Overview

ID MAG03919
Name TH2_bin.57
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Nitrospiria
Order Nitrospirales
Family Nitrospiraceae
Genus Nitrospira_D
Species
Assembly information
Completeness (%) 91.95
Contamination (%) 6.9
GC content (%) 58.0
N50 (bp) 7,378
Genome size (bp) 3,229,718

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2916

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1005111_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002937 250.0
TH2_k127_1005111_1 - - - - 0.000000000000000000008455 100.0
TH2_k127_1078746_0 protein secretion by the type I secretion system K11004 - - 6.112e-239 744.0
TH2_k127_1078746_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022,K11003,K12532 - - 1.474e-200 635.0
TH2_k127_1078746_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 451.0
TH2_k127_1082927_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 488.0
TH2_k127_1087477_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1543.0
TH2_k127_1087477_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 4.269e-277 860.0
TH2_k127_1087477_10 4 iron, 4 sulfur cluster binding K02573 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008385 276.0
TH2_k127_1087477_11 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000002602 241.0
TH2_k127_1087477_12 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000000000000002698 157.0
TH2_k127_1087477_13 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000007406 100.0
TH2_k127_1087477_2 - - - - 2.072e-206 643.0
TH2_k127_1087477_3 phosphorelay signal transduction system - - - 3.901e-202 639.0
TH2_k127_1087477_4 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 1.489e-201 628.0
TH2_k127_1087477_5 anaphase-promoting complex binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 608.0
TH2_k127_1087477_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 555.0
TH2_k127_1087477_7 protein complex oligomerization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 536.0
TH2_k127_1087477_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 480.0
TH2_k127_1087477_9 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 453.0
TH2_k127_1097838_0 Elongation factor G, domain IV K02355 - - 1.048e-196 635.0
TH2_k127_1097838_1 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 484.0
TH2_k127_1097838_2 RadC-like JAB domain K03630 - - 0.000000000000000000000000002013 112.0
TH2_k127_1119035_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 467.0
TH2_k127_1119035_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005787 262.0
TH2_k127_1119035_2 phosphate binding protein K02040 - - 0.0000000000000000000000005294 113.0
TH2_k127_1123797_0 Arsenical pump membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 434.0
TH2_k127_1123797_1 lipid binding K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001265 268.0
TH2_k127_1123797_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000003391 232.0
TH2_k127_1123797_3 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000002816 117.0
TH2_k127_1129126_0 Type II/IV secretion system protein K02454,K02652 - - 0.0 1234.0
TH2_k127_1129126_1 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 542.0
TH2_k127_1129126_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 306.0
TH2_k127_1129126_3 domain protein K02004,K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000003218 236.0
TH2_k127_1136371_0 Formate--tetrahydrofolate ligase K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 5.045e-276 857.0
TH2_k127_1136371_1 stress-induced mitochondrial fusion K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 550.0
TH2_k127_1136371_2 stress-induced mitochondrial fusion K04087 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 477.0
TH2_k127_1136371_3 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 438.0
TH2_k127_1136371_4 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000008302 224.0
TH2_k127_1136371_5 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000001986 181.0
TH2_k127_1136371_6 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000006611 179.0
TH2_k127_1136371_7 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000002465 132.0
TH2_k127_1136371_8 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000009198 109.0
TH2_k127_1147294_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 389.0
TH2_k127_1147294_1 sialic acid-specific 9-O-acetylesterase K05970 - 3.1.1.53 0.0000000000000000000000000000000000000000000000000001136 199.0
TH2_k127_1175467_0 glycerophosphoryl diester phosphodiesterase K01113,K01126 - 3.1.3.1,3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000004693 278.0
TH2_k127_1175467_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000587 224.0
TH2_k127_1175467_2 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000001471 216.0
TH2_k127_119232_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.31e-239 742.0
TH2_k127_119232_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 567.0
TH2_k127_1194855_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.4e-269 834.0
TH2_k127_1194855_1 'glutamate synthase K00528,K03388 - 1.18.1.2,1.19.1.1,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.368e-234 730.0
TH2_k127_1194855_2 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 8.078e-207 647.0
TH2_k127_1194855_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000004787 218.0
TH2_k127_1204355_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1343.0
TH2_k127_1204355_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 3.852e-313 968.0
TH2_k127_1204355_10 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 472.0
TH2_k127_1204355_11 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 429.0
TH2_k127_1204355_12 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 414.0
TH2_k127_1204355_13 FMN binding K19339,K19343 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 400.0
TH2_k127_1204355_14 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 384.0
TH2_k127_1204355_15 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 366.0
TH2_k127_1204355_16 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 355.0
TH2_k127_1204355_17 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 328.0
TH2_k127_1204355_18 shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 323.0
TH2_k127_1204355_19 - K12065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 316.0
TH2_k127_1204355_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.133e-283 875.0
TH2_k127_1204355_20 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 307.0
TH2_k127_1204355_22 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 291.0
TH2_k127_1204355_23 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000000003043 217.0
TH2_k127_1204355_24 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000001171 210.0
TH2_k127_1204355_25 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000002962 182.0
TH2_k127_1204355_26 Ribonuclease E/G family K08301 - - 0.00000000000000000000000000000000000000000000001841 173.0
TH2_k127_1204355_27 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000002719 152.0
TH2_k127_1204355_29 Protein of unknown function (DUF2905) - - - 0.0000000000000000000003889 99.0
TH2_k127_1204355_3 Ribonuclease E/G family K08301 - - 8.474e-218 679.0
TH2_k127_1204355_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 5.96e-208 648.0
TH2_k127_1204355_5 Actin K03569 - - 6.034e-207 646.0
TH2_k127_1204355_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 5.752e-194 609.0
TH2_k127_1204355_7 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 597.0
TH2_k127_1204355_8 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 562.0
TH2_k127_1204355_9 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 483.0
TH2_k127_1208787_0 transcription factor binding K02584,K12146,K15836 - - 5.842e-254 800.0
TH2_k127_1208787_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 3.947e-245 763.0
TH2_k127_1208787_10 denitrification pathway K02569,K03532,K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 403.0
TH2_k127_1208787_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 379.0
TH2_k127_1208787_12 Evidence 2b Function of strongly homologous gene K02003,K09810,K09814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 364.0
TH2_k127_1208787_13 2OG-Fe(II) oxygenase superfamily K07394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 341.0
TH2_k127_1208787_14 Mo-molybdopterin cofactor metabolic process K03750,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007121 271.0
TH2_k127_1208787_16 RNA recognition motif - - - 0.000000000000000000000000000000000000000000005407 166.0
TH2_k127_1208787_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000224 149.0
TH2_k127_1208787_18 Response regulator, receiver - - - 0.0000000000000000000000000000003404 130.0
TH2_k127_1208787_2 Trypsin K04771 - 3.4.21.107 7.192e-228 716.0
TH2_k127_1208787_20 transferase activity, transferring glycosyl groups - - - 0.000000000002206 71.0
TH2_k127_1208787_3 efflux transmembrane transporter activity K02004 - - 7.722e-208 654.0
TH2_k127_1208787_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 3.035e-198 622.0
TH2_k127_1208787_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 484.0
TH2_k127_1208787_6 actin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 484.0
TH2_k127_1208787_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 442.0
TH2_k127_1208787_8 Evidence 5 No homology to any previously reported sequences K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 444.0
TH2_k127_1208787_9 macromolecule localization K01421,K01992,K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 421.0
TH2_k127_1210425_0 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000002184 192.0
TH2_k127_1210425_1 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000000000000000000000000004424 168.0
TH2_k127_1210425_2 UDP-N-acetylglucosamine 2-epimerase activity - - - 0.00000001505 67.0
TH2_k127_1210425_3 Cytidylyltransferase K00983 - 2.7.7.43 0.00000111 51.0
TH2_k127_1220108_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.342e-255 793.0
TH2_k127_1220108_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 1.207e-200 630.0
TH2_k127_1220108_10 Lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 351.0
TH2_k127_1220108_11 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 357.0
TH2_k127_1220108_12 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 317.0
TH2_k127_1220108_13 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 314.0
TH2_k127_1220108_14 antisigma factor binding K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 303.0
TH2_k127_1220108_15 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 302.0
TH2_k127_1220108_16 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 295.0
TH2_k127_1220108_17 energy transducer activity K03407,K03832 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000002675 255.0
TH2_k127_1220108_18 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000003835 237.0
TH2_k127_1220108_19 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000001061 228.0
TH2_k127_1220108_2 alcohol dehydrogenase K00060,K07777 - 1.1.1.103,2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 585.0
TH2_k127_1220108_20 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000002383 213.0
TH2_k127_1220108_21 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000003707 220.0
TH2_k127_1220108_22 pteridine-dependent deoxygenase K18240 - 4.1.3.40,4.1.3.45 0.0000000000000000000000000000000000000000000000000000000000611 217.0
TH2_k127_1220108_23 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.00000000000000000000000000000000003601 148.0
TH2_k127_1220108_24 dehydratase - - - 0.0000000000000000000000000000006932 129.0
TH2_k127_1220108_25 - - - - 0.00000000000000000000000000006554 121.0
TH2_k127_1220108_26 Outer membrane lipoprotein carrier protein LolA - - - 0.000000000000000000000005965 110.0
TH2_k127_1220108_27 acyl carrier protein K02078 - - 0.00000000000000000000007083 101.0
TH2_k127_1220108_28 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000001879 97.0
TH2_k127_1220108_29 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.0000000000000002677 87.0
TH2_k127_1220108_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 506.0
TH2_k127_1220108_30 xylanase chitin deacetylase K22278 - 3.5.1.104 0.000000000000002201 87.0
TH2_k127_1220108_31 AMP-binding enzyme - - - 0.0000000000001194 75.0
TH2_k127_1220108_33 - - - - 0.00006198 49.0
TH2_k127_1220108_4 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 519.0
TH2_k127_1220108_5 MMPL family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 501.0
TH2_k127_1220108_6 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 459.0
TH2_k127_1220108_7 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 443.0
TH2_k127_1220108_8 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 429.0
TH2_k127_1220108_9 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 396.0
TH2_k127_123681_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 7.855e-284 880.0
TH2_k127_123681_1 ATP:ADP antiporter activity K03301 - - 2.566e-205 646.0
TH2_k127_123681_10 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 353.0
TH2_k127_123681_11 nucleotidyltransferase activity K17882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 336.0
TH2_k127_123681_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.000000000000000000000000000000000000000000000000000000000000000000001227 240.0
TH2_k127_123681_13 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001961 241.0
TH2_k127_123681_14 Rhodanese-like domain - - - 0.000000000000000000000000000000000000000000000000000000000001033 211.0
TH2_k127_123681_15 RNA recognition motif - - - 0.000000000000000000000000000000000000000000008661 167.0
TH2_k127_123681_16 belongs to the thioredoxin family K00384,K03671 - 1.8.1.9 0.000000000000000000000000000000000001138 141.0
TH2_k127_123681_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.327e-199 634.0
TH2_k127_123681_20 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000002585 92.0
TH2_k127_123681_23 Protein of unknown function (DUF1328) - - - 0.0000000000001071 73.0
TH2_k127_123681_25 phosphate ion binding K02040 - - 0.0003189 45.0
TH2_k127_123681_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 591.0
TH2_k127_123681_4 D-gluconate metabolic process K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 524.0
TH2_k127_123681_5 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 535.0
TH2_k127_123681_6 L-allo-threonine aldolase activity K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 468.0
TH2_k127_123681_7 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 442.0
TH2_k127_123681_8 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 432.0
TH2_k127_123681_9 protein-(glutamine-N5) methyltransferase activity K00543,K16130,K18896,K18897,K21515 - 2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 424.0
TH2_k127_1238144_1 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 325.0
TH2_k127_1243447_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 513.0
TH2_k127_1243447_1 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000002595 113.0
TH2_k127_1243447_2 PFAM Fibronectin, type III domain - - - 0.000000000000001288 90.0
TH2_k127_1250901_0 Alkyl sulfatase dimerisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 617.0
TH2_k127_1250901_1 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000003744 180.0
TH2_k127_1250901_2 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.0003059 46.0
TH2_k127_1253924_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 6.774e-220 704.0
TH2_k127_1253924_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 308.0
TH2_k127_1253924_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007709 255.0
TH2_k127_1253924_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000004978 175.0
TH2_k127_1253924_4 metallopeptidase activity K01993,K13408,K16922 - - 0.000000000000000000000000000001276 122.0
TH2_k127_1254492_0 TonB-dependent receptor - - - 0.0 1122.0
TH2_k127_1254492_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 3.517e-230 723.0
TH2_k127_1254492_2 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 614.0
TH2_k127_1254492_3 response to nickel cation K07722 GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016151,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032991,GO:0032993,GO:0042802,GO:0043167,GO:0043169,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071840,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000001668 217.0
TH2_k127_1265710_0 response regulator K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 496.0
TH2_k127_1265710_1 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.0000000000000000003676 87.0
TH2_k127_1265710_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000001568 54.0
TH2_k127_1269685_0 Histidine kinase K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 530.0
