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Overview

ID MAG03916
Name TH2_bin.52
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Bacteroidota
Class Bacteroidia
Order B-17B0
Family B-17BO
Genus JAHEYG01
Species
Assembly information
Completeness (%) 100.0
Contamination (%) 2.1
GC content (%) 37.0
N50 (bp) 26,822
Genome size (bp) 3,182,415

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2592

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1001271_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 479.0
TH2_k127_1099800_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 6.109e-237 742.0
TH2_k127_1099800_1 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 1.078e-198 629.0
TH2_k127_1099800_10 peptidyl-tyrosine sulfation - - - 0.00005047 47.0
TH2_k127_1099800_2 SprB repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 368.0
TH2_k127_1099800_3 ThiF family K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 307.0
TH2_k127_1099800_4 Domains in Na-Ca exchangers and integrin-beta4 - - - 0.0000000000000000000000000000000000000000000000000000000000000002162 239.0
TH2_k127_1099800_5 PFAM TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000001206 170.0
TH2_k127_1099800_6 C-terminal domain of CHU protein family - - - 0.0000000000000000000000007034 122.0
TH2_k127_1099800_7 Dehydrogenase K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000001197 58.0
TH2_k127_1099800_8 TIGRFAM RHS repeat-associated core domain - - - 0.00000004108 66.0
TH2_k127_1099800_9 - - - - 0.00001485 55.0
TH2_k127_1124202_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0 1069.0
TH2_k127_1124202_1 Nitrite and sulphite reductase 4Fe-4S K00392 - 1.8.7.1 3.222e-268 843.0
TH2_k127_1124202_10 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01740,K10764 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 547.0
TH2_k127_1124202_11 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 531.0
TH2_k127_1124202_12 Sirohaem biosynthesis protein central K02304,K07090 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 473.0
TH2_k127_1124202_13 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 394.0
TH2_k127_1124202_14 metallocarboxypeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 400.0
TH2_k127_1124202_15 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 330.0
TH2_k127_1124202_16 PFAM NAD dependent epimerase dehydratase family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 332.0
TH2_k127_1124202_17 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303,K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 297.0
TH2_k127_1124202_18 COGs COG0663 Carbonic anhydrase acetyltransferase isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 290.0
TH2_k127_1124202_19 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002489 278.0
TH2_k127_1124202_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 5.592e-245 765.0
TH2_k127_1124202_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004051 258.0
TH2_k127_1124202_21 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006988 276.0
TH2_k127_1124202_22 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000003591 239.0
TH2_k127_1124202_23 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000006091 220.0
TH2_k127_1124202_24 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000002145 209.0
TH2_k127_1124202_25 TIGRFAM Rrf2 family protein - - - 0.00000000000000000000000000000000000000000000000000001964 192.0
TH2_k127_1124202_26 Iron dependent repressor, metal binding and dimerisation domain K03709 - - 0.00000000000000000000000000000000000000000000003366 177.0
TH2_k127_1124202_27 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000000000000000007367 175.0
TH2_k127_1124202_28 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000001158 160.0
TH2_k127_1124202_29 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000004032 153.0
TH2_k127_1124202_3 TonB-dependent receptor K02014,K16089 - - 7.853e-239 756.0
TH2_k127_1124202_30 - - - - 0.0000000000000000000000000000000000000009978 153.0
TH2_k127_1124202_31 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000000001443 149.0
TH2_k127_1124202_32 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA - - - 0.0000000000000000000000000000000000001308 145.0
TH2_k127_1124202_34 - - - - 0.00000000000000000001656 96.0
TH2_k127_1124202_4 PFAM TonB-dependent Receptor K16091 - - 3.587e-208 677.0
TH2_k127_1124202_5 Peptidase M1, membrane alanine aminopeptidase - - - 8.418e-203 645.0
TH2_k127_1124202_6 tRNA synthetase class II core domain (G, H, P, S and T) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 606.0
TH2_k127_1124202_7 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 601.0
TH2_k127_1124202_8 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 573.0
TH2_k127_1124202_9 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 566.0
TH2_k127_1190798_0 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.0 1177.0
TH2_k127_1190798_1 COGs COG0659 Sulfate permease and related transporter (MFS superfamily) - - - 3.89e-229 719.0
TH2_k127_1190798_10 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 351.0
TH2_k127_1190798_11 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005316 281.0
TH2_k127_1190798_12 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001594 277.0
TH2_k127_1190798_13 uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000001548 242.0
TH2_k127_1190798_14 Receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000001867 243.0
TH2_k127_1190798_15 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000001532 233.0
TH2_k127_1190798_16 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.000000000000000000000000000000000000000000000000000000000001794 222.0
TH2_k127_1190798_17 DinB superfamily - - - 0.0000000000000000000000000000000000000000004511 162.0
TH2_k127_1190798_18 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 - 2.1.1.63 0.00000000000000000000000000000000000000004178 153.0
TH2_k127_1190798_19 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000007524 164.0
TH2_k127_1190798_2 NADH ubiquinone oxidoreductase subunit 5 (chain L) multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 5.555e-216 687.0
TH2_k127_1190798_20 - - - - 0.0000682 52.0
TH2_k127_1190798_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 1.166e-201 634.0
TH2_k127_1190798_4 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 594.0
TH2_k127_1190798_5 Tetratricopeptide repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 600.0
TH2_k127_1190798_6 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 510.0
TH2_k127_1190798_7 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 473.0
TH2_k127_1190798_8 PFAM Acyl-protein synthetase, LuxE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 391.0
TH2_k127_1190798_9 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 383.0
TH2_k127_1214917_0 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 532.0
TH2_k127_1214917_1 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 417.0
TH2_k127_1214917_2 Belongs to the 'phage' integrase family K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 307.0
TH2_k127_1214917_3 PFAM Sigma 54 modulation protein S30EA ribosomal protein K05808 - - 0.000000000000000000000000005113 113.0
TH2_k127_1214917_4 Ribosomal protein S21 K02970 - - 0.00000000000000000766 84.0
TH2_k127_1214917_5 phosphoserine phosphatase activity - - - 0.000000000001843 68.0
TH2_k127_1229030_0 Peptidase family M1 domain - - - 0.0 1010.0
TH2_k127_1229030_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004044 270.0
TH2_k127_1229030_2 domain, Protein K20276,K21449 - - 0.00000000000000000000000000000000000000000000002497 195.0
TH2_k127_1229030_3 ABC transporter ATP-binding protein - - - 0.00000000000000000000000000000000000000000000009908 185.0
TH2_k127_1229030_4 HupE / UreJ protein - - - 0.000000000000000000000000000000000000002229 153.0
TH2_k127_1229030_5 Biotin-lipoyl like - - - 0.00000000000000000000000000005975 131.0
TH2_k127_1229030_6 - - - - 0.0000000000000000000000000001616 122.0
TH2_k127_1272852_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 7.708e-246 763.0
TH2_k127_1272852_1 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 475.0
TH2_k127_1272852_10 TIGRFAM Gliding motility-associated lipoprotein, GldH - GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000007374 117.0
TH2_k127_1272852_11 Belongs to the P-Pant transferase superfamily - - - 0.0000000000000000000000001864 113.0
TH2_k127_1272852_12 COG2143 Thioredoxin-related protein - - - 0.000000000000001597 88.0
TH2_k127_1272852_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 318.0
TH2_k127_1272852_3 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 302.0
TH2_k127_1272852_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000004351 195.0
TH2_k127_1272852_5 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P) K07094 - - 0.00000000000000000000000000000000000000000000000000000235 198.0
TH2_k127_1272852_6 EVE domain - - - 0.000000000000000000000000000000000000000000000000007846 183.0
TH2_k127_1272852_7 domain, Protein - - - 0.0000000000000000000000000000000000000000006627 169.0
TH2_k127_1272852_8 COG2143 Thioredoxin-related protein - - - 0.00000000000000000000000000000005797 138.0
TH2_k127_1272852_9 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000009369 123.0
TH2_k127_136586_0 C-terminal domain of CHU protein family K01337 - 3.4.21.50 1.2e-283 909.0
TH2_k127_136586_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 6.019e-261 810.0
TH2_k127_136586_10 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 384.0
TH2_k127_136586_11 glucosamine N-acyltransferase K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 382.0
TH2_k127_136586_12 TonB-dependent receptor K02014,K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 380.0
TH2_k127_136586_13 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 380.0
TH2_k127_136586_14 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 355.0
TH2_k127_136586_15 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 339.0
TH2_k127_136586_16 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 320.0
TH2_k127_136586_17 Pectate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003528 299.0
TH2_k127_136586_18 Psort location Cytoplasmic, score 8.96 K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000002016 252.0
TH2_k127_136586_19 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000139 203.0
TH2_k127_136586_2 C-terminal domain of CHU protein family - - - 1.134e-226 729.0
TH2_k127_136586_20 - - - - 0.00000000000000000000000000000000000000000000000000000002292 204.0
TH2_k127_136586_21 phosphate ion binding - - - 0.0000000000000000000000000000000000000000000000000000001835 209.0
TH2_k127_136586_22 PFAM Outer membrane protein transport protein (OMPP1 FadL TodX) - - - 0.000000000000000000000000000000000000000000000000000177 204.0
TH2_k127_136586_23 Chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000002573 197.0
TH2_k127_136586_24 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000001356 186.0
TH2_k127_136586_25 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.0000000000000000000000000000000000000000000000006238 179.0
TH2_k127_136586_26 pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000001572 167.0
TH2_k127_136586_27 PFAM PKD domain - - - 0.0000000000000000000000000000000000000000002702 185.0
TH2_k127_136586_28 COG3209 Rhs family protein - - - 0.000000000000000000000000000000002206 136.0
TH2_k127_136586_29 protein involved in exopolysaccharide biosynthesis - - - 0.00000000000000000000000000004671 128.0
TH2_k127_136586_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 4.184e-199 631.0
TH2_k127_136586_30 Ferredoxin - - - 0.0000000000000000000000000001047 117.0
TH2_k127_136586_31 C-terminal domain of CHU protein family - - - 0.00000000000001079 91.0
TH2_k127_136586_33 - - - - 0.000000001023 64.0
TH2_k127_136586_35 - - - - 0.00000161 56.0
TH2_k127_136586_4 Immunoglobulin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 647.0
TH2_k127_136586_5 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 540.0
TH2_k127_136586_6 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 535.0
TH2_k127_136586_7 PFAM PKD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 533.0
TH2_k127_136586_8 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008308 417.0
TH2_k127_136586_9 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 400.0
TH2_k127_1406056_0 GTP-binding protein TypA K06207 - - 9.418e-307 948.0
TH2_k127_1406056_1 geranylgeranyl reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 604.0
TH2_k127_1406056_10 - - - - 0.00000000003558 74.0
TH2_k127_1406056_11 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000008138 63.0
TH2_k127_1406056_2 Domain of unknown function (DUF4872) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 482.0
TH2_k127_1406056_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001284 256.0
TH2_k127_1406056_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000438 246.0
TH2_k127_1406056_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000001872 189.0
TH2_k127_1406056_6 - - - - 0.00000000000000000000000000000000000000000000000000002768 190.0
TH2_k127_1406056_7 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K20866 - 3.1.3.10 0.000000000000000000000000000000000000000000000000002694 188.0
TH2_k127_1406056_8 Endonuclease I - - - 0.000000000000000000000000000000000000006829 168.0
TH2_k127_1406056_9 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000004336 132.0
TH2_k127_1432228_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 586.0
TH2_k127_1432228_1 Aminotransferase class-V K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 555.0
TH2_k127_1432228_10 long-chain fatty acid transporting porin activity - - - 0.00001448 56.0
TH2_k127_1432228_11 Pkd domain containing protein - - - 0.00001667 57.0
TH2_k127_1432228_12 Tetratricopeptide repeats - - - 0.00008034 55.0
TH2_k127_1432228_2 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000198 278.0
TH2_k127_1432228_3 alpha beta K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000152 277.0
TH2_k127_1432228_4 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000001621 265.0
TH2_k127_1432228_5 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000003771 217.0
TH2_k127_1432228_6 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000002503 167.0
TH2_k127_1432228_7 - - - - 0.00000000000000000000000000000000000002633 156.0
TH2_k127_1432228_8 COGs COG0791 Cell wall-associated hydrolase (invasion-associated protein) K21471 - - 0.0000000000000000000000000000000000005125 144.0
TH2_k127_1432228_9 Bacterial Ig-like domain (group 3) - - - 0.000000000000000000000000001522 128.0
TH2_k127_1476622_0 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 571.0
TH2_k127_1476622_1 Fe-S oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 548.0
TH2_k127_1476622_10 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001351 243.0
TH2_k127_1476622_11 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000008657 249.0
TH2_k127_1476622_12 PFAM Uncharacterised protein family UPF0029, Impact, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000001642 224.0
TH2_k127_1476622_13 - - - - 0.00000000000000000000000000000000000000000000000007533 188.0
TH2_k127_1476622_14 domain protein - - - 0.00000000000000000000000000000000000000002807 174.0
TH2_k127_1476622_15 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000003263 155.0
TH2_k127_1476622_16 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000003946 159.0
TH2_k127_1476622_17 Transcriptional regulator - - - 0.0000000000000000000000000000002241 126.0
TH2_k127_1476622_2 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 432.0
TH2_k127_1476622_3 PFAM M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 413.0
TH2_k127_1476622_4 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 376.0
TH2_k127_1476622_5 COGs COG1668 ABC-type Na efflux pump permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 331.0
TH2_k127_1476622_6 Domain of Unknown Function (DUF349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 322.0
TH2_k127_1476622_7 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 304.0
TH2_k127_1476622_8 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008858 259.0
TH2_k127_1476622_9 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001141 253.0
TH2_k127_1478460_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 8.588e-260 811.0
TH2_k127_1478460_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 7.523e-200 640.0
TH2_k127_1478460_10 protein kinase activity - - - 0.00000000000000000000000003143 124.0
TH2_k127_1478460_12 nitrite reductase [NAD(P)H] activity K03651 - 3.1.4.53 0.000000000002494 72.0
TH2_k127_1478460_13 TM2 domain - - - 0.000000000182 67.0
TH2_k127_1478460_14 C-terminal domain of CHU protein family - - - 0.000001295 60.0
TH2_k127_1478460_15 GIY-YIG catalytic domain K07461 - - 0.000006978 48.0
TH2_k127_1478460_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 504.0
TH2_k127_1478460_3 mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 420.0
TH2_k127_1478460_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 334.0
TH2_k127_1478460_5 Domain of unknown function (4846) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 292.0
TH2_k127_1478460_6 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000001397 207.0
TH2_k127_1478460_7 TIGRFAM gliding motility-associated lipoprotein GldD - - - 0.0000000000000000000000000000000000000000000000000000000002707 210.0
TH2_k127_1478460_8 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000001637 160.0
TH2_k127_1478460_9 LysM domain - - - 0.000000000000000000000000000000000002676 156.0
TH2_k127_149339_0 Belongs to the ompA family - - - 2.39e-207 673.0
TH2_k127_149339_1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 3.401e-201 634.0
TH2_k127_149339_10 - - - - 0.0000000000000001657 84.0
TH2_k127_149339_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 464.0
TH2_k127_149339_3 Phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 398.0
TH2_k127_149339_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 286.0
TH2_k127_149339_5 Low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000003494 185.0
TH2_k127_149339_6 S-adenosyl-l-methionine hydroxide adenosyltransferase - - - 0.0000000000000000000000000000000000000000002815 168.0
TH2_k127_149339_7 negative regulation of translational initiation K13652 - - 0.000000000000000000000000000000000000007905 158.0
TH2_k127_149339_8 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000001415 119.0
TH2_k127_149339_9 Thioesterase superfamily - - - 0.0000000000000000000000004165 109.0
TH2_k127_1518633_0 Nitrous oxide reductase K00376 - 1.7.2.4 0.0 1122.0
TH2_k127_1518633_1 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 546.0
TH2_k127_1518633_2 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 522.0
TH2_k127_1518633_3 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 377.0
TH2_k127_1518633_4 nitrous oxide K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 347.0
TH2_k127_1518633_5 ABC-type multidrug transport system ATPase component K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 338.0
TH2_k127_1518633_6 PFAM cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000002952 224.0
TH2_k127_1518633_7 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000000000000000000244 205.0
TH2_k127_1518633_8 Argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000003099 169.0
TH2_k127_1520782_0 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 318.0
TH2_k127_1520782_1 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.0000000000000000000000000000000006323 143.0
TH2_k127_1520782_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000007229 91.0
TH2_k127_1527608_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.978e-205 646.0
TH2_k127_1527608_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.499e-194 612.0
TH2_k127_1527608_10 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000001343 247.0
TH2_k127_1527608_11 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000006239 189.0
TH2_k127_1527608_12 chlorophyll binding - - - 0.0000000000000000000000000000000000000001178 173.0
TH2_k127_1527608_13 Rieske (2Fe-2S) domain K05710 - - 0.0000000000000000000004346 102.0
TH2_k127_1527608_14 - - - - 0.000000000000000007886 95.0
TH2_k127_1527608_16 Bacterial transcription activator, effector binding domain K13652 - - 0.00002289 54.0
TH2_k127_1527608_2 PFAM Aminotransferase class I and II K00812,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 569.0
TH2_k127_1527608_3 type III restriction enzyme, res subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 546.0
TH2_k127_1527608_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 467.0
TH2_k127_1527608_5 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 349.0
TH2_k127_1527608_6 dihydropteroate synthase K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003222 283.0
TH2_k127_1527608_7 Doxx family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003077 274.0
TH2_k127_1527608_8 Domain of Unknown Function (DUF1599) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003917 256.0
TH2_k127_1527608_9 NusB family K03625 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001734 261.0
TH2_k127_1573740_0 potassium channel beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 462.0
TH2_k127_1573740_1 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 424.0
TH2_k127_1573740_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 381.0
TH2_k127_1573740_3 Putative thioesterase (yiiD_Cterm) - GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 - 0.00000000000000000000000000002926 121.0
TH2_k127_162163_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1256.0
TH2_k127_162163_1 Alpha-2-Macroglobulin K06894 - - 1.912e-224 726.0
TH2_k127_162163_2 signal peptide peptidase SppA, 67K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 581.0
TH2_k127_162163_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 535.0
TH2_k127_162163_4 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 456.0
TH2_k127_162163_5 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 349.0
TH2_k127_162163_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000001027 181.0
TH2_k127_162163_7 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.000000000000000000000000000000000000001655 153.0
TH2_k127_162163_8 Pfam 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000003857 153.0
TH2_k127_162163_9 - - - - 0.0000000000000006517 86.0
TH2_k127_1701204_0 Belongs to the type II topoisomerase GyrA ParC subunit family K02621 - - 0.0 1074.0
TH2_k127_1701204_1 DNA Topoisomerase K02622 - - 1.459e-297 922.0
TH2_k127_1701204_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 406.0
TH2_k127_1701204_11 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 400.0
TH2_k127_1701204_12 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 368.0
TH2_k127_1701204_13 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 363.0
TH2_k127_1701204_14 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 350.0
TH2_k127_1701204_15 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 326.0
TH2_k127_1701204_16 PFAM Peptidase, membrane zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006304 267.0
TH2_k127_1701204_17 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000002527 243.0
TH2_k127_1701204_18 Glycoprotease family K14742 - - 0.000000000000000000000000000000000000000000000000000000000009265 214.0
TH2_k127_1701204_19 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000001004 157.0
TH2_k127_1701204_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 5.432e-244 771.0
TH2_k127_1701204_20 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000001216 141.0
TH2_k127_1701204_21 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000001777 134.0
TH2_k127_1701204_22 RNA recognition motif - - - 0.00000000000000000005986 92.0
TH2_k127_1701204_24 Tellurite resistance protein TerB - - - 0.0000000004472 65.0
TH2_k127_1701204_25 - - - - 0.000127 52.0
TH2_k127_1701204_3 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 1.635e-226 720.0
TH2_k127_1701204_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 607.0
TH2_k127_1701204_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 569.0
TH2_k127_1701204_6 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 510.0
TH2_k127_1701204_7 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 462.0
TH2_k127_1701204_8 Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 434.0
TH2_k127_1701204_9 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 424.0
TH2_k127_171894_0 DEAD DEAH box helicase K03579 - 3.6.4.13 0.0 1168.0
TH2_k127_171894_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06132 - - 4.123e-241 753.0
TH2_k127_171894_2 Formate/nitrite transporter K06212 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 312.0
TH2_k127_171894_3 Ceramidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004462 244.0
TH2_k127_171894_4 yiaA/B two helix domain - - - 0.000000000000000000000000000000000000000000000000000000000513 204.0
TH2_k127_171894_5 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000196 200.0
TH2_k127_171894_6 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - 0.0000000000000000000000000000000000000000000004625 172.0
TH2_k127_171894_7 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000000000001002 139.0
TH2_k127_174927_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 4.602e-284 894.0
TH2_k127_174927_1 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.074e-275 859.0
TH2_k127_174927_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.342e-275 854.0
TH2_k127_174927_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 477.0
TH2_k127_174927_4 PFAM Pregnancy-associated plasma protein-A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 389.0
TH2_k127_174927_5 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000002117 243.0
TH2_k127_174927_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000001304 157.0
TH2_k127_174927_7 by modhmm K03655 - 3.6.4.12 0.000000000000000000000000000000006005 146.0
TH2_k127_174927_8 SAM-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000005189 91.0
TH2_k127_1759001_0 Putative tRNA binding domain K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 2.485e-317 983.0
TH2_k127_1759001_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 4.264e-196 618.0
TH2_k127_1759001_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 306.0
TH2_k127_1759001_11 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006301 295.0
TH2_k127_1759001_12 Ndr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000236 258.0
TH2_k127_1759001_13 lipid kinase, YegS Rv2252 BmrU family - - - 0.00000000000000000000000000000000000000000000000000000000000000000557 237.0
TH2_k127_1759001_14 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000001659 229.0
TH2_k127_1759001_15 - - - - 0.00000000000000000000000000000000000000000000000001009 194.0
TH2_k127_1759001_16 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000009041 196.0
TH2_k127_1759001_17 NUMOD4 motif - - - 0.000000000000000000000000000000005987 135.0
TH2_k127_1759001_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 600.0
TH2_k127_1759001_3 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 607.0
TH2_k127_1759001_4 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 530.0
TH2_k127_1759001_5 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 482.0
TH2_k127_1759001_6 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 398.0
TH2_k127_1759001_7 Peptidase S66 K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 343.0
TH2_k127_1759001_8 alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 333.0
TH2_k127_1759001_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007131 285.0
TH2_k127_176384_0 DNA polymerase alpha chain like domain K02337 - 2.7.7.7 0.0 1191.0
TH2_k127_176384_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1085.0
TH2_k127_176384_10 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000002343 215.0
TH2_k127_176384_11 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000006572 215.0
TH2_k127_176384_12 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000002879 199.0
TH2_k127_176384_13 MORN repeat variant - - - 0.00000000000000000000000000000000000000000002614 173.0
TH2_k127_176384_14 - - - - 0.00000000000000000000000000000000000000000007966 164.0
TH2_k127_176384_15 MORN repeat variant - - - 0.000000000000000000000000000000000005585 148.0
TH2_k127_176384_16 Phosphopantetheine attachment site K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000007416 131.0
TH2_k127_176384_17 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000002579 134.0
TH2_k127_176384_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.648e-314 986.0
TH2_k127_176384_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 1.722e-235 737.0
TH2_k127_176384_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.525e-201 634.0
TH2_k127_176384_5 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 594.0
TH2_k127_176384_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 537.0
