425714_1 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 301.0
TH2_k127_6425714_2 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000003164 241.0
TH2_k127_6425714_3 response regulator - - - 0.0000000000000000000000000000000141 139.0
TH2_k127_6425714_4 Large extracellular alpha-helical protein K20276 - - 0.00000000000000000000000000006429 130.0
TH2_k127_6425714_5 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.00000000000000000004923 103.0
TH2_k127_6587097_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 7.933e-236 743.0
TH2_k127_6587097_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 514.0
TH2_k127_6724779_0 glycolate transport K14393 - - 5.784e-247 778.0
TH2_k127_6724779_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 3.704e-232 734.0
TH2_k127_6724779_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 575.0
TH2_k127_6724779_3 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 486.0
TH2_k127_6724779_4 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 466.0
TH2_k127_6724779_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000002025 145.0
TH2_k127_6724779_6 membrane - - - 0.00000000000000000000016 99.0
TH2_k127_6858586_0 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 415.0
TH2_k127_6858586_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000006574 191.0
TH2_k127_6858586_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000002039 169.0
TH2_k127_6858586_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000002972 136.0
TH2_k127_6858586_4 iron-sulfur cluster assembly - - - 0.000007835 51.0
TH2_k127_6895812_0 PFAM peptidase M48 Ste24p K07387 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 304.0
TH2_k127_6895812_1 ATPase (AAA superfamily K07133 - - 0.0000000000000000000000000000000000000000000000008015 192.0
TH2_k127_6895812_2 PLD-like domain K06131 - - 0.000000000000000000000000000000000000000005868 157.0
TH2_k127_6895812_3 PFAM ATP-binding region ATPase domain protein K07709 - 2.7.13.3 0.0000000000000000000000000000008018 129.0
TH2_k127_6895812_4 Transcription factor zinc-finger K09981 - - 0.000000000000000000000000004581 112.0
TH2_k127_695616_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 6.79e-197 619.0
TH2_k127_695616_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 9.385e-194 620.0
TH2_k127_695616_10 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000004687 160.0
TH2_k127_695616_11 DUF218 domain - - - 0.000000000000000000000008044 109.0
TH2_k127_695616_12 Phosphopantetheine attachment site K02078,K14661 - - 0.0000000001142 66.0
TH2_k127_695616_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 447.0
TH2_k127_695616_3 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 333.0
TH2_k127_695616_4 PFAM Class II aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 333.0
TH2_k127_695616_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 327.0
TH2_k127_695616_6 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 320.0
TH2_k127_695616_7 Male sterility protein K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002262 282.0
TH2_k127_695616_8 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000001157 231.0
TH2_k127_695616_9 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000001691 183.0
TH2_k127_698152_0 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 563.0
TH2_k127_698152_1 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 468.0
TH2_k127_698152_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 286.0
TH2_k127_7021813_0 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 4.756e-223 703.0
TH2_k127_7021813_1 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 547.0
TH2_k127_7021813_2 - - - - 0.00000000000000000000000000000000000000000000000000001093 192.0
TH2_k127_7118478_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 3.347e-196 625.0
TH2_k127_7118478_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 421.0
TH2_k127_7118478_10 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000006734 129.0
TH2_k127_7118478_11 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000001982 95.0
TH2_k127_7118478_12 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000008873 79.0
TH2_k127_7118478_13 TIGRFAM transcriptional regulator, AbrB family - - - 0.000002107 52.0
TH2_k127_7118478_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 375.0
TH2_k127_7118478_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 319.0
TH2_k127_7118478_4 Carbohydrate-binding family 9 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 280.0
TH2_k127_7118478_5 metal ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000009931 242.0
TH2_k127_7118478_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000005151 189.0
TH2_k127_7118478_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000001668 165.0
TH2_k127_7118478_8 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000007068 163.0
TH2_k127_7118478_9 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000001947 140.0
TH2_k127_712130_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 8.144e-197 623.0
TH2_k127_712130_1 Phosphoenolpyruvate synthase K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 619.0