TH2_k127_1269685_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 478.0
TH2_k127_1269685_2 Two component signalling adaptor domain K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 455.0
TH2_k127_1269685_3 Chemotaxis protein methyltransferase K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000005325 226.0
TH2_k127_1269685_4 Chemotaxis phosphatase, CheZ K03414 - - 0.00000000000000000000000000000000000000000000000000000000000000257 224.0
TH2_k127_1269685_5 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000002233 213.0
TH2_k127_1272168_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 8.031e-226 704.0
TH2_k127_1272168_1 Dehydrogenase K00382 - 1.8.1.4 1.171e-197 620.0
TH2_k127_1276140_0 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 3.053e-228 714.0
TH2_k127_1276140_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 345.0
TH2_k127_1276140_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 310.0
TH2_k127_1276140_3 response regulator K03413 - - 0.000000000000000000000000003891 115.0
TH2_k127_1276140_4 FtsZ-dependent cytokinesis - - - 0.00000000000000000007141 89.0
TH2_k127_1282235_0 dead DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 1.017e-281 876.0
TH2_k127_1282235_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 6.661e-229 715.0
TH2_k127_1282235_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 610.0
TH2_k127_1282235_3 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 502.0
TH2_k127_1282235_4 ATPase activity K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 389.0
TH2_k127_1282235_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 383.0
TH2_k127_1282235_6 putrescine transport K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 359.0
TH2_k127_1282235_7 DNA import into cell involved in transformation K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 283.0
TH2_k127_1282235_8 dead DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000001627 179.0
TH2_k127_1286764_0 cobalamin synthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 426.0
TH2_k127_1286764_1 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 323.0
TH2_k127_1286764_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000003436 212.0
TH2_k127_1286764_3 PEP-CTERM motif - - - 0.0000000000000000000000000000000000007418 149.0
TH2_k127_1299290_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 6.865e-245 759.0
TH2_k127_1299290_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001163 274.0
TH2_k127_1299290_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005988 268.0
TH2_k127_1299290_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000231 136.0
TH2_k127_1302821_0 Transposase (IS116 IS110 IS902 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 336.0
TH2_k127_1302821_1 Ester cyclase - - - 0.000000000000000000000000000001104 127.0
TH2_k127_1306968_0 Outer membrane protein peptidoglycan-associated (Lipo)protein K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 448.0
TH2_k127_1306968_1 Bacterial Ig-like domain (group 2) - - - 0.0000000000000000000000000000000000000000000000000000000000001982 227.0
TH2_k127_1324517_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 478.0
TH2_k127_1324517_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 400.0
TH2_k127_1324517_2 ABC transporter - - - 0.0000000000000000000000000000000000000000000005671 173.0
TH2_k127_1324517_3 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000001055 76.0
TH2_k127_1355489_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 444.0
TH2_k127_1355489_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000001327 119.0
TH2_k127_1355489_3 toxin-antitoxin pair type II binding - - - 0.0000001886 55.0
TH2_k127_1357946_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 564.0
TH2_k127_1357946_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000001716 225.0
TH2_k127_1357946_2 peptidyl-tyrosine sulfation K02450 - - 0.00000000000000000000000000001591 126.0
TH2_k127_1357946_3 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.0000000000000000000000000000526 127.0
TH2_k127_1357946_4 phosphohistidine phosphatase, SixA K08296 - - 0.0005045 47.0
TH2_k127_1369826_0 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000003073 192.0
TH2_k127_1369826_1 glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000694 187.0
TH2_k127_1369826_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000001697 172.0
TH2_k127_1369826_3 Polysaccharide biosynthesis protein - - - 0.000000000000000002977 98.0
TH2_k127_1369826_4 COG0438 Glycosyltransferase - - - 0.00000004114 58.0
TH2_k127_1374955_0 Shikimate / quinate 5-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000005395 226.0
TH2_k127_1374955_1 Resolvase - - - 0.00000397 49.0
TH2_k127_1377897_0 General secretion pathway protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 349.0
TH2_k127_1377897_1 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000005543 183.0
TH2_k127_1377897_2 PFAM Type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000002741 164.0
TH2_k127_1377897_4 Prokaryotic N-terminal methylation motif K02457 - - 0.000002937 57.0
TH2_k127_1377897_5 Type II secretion system (T2SS), protein J K02459 - - 0.0003135 50.0
TH2_k127_1394243_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 388.0
TH2_k127_1394243_1 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 343.0
TH2_k127_1394243_10 - - - - 0.000000000000000000000000001658 116.0
TH2_k127_1394243_11 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000005311 56.0
TH2_k127_1394243_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001557 269.0
TH2_k127_1394243_4 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001289 269.0
TH2_k127_1394243_5 - - - - 0.000000000000000000000000000000000000000000000000000000000003306 211.0
TH2_k127_1394243_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000004426 194.0
TH2_k127_1394243_8 cellulase activity - - - 0.00000000000000000000000000000000001114 153.0
TH2_k127_1394243_9 1,4-alpha-glucan branching enzyme activity - - - 0.000000000000000000000000000000006238 132.0
TH2_k127_1401232_0 phosphorelay signal transduction system K10941 - - 1.042e-219 689.0
TH2_k127_1401232_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 432.0
TH2_k127_1401232_2 phosphorelay sensor kinase activity K07708,K07710,K10942 - 2.7.13.3 0.000000000000000000000000000000003308 134.0
TH2_k127_1401232_3 DNA integration - - - 0.0000000009392 61.0
TH2_k127_1407668_0 metalloendopeptidase activity K08602 - - 6.452e-283 881.0
TH2_k127_1407668_1 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001074 264.0
TH2_k127_1407668_2 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000004894 130.0
TH2_k127_1407668_5 2 iron, 2 sulfur cluster binding K02192 GO:0003674,GO:0005488,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.000000000000000001136 88.0
TH2_k127_1422641_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 8.874e-209 659.0
TH2_k127_1422641_1 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000001146 225.0
TH2_k127_1422641_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 0.00000000000000000000000769 104.0
TH2_k127_1441778_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 587.0
TH2_k127_1441778_1 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 390.0
TH2_k127_1441778_2 Evidence 2b Function of strongly homologous gene K01740,K03430,K05306,K09469 GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 345.0
TH2_k127_1441778_3 lysyltransferase activity K07027 - - 0.000000000000000000000000005243 118.0
TH2_k127_1487263_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 9.982e-227 720.0
TH2_k127_1487263_1 coenzyme binding K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 303.0
TH2_k127_1487263_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000007415 154.0
TH2_k127_1487263_5 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000001621 116.0
TH2_k127_1488380_0 Protein of unknown function (DUF1353) - - - 0.00000000000000000000000000000000000000000000000002715 185.0
TH2_k127_1529678_0 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.00000000000000000000000000000000000001735 157.0
TH2_k127_1532196_0 Glycosyl hydrolases family 8 K00694 - 2.4.1.12 0.0 1087.0
TH2_k127_1532196_1 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 510.0
TH2_k127_1532196_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 410.0
TH2_k127_1532196_3 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 315.0
TH2_k127_1532196_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000001202 228.0
TH2_k127_1532196_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000002638 192.0
TH2_k127_1537624_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 547.0
TH2_k127_1537624_1 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000001505 229.0
TH2_k127_1565451_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 513.0
TH2_k127_1565451_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 481.0
TH2_k127_1565451_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 392.0
TH2_k127_1565451_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 331.0
TH2_k127_1565451_4 Phosphoserine phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 289.0
TH2_k127_1565451_5 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000002014 193.0
TH2_k127_1565451_6 Flagellar Motor Protein K02557 - - 0.000000000000000000000000000000000000000009905 161.0
TH2_k127_1565451_7 MFS/sugar transport protein K06902 - - 0.000000000000000000000000000000000000000831 155.0
TH2_k127_1570455_0 PhoQ Sensor - - - 5.87e-233 745.0
TH2_k127_1570455_1 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 531.0
TH2_k127_157386_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000001352 216.0
TH2_k127_157386_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000004832 195.0
TH2_k127_157386_2 SnoaL-like domain - - - 0.000000000000000000000000000000000004536 141.0
TH2_k127_157386_3 haloacid dehalogenase-like hydrolase - - - 0.0000000001049 66.0
TH2_k127_160593_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 466.0
TH2_k127_160593_1 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003231 250.0
TH2_k127_160593_2 - - - - 0.00000000000000000003285 96.0
TH2_k127_1631722_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1314.0
TH2_k127_1631722_1 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.0 1109.0
TH2_k127_1631722_10 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 398.0
TH2_k127_1631722_11 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 375.0
TH2_k127_1631722_12 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 368.0
TH2_k127_1631722_13 Tetratricopeptide repeat K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 342.0
TH2_k127_1631722_14 Protein of unknown function DUF47 K02039,K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 331.0
TH2_k127_1631722_15 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 293.0
TH2_k127_1631722_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 292.0
TH2_k127_1631722_17 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008327 273.0
TH2_k127_1631722_18 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000002373 234.0
TH2_k127_1631722_19 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000004767 221.0
TH2_k127_1631722_2 ResB-like family K07399 - - 1.461e-254 792.0
TH2_k127_1631722_20 adenosylhomocysteine nucleosidase activity K01243,K03527 - 1.17.7.4,3.2.2.9 0.000000000000000000000000000000000000000000000002078 183.0
TH2_k127_1631722_3 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 579.0
TH2_k127_1631722_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 572.0
TH2_k127_1631722_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 521.0
TH2_k127_1631722_6 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 489.0
TH2_k127_1631722_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 422.0
TH2_k127_1631722_8 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 416.0
TH2_k127_1631722_9 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 421.0
TH2_k127_1636384_0 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000003099 194.0
TH2_k127_1636384_1 glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000004049 190.0
TH2_k127_1636384_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000007357 185.0
TH2_k127_1636384_3 Methionine biosynthesis protein MetW - - - 0.000000000000000000000003844 110.0
TH2_k127_1636384_4 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000172 104.0
TH2_k127_1636384_5 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.000000000004702 76.0
TH2_k127_1638832_0 DNA-templated transcription, termination K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 2.119e-228 711.0
TH2_k127_1638832_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 505.0
TH2_k127_1638832_2 dihydroorotate dehydrogenase activity K00226,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 353.0
TH2_k127_1638832_3 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000001021 269.0
TH2_k127_1638832_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000004188 89.0
TH2_k127_1638832_5 2 iron, 2 sulfur cluster binding K02823 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0042602,GO:0052875,GO:0055114 - 0.000000000001438 68.0
TH2_k127_1674035_0 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 564.0
TH2_k127_1674035_1 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 372.0
TH2_k127_1674035_2 COGs COG5616 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 306.0
TH2_k127_1674035_3 Transposase K07494 - - 0.0000000000000000000000000000000002954 134.0
TH2_k127_1686586_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004017 278.0
TH2_k127_1686586_1 - - - - 0.0000008862 55.0
TH2_k127_1686586_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0001416 44.0
TH2_k127_1721748_0 xylulokinase activity K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 391.0
TH2_k127_1721748_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000005077 254.0
TH2_k127_1721748_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000174 157.0
TH2_k127_1721748_3 - - - - 0.0000000000000000000000000000000007301 133.0
TH2_k127_1728504_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 1.15e-309 961.0
TH2_k127_1728504_1 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 327.0
TH2_k127_1728504_2 oxidoreductase DsbE K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001446 263.0
TH2_k127_1728504_3 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000000001749 176.0
TH2_k127_1728504_4 4fe-4S ferredoxin, iron-sulfur binding domain protein K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.00000000000000000000004705 104.0
TH2_k127_1728504_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000234 50.0
TH2_k127_173347_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 514.0
TH2_k127_173347_1 PFAM Peptidase C14, caspase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000001917 231.0
TH2_k127_173347_2 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000007945 195.0
TH2_k127_173347_3 - - - - 0.000000004642 64.0
TH2_k127_1744111_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1777.0
TH2_k127_1744111_1 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 469.0
TH2_k127_1744111_2 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 428.0
TH2_k127_1744111_3 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000002913 63.0
TH2_k127_1750957_0 cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 441.0
TH2_k127_1750957_1 Restriction endonuclease K07448 - - 0.00000000000000000000000000000000000000001892 154.0
TH2_k127_1750957_2 MltA-interacting MipA family protein K07274 - - 0.00000000000000000000000000000003436 132.0
TH2_k127_1750957_3 Restriction endonuclease K07448 - - 0.00000000000000000000000000009128 119.0
TH2_k127_1750957_4 TonB-dependent receptor K02014,K02456,K02457,K02458,K10926,K10930,K10931 GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0008150,GO:0009289,GO:0009405,GO:0009987,GO:0016043,GO:0030030,GO:0042995,GO:0044419,GO:0044464,GO:0051704,GO:0071840 - 0.000000000009641 70.0
TH2_k127_1750957_5 histone H2A-K13 ubiquitination K01338,K07157 - 3.4.21.53 0.00001817 49.0
TH2_k127_1785643_0 protein catabolic process K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 0.0 1013.0
TH2_k127_1785643_1 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 1.433e-276 859.0
TH2_k127_1785643_2 O-methyltransferase activity K13571,K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119,6.3.1.19 2.364e-239 747.0
TH2_k127_1785643_3 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 417.0
TH2_k127_1785643_4 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 336.0
TH2_k127_1785643_5 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000002575 207.0
TH2_k127_1785643_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000388 199.0
TH2_k127_178572_0 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000003438 264.0