TH2_k127_176384_7 NAD-dependent epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 433.0
TH2_k127_176384_8 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 378.0
TH2_k127_176384_9 PFAM Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 312.0
TH2_k127_1834385_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1253.0
TH2_k127_1834385_1 reductase K00526 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 547.0
TH2_k127_1834385_2 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002512 299.0
TH2_k127_1834385_3 extracellular polysaccharide biosynthetic process K13582 - - 0.0000000000000000000000000000000000000000000000009788 186.0
TH2_k127_1834385_4 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000005762 75.0
TH2_k127_19869_0 - - - - 7.228e-274 897.0
TH2_k127_19869_1 - - - - 7.896e-268 876.0
TH2_k127_19869_10 Domain of unknown function (DUF4131) K02238 - - 0.00000000000000000000000000000000000000000000000000000000007136 228.0
TH2_k127_19869_11 Transcription elongation factor, N-terminal K03624 - - 0.000000000000000000000000000000000000000000000000000000000167 207.0
TH2_k127_19869_12 HIT family hydrolase K02503 - - 0.0000000000000000000000000000000000000000000000000002452 188.0
TH2_k127_19869_13 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000000000000000000000000000000000008934 192.0
TH2_k127_19869_14 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000001202 169.0
TH2_k127_19869_15 chain release factor K15034 - - 0.00000000000000000000000004456 112.0
TH2_k127_19869_16 lipolytic protein G-D-S-L family - - - 0.000000006053 67.0
TH2_k127_19869_2 Peptidase family C25 - - - 6.966e-201 673.0
TH2_k127_19869_3 C-terminal domain of CHU protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 483.0
TH2_k127_19869_4 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 361.0
TH2_k127_19869_5 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 338.0
TH2_k127_19869_6 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 318.0
TH2_k127_19869_7 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 312.0
TH2_k127_19869_8 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002139 252.0
TH2_k127_19869_9 TIGRFAM Bacteroidetes-specific - - - 0.00000000000000000000000000000000000000000000000000000000000000000006401 243.0
TH2_k127_2125591_0 Protein of unknown function (DUF3584) - - - 6.73e-280 902.0
TH2_k127_2125591_1 PFAM Cys Met metabolism PLP-dependent enzyme K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 2.201e-223 696.0
TH2_k127_2125591_2 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member K01144 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 471.0
TH2_k127_2125591_3 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 406.0
TH2_k127_2125591_4 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 312.0
TH2_k127_2125591_5 Halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003728 248.0
TH2_k127_2125591_6 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000001099 154.0
TH2_k127_2125591_7 - - - - 0.000000000000000000165 95.0
TH2_k127_2145119_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 330.0
TH2_k127_2145119_1 periplasmic ligand-binding sensor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 301.0
TH2_k127_2145119_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000006109 151.0
TH2_k127_2180382_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 503.0
TH2_k127_2180382_1 AMP-binding enzyme K03367 - 6.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 411.0
TH2_k127_2180382_2 Alginate O-acetylation protein K03739 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004066 248.0
TH2_k127_2180382_3 - - - - 0.0000001598 59.0
TH2_k127_2225042_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 1.193e-204 646.0
TH2_k127_2225042_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 1.063e-202 638.0
TH2_k127_2225042_10 PFAM von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 392.0
TH2_k127_2225042_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 366.0
TH2_k127_2225042_12 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 361.0
TH2_k127_2225042_13 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002721 279.0
TH2_k127_2225042_14 Transcriptional regulator, LacI family K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000002999 241.0
TH2_k127_2225042_15 PFAM SprT-like family - - - 0.000000000000000000000000000000000000000000000000000000000007547 214.0
TH2_k127_2225042_16 Cell division protein K03589 - - 0.0000000000000000000000000000000000000000001029 169.0
TH2_k127_2225042_17 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000000000008363 159.0
TH2_k127_2225042_18 YqeY-like protein K09117 - - 0.0000000000000000000000000000000000007452 143.0
TH2_k127_2225042_19 - - - - 0.00000000000000000001245 97.0
TH2_k127_2225042_2 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 9.696e-197 635.0
TH2_k127_2225042_20 - - - - 0.000000000000009541 81.0
TH2_k127_2225042_21 PFAM Pregnancy-associated plasma protein-A - - - 0.00000000001087 78.0
TH2_k127_2225042_22 Membrane-bound lysozyme-inhibitor of c-type lysozyme K08985 - - 0.0002986 49.0
TH2_k127_2225042_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 606.0
TH2_k127_2225042_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 591.0
TH2_k127_2225042_5 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 554.0
TH2_k127_2225042_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 538.0
TH2_k127_2225042_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 501.0
TH2_k127_2225042_8 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 471.0
TH2_k127_2225042_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 443.0
TH2_k127_23611_0 Tex-like protein N-terminal domain K06959 - - 3.888e-314 977.0
TH2_k127_23611_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 6.883e-298 921.0
TH2_k127_23611_10 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 455.0
TH2_k127_23611_11 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 454.0
TH2_k127_23611_12 PFAM Peptidase family M1 K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 464.0
TH2_k127_23611_13 COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 479.0
TH2_k127_23611_14 Transglycosylase SLT domain K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 427.0
TH2_k127_23611_15 Arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 400.0
TH2_k127_23611_16 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 402.0
TH2_k127_23611_17 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 392.0
TH2_k127_23611_18 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 368.0
TH2_k127_23611_19 Pfam Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 353.0
TH2_k127_23611_2 peptidase K01278,K18574 - 3.4.14.12,3.4.14.5 3.382e-230 732.0
TH2_k127_23611_20 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 353.0
TH2_k127_23611_21 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 341.0
TH2_k127_23611_22 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 329.0
TH2_k127_23611_23 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 314.0
TH2_k127_23611_24 synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 301.0
TH2_k127_23611_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 296.0
TH2_k127_23611_26 PFAM Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 304.0
TH2_k127_23611_27 Rhodanese Homology Domain K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 297.0
TH2_k127_23611_28 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005957 267.0
TH2_k127_23611_29 MORN repeat variant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002267 278.0
TH2_k127_23611_3 PFAM TonB-dependent Receptor Plug - - - 1.115e-214 692.0
TH2_k127_23611_30 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000002288 253.0
TH2_k127_23611_31 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000935 236.0
TH2_k127_23611_32 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000000000000000000000000000003014 211.0
TH2_k127_23611_33 DNA/RNA non-specific endonuclease K01173 - - 0.00000000000000000000000000000000000000000000000000000004163 207.0
TH2_k127_23611_34 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000000000000000000000000000001486 197.0
TH2_k127_23611_35 3-oxoacyl-(ACP) synthase - - - 0.000000000000000000000000000000000000000000000001684 180.0
TH2_k127_23611_36 Uncharacterized ACR, COG1678 K07735 - - 0.000000000000000000000000000000000000000000002006 170.0
TH2_k127_23611_37 Biotin lipoyl attachment domain-containing protein K01960 - 6.4.1.1 0.000000000000000000000000000000000000000000005738 169.0
TH2_k127_23611_38 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000001351 171.0
TH2_k127_23611_39 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000004968 181.0
TH2_k127_23611_4 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 3.748e-198 625.0
TH2_k127_23611_40 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000003129 156.0
TH2_k127_23611_41 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000008486 149.0
TH2_k127_23611_42 Belongs to the ArsC family K00537 - 1.20.4.1 0.000000000000000000000000000000007636 130.0
TH2_k127_23611_43 - - - - 0.0000000000000000000000000000001323 136.0
TH2_k127_23611_44 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000007462 117.0
TH2_k127_23611_45 - - - - 0.00000000000000000000000005109 110.0
TH2_k127_23611_46 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000005863 112.0
TH2_k127_23611_47 Domain of unknown function (DU1801) - - - 0.0000000000000000000005639 98.0
TH2_k127_23611_48 dehydratase K02372 - 4.2.1.59 0.000000000000000002762 89.0
TH2_k127_23611_49 Vitamin K-dependent gamma-carboxylase - - - 0.00000000000000001177 93.0
TH2_k127_23611_5 tryptophanase activity K01667 - 4.1.99.1 2.721e-194 616.0
TH2_k127_23611_50 Lysin motif - - - 0.00000000000005011 81.0
TH2_k127_23611_51 sub-family A member 2 K09502,K09503,K09505 GO:0001671,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008047,GO:0008150,GO:0008152,GO:0008284,GO:0009987,GO:0010033,GO:0018885,GO:0030234,GO:0032781,GO:0035966,GO:0042026,GO:0042127,GO:0042221,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051082,GO:0051087,GO:0051336,GO:0051345,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071704,GO:0098772 - 0.0000000000005984 79.0
TH2_k127_23611_52 - K05747,K20521 - - 0.000000000205 67.0
TH2_k127_23611_53 - - - - 0.000000002436 59.0
TH2_k127_23611_55 - - - - 0.00000001317 64.0
TH2_k127_23611_56 Pkd domain containing protein - - - 0.000001527 61.0
TH2_k127_23611_57 COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase - - - 0.000003017 58.0
TH2_k127_23611_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 613.0
TH2_k127_23611_7 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 587.0
TH2_k127_23611_8 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 547.0
TH2_k127_23611_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 472.0
TH2_k127_2452475_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 1.339e-245 764.0
TH2_k127_2452475_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 454.0
TH2_k127_2452475_10 Etoposide-induced protein 2.4 (EI24) K06203 - - 0.000000000000000000000000000000815 132.0
TH2_k127_2452475_11 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000002704 88.0
TH2_k127_2452475_12 Peptidyl-prolyl cis-trans isomerase K01802,K03767 - 5.2.1.8 0.000000000003384 76.0
TH2_k127_2452475_2 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 383.0
TH2_k127_2452475_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 349.0
TH2_k127_2452475_4 Protein of unknown function (DUF1456) - - - 0.000000000000000000000000000000000000000000000000000000000007804 210.0
TH2_k127_2452475_5 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000000000000000000006734 201.0
TH2_k127_2452475_6 Thiol peroxidase K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000001802 199.0
TH2_k127_2452475_7 PFAM Family of - - - 0.0000000000000000000000000000000000000002067 168.0
TH2_k127_2452475_8 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772 - 5.2.1.8 0.0000000000000000000000000000000000000005627 161.0
TH2_k127_2452475_9 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000001009 130.0
TH2_k127_2461575_0 PFAM Peptidase M1 membrane alanine aminopeptidase K01256 - 3.4.11.2 4.621e-215 698.0
TH2_k127_2461575_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 1.075e-202 636.0
TH2_k127_2461575_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 448.0
TH2_k127_2461575_3 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000421 278.0
TH2_k127_2461575_4 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000009988 153.0
TH2_k127_2461575_5 adhesin AidA-related - - - 0.0008517 51.0
TH2_k127_2488935_0 Response regulator of the LytR AlgR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 334.0
TH2_k127_2488935_1 metallopeptidase activity K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 301.0
TH2_k127_2488935_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000424 258.0
TH2_k127_2488935_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000851 169.0
TH2_k127_2621177_0 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 1.619e-289 922.0
TH2_k127_2621177_1 Psort location OuterMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 543.0
TH2_k127_2621177_10 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000112 276.0
TH2_k127_2621177_11 AsmA-like C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009131 281.0
TH2_k127_2621177_12 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000002314 270.0
TH2_k127_2621177_13 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000000000000000000000000006961 176.0
TH2_k127_2621177_14 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000003133 177.0
TH2_k127_2621177_15 PFAM phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000001554 175.0
TH2_k127_2621177_16 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000009555 170.0
TH2_k127_2621177_17 WG containing repeat - - - 0.00000000000000000000000000001024 135.0
TH2_k127_2621177_18 - - - - 0.0000000000000000000000000007829 118.0
TH2_k127_2621177_19 cellulose binding - - - 0.0000000000000000000001748 114.0
TH2_k127_2621177_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 468.0
TH2_k127_2621177_20 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000002921 96.0
TH2_k127_2621177_21 Redoxin - - - 0.000000000000000000145 94.0
TH2_k127_2621177_22 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000933 94.0
TH2_k127_2621177_23 Protein conserved in bacteria - - - 0.000000000000002548 81.0
TH2_k127_2621177_24 Belongs to the peptidase S8 family - - - 0.000000000000007035 87.0
TH2_k127_2621177_26 Domain of unknown function (DUF4783) - - - 0.000000000004849 70.0
TH2_k127_2621177_27 regulation of DNA-templated transcription, elongation - - - 0.00000001294 62.0
TH2_k127_2621177_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 442.0
TH2_k127_2621177_4 ABC-type uncharacterized transport system K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 445.0
TH2_k127_2621177_5 fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 391.0
TH2_k127_2621177_6 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 329.0
TH2_k127_2621177_7 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 321.0
TH2_k127_2621177_8 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 303.0
TH2_k127_2621177_9 TIGRFAM gliding motility-associated ABC transporter permease protein GldF K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 299.0
TH2_k127_2782528_0 glutamine synthetase K01915 - 6.3.1.2 0.0 1022.0
TH2_k127_2782528_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.843e-212 680.0
TH2_k127_2782528_2 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 541.0
TH2_k127_2782528_3 37-kD nucleoid-associated bacterial protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 329.0
TH2_k127_2782528_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000003971 165.0
TH2_k127_2782528_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000001497 152.0
TH2_k127_2782528_6 metallopeptidase activity - - - 0.000000000000000000000000000000000000005274 157.0
TH2_k127_2782528_7 SWIB/MDM2 domain K03169 - 5.99.1.2 0.000000000000000000000000000000000000007324 148.0
TH2_k127_2782528_8 - - - - 0.00000000000000000000000000000111 131.0
TH2_k127_2782528_9 PKD domain containing protein - - - 0.000000000000000000000000000003043 133.0
TH2_k127_2786664_0 CarboxypepD_reg-like domain - - - 1.637e-200 651.0
TH2_k127_2786664_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 616.0
TH2_k127_2786664_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 550.0
TH2_k127_2786664_3 Pectate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 617.0
TH2_k127_2786664_4 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 444.0
TH2_k127_2786664_5 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 326.0
TH2_k127_2786664_6 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001356 276.0
TH2_k127_2786664_7 Eukaryotic integral membrane protein (DUF1751) K09650 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000000000000000000303 253.0
TH2_k127_2786664_8 Rhomboid family - - - 0.000000000000000000000000000000000000001923 157.0
TH2_k127_2787264_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.195e-220 697.0
TH2_k127_2787264_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 566.0
TH2_k127_2787264_2 C-terminal domain of CHU protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 360.0
TH2_k127_2787264_3 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 324.0
TH2_k127_2849268_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0 1063.0
TH2_k127_2849268_1 glucose-1-phosphate thymidylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 428.0
TH2_k127_2849268_10 Hep Hag repeat protein - - - 0.000000000000000000000000002289 129.0
TH2_k127_2849268_11 Hep Hag repeat protein - - - 0.000000000000000000000000002392 130.0
TH2_k127_2849268_12 Hep Hag repeat protein - - - 0.00000000000000000000000001041 128.0
TH2_k127_2849268_13 protein secretion K21449 - - 0.000000000000000000000002671 120.0
TH2_k127_2849268_14 Pkd domain containing protein - - - 0.0000000000000000005078 99.0
TH2_k127_2849268_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000001345 75.0
TH2_k127_2849268_16 - - - - 0.0000000004153 73.0
TH2_k127_2849268_17 Chaperone of endosialidase K21449 - - 0.0000003787 64.0
TH2_k127_2849268_18 Outer membrane protein (OmpH-like) K06142 - - 0.0000006313 59.0
TH2_k127_2849268_19 COG3209 Rhs family protein - - - 0.00001806 58.0
TH2_k127_2849268_2 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004927 304.0
TH2_k127_2849268_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000004216 228.0
TH2_k127_2849268_4 membrane - - - 0.00000000000000000000000000000000000000000000000000004756 198.0
TH2_k127_2849268_5 Phosphoribosyl-ATP pyrophosphohydrolase - - - 0.000000000000000000000000000000000000000000000001172 177.0
TH2_k127_2849268_6 domain, Protein K08961 - 4.2.2.20,4.2.2.21 0.00000000000000000000000000000000000000001235 178.0
TH2_k127_2849268_7 PFAM NlpC P60 family K13694,K13695 - 3.4.17.13 0.0000000000000000000000000000000000002273 147.0
TH2_k127_2849268_8 - - - - 0.00000000000000000000000000000000018 146.0
TH2_k127_2849268_9 Hep Hag repeat protein - - - 0.0000000000000000000000000009887 131.0
TH2_k127_2868931_0 SprB repeat - - - 0.0 1252.0
TH2_k127_2868931_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0 1227.0
TH2_k127_2868931_10 peptidase M42 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 578.0
TH2_k127_2868931_11 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 578.0
TH2_k127_2868931_12 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 577.0
TH2_k127_2868931_13 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K01817 - 4.2.1.20,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 561.0
TH2_k127_2868931_14 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 487.0
TH2_k127_2868931_15 Cytochrome C4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 470.0
TH2_k127_2868931_16 Rhodanase C-terminal K07146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 432.0
TH2_k127_2868931_17 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 411.0
TH2_k127_2868931_18 peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 385.0
TH2_k127_2868931_19 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 354.0
TH2_k127_2868931_2 MMPL family K07003 - - 0.0 1151.0
TH2_k127_2868931_20 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 354.0
TH2_k127_2868931_21 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 347.0
TH2_k127_2868931_22 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 355.0
TH2_k127_2868931_23 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 342.0
TH2_k127_2868931_24 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 321.0
TH2_k127_2868931_25 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 318.0
TH2_k127_2868931_26 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 313.0
TH2_k127_2868931_27 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 307.0
TH2_k127_2868931_28 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 304.0
TH2_k127_2868931_29 Bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 305.0
TH2_k127_2868931_3 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 8.796e-244 774.0
TH2_k127_2868931_30 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 299.0
TH2_k127_2868931_31 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002237 272.0
TH2_k127_2868931_32 Anthranilate synthase subunit II K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002668 269.0
TH2_k127_2868931_33 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000006499 261.0
TH2_k127_2868931_34 Aldose 1-epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001111 263.0
TH2_k127_2868931_35 translation initiation factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001613 243.0
TH2_k127_2868931_36 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K01227 - 3.2.1.96 0.00000000000000000000000000000000000000000000000000000000000000000002539 245.0
TH2_k127_2868931_37 Bacterial Ig-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001566 241.0
TH2_k127_2868931_38 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006625 223.0
TH2_k127_2868931_39 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.000000000000000000000000000000000000000000000000000000000000102 233.0
TH2_k127_2868931_4 Homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 4.882e-235 728.0
TH2_k127_2868931_40 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000000000000000000000000000000000003071 224.0
TH2_k127_2868931_41 Stage II sporulation protein E (SpoIIE) - - - 0.0000000000000000000000000000000000000000000000000000000001204 218.0
TH2_k127_2868931_42 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000001424 210.0
TH2_k127_2868931_43 TIGRFAM 6-pyruvoyl tetrahydropterin synthase QueD family protein K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000001428 199.0
TH2_k127_2868931_44 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.00000000000000000000000000000000000000000000000000003214 194.0
TH2_k127_2868931_45 acetyltransferase K22441 - 2.3.1.57 0.0000000000000000000000000000000000000000000008138 171.0
TH2_k127_2868931_46 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000008325 166.0
TH2_k127_2868931_47 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000000000002061 142.0
TH2_k127_2868931_48 PFAM PKD domain - - - 0.0000000000000000000000000000002006 146.0
TH2_k127_2868931_49 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000000000000000005662 119.0
TH2_k127_2868931_5 COG0826 Collagenase and related K08303 - - 2.545e-203 639.0
TH2_k127_2868931_50 Gliding motility-associated protein GldC - - - 0.00000000000000000000000000001973 120.0
TH2_k127_2868931_51 COG2346, Truncated hemoglobins K06886 - - 0.00000000000000000000000004027 111.0
TH2_k127_2868931_52 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000002233 104.0
TH2_k127_2868931_53 Protein of unknown function (DUF493) K09158 - - 0.00000000000000003882 83.0
TH2_k127_2868931_54 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.000000000000002398 87.0
TH2_k127_2868931_55 Protein of unknown function (DUF1569) - - - 0.000000000001581 73.0
TH2_k127_2868931_56 Outer membrane protein beta-barrel domain - - - 0.0000000005315 70.0
TH2_k127_2868931_57 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000001894 53.0
TH2_k127_2868931_58 - - - - 0.000002213 55.0
TH2_k127_2868931_59 cellulase activity K01183,K01728 - 3.2.1.14,4.2.2.2 0.00001848 60.0
TH2_k127_2868931_6 GH3 auxin-responsive promoter - - - 9.179e-199 631.0
TH2_k127_2868931_60 Metallo-peptidase family M12B Reprolysin-like - - - 0.00006917 55.0
TH2_k127_2868931_7 regulator - - - 1.809e-196 650.0
TH2_k127_2868931_8 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 614.0
TH2_k127_2868931_9 peptidase activity, acting on L-amino acid peptides K05996 - 3.4.17.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 627.0
TH2_k127_3045017_0 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009022 602.0
TH2_k127_3045017_1 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 324.0
TH2_k127_3045017_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001311 285.0
TH2_k127_3045017_3 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000001164 250.0
TH2_k127_3120250_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1165.0
TH2_k127_3120250_1 Angiotensin-converting enzyme K01283 - 3.4.15.1 7.524e-250 784.0
TH2_k127_3120250_10 NEDD4-binding protein 2-like 1 - - - 0.00000001415 57.0
TH2_k127_3120250_2 Participates in initiation and elongation during chromosome replication - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 608.0
TH2_k127_3120250_3 regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 458.0
TH2_k127_3120250_4 PFAM Squalene phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 375.0
TH2_k127_3120250_5 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 328.0
TH2_k127_3120250_6 PFAM MerR family regulatory protein K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 289.0
TH2_k127_3120250_7 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000002463 209.0
TH2_k127_3120250_8 Beta-carotene hydroxylase K15746 - 1.14.15.24 0.0000000000000000000000000000000000000000000000000000009163 196.0
TH2_k127_3120250_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000005148 149.0
TH2_k127_3280977_0 PFAM Type III restriction enzyme, res subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 589.0
TH2_k127_3280977_1 PFAM Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 390.0
TH2_k127_3280977_2 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000001195 184.0
TH2_k127_3280977_3 regulation of response to stimulus - - - 0.0000000000000000000001853 103.0
TH2_k127_3314245_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1151.0
TH2_k127_3314245_1 SecY translocase K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 602.0
TH2_k127_3314245_10 Pfam:Arch_ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 306.0
TH2_k127_3314245_11 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 288.0
TH2_k127_3314245_12 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005012 275.0
TH2_k127_3314245_13 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001423 271.0
TH2_k127_3314245_14 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002305 262.0
TH2_k127_3314245_15 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000008689 244.0
TH2_k127_3314245_16 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000006724 236.0
TH2_k127_3314245_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000004633 224.0
TH2_k127_3314245_18 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001213 223.0
TH2_k127_3314245_19 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000006482 217.0
TH2_k127_3314245_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 529.0
TH2_k127_3314245_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000001138 226.0
TH2_k127_3314245_21 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003572 213.0
TH2_k127_3314245_22 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000003949 198.0
TH2_k127_3314245_23 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000004062 196.0
TH2_k127_3314245_24 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000004836 197.0
TH2_k127_3314245_25 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000002252 185.0
TH2_k127_3314245_26 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000008936 185.0
TH2_k127_3314245_27 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000002356 163.0
TH2_k127_3314245_28 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000001675 145.0
TH2_k127_3314245_29 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002777 141.0
TH2_k127_3314245_3 chitinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 535.0
TH2_k127_3314245_30 Ribosomal protein S14p/S29e K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001641 139.0
TH2_k127_3314245_31 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000125 133.0
TH2_k127_3314245_32 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000002258 126.0