TH2_k127_712130_10 protocatechuate 3,4-dioxygenase - - - 0.000000000000000000000000000000000000005827 151.0
TH2_k127_712130_11 dolichyl monophosphate biosynthetic process - - - 0.000000000000000000000000000000000166 149.0
TH2_k127_712130_12 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.00000000000000000000000000001764 122.0
TH2_k127_712130_13 Formyl transferase - - - 0.0000000000000000002477 98.0
TH2_k127_712130_2 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 529.0
TH2_k127_712130_3 Hydroxymethylglutaryl-coenzyme A reductase K00021 - 1.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 449.0
TH2_k127_712130_4 Psort location K13622 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 353.0
TH2_k127_712130_5 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 341.0
TH2_k127_712130_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 329.0
TH2_k127_712130_7 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000001739 208.0
TH2_k127_712130_8 HNH nucleases - - - 0.00000000000000000000000000000000000000007592 153.0
TH2_k127_712130_9 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000002672 158.0
TH2_k127_7230399_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.62e-273 856.0
TH2_k127_7230399_1 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 8.361e-202 646.0
TH2_k127_7230399_10 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000001523 261.0
TH2_k127_7230399_11 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000003653 242.0
TH2_k127_7230399_12 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step K05985,K07476 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 0.000000000000000000000000000000000000000009122 158.0
TH2_k127_7230399_13 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000007008 110.0
TH2_k127_7230399_2 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 535.0
TH2_k127_7230399_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 526.0
TH2_k127_7230399_4 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 520.0
TH2_k127_7230399_5 Extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 416.0
TH2_k127_7230399_6 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 417.0
TH2_k127_7230399_7 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 400.0
TH2_k127_7230399_8 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 354.0
TH2_k127_7230399_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005797 282.0
TH2_k127_7268095_0 ATPase BadF BadG BcrA BcrD type - - - 1.288e-236 752.0
TH2_k127_7327284_0 Ammonium Transporter K03320 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 563.0
TH2_k127_7327284_1 - - - - 0.000000000000000000000000000000000000009114 155.0
TH2_k127_7327284_2 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.0000000000000000000000000004325 115.0
TH2_k127_7327284_3 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000006275 57.0
TH2_k127_7327284_4 Belongs to the P(II) protein family K04751 - - 0.00000008929 53.0
TH2_k127_7343734_0 Aminotransferase class-III K01845 - 5.4.3.8 2.53e-198 625.0
TH2_k127_7343734_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000001436 201.0
TH2_k127_7343734_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000003653 129.0
TH2_k127_7343734_3 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.00000000000000000000000002467 111.0
TH2_k127_7343734_4 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000989 92.0
TH2_k127_7410109_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 2.104e-249 794.0
TH2_k127_7493786_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 7.744e-307 963.0
TH2_k127_7493786_1 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 566.0
TH2_k127_7493786_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 497.0
TH2_k127_7493786_3 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 495.0
TH2_k127_7493786_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000000000165 160.0
TH2_k127_7493786_5 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.0000000000000000000000007698 107.0
TH2_k127_7493786_6 phosphatidylglycerophosphatase activity K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.0000000000000000001353 91.0
TH2_k127_7493786_7 ATP synthase, subunit b - - - 0.000000061 58.0
TH2_k127_7493786_8 Modulates RecA activity K03565 - - 0.00000007498 60.0
TH2_k127_7536371_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.207e-229 721.0
TH2_k127_7536371_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.179e-225 708.0
TH2_k127_7536371_10 PDGLE domain K02007 - - 0.0000000000000000000000000000000000000000000001834 170.0
TH2_k127_7536371_11 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000003334 150.0
TH2_k127_7536371_12 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000007993 136.0
TH2_k127_7536371_13 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000001205 117.0
TH2_k127_7536371_14 - - - - 0.000000000000000000000000007783 109.0
TH2_k127_7536371_15 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.00000000000000000000001178 109.0
TH2_k127_7536371_16 Tetratricopeptide repeat-like domain - - - 0.000000000000001636 85.0