TH2_k127_178572_2 Mo-molybdopterin cofactor metabolic process K03636 - - 0.000000000000000000000000000000002823 133.0
TH2_k127_179919_0 phosphorelay signal transduction system K07714 - - 4.746e-208 654.0
TH2_k127_179919_1 photoreceptor activity K14978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 477.0
TH2_k127_179919_2 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 300.0
TH2_k127_1799642_0 PFAM SufBD protein K07033,K09014,K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 430.0
TH2_k127_1799642_1 transporter K07238,K11021,K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 299.0
TH2_k127_1799642_2 PFAM ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000003816 223.0
TH2_k127_1799642_3 metallocarboxypeptidase activity - - - 0.0000000000000000000000000000000000000000000000002661 186.0
TH2_k127_1799642_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000109 126.0
TH2_k127_1799642_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000007812 94.0
TH2_k127_1799642_6 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000002807 57.0
TH2_k127_1807618_0 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000004904 246.0
TH2_k127_1807618_1 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000000007284 240.0
TH2_k127_1807618_2 aggregation factor core protein MAFp3, isoform C - - - 0.000000000000000000000000000000000000000000000006607 188.0
TH2_k127_188938_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 8.854e-296 914.0
TH2_k127_188938_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000001934 169.0
TH2_k127_1906052_0 - - - - 6.254e-255 801.0
TH2_k127_1906052_1 ATPase activity K02017,K02018,K03750,K15497 - 2.10.1.1,3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 495.0
TH2_k127_1906052_2 PBP superfamily domain K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 417.0
TH2_k127_1906052_3 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 377.0
TH2_k127_1906052_4 tungstate binding K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 333.0
TH2_k127_1906052_5 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004294 266.0
TH2_k127_1906052_6 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000433 261.0
TH2_k127_1926021_0 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 409.0
TH2_k127_1926021_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 405.0
TH2_k127_1937287_0 Tail protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 375.0
TH2_k127_1937287_1 Tail protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 348.0
TH2_k127_1943545_0 ATP synthase alpha/beta family, beta-barrel domain K02412 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 605.0
TH2_k127_1943545_1 phosphorelay signal transduction system K02411,K03223,K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001487 260.0
TH2_k127_1943545_2 PFAM MgtE intracellular K02383 - - 0.0000000000000000000000000000001425 134.0
TH2_k127_1943545_3 FliG middle domain K02410 - - 0.0000000000000000000006752 95.0
TH2_k127_1949129_0 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 347.0
TH2_k127_1949129_1 Calcium binding - - - 0.000000000000000000000000000000000000000000002727 166.0
TH2_k127_1949129_2 - - - - 0.00000000000000000000003152 100.0
TH2_k127_1949129_4 Methyltransferase - - - 0.00000002093 63.0
TH2_k127_1949129_5 - - - - 0.000002353 55.0
TH2_k127_1963652_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.27e-309 951.0
TH2_k127_1963652_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 9.999e-301 923.0
TH2_k127_1963652_11 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001092 230.0
TH2_k127_1963652_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000001917 220.0
TH2_k127_1963652_13 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000000000000006854 214.0
TH2_k127_1963652_14 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000443 196.0
TH2_k127_1963652_16 - K07275 - - 0.000000000000000000000000000006465 127.0
TH2_k127_1963652_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000001771 49.0
TH2_k127_1963652_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 540.0
TH2_k127_1963652_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 484.0
TH2_k127_1963652_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 462.0
TH2_k127_1963652_5 AAA domain, putative AbiEii toxin, Type IV TA system K09817,K09820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 424.0
TH2_k127_1963652_6 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 416.0
TH2_k127_1963652_7 pectinesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 399.0
TH2_k127_1963652_8 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 394.0
TH2_k127_1963652_9 Zinc-uptake complex component A periplasmic K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 343.0
TH2_k127_1984059_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 1.252e-249 774.0
TH2_k127_1984059_1 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 550.0
TH2_k127_2033860_0 Major facilitator Superfamily - - - 2.447e-194 613.0
TH2_k127_2033860_1 silver ion transport K15726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 498.0
TH2_k127_2033860_2 Uncharacterised BCR, YnfA/UPF0060 family K09771 - - 0.00000000000000000000000000000000000000000000002049 172.0
TH2_k127_2066714_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.013e-318 981.0
TH2_k127_2066714_1 glutamate dehydrogenase [NAD(P)+] activity K00261,K00262 - 1.4.1.3,1.4.1.4 1.934e-222 694.0
TH2_k127_2066714_10 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 435.0
TH2_k127_2066714_11 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 396.0
TH2_k127_2066714_12 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001517 282.0
TH2_k127_2066714_13 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005693 276.0
TH2_k127_2066714_16 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000000000000000000000000007572 173.0
TH2_k127_2066714_17 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.00000000000000000000000000000000000000000000004588 184.0
TH2_k127_2066714_18 COG2346, Truncated hemoglobins K06886 - - 0.00000000000000000000000000000000000000006712 159.0
TH2_k127_2066714_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 3.182e-210 662.0
TH2_k127_2066714_3 NeuB family K03856 - 2.5.1.54 1.693e-196 615.0
TH2_k127_2066714_4 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 606.0
TH2_k127_2066714_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 578.0
TH2_k127_2066714_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 535.0
TH2_k127_2066714_7 Proto-chlorophyllide reductase 57 kD subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 520.0
TH2_k127_2066714_8 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 459.0
TH2_k127_2066714_9 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 449.0
TH2_k127_209972_0 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 462.0
TH2_k127_209972_1 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 421.0
TH2_k127_209972_2 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 361.0
TH2_k127_209972_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002827 283.0
TH2_k127_209972_4 Met-10+ like-protein - - - 0.0000000000000000000000000000000000000000000000000619 183.0
TH2_k127_209972_5 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000000000000000000000001436 157.0
TH2_k127_209972_6 Domain of unknown function (DUF4160) - - - 0.000000000000000000000000000000000204 133.0
TH2_k127_209972_7 Protein of unknown function (DUF2442) - - - 0.0000000000000001676 85.0
TH2_k127_209972_8 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000926 63.0
TH2_k127_2149924_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.372e-234 733.0
TH2_k127_2149924_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 598.0
TH2_k127_2149924_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 331.0
TH2_k127_2149924_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000234 286.0
TH2_k127_2149924_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.00000000000000000000000000000000000002007 151.0
TH2_k127_2149924_5 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000003547 125.0
TH2_k127_2149924_6 ATP synthase delta (OSCP) subunit K02113 - - 0.000000000000000001017 93.0
TH2_k127_2149924_7 PFAM H transporting two-sector ATPase C subunit K02110 - - 0.00000000000006836 74.0
TH2_k127_2243578_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 9.665e-242 750.0
TH2_k127_2243578_1 Histidine kinase K00060,K07777 - 1.1.1.103,2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 574.0
TH2_k127_2243578_3 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000494 235.0
TH2_k127_2243578_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000001727 229.0
TH2_k127_2243578_5 response regulator, receiver K02479 - - 0.0000000000000000000000000000000000000000000000000000000009783 208.0
TH2_k127_2254299_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 3.691e-295 917.0
TH2_k127_2254299_1 tungstate binding K02020 - - 0.000000000000000000000000000000000000000000000001127 185.0
TH2_k127_233957_0 Protein of unknown function (DUF3604) - - - 0.0 1030.0
TH2_k127_233957_1 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001487 265.0
TH2_k127_233957_2 HupE / UreJ protein - - - 0.00000002972 57.0
TH2_k127_2343520_0 cation transport ATPase K17686 - 3.6.3.54 5.4e-323 1002.0
TH2_k127_2343520_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001018 241.0
TH2_k127_2343520_2 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000000000000000000007755 166.0
TH2_k127_2343520_3 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000002744 102.0
TH2_k127_2343520_4 Cytochrome c554 and c-prime - - - 0.0000001944 62.0
TH2_k127_2355507_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 593.0
TH2_k127_2355507_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 496.0
TH2_k127_2355507_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 402.0
TH2_k127_2355507_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 374.0
TH2_k127_2355507_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006032 275.0
TH2_k127_2355507_5 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000001489 177.0
TH2_k127_2360903_0 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 379.0
TH2_k127_2360903_1 Transposase, Mutator family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 308.0
TH2_k127_2360903_2 chelatase, subunit chli K07391 - - 0.00000000000000000000000000000000000000000000000000002564 190.0
TH2_k127_2360903_3 Transposase - - - 0.000000000000000000000000000008331 121.0
TH2_k127_2360903_4 sequence-specific DNA binding K18830 - - 0.00000000000003517 76.0
TH2_k127_2360903_5 metallopeptidase activity K01179 - 3.2.1.4 0.000000000002591 81.0
TH2_k127_2360903_6 Protein of unknown function (DUF1501) - - - 0.000000000003189 79.0
TH2_k127_2365146_0 phosphorelay sensor kinase activity K02668 - 2.7.13.3 2.284e-256 802.0
TH2_k127_2365146_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 527.0
TH2_k127_2365146_2 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 528.0
TH2_k127_2365146_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 338.0
TH2_k127_2365146_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000476 216.0
TH2_k127_2365146_5 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000009562 196.0
TH2_k127_2366293_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 3.51e-196 614.0
TH2_k127_2366293_2 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000003117 168.0
TH2_k127_237657_0 MacB-like periplasmic core domain K02004 - - 6.257e-266 844.0
TH2_k127_237657_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 8.647e-252 782.0
TH2_k127_237657_10 photosystem II stabilization K02237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004457 253.0
TH2_k127_237657_11 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003492 245.0
TH2_k127_237657_12 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000000001908 233.0
TH2_k127_237657_13 crossover junction endodeoxyribonuclease activity K01160 - 3.1.22.4 0.00000000000000000000000000000000000000000000002628 177.0
TH2_k127_237657_14 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000000000246 140.0
TH2_k127_237657_15 response regulator - - - 0.000000000000000000000001206 106.0
TH2_k127_237657_16 Excisionase - - - 0.00000000007374 64.0
TH2_k127_237657_2 MacB-like periplasmic core domain K02004 - - 2.683e-195 616.0
TH2_k127_237657_3 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 497.0
TH2_k127_237657_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 487.0
TH2_k127_237657_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 387.0
TH2_k127_237657_6 Evidence 2b Function of strongly homologous gene K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 366.0
TH2_k127_237657_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 372.0
TH2_k127_237657_8 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 312.0
TH2_k127_237657_9 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 298.0
TH2_k127_2389200_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.396e-268 844.0
TH2_k127_2389200_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 438.0
TH2_k127_2389200_3 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000003174 118.0
TH2_k127_2400011_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 2e-211 663.0
TH2_k127_2400011_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 578.0
TH2_k127_2400011_2 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 532.0
TH2_k127_2400411_0 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000001767 223.0
TH2_k127_2400411_1 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000005937 196.0
TH2_k127_2400411_2 Psort location Cytoplasmic, score K09144 - - 0.000000000000000000000000000000000000000000000000006658 186.0
TH2_k127_2400411_3 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000005363 135.0
TH2_k127_2400411_4 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000001268 134.0
TH2_k127_2400411_5 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 0.000000000000000000006892 99.0
TH2_k127_2405267_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000009488 158.0
TH2_k127_2405267_1 Methyltransferase domain - - - 0.000000000000000000000000000000001597 134.0
TH2_k127_2405267_2 PFAM inositol monophosphatase K01082 - 3.1.3.7 0.000000000000000000000000000007878 134.0
TH2_k127_2405267_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000001698 98.0
TH2_k127_2407858_0 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 481.0
TH2_k127_2407858_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 430.0
TH2_k127_2407858_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 307.0
TH2_k127_2407858_3 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000002823 226.0
TH2_k127_2407858_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000001383 158.0
TH2_k127_2424176_0 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0 1054.0
TH2_k127_2424176_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0 1017.0
TH2_k127_2424176_2 Cytochrome b/b6/petB K00412 - - 2.003e-228 710.0
TH2_k127_2424176_3 oxidoreductase activity, acting on diphenols and related substances as donors K00240,K03886 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 517.0
TH2_k127_2424176_4 Cytochrome c K17052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 380.0
TH2_k127_2424176_6 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009228 278.0
TH2_k127_2424176_8 Domain of unknown function (DUF3463) - - - 0.000000000000000000000000000000000000000000000000000000001179 200.0
TH2_k127_2424176_9 - - - - 0.000000000000000000000000000000000000000001421 160.0
TH2_k127_2434506_0 PLD-like domain - - - 0.000000000000000000000000000843 122.0
TH2_k127_2434506_1 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.00000002594 66.0
TH2_k127_2434506_2 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - 0.0000001623 53.0
TH2_k127_2437648_0 Elongation factor G C-terminus K06207 - - 0.0 1035.0
TH2_k127_2437648_1 Glycosyl transferase family group 2 - - - 4.786e-194 615.0
TH2_k127_2437648_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 558.0
TH2_k127_2437648_3 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 297.0
TH2_k127_2437648_5 cell redox homeostasis K03671,K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000001348 199.0
TH2_k127_24405_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 502.0
TH2_k127_24405_1 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 420.0
TH2_k127_24405_2 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 409.0
TH2_k127_24405_3 Protein of unknown function (DUF3015) - - - 0.0000000000000000000000000000000000000000000000000000000009616 207.0
TH2_k127_24405_5 Domain of unknown function (DUF3332) - - - 0.0000000000000001787 87.0
TH2_k127_2441536_0 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 375.0
TH2_k127_2441536_1 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 349.0