TH2_k127_3314245_33 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000006875 123.0
TH2_k127_3314245_34 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000009211 111.0
TH2_k127_3314245_35 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000002624 69.0
TH2_k127_3314245_36 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000001 64.0
TH2_k127_3314245_37 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000007086 61.0
TH2_k127_3314245_38 PFAM blue (type 1) copper domain protein - - - 0.00006875 55.0
TH2_k127_3314245_4 usher protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 426.0
TH2_k127_3314245_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 407.0
TH2_k127_3314245_6 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 376.0
TH2_k127_3314245_7 SPTR Fibronectin type III domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 347.0
TH2_k127_3314245_8 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 315.0
TH2_k127_3314245_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 307.0
TH2_k127_33228_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 511.0
TH2_k127_33228_1 Protein of unknown function (DUF1698) - - - 0.00000000000000000000000000000000000000000000000000000001796 204.0
TH2_k127_33228_2 COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein K03640 - - 0.00000000000000000000000000000002176 141.0
TH2_k127_33228_3 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.0000000000000000000000007732 105.0
TH2_k127_33228_4 GIY-YIG catalytic domain protein K07461 - - 0.00000000000000000000001626 104.0
TH2_k127_33228_5 Cold shock K03704 - - 0.000000000000000000009675 93.0
TH2_k127_3366624_0 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 453.0
TH2_k127_3366624_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 297.0
TH2_k127_3366624_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000002032 161.0
TH2_k127_3366624_4 muconolactone delta-isomerase - - - 0.00000000005356 66.0
TH2_k127_3385260_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1234.0
TH2_k127_3385260_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.944e-207 651.0
TH2_k127_3385260_10 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 353.0
TH2_k127_3385260_11 KR domain K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 328.0
TH2_k127_3385260_12 Belongs to the peptidase S8 family K07004,K20755 - 3.4.21.121 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 318.0
TH2_k127_3385260_13 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001873 285.0
TH2_k127_3385260_14 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003 260.0
TH2_k127_3385260_15 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002578 252.0
TH2_k127_3385260_16 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000004481 219.0
TH2_k127_3385260_17 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000001402 202.0
TH2_k127_3385260_18 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00000000000000000000000000000000002883 139.0
TH2_k127_3385260_19 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000000000001585 137.0
TH2_k127_3385260_2 Histidine ammonia-lyase K01745,K10774 - 4.3.1.23,4.3.1.3 1.222e-205 653.0
TH2_k127_3385260_20 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000005428 123.0
TH2_k127_3385260_21 amine dehydrogenase activity - - - 0.00000002875 66.0
TH2_k127_3385260_22 WD-40 repeat - - - 0.00001349 57.0
TH2_k127_3385260_3 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 597.0
TH2_k127_3385260_4 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 571.0
TH2_k127_3385260_5 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 550.0
TH2_k127_3385260_6 PFAM PKD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 487.0
TH2_k127_3385260_7 PFAM FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 430.0
TH2_k127_3385260_8 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 387.0
TH2_k127_3385260_9 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 374.0
TH2_k127_340037_0 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 487.0
TH2_k127_340037_1 chorismate mutase K04516 - 5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 438.0
TH2_k127_340037_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001651 253.0
TH2_k127_340037_11 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000004167 227.0
TH2_k127_340037_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000005638 205.0
TH2_k127_340037_13 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000001819 197.0
TH2_k127_340037_14 - - - - 0.0000000000000000000000002351 118.0
TH2_k127_340037_15 metallopeptidase activity - - - 0.0000000000000000002317 101.0
TH2_k127_340037_16 Pkd domain containing protein K01179 - 3.2.1.4 0.00000000000001281 86.0
TH2_k127_340037_17 - - - - 0.00000003922 61.0
TH2_k127_340037_2 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 445.0
TH2_k127_340037_3 Dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 417.0
TH2_k127_340037_4 aspartate--ammonia ligase K01914 - 6.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 389.0
TH2_k127_340037_5 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 361.0
TH2_k127_340037_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 355.0
TH2_k127_340037_7 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 335.0
TH2_k127_340037_8 TIGRFAM TIGR02757 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 326.0
TH2_k127_340037_9 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 342.0
TH2_k127_3426436_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639,K20967 - 4.1.99.22,4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 405.0
TH2_k127_3426436_1 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 340.0
TH2_k127_3426436_11 Pfam:Pyridox_oxidase K09979 - - 0.000000000000000000000000002513 116.0
TH2_k127_3426436_12 - - - - 0.0000000000000000000000008682 113.0
TH2_k127_3426436_13 GIY-YIG catalytic domain protein K07461 - - 0.000000000608 61.0
TH2_k127_3426436_2 Transporter K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 314.0
TH2_k127_3426436_3 cytochrome C peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 299.0
TH2_k127_3426436_4 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002957 294.0
TH2_k127_3426436_6 Domain of unknown function (DUF4114) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006903 259.0
TH2_k127_3426436_7 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000004122 166.0
TH2_k127_3426436_8 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - 0.00000000000000000000000000000000000005759 152.0
TH2_k127_3426436_9 Domain of Unknown function (DUF542) K07322 - - 0.00000000000000000000000000000000002943 143.0
TH2_k127_3455693_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.314e-207 656.0
TH2_k127_3455693_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 4.697e-204 644.0
TH2_k127_3455693_2 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 555.0
TH2_k127_3455693_3 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 480.0
TH2_k127_3455693_4 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001169 237.0
TH2_k127_3455693_5 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000000000000000000000005394 205.0
TH2_k127_3455693_6 ATPase kinase involved in NAD metabolism - - - 0.00000000000000000000000000000000009485 140.0
TH2_k127_3455693_7 TIGRFAM nicotinamide mononucleotide transporter PnuC K03811 - - 0.0000000000000000000000001029 114.0
TH2_k127_3455693_8 - - - - 0.000000000000000000000003927 108.0
TH2_k127_3455693_9 Cytochrome P460 - - - 0.00041 49.0
TH2_k127_3524589_0 Peptide-N-glycosidase F, C terminal - - - 0.0 1094.0
TH2_k127_3524589_1 Methylcrotonoyl-CoA carboxylase - - - 1.551e-288 893.0
TH2_k127_3524589_10 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 557.0
TH2_k127_3524589_11 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 535.0
TH2_k127_3524589_12 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 511.0
TH2_k127_3524589_13 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 428.0
TH2_k127_3524589_14 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 395.0
TH2_k127_3524589_15 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 398.0
TH2_k127_3524589_16 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 368.0
TH2_k127_3524589_17 Alg9-like mannosyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 370.0
TH2_k127_3524589_18 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 309.0
TH2_k127_3524589_19 Major intrinsic protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 300.0
TH2_k127_3524589_2 TonB-dependent receptor - - - 1.181e-232 745.0
TH2_k127_3524589_20 Permease, YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 302.0
TH2_k127_3524589_21 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 290.0
TH2_k127_3524589_22 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 297.0
TH2_k127_3524589_23 Protein tyrosine phosphatase K01104,K03741 - 1.20.4.1,3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000191 285.0
TH2_k127_3524589_24 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004179 269.0
TH2_k127_3524589_25 PFAM Fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000001342 249.0
TH2_k127_3524589_26 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000002834 237.0
TH2_k127_3524589_27 PhnA protein K06193 - - 0.000000000000000000000000000000000000000000000000000000000000000008771 229.0
TH2_k127_3524589_28 penicillin-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000009519 232.0
TH2_k127_3524589_29 Protein of unknown function (DUF3078) - - - 0.0000000000000000000000000000000000000000000000000000000000000385 225.0
TH2_k127_3524589_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 1.717e-200 628.0
TH2_k127_3524589_30 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838,K19270 GO:0000287,GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050084,GO:0050286,GO:0050308,GO:0050309 3.1.3.23,5.4.2.6 0.00000000000000000000000000000000000000000000000000000000002559 212.0
TH2_k127_3524589_31 - - - - 0.00000000000000000000000000000000000000000000000000000008506 200.0
TH2_k127_3524589_32 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000003722 199.0
TH2_k127_3524589_33 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000002449 205.0
TH2_k127_3524589_34 - - - - 0.0000000000000000000000000000000000000000000000000000264 206.0
TH2_k127_3524589_35 Domain of unknown function (DUF1987) - - - 0.000000000000000000000000000000000000000000000000009866 183.0
TH2_k127_3524589_36 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000002268 180.0
TH2_k127_3524589_37 - - - - 0.0000000000000000000000000000000000000000000003981 174.0
TH2_k127_3524589_38 MORN repeat variant - - - 0.0000000000000000000000000000000000000001387 160.0
TH2_k127_3524589_39 anaphase-promoting complex binding - - - 0.00000000000000000000000000001862 135.0
TH2_k127_3524589_4 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 596.0
TH2_k127_3524589_41 - - - - 0.00000000001811 66.0
TH2_k127_3524589_42 - - - - 0.0000000002861 71.0
TH2_k127_3524589_43 - - - - 0.000000001211 60.0
TH2_k127_3524589_44 Endonuclease I - - - 0.00000003393 57.0
TH2_k127_3524589_45 Pfam:Arch_ATPase - - - 0.000001301 50.0
TH2_k127_3524589_46 Pkd domain containing protein - - - 0.0003029 53.0
TH2_k127_3524589_47 - K12287 - - 0.0009288 51.0
TH2_k127_3524589_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 581.0
TH2_k127_3524589_6 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 572.0
TH2_k127_3524589_7 RecQ zinc-binding K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 585.0
TH2_k127_3524589_8 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 604.0
TH2_k127_3524589_9 Aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 569.0
TH2_k127_3549307_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1151.0
TH2_k127_3557669_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1208.0
TH2_k127_3557669_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 548.0
TH2_k127_3557669_10 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 352.0
TH2_k127_3557669_11 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 355.0
TH2_k127_3557669_12 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 340.0
TH2_k127_3557669_13 ATPase histidine kinase DNA gyrase B HSP90 domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 304.0
TH2_k127_3557669_14 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000002595 215.0
TH2_k127_3557669_15 RNA methyltransferase TrmH K03437 - - 0.0000000000000000000000000000000000000000000000000000002002 202.0
TH2_k127_3557669_16 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000008774 190.0
TH2_k127_3557669_17 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000000001753 159.0
TH2_k127_3557669_18 PAP2 superfamily K19302 - 3.6.1.27 0.00000000000000000000000000000000000000139 154.0
TH2_k127_3557669_19 - - - - 0.0000000000000000000000000000000004822 137.0
TH2_k127_3557669_2 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 - 1.14.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 542.0
TH2_k127_3557669_20 Protein of unknown function (DUF1573) - - - 0.0000000000000000000000000000000005595 135.0
TH2_k127_3557669_21 Protein of unknown function (DUF1573) - - - 0.000000000000000000000000000000008974 134.0
TH2_k127_3557669_22 - - - - 0.000000000000000000000000000002771 121.0
TH2_k127_3557669_23 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000109 127.0
TH2_k127_3557669_24 OmpA family - - - 0.0000000000000000000000000002607 118.0
TH2_k127_3557669_25 Protein of unknown function (DUF1573) - - - 0.00000000000000006304 86.0
TH2_k127_3557669_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 451.0
TH2_k127_3557669_4 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 432.0
TH2_k127_3557669_5 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 430.0
TH2_k127_3557669_6 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009894 408.0
TH2_k127_3557669_7 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 429.0
TH2_k127_3557669_8 Beta-lactamase superfamily domain K06136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 383.0
TH2_k127_3557669_9 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 378.0
TH2_k127_3612941_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1228.0
TH2_k127_3612941_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 592.0
TH2_k127_3612941_10 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000001242 194.0
TH2_k127_3612941_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000004992 164.0
TH2_k127_3612941_12 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000007624 168.0
TH2_k127_3612941_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 518.0
TH2_k127_3612941_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 398.0
TH2_k127_3612941_4 endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 304.0
TH2_k127_3612941_5 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002036 269.0
TH2_k127_3612941_6 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001628 231.0
TH2_k127_3612941_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001635 221.0
TH2_k127_3612941_8 phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000001755 209.0
TH2_k127_3612941_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000003594 205.0
TH2_k127_3621019_0 DNA polymerase alpha chain like domain K02337 - 2.7.7.7 0.0 1636.0
TH2_k127_3621019_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type K00615 - 2.2.1.1 0.0 1063.0
TH2_k127_3621019_10 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 473.0
TH2_k127_3621019_11 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 466.0
TH2_k127_3621019_12 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 411.0
TH2_k127_3621019_13 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 426.0
TH2_k127_3621019_14 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 390.0
TH2_k127_3621019_15 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 389.0
TH2_k127_3621019_16 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 353.0
TH2_k127_3621019_17 thiolester hydrolase activity K06889 GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 339.0
TH2_k127_3621019_18 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 334.0
TH2_k127_3621019_19 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004527 273.0
TH2_k127_3621019_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 2.885e-254 794.0
TH2_k127_3621019_20 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000002158 232.0
TH2_k127_3621019_21 gliding motility-associated C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000005232 237.0
TH2_k127_3621019_22 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000002777 228.0
TH2_k127_3621019_23 Biogenesis protein - - - 0.000000000000000000000000000000000000000000000000000000002008 206.0
TH2_k127_3621019_24 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000000001944 193.0
TH2_k127_3621019_25 WbqC-like protein family - - - 0.000000000000000000000000000000000000000000000001663 180.0
TH2_k127_3621019_26 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K20446 - 1.17.1.5,1.2.5.3 0.000000000000000000000000000000000000000000000005403 177.0
TH2_k127_3621019_27 Protein of unknown function (DUF1761) - - - 0.000000000000000000000000000000000000000000000005575 177.0
TH2_k127_3621019_28 Lysin motif - - - 0.0000000000000000000000000000000000000000000009937 177.0
TH2_k127_3621019_29 Bacterial PH domain K08981 - - 0.00000000000000000000000000000000000000000001248 168.0
TH2_k127_3621019_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.25e-244 777.0
TH2_k127_3621019_30 Ribosomal protein L31 K02909 - - 0.000000000000000000000000000000000000002895 148.0
TH2_k127_3621019_31 CarboxypepD_reg-like domain - - - 0.00000000000000000000000000000000000002762 152.0
TH2_k127_3621019_32 pfam nudix - - - 0.000000000000000000000000000000000000124 145.0
TH2_k127_3621019_33 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.000000000000000000000000000000003075 132.0
TH2_k127_3621019_34 CO dehydrogenase flavoprotein C-terminal domain K13479 - 1.17.1.4 0.000000000000000000000000000000005057 139.0
TH2_k127_3621019_35 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000001088 138.0
TH2_k127_3621019_36 Hydroxymethylglutaryl-coenzyme A synthase N terminal K01641,K15311 - 2.3.3.10 0.000000000000000000000002028 117.0
TH2_k127_3621019_37 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.00000000000000000000007801 105.0
TH2_k127_3621019_38 Domain of unknown function (DUF4293) - - - 0.000000000435 66.0
TH2_k127_3621019_4 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 4.354e-230 733.0
TH2_k127_3621019_5 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly - - - 5.067e-225 709.0
TH2_k127_3621019_6 PFAM Enoyl-CoA hydratase isomerase - - - 7.957e-216 689.0
TH2_k127_3621019_7 Selenocysteine lyase - - - 1.887e-215 680.0
TH2_k127_3621019_8 Fungalysin/Thermolysin Propeptide Motif K01400 - 3.4.24.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 542.0
TH2_k127_3621019_9 Fungalysin/Thermolysin Propeptide Motif K01400 - 3.4.24.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 529.0
TH2_k127_3719714_0 Motility related/secretion protein - - - 0.0 1876.0
TH2_k127_3719714_1 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 0.0 1034.0
TH2_k127_3719714_10 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 316.0
TH2_k127_3719714_11 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 295.0
TH2_k127_3719714_12 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 295.0
TH2_k127_3719714_13 regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008424 275.0
TH2_k127_3719714_14 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002708 260.0
TH2_k127_3719714_15 Iron-storage protein K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000000000000000000004043 224.0
TH2_k127_3719714_16 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0000000000000000000000000000000000000000000000000000000000001922 232.0
TH2_k127_3719714_17 COG1680 Beta-lactamase class C and other penicillin binding K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000005467 225.0
TH2_k127_3719714_18 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000000000000000005895 205.0
TH2_k127_3719714_19 Glycine cleavage H-protein K02437 - - 0.00000000000000000000000000000000000000000000000000000001784 199.0
TH2_k127_3719714_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 5.13e-199 629.0
TH2_k127_3719714_20 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000003816 196.0
TH2_k127_3719714_21 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000009869 180.0
TH2_k127_3719714_22 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000001991 169.0
TH2_k127_3719714_23 2',5' RNA ligase - - - 0.0000000000000000000000000000000000000003726 154.0
TH2_k127_3719714_24 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.000000000000000000000000004353 114.0
TH2_k127_3719714_25 Septum formation initiator - - - 0.0000000000000000000001166 100.0
TH2_k127_3719714_26 excinuclease ABC K07461 - - 0.0000000000000000002554 91.0
TH2_k127_3719714_27 YceI-like domain - - - 0.0000000000001169 81.0
TH2_k127_3719714_28 VanZ like family - - - 0.0000000002456 66.0
TH2_k127_3719714_3 PIN domain K07175 - - 5.393e-195 617.0
TH2_k127_3719714_4 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 586.0
TH2_k127_3719714_5 COG4206 Outer membrane cobalamin receptor protein K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 505.0
TH2_k127_3719714_6 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 466.0
TH2_k127_3719714_7 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 385.0
TH2_k127_3719714_8 ATPases associated with a variety of cellular activities K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 331.0
TH2_k127_3719714_9 COG2812 DNA polymerase III gamma tau subunits K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 329.0
TH2_k127_372273_0 Peptidase family C25 - - - 6.958e-269 876.0
TH2_k127_372273_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.277e-266 825.0
TH2_k127_372273_10 Sigma factor PP2C-like phosphatases K02660,K07315,K17763,K20971,K21009 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000007568 288.0
TH2_k127_372273_11 Type IX secretion system membrane protein PorP/SprF - - - 0.000000000000000000000000000000000000000000002881 177.0
TH2_k127_372273_12 metallopeptidase activity K01337 - 3.4.21.50 0.0000000000000000000000000000000000000006553 158.0
TH2_k127_372273_13 DNA-binding protein - - - 0.0000000000000000000000000000000001876 134.0
TH2_k127_372273_14 - - - - 0.00000000000000000000000000003528 135.0
TH2_k127_372273_15 - - - - 0.0000000000000000000000001246 124.0
TH2_k127_372273_16 regulation of response to stimulus K13730 - - 0.000000000000000000007931 100.0
TH2_k127_372273_17 PFAM ATP synthase, Delta Epsilon chain, beta-sandwich domain K02114 - - 0.00000000000000000002984 92.0
TH2_k127_372273_2 acyl-CoA dehydrogenase K00252 - 1.3.8.6 9.467e-219 683.0
TH2_k127_372273_3 Psort location OuterMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 376.0
TH2_k127_372273_4 OmpA MotB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 383.0
TH2_k127_372273_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 326.0
TH2_k127_372273_6 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 316.0
TH2_k127_372273_7 Type IX secretion system membrane protein PorP/SprF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 289.0
TH2_k127_372273_8 DNA catabolic process, exonucleolytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002355 295.0
TH2_k127_372273_9 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003122 287.0
TH2_k127_3734704_0 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000009483 161.0
TH2_k127_3734704_2 - - - - 0.00003974 51.0
TH2_k127_3767729_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 492.0
TH2_k127_3767729_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 483.0
TH2_k127_3767729_10 Biopolymer transporter ExbD - - - 0.00000000000000000000000000000000000000000004743 168.0
TH2_k127_3767729_11 Biopolymer transporter ExbD - - - 0.00000000000000000000000000000000000000002173 160.0
TH2_k127_3767729_12 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000007918 145.0
TH2_k127_3767729_13 acr, cog1399 - - - 0.00000000000000000000000001452 115.0
TH2_k127_3767729_14 - - - - 0.00000000000000000000000001698 117.0
TH2_k127_3767729_15 Ribosomal L32p protein family K02911 - - 0.000000000000000000005015 93.0
TH2_k127_3767729_16 C-terminal domain of CHU protein family - - - 0.000000000000000831 92.0
TH2_k127_3767729_17 protein related to plant photosystem II stability assembly factor - - - 0.000000009622 67.0
TH2_k127_3767729_18 chlorophyll binding - - - 0.0004041 52.0
TH2_k127_3767729_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 479.0
TH2_k127_3767729_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 422.0
TH2_k127_3767729_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 384.0
TH2_k127_3767729_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 326.0
TH2_k127_3767729_6 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 289.0
TH2_k127_3767729_7 Bacterial toxin 23 - - - 0.000000000000000000000000000000000000000000000000000000000005576 218.0
TH2_k127_3767729_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000000000000000861 196.0
TH2_k127_3767729_9 YjbR - - - 0.00000000000000000000000000000000000000000001538 168.0
TH2_k127_3844077_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1355.0
TH2_k127_3844077_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 3.646e-276 871.0
TH2_k127_3844077_10 Chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 497.0
TH2_k127_3844077_11 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 463.0
TH2_k127_3844077_12 DEAD DEAH box helicase K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 464.0
TH2_k127_3844077_13 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008527 444.0
TH2_k127_3844077_14 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 416.0
TH2_k127_3844077_15 TonB-dependent receptor K02014,K16087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 400.0
TH2_k127_3844077_16 C-terminal domain of CHU protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 400.0
TH2_k127_3844077_17 D-isomer specific 2-hydroxyacid dehydrogenase K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 393.0
TH2_k127_3844077_18 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K08314 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 372.0
TH2_k127_3844077_19 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009974 336.0
TH2_k127_3844077_2 COG4206 Outer membrane cobalamin receptor protein K02014 - - 7.663e-226 724.0
TH2_k127_3844077_20 Response regulator of the LytR AlgR family K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 323.0
TH2_k127_3844077_21 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 301.0
TH2_k127_3844077_22 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002164 278.0
TH2_k127_3844077_23 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008552 273.0
TH2_k127_3844077_24 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000001821 250.0
TH2_k127_3844077_25 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001955 260.0
TH2_k127_3844077_26 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000001661 251.0
TH2_k127_3844077_27 Pkd domain containing protein K01337 - 3.4.21.50 0.0000000000000000000000000000000000000000000000000000000000000000000006038 265.0
TH2_k127_3844077_28 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007887 246.0
TH2_k127_3844077_29 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001027 240.0
TH2_k127_3844077_3 peptidase M1 K01256 - 3.4.11.2 1.781e-215 705.0
TH2_k127_3844077_30 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000001023 252.0
TH2_k127_3844077_31 Domain of unknown function (DUF4369) - - - 0.000000000000000000000000000000000000000000000000000000000000000002315 240.0
TH2_k127_3844077_32 - - - - 0.00000000000000000000000000000000000000000000000000000000000000576 219.0
TH2_k127_3844077_33 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000001728 220.0
TH2_k127_3844077_34 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000002287 208.0
TH2_k127_3844077_35 transcription activator, effector binding K13653 - - 0.000000000000000000000000000000000000000000000000001409 187.0
TH2_k127_3844077_36 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000001041 181.0
TH2_k127_3844077_37 EamA-like transporter family - - - 0.00000000000000000000000000000000008048 145.0
TH2_k127_3844077_38 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.0000000000000000000000000000000001878 138.0
TH2_k127_3844077_39 - - - - 0.0000000000000003043 85.0
TH2_k127_3844077_4 Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) K00209 - 1.3.1.44,1.3.1.9 8.806e-206 645.0
TH2_k127_3844077_40 - - - - 0.0000000000000003313 90.0
TH2_k127_3844077_41 - - - - 0.000000000000001316 78.0
TH2_k127_3844077_42 PFAM KWG Leptospira repeat protein - - - 0.000000000003081 77.0
TH2_k127_3844077_44 CsbD-like - - - 0.000000000009057 67.0
TH2_k127_3844077_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 7.556e-202 639.0