TH2_k127_7536371_17 nuclease activity - - - 0.0000000001414 68.0
TH2_k127_7536371_18 Thioredoxin K03672 - 1.8.1.8 0.00003306 53.0
TH2_k127_7536371_19 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000601 43.0
TH2_k127_7536371_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 9.291e-209 669.0
TH2_k127_7536371_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 545.0
TH2_k127_7536371_4 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 540.0
TH2_k127_7536371_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 523.0
TH2_k127_7536371_6 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 485.0
TH2_k127_7536371_7 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 345.0
TH2_k127_7536371_8 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000321 265.0
TH2_k127_7536371_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001063 234.0
TH2_k127_7696684_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 307.0
TH2_k127_7696684_1 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000076 243.0
TH2_k127_7696684_2 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000003389 131.0
TH2_k127_7696684_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000001672 61.0
TH2_k127_7761327_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 424.0
TH2_k127_7761327_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 415.0
TH2_k127_7761327_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 353.0
TH2_k127_7761327_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 315.0
TH2_k127_7842383_0 surface antigen variable number repeat protein K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 548.0
TH2_k127_7842383_1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 405.0
TH2_k127_7842383_10 - - - - 0.000000000000000000000000001198 118.0
TH2_k127_7842383_11 Belongs to the OprB family K07267 - - 0.000000000000000000007122 96.0
TH2_k127_7842383_12 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000006934 64.0
TH2_k127_7842383_13 - - - - 0.000002045 57.0
TH2_k127_7842383_2 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 353.0
TH2_k127_7842383_3 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 310.0
TH2_k127_7842383_4 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000007103 251.0
TH2_k127_7842383_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000004379 200.0
TH2_k127_7842383_6 Cysteine rich repeat - - - 0.0000000000000000000000000000000000000000002847 163.0
TH2_k127_7842383_7 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000001511 161.0
TH2_k127_7842383_8 YMGG-like Gly-zipper - - - 0.00000000000000000000000000000000000002195 149.0
TH2_k127_7842383_9 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000000000005813 141.0
TH2_k127_7843552_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 361.0
TH2_k127_7843552_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000001377 245.0
TH2_k127_7843552_2 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000001478 170.0
TH2_k127_7843552_3 peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000009917 141.0
TH2_k127_7843552_4 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000002475 92.0
TH2_k127_7847363_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 2.264e-232 722.0
TH2_k127_7847363_1 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 528.0
TH2_k127_7847363_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 331.0
TH2_k127_7847363_3 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000003106 248.0
TH2_k127_7847363_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000001698 206.0
TH2_k127_7847363_5 RDD family - - - 0.00000000000000000000000000004098 121.0
TH2_k127_7864769_0 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 359.0
TH2_k127_7864769_1 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000004812 121.0
TH2_k127_7864769_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000003036 94.0
TH2_k127_7905956_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 1.891e-289 911.0
TH2_k127_7905956_1 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 554.0
TH2_k127_7905956_10 Periplasmic or secreted lipoprotein K04065 - - 0.0000001406 57.0
TH2_k127_7905956_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 517.0
TH2_k127_7905956_3 elongation factor Tu domain 2 protein K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 335.0
TH2_k127_7905956_4 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 321.0
TH2_k127_7905956_5 Catalyzes the synthesis of activated sulfate K00860,K00958 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000007383 216.0
TH2_k127_7905956_6 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000001255 130.0
TH2_k127_7905956_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000001356 89.0
TH2_k127_7905956_9 Carboxymuconolactone decarboxylase family - - - 0.0000000016 64.0
TH2_k127_7910134_0 Telomere recombination K04656 - - 1.313e-242 773.0
TH2_k127_7910134_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 486.0
TH2_k127_7910134_10 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 293.0