TH2_k127_2441536_2 C-terminal of Roc, COR, domain - - - 0.00000000000000000000000000000000002039 139.0
TH2_k127_2459559_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 350.0
TH2_k127_2459559_1 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 329.0
TH2_k127_2459559_2 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002054 243.0
TH2_k127_2459559_3 Ubiquinol--cytochrome c reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004512 235.0
TH2_k127_2459559_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000001674 193.0
TH2_k127_2459559_6 Zn peptidase - - - 0.0000000000000000000000000000000000000002483 152.0
TH2_k127_2468972_0 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000008161 78.0
TH2_k127_2477178_0 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 375.0
TH2_k127_2477178_1 glycerophosphoryl diester phosphodiesterase K01113,K01126 - 3.1.3.1,3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005676 291.0
TH2_k127_2477178_3 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000003355 249.0
TH2_k127_2477178_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003588 227.0
TH2_k127_2479434_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.101e-202 640.0
TH2_k127_2479434_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 299.0
TH2_k127_2479434_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00406,K12263 - - 0.0000000000000000000000000000000000000000001092 164.0
TH2_k127_2479434_5 AntiSigma factor - - - 0.00000000000000000000000001103 112.0
TH2_k127_2489914_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 3.47e-279 863.0
TH2_k127_2489914_1 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 356.0
TH2_k127_2497326_0 Periplasmic binding protein - - - 2.717e-238 753.0
TH2_k127_2497326_1 WD40-like Beta Propeller Repeat K03641 - - 7.264e-234 728.0
TH2_k127_2497326_10 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 307.0
TH2_k127_2497326_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001112 271.0
TH2_k127_2497326_12 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001332 274.0
TH2_k127_2497326_13 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007352 269.0
TH2_k127_2497326_14 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000000000000000000000000000000004012 231.0
TH2_k127_2497326_15 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000003165 216.0
TH2_k127_2497326_16 energy transducer activity K03646,K03832 - - 0.000000000000000000000000000000000000000000000000000000000006446 220.0
TH2_k127_2497326_17 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000003532 196.0
TH2_k127_2497326_18 - - - - 0.0004827 44.0
TH2_k127_2497326_19 - - - - 0.0008741 42.0
TH2_k127_2497326_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.949e-215 685.0
TH2_k127_2497326_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 561.0
TH2_k127_2497326_4 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 552.0
TH2_k127_2497326_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 448.0
TH2_k127_2497326_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 388.0
TH2_k127_2497326_7 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 360.0
TH2_k127_2497326_8 Transposase K01991,K02557,K07161,K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 327.0
TH2_k127_2497326_9 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 317.0
TH2_k127_2522129_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 339.0
TH2_k127_2522129_1 cellulase activity - - - 0.00001335 55.0
TH2_k127_2523914_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 528.0
TH2_k127_2523914_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 519.0
TH2_k127_2523914_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000004758 227.0
TH2_k127_2523914_11 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000002351 207.0
TH2_k127_2523914_12 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000007192 193.0
TH2_k127_2523914_13 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000009975 181.0
TH2_k127_2523914_14 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000001266 166.0
TH2_k127_2523914_15 Sulfurtransferase TusA - - - 0.000000000000000000000000006705 113.0
TH2_k127_2523914_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 421.0
TH2_k127_2523914_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 406.0
TH2_k127_2523914_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 349.0
TH2_k127_2523914_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 303.0
TH2_k127_2523914_7 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004209 263.0
TH2_k127_2523914_8 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003761 235.0
TH2_k127_2523914_9 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000002559 237.0
TH2_k127_2556883_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 426.0
TH2_k127_2556883_1 phage integrase domain protein SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 335.0
TH2_k127_2556883_2 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 324.0
TH2_k127_2556883_3 - K07484 - - 0.0000000000000001743 79.0
TH2_k127_2556883_4 Belongs to the 'phage' integrase family K04763 - - 0.00003657 46.0
TH2_k127_2566628_0 Putative transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 419.0
TH2_k127_2566628_1 Fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 370.0
TH2_k127_2566628_2 phage integrase domain protein SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 322.0
TH2_k127_2566628_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000002869 209.0
TH2_k127_2566628_4 Rhodanese Homology Domain - - - 0.000000000000001497 77.0
TH2_k127_2566628_5 serine threonine protein kinase K12132 - 2.7.11.1 0.0001107 49.0
TH2_k127_2577596_0 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 299.0
TH2_k127_2577596_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000007562 228.0
TH2_k127_2577596_2 transposition K07497 - - 0.0000000000000000000000000000003936 122.0
TH2_k127_2577596_3 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000001165 130.0
TH2_k127_2577596_4 transposition K07497 - - 0.000000000000000000007456 91.0
TH2_k127_2577596_5 transposition K07497 - - 0.000000004258 59.0
TH2_k127_2577596_6 Helix-turn-helix K21498 - - 0.0002964 44.0
TH2_k127_2583378_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 550.0
TH2_k127_2583378_1 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 366.0
TH2_k127_2676852_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 5.101e-204 649.0
TH2_k127_2676852_1 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 464.0
TH2_k127_2676852_10 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001245 244.0
TH2_k127_2676852_11 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000105 232.0
TH2_k127_2676852_12 Protein of unknown function (DUF3485) - - - 0.00000000000000000000000000000000000000000000000000006131 195.0
TH2_k127_2676852_13 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000008029 171.0
TH2_k127_2676852_14 Plasmid partitioning protein ParA K03496 - - 0.0000000000000000000000000015 122.0
TH2_k127_2676852_15 - - - - 0.000000000000000000009196 107.0
TH2_k127_2676852_16 Flagellar hook-associated protein 2 N-terminus - - - 0.00000000000000000407 98.0
TH2_k127_2676852_17 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00000000000000006773 87.0
TH2_k127_2676852_18 Esterase PHB depolymerase - - - 0.000000000001605 81.0
TH2_k127_2676852_19 Global regulator protein family K03563 - - 0.0000000003883 64.0
TH2_k127_2676852_2 GHMP kinase domain protein K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 457.0
TH2_k127_2676852_20 domain, Protein - - - 0.00000006439 56.0
TH2_k127_2676852_21 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00002983 58.0
TH2_k127_2676852_22 cytosine-specific methyltransferase K00558 - 2.1.1.37 0.0002028 49.0
TH2_k127_2676852_23 PFAM TPR repeat-containing protein - - - 0.0005638 48.0
TH2_k127_2676852_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 367.0
TH2_k127_2676852_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 346.0
TH2_k127_2676852_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 354.0
TH2_k127_2676852_6 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 308.0
TH2_k127_2676852_7 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 302.0
TH2_k127_2676852_8 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 300.0
TH2_k127_2676852_9 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001613 289.0
TH2_k127_267916_0 Site-specific recombinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 463.0
TH2_k127_267916_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 338.0
TH2_k127_267916_2 Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000000000000000000000001417 158.0
TH2_k127_267916_3 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000000001481 125.0
TH2_k127_267916_4 Helix-turn-helix domain - - - 0.00000000000000000000000002036 113.0
TH2_k127_267916_5 addiction module antidote protein HigA K21498 - - 0.00000000000000000000007767 100.0
TH2_k127_267916_7 methyltransferase - - - 0.000000000011 67.0
TH2_k127_2686095_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 595.0
TH2_k127_2686095_1 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000000000000000000000000000001415 207.0
TH2_k127_2686095_2 Transposase K07491 - - 0.0004631 45.0
TH2_k127_2703526_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000000002863 62.0
TH2_k127_2703526_2 Endonuclease I - - - 0.00002025 51.0
TH2_k127_2706936_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1138.0
TH2_k127_2706936_1 Evidence 5 No homology to any previously reported sequences K07126 - - 0.0000000000000001033 83.0
TH2_k127_2713259_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 7.492e-266 820.0
TH2_k127_2713259_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.263e-242 764.0
TH2_k127_2713259_10 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 359.0
TH2_k127_2713259_11 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 329.0
TH2_k127_2713259_12 RNA-DNA hybrid ribonuclease activity K03471 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 328.0
TH2_k127_2713259_13 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 324.0
TH2_k127_2713259_14 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 307.0
TH2_k127_2713259_15 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 306.0
TH2_k127_2713259_16 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000004563 270.0
TH2_k127_2713259_18 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000000007955 182.0
TH2_k127_2713259_19 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000000000000000002246 181.0
TH2_k127_2713259_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 7.204e-240 744.0
TH2_k127_2713259_20 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000000002904 143.0
TH2_k127_2713259_22 BolA family transcriptional regulator K09780 - - 0.000000000000000001956 87.0
TH2_k127_2713259_24 peptidyl-tyrosine sulfation - - - 0.0008197 51.0
TH2_k127_2713259_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 1.728e-218 687.0
TH2_k127_2713259_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.23e-202 637.0
TH2_k127_2713259_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 588.0
TH2_k127_2713259_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 502.0
TH2_k127_2713259_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 456.0
TH2_k127_2713259_8 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 398.0
TH2_k127_2713259_9 metalloendopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 400.0
TH2_k127_2713282_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000001032 194.0
TH2_k127_2722205_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1422.0
TH2_k127_2722205_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000176 225.0
TH2_k127_2722205_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000003764 189.0
TH2_k127_2722205_3 regulation of DNA repair K03565,K19002 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 0.00000000000000000001181 95.0
TH2_k127_2730343_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.498e-263 818.0
TH2_k127_2730343_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 361.0
TH2_k127_2730343_2 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000004458 207.0
TH2_k127_2740688_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1472.0
TH2_k127_2740688_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1037.0
TH2_k127_2740688_10 Ion channel - - - 0.00000000000000000000000000000000000001016 154.0
TH2_k127_2740688_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 6.646e-195 614.0
TH2_k127_2740688_3 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 563.0
TH2_k127_2740688_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 528.0
TH2_k127_2740688_5 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 447.0
TH2_k127_2740688_6 Evidence 2b Function of strongly homologous gene K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 447.0
TH2_k127_2740688_7 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 402.0
TH2_k127_2740688_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 359.0
TH2_k127_2740688_9 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000001531 200.0
TH2_k127_2749936_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 1324.0
TH2_k127_2749936_1 Histidine kinase - - - 2.398e-303 940.0
TH2_k127_2749936_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 391.0
TH2_k127_2749936_3 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 364.0
TH2_k127_2749936_4 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 342.0
TH2_k127_2769400_0 belongs to the aldehyde dehydrogenase family K00294,K13821 - 1.2.1.88,1.5.5.2 0.0 1080.0
TH2_k127_2772794_0 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 378.0
TH2_k127_2772794_1 B-1 B cell differentiation - - - 0.0000000000001731 74.0
TH2_k127_2772794_2 Protein of unknown function (DUF1003) - - - 0.0000000002948 64.0
TH2_k127_2772794_3 - - - - 0.00008529 48.0
TH2_k127_2790647_0 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000159 230.0
TH2_k127_2790647_1 - - - - 0.000000000000000000000000000003964 129.0
TH2_k127_2820076_0 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 418.0
TH2_k127_2820076_1 spermidine synthase activity K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 411.0
TH2_k127_2820076_2 branched-chain-amino-acid transaminase activity K00824 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 345.0
TH2_k127_2820076_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001096 249.0
TH2_k127_2820076_5 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000000000000000000000003513 220.0
TH2_k127_2820076_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000002194 186.0
TH2_k127_2820076_7 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000001003 176.0
TH2_k127_283626_0 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000366 264.0
TH2_k127_283626_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000002725 155.0
TH2_k127_283626_2 Copper binding proteins, plastocyanin/azurin family - - - 0.00004626 46.0
TH2_k127_2838008_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1673.0
TH2_k127_2838008_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 298.0
TH2_k127_2838008_2 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004975 218.0
TH2_k127_2842296_0 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00392 - 1.7.1.15,1.8.7.1 0.0 1315.0
TH2_k127_2842296_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1054.0
TH2_k127_2842296_10 Translation initiation factor IF-3, C-terminal domain K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 302.0
TH2_k127_2842296_11 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002407 262.0
TH2_k127_2842296_12 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000002048 241.0
TH2_k127_2842296_13 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002784 198.0
TH2_k127_2842296_14 2 iron, 2 sulfur cluster binding K04487,K13643 - 2.8.1.7 0.00000000000000000000000000000000000000000001382 166.0
TH2_k127_2842296_15 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000000009362 152.0
TH2_k127_2842296_16 sequence-specific DNA binding K03557,K07712 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000001175 157.0
TH2_k127_2842296_18 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000003107 74.0
TH2_k127_2842296_2 sulfate adenylyltransferase (ATP) activity K00860,K00955,K00956 - 2.7.1.25,2.7.7.4 3.01e-315 974.0
TH2_k127_2842296_3 protein tyrosine kinase activity K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 552.0
TH2_k127_2842296_4 sulfate reduction K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 503.0
TH2_k127_2842296_5 Glycosyl transferase family, a/b domain K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 464.0
TH2_k127_2842296_6 Proto-chlorophyllide reductase 57 kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 419.0