TH2_k127_3844077_6 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 577.0
TH2_k127_3844077_7 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 585.0
TH2_k127_3844077_8 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 527.0
TH2_k127_3844077_9 PFAM Glycosyl transferases group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 492.0
TH2_k127_386053_0 peptidase K01278 - 3.4.14.5 9.731e-253 799.0
TH2_k127_386053_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 3.203e-218 683.0
TH2_k127_386053_10 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000006072 192.0
TH2_k127_386053_11 Response regulator of the LytR AlgR family K02477 - - 0.0000000000000000000000000000000000000000000000000006954 192.0
TH2_k127_386053_12 thioesterase K07107 - - 0.00000000000000000000000000000000000000000002868 164.0
TH2_k127_386053_13 metallopeptidase activity - - - 0.00000000000000000000000000000000005 146.0
TH2_k127_386053_14 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.00000000000000000000000000000001133 136.0
TH2_k127_386053_15 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000003415 101.0
TH2_k127_386053_16 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000001734 97.0
TH2_k127_386053_17 - - - - 0.000001305 57.0
TH2_k127_386053_2 lysine biosynthetic process via aminoadipic acid - - - 2.252e-206 665.0
TH2_k127_386053_3 PFAM NAD dependent epimerase dehydratase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 588.0
TH2_k127_386053_4 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 538.0
TH2_k127_386053_5 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 318.0
TH2_k127_386053_6 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 326.0
TH2_k127_386053_7 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001309 280.0
TH2_k127_386053_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000781 236.0
TH2_k127_386053_9 PFAM Signal transduction histidine kinase, internal region - - - 0.0000000000000000000000000000000000000000000000000000000000001921 241.0
TH2_k127_4041926_0 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 529.0
TH2_k127_4041926_1 TamB, inner membrane protein subunit of TAM complex - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 510.0
TH2_k127_407592_0 Di- and tricarboxylate transporters K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 395.0
TH2_k127_407592_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 380.0
TH2_k127_407592_2 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 305.0
TH2_k127_407653_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 534.0
TH2_k127_407653_1 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000004232 252.0
TH2_k127_407653_2 PFAM EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002581 245.0
TH2_k127_4189886_0 PFAM Carbamoyl-phosphate synthase L chain, ATP binding K01955 - 6.3.5.5 0.0 1551.0
TH2_k127_4189886_1 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1054.0
TH2_k127_4189886_10 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000001544 109.0
TH2_k127_4189886_11 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000001664 107.0
TH2_k127_4189886_12 cellulase activity - - - 0.0000000000000000000003834 103.0
TH2_k127_4189886_13 Domain of unknown function (DUF4295) - - - 0.0000000000000002657 79.0
TH2_k127_4189886_14 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0002687 53.0
TH2_k127_4189886_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 4.151e-212 665.0
TH2_k127_4189886_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 588.0
TH2_k127_4189886_4 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 546.0
TH2_k127_4189886_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 533.0
TH2_k127_4189886_6 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 512.0
TH2_k127_4189886_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009031 456.0
TH2_k127_4189886_8 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 331.0
TH2_k127_4189886_9 - - - - 0.000000000000000000000000000000000000004874 148.0
TH2_k127_423682_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0 2149.0
TH2_k127_423682_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1041.0
TH2_k127_423682_10 Methylase involved in ubiquinone menaquinone biosynthesis K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 406.0
TH2_k127_423682_11 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 403.0
TH2_k127_423682_12 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 383.0
TH2_k127_423682_13 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 353.0
TH2_k127_423682_14 Molybdenum cofactor biosynthesis protein K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 356.0
TH2_k127_423682_15 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 337.0
TH2_k127_423682_16 epimerase dehydratase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 326.0
TH2_k127_423682_17 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 317.0
TH2_k127_423682_18 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 296.0
TH2_k127_423682_19 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001585 278.0
TH2_k127_423682_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1005.0
TH2_k127_423682_20 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006746 276.0
TH2_k127_423682_21 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001889 278.0
TH2_k127_423682_22 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004264 254.0
TH2_k127_423682_23 COG1228 Imidazolonepropionase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000002413 244.0
TH2_k127_423682_24 SPTR Conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003497 256.0
TH2_k127_423682_25 Domain of unknown function (DUF1858) - - - 0.00000000000000000000000000000000000000000000000000000000000000004998 231.0
TH2_k127_423682_26 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000001799 222.0
TH2_k127_423682_27 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000000000000000000000000000000000000000000000003839 218.0
TH2_k127_423682_28 - catabolite gene activator and regulatory subunit of cAMP-dependent protein K01420 - - 0.00000000000000000000000000000000000000000000000000001746 197.0
TH2_k127_423682_29 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000001848 183.0
TH2_k127_423682_3 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 5.831e-293 902.0
TH2_k127_423682_30 Thioredoxin - - - 0.00000000000000000000000000000000000000000000002081 177.0
TH2_k127_423682_31 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000004469 164.0
TH2_k127_423682_32 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000009154 162.0
TH2_k127_423682_33 Domain of unknown function (DUF4920) - - - 0.00000000000000000000000000000000000000004116 156.0
TH2_k127_423682_34 TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000004133 162.0
TH2_k127_423682_35 Molybdopterin converting factor K03635 - 2.8.1.12 0.00000000000000000000000000000000000000006897 155.0
TH2_k127_423682_36 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000002534 151.0
TH2_k127_423682_38 Translation initiation factor K03113 - - 0.0000000000000000000000000000000000001092 144.0
TH2_k127_423682_39 porT protein - - - 0.000000000000000000000000000000003855 138.0
TH2_k127_423682_4 Transporter K02575 - - 1.842e-247 773.0
TH2_k127_423682_40 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000005107 116.0
TH2_k127_423682_41 Putative beta-lactamase-inhibitor-like, PepSY-like - - - 0.0000000000000000000000001835 111.0
TH2_k127_423682_42 Transcription elongation factor - - - 0.0000000000000000000000002527 111.0
TH2_k127_423682_43 PFAM Cytochrome c, class I - - - 0.0000000000000000000000004361 113.0
TH2_k127_423682_44 Pfam:DUF59 - - - 0.000000000000000000000002282 105.0
TH2_k127_423682_45 Protein of unknown function (DUF2490) - - - 0.00000000000000000000001485 111.0
TH2_k127_423682_46 - - - - 0.0000000000000000000002319 97.0
TH2_k127_423682_47 - - - - 0.000000000000000000002411 100.0
TH2_k127_423682_48 2TM domain - - - 0.000000000000000000007484 94.0
TH2_k127_423682_49 - - - - 0.000000000000000006223 89.0
TH2_k127_423682_5 Asparaginyl-tRNA synthetase K01893 - 6.1.1.22 1.389e-244 762.0
TH2_k127_423682_50 Tetratricopeptide repeat - - - 0.0000000000000001921 88.0
TH2_k127_423682_51 CRP FNR family transcriptional regulator K01420 - - 0.00000000000005704 80.0
TH2_k127_423682_52 - - - - 0.000000000002951 72.0
TH2_k127_423682_53 Tetratricopeptide repeat - - - 0.000000000007204 77.0
TH2_k127_423682_54 FAD dependent oxidoreductase K07137 - - 0.00000000001306 68.0
TH2_k127_423682_55 - - - - 0.000000001271 66.0
TH2_k127_423682_56 Mo-molybdopterin cofactor metabolic process K03636 - - 0.0000006168 54.0
TH2_k127_423682_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.343e-227 719.0
TH2_k127_423682_7 2-Nitropropane dioxygenase - - - 2.918e-217 689.0
TH2_k127_423682_8 PFAM Major facilitator superfamily K02575 - - 1.89e-196 628.0
TH2_k127_423682_9 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 492.0
TH2_k127_424003_0 TonB-dependent receptor K02014 - - 2.524e-256 814.0
TH2_k127_424003_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.367e-209 656.0
TH2_k127_424003_10 GSCFA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001088 273.0
TH2_k127_424003_11 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001497 269.0
TH2_k127_424003_12 metallopeptidase activity K01337 - 3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000000000002709 280.0
TH2_k127_424003_13 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000017 229.0
TH2_k127_424003_14 Peptide-methionine (R)-S-oxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000001855 215.0
TH2_k127_424003_15 - - - - 0.0000000000000000000000000000000000000000000000002924 187.0
TH2_k127_424003_16 Protease prsW family - - - 0.00000000000000000000000000000000000000000000001589 187.0
TH2_k127_424003_17 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000002392 168.0
TH2_k127_424003_18 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000248 158.0
TH2_k127_424003_19 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000002667 153.0
TH2_k127_424003_2 tRNA nucleotidyltransferase K00970,K00974 - 2.7.7.19,2.7.7.72 1.434e-204 646.0
TH2_k127_424003_20 Type IX secretion system membrane protein PorP/SprF - - - 0.0000000000000000000000000000000004307 143.0
TH2_k127_424003_21 PFAM Membrane protein of K08972 - - 0.00000000000000000000000000000009188 129.0
TH2_k127_424003_22 C-terminal domain of CHU protein family - - - 0.0000000000000000000000000000001727 136.0
TH2_k127_424003_23 domain protein K12287,K12549,K13735,K20276 - - 0.000000000000000000000000000001837 141.0
TH2_k127_424003_24 YceI-like domain - - - 0.000000000000000002872 100.0
TH2_k127_424003_25 Gliding motility-associated C-terminal domain - - - 0.00000000000000006936 93.0
TH2_k127_424003_26 - - - - 0.0000000000000811 78.0
TH2_k127_424003_27 - K07184,K07777,K12065,K13527 - 2.7.13.3 0.0000000003762 70.0
TH2_k127_424003_3 COG3893 Inactivated superfamily I helicase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 570.0
TH2_k127_424003_4 Belongs to the DEAD box helicase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 536.0
TH2_k127_424003_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 491.0
TH2_k127_424003_6 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 443.0
TH2_k127_424003_7 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 385.0
TH2_k127_424003_8 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 304.0
TH2_k127_424003_9 C-terminal domain of CHU protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 318.0
TH2_k127_4401881_0 TonB dependent receptor K16087 - - 9.59e-216 695.0
TH2_k127_4401881_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 556.0
TH2_k127_4401881_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 420.0
TH2_k127_4401881_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000001613 247.0
TH2_k127_4401881_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000003577 237.0
TH2_k127_4401881_5 integral membrane protein K07027 - - 0.000000000000000000000000000000000000000000000000000000000008802 219.0
TH2_k127_4401881_6 Cytidylyltransferase-like K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000003397 186.0
TH2_k127_4401881_7 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000003256 177.0
TH2_k127_4494902_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1285.0
TH2_k127_4494902_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.566e-215 674.0
TH2_k127_4494902_2 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 319.0
TH2_k127_4494902_3 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001173 278.0
TH2_k127_4494902_4 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000002955 132.0
TH2_k127_4494902_5 Chain length determinant protein - - - 0.00000000000000000000008067 104.0
TH2_k127_4494902_6 Conserved repeat domain - - - 0.000000000000000000008812 105.0
TH2_k127_4494902_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000001919 64.0
TH2_k127_4519501_0 Transport of potassium into the cell K03549 - - 3.167e-283 883.0
TH2_k127_4519501_1 Mg chelatase-like protein K07391 - - 1.15e-233 733.0
TH2_k127_4519501_10 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 424.0
TH2_k127_4519501_11 Belongs to the aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 403.0
TH2_k127_4519501_12 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 380.0
TH2_k127_4519501_13 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 376.0
TH2_k127_4519501_14 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 377.0
TH2_k127_4519501_15 Alanine dehydrogenase/PNT, C-terminal domain K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 368.0
TH2_k127_4519501_16 benzoyl-CoA reductase K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 368.0
TH2_k127_4519501_17 PFAM Bacterial trigger factor protein (TF) K03545 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 366.0
TH2_k127_4519501_18 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005432 281.0
TH2_k127_4519501_19 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000005904 265.0
TH2_k127_4519501_2 Oligoendopeptidase F K08602 - - 1.014e-214 680.0
TH2_k127_4519501_20 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000002875 256.0
TH2_k127_4519501_21 polyketide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001702 269.0
TH2_k127_4519501_22 Esterase PHB depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007773 260.0
TH2_k127_4519501_23 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059,K00216 - 1.1.1.100,1.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000001303 249.0
TH2_k127_4519501_24 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005878 264.0
TH2_k127_4519501_25 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000002738 235.0
TH2_k127_4519501_26 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000001944 209.0
TH2_k127_4519501_27 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000009241 183.0
TH2_k127_4519501_28 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000004419 195.0
TH2_k127_4519501_29 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000122 189.0
TH2_k127_4519501_3 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 608.0
TH2_k127_4519501_30 maturation factor XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000003406 177.0
TH2_k127_4519501_31 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000002806 173.0
TH2_k127_4519501_32 MobA-like NTP transferase domain - - - 0.0000000000002095 78.0
TH2_k127_4519501_33 - - - - 0.000000000003055 72.0
TH2_k127_4519501_34 hemerythrin HHE cation binding domain - - - 0.0000000297 62.0
TH2_k127_4519501_4 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 626.0
TH2_k127_4519501_5 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 561.0
TH2_k127_4519501_6 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 571.0
TH2_k127_4519501_7 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 512.0
TH2_k127_4519501_8 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 470.0
TH2_k127_4519501_9 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 431.0
TH2_k127_45222_0 SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000000000000519 187.0
TH2_k127_45222_1 Uncharacterized conserved protein (DUF2075) K09384 - - 0.00000000000000000000000000000000000000000611 156.0
TH2_k127_45222_2 PAP2 superfamily C-terminal - - - 0.000000000000000000000000000000000229 138.0
TH2_k127_45222_4 PAP2 superfamily C-terminal - - - 0.0002543 44.0
TH2_k127_4525910_0 formate dehydrogenase (NAD+) activity K00123,K05299 - 1.17.1.10,1.17.1.9 0.0 1439.0
TH2_k127_4525910_1 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 9.597e-277 859.0
TH2_k127_4525910_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.147e-276 859.0
TH2_k127_4525910_3 aminoacyl-histidine dipeptidase K01270 - - 1.017e-240 751.0
TH2_k127_4525910_4 FdhD/NarQ family K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 304.0
TH2_k127_4525910_5 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000001133 260.0
TH2_k127_4525910_6 - K07004 - - 0.000000000000000000000000000000000000000000000000000000000008079 221.0
TH2_k127_4525910_7 - - - - 0.000000000000000000003019 96.0
TH2_k127_4525910_8 Domain of unknown function (DUF1987) - - - 0.000000000000000006558 88.0
TH2_k127_4527453_0 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 452.0
TH2_k127_4527453_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 357.0
TH2_k127_4527453_2 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 336.0
TH2_k127_4527453_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001674 263.0
TH2_k127_4527453_4 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000007019 213.0
TH2_k127_4527453_5 TIGRFAM Bacteroidetes-specific - - - 0.000000000000000000000000000000000000000000000000004265 192.0
TH2_k127_4527453_6 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000001026 181.0
TH2_k127_4527453_7 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000002798 175.0
TH2_k127_4527453_8 Domain of unknown function (DUF1987) - - - 0.00000000001201 69.0
TH2_k127_4527453_9 Belongs to the ompA family K12216 - - 0.00005801 57.0
TH2_k127_4569193_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1315.0
TH2_k127_4569193_1 cobalamin-transporting ATPase activity - - - 1.138e-235 760.0
TH2_k127_4569193_10 Cytosol aminopeptidase family, catalytic domain K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 474.0
TH2_k127_4569193_11 Homoserine dehydrogenase, NAD binding domain K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 464.0
TH2_k127_4569193_12 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 450.0
TH2_k127_4569193_13 Belongs to the PdxA family K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 441.0
TH2_k127_4569193_14 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 423.0
TH2_k127_4569193_15 Sigma factor PP2C-like phosphatases K02660,K07315,K17763,K20971,K21009 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 462.0
TH2_k127_4569193_16 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 385.0
TH2_k127_4569193_17 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 380.0
TH2_k127_4569193_18 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 382.0
TH2_k127_4569193_19 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 368.0
TH2_k127_4569193_2 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 1.425e-226 704.0
TH2_k127_4569193_20 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 324.0
TH2_k127_4569193_21 Phosphoribosyl-AMP cyclohydrolase K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 291.0
TH2_k127_4569193_22 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 267.0
TH2_k127_4569193_23 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000123 254.0
TH2_k127_4569193_24 PFAM MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000006258 210.0
TH2_k127_4569193_25 Membrane - - - 0.000000000000000000000000000000000000000000000000000001223 207.0
TH2_k127_4569193_26 membrane K08994 - - 0.00000000000000000000000000000000000000000000007296 174.0
TH2_k127_4569193_27 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000001209 159.0
TH2_k127_4569193_28 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000007659 145.0
TH2_k127_4569193_29 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000131 127.0
TH2_k127_4569193_3 PFAM PKD domain - - - 2.915e-226 751.0
TH2_k127_4569193_30 HemY protein - - - 0.000000001432 63.0
TH2_k127_4569193_31 MORN repeat variant - - - 0.000000003113 69.0
TH2_k127_4569193_4 Radical SAM K11784 - 1.21.98.1 5.363e-196 616.0
TH2_k127_4569193_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 569.0
TH2_k127_4569193_6 belongs to the imidazoleglycerol-phosphate dehydratase family K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 545.0
TH2_k127_4569193_7 Outer membrane protein beta-barrel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 516.0
TH2_k127_4569193_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 487.0
TH2_k127_4569193_9 tRNA synthetases class II core domain (F) K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 485.0
TH2_k127_4633606_0 PFAM Peptidase M16 inactive domain K07263 - - 8.508e-318 999.0
TH2_k127_4633606_1 NeuB family K01654,K15898 - 2.5.1.56,2.5.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 514.0
TH2_k127_4633606_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000007458 210.0
TH2_k127_4633606_11 pseudaminic acid biosynthesis-associated protein PseG - - - 0.000000000000000000000000000000000000000000000000000000001889 218.0
TH2_k127_4633606_12 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002516 175.0
TH2_k127_4633606_13 metallopeptidase activity K01337 - 3.4.21.50 0.000000000000000000000000000000000000000000002635 179.0
TH2_k127_4633606_15 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000006261 70.0
TH2_k127_4633606_2 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 459.0
TH2_k127_4633606_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 368.0
TH2_k127_4633606_4 SPTR Conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 396.0
TH2_k127_4633606_5 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 350.0
TH2_k127_4633606_6 Mandelate racemase muconate lactonizing enzyme K01776,K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20,5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 348.0
TH2_k127_4633606_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 341.0
TH2_k127_4633606_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000365 287.0
TH2_k127_4633606_9 Cytidylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001951 271.0
TH2_k127_4658081_0 Histidine ammonia-lyase K01745 - 4.3.1.3 2.39e-214 676.0
TH2_k127_4658081_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 314.0
TH2_k127_4658081_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 303.0
TH2_k127_4658081_3 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000001493 232.0
TH2_k127_4658081_4 - - - - 0.0000000000000000000000000000000000000000000000005258 184.0
TH2_k127_4658081_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000001466 112.0
TH2_k127_4658081_6 - - - - 0.00002329 54.0
TH2_k127_4720931_0 PFAM Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 406.0
TH2_k127_4720931_1 PFAM Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 390.0
TH2_k127_4720931_2 PFAM peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 391.0
TH2_k127_4720931_3 peptidase activity, acting on L-amino acid peptides K01337,K13735,K20276 - 3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000001175 264.0
TH2_k127_4720931_4 PKD domain - - - 0.000000000000000000000000000000000000000000000000002566 209.0
TH2_k127_4720931_5 Pfam Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000002677 144.0
TH2_k127_4720931_6 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000003089 124.0
TH2_k127_4720931_7 Conserved repeat domain - - - 0.0000000000000000000000001624 124.0
TH2_k127_4809071_0 with chaperone activity ATP-binding subunit K03696 - - 0.0 1094.0
TH2_k127_4809071_1 C-terminal domain of CHU protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 463.0
TH2_k127_4809071_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 313.0
TH2_k127_4809071_3 ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000004438 137.0
TH2_k127_4809071_4 PFAM ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000000000000000005572 109.0
TH2_k127_4828729_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.422e-266 838.0
TH2_k127_4828729_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.14e-212 669.0
TH2_k127_4828729_10 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 375.0
TH2_k127_4828729_11 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 357.0
TH2_k127_4828729_12 KR domain K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 347.0
TH2_k127_4828729_13 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002156 274.0
TH2_k127_4828729_14 Polypeptide deformylase K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000002016 263.0
TH2_k127_4828729_15 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000003016 187.0
TH2_k127_4828729_16 MaoC domain protein dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000001398 171.0
TH2_k127_4828729_17 PFAM Biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000002931 177.0
TH2_k127_4828729_18 DinB superfamily - - - 0.000000000000000000000000000000000000000001921 161.0
TH2_k127_4828729_19 Ribosomal silencing factor during starvation K09710 - - 0.00000000000000000000000000000000000003761 150.0
TH2_k127_4828729_2 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 2.844e-209 664.0
TH2_k127_4828729_20 Domain of unknown function (DUF3127) - - - 0.0000000000000000000000000000000007235 134.0
TH2_k127_4828729_21 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.00000000000000000000000000000002059 142.0
TH2_k127_4828729_22 YbbR-like protein - - - 0.00000000000000000000000000000004559 137.0
TH2_k127_4828729_23 Protein of unknown function (DUF1573) - - - 0.000000000000000000000000000002803 126.0
TH2_k127_4828729_24 Preprotein translocase subunit YajC K03210 - - 0.00000000000000000000000005109 110.0
TH2_k127_4828729_25 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000003839 115.0
TH2_k127_4828729_26 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000008376 97.0
TH2_k127_4828729_27 amino acid peptide transporter K03305 - - 0.00000000001923 64.0
TH2_k127_4828729_28 - - - - 0.000000001409 69.0
TH2_k127_4828729_29 Pregnancy-associated plasma protein-A - - - 0.000000007322 68.0
TH2_k127_4828729_3 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 538.0
TH2_k127_4828729_30 Peptide-N-glycosidase F, C terminal - - - 0.0000003676 63.0
TH2_k127_4828729_31 - - - - 0.0000003744 57.0
TH2_k127_4828729_32 protein trimerization K05807 - - 0.000000651 59.0
TH2_k127_4828729_33 - - - - 0.0005617 48.0
TH2_k127_4828729_4 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 517.0
TH2_k127_4828729_5 PFAM Alanine dehydrogenase PNT, C-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 499.0
TH2_k127_4828729_6 PHB de-polymerase C-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 475.0
TH2_k127_4828729_7 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 439.0
TH2_k127_4828729_8 TIGRFAM flavoprotein, HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 436.0
TH2_k127_4828729_9 1-alkyl-2-acetylglycerophosphocholine esterase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 422.0
TH2_k127_4855079_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.216e-306 949.0
TH2_k127_4855079_1 Peptidase S46 - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 2.531e-298 930.0
TH2_k127_4855079_10 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000001557 222.0
TH2_k127_4855079_11 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000001033 214.0
TH2_k127_4855079_12 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000005946 183.0
TH2_k127_4855079_13 - - - - 0.0000000000000000000000000000000000000000000000002697 184.0
TH2_k127_4855079_14 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000005414 165.0
TH2_k127_4855079_15 ORF6N domain - - - 0.00000000000000000000000000000009138 127.0
TH2_k127_4855079_16 FeoA K04758 - - 0.0000000000000000000002882 99.0
TH2_k127_4855079_17 repeat protein - - - 0.000000000000002537 82.0
TH2_k127_4855079_18 COG3209 Rhs family protein - - - 0.0002017 55.0
TH2_k127_4855079_2 OmpA family - - - 8.802e-211 675.0
TH2_k127_4855079_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 5.311e-205 658.0
TH2_k127_4855079_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 466.0
TH2_k127_4855079_5 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 439.0
TH2_k127_4855079_6 PFAM PKD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000854 426.0
TH2_k127_4855079_7 amidohydrolase K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 309.0
TH2_k127_4855079_8 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 310.0
TH2_k127_4855079_9 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000000000000002821 229.0
TH2_k127_4877282_0 Polysaccharide biosynthesis protein - - - 3e-206 659.0
TH2_k127_4877282_1 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 546.0