TH2_k127_7910134_11 nickel cation binding K04651,K19640 - - 0.000000000000000000000000000001606 125.0
TH2_k127_7910134_12 - - - - 0.000000000000000000000000000003046 138.0
TH2_k127_7910134_13 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000001288 106.0
TH2_k127_7910134_14 Tetratricopeptide repeat - - - 0.000000000000000005489 98.0
TH2_k127_7910134_15 Tetratricopeptide repeat - - - 0.00000000000001544 83.0
TH2_k127_7910134_16 Cytochrome c K02305 - - 0.0000000000005561 73.0
TH2_k127_7910134_18 Tetratricopeptide repeat - - - 0.000000001542 61.0
TH2_k127_7910134_19 - - - - 0.0000002932 61.0
TH2_k127_7910134_2 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 469.0
TH2_k127_7910134_3 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 422.0
TH2_k127_7910134_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 406.0
TH2_k127_7910134_5 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 381.0
TH2_k127_7910134_6 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 323.0
TH2_k127_7910134_7 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 316.0
TH2_k127_7910134_9 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 307.0
TH2_k127_7919651_0 Psort location Cytoplasmic, score K07137 - - 8.067e-217 683.0
TH2_k127_7919651_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 501.0
TH2_k127_7919651_10 Universal stress protein family - - - 0.0000000000000000000000000000000000002396 149.0
TH2_k127_7919651_11 proteolysis K03665 - - 0.00000000000000000000000001161 117.0
TH2_k127_7919651_12 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000007279 106.0
TH2_k127_7919651_2 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 323.0
TH2_k127_7919651_3 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 311.0
TH2_k127_7919651_4 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000003829 269.0
TH2_k127_7919651_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000181 257.0
TH2_k127_7919651_6 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000005448 256.0
TH2_k127_7919651_7 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000006201 208.0
TH2_k127_7919651_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000001248 184.0
TH2_k127_7919651_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.0000000000000000000000000000000000000000166 164.0
TH2_k127_7925198_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 1.001e-261 826.0
TH2_k127_7925198_1 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 308.0
TH2_k127_7925198_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 297.0
TH2_k127_7925198_3 Mo-molybdopterin cofactor biosynthetic process - - - 0.00000000000004475 73.0
TH2_k127_7925198_4 DNA protecting protein DprA K04096 - - 0.00000000003605 67.0
TH2_k127_7925198_5 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.000000001461 67.0
TH2_k127_7928597_0 transposition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 446.0
TH2_k127_7928597_1 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 419.0
TH2_k127_7933237_0 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 308.0
TH2_k127_7933237_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001621 282.0
TH2_k127_7933237_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000721 271.0
TH2_k127_7933237_3 cheY-homologous receiver domain - - - 0.0000000000000000000022 99.0
TH2_k127_7933237_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000003633 89.0
TH2_k127_7954666_0 protein secretion K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 565.0
TH2_k127_7954666_1 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 529.0
TH2_k127_7954666_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000002971 103.0
TH2_k127_7987548_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 368.0
TH2_k127_7987548_1 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191 - - 0.00000004684 57.0
TH2_k127_7987548_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000002377 54.0
TH2_k127_7989778_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 396.0
TH2_k127_7989778_1 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000008515 75.0
TH2_k127_7989778_2 Tetratricopeptide repeat - - - 0.000000002576 62.0
TH2_k127_7989778_3 - - - - 0.0000007482 53.0
TH2_k127_8002697_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.505e-241 758.0
TH2_k127_8002697_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 386.0
TH2_k127_8002697_2 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 368.0
TH2_k127_8002697_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000001621 207.0
TH2_k127_8018597_0 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000006557 198.0
TH2_k127_8018597_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000001481 156.0
TH2_k127_8018597_2 SEC-C Motif Domain Protein - - - 0.0001392 50.0
TH2_k127_8018597_3 Tetratricopeptide repeat protein - - - 0.0002263 49.0
TH2_k127_8083404_0 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 611.0
TH2_k127_8083404_1 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 316.0
TH2_k127_8083404_2 Amino acid ABC transporter substrate-binding protein K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001445 270.0