TH2_k127_2842296_7 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 415.0
TH2_k127_2842296_8 sulfate reduction K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 366.0
TH2_k127_2842296_9 B3/4 domain K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 306.0
TH2_k127_2842510_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 1.619e-273 842.0
TH2_k127_2842510_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 487.0
TH2_k127_2842510_2 photosynthesis - - - 0.0000000000000000000000000000000000000006625 149.0
TH2_k127_2856644_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 318.0
TH2_k127_2856644_1 NB-ARC domain - - - 0.0000000000000000000000000000000002867 151.0
TH2_k127_2860476_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 440.0
TH2_k127_2860476_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 341.0
TH2_k127_2860476_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 299.0
TH2_k127_2860476_3 GPR1 FUN34 yaaH family protein K07034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004602 267.0
TH2_k127_2860476_5 - - - - 0.000000000000000000000000000000000000000000000000000083 196.0
TH2_k127_2860476_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000001658 157.0
TH2_k127_28950_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 387.0
TH2_k127_28950_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003035 275.0
TH2_k127_28950_2 PFAM Glycosyl transferase family 4 K13007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006162 279.0
TH2_k127_28950_3 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000005558 219.0
TH2_k127_28950_4 PFAM Glycosyl transferase, family 25 K07270 - - 0.0000000000000000000000000000000000000000000002652 173.0
TH2_k127_29207_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 448.0
TH2_k127_29207_1 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 423.0
TH2_k127_29207_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 425.0
TH2_k127_29207_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000002099 256.0
TH2_k127_29207_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.000000000000000000000000000000000000000000000000000005176 195.0
TH2_k127_29207_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000001537 149.0
TH2_k127_2931448_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.477e-242 755.0
TH2_k127_2931448_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 341.0
TH2_k127_2931448_2 cell cycle K05589 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.000000000000000000000000000002059 123.0
TH2_k127_2931448_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000157 112.0
TH2_k127_2937019_0 PFAM AAA ATPase central domain protein - - - 1.3e-232 739.0
TH2_k127_2937019_1 Phage tail sheath C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 586.0
TH2_k127_2937019_2 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 456.0
TH2_k127_2937019_3 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 364.0
TH2_k127_2937019_4 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 329.0
TH2_k127_2937019_5 PFAM T4 bacteriophage base plate protein - - - 0.000000000000000000000000000000000000000000000000000000000003802 216.0
TH2_k127_2937019_6 cell septum assembly - - - 0.0000000000000000000000000000000003348 152.0
TH2_k127_2937019_7 - - - - 0.000000000000000000005229 109.0
TH2_k127_2937019_9 - - - - 0.0000000000001637 75.0
TH2_k127_295137_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 1.533e-238 755.0
TH2_k127_295137_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 455.0
TH2_k127_295137_2 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 413.0
TH2_k127_295137_3 Thiol disulfide Interchange Protein K03673 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003508 275.0
TH2_k127_295137_4 Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000001647 186.0
TH2_k127_2975860_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000605 280.0
TH2_k127_2976126_0 Cellulose synthase catalytic subunit (UDP-forming) K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 398.0
TH2_k127_2976126_1 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000006236 220.0
TH2_k127_2989880_0 Cro/C1-type HTH DNA-binding domain K07729 - - 0.00005964 49.0
TH2_k127_2989880_1 - - - - 0.0003659 52.0
TH2_k127_2989880_2 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563,K13626 - - 0.0007364 48.0
TH2_k127_2996672_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 1.562e-315 979.0
TH2_k127_2996672_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 1.128e-221 689.0
TH2_k127_2996672_2 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 488.0
TH2_k127_2996672_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000004831 188.0
TH2_k127_305791_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 394.0
TH2_k127_305791_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 356.0
TH2_k127_305791_2 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 310.0
TH2_k127_305791_3 ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 305.0
TH2_k127_305791_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000818 295.0
TH2_k127_305791_5 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 290.0
TH2_k127_305791_6 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000002409 225.0
TH2_k127_305791_7 O-Antigen ligase - - - 0.0000000000000000000000000000000001716 146.0
TH2_k127_30602_0 Pup-ligase protein K13571 - 6.3.1.19 6.655e-248 772.0
TH2_k127_30602_1 poly(3-hydroxybutyrate) depolymerase activity K07019 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 466.0
TH2_k127_30602_2 serine threonine protein kinase - - - 0.000000000000000000005206 99.0
TH2_k127_3068429_0 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000658 81.0
TH2_k127_3101935_0 COG3039 Transposase and inactivated derivatives, IS5 family K07481 - - 0.000000000000000000000000000000000000000000000000000000005827 216.0
TH2_k127_3101935_2 peptidase - - - 0.00002441 53.0
TH2_k127_3115665_0 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000001576 197.0
TH2_k127_3115665_1 iron dependent repressor - - - 0.00000000000000000000000000000000000000001093 175.0
TH2_k127_3115665_2 S23 ribosomal protein - - - 0.00000000000000000000000000000000000000003737 155.0
TH2_k127_3128096_0 silver ion transport K15726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 511.0
TH2_k127_3128096_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 421.0
TH2_k127_3128096_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 389.0
TH2_k127_3144785_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 469.0
TH2_k127_3144785_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000003297 161.0
TH2_k127_3195226_0 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 411.0
TH2_k127_3199572_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 379.0
TH2_k127_3199572_1 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000002199 179.0
TH2_k127_3199572_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000001113 167.0
TH2_k127_3199572_3 Transposase K07494 - - 0.00000000000000000000000000000007501 126.0
TH2_k127_3199745_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 358.0
TH2_k127_3199745_1 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000005773 225.0
TH2_k127_3199745_2 Peptidase family M28 K05994 - 3.4.11.10 0.000000000000000000000000000000000000000008143 170.0
TH2_k127_3199745_3 Pkd domain containing protein - - - 0.00000000000000000000000000000000000002926 163.0
TH2_k127_3199745_4 peptidase activity, acting on L-amino acid peptides K20276,K21449 - - 0.00000000000000000000009098 113.0
TH2_k127_3199745_5 metallopeptidase activity - - - 0.0000000000000000000006314 109.0
TH2_k127_3199745_6 PFAM FecR protein K20276 - - 0.0000000000000000000008608 106.0
TH2_k127_3199745_7 Helix-turn-helix domain - - - 0.00000000000000003935 82.0
TH2_k127_3199745_8 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.000000009988 59.0
TH2_k127_321027_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 8.966e-252 796.0
TH2_k127_321027_1 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 409.0
TH2_k127_321027_2 Flavodoxin-like fold K00355,K11748 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000005556 255.0
TH2_k127_3228422_0 Sigma-54 interaction domain K07714 - - 4.311e-250 777.0
TH2_k127_3228422_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 347.0
TH2_k127_3228422_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 321.0
TH2_k127_3228422_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000009739 168.0
TH2_k127_3228422_4 HDOD domain - - - 0.00000009362 55.0
TH2_k127_3317006_0 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000001436 198.0
TH2_k127_3317006_1 GYD domain - - - 0.0000000000000000000000000000000000003711 143.0
TH2_k127_3329013_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 299.0
TH2_k127_3329013_1 - - - - 0.00000000000000000000000000000000000000000000000007128 197.0
TH2_k127_3329013_2 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000000000000000000000007427 173.0
TH2_k127_3329013_3 Nucleotidyl transferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000002896 155.0
TH2_k127_3329013_4 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000004394 134.0
TH2_k127_3329013_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000145 128.0
TH2_k127_3350856_0 Protein of unknown function (DUF2384) - - - 0.000000000000000000000000000000000001113 143.0
TH2_k127_3350856_1 RES - - - 0.00000000000000000000000000000199 129.0
TH2_k127_3353959_0 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 316.0
TH2_k127_3353959_1 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 306.0
TH2_k127_3361696_0 Nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 329.0
TH2_k127_3368029_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 284.0
TH2_k127_3368029_1 pteridine-dependent deoxygenase K18240 - 4.1.3.40,4.1.3.45 0.00000000000000000000000000000000000000000000000000000000000002681 230.0
TH2_k127_3368029_2 xylanase chitin deacetylase K22278 - 3.5.1.104 0.0000000000000001795 86.0
TH2_k127_3373158_0 dead DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 395.0
TH2_k127_3373158_1 Outer membrane protease K01355,K08477,K08566,K13520 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009279,GO:0016020,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031975,GO:0043170,GO:0044238,GO:0044425,GO:0044462,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.23.48,3.4.23.49 0.000000000000000000000000000000000000000000000000000000000000004673 230.0
TH2_k127_337449_0 Glycosyltransferase 36 associated - - - 7.279e-314 986.0
TH2_k127_337449_1 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 540.0
TH2_k127_337449_10 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000001454 72.0
TH2_k127_337449_11 Beta/Gamma crystallin - - - 0.0000000006118 65.0
TH2_k127_337449_12 YtxH-like protein - - - 0.000001045 55.0
TH2_k127_337449_2 Protein of unknown function (DUF1207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001978 280.0
TH2_k127_337449_3 - - - - 0.000000000000000000000000000000000000000000000000000000002697 210.0
TH2_k127_337449_4 CDP-archaeol synthase K19664 - 2.7.7.67 0.00000000000000000000000000137 121.0
TH2_k127_337449_5 - - - - 0.0000000000000000000001457 100.0
TH2_k127_337449_7 Periplasmic or secreted lipoprotein K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.0000000000000000008608 94.0
TH2_k127_337449_8 CsbD-like - - - 0.00000000000000001564 85.0
TH2_k127_337449_9 Protein of unknown function (DUF3309) - - - 0.00000000000000006554 82.0
TH2_k127_3422251_0 radical SAM domain protein - - - 0.0 1065.0
TH2_k127_3422251_1 NHL repeat - - - 3.829e-244 757.0
TH2_k127_3422251_10 hydrogen-translocating pyrophosphatase activity K15987 - 3.6.1.1 0.0000000000000000000000000009839 112.0
TH2_k127_3422251_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000000001257 115.0
TH2_k127_3422251_2 denitrification pathway - - - 3.003e-231 720.0
TH2_k127_3422251_3 denitrification pathway - - - 1.3e-213 670.0
TH2_k127_3422251_4 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 471.0
TH2_k127_3422251_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 452.0
TH2_k127_3422251_9 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000004325 115.0
TH2_k127_3445529_0 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 292.0
TH2_k127_3445529_1 Pfam:KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 291.0
TH2_k127_3445529_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001252 280.0
TH2_k127_3445529_3 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000004877 192.0
TH2_k127_3473469_0 cell redox homeostasis K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000829 177.0
TH2_k127_3473469_1 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000000000002749 123.0
TH2_k127_3473469_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000009344 50.0
TH2_k127_3473469_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.000005754 49.0
TH2_k127_3483163_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1497.0
TH2_k127_3483163_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 6.306e-253 784.0
TH2_k127_3483163_10 'glutamate synthase K00528,K03388 - 1.18.1.2,1.19.1.1,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000383 275.0
TH2_k127_3483163_11 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000476 279.0
TH2_k127_3483163_12 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001966 258.0
TH2_k127_3483163_13 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000112 241.0
TH2_k127_3483163_14 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000000001325 220.0
TH2_k127_3483163_15 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000001111 211.0
TH2_k127_3483163_16 IMP dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000009969 194.0
TH2_k127_3483163_17 belongs to the thioredoxin family K14949,K20543 - 2.7.11.1 0.00000000000000000000000000000000000000000000000007841 189.0
TH2_k127_3483163_18 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K00652,K01935 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47,6.3.3.3 0.0000000000000000000000000000000000000001252 160.0
TH2_k127_3483163_19 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0003512 47.0
TH2_k127_3483163_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 8.619e-205 651.0
TH2_k127_3483163_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 500.0
TH2_k127_3483163_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 493.0
TH2_k127_3483163_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 428.0
TH2_k127_3483163_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 374.0
TH2_k127_3483163_7 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 355.0
TH2_k127_3483163_8 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 302.0
TH2_k127_3483163_9 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 284.0
TH2_k127_3491296_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 1.61e-203 643.0
TH2_k127_3491296_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 364.0
TH2_k127_3491296_2 tRNA processing K06864,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 358.0
TH2_k127_3491296_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001415 247.0
TH2_k127_3562157_0 FAD binding domain K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 362.0
TH2_k127_3562157_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 302.0
TH2_k127_3562157_2 Domain of unknown function (DUF4124) K08309 - - 0.000000000000000000000000000000000000000000006573 171.0
TH2_k127_3563008_0 Cellulose synthase catalytic subunit (UDP-forming) K00694 - 2.4.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 381.0
TH2_k127_3563008_1 MEKHLA domain - - - 0.000000000000000000000000000008781 119.0
TH2_k127_3563008_2 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000001962 104.0
TH2_k127_3563862_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 301.0
TH2_k127_3563862_1 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000001555 216.0
TH2_k127_3567900_0 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004727 249.0
TH2_k127_3567900_1 GNAT acetyltransferase - - - 0.000000000000000000000000000000002928 141.0
TH2_k127_3567900_2 response to heat - - - 0.000000000000000000004375 103.0
TH2_k127_3579421_0 alpha amylase, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 318.0
TH2_k127_3579421_1 General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases K08276 GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005575,GO:0005623,GO:0008150,GO:0009892,GO:0010466,GO:0010605,GO:0010951,GO:0019222,GO:0030162,GO:0030234,GO:0030288,GO:0030313,GO:0030414,GO:0031323,GO:0031324,GO:0031975,GO:0032268,GO:0032269,GO:0042597,GO:0043086,GO:0044092,GO:0044464,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0080090,GO:0098772 - 0.000000000000000000000000000000000001188 147.0