TH2_k127_4877282_2 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 538.0
TH2_k127_4887314_0 Protein of unknown function (DUF2723) - - - 2.769e-298 949.0
TH2_k127_4887314_1 TonB-dependent receptor plug - - - 6.852e-292 916.0
TH2_k127_4887314_10 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 429.0
TH2_k127_4887314_11 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 397.0
TH2_k127_4887314_12 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 398.0
TH2_k127_4887314_13 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 378.0
TH2_k127_4887314_14 2 iron, 2 sulfur cluster binding K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 377.0
TH2_k127_4887314_15 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 334.0
TH2_k127_4887314_16 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 307.0
TH2_k127_4887314_17 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 307.0
TH2_k127_4887314_18 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 304.0
TH2_k127_4887314_19 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 319.0
TH2_k127_4887314_2 Aldehyde dehydrogenase family K00294,K13821 - 1.2.1.88,1.5.5.2 1.057e-281 872.0
TH2_k127_4887314_20 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 290.0
TH2_k127_4887314_21 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 289.0
TH2_k127_4887314_22 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 290.0
TH2_k127_4887314_23 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 297.0
TH2_k127_4887314_24 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001815 284.0
TH2_k127_4887314_25 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009015 283.0
TH2_k127_4887314_26 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007586 279.0
TH2_k127_4887314_27 Stage II sporulation protein E (SpoIIE) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004591 294.0
TH2_k127_4887314_28 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007074 287.0
TH2_k127_4887314_29 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002018 244.0
TH2_k127_4887314_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.388e-266 827.0
TH2_k127_4887314_30 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004425 247.0
TH2_k127_4887314_31 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001408 240.0
TH2_k127_4887314_32 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000001042 232.0
TH2_k127_4887314_33 TIGRFAM TIGR02453 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000008359 217.0
TH2_k127_4887314_34 Domain of unknown function (DUF4290) - - - 0.000000000000000000000000000000000000000000000000000000000006949 214.0
TH2_k127_4887314_35 - - - - 0.0000000000000000000000000000000000000000000000000000000001093 220.0
TH2_k127_4887314_36 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000002096 199.0
TH2_k127_4887314_37 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000003447 204.0
TH2_k127_4887314_38 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000924 196.0
TH2_k127_4887314_39 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000005833 169.0
TH2_k127_4887314_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.233e-219 686.0
TH2_k127_4887314_40 - - - - 0.0000000000000000000000000000000000000005272 153.0
TH2_k127_4887314_41 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000001112 153.0
TH2_k127_4887314_42 Domain of unknown function (DUF4249) - - - 0.000000000000000000000000000000000000001874 158.0
TH2_k127_4887314_43 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000004101 146.0
TH2_k127_4887314_44 - - - - 0.000000000000000000000000000005656 126.0
TH2_k127_4887314_45 Belongs to the ompA family - - - 0.0000000000000000000000000002777 129.0
TH2_k127_4887314_46 Large extracellular alpha-helical protein - - - 0.000000000000000000000000000788 126.0
TH2_k127_4887314_47 - - - - 0.0000000000000000000000003051 118.0
TH2_k127_4887314_48 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000003745 98.0
TH2_k127_4887314_49 Protein of unknown function (DUF3347) - - - 0.000000000000000000008485 97.0
TH2_k127_4887314_5 PFAM Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 554.0
TH2_k127_4887314_50 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000008789 98.0
TH2_k127_4887314_51 Endonuclease containing a URI domain K01154,K07461 - 3.1.21.3 0.0000000000000000001125 91.0
TH2_k127_4887314_52 - - - - 0.00000000000000005354 92.0
TH2_k127_4887314_53 Belongs to the ompA family - - - 0.0000000000000001021 93.0
TH2_k127_4887314_54 Protein of unknown function (DUF2752) - - - 0.0000000000000001436 82.0
TH2_k127_4887314_55 cAMP biosynthetic process - - - 0.00000000000001038 84.0
TH2_k127_4887314_56 regulation of response to stimulus - - - 0.0000000002012 72.0
TH2_k127_4887314_58 - K07126 - - 0.000002121 58.0
TH2_k127_4887314_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 522.0
TH2_k127_4887314_62 MORN repeat variant - - - 0.00004683 51.0
TH2_k127_4887314_64 Belongs to the ompA family - - - 0.0008495 51.0
TH2_k127_4887314_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 500.0
TH2_k127_4887314_8 Thioredoxin reductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 486.0
TH2_k127_4887314_9 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254 - 1.3.5.2,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 477.0
TH2_k127_4896444_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 2.356e-257 800.0
TH2_k127_4896444_1 Heat shock 70 kDa protein K04043 - - 1.678e-255 792.0
TH2_k127_4896444_10 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000002385 167.0
TH2_k127_4896444_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000005804 128.0
TH2_k127_4896444_12 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000001708 91.0
TH2_k127_4896444_13 - - - - 0.000000000005155 77.0
TH2_k127_4896444_14 Domain of unknown function (DUF4270) - - - 0.00000003486 66.0
TH2_k127_4896444_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 430.0
TH2_k127_4896444_3 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 383.0
TH2_k127_4896444_4 Starch synthase catalytic domain K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 350.0
TH2_k127_4896444_5 ATPase of the PP-loop superfamily implicated in cell cycle control - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 351.0
TH2_k127_4896444_6 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 346.0
TH2_k127_4896444_7 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 290.0
TH2_k127_4896444_8 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003872 293.0
TH2_k127_4896444_9 ORF6N domain - - - 0.00000000000000000000000000000000000000000000000000364 187.0
TH2_k127_4917427_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1067.0
TH2_k127_4917427_1 Cystathionine beta-synthase K01697 - 4.2.1.22 2.601e-208 656.0
TH2_k127_4917427_10 of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 357.0
TH2_k127_4917427_11 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 325.0
TH2_k127_4917427_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001623 299.0
TH2_k127_4917427_13 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005898 274.0
TH2_k127_4917427_14 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007719 251.0
TH2_k127_4917427_15 Phosphoesterase K07095 - - 0.00000000000000000000000000000000000000000000000000000000000000000002503 235.0
TH2_k127_4917427_16 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826,K02619 - 2.6.1.42,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000005926 239.0
TH2_k127_4917427_17 Rhomboid family - - - 0.00000000000000000000000000000000000000001708 160.0
TH2_k127_4917427_18 Protein of unknown function (DUF3467) - - - 0.0000000000000000000000000000000000000007431 149.0
TH2_k127_4917427_19 Acyltransferase family - - - 0.000000000000000000000000001109 124.0
TH2_k127_4917427_2 acyl-CoA dehydrogenase - - - 1.065e-207 649.0
TH2_k127_4917427_20 Belongs to the ompA family - - - 0.00000000000000000000000000497 125.0
TH2_k127_4917427_21 Methyltransferase domain - - - 0.0000000000000000000000004613 116.0
TH2_k127_4917427_22 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000004607 91.0
TH2_k127_4917427_23 Tetratricopeptide repeats - - - 0.000000000009548 78.0
TH2_k127_4917427_24 - - - - 0.0000003439 62.0
TH2_k127_4917427_25 endonuclease I - - - 0.000002425 55.0
TH2_k127_4917427_3 Mur ligase middle domain K01924,K02558 - 6.3.2.45,6.3.2.8 5.43e-200 631.0
TH2_k127_4917427_4 PFAM Aminotransferase class I and II K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 591.0
TH2_k127_4917427_5 agmatine deiminase activity K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 509.0
TH2_k127_4917427_6 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 433.0
TH2_k127_4917427_7 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 400.0
TH2_k127_4917427_8 Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 415.0
TH2_k127_4917427_9 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 364.0
TH2_k127_4930680_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit K11381 - 1.2.4.4 2.77e-307 954.0
TH2_k127_4930680_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.891e-271 849.0
TH2_k127_4930680_10 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 306.0
TH2_k127_4930680_11 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001757 280.0
TH2_k127_4930680_12 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000001216 274.0
TH2_k127_4930680_13 negative regulation of protein lipidation K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001287 289.0
TH2_k127_4930680_14 TIGRFAM lycopene cyclase domain - - - 0.000000000000000000000000000000000000000000000000000000000000001339 225.0
TH2_k127_4930680_15 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000004547 226.0
TH2_k127_4930680_16 MafB19-like deaminase K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000005683 218.0
TH2_k127_4930680_17 Isopentenyl-diphosphate delta-isomerase K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000003129 199.0
TH2_k127_4930680_18 - - - - 0.000000000000000000000000000000000000000000000000000002413 211.0
TH2_k127_4930680_19 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000004779 187.0
TH2_k127_4930680_2 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 3.376e-194 616.0
TH2_k127_4930680_20 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000141 181.0
TH2_k127_4930680_21 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000000000000000000000000000000005688 183.0
TH2_k127_4930680_22 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000112 137.0
TH2_k127_4930680_23 PFAM Sulfotransferase domain - - - 0.000000000000000000000000000000006799 139.0
TH2_k127_4930680_24 PFAM sulfotransferase - - - 0.000000000000000000000000000000009105 138.0
TH2_k127_4930680_25 peptidyl-prolyl isomerase K03771 - 5.2.1.8 0.00000000000000000000000000003697 120.0
TH2_k127_4930680_26 Sulfotransferase family - - - 0.0000000000000000000000000005199 123.0
TH2_k127_4930680_27 - - - - 0.000000000000000000000004375 112.0
TH2_k127_4930680_28 Redoxin family - - - 0.00000000000000000000002062 108.0
TH2_k127_4930680_29 Protein of unknown function (DUF3347) - - - 0.0000000000000000001686 93.0
TH2_k127_4930680_3 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 608.0
TH2_k127_4930680_30 Phosphopantetheine attachment site - - - 0.0000000000006027 71.0
TH2_k127_4930680_32 C-terminal domain of CHU protein family - - - 0.00000009662 64.0
TH2_k127_4930680_34 Parallel beta-helix repeats - - - 0.0003281 53.0
TH2_k127_4930680_4 Phytoene dehydrogenase and related K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 558.0
TH2_k127_4930680_5 acetoacetate metabolism regulatory protein AtoC K07714 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 534.0
TH2_k127_4930680_6 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 503.0
TH2_k127_4930680_7 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 502.0
TH2_k127_4930680_8 Squalene/phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 362.0
TH2_k127_4930680_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 356.0
TH2_k127_493073_0 Belongs to the heme-copper respiratory oxidase family K15862 - 1.9.3.1 0.0 1119.0
TH2_k127_493073_1 cytochrome c oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 600.0
TH2_k127_493073_2 PFAM Cytochrome c, class I K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003715 282.0
TH2_k127_493073_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000134 224.0
TH2_k127_493073_4 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.00000000000000336 77.0
TH2_k127_493073_5 Cytochrome c - - - 0.00000000000009496 72.0
TH2_k127_493073_6 FixH K09926 - - 0.0004082 44.0
TH2_k127_4931961_0 PFAM Carbamoyl-phosphate synthase L chain, ATP binding K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 4.647e-226 709.0
TH2_k127_4931961_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 404.0
TH2_k127_4931961_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 398.0
TH2_k127_4931961_3 OstA-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 382.0
TH2_k127_4931961_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 351.0
TH2_k127_4931961_5 Permease, YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 349.0
TH2_k127_4931961_6 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 318.0
TH2_k127_4931961_7 - - - - 0.00000000000000000000000000000000000000000005191 172.0
TH2_k127_4931961_8 Domain of unknown function (DUF4294) - - - 0.0000000000000000000000000000000000000003639 156.0
TH2_k127_4931961_9 Plasmid pRiA4b ORF-3-like protein - - - 0.000000000000000000000000000007281 128.0
TH2_k127_4946911_0 amino acid K03294 - - 1.13e-246 768.0
TH2_k127_4946911_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 9.009e-233 728.0
TH2_k127_4946911_10 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 336.0
TH2_k127_4946911_11 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 327.0
TH2_k127_4946911_12 Efflux ABC transporter, permease protein K09808,K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 308.0
TH2_k127_4946911_13 AAA domain, putative AbiEii toxin, Type IV TA system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000002236 212.0
TH2_k127_4946911_14 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000002488 189.0
TH2_k127_4946911_15 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000001465 194.0
TH2_k127_4946911_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000335 150.0
TH2_k127_4946911_17 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000007618 122.0
TH2_k127_4946911_18 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000005728 121.0
TH2_k127_4946911_19 C-terminal domain of CHU protein family - - - 0.0000000000000000000004872 106.0
TH2_k127_4946911_2 COGs COG1033 exporter of the RND superfamily protein K07003 - - 2.209e-222 715.0
TH2_k127_4946911_20 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.000006783 49.0
TH2_k127_4946911_22 - - - - 0.00003142 55.0
TH2_k127_4946911_3 ABC transporter transmembrane region K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 559.0
TH2_k127_4946911_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 482.0
TH2_k127_4946911_5 THUMP K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 401.0
TH2_k127_4946911_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 365.0
TH2_k127_4946911_7 Acyl-CoA reductase (LuxC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 354.0
TH2_k127_4946911_8 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 353.0
TH2_k127_4946911_9 efflux protein, MATE family K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 344.0
TH2_k127_4948516_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 306.0
TH2_k127_4948516_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000006305 181.0
TH2_k127_4948516_2 RNA pseudouridylate synthase K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000002417 182.0
TH2_k127_4948516_3 Pectate lyase - - - 0.000000000000000000000000294 123.0
TH2_k127_4948516_4 Endonuclease I - - - 0.00004365 57.0
TH2_k127_4952725_0 TonB-dependent receptor - - - 2.044e-251 806.0
TH2_k127_4952725_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 556.0
TH2_k127_4952725_2 Phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009615 501.0
TH2_k127_4952725_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.0000000000000000000000000000000000000000000000000000000001274 207.0
TH2_k127_4952725_4 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000373 128.0
TH2_k127_4952725_5 phosphate transporter K03306 - - 0.0000000000004708 69.0
TH2_k127_4957603_0 - - - - 0.000000000000000000000000000000000000009173 164.0
TH2_k127_4957603_1 - - - - 0.00000000000000000000000000000001743 141.0
TH2_k127_4957603_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000001125 126.0
TH2_k127_4957603_3 cellulase activity K01179 - 3.2.1.4 0.0000000000000000000009449 98.0
TH2_k127_5006380_0 amidohydrolase - - - 3.006e-314 992.0
TH2_k127_5006380_1 PFAM Penicillin binding protein transpeptidase domain K05366 - 2.4.1.129,3.4.16.4 3.92e-252 797.0
TH2_k127_5006380_10 COG1247 Sortase and related acyltransferases K03823 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000000001427 221.0
TH2_k127_5006380_11 probably involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000002646 172.0
TH2_k127_5006380_12 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000825 158.0
TH2_k127_5006380_13 HAD family hydrolase - - - 0.00000000000000000000000000000006431 132.0
TH2_k127_5006380_14 - - - - 0.0000000000000000000000000003312 130.0
TH2_k127_5006380_15 methyltransferase activity K02169,K15984 - 2.1.1.197,2.1.1.242 0.000000000000000000001276 102.0
TH2_k127_5006380_16 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000001951 106.0
TH2_k127_5006380_17 Pkd domain containing protein - - - 0.00000000000171 81.0
TH2_k127_5006380_19 SdrD B-like domain - - - 0.00002198 57.0
TH2_k127_5006380_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 563.0
TH2_k127_5006380_20 metallopeptidase activity - - - 0.0008048 52.0
TH2_k127_5006380_3 amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 524.0
TH2_k127_5006380_4 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 421.0
TH2_k127_5006380_5 PFAM Coenzyme A transferase K01027,K01028,K01031,K01034 - 2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 408.0
TH2_k127_5006380_6 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 407.0
TH2_k127_5006380_7 PFAM Coenzyme A transferase K01029,K01032 - 2.8.3.5,2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 393.0
TH2_k127_5006380_8 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 295.0
TH2_k127_5006380_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002633 262.0
TH2_k127_5011141_0 Endoribonuclease that initiates mRNA decay K18682 - - 3.22e-228 717.0
TH2_k127_5011141_1 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 515.0
TH2_k127_5011141_10 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000004836 162.0
TH2_k127_5011141_11 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000000000003512 100.0
TH2_k127_5011141_12 Polysaccharide biosynthesis protein - - - 0.00000000000001373 87.0
TH2_k127_5011141_13 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000004456 70.0
TH2_k127_5011141_14 Pkd domain containing protein - - - 0.0000005073 61.0
TH2_k127_5011141_15 Belongs to the ompA family - - - 0.000001196 60.0
TH2_k127_5011141_2 Belongs to the BshC family K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 402.0
TH2_k127_5011141_3 phosphorylase K00757 - 2.4.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 319.0
TH2_k127_5011141_4 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 324.0
TH2_k127_5011141_5 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 310.0
TH2_k127_5011141_6 uracil phosphoribosyltransferase K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 289.0
TH2_k127_5011141_7 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 303.0
TH2_k127_5011141_8 Bacterial sugar transferase K21303 - 2.7.8.40 0.00000000000000000000000000000000000000000000000000000000000000000002856 237.0
TH2_k127_5011141_9 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000002345 213.0
TH2_k127_5107975_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1437.0
TH2_k127_5107975_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.792e-288 890.0
TH2_k127_5107975_10 Transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 367.0
TH2_k127_5107975_11 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 344.0
TH2_k127_5107975_12 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 335.0
TH2_k127_5107975_13 component I K01665,K03342 - 2.6.1.85,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 328.0
TH2_k127_5107975_14 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 316.0
TH2_k127_5107975_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 287.0
TH2_k127_5107975_16 Male sterility protein K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000002411 267.0
TH2_k127_5107975_17 Translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000006615 250.0
TH2_k127_5107975_18 Psort location Cytoplasmic, score 8.96 K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007826 252.0
TH2_k127_5107975_19 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000000001089 251.0
TH2_k127_5107975_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 571.0
TH2_k127_5107975_20 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005401 262.0
TH2_k127_5107975_21 Dialkylrecorsinol condensing enzyme DarA - - - 0.000000000000000000000000000000000000000000000000000000000000000003458 236.0
TH2_k127_5107975_22 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000007533 177.0
TH2_k127_5107975_23 Molecular chaperone DnaK - - - 0.0000000000000000000000000000000000000000004098 171.0
TH2_k127_5107975_24 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000002859 161.0
TH2_k127_5107975_25 dehydratase - - - 0.0000000000000000000000000000208 122.0
TH2_k127_5107975_26 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000004312 121.0
TH2_k127_5107975_27 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000001526 95.0
TH2_k127_5107975_28 Endonuclease Exonuclease Phosphatase - - - 0.0000004664 63.0
TH2_k127_5107975_29 - - - - 0.0000006305 55.0
TH2_k127_5107975_3 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 566.0
TH2_k127_5107975_4 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 521.0
TH2_k127_5107975_5 GDP-mannose 4,6 dehydratase K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 482.0
TH2_k127_5107975_6 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 437.0
TH2_k127_5107975_7 PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 438.0
TH2_k127_5107975_8 ferrochelatase activity K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 408.0
TH2_k127_5107975_9 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 368.0
TH2_k127_5208616_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1203.0
TH2_k127_5208616_1 PFAM Peptidase M16 inactive domain K07263 - - 2.936e-267 852.0
TH2_k127_5208616_10 Tetratricopeptide repeat - - - 0.00000000000000000000356 106.0
TH2_k127_5208616_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 397.0
TH2_k127_5208616_3 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 368.0
TH2_k127_5208616_4 GNAT family acetyltransferase K02348 - - 0.00000000000000000000000000000000000000000005811 164.0
TH2_k127_5208616_5 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000005887 160.0
TH2_k127_5208616_6 with chaperone activity ATP-binding subunit K03696 - - 0.0000000000000000000000000000000000000000007337 159.0
TH2_k127_5208616_7 RNase H - - - 0.00000000000000000000000000002448 122.0
TH2_k127_5208616_8 DNA-binding protein VF530 - - - 0.00000000000000000000000003667 108.0
TH2_k127_5208616_9 chaperone-mediated protein folding - - - 0.00000000000000000000004131 113.0
TH2_k127_5275100_0 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 475.0
TH2_k127_5275100_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 387.0
TH2_k127_5275100_2 COG0584 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000007729 134.0
TH2_k127_5275100_3 Protein of unknown function (DUF3307) - - - 0.000002346 54.0
TH2_k127_5309316_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 6.138e-232 726.0
TH2_k127_5309316_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 560.0
TH2_k127_5309316_2 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 306.0
TH2_k127_5309316_3 SPTR Conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001514 244.0
TH2_k127_5309316_4 shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000000000000000001515 213.0
TH2_k127_5309316_5 SPTR Conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000006267 219.0
TH2_k127_5309316_6 rod shape-determining protein MreD - - - 0.00000000000000000000000000000003217 132.0
TH2_k127_5309316_7 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000502 120.0
TH2_k127_5312952_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.109e-310 973.0
TH2_k127_5312952_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.215e-207 654.0
TH2_k127_5312952_10 Gliding motility-associated protein GldM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001019 280.0
TH2_k127_5312952_11 Gliding motility protein GldL - - - 0.0000000000000000000000000000000000000000000000000000000000000000003043 237.0
TH2_k127_5312952_12 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000008315 222.0
TH2_k127_5312952_13 gliding motility - - - 0.0000000000000000000000000000000000000000000000000000000001698 213.0
TH2_k127_5312952_14 Tetratricopeptide repeat protein - - - 0.0000000000000000000000000000000000000000000000003118 184.0
TH2_k127_5312952_15 Type IX secretion system membrane protein PorP/SprF - - - 0.000000000000000000000000000000000000000000007914 175.0
TH2_k127_5312952_16 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000000000002744 160.0
TH2_k127_5312952_17 lysyltransferase activity K07027 - - 0.0000000000000000000000000000002861 139.0
TH2_k127_5312952_18 - - - - 0.0000000000000000005285 98.0
TH2_k127_5312952_19 Preprotein translocase SecG subunit K03075 - - 0.0000000000000002858 83.0
TH2_k127_5312952_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 2.234e-202 639.0
TH2_k127_5312952_3 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 539.0
TH2_k127_5312952_4 ATPase (AAA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 524.0
TH2_k127_5312952_5 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 522.0
TH2_k127_5312952_6 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 474.0
TH2_k127_5312952_7 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 433.0
TH2_k127_5312952_8 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 377.0
TH2_k127_5312952_9 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 307.0
TH2_k127_534451_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 3.899e-320 994.0
TH2_k127_534451_1 Ultra-violet resistance protein B K03702 - - 1.426e-304 946.0
TH2_k127_534451_10 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 486.0
TH2_k127_534451_11 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 476.0
TH2_k127_534451_12 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 430.0
TH2_k127_534451_13 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 426.0
TH2_k127_534451_14 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 419.0
TH2_k127_534451_15 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 417.0
TH2_k127_534451_16 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 403.0
TH2_k127_534451_17 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 386.0
TH2_k127_534451_18 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 374.0
TH2_k127_534451_19 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 368.0
TH2_k127_534451_2 COG5337 Spore coat assembly protein - - - 1.888e-210 677.0
TH2_k127_534451_20 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 368.0
TH2_k127_534451_21 Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 366.0
TH2_k127_534451_22 Protein of unknown function (DUF2851) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 368.0
TH2_k127_534451_23 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 322.0
TH2_k127_534451_24 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 320.0
TH2_k127_534451_25 PspC domain K03973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 324.0
TH2_k127_534451_26 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 306.0
TH2_k127_534451_27 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 319.0
TH2_k127_534451_28 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 300.0
TH2_k127_534451_29 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001624 287.0
TH2_k127_534451_3 Amino acid transporter K03305 - - 8.202e-206 653.0
TH2_k127_534451_30 acetyltransferase, isoleucine patch superfamily K03818 - - 0.000000000000000000000000000000000000000000000000000000000000000000002894 239.0
TH2_k127_534451_31 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000001735 237.0
TH2_k127_534451_32 VTC domain - - - 0.000000000000000000000000000000000000000000000000000000000000104 221.0
TH2_k127_534451_33 Domain of unknown function (DUF4956) - - - 0.000000000000000000000000000000000000000000000000000000000000259 218.0