TH2_k127_8083404_3 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000003915 231.0
TH2_k127_8083404_4 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000001871 220.0
TH2_k127_8096123_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 425.0
TH2_k127_8096123_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 341.0
TH2_k127_8096123_2 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 287.0
TH2_k127_8096123_3 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000139 203.0
TH2_k127_8096123_4 Cell division protein FtsQ K03589 - - 0.000000003733 67.0
TH2_k127_8191853_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 5.929e-288 896.0
TH2_k127_8191853_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 379.0
TH2_k127_8191853_2 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000002167 231.0
TH2_k127_8191853_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000004252 204.0
TH2_k127_8191853_4 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000004451 181.0
TH2_k127_8191853_5 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000481 160.0
TH2_k127_8191853_6 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000003371 59.0
TH2_k127_8205775_0 Domain of unknown function (DUF4139) - - - 1.234e-204 647.0
TH2_k127_8205775_1 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000002329 198.0
TH2_k127_8205775_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000368 191.0
TH2_k127_8205775_3 Putative zinc-finger - - - 0.0000000000000000000003989 108.0
TH2_k127_8205775_4 Histidine kinase - - - 0.000000000000000002446 87.0
TH2_k127_8205775_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000005086 61.0
TH2_k127_8212905_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 4.294e-310 965.0
TH2_k127_8212905_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.959e-285 885.0
TH2_k127_8212905_2 Dehydratase family K01687 - 4.2.1.9 2.022e-258 806.0
TH2_k127_8212905_3 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000007626 257.0
TH2_k127_8212905_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000006943 138.0
TH2_k127_8212905_5 Ubiquinol--cytochrome c reductase - - - 0.00000000000000000000000000006933 116.0
TH2_k127_8212905_6 - - - - 0.00000000000000002124 85.0
TH2_k127_8212905_7 Transcriptional regulator - - - 0.0000000000000363 75.0
TH2_k127_8212905_8 Evidence 4 Homologs of previously reported genes of - - - 0.000000000004216 68.0
TH2_k127_8241956_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182,K16239,K16874 - 4.1.1.61,4.1.1.98 4.325e-211 667.0
TH2_k127_8241956_1 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 449.0
TH2_k127_8241956_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 411.0
TH2_k127_8241956_3 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 330.0
TH2_k127_8241956_4 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000001398 239.0
TH2_k127_8241956_5 - K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000002117 210.0
TH2_k127_8241956_6 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000351 207.0
TH2_k127_8241956_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000003097 130.0
TH2_k127_8241956_8 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000001947 121.0
TH2_k127_8241956_9 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000002159 113.0
TH2_k127_8242703_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.552e-283 881.0
TH2_k127_8242703_1 Enoyl-(Acyl carrier protein) reductase - - - 4.555e-226 710.0
TH2_k127_8242703_11 Sporulation and spore germination - - - 0.00000000005928 70.0
TH2_k127_8242703_2 Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 383.0
TH2_k127_8242703_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 355.0
TH2_k127_8242703_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 323.0
TH2_k127_8242703_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 313.0
TH2_k127_8242703_6 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 336.0
TH2_k127_8242703_7 PIN domain - - - 0.00000000000000000000000000000000006264 139.0
TH2_k127_8242703_8 Transport permease protein K01992 - - 0.000000000000000000001532 98.0
TH2_k127_8242703_9 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000001147 101.0
TH2_k127_8290680_0 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002888 297.0
TH2_k127_8290680_1 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.00000000000000000001407 92.0
TH2_k127_8290680_2 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000002238 65.0
TH2_k127_8306097_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 341.0
TH2_k127_8306097_1 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 292.0
TH2_k127_8306097_2 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006599 278.0
TH2_k127_8306097_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000004125 168.0
TH2_k127_8306097_4 Methylamine utilisation protein MauE - - - 0.000000000000002454 83.0
TH2_k127_8306097_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000007717 63.0
TH2_k127_8313907_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2072.0
TH2_k127_8313907_1 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1628.0