TH2_k127_3579421_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000001219 117.0
TH2_k127_3579421_3 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000008522 111.0
TH2_k127_3579421_4 - - - - 0.0003758 51.0
TH2_k127_3596812_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 1.903e-262 834.0
TH2_k127_3596812_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 568.0
TH2_k127_3596812_2 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 537.0
TH2_k127_3596812_3 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 468.0
TH2_k127_3596812_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 384.0
TH2_k127_3596812_5 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 296.0
TH2_k127_3596812_6 Protein conserved in bacteria K16785 - - 0.00000000000000000000000000000000000000000000000000000009139 198.0
TH2_k127_3596812_8 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000001722 53.0
TH2_k127_3598826_0 DUF based on E. rectale Gene description (DUF3880) K06320 - - 5.413e-218 693.0
TH2_k127_3598826_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 540.0
TH2_k127_3598826_2 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 363.0
TH2_k127_3598826_3 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843,K02849 - - 0.000000000000000000000000000000000000000000000003385 179.0
TH2_k127_3598826_5 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000000000001068 89.0
TH2_k127_3598826_6 FlaG protein K06603 - - 0.0000000009924 64.0
TH2_k127_3600068_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.783e-210 662.0
TH2_k127_3600068_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 541.0
TH2_k127_3604971_0 von Willebrand factor (vWF) type A domain K02448 - - 1.07e-311 979.0
TH2_k127_3604971_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.797e-244 759.0
TH2_k127_3604971_10 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000006443 123.0
TH2_k127_3604971_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 496.0
TH2_k127_3604971_3 Pfam:DUF989 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 373.0
TH2_k127_3604971_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 336.0
TH2_k127_3604971_5 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 321.0
TH2_k127_3604971_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001299 229.0
TH2_k127_3604971_7 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000000000000000000000000000000000000004093 206.0
TH2_k127_3604971_8 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000007707 202.0
TH2_k127_3604971_9 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.00000000000000000000000000000000000000000000000000007244 189.0
TH2_k127_3606508_0 Protein of unknown function, DUF255 K06888 - - 0.0 1641.0
TH2_k127_3606508_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524,K07012 - 3.6.1.11,3.6.1.40 5.485e-209 662.0
TH2_k127_3606508_2 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003764 282.0
TH2_k127_3606508_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000008849 237.0
TH2_k127_3606508_4 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000001107 169.0
TH2_k127_3606508_5 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000008752 151.0
TH2_k127_3606508_6 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000003378 136.0
TH2_k127_3623348_0 von Willebrand factor (vWF) type A domain K02448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 614.0
TH2_k127_3623348_1 ferredoxin-thioredoxin reductase activity K17892 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015979,GO:0016491,GO:0016730,GO:0022900,GO:0030385,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 1.8.7.2 0.0000000000000266 73.0
TH2_k127_3629730_0 FAD binding domain K00239 - 1.3.5.1,1.3.5.4 1.846e-306 941.0
TH2_k127_3629730_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 7.656e-240 743.0
TH2_k127_3629730_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000002128 188.0
TH2_k127_3639826_0 molybdopterin cofactor binding K00370,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4 0.0 1286.0
TH2_k127_3639826_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008247 625.0
TH2_k127_3639826_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 504.0
TH2_k127_3639826_4 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 332.0
TH2_k127_3639826_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000005818 272.0
TH2_k127_3639826_6 - - - - 0.0000002493 54.0
TH2_k127_3656472_0 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 354.0
TH2_k127_3656472_1 Animal haem peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 344.0
TH2_k127_3656472_2 precorrin-2 dehydrogenase activity K02302,K02304 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 329.0
TH2_k127_3656472_3 PFAM AIG2 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006234 267.0
TH2_k127_3656472_4 cytochrome complex assembly K02200,K04018,K19225,K20543,K21007 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000005804 223.0
TH2_k127_3656472_5 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000007088 208.0
TH2_k127_3656472_6 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000000000001277 176.0
TH2_k127_3656472_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000000000000000006682 142.0
TH2_k127_3656472_9 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.000000000000000001081 85.0
TH2_k127_3661131_0 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 324.0
TH2_k127_3661131_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000001676 230.0
TH2_k127_3661131_2 ATPase kinase involved in NAD metabolism - - - 0.00000000000000000000000000000000000000000000000000000000003282 211.0
TH2_k127_3661131_3 response regulator K07814 - - 0.00000000000001546 79.0
TH2_k127_3686753_0 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 500.0
TH2_k127_3686753_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 412.0
TH2_k127_3686753_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000001669 214.0
TH2_k127_3686753_3 DivIVA protein K04074 - - 0.000000000000000000000000000000000000000000000000000000003465 211.0
TH2_k127_3686753_4 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000000000001919 202.0
TH2_k127_3686753_5 YGGT family K02221 - - 0.0000000000000000000000000000000000000000000003933 168.0
TH2_k127_3691451_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 579.0
TH2_k127_3691451_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 385.0
TH2_k127_3691451_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 345.0
TH2_k127_3691451_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001828 235.0
TH2_k127_3691451_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000002513 188.0
TH2_k127_3691451_5 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.00000000000000000000000008967 119.0
TH2_k127_3691451_6 Prokaryotic N-terminal methylation motif K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00000000000000001038 91.0
TH2_k127_3696513_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1128.0
TH2_k127_3696513_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 398.0
TH2_k127_3696513_10 amp-dependent synthetase and ligase - - - 0.0000000000000002596 85.0
TH2_k127_3696513_11 Belongs to the 'phage' integrase family - - - 0.0003415 46.0
TH2_k127_3696513_2 Belongs to the serpin family K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000358 287.0
TH2_k127_3696513_3 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000000000000000000000000000000006042 220.0
TH2_k127_3696513_4 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000008674 207.0
TH2_k127_3696513_5 TIGRFAM addiction module killer protein - - - 0.000000000000000000000000000000000000000000000000002316 183.0
TH2_k127_3696513_6 TIGRFAM addiction module antidote protein - - - 0.00000000000000000000000000000000000000000000008352 173.0
TH2_k127_3696513_7 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000009464 161.0
TH2_k127_3696513_8 Integrase core domain - - - 0.000000000000000000000000000001009 126.0
TH2_k127_3696513_9 peptidyl-tyrosine sulfation - - - 0.000000000000000000002892 103.0
TH2_k127_3704726_0 - - - - 0.000000000000000001554 98.0
TH2_k127_3704726_1 SMART Tetratricopeptide repeat - - - 0.0000000000009432 81.0
TH2_k127_3704881_0 Phage integrase family - - - 0.00000000000000000000000000000000000003154 145.0
TH2_k127_3704881_1 - - - - 0.000000000000000000000000005545 123.0
TH2_k127_3704881_2 - - - - 0.0000000000000002456 90.0
TH2_k127_3705481_0 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 382.0
TH2_k127_3714735_0 Bacterial regulatory protein, Fis family K07715 - - 1.918e-233 731.0
TH2_k127_3714735_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 568.0
TH2_k127_3714735_2 - K07184,K07777,K12065,K13527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000006618 218.0
TH2_k127_3716543_0 oxidoreductase activity K07114 - - 1.982e-243 771.0
TH2_k127_3716543_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 461.0
TH2_k127_3716543_10 phosphorelay signal transduction system - - - 0.0000000000001462 78.0
TH2_k127_3716543_11 - - - - 0.00000002245 57.0
TH2_k127_3716543_2 AcrB/AcrD/AcrF family K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 334.0
TH2_k127_3716543_3 Histidine kinase K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 335.0
TH2_k127_3716543_4 response regulator K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 286.0
TH2_k127_3716543_5 chlorophyll binding K03640 - - 0.000000000000000000000000000000000000000000000000000000000000000000489 237.0
TH2_k127_3716543_6 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000000000000000000001335 228.0
TH2_k127_3716543_7 phosphorelay signal transduction system - - - 0.0000000000000000000000000005433 117.0
TH2_k127_3716543_8 PFAM nuclease (SNase domain protein) - - - 0.00000000000000000000000003999 114.0
TH2_k127_3716543_9 phosphorelay signal transduction system K02535 - 3.5.1.108 0.0000000000000000000003183 105.0
TH2_k127_3724050_0 homolog of phage Mu protein gp47 - - - 5.318e-235 755.0
TH2_k127_3724050_1 Baseplate J-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 484.0
TH2_k127_3724050_2 Gene 25-like lysozyme K06903 - - 0.0006911 42.0
TH2_k127_373674_0 Sugar (and other) transporter K08178 - - 8.299e-214 670.0
TH2_k127_373674_1 imidazolonepropionase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 362.0
TH2_k127_373674_2 heat shock protein binding K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 305.0
TH2_k127_3742206_0 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000001554 215.0
TH2_k127_3780132_0 FtsX-like permease family K02004 - - 0.0 1057.0
TH2_k127_3780132_1 Histidine Phosphotransfer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008881 453.0
TH2_k127_3780132_2 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 329.0
TH2_k127_3780132_3 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000001698 252.0
TH2_k127_3780132_4 Peptidase family M1 domain K08776 - - 0.0000000000000000000000000000000000000000000001093 170.0
TH2_k127_3780132_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000001658 116.0
TH2_k127_3780132_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000003433 98.0
TH2_k127_3792332_0 Type II/IV secretion system protein K02454,K02652 - - 6.254e-227 725.0
TH2_k127_3792332_1 Pilus assembly protein PilX K07140 - - 0.000000000000000000000000000000000000000000000000000006192 196.0
TH2_k127_3792332_2 pilus assembly protein PilW K02672 - - 0.0000000000000000000000000000000000006207 151.0
TH2_k127_3792332_3 type IV pilus modification protein PilV K02671,K02681,K10927 - - 0.0000000000000000000000002132 112.0
TH2_k127_3792332_4 Prokaryotic N-terminal methylation motif K08084,K08085 - - 0.0002252 51.0
TH2_k127_379541_0 heat shock protein binding - - - 9.123e-232 749.0
TH2_k127_379541_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 482.0
TH2_k127_379541_2 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 312.0
TH2_k127_379541_3 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003215 263.0
TH2_k127_379541_5 cellulase activity - - - 0.00000000000000000000000000000004348 142.0
TH2_k127_379541_6 Psort location Extracellular, score - - - 0.00000000000000000009107 100.0
TH2_k127_381151_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 4.486e-195 623.0
TH2_k127_381151_1 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 428.0
TH2_k127_381151_10 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.0000000000000005843 85.0
TH2_k127_381151_11 protein transport across the cell outer membrane K02246,K02457,K02459,K02672,K08084 - - 0.000000000000001112 85.0
TH2_k127_381151_12 Pilus assembly protein K02461,K02662,K02663,K12289 - - 0.00000000000001774 87.0
TH2_k127_381151_14 overlaps another CDS with the same product name K02458 - - 0.000000000235 69.0
TH2_k127_381151_15 DNA excision K02806 - - 0.000000006051 66.0
TH2_k127_381151_16 pilus assembly protein PilW K02459 - - 0.00000158 58.0
TH2_k127_381151_19 Wd-40 repeat - - - 0.000179 51.0
TH2_k127_381151_2 Bacterial type II and III secretion system protein K02453,K03219 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 428.0
TH2_k127_381151_3 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 397.0
TH2_k127_381151_4 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 392.0
TH2_k127_381151_5 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000000000002991 205.0
TH2_k127_381151_6 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000001025 174.0
TH2_k127_381151_7 protein secretion K02460 - - 0.000000000000000000000000196 119.0
TH2_k127_381151_8 translation initiation factor activity K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000002306 99.0
TH2_k127_381151_9 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000003524 96.0
TH2_k127_381197_0 - - - - 0.000000000000000000000324 103.0
TH2_k127_3812346_0 MFS_1 like family - - - 5.401e-194 613.0
TH2_k127_3812346_1 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 325.0
TH2_k127_3812346_2 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 316.0
TH2_k127_3812346_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000001594 115.0
TH2_k127_3812346_5 OmpA family K02557 - - 0.00000000000000000000000122 114.0
TH2_k127_3812346_6 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000001318 100.0
TH2_k127_3816547_0 Nitroreductase - - - 1.022e-212 668.0
TH2_k127_3819034_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 9.886e-296 917.0
TH2_k127_3819034_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.509e-252 781.0
TH2_k127_3819034_10 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 436.0
TH2_k127_3819034_11 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 383.0
TH2_k127_3819034_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 389.0
TH2_k127_3819034_13 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 379.0
TH2_k127_3819034_14 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 379.0
TH2_k127_3819034_15 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 387.0
TH2_k127_3819034_16 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 337.0
TH2_k127_3819034_17 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 311.0
TH2_k127_3819034_18 protein secretion K03116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 292.0
TH2_k127_3819034_19 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000000000000000000000000000001243 244.0
TH2_k127_3819034_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 4.277e-221 698.0
TH2_k127_3819034_20 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000002861 229.0
TH2_k127_3819034_21 ParB-like nuclease domain - - - 0.00000000000000000000000000000000000000000000000000000000000002008 224.0
TH2_k127_3819034_22 peptidase K02557,K21471 - - 0.00000000000000000000000000000000000000000000000000000001597 212.0
TH2_k127_3819034_23 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000002825 194.0
TH2_k127_3819034_24 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000008914 194.0
TH2_k127_3819034_25 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000000000003586 189.0
TH2_k127_3819034_26 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000007954 179.0
TH2_k127_3819034_27 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000001908 163.0
TH2_k127_3819034_28 deoxyhypusine monooxygenase activity K05386 - - 0.00000000000000000000000000000000207 139.0
TH2_k127_3819034_29 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000003985 136.0
TH2_k127_3819034_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 2.528e-212 664.0
TH2_k127_3819034_30 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000000000000000000000000001264 112.0
TH2_k127_3819034_31 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000007509 108.0
TH2_k127_3819034_34 - - - - 0.00000000003171 72.0
TH2_k127_3819034_35 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000001587 63.0
TH2_k127_3819034_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.049e-196 620.0