TH2_k127_534451_34 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000007771 207.0
TH2_k127_534451_35 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000009738 207.0
TH2_k127_534451_36 Abortive phage infection protein K07052 - - 0.0000000000000000000000000000000000000000000000000000001372 206.0
TH2_k127_534451_37 Putative aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000003088 203.0
TH2_k127_534451_38 ABC transporter K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000006055 196.0
TH2_k127_534451_39 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000002918 194.0
TH2_k127_534451_4 Asparagine synthase K01953 - 6.3.5.4 4.209e-198 635.0
TH2_k127_534451_40 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000003762 180.0
TH2_k127_534451_41 DUF218 domain - - - 0.000000000000000000000000000000000000000000000002284 182.0
TH2_k127_534451_42 Transcriptional regulator PadR-like family K10947 - - 0.0000000000000000000000000000000000000000001722 161.0
TH2_k127_534451_43 protein possibly involved in aromatic compounds catabolism K19222 - 3.1.2.28 0.000000000000000000000000000000000000000009191 157.0
TH2_k127_534451_44 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000001644 154.0
TH2_k127_534451_45 TPM domain - - - 0.000000000000000000000000000000000000003306 151.0
TH2_k127_534451_46 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000007978 154.0
TH2_k127_534451_47 - - - - 0.00000000000000000000009209 103.0
TH2_k127_534451_48 - - - - 0.0000000000000000000005831 104.0
TH2_k127_534451_49 Domain of unknown function (DUF1987) - - - 0.000000000000000000001003 99.0
TH2_k127_534451_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 8.777e-194 615.0
TH2_k127_534451_50 WG containing repeat - - - 0.00000000000000000007748 95.0
TH2_k127_534451_51 PFAM PspC domain - - - 0.000000000000000002043 87.0
TH2_k127_534451_52 COG3209 Rhs family protein - - - 0.000000000000000009116 89.0
TH2_k127_534451_53 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000001139 85.0
TH2_k127_534451_54 Methyltransferase - - - 0.000000000000007394 83.0
TH2_k127_534451_55 Protein of unknown function (DUF2490) - - - 0.000000009606 65.0
TH2_k127_534451_56 cell adhesion involved in biofilm formation - - - 0.00003772 55.0
TH2_k127_534451_6 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 555.0
TH2_k127_534451_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 536.0
TH2_k127_534451_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 536.0
TH2_k127_534451_9 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 523.0
TH2_k127_5391376_0 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 314.0
TH2_k127_5391376_1 PFAM Outer membrane protein, OmpA MotB, C-terminal - - - 0.00000000000000000000000000000000000004231 157.0
TH2_k127_5391376_2 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000785 111.0
TH2_k127_5443178_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1287.0
TH2_k127_5443178_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 607.0
TH2_k127_5443178_2 Participates in initiation and elongation during chromosome replication - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 512.0
TH2_k127_5443178_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 462.0
TH2_k127_5443178_4 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001189 254.0
TH2_k127_5443178_5 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000005094 174.0
TH2_k127_5443178_6 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000001476 149.0
TH2_k127_5443178_7 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000003257 156.0
TH2_k127_5443178_8 Thioredoxin - - - 0.00000000000000000000005705 103.0
TH2_k127_5483438_0 Polysulphide reductase K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 487.0
TH2_k127_5483438_1 Quinol cytochrome c oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 303.0
TH2_k127_5483438_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000001033 209.0
TH2_k127_5483438_3 cytochrome C - - - 0.000000000000000000000000000000000008724 145.0
TH2_k127_5520946_0 AsmA-like C-terminal region K07289 - - 3.738e-215 699.0
TH2_k127_5520946_1 ATPases associated with a variety of cellular activities K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 456.0
TH2_k127_5520946_10 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000004226 204.0
TH2_k127_5520946_11 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000002215 186.0
TH2_k127_5520946_12 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000002373 179.0
TH2_k127_5520946_13 Glycosyl transferase family 41 - - - 0.0000000000000000000000000001875 127.0
TH2_k127_5520946_14 Glycosyl transferases group 1 - - - 0.000000001001 70.0
TH2_k127_5520946_15 Rhamnan synthesis protein F K07272,K20444 - - 0.000000003469 67.0
TH2_k127_5520946_2 Sugar nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 364.0
TH2_k127_5520946_3 glycosyl transferase family 8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 353.0
TH2_k127_5520946_4 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 344.0
TH2_k127_5520946_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 314.0
TH2_k127_5520946_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 282.0
TH2_k127_5520946_7 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002083 280.0
TH2_k127_5520946_8 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001408 276.0
TH2_k127_5520946_9 Nucleotidyl transferase K15669 - 2.7.7.71 0.00000000000000000000000000000000000000000000000000000000000000002106 231.0
TH2_k127_5534609_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 387.0
TH2_k127_5534609_1 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000000000000000000000000002562 215.0
TH2_k127_5534609_2 C-terminal domain of CHU protein family - - - 0.000000000000000007238 98.0
TH2_k127_5534609_3 C-terminal domain of CHU protein family - - - 0.00000000001785 78.0
TH2_k127_5561252_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1752.0
TH2_k127_5561252_1 Belongs to the peptidase M16 family - - - 1.9e-322 1014.0
TH2_k127_5561252_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 388.0
TH2_k127_5561252_11 CRP FNR family transcriptional regulator K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001216 244.0
TH2_k127_5561252_12 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000001488 157.0
TH2_k127_5561252_13 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000003764 150.0
TH2_k127_5561252_14 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000002633 148.0
TH2_k127_5561252_15 Glyoxalase-like domain - - - 0.0000000000000000000000000000000003063 135.0
TH2_k127_5561252_16 - - - - 0.00000000000000000000000000000002683 129.0
TH2_k127_5561252_17 Caspase domain - - - 0.00000000000000000000000000002641 133.0
TH2_k127_5561252_18 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000009526 118.0
TH2_k127_5561252_19 DoxX K15977 - - 0.0000000000000000000000000871 111.0
TH2_k127_5561252_2 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 1.995e-201 632.0
TH2_k127_5561252_20 - - - - 0.0000000000000000000000002128 110.0
TH2_k127_5561252_21 PFAM Rhodanese-like domain - - - 0.0000000000000000000000007995 106.0
TH2_k127_5561252_22 Protein of unknown function (DUF2892) - - - 0.00000000000000002025 83.0
TH2_k127_5561252_23 Thioredoxin-like domain - - - 0.00000000000000003433 86.0
TH2_k127_5561252_24 Universal stress protein - - - 0.00000000000000399 85.0
TH2_k127_5561252_25 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000007322 73.0
TH2_k127_5561252_26 - - - - 0.00000007043 56.0
TH2_k127_5561252_27 - - - - 0.000005084 54.0
TH2_k127_5561252_28 cobalamin-transporting ATPase activity - - - 0.00003184 54.0
TH2_k127_5561252_29 - - - - 0.0001034 49.0
TH2_k127_5561252_3 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 586.0
TH2_k127_5561252_4 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 - 1.14.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 586.0
TH2_k127_5561252_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 557.0
TH2_k127_5561252_6 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 525.0
TH2_k127_5561252_7 Tryptophan 2,3-dioxygenase K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 472.0
TH2_k127_5561252_8 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 469.0
TH2_k127_5561252_9 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 442.0
TH2_k127_5602080_0 hydrolase family 92 - - - 0.0 1079.0
TH2_k127_5602080_1 Belongs to the glycosyl hydrolase 2 family K01192 - 3.2.1.25 1.569e-293 922.0
TH2_k127_5602080_10 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001033 294.0
TH2_k127_5602080_11 YeeE YedE family protein K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009809 264.0
TH2_k127_5602080_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000001125 254.0
TH2_k127_5602080_13 Participates in the control of copper homeostasis K06201 - - 0.00000000000000000000000000000000000000000000000000000000000000001636 230.0
TH2_k127_5602080_14 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000000000000000000000000000004698 202.0
TH2_k127_5602080_15 PFAM YeeE YedE family (DUF395) K07112 - - 0.0000000000000000000000000000000000000000000000001954 181.0
TH2_k127_5602080_16 TIGRFAM phenylacetate-CoA oxygenase, PaaH subunit K02610 - - 0.0000000000000000000000000000000000002754 142.0
TH2_k127_5602080_17 cellulose binding - - - 0.0000000000000000000000000006478 131.0
TH2_k127_5602080_18 - - - - 0.000000000295 69.0
TH2_k127_5602080_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 1.778e-278 869.0
TH2_k127_5602080_20 SPTR Cell surface protein K01186,K14274 - 3.2.1.18 0.000009656 59.0
TH2_k127_5602080_21 - - - - 0.0004973 50.0
TH2_k127_5602080_22 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0006332 52.0
TH2_k127_5602080_3 Pfam Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 2.337e-211 670.0
TH2_k127_5602080_4 Phenylacetate-CoA oxygenase K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 495.0
TH2_k127_5602080_5 Asparaginase K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 489.0
TH2_k127_5602080_6 COG0738 Fucose permease K02429 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 485.0
TH2_k127_5602080_7 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 403.0
TH2_k127_5602080_8 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 387.0
TH2_k127_5602080_9 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 304.0
TH2_k127_5617408_0 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 2.86e-293 924.0
TH2_k127_5617408_1 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 2.154e-252 781.0
TH2_k127_5617408_10 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000001629 232.0
TH2_k127_5617408_11 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000001859 188.0
TH2_k127_5617408_12 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000000006141 156.0
TH2_k127_5617408_13 Belongs to the ompA family K03286 - - 0.000000005269 68.0
TH2_k127_5617408_14 Metalloprotease - - - 0.00000009954 62.0
TH2_k127_5617408_15 PFAM Pregnancy-associated plasma protein-A - - - 0.000007352 58.0
TH2_k127_5617408_16 - - - - 0.0001202 53.0
TH2_k127_5617408_2 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 1.122e-218 682.0
TH2_k127_5617408_3 Glycosyltransferase, group 2 family protein K07011 - - 4.364e-214 684.0
TH2_k127_5617408_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 496.0
TH2_k127_5617408_5 PFAM Bacterial Fmu (Sun) eukaryotic nucleolar NOL1 Nop2p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 435.0
TH2_k127_5617408_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 402.0
TH2_k127_5617408_7 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 345.0
TH2_k127_5617408_8 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004735 281.0
TH2_k127_5617408_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000002215 256.0
TH2_k127_5630649_0 PFAM tRNA synthetases class I (I, L, M and V) K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 2.401e-248 776.0
TH2_k127_5630649_1 Glycosyl transferase family 2 K12984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 336.0
TH2_k127_5630649_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 320.0
TH2_k127_5656863_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 550.0
TH2_k127_5656863_1 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 447.0
TH2_k127_5656863_2 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 359.0
TH2_k127_5656863_3 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 315.0
TH2_k127_5656863_4 PFAM Uncharacterised ACR, COG1259 K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004317 263.0
TH2_k127_5656863_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000006757 262.0
TH2_k127_5656863_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009911 270.0
TH2_k127_5656863_7 Domain of unknown function (DUF4173) - - - 0.0000000000000000000000000000000000000007273 160.0
TH2_k127_5656863_8 PFAM PASTA domain K01921,K08884,K12132 - 2.7.11.1,6.3.2.4 0.000000000000000000000000000000000005044 144.0
TH2_k127_5662415_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 396.0
TH2_k127_5662415_1 TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 376.0
TH2_k127_5662415_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 374.0
TH2_k127_5662415_3 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 355.0
TH2_k127_5662415_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000006619 219.0
TH2_k127_5662415_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000002199 170.0
TH2_k127_5665071_0 Alpha-2-macroglobulin family - - - 0.0 1939.0
TH2_k127_5665071_1 B12 binding domain K00548 - 2.1.1.13 0.0 1549.0
TH2_k127_5665071_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 400.0
TH2_k127_5665071_11 Efflux ABC transporter, permease protein K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 383.0
TH2_k127_5665071_12 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 342.0
TH2_k127_5665071_13 Glycosyl transferase family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000956 342.0
TH2_k127_5665071_14 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 332.0
TH2_k127_5665071_15 ABC transporter, ATP-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 327.0
TH2_k127_5665071_16 PFAM Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 342.0
TH2_k127_5665071_17 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 346.0
TH2_k127_5665071_18 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 299.0
TH2_k127_5665071_19 Stage II sporulation protein E (SpoIIE) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003148 301.0
TH2_k127_5665071_2 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1123.0
TH2_k127_5665071_20 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000657 279.0
TH2_k127_5665071_21 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000405 282.0
TH2_k127_5665071_22 Peptidase, M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006369 280.0
TH2_k127_5665071_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004004 274.0
TH2_k127_5665071_24 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000017 244.0
TH2_k127_5665071_25 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.0000000000000000000000000000000000000000000000000000000000000000644 243.0
TH2_k127_5665071_26 outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000000000000000000000000000000003015 189.0
TH2_k127_5665071_27 - - - - 0.0000000000000000000000000000000000000000000004999 180.0
TH2_k127_5665071_28 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000001458 175.0
TH2_k127_5665071_29 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000259 153.0
TH2_k127_5665071_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1015.0
TH2_k127_5665071_30 - - - - 0.0000000000000000000000000000000002037 138.0
TH2_k127_5665071_31 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000009195 111.0
TH2_k127_5665071_32 Domain of unknown function (DUF1987) - - - 0.00000000000000000000002427 103.0
TH2_k127_5665071_33 Protein of unknown function (DUF3098) - - - 0.0000000000000000188 84.0
TH2_k127_5665071_34 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000003386 60.0
TH2_k127_5665071_35 Domain of unknown function (DUF4292) - - - 0.00000001776 65.0
TH2_k127_5665071_36 COG NOG25370 non supervised orthologous group - - - 0.000008642 52.0
TH2_k127_5665071_4 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 2.644e-251 800.0
TH2_k127_5665071_5 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 571.0
TH2_k127_5665071_6 membrane protein involved in D-alanine export K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 547.0
TH2_k127_5665071_7 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 488.0
TH2_k127_5665071_8 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 464.0
TH2_k127_5665071_9 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 416.0
TH2_k127_5709952_0 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 504.0
TH2_k127_5709952_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 452.0
TH2_k127_5709952_10 TIGRFAM FeS assembly SUF system protein - - - 0.00000000000000000000000000000000007266 136.0
TH2_k127_5709952_11 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000008958 136.0
TH2_k127_5709952_12 - - - - 0.00000000000000000000001206 110.0
TH2_k127_5709952_13 Outer membrane protein beta-barrel domain - - - 0.00000000000001098 83.0
TH2_k127_5709952_14 Reeler domain - - - 0.0000000000006799 79.0
TH2_k127_5709952_15 M6 family metalloprotease domain protein - - - 0.0005066 51.0
TH2_k127_5709952_2 Cys/Met metabolism PLP-dependent enzyme K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 456.0
TH2_k127_5709952_3 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 367.0
TH2_k127_5709952_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 290.0
TH2_k127_5709952_5 assembly protein, SufD K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002565 252.0
TH2_k127_5709952_6 Protein of unknown function (DUF2480) - - - 0.000000000000000000000000000000000000000000000000000000000000000007666 228.0
TH2_k127_5709952_7 SufE protein probably involved in Fe-S center assembly K02426 - - 0.0000000000000000000000000000000000000000000000000000000009573 203.0
TH2_k127_5709952_8 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000006407 182.0
TH2_k127_5709952_9 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000001426 167.0
TH2_k127_5786690_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1168.0
TH2_k127_5786690_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 3.836e-291 904.0
TH2_k127_5786690_10 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000003938 261.0
TH2_k127_5786690_11 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000000000000000000001919 257.0
TH2_k127_5786690_12 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000006403 239.0
TH2_k127_5786690_13 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000002878 196.0
TH2_k127_5786690_14 Protein of unknown function (Porph_ging) - - - 0.000000000000000000000000000000000000000000000000009947 189.0
TH2_k127_5786690_15 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000000001627 124.0
TH2_k127_5786690_16 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000014 122.0
TH2_k127_5786690_17 - - - - 0.0000002052 55.0
TH2_k127_5786690_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 3.528e-250 785.0
TH2_k127_5786690_3 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 597.0
TH2_k127_5786690_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 562.0
TH2_k127_5786690_5 Outer membrane protein beta-barrel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 548.0
TH2_k127_5786690_6 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 423.0
TH2_k127_5786690_7 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 412.0
TH2_k127_5786690_8 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 340.0
TH2_k127_5786690_9 succinate dehydrogenase K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001814 269.0
TH2_k127_5800238_0 Sortilin, neurotensin receptor 3, - - - 0.0 1266.0
TH2_k127_5800238_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.358e-245 781.0
TH2_k127_5800238_10 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001087 250.0
TH2_k127_5800238_11 Iron dependent repressor, metal binding and dimerisation domain K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000625 243.0
TH2_k127_5800238_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000001343 224.0
TH2_k127_5800238_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000001716 177.0
TH2_k127_5800238_14 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000007699 106.0
TH2_k127_5800238_15 Domain of unknown function (DUF4154) - - - 0.00000000000000000000002478 106.0
TH2_k127_5800238_16 YceI-like domain - - - 0.0000000000000000007352 102.0
TH2_k127_5800238_17 C-terminal domain of CHU protein family - - - 0.0000000000000003279 93.0
TH2_k127_5800238_18 - - - - 0.000000000000009145 76.0
TH2_k127_5800238_19 chaperone-mediated protein folding - - - 0.00000001167 66.0
TH2_k127_5800238_2 H( )-stimulated, divalent metal cation uptake system K03322 - - 1.636e-233 737.0
TH2_k127_5800238_20 Right handed beta helix region - - - 0.0007555 52.0
TH2_k127_5800238_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 2.54e-213 670.0
TH2_k127_5800238_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 557.0
TH2_k127_5800238_5 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 462.0
TH2_k127_5800238_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 416.0
TH2_k127_5800238_7 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 366.0
TH2_k127_5800238_8 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 378.0
TH2_k127_5800238_9 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 353.0
TH2_k127_5807192_0 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 409.0
TH2_k127_5807192_1 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 331.0
TH2_k127_5807192_2 Type IX secretion system membrane protein PorP/SprF - - - 0.000000000000000000000000000000000000000000000000000000000000000000009735 244.0
TH2_k127_5807192_3 metallopeptidase activity - - - 0.0000000000000000000000000000000000000031 155.0
TH2_k127_5807192_4 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000001674 140.0
TH2_k127_5818995_0 amino acid K03305 - - 2.339e-280 867.0
TH2_k127_5818995_1 amino acid K03305 - - 1.281e-259 806.0
TH2_k127_5818995_10 Belongs to the 'phage' integrase family - - - 0.000000006102 62.0
TH2_k127_5818995_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 478.0
TH2_k127_5818995_3 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 424.0
TH2_k127_5818995_4 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 413.0
TH2_k127_5818995_5 Thiopurine S-methyltransferase (TPMT) K00569 - 2.1.1.67 0.000000000000000000000000000000000000000000000000000000000000000000000000008409 256.0
TH2_k127_5818995_6 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000105 238.0
TH2_k127_5818995_7 - - - - 0.00000000000000000000000000001697 130.0
TH2_k127_5818995_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000001594 116.0
TH2_k127_5818995_9 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000001106 121.0
TH2_k127_5875353_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 473.0
TH2_k127_5875353_1 PFAM Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 329.0
TH2_k127_5875353_2 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 325.0
TH2_k127_5875353_3 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 299.0
TH2_k127_5875353_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001665 256.0
TH2_k127_5875353_5 cyclopropane-fatty-acyl-phospholipid synthase - - - 0.0000000000000000000000000000000000000000000000000000000004575 210.0
TH2_k127_5875353_6 WxcM-like, C-terminal - - - 0.000000000000000000000000000000000000000000000000000004038 193.0
TH2_k127_5875353_7 cellulose binding K15923 - 3.2.1.51 0.000000000000000000000000000000000000000000000001248 192.0
TH2_k127_5875353_8 Alginate lyase - - - 0.00001132 58.0
TH2_k127_5876190_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 434.0
TH2_k127_5876190_1 Conserved repeat domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 423.0
TH2_k127_5876190_2 Pyrophosphatase K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 380.0
TH2_k127_5876190_3 PFAM Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000000000000003528 134.0
TH2_k127_5876190_4 Acid phosphatase homologues - - - 0.000000000000000000000001894 111.0
TH2_k127_5876190_5 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000001907 89.0
TH2_k127_5876190_6 Immunoglobulin - - - 0.00000000005116 76.0
TH2_k127_5934106_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 586.0
TH2_k127_5934106_1 chlorophyll binding - - - 0.0000000001783 70.0
TH2_k127_5934106_2 heat shock protein binding - - - 0.0000002482 55.0
TH2_k127_5935113_0 ABC transporter transmembrane region K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 608.0
TH2_k127_5935113_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 585.0
TH2_k127_5935113_10 cellulose binding K15923 - 3.2.1.51 0.0000000000000000000000000000003739 137.0
TH2_k127_5935113_11 - - - - 0.00000000000000000006452 101.0
TH2_k127_5935113_12 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000001104 70.0
TH2_k127_5935113_13 Pkd domain containing protein K01337 - 3.4.21.50 0.0000002673 63.0
TH2_k127_5935113_14 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0003097 51.0
TH2_k127_5935113_2 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 573.0
TH2_k127_5935113_3 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 527.0
TH2_k127_5935113_4 tRNA hydroxylase K06169 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001104 278.0
TH2_k127_5935113_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002204 266.0
TH2_k127_5935113_6 Domain of unknown function (DUF1905) - - - 0.0000000000000000000000000000000000000000000000000001534 191.0
TH2_k127_5935113_7 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000003613 185.0
TH2_k127_5935113_8 Pectate lyase - - - 0.0000000000000000000000000000000000000000000000004358 195.0
TH2_k127_5935113_9 TIGRFAM endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000009958 132.0
TH2_k127_5938369_0 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 - - 1.758e-275 851.0
TH2_k127_5938369_1 Part of SUF system involved in inserting iron-sulfur clusters into proteins K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000956 409.0
TH2_k127_5938369_2 Protein of unknown function (DUF3109) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001426 243.0
TH2_k127_5938369_3 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000023 177.0
TH2_k127_5938369_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000009147 123.0
TH2_k127_5938369_5 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000008656 98.0
TH2_k127_5984618_0 ABC-type polysaccharide polyol phosphate transport system, ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 457.0
TH2_k127_5984618_1 transport, permease protein K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 325.0
TH2_k127_5984618_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004409 251.0
TH2_k127_5984618_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006231 253.0
TH2_k127_5984618_4 Chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000000007029 223.0
TH2_k127_5984618_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000703 188.0
TH2_k127_5984618_6 Transcription termination factor nusG - - - 0.00000000000000000000000000001309 124.0
TH2_k127_603919_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1121.0
TH2_k127_603919_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 464.0
TH2_k127_603919_2 PFAM Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007943 379.0
TH2_k127_603919_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 340.0
TH2_k127_603919_4 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 308.0
TH2_k127_603919_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000006547 183.0
TH2_k127_603919_6 - - - - 0.00000000000000000000000000001133 128.0
TH2_k127_603919_7 Polysaccharide deacetylase - - - 0.00000000000000000000000000002473 128.0
TH2_k127_6040395_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 551.0
TH2_k127_6040395_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 467.0
TH2_k127_6040395_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 449.0
TH2_k127_6040395_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 442.0
TH2_k127_6040395_4 Sigma-70 region 3 K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 433.0
TH2_k127_6040395_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 422.0
TH2_k127_6040395_6 Metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 300.0
TH2_k127_6040395_7 - - - - 0.0000000000000000000000000003378 129.0
TH2_k127_6040395_8 Type IX secretion system membrane protein PorP/SprF - - - 0.000000003358 58.0
TH2_k127_6171846_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 546.0
TH2_k127_6171846_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 335.0
TH2_k127_6171846_2 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 275.0
TH2_k127_6171846_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000007698 255.0