TH2_k127_8313907_10 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000001089 74.0
TH2_k127_8313907_11 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000002438 74.0
TH2_k127_8313907_12 Belongs to the 'phage' integrase family K04763 - - 0.0000000000957 67.0
TH2_k127_8313907_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 329.0
TH2_k127_8313907_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001157 259.0
TH2_k127_8313907_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000002394 219.0
TH2_k127_8313907_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000007544 189.0
TH2_k127_8313907_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000001116 136.0
TH2_k127_8313907_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000003131 143.0
TH2_k127_8313907_8 nuclease activity K18828 - - 0.00000000000000000000000000005272 121.0
TH2_k127_8313907_9 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000531 110.0
TH2_k127_8328880_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 511.0
TH2_k127_8328880_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 441.0
TH2_k127_8328880_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 322.0
TH2_k127_833607_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 587.0
TH2_k127_833607_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 565.0
TH2_k127_833607_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 525.0
TH2_k127_833607_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 323.0
TH2_k127_833607_4 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000007062 235.0
TH2_k127_833607_5 TIGRFAM PAS domain S-box - - - 0.000000000000000000000000000000000000000000000000000000000000007663 236.0
TH2_k127_833607_6 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000003342 151.0
TH2_k127_833607_7 RNA-binding protein - - - 0.00000000000000000000001237 104.0
TH2_k127_833607_8 PFAM Lytic transglycosylase catalytic - - - 0.000000004256 66.0
TH2_k127_833607_9 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0004828 44.0
TH2_k127_8337588_0 ABC transporter K06158 - - 9.871e-235 741.0
TH2_k127_8337588_1 Rhodanese Homology Domain - - - 0.0000000000000003142 79.0
TH2_k127_8359311_0 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 384.0
TH2_k127_8359311_1 - K00712 - 2.4.1.52 0.00000000000000000000000000000000000000000000000000000001982 225.0
TH2_k127_8359311_2 Cytochrome C assembly protein - - - 0.0000000000000007631 80.0
TH2_k127_8386557_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 533.0
TH2_k127_8386557_1 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 394.0
TH2_k127_8386557_2 nitrogen fixation sensor protein fixL K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000003071 261.0
TH2_k127_8386557_3 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000000007971 119.0
TH2_k127_8386557_4 TQO small subunit DoxD K15977 - - 0.000000000000000000008822 97.0
TH2_k127_8386557_5 Peptidase family M23 - - - 0.000000005406 57.0
TH2_k127_843878_0 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 351.0
TH2_k127_843878_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000001993 225.0
TH2_k127_843878_2 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000001767 193.0
TH2_k127_843878_3 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000000000000000000000003168 179.0
TH2_k127_843878_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000173 85.0
TH2_k127_8446209_0 FecR protein - - - 2.902e-299 951.0
TH2_k127_8446209_1 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 627.0
TH2_k127_8446209_10 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.000000000000000000000000000000006173 133.0
TH2_k127_8446209_11 thiolester hydrolase activity - - - 0.00000000000000000000000000000007974 129.0
TH2_k127_8446209_12 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000001919 111.0
TH2_k127_8446209_13 Glutathionylspermidine synthase preATP-grasp - - - 0.00000000000000000000003748 101.0
TH2_k127_8446209_14 protein-glutamate O-methyltransferase activity K00575,K03408,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000007773 94.0
TH2_k127_8446209_2 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 397.0
TH2_k127_8446209_3 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 381.0
TH2_k127_8446209_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000001051 244.0
TH2_k127_8446209_5 DegT/DnrJ/EryC1/StrS aminotransferase family K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000006207 233.0
TH2_k127_8446209_6 - - - - 0.00000000000000000000000000000000000000000000000000000002506 208.0
TH2_k127_8446209_7 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000000000000000138 198.0
TH2_k127_8446209_8 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000002578 210.0
TH2_k127_8446209_9 Domain of Unknown Function (DUF350) K08989 - - 0.0000000000000000000000000000000003945 137.0
TH2_k127_87370_0 DHHA2 domain K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 551.0
TH2_k127_87370_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 427.0
TH2_k127_87370_2 PFAM Integrase core domain - - - 0.0000000001271 64.0