TH2_k127_3819034_5 Peptidase family M1 domain K08776 - - 1.358e-195 621.0
TH2_k127_3819034_6 proline dipeptidase activity K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 578.0
TH2_k127_3819034_7 Glucokinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 536.0
TH2_k127_3819034_8 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 497.0
TH2_k127_3819034_9 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 449.0
TH2_k127_3839759_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1127.0
TH2_k127_3839759_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 5.939e-236 735.0
TH2_k127_3839759_2 RNA recognition motif - - - 0.0000000000000000000000000000000000000000006446 160.0
TH2_k127_3839759_3 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000002586 147.0
TH2_k127_3839759_4 Domain of unknown function (DUF4321) - - - 0.0000000000000000000000000000003823 126.0
TH2_k127_3839759_5 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000001655 111.0
TH2_k127_3898220_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 389.0
TH2_k127_3898220_1 Domain of unknown function (DUF4112) - - - 0.00000000000000000000002062 104.0
TH2_k127_3898220_2 Histidine kinase - - - 0.00000000000000000001162 96.0
TH2_k127_392194_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 481.0
TH2_k127_392194_1 glycosyl transferase - - - 0.0000000000000000000000004953 108.0
TH2_k127_3941085_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 430.0
TH2_k127_3941085_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 412.0
TH2_k127_3941085_2 phosphoprotein phosphatase activity K01525 GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 316.0
TH2_k127_3941085_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000005929 229.0
TH2_k127_3941085_4 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000000000000000000000000000004552 169.0
TH2_k127_3980807_0 Major facilitator Superfamily K08218 - - 1.057e-256 801.0
TH2_k127_3980807_1 Evidence 4 Homologs of previously reported genes of K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 527.0
TH2_k127_3980807_2 Dimerisation domain K21377 - 2.1.1.302 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 505.0
TH2_k127_3980807_3 electron transfer activity K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 385.0
TH2_k127_3980807_4 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K00567,K01247 - 2.1.1.63,3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 310.0
TH2_k127_3980807_5 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002476 240.0
TH2_k127_3980807_6 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000376 210.0
TH2_k127_3987343_0 ABC transporter K06158 - - 1.322e-313 968.0
TH2_k127_3987343_1 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 593.0
TH2_k127_3987343_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000001332 165.0
TH2_k127_4036523_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 464.0
TH2_k127_4036523_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001338 271.0
TH2_k127_4036523_2 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000006514 246.0
TH2_k127_4036523_3 Mo-molybdopterin cofactor metabolic process K03636 - - 0.0000000000000000000000000000000007638 139.0
TH2_k127_4049247_0 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 509.0
TH2_k127_4049247_1 Domain of unknown function DUF83 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002954 254.0
TH2_k127_4049247_2 TIGRFAM CRISPR-associated helicase Cas3 K07012 - - 0.000000000000000000000000000000000000000000000000000000000000005735 226.0
TH2_k127_4049247_3 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.0000000000000000000000000000000000000002471 152.0
TH2_k127_4049247_4 domain, Protein - - - 0.000000000000000000000000000000000001138 141.0
TH2_k127_4049247_5 Domain of unknown function (DUF4926) - - - 0.0000000000000000009148 87.0
TH2_k127_4050523_0 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 561.0
TH2_k127_4050523_1 Lipase (class 3) - - - 0.00000002687 58.0
TH2_k127_4053703_0 protein secretion by the type I secretion system K02021 - - 5.533e-285 883.0
TH2_k127_4053703_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 3.493e-280 870.0
TH2_k127_4053703_10 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 499.0
TH2_k127_4053703_11 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 464.0
TH2_k127_4053703_12 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 441.0
TH2_k127_4053703_13 Protein of unknown function (DUF692) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 444.0
TH2_k127_4053703_14 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 430.0
TH2_k127_4053703_15 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 403.0
TH2_k127_4053703_16 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01665 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 374.0
TH2_k127_4053703_17 arginine decarboxylase activity K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 354.0
TH2_k127_4053703_18 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 351.0
TH2_k127_4053703_19 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 347.0
TH2_k127_4053703_2 FAD binding domain K00278 - 1.4.3.16 3.046e-262 821.0
TH2_k127_4053703_20 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 317.0
TH2_k127_4053703_22 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 291.0
TH2_k127_4053703_23 signal-transduction protein containing cAMP-binding and CBS domains K00031,K14446 - 1.1.1.42,1.3.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004698 278.0
TH2_k127_4053703_24 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000174 266.0
TH2_k127_4053703_25 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000307 229.0
TH2_k127_4053703_26 maF-like protein K03215,K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 2.1.1.190 0.000000000000000000000000000000000000000000000000000000003679 206.0
TH2_k127_4053703_28 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000002037 138.0
TH2_k127_4053703_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 1.581e-253 787.0
TH2_k127_4053703_30 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00000000000000000000000000000006249 125.0
TH2_k127_4053703_31 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000006972 121.0
TH2_k127_4053703_4 efflux transmembrane transporter activity - - - 5.005e-232 728.0
TH2_k127_4053703_5 Aldehyde dehydrogenase family - - - 2.519e-215 677.0
TH2_k127_4053703_6 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 606.0
TH2_k127_4053703_7 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 549.0
TH2_k127_4053703_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 526.0
TH2_k127_4053703_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 539.0
TH2_k127_4056378_0 Domain of unknown function (DUF4143) K07133 - - 3.818e-233 729.0
TH2_k127_4056378_1 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000009647 188.0
TH2_k127_4057923_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 518.0
TH2_k127_4057923_1 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.000000000000000000000000000000000000000000000000000000002615 203.0
TH2_k127_4057923_2 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563,K13626 - - 0.000000000002437 67.0
TH2_k127_4114043_0 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 454.0
TH2_k127_4114043_1 bacterial-type flagellum organization K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 413.0
TH2_k127_4114043_3 Flagellar protein FliS K02422 - - 0.000000000000000000000000000000000000000001819 159.0
TH2_k127_4114043_4 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000007709 173.0
TH2_k127_4114043_5 DNA excision K02806 - - 0.000000000000000000000001322 105.0
TH2_k127_4114043_6 Chemotaxis protein methyltransferase K00575 - 2.1.1.80 0.00000001055 57.0
TH2_k127_4156602_0 metallopeptidase activity K01993,K13408,K16922 - - 5.929e-228 723.0
TH2_k127_4156602_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 548.0
TH2_k127_4169022_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000005449 166.0
TH2_k127_4169022_1 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000003147 146.0
TH2_k127_4169022_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03972 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.00000000000000000000000001897 111.0
TH2_k127_4169022_3 domain protein - - - 0.000000004155 62.0
TH2_k127_4191140_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1137.0
TH2_k127_4191140_1 Major Facilitator Superfamily K03446 - - 1.181e-308 949.0
TH2_k127_4191140_2 Evidence 2b Function of strongly homologous gene - - - 6.443e-262 817.0
TH2_k127_4191140_3 HlyD membrane-fusion protein of T1SS K03543 - - 5.363e-208 655.0
TH2_k127_4191140_4 formate transmembrane transporter activity K02598,K06212,K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 439.0
TH2_k127_4191140_5 tungstate binding K02020 - - 0.0000000000000000000000000000000000000000000000003242 187.0
TH2_k127_4201110_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.583e-320 992.0
TH2_k127_4201110_1 efflux transmembrane transporter activity K12340 - - 9.205e-230 721.0
TH2_k127_4201110_2 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 621.0
TH2_k127_4201110_3 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 553.0
TH2_k127_4201110_4 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 533.0
TH2_k127_4201110_7 - - - - 0.00000000000000000000000000000000000000000000001039 173.0
TH2_k127_4201110_8 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000001039 157.0
TH2_k127_4214539_0 protein conserved in bacteria K09859 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 597.0
TH2_k127_4214539_1 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 430.0
TH2_k127_4214539_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000000000000000000001491 237.0
TH2_k127_4219505_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 473.0
TH2_k127_4219505_1 Acetohydroxy acid isomeroreductase, NADPH-binding domain K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 390.0
TH2_k127_4219505_2 Domain of unknown function (DUF1772) - - - 0.000000000000000000000000000000000000000000000000000004889 195.0
TH2_k127_4219505_3 Glutamine cyclotransferase - - - 0.000000000000000000000000000000000000000000004368 163.0
TH2_k127_4225925_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 342.0
TH2_k127_4248335_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 9.126e-213 672.0
TH2_k127_4248335_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 388.0
TH2_k127_4248335_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000003868 133.0
TH2_k127_4248335_3 Aminotransferase class I and II K14261 - - 0.00000000000000000000001607 99.0
TH2_k127_4266091_0 AcrB/AcrD/AcrF family - - - 0.0 1412.0
TH2_k127_4266091_1 Cytochrome b/b6/petB K00412,K03888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 502.0
TH2_k127_4266091_2 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 439.0
TH2_k127_4293203_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 2.764e-284 891.0
TH2_k127_4293203_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 529.0
TH2_k127_4293203_10 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.000000000000000739 78.0
TH2_k127_4293203_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 479.0
TH2_k127_4293203_3 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 460.0
TH2_k127_4293203_4 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 413.0
TH2_k127_4293203_6 sodium:proton antiporter activity K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 312.0
TH2_k127_4293203_7 translation initiation factor activity K03407,K03646,K04065,K06596,K07277,K12065,K13593 - 2.7.13.3 0.00000000000000000000000000000000001016 151.0
TH2_k127_4293203_9 Protein of unknown function (DUF421) - - - 0.000000000000000000006552 96.0
TH2_k127_431428_0 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 323.0
TH2_k127_431428_2 helicase activity K06915 - - 0.000000000000000000000000004404 118.0
TH2_k127_431428_3 Protein of unknown function (DUF1353) - - - 0.00000000000000000000004717 106.0
TH2_k127_431428_4 - - - - 0.0000000000000000611 81.0
TH2_k127_431428_5 hmm pf02371 K07486 - - 0.00000000000005738 73.0
TH2_k127_431428_6 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00002173 48.0
TH2_k127_4348742_0 tail specific protease K03797 - 3.4.21.102 2.919e-208 657.0
TH2_k127_4348742_1 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 472.0
TH2_k127_4348742_2 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 368.0
TH2_k127_4348742_3 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.00000000000000000000000000000000000000000000009698 171.0
TH2_k127_4365305_0 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 439.0
TH2_k127_4365305_1 tRNA 3'-trailer cleavage - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 364.0
TH2_k127_4365305_2 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000000000000000000000000000000000000000003306 211.0
TH2_k127_4365305_3 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000006358 187.0
TH2_k127_4383151_0 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 420.0
TH2_k127_4383151_1 sialic acid-specific 9-O-acetylesterase K10804 - 3.1.1.5 0.0000000000000000001167 97.0
TH2_k127_4404046_0 - - - - 0.00000000000000000000000000000000000000000000000000002256 208.0
TH2_k127_4404046_1 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000005719 114.0
TH2_k127_4404046_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K00575 - 2.1.1.80 0.0000000002329 61.0
TH2_k127_4404046_3 Antibiotic biosynthesis monooxygenase - - - 0.00000008045 56.0
TH2_k127_44140_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 8.079e-248 767.0
TH2_k127_44140_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 594.0
TH2_k127_44140_2 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 556.0
TH2_k127_44140_3 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 479.0
TH2_k127_44140_4 nucleotidyltransferase activity K00984,K19279 - 2.7.7.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 292.0
TH2_k127_44140_5 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000001982 226.0
TH2_k127_44140_7 ThiS family K03636 - - 0.000000000000000000000000000000000000003644 147.0
TH2_k127_44140_8 thiamine diphosphate biosynthetic process K03154 - - 0.0000000000000000000000000341 109.0
TH2_k127_4444247_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 525.0
TH2_k127_4444247_1 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 329.0
TH2_k127_4444247_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 294.0
TH2_k127_4444247_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000008574 72.0
TH2_k127_4472684_0 Glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.0 1509.0
TH2_k127_4472684_1 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 1.605e-287 890.0
TH2_k127_4472684_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 2.127e-219 689.0
TH2_k127_4472684_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 395.0
TH2_k127_4472684_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000001731 130.0
TH2_k127_4472684_5 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000198 100.0
TH2_k127_448272_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.459e-264 819.0
TH2_k127_448272_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 4.451e-225 705.0
TH2_k127_448272_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 467.0
TH2_k127_448272_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 326.0
TH2_k127_448272_4 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003113 257.0
TH2_k127_4492465_0 NADH-quinone oxidoreductase K00341 - 1.6.5.3 5e-324 999.0
TH2_k127_4492465_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 3.533e-236 739.0
TH2_k127_4492465_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 8.537e-215 677.0
TH2_k127_4492465_3 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 494.0
TH2_k127_4492465_4 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 344.0
TH2_k127_4492465_5 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 310.0
TH2_k127_4492465_6 acetyltransferase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000542 215.0
TH2_k127_4492465_7 Glyoxalase-like domain K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000005742 188.0
TH2_k127_4492465_8 phosphorelay sensor kinase activity K16923 - - 0.00000002016 67.0
TH2_k127_4498044_0 - - - - 0.00000000000000000000000000000000000001288 150.0
TH2_k127_4498044_1 - - - - 0.0000000000001643 72.0
TH2_k127_4498044_2 Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01886 - 6.1.1.18 0.0000000000004024 69.0
TH2_k127_4498044_3 tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity K18055 - 1.14.11.30 0.000007758 52.0
TH2_k127_4498044_4 - - - - 0.0007525 51.0
TH2_k127_4509472_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 453.0
TH2_k127_4509472_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 436.0