TH2_k127_6171846_4 Protein of unknown function (DUF1616) - - - 0.000000000000000000000000000000000000000000000000000001247 207.0
TH2_k127_6171846_5 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000003745 160.0
TH2_k127_6171846_6 Biotin-lipoyl like K02005 - - 0.0002543 44.0
TH2_k127_6211635_0 COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 495.0
TH2_k127_6211635_1 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 345.0
TH2_k127_6211635_2 Type IX secretion system membrane protein PorP/SprF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003228 258.0
TH2_k127_6211635_3 domain protein K13735 - - 0.000000000000000000000000000000000000000000000000001296 209.0
TH2_k127_6211635_4 Putative porin - - - 0.000000000000000000000000000001884 139.0
TH2_k127_6211635_5 Pkd domain containing protein - - - 0.00000000000000000000000064 122.0
TH2_k127_6262050_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.107e-303 945.0
TH2_k127_6262050_1 Belongs to the arginase family K01479 - 3.5.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 464.0
TH2_k127_6262050_2 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 422.0
TH2_k127_6262050_3 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 317.0
TH2_k127_6262050_4 - - - - 0.000000000000000000000000000000000000000000001323 173.0
TH2_k127_6262050_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000424 138.0
TH2_k127_6262050_6 - - - - 0.000000000000000000000002674 108.0
TH2_k127_6262050_7 YceI-like domain - - - 0.00000000000000000003299 102.0
TH2_k127_6262050_8 Domain of unknown function (DUF5103) - - - 0.0000006155 51.0
TH2_k127_6313372_0 Glycosyl hydrolase family 3 N terminal domain - - - 5.154e-313 987.0
TH2_k127_6313372_1 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 5.792e-283 885.0
TH2_k127_6313372_10 Domain of unknown function (DUF4465) - - - 0.00000000000000000000000000000000000000001078 166.0
TH2_k127_6313372_11 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000001448 60.0
TH2_k127_6313372_2 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 434.0
TH2_k127_6313372_3 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 415.0
TH2_k127_6313372_4 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 371.0
TH2_k127_6313372_5 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 334.0
TH2_k127_6313372_6 endonuclease I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006807 286.0
TH2_k127_6313372_7 PFAM Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001217 271.0
TH2_k127_6313372_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000667 274.0
TH2_k127_6313372_9 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001256 272.0
TH2_k127_6344999_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1066.0
TH2_k127_6344999_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 7.065e-259 803.0
TH2_k127_6344999_10 Pectate lyase - - - 0.0000318 57.0
TH2_k127_6344999_2 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 414.0
TH2_k127_6344999_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000003886 256.0
TH2_k127_6344999_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000002086 232.0
TH2_k127_6344999_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000539 217.0
TH2_k127_6344999_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001152 187.0
TH2_k127_6344999_7 - - - - 0.000000000000000000000000000002766 132.0
TH2_k127_6344999_8 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000003145 91.0
TH2_k127_6344999_9 - - - - 0.000000000125 68.0
TH2_k127_6600479_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000001609 175.0
TH2_k127_6600479_1 radical SAM domain protein - - - 0.00002392 56.0
TH2_k127_6609449_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.082e-275 863.0
TH2_k127_6609449_1 metallopeptidase activity K01337 - 3.4.21.50 0.0000000000000000000004243 101.0
TH2_k127_6609449_2 - - - - 0.000000000000008431 82.0
TH2_k127_6833702_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 3.445e-223 702.0
TH2_k127_6833702_1 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009784 559.0
TH2_k127_6833702_10 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001371 250.0
TH2_k127_6833702_11 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000004564 233.0
TH2_k127_6833702_12 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K15460 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.223 0.000000000000000000000000000000000000000000000000000000004091 207.0
TH2_k127_6833702_13 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000002272 209.0
TH2_k127_6833702_14 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000005642 195.0
TH2_k127_6833702_15 Type IX secretion system membrane protein PorP/SprF - - - 0.000000000000000000000000000000000000000000000000003363 194.0
TH2_k127_6833702_16 GxxExxY protein - - - 0.00000000000000000000000000000000000000000000000001033 184.0
TH2_k127_6833702_17 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000002424 200.0
TH2_k127_6833702_18 - - - - 0.0000000000000000000000000000000000000000000003289 177.0
TH2_k127_6833702_19 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000002619 171.0
TH2_k127_6833702_2 phosphohydrolase K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 504.0
TH2_k127_6833702_20 C-terminal domain of CHU protein family - - - 0.00000000000000000000000000000000000000004421 176.0
TH2_k127_6833702_21 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000003361 147.0
TH2_k127_6833702_22 Universal stress protein family - - - 0.0000000000000000009158 96.0
TH2_k127_6833702_24 - - - - 0.00008771 51.0
TH2_k127_6833702_3 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 458.0
TH2_k127_6833702_4 FMN-dependent dehydrogenase K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 458.0
TH2_k127_6833702_5 CinA-like protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 433.0
TH2_k127_6833702_6 Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 386.0
TH2_k127_6833702_7 PFAM Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 328.0
TH2_k127_6833702_8 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 316.0
TH2_k127_6833702_9 N-acetylglucosamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001379 262.0
TH2_k127_6941040_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 2.421e-314 977.0
TH2_k127_6941040_1 pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 4.851e-266 831.0
TH2_k127_6941040_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008773 276.0
TH2_k127_6941040_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001593 233.0
TH2_k127_6941040_12 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000001512 176.0
TH2_k127_6941040_13 - - - - 0.000000000000000000000000000000000000001559 152.0
TH2_k127_6941040_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000002482 149.0
TH2_k127_6941040_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000001182 146.0
TH2_k127_6941040_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000008439 138.0
TH2_k127_6941040_17 - - - - 0.0000000000000000000000000000000002659 136.0
TH2_k127_6941040_18 HEPN domain - - - 0.000000007498 62.0
TH2_k127_6941040_2 Proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 1.994e-249 785.0
TH2_k127_6941040_3 regulator - - - 2.643e-248 812.0
TH2_k127_6941040_4 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 3.809e-217 683.0
TH2_k127_6941040_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 554.0
TH2_k127_6941040_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 521.0
TH2_k127_6941040_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 518.0
TH2_k127_6941040_8 COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 445.0
TH2_k127_6941040_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005339 296.0
TH2_k127_6959421_0 Carboxypeptidase regulatory-like domain - - - 1.166e-198 645.0
TH2_k127_6959421_1 Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 576.0
TH2_k127_6959421_2 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 427.0
TH2_k127_6959421_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003766 273.0
TH2_k127_6959421_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000001712 248.0
TH2_k127_6959421_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000001691 215.0
TH2_k127_6959421_6 Thioesterase superfamily K02614 - - 0.000000000000000000000000000000000000000000738 160.0
TH2_k127_6959421_7 - - - - 0.0002198 49.0
TH2_k127_697096_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775,K01929 - 5.1.1.1,6.3.2.10 4.323e-239 763.0
TH2_k127_697096_1 PFAM Aminotransferase, class I K14287 - 2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 490.0
TH2_k127_697096_10 - - - - 0.000000001992 66.0
TH2_k127_697096_11 - - - - 0.0002055 51.0
TH2_k127_697096_2 chorismate mutase K04516 - 5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 421.0
TH2_k127_697096_3 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 285.0
TH2_k127_697096_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001212 240.0
TH2_k127_697096_5 GAF domain K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000000000000000000000003071 223.0
TH2_k127_697096_6 TIGRFAM comF family protein K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000001406 216.0
TH2_k127_697096_7 - - - - 0.00000000000000000000000000000000000000000000000000000001578 200.0
TH2_k127_697096_8 Transposase - - - 0.0000000000000000000000000000001639 136.0
TH2_k127_6983113_0 COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains - - - 3.616e-256 798.0
TH2_k127_6983113_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 499.0
TH2_k127_6983113_10 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000002328 160.0
TH2_k127_6983113_11 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000005331 143.0
TH2_k127_6983113_12 Belongs to the peptidase S8 family K20276 - - 0.000000000000000000000000000000005125 140.0
TH2_k127_6983113_13 metallopeptidase activity K01186 - 3.2.1.18 0.000000000000000001454 96.0
TH2_k127_6983113_14 PKD domain - - - 0.000000000002576 74.0
TH2_k127_6983113_16 Protein conserved in bacteria - - - 0.0000000001318 75.0
TH2_k127_6983113_17 CarboxypepD_reg-like domain - - - 0.00001387 56.0
TH2_k127_6983113_2 Tyrosine recombinase XerC K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 383.0
TH2_k127_6983113_3 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 362.0
TH2_k127_6983113_4 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 370.0
TH2_k127_6983113_5 XRE family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 314.0
TH2_k127_6983113_6 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000011 275.0
TH2_k127_6983113_7 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005431 265.0
TH2_k127_6983113_8 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000005087 207.0
TH2_k127_6983113_9 single-stranded DNA-binding protein K03111 - - 0.000000000000000000000000000000000000000008306 156.0
TH2_k127_7004432_0 UDP-N-acetylglucosamine 2-epimerase K13019 - 5.1.3.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 484.0
TH2_k127_7004432_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 445.0
TH2_k127_7004432_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 302.0
TH2_k127_7004432_3 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001235 263.0
TH2_k127_7004432_4 endonuclease containing a URI domain K07461 - - 0.000000000000000000000000006893 113.0
TH2_k127_7034898_0 RNA polymerase I subunit A N-terminus K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2226.0
TH2_k127_7034898_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2081.0
TH2_k127_7034898_10 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 362.0
TH2_k127_7034898_11 PFAM Cytochrome c assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 283.0
TH2_k127_7034898_12 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006357 273.0
TH2_k127_7034898_13 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000001578 246.0
TH2_k127_7034898_14 DNA-3-methyladenine glycosylase activity K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000003295 243.0
TH2_k127_7034898_15 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000003159 222.0
TH2_k127_7034898_16 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000004219 218.0
TH2_k127_7034898_17 Belongs to the UPF0403 family - - - 0.0000000000000000000000000000000000000000000000000000000009573 203.0
TH2_k127_7034898_18 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000003496 201.0
TH2_k127_7034898_19 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000006588 196.0
TH2_k127_7034898_2 SprB repeat - - - 0.0 1248.0
TH2_k127_7034898_20 PFAM PKD domain - - - 0.0000000000000000000000000000000000000000000000000007335 204.0
TH2_k127_7034898_21 ABC-type transport system involved in cytochrome c biogenesis permease component K02194 - - 0.00000000000000000000000000000000000000000000000001269 188.0
TH2_k127_7034898_22 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000007405 171.0
TH2_k127_7034898_23 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000001033 164.0
TH2_k127_7034898_24 Rossmann-like domain - - - 0.000000000000000000000000000000000000001374 158.0
TH2_k127_7034898_25 metallopeptidase activity - - - 0.00000000000000000000000000000000004511 158.0
TH2_k127_7034898_26 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000004817 138.0
TH2_k127_7034898_27 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000000000000002596 133.0
TH2_k127_7034898_28 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.00000000000000000000000000000009427 129.0
TH2_k127_7034898_29 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000001624 115.0
TH2_k127_7034898_3 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 5.434e-270 839.0
TH2_k127_7034898_30 - - - - 0.000000000000000000002599 101.0
TH2_k127_7034898_31 SecE/Sec61-gamma subunits of protein translocation complex K03073 - - 0.000000000000006748 76.0
TH2_k127_7034898_32 PFAM Ankyrin - - - 0.0000000000002703 78.0
TH2_k127_7034898_33 CotH kinase protein - - - 0.0000000000005681 77.0
TH2_k127_7034898_34 - - - - 0.00000000001984 66.0
TH2_k127_7034898_4 Amidophosphoribosyltransferase K00764 - 2.4.2.14 6.555e-270 843.0
TH2_k127_7034898_5 Carboxypeptidase regulatory-like domain - - - 1.165e-240 766.0
TH2_k127_7034898_6 PFAM Cytochrome c assembly protein K02198 - - 3.571e-227 732.0
TH2_k127_7034898_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 3.601e-223 695.0
TH2_k127_7034898_8 Thiol disulfide interchange protein K04084 - 1.8.1.8 2.589e-208 668.0
TH2_k127_7034898_9 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 438.0
TH2_k127_7051590_0 TonB dependent receptor - - - 1.184e-267 846.0
TH2_k127_7051590_1 PFAM Serine dehydratase alpha chain K01752 - 4.3.1.17 1.083e-228 716.0
TH2_k127_7051590_2 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 458.0
TH2_k127_7051590_3 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 422.0
TH2_k127_7051590_4 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 301.0
TH2_k127_7051590_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000007027 266.0
TH2_k127_7051590_6 Domain of unknown function (DUF4249) - - - 0.0000000000000000000000000000000000000000007824 168.0
TH2_k127_7051590_7 - - - - 0.00000000000000000000000496 112.0
TH2_k127_7051590_8 - - - - 0.00000000002485 71.0
TH2_k127_7051817_0 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000009489 183.0
TH2_k127_7051817_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000002211 113.0
TH2_k127_7051817_2 Cytochrome c - - - 0.00002496 49.0
TH2_k127_7054089_0 Belongs to the MurCDEF family K03802 - 6.3.2.29,6.3.2.30 0.0 1317.0
TH2_k127_7054089_1 ABC-type multidrug transport system ATPase and permease K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 612.0
TH2_k127_7054089_10 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007357 263.0
TH2_k127_7054089_11 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000007189 183.0
TH2_k127_7054089_12 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000007385 172.0
TH2_k127_7054089_13 Acyl carrier protein phosphodiesterase - - - 0.0000000000000000000000000000000000000000009308 163.0
TH2_k127_7054089_14 Chaperone of endosialidase - - - 0.000000000000000000000000000003765 139.0
TH2_k127_7054089_15 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000005564 116.0
TH2_k127_7054089_16 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.0000000000000000000000004053 110.0
TH2_k127_7054089_17 metallopeptidase activity K01181,K15531 GO:0005575,GO:0016020 3.2.1.156,3.2.1.8 0.00000000000000000004256 107.0
TH2_k127_7054089_18 chlorophyll binding - - - 0.00000052 57.0
TH2_k127_7054089_19 Belongs to the peptidase S8 family - - - 0.00002086 53.0
TH2_k127_7054089_2 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 622.0
TH2_k127_7054089_3 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 593.0
TH2_k127_7054089_4 DEAD DEAH box helicase domain protein K05591 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 507.0
TH2_k127_7054089_5 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 458.0
TH2_k127_7054089_6 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 407.0
TH2_k127_7054089_7 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 400.0
TH2_k127_7054089_8 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 306.0
TH2_k127_7054089_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000002121 269.0
TH2_k127_7066464_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 1.879e-219 685.0
TH2_k127_7066464_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 603.0
TH2_k127_7066464_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000002273 249.0
TH2_k127_7066464_3 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000002033 196.0
TH2_k127_7066464_4 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000000000000007043 149.0
TH2_k127_7066464_5 Pkd domain containing protein K01337 - 3.4.21.50 0.00000000000000000000000000005355 136.0
TH2_k127_7066464_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000129 87.0
TH2_k127_7066464_7 Glucose / Sorbosone dehydrogenase - - - 0.000002753 61.0
TH2_k127_7066464_8 radical SAM domain protein - - - 0.00004244 52.0
TH2_k127_7130_0 Hsp90 protein K04079 - - 1.286e-265 831.0
TH2_k127_7130_1 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 3.753e-235 741.0
TH2_k127_7130_10 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000331 171.0
TH2_k127_7130_11 FlgD Ig-like domain K21449 - - 0.000002344 59.0
TH2_k127_7130_2 PFAM peptidase M13 K07386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 597.0
TH2_k127_7130_3 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 508.0
TH2_k127_7130_4 FAD dependent oxidoreductase K15736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 497.0
TH2_k127_7130_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 464.0
TH2_k127_7130_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 346.0
TH2_k127_7130_7 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 311.0
TH2_k127_7130_8 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000004331 239.0
TH2_k127_7130_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000594 233.0
TH2_k127_719468_0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain K01585 - 4.1.1.19 3.925e-226 708.0
TH2_k127_719468_1 ABC-type multidrug transport system ATPase and permease K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 570.0
TH2_k127_719468_2 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 436.0
TH2_k127_719468_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000001862 122.0
TH2_k127_719468_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000004726 84.0
TH2_k127_7236362_0 Phenylacetic acid degradation protein PaaN K02618 - 1.2.1.91,3.3.2.12 0.0 1036.0
TH2_k127_7236362_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.389e-227 723.0
TH2_k127_7236362_10 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002605 244.0
TH2_k127_7236362_11 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008131 245.0
TH2_k127_7236362_12 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001202 248.0
TH2_k127_7236362_13 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000001561 234.0
TH2_k127_7236362_14 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000004049 212.0
TH2_k127_7236362_15 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000001168 192.0
TH2_k127_7236362_16 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K07025 - - 0.00000000000000000000000000000000000000000000000004812 186.0
TH2_k127_7236362_17 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000003242 143.0
TH2_k127_7236362_18 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000002219 127.0
TH2_k127_7236362_19 - - - - 0.0000000000006733 75.0
TH2_k127_7236362_2 ABC transporter K15738 - - 1.946e-217 691.0
TH2_k127_7236362_20 Domain of unknown function (DUF4476) - - - 0.000000000003163 75.0
TH2_k127_7236362_21 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.000000000006984 68.0
TH2_k127_7236362_22 Protein of unknown function (DUF3822) - - - 0.0000007241 60.0
TH2_k127_7236362_23 PKD domain - - - 0.0002351 53.0
TH2_k127_7236362_3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 517.0
TH2_k127_7236362_4 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 432.0
TH2_k127_7236362_5 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 428.0
TH2_k127_7236362_6 Domain of unknown function (DUF5103) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 341.0
TH2_k127_7236362_7 Stage II sporulation protein E (SpoIIE) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 339.0
TH2_k127_7236362_8 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 309.0
TH2_k127_7236362_9 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 306.0
TH2_k127_7236696_0 RQC K03654 - 3.6.4.12 5.487e-311 968.0
TH2_k127_7236696_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 451.0
TH2_k127_7236696_10 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000001089 232.0
TH2_k127_7236696_11 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000002747 244.0
TH2_k127_7236696_12 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000003423 229.0
TH2_k127_7236696_13 AhpC TSA family - - - 0.00000000000000000000000000000000000000000000000000000000121 205.0
TH2_k127_7236696_14 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000006587 184.0
TH2_k127_7236696_15 Protein of unknown function (DUF1571) - - - 0.00000000000000000000000000000000000000000003161 172.0
TH2_k127_7236696_16 -O-antigen K02847 - - 0.0000000000000000000000000000000000002682 158.0
TH2_k127_7236696_17 Sporulation related domain - - - 0.00000000000000000000000000000000002579 148.0
TH2_k127_7236696_18 - - - - 0.0000000000000000000000000000000001792 134.0
TH2_k127_7236696_19 Lipopolysaccharide-assembly, LptC-related - - - 0.00000000000000000000000000002165 124.0
TH2_k127_7236696_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 453.0
TH2_k127_7236696_20 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000004665 124.0
TH2_k127_7236696_21 Outer membrane protein Omp28 - - - 0.0000000000008039 79.0
TH2_k127_7236696_22 Shikimate K00014 - 1.1.1.25 0.00000000001125 66.0
TH2_k127_7236696_23 - - - - 0.00000000134 60.0
TH2_k127_7236696_25 - - - - 0.000005587 58.0
TH2_k127_7236696_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 398.0
TH2_k127_7236696_4 Bestrophin, RFP-TM, chloride channel K08994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 397.0
TH2_k127_7236696_5 Glycosyl transferase, family 9 K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 372.0
TH2_k127_7236696_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 364.0
TH2_k127_7236696_7 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 317.0
TH2_k127_7236696_8 Hexapeptide repeat of succinyl-transferase K02617,K08279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 312.0
TH2_k127_7236696_9 thioesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001532 236.0
TH2_k127_7254569_0 ATP-binding cassette protein, ChvD family - - - 5.958e-271 843.0
TH2_k127_7254569_1 Alanine dehydrogenase PNT, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 452.0
TH2_k127_7254569_2 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 402.0
TH2_k127_7254569_3 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 352.0
TH2_k127_7254569_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000004058 236.0
TH2_k127_7254569_5 PFAM Peptidase family S41 - - - 0.000000000000000000000000000000000000000000000000000000001646 219.0
TH2_k127_7254569_6 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000001495 106.0
TH2_k127_7254569_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000003695 91.0
TH2_k127_7261111_0 PFAM WD40-like beta Propeller - - - 1.529e-220 722.0
TH2_k127_7261111_1 amidohydrolase K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 465.0
TH2_k127_7261111_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000004435 183.0
TH2_k127_7261111_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000008316 129.0
TH2_k127_7279958_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0 1087.0
TH2_k127_7279958_1 Methyltransferase type 11 - - - 7.511e-208 652.0
TH2_k127_7279958_10 PFAM ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 369.0
TH2_k127_7279958_11 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 328.0
TH2_k127_7279958_12 tRNA processing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 344.0
TH2_k127_7279958_13 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 314.0
TH2_k127_7279958_14 Carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 303.0
TH2_k127_7279958_15 Vibrio cholerae RfbT protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001159 284.0
TH2_k127_7279958_16 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000008668 229.0
TH2_k127_7279958_17 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000009155 236.0
TH2_k127_7279958_18 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000006699 226.0
TH2_k127_7279958_19 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000008798 184.0
TH2_k127_7279958_2 PFAM Type III restriction enzyme, res subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 599.0
TH2_k127_7279958_20 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000004152 179.0
TH2_k127_7279958_21 Protein of unknown function (DUF1571) - - - 0.00000000000000000000000000000000000000003893 163.0
TH2_k127_7279958_22 Belongs to the ompA family - - - 0.000000000000000000000000000000000003452 161.0
TH2_k127_7279958_23 metallopeptidase activity - - - 0.000000000000000000004916 111.0
TH2_k127_7279958_24 Polysaccharide biosynthesis protein - - - 0.00000000000000000002865 104.0
TH2_k127_7279958_25 family 16 - - - 0.00000000000000000009416 102.0
TH2_k127_7279958_26 - - - - 0.00000000000002191 84.0
TH2_k127_7279958_27 Methyltransferase FkbM domain - - - 0.00000000000006001 81.0
TH2_k127_7279958_28 Polysaccharide deacetylase - - - 0.00000000000006529 79.0
TH2_k127_7279958_29 Cytochrome c - - - 0.000000004259 62.0
TH2_k127_7279958_3 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 490.0
TH2_k127_7279958_30 PFAM glycoside hydrolase, family 10 - - - 0.0000008503 60.0
TH2_k127_7279958_31 transport - - - 0.000006697 56.0
TH2_k127_7279958_4 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 488.0
TH2_k127_7279958_5 Pectate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 480.0
TH2_k127_7279958_6 Membrane protein involved in D-alanine export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 415.0
TH2_k127_7279958_7 PFAM Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 387.0
TH2_k127_7279958_8 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 385.0
TH2_k127_7279958_9 RmlD substrate binding domain K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 373.0
TH2_k127_7293208_0 ABC-2 type transporter - - - 0.0 1102.0
TH2_k127_7293208_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1024.0
TH2_k127_7293208_10 Immunoglobulin - - - 0.0000000000000000000000000000000000000000000000000000000000005972 240.0
TH2_k127_7293208_11 - - - - 0.0000000000000000000000000000000000000000000000000000000006925 212.0
TH2_k127_7293208_12 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000001249 200.0
TH2_k127_7293208_13 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000008429 192.0
TH2_k127_7293208_14 Ribosomal protein TL5, C-terminal domain K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000174 189.0
TH2_k127_7293208_15 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000003887 180.0
TH2_k127_7293208_16 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000009703 172.0
TH2_k127_7293208_17 - - - - 0.0000000000000000000000000000000000000000000003224 176.0
TH2_k127_7293208_18 PFAM Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000001578 144.0
TH2_k127_7293208_19 - - - - 0.000000000000000000000000000000007095 132.0
TH2_k127_7293208_2 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 3.637e-284 878.0
TH2_k127_7293208_20 C-terminal domain of CHU protein family - - - 0.000000000000000009251 100.0
TH2_k127_7293208_21 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000003769 89.0
TH2_k127_7293208_22 C-terminal domain of CHU protein family - - - 0.00000000000000009449 97.0
TH2_k127_7293208_23 C-terminal domain of CHU protein family - - - 0.000000000000003569 91.0
TH2_k127_7293208_3 Immunoglobulin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 601.0
TH2_k127_7293208_4 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 535.0
TH2_k127_7293208_5 Catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 437.0
TH2_k127_7293208_6 3-Deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 399.0
TH2_k127_7293208_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 368.0
TH2_k127_7293208_8 metallopeptidase activity K01337 - 3.4.21.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 326.0
TH2_k127_7293208_9 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002012 260.0
TH2_k127_7323383_0 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II K01835 - 5.4.2.2 3.866e-200 633.0
TH2_k127_7323383_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 601.0
TH2_k127_7323383_10 AhpC Tsa family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009278 273.0
TH2_k127_7323383_11 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002074 250.0
TH2_k127_7323383_12 acetyltransferase K00657 - 2.3.1.57 0.0000000000000000000000000000000000000000000000000001605 190.0
TH2_k127_7323383_13 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000002051 194.0
TH2_k127_7323383_14 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000000000000000000000000000000003297 149.0
TH2_k127_7323383_15 Thioredoxin - - - 0.0000000000000000000000000000000002078 137.0
TH2_k127_7323383_2 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 488.0
TH2_k127_7323383_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 460.0
TH2_k127_7323383_4 peptidyl-prolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 376.0
TH2_k127_7323383_5 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 331.0
TH2_k127_7323383_6 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 311.0
TH2_k127_7323383_7 Pseudouridine synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 308.0
TH2_k127_7323383_8 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 309.0
TH2_k127_7323383_9 Inward rectifier potassium channel K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009565 276.0
TH2_k127_7329978_0 TonB-dependent Receptor Plug Domain - - - 0.0 1337.0
TH2_k127_7329978_1 Sortilin, neurotensin receptor 3, - - - 7.895e-308 973.0
TH2_k127_7329978_10 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000003508 198.0
TH2_k127_7329978_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000001542 177.0
TH2_k127_7329978_12 - - - - 0.0000000000000000000000000000000000000000514 164.0
TH2_k127_7329978_13 Restriction endonuclease, type I, EcoRI, R subunit Type III, Res subunit, N-terminal - - - 0.00000000000000000000000000000000000001347 149.0
TH2_k127_7329978_14 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000001118 133.0
TH2_k127_7329978_15 TIGRFAM Por secretion system C-terminal sorting domain - - - 0.00004842 56.0
TH2_k127_7329978_16 Peptide-N-glycosidase F, C terminal - - - 0.0003394 53.0
TH2_k127_7329978_2 COGs COG3023 Negative regulator of beta-lactamase expression - - - 2.625e-280 893.0
TH2_k127_7329978_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 464.0
TH2_k127_7329978_4 TIGRFAM AMP nucleosidase K01241 - 3.2.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 411.0
TH2_k127_7329978_5 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 405.0
TH2_k127_7329978_6 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 383.0
TH2_k127_7329978_7 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 354.0
TH2_k127_7329978_8 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 304.0
TH2_k127_7329978_9 Type IX secretion system membrane protein PorP/SprF - - - 0.000000000000000000000000000000000000000000000000000002667 204.0
TH2_k127_7426026_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 9.642e-320 998.0
TH2_k127_7426026_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 3.698e-240 757.0
TH2_k127_7426026_10 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 506.0
TH2_k127_7426026_11 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 494.0
TH2_k127_7426026_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 450.0
TH2_k127_7426026_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 424.0
TH2_k127_7426026_14 MORN repeat variant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 376.0
TH2_k127_7426026_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 312.0
TH2_k127_7426026_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001228 264.0
TH2_k127_7426026_17 NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000647 224.0
TH2_k127_7426026_18 sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000163 189.0
TH2_k127_7426026_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000001057 179.0
TH2_k127_7426026_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 3.096e-224 701.0
TH2_k127_7426026_20 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000006345 177.0
TH2_k127_7426026_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000001324 164.0
TH2_k127_7426026_22 Acyltransferase family - - - 0.0000000000000000000000000000000000000002934 162.0
TH2_k127_7426026_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000007608 130.0
TH2_k127_7426026_24 OmpA family - - - 0.00000000000000000000000000001831 129.0
TH2_k127_7426026_25 - - - - 0.0000000000000000000000000004328 119.0
TH2_k127_7426026_26 C-terminal domain of CHU protein family - - - 0.000003517 61.0
TH2_k127_7426026_3 COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family - - - 1.03e-212 666.0
TH2_k127_7426026_4 Hep Hag repeat protein - - - 3.263e-208 685.0
TH2_k127_7426026_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 4.372e-208 652.0
TH2_k127_7426026_6 Psort location Cytoplasmic, score 8.96 - - - 1.629e-204 654.0
TH2_k127_7426026_7 PFAM metallophosphoesterase - - - 1.984e-194 623.0
TH2_k127_7426026_8 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 586.0
TH2_k127_7426026_9 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 511.0
TH2_k127_7448080_0 of ABC transporters with duplicated ATPase K06158 - - 6.091e-214 681.0
TH2_k127_7448080_1 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 608.0
TH2_k127_7448080_10 DUF218 domain - - - 0.000000000000000000000000000000000000000004523 162.0
TH2_k127_7448080_11 Protein of unknown function (DUF2795) - - - 0.00000000000000000000000000000000000001141 145.0
TH2_k127_7448080_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000003892 125.0
TH2_k127_7448080_13 PHP domain protein - - - 0.000000000000000000000000002747 126.0
TH2_k127_7448080_14 endonuclease containing a URI domain K07461 - - 0.000000000000000000000000005842 113.0
TH2_k127_7448080_15 Domain of unknown function (DUF4173) - - - 0.00000000000000000000001158 117.0
TH2_k127_7448080_16 Leucine-rich repeats, outliers K13730 - - 0.00000000000000000007248 104.0
TH2_k127_7448080_17 amine dehydrogenase activity - - - 0.0000000001447 73.0
TH2_k127_7448080_18 - - - - 0.000000001443 68.0
TH2_k127_7448080_2 Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 564.0
TH2_k127_7448080_3 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 479.0
TH2_k127_7448080_4 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 453.0
TH2_k127_7448080_5 Endonuclease exonuclease phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 355.0
TH2_k127_7448080_6 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 287.0
TH2_k127_7448080_7 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000005099 196.0
TH2_k127_7448080_8 Transposase - - - 0.000000000000000000000000000000000000000000000000001087 193.0
TH2_k127_7448080_9 - - - - 0.000000000000000000000000000000000000000003624 170.0
TH2_k127_7449468_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1435.0
TH2_k127_7449468_1 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.539e-260 809.0
TH2_k127_7449468_10 lipoprotein biosynthetic process K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 319.0
TH2_k127_7449468_11 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000023 288.0
TH2_k127_7449468_12 1-aminocyclopropane-1-carboxylate deaminase K01505 - 3.5.99.7 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 265.0
TH2_k127_7449468_13 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004751 262.0
TH2_k127_7449468_14 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001516 260.0
TH2_k127_7449468_15 glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000211 256.0
TH2_k127_7449468_16 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000001425 233.0
TH2_k127_7449468_17 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000002429 222.0
TH2_k127_7449468_18 Belongs to the sigma-70 factor family - - - 0.0000000000000000000000000000000000000000000000000002297 192.0
TH2_k127_7449468_19 YCII-related domain - - - 0.000000000000000000000000000000000000000000000001125 177.0
TH2_k127_7449468_2 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 2.82e-238 743.0
TH2_k127_7449468_20 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000009838 171.0
TH2_k127_7449468_21 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000008007 108.0
TH2_k127_7449468_22 NifU domain protein - - - 0.000000000000000000000002885 103.0
TH2_k127_7449468_23 - - - - 0.000000001909 68.0
TH2_k127_7449468_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 574.0
TH2_k127_7449468_4 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 564.0
TH2_k127_7449468_5 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 464.0
TH2_k127_7449468_6 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008171 487.0
TH2_k127_7449468_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 439.0
TH2_k127_7449468_8 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573,K12585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 397.0
TH2_k127_7449468_9 apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 381.0
TH2_k127_7483748_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1137.0
TH2_k127_7483748_1 Aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 3.999e-242 755.0
TH2_k127_7483748_10 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 519.0
TH2_k127_7483748_11 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 476.0
TH2_k127_7483748_12 DeoC/LacD family aldolase K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 423.0
TH2_k127_7483748_13 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 365.0
TH2_k127_7483748_14 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 363.0
TH2_k127_7483748_15 Belongs to the GPAT DAPAT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 335.0
TH2_k127_7483748_16 Psort location CytoplasmicMembrane, score 10.00 K12343 - 1.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 272.0
TH2_k127_7483748_17 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000001078 239.0
TH2_k127_7483748_18 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000002083 235.0
TH2_k127_7483748_19 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000005122 247.0
TH2_k127_7483748_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 4.33e-209 658.0
TH2_k127_7483748_20 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000008981 229.0
TH2_k127_7483748_21 Glyco_18 - - - 0.0000000000000000000000000000000000000000000000000000000000001203 235.0
TH2_k127_7483748_22 Belongs to the BI1 family K06890 - - 0.00000000000000000000000000000000000000000000000000000000001199 215.0
TH2_k127_7483748_23 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000000003963 214.0
TH2_k127_7483748_24 Catalyzes the synthesis of activated sulfate K00860 GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 0.00000000000000000000000000000000000000000000000000409 186.0
TH2_k127_7483748_25 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000008331 195.0
TH2_k127_7483748_26 - - - - 0.00000000000000000000000000000000000000005337 159.0
TH2_k127_7483748_27 - - - - 0.00000000000000000000000000000000000004504 153.0
TH2_k127_7483748_28 Putative quorum-sensing-regulated virulence factor K09954 - - 0.00000000000000000000000001488 109.0
TH2_k127_7483748_29 Protein of unknown function (DUF983) - - - 0.0000000000000000000000003078 110.0
TH2_k127_7483748_3 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member - - - 5.182e-208 671.0
TH2_k127_7483748_30 Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. - - - 0.0000000000000000000001249 113.0
TH2_k127_7483748_31 - - - - 0.00000000000000000001939 97.0
TH2_k127_7483748_32 Ribonuclease P K03536 - 3.1.26.5 0.0000000000000000001476 92.0
TH2_k127_7483748_33 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000005211 74.0
TH2_k127_7483748_34 - - - - 0.000000000006789 70.0
TH2_k127_7483748_35 Transcriptional regulatory protein, C terminal - - - 0.000000000007042 70.0
TH2_k127_7483748_36 - - - - 0.000000007952 59.0
TH2_k127_7483748_37 resolvase domain - - - 0.000001995 50.0
TH2_k127_7483748_38 30S ribosomal protein Thx - - - 0.0004082 44.0
TH2_k127_7483748_4 Cys/Met metabolism PLP-dependent enzyme K19715 - 2.6.1.109 1.219e-196 619.0
TH2_k127_7483748_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 593.0
TH2_k127_7483748_6 Iron-containing alcohol dehydrogenase K19714 - 1.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 587.0
TH2_k127_7483748_7 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 587.0
TH2_k127_7483748_8 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 574.0
TH2_k127_7483748_9 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 535.0
TH2_k127_7568101_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000008149 192.0
TH2_k127_7568101_1 Chaperone of endosialidase - - - 0.0000000000000000000000000000000000004263 163.0
TH2_k127_7568101_2 PFAM Outer membrane protein, OmpA MotB, C-terminal - - - 0.0000000000000000000000000000002072 136.0
TH2_k127_7568101_3 C-terminal domain of CHU protein family - - - 0.0000000000000000000000012 115.0
TH2_k127_7568101_4 - - - - 0.000002281 53.0
TH2_k127_7651537_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 550.0
TH2_k127_7651537_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 451.0
TH2_k127_7651537_2 Domain of unknown function (DUF4835) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 312.0
TH2_k127_7651537_3 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 317.0
TH2_k127_7651537_4 outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000000000000000000000000000000000000000000000003344 211.0
TH2_k127_7651537_5 Stage II sporulation protein E (SpoIIE) - - - 0.00000000000000000000000000000000000000000000007397 173.0
TH2_k127_7651537_6 RNA polymerase Rpb6 - - - 0.000000000000000000000000000000000000001558 149.0
TH2_k127_7677500_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 3.682e-194 612.0
TH2_k127_7677500_1 Fumarylacetoacetase K01555 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 590.0
TH2_k127_7677500_10 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000007788 180.0
TH2_k127_7677500_11 pfam nudix - - - 0.00000000000000000000000000000000000000001238 161.0
TH2_k127_7677500_12 polygalacturonase activity K01083 - 3.1.3.8 0.0000000000000000000001364 114.0
TH2_k127_7677500_14 amine dehydrogenase activity K20276 - - 0.00000000000000000002023 107.0
TH2_k127_7677500_15 PFAM KWG Leptospira - - - 0.0000000000000001074 93.0
TH2_k127_7677500_16 Methyltransferase domain - - - 0.00000004907 63.0
TH2_k127_7677500_17 - - - - 0.0000005689 59.0
TH2_k127_7677500_18 membrane - - - 0.000006976 50.0
TH2_k127_7677500_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 556.0
TH2_k127_7677500_3 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 465.0
TH2_k127_7677500_4 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 449.0
TH2_k127_7677500_5 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 387.0
TH2_k127_7677500_6 glyoxalase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000168 265.0
TH2_k127_7677500_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001652 244.0
TH2_k127_7677500_8 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000001148 199.0
TH2_k127_7677500_9 OmpA family - - - 0.00000000000000000000000000000000000000000000000000203 198.0
TH2_k127_7834861_0 PFAM Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 1.105e-313 968.0
TH2_k127_7834861_1 4Fe-4S dicluster domain K00184 - - 4.666e-307 975.0
TH2_k127_7834861_10 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000001396 98.0
TH2_k127_7834861_11 DltD protein K03740 - - 0.0000000000000000009486 99.0
TH2_k127_7834861_12 Phosphopantetheine attachment site - - - 0.00008419 48.0
TH2_k127_7834861_2 Belongs to the aldehyde dehydrogenase family K00128,K10217 - 1.2.1.3,1.2.1.32,1.2.1.85 4.572e-237 740.0
TH2_k127_7834861_3 Polysulphide reductase K00185 - - 1.305e-228 715.0
TH2_k127_7834861_4 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 482.0
TH2_k127_7834861_5 Quinol cytochrome c oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 389.0
TH2_k127_7834861_6 PFAM Class III cytochrome C family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 337.0
TH2_k127_7834861_7 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 324.0
TH2_k127_7834861_8 membrane - - - 0.0000000000000000000000000000000000000000000000000000000007629 206.0
TH2_k127_7834861_9 PFAM Cytochrome C - - - 0.000000000000000000000000000000000000002386 154.0
TH2_k127_7894279_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0 1043.0
TH2_k127_7894279_1 Peptidase, family M20 M25 M40 - - - 1.64e-233 729.0
TH2_k127_7894279_10 Thermolysin metallopeptidase, catalytic domain K01400 - 3.4.24.28 0.00001716 56.0
TH2_k127_7894279_2 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 511.0
TH2_k127_7894279_3 PFAM von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 359.0
TH2_k127_7894279_4 C-terminal domain of CHU protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001807 272.0
TH2_k127_7894279_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000135 72.0
TH2_k127_7894279_6 Peptide-N-glycosidase F, C terminal - - - 0.0000001506 63.0
TH2_k127_7894279_8 prohibitin homologues K04088 - - 0.000003965 49.0
TH2_k127_7894279_9 regulation of response to stimulus K01051,K01399,K08604,K10297,K15125 GO:0005575,GO:0005576 3.1.1.11,3.4.24.25,3.4.24.26 0.000004166 56.0
TH2_k127_7975976_0 Glycoside hydrolase family 24 - - - 2.779e-248 806.0
TH2_k127_7975976_1 PFAM GH3 auxin-responsive promoter - - - 2.665e-196 623.0
TH2_k127_7975976_10 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000000000004338 206.0
TH2_k127_7975976_11 amino acid K03294 - - 0.00000000000000000000000000000000000000001381 156.0
TH2_k127_7975976_12 Putative ATP-dependant zinc protease - - - 0.00000000000000000000000000000000001697 141.0
TH2_k127_7975976_13 - - - - 0.00000000000000000000000000000194 130.0
TH2_k127_7975976_14 Protein conserved in bacteria - - - 0.00002489 53.0
TH2_k127_7975976_15 Family of unknown function (DUF1028) K01771 - 4.6.1.13 0.0001385 46.0
TH2_k127_7975976_2 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 577.0
TH2_k127_7975976_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 542.0
TH2_k127_7975976_4 Prokaryotic glutathione synthetase, ATP-grasp domain K05844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 422.0
TH2_k127_7975976_5 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 377.0
TH2_k127_7975976_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 349.0
TH2_k127_7975976_7 PFAM 2Fe-2S iron-sulfur cluster binding domain K02613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 326.0
TH2_k127_7975976_8 PFAM Succinylglutamate desuccinylase Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 312.0
TH2_k127_7975976_9 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002013 252.0
TH2_k127_8115280_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1601.0
TH2_k127_8115280_1 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 438.0
TH2_k127_8115280_2 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005961 282.0
TH2_k127_8115280_3 - - - - 0.00000000005278 72.0
TH2_k127_8182970_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 514.0
TH2_k127_8182970_1 Aminopeptidase K01372 - 3.4.22.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 446.0
TH2_k127_8182970_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 399.0
TH2_k127_8182970_3 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000007872 184.0
TH2_k127_8182970_4 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000007194 131.0
TH2_k127_8182970_5 Biopolymer transporter ExbD K03559 - - 0.000000000000000000000000000001122 125.0
TH2_k127_8182970_6 energy transducer activity K03832 - - 0.000000000000000000000000000006685 129.0
TH2_k127_8182970_7 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.000000000000000000000000001309 120.0
TH2_k127_8182970_8 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000000000005079 68.0
TH2_k127_8182970_9 TonB family domain protein - - - 0.000000003016 68.0
TH2_k127_81871_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 537.0
TH2_k127_81871_1 Hydrolase Nlp P60 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001439 273.0
TH2_k127_81871_2 phosphoserine phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000007231 211.0
TH2_k127_81871_3 AAA domain - - - 0.00000000000000000000009731 102.0
TH2_k127_8292978_0 Subtilase family - - - 1.223e-257 836.0
TH2_k127_8292978_1 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 309.0
TH2_k127_8292978_2 cellulase activity - - - 0.000000000000000000000000000001297 130.0
TH2_k127_8299679_0 Sigma factor PP2C-like phosphatases - - - 5.558e-205 677.0
TH2_k127_8299679_1 PFAM Peptidase family M1 K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 503.0
TH2_k127_8299679_2 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 404.0
TH2_k127_8299679_3 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00123,K18332 - 1.12.1.3,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000001311 229.0
TH2_k127_8299679_4 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000007446 196.0
TH2_k127_8299679_5 epimerase - - - 0.00000000000000000000000000000000000000000000000007645 184.0
TH2_k127_8299679_6 Haem-binding domain - - - 0.000000000000000000000000000000000000000009676 158.0
TH2_k127_8427563_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 1.084e-285 887.0
TH2_k127_8427563_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.111e-257 803.0
TH2_k127_8427563_10 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000000000004539 198.0
TH2_k127_8427563_11 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000008027 199.0
TH2_k127_8427563_12 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000001485 188.0
TH2_k127_8427563_13 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000003463 192.0
TH2_k127_8427563_14 protein affecting Mg2 Co2 transport K06195 - - 0.000000000000000000000000000000000000001418 151.0
TH2_k127_8427563_15 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000005787 133.0
TH2_k127_8427563_16 small membrane protein - - - 0.00000000000000000000000002878 113.0
TH2_k127_8427563_17 Glycosyltransferase like family 2 - - - 0.0000000000000000000000005071 114.0
TH2_k127_8427563_18 Trypsin - - - 0.000000000000009715 86.0
TH2_k127_8427563_19 Acetyltransferase (GNAT) domain - - - 0.000000000009273 75.0
TH2_k127_8427563_2 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 1.721e-207 660.0
TH2_k127_8427563_20 Domain of unknown function (DUF4476) - - - 0.0000003048 62.0
TH2_k127_8427563_21 Spondin_N - - - 0.000007753 57.0
TH2_k127_8427563_3 Cysteine desulfurase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 523.0
TH2_k127_8427563_4 Saccharopine dehydrogenase K00290,K00293 - 1.5.1.10,1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 476.0
TH2_k127_8427563_5 Membrane protease subunits, stomatin prohibitin homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 435.0
TH2_k127_8427563_6 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 375.0
TH2_k127_8427563_7 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 334.0
TH2_k127_8427563_8 (2R)-phospho-3-sulfolactate synthase (ComA) K08097 - 4.4.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 326.0
TH2_k127_8427563_9 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000369 258.0
TH2_k127_8773069_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 1.303e-196 621.0
TH2_k127_8773069_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000007285 211.0
TH2_k127_8773069_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000001433 122.0
TH2_k127_8840319_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 569.0
TH2_k127_8840319_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 449.0
TH2_k127_8840319_10 Divergent 4Fe-4S mono-cluster - - - 0.00000000000000000000008991 99.0
TH2_k127_8840319_11 Two component regulator propeller - - - 0.00000000000000000008091 106.0
TH2_k127_8840319_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 388.0
TH2_k127_8840319_3 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 332.0
TH2_k127_8840319_4 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 310.0
TH2_k127_8840319_5 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 296.0
TH2_k127_8840319_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003826 252.0
TH2_k127_8840319_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000003046 231.0
TH2_k127_8840319_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000003206 157.0
TH2_k127_8840319_9 - - - - 0.0000000000000000000000001133 111.0
TH2_k127_8856831_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 583.0
TH2_k127_8856831_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 495.0
TH2_k127_8856831_10 Outer membrane protein Omp28 - - - 0.000000000001379 77.0
TH2_k127_8856831_2 enoyl-CoA hydratase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 402.0
TH2_k127_8856831_3 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 323.0
TH2_k127_8856831_4 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 316.0
TH2_k127_8856831_5 Shikimate K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000002775 266.0
TH2_k127_8856831_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000007252 200.0
TH2_k127_8856831_7 Bacterial Ig-like domain (group 3) - - - 0.000000000000000000000000000000000000000000000008386 188.0
TH2_k127_8856831_8 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000002974 174.0
TH2_k127_8856831_9 regulation of response to stimulus - - - 0.0000000000000000000003187 106.0
TH2_k127_8870870_0 of the AAA class - - - 9.624e-277 876.0
TH2_k127_8870870_1 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 403.0
TH2_k127_8870870_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 355.0
TH2_k127_8870870_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004166 241.0
TH2_k127_8870870_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000007257 244.0
TH2_k127_8870870_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003741 237.0
TH2_k127_8870870_6 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000623 151.0
TH2_k127_8870870_7 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000001483 114.0
TH2_k127_8870870_8 transferase activity, transferring amino-acyl groups - - - 0.0000000000000000000001436 108.0
TH2_k127_8870870_9 ubiE/COQ5 methyltransferase family - - - 0.000000000000002892 79.0
TH2_k127_918476_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 462.0
TH2_k127_918476_1 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 353.0
TH2_k127_918476_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000004841 118.0
TH2_k127_918476_2 COGs COG4591 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 321.0
TH2_k127_918476_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 298.0
TH2_k127_918476_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000832 270.0
TH2_k127_918476_5 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003809 241.0
TH2_k127_918476_6 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000003111 205.0
TH2_k127_918476_7 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000001249 199.0
TH2_k127_918476_8 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000494 166.0
TH2_k127_918476_9 TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000003848 170.0
TH2_k127_978202_0 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 439.0
TH2_k127_978202_1 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 424.0
TH2_k127_978202_11 - - - - 0.000000000000000001251 91.0
TH2_k127_978202_12 Psort location OuterMembrane, score - - - 0.000000007555 67.0
TH2_k127_978202_13 - - - - 0.00026 51.0
TH2_k127_978202_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 387.0
TH2_k127_978202_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 372.0
TH2_k127_978202_4 zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003353 283.0
TH2_k127_978202_5 cellulase activity K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004647 287.0
TH2_k127_978202_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000004611 274.0
TH2_k127_978202_7 PFAM O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000004591 258.0
TH2_k127_978202_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000004968 238.0
TH2_k127_978202_9 - - - - 0.000000000000000000000000000000001299 137.0