TH2_k127_4509472_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 388.0
TH2_k127_4509472_3 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 363.0
TH2_k127_4509472_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000006132 143.0
TH2_k127_4509472_6 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.000000000000005883 78.0
TH2_k127_4515321_0 SMART serine threonine protein kinase - - - 7.033e-227 748.0
TH2_k127_4515321_1 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000009561 156.0
TH2_k127_4515321_2 - - - - 0.00000000000006543 78.0
TH2_k127_4515321_3 Forkhead associated domain - - - 0.0000000008663 64.0
TH2_k127_4521050_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 1.581e-228 710.0
TH2_k127_4521050_1 - - - - 0.0000000000000000000000000000000000004771 154.0
TH2_k127_4521050_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000001311 99.0
TH2_k127_4544518_0 Beta-Casp domain K07576 - - 3.487e-208 652.0
TH2_k127_4544518_1 aminopeptidase activity K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 576.0
TH2_k127_4544518_2 FIST C domain - GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 445.0
TH2_k127_4549091_0 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007181 289.0
TH2_k127_4549091_1 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001458 276.0
TH2_k127_4549091_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000001364 150.0
TH2_k127_4549091_3 Belongs to the UPF0173 family - - - 0.0008989 42.0
TH2_k127_4554434_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 384.0
TH2_k127_4554434_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000004551 162.0
TH2_k127_4554434_2 phosphorelay signal transduction system - - - 0.000000000002438 66.0
TH2_k127_4572128_0 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 440.0
TH2_k127_4572128_1 serine-type aminopeptidase activity K02030,K14475 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 345.0
TH2_k127_4572128_2 Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 313.0
TH2_k127_4572128_3 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002366 254.0
TH2_k127_4572128_4 deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003002 248.0
TH2_k127_4572128_5 Cupin domain - - - 0.000000000000000000000000000000000000000002057 160.0
TH2_k127_4577336_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 1.263e-244 760.0
TH2_k127_4577336_1 Histidyl-tRNA synthetase K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 464.0
TH2_k127_4577336_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 419.0
TH2_k127_4577336_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 283.0
TH2_k127_4584666_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 1.101e-229 716.0
TH2_k127_4584666_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.474e-229 717.0
TH2_k127_4584666_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 505.0
TH2_k127_4584666_3 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 304.0
TH2_k127_4584666_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 290.0
TH2_k127_4584666_6 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000006404 241.0
TH2_k127_4584666_7 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000005523 225.0
TH2_k127_4584666_8 TIGRFAM tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000002044 211.0
TH2_k127_4584666_9 Belongs to the 'phage' integrase family - - - 0.000000151 52.0
TH2_k127_4597121_0 Outer membrane efflux protein - - - 1.53e-226 713.0
TH2_k127_4597121_1 phosphoserine phosphatase activity K02668,K07710,K07711,K10942 - 2.7.13.3 3.374e-217 692.0
TH2_k127_4597121_2 phosphorelay signal transduction system - - - 7.073e-204 643.0
TH2_k127_4597121_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 495.0
TH2_k127_4597121_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 407.0
TH2_k127_4597121_5 Histidine kinase - - - 0.00000000000000000000000005009 109.0
TH2_k127_4604656_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 2.339e-211 659.0
TH2_k127_4604656_1 PFAM ABC transporter transmembrane region K06147 - - 1.745e-201 643.0
TH2_k127_4604656_10 CMP-N-acetylneuraminic acid synthetase - - - 0.00000000000000000000000000000000000000000000000000000002311 202.0
TH2_k127_4604656_11 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000002874 107.0
TH2_k127_4604656_2 Belongs to the DegT DnrJ EryC1 family - - - 1.758e-197 622.0
TH2_k127_4604656_3 Polysaccharide biosynthesis protein - - - 2.192e-194 609.0
TH2_k127_4604656_4 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 597.0
TH2_k127_4604656_5 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009055 477.0
TH2_k127_4604656_6 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 316.0
TH2_k127_4604656_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002694 269.0
TH2_k127_4604656_8 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004943 262.0
TH2_k127_4604656_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000231 226.0
TH2_k127_4619750_0 Heavy-metal-associated domain K17686 - 3.6.3.54 0.0 1011.0
TH2_k127_4619750_1 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 354.0
TH2_k127_4619750_2 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 322.0
TH2_k127_4622765_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 479.0
TH2_k127_4622765_1 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 411.0
TH2_k127_4638459_0 ABC transporter K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 420.0
TH2_k127_4638459_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 285.0
TH2_k127_4638459_2 Oxidoreductase - - - 0.000000000000000000001526 95.0
TH2_k127_4638459_3 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000009364 81.0
TH2_k127_4649143_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 364.0
TH2_k127_4649143_2 zinc ion binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000989 252.0
TH2_k127_4649143_4 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.00001771 48.0
TH2_k127_4653523_0 COG2801 Transposase and inactivated derivatives K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 442.0
TH2_k127_4653523_1 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000007312 259.0
TH2_k127_4653523_2 - - - - 0.0000000001764 72.0
TH2_k127_4653523_3 - - - - 0.00000005426 58.0
TH2_k127_468993_0 Baseplate J-like protein - - - 0.0 1360.0
TH2_k127_468993_1 Late control gene D protein - - - 6.319e-225 700.0
TH2_k127_468993_10 - - - - 0.000000000000000000000000000000000000000000000000000005634 191.0
TH2_k127_468993_11 Gene 25-like lysozyme K06903 - - 0.000000000000000000000000000000000000000000001335 168.0
TH2_k127_468993_12 PAAR repeat-containing protein - - - 0.000000000000000000000000000000000000007715 146.0
TH2_k127_468993_13 - - - - 0.000000000000004083 76.0
TH2_k127_468993_2 Baseplate J-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 520.0
TH2_k127_468993_3 Phage tail sheath C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 459.0
TH2_k127_468993_4 Rhs element vgr protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 340.0
TH2_k127_468993_5 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 305.0
TH2_k127_468993_6 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000002288 214.0
TH2_k127_468993_7 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000000000000004457 218.0
TH2_k127_468993_8 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000002894 211.0
TH2_k127_468993_9 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000001579 211.0
TH2_k127_4690027_0 Insecticide toxin TcdB middle/N-terminal region - - - 6.784e-241 756.0
TH2_k127_4690027_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004106 276.0
TH2_k127_4690027_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000003633 241.0
TH2_k127_4690027_3 Domain of unknown function (DUF4131) K02238 - - 0.00000000000000000000000000000000001115 142.0
TH2_k127_4690027_4 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000001433 69.0
TH2_k127_4691047_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000002488 189.0
TH2_k127_4691047_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000001102 182.0
TH2_k127_4691047_2 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000007266 178.0
TH2_k127_4691047_3 PFAM EamA-like transporter family - - - 0.0000001193 63.0
TH2_k127_4699380_0 twitching motility protein K02670 - - 3.251e-216 675.0
TH2_k127_4699380_1 Type II/IV secretion system protein K02669 - - 1.464e-205 642.0
TH2_k127_4699380_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 8.241e-204 638.0
TH2_k127_4699380_3 Evidence 2b Function of strongly homologous gene - - - 5.672e-202 634.0
TH2_k127_4699380_4 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 529.0
TH2_k127_4699380_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0030312,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 512.0
TH2_k127_4699380_6 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 394.0
TH2_k127_4699380_7 cell envelope organization K05807,K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 331.0
TH2_k127_4699380_8 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000000009537 199.0
TH2_k127_4699380_9 Cytochrome c K00405 - - 0.0000000000000000000000000000000000000000000002083 173.0
TH2_k127_4713837_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 320.0
TH2_k127_4713837_1 diguanylate cyclase - - - 0.0000000000007527 71.0
TH2_k127_4739014_0 Sigma-70, region 4 K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 354.0
TH2_k127_4739014_1 Cellulose biosynthesis protein BcsQ K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 345.0
TH2_k127_4754255_0 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001757 220.0
TH2_k127_4754255_1 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000001714 130.0
TH2_k127_4788381_0 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.0 1200.0
TH2_k127_4788381_1 DNA methylase K07316 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 379.0
TH2_k127_4788381_2 DNA polymerase beta domain protein region K07075 - - 0.000000000000000000000000000003194 123.0
TH2_k127_4788381_3 Protein of unknown function DUF86 K07075 - - 0.0000000000000000000201 97.0
TH2_k127_4788381_4 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 0.00007549 48.0
TH2_k127_4811126_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.251e-265 835.0
TH2_k127_4811126_1 Sigma-54 interaction domain K07714 - - 8.567e-223 698.0
TH2_k127_4811126_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 466.0
TH2_k127_4811126_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 307.0
TH2_k127_4811126_5 sequence-specific DNA binding - - - 0.0000000000000000000000000000785 120.0
TH2_k127_4859713_0 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 414.0
TH2_k127_4859713_1 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 298.0
TH2_k127_4859713_2 protein disulfide oxidoreductase activity K07390 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000002788 206.0
TH2_k127_4859713_4 Belongs to the BolA IbaG family K05527,K22066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0019538,GO:0022603,GO:0022604,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051604,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097428,GO:0097659,GO:0106035,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.00000000000000000000008364 101.0
TH2_k127_4859901_0 pteridine-dependent deoxygenase K18240 - 4.1.3.40,4.1.3.45 0.00000000000000000000000000000000000000000000000000000000000008233 228.0
TH2_k127_4859901_1 Polysaccharide deacetylase - - - 0.0000000000000000003598 98.0
TH2_k127_4859901_2 oxidoreductase K14257 - 1.14.19.49 0.000000000003615 70.0
TH2_k127_4868399_0 Cellulose synthase K00694,K20541 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 310.0
TH2_k127_4868399_1 NADH-quinone oxidoreductase K00341,K05577 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000522 191.0
TH2_k127_4886975_0 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 4.946e-269 836.0
TH2_k127_4893680_0 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 586.0
TH2_k127_4893680_2 NmrA-like family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 539.0
TH2_k127_4893680_3 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 389.0
TH2_k127_4893680_4 Cytochrome c K03611 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 285.0
TH2_k127_4893680_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009693 248.0
TH2_k127_4893680_6 - K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000002621 226.0
TH2_k127_4896021_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000000000004885 199.0
TH2_k127_4896021_1 positive regulation of growth - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000001024 140.0
TH2_k127_4896021_2 Beta-propeller repeat - - - 0.00000003059 64.0
TH2_k127_4896021_3 - - - - 0.0001373 48.0
TH2_k127_4905016_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1020.0
TH2_k127_4905016_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 4.944e-210 655.0
TH2_k127_4939008_0 glutamate-tRNA ligase activity K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 8.593e-317 979.0
TH2_k127_4939008_1 Alcohol dehydrogenase GroES-like domain K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 497.0
TH2_k127_4939008_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.00000000000000000000000000000000000002125 155.0
TH2_k127_4939008_11 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000005415 74.0
TH2_k127_4939008_15 DNA integration - - - 0.00004633 46.0
TH2_k127_4939008_2 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 407.0
TH2_k127_4939008_3 Twin-arginine translocation pathway signal sequence - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 364.0
TH2_k127_4939008_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001297 235.0
TH2_k127_4939008_5 lactoylglutathione lyase activity K01759 GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000005997 237.0
TH2_k127_4939008_6 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000001033 221.0
TH2_k127_4939008_7 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000002962 197.0
TH2_k127_4939008_9 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.000000000000000000000000000000000000006029 153.0
TH2_k127_4951074_0 HsdM N-terminal domain K03427 - 2.1.1.72 1.829e-202 634.0
TH2_k127_4951074_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 368.0
TH2_k127_4951074_2 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 319.0
TH2_k127_4951074_3 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000785 299.0
TH2_k127_4958822_0 E-Z type HEAT repeats - - - 0.00000000000000000000000000000000000000000000000002989 192.0
TH2_k127_4958822_1 Response regulator receiver domain - - - 0.0000000000000000000000002149 107.0
TH2_k127_4965598_0 lipopolysaccharide transport K22110 - - 0.0 1549.0
TH2_k127_4965598_1 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 549.0
TH2_k127_4965598_10 Protein of unknown function (DUF3565) - - - 0.000000000000000000000000001088 112.0
TH2_k127_4965598_11 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000008915 94.0
TH2_k127_4965598_13 PFAM Lon protease (S16) C-terminal proteolytic domain K06870 - - 0.000003416 57.0
TH2_k127_4965598_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 498.0
TH2_k127_4965598_3 phosphorelay signal transduction system K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 490.0
TH2_k127_4965598_4 pectinesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 451.0
TH2_k127_4965598_5 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 449.0
TH2_k127_4965598_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001427 274.0
TH2_k127_4965598_7 - K11477 - - 0.0000000000000000000000000000000000000000000000000000000000000000005145 232.0
TH2_k127_4965598_8 negative regulation of translational initiation K05554,K14670,K15886 - 2.3.1.235 0.000000000000000000000000000000000000000000000000000000001698 206.0
TH2_k127_4970126_0 Transposase IS116/IS110/IS902 family - GO:0003674,GO:0003824,GO:0004803,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0032196,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 380.0
TH2_k127_4985451_0 Cytochrome c - - - 4.441e-248 771.0
TH2_k127_4985451_1 - - - - 0.0000009194 55.0
TH2_k127_4992107_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 4.176e-218 697.0
TH2_k127_4992107_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 383.0
TH2_k127_4992107_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 289.0
TH2_k127_4992107_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03673 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071236,GO:0140096 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001895 280.0
TH2_k127_4992107_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07285 - - 0.000000000000000000000000000000000000000000000000000000000381 209.0
TH2_k127_5011127_0 Endoribonuclease that initiates mRNA decay K18682 - - 3.141e-255 795.0
TH2_k127_5011127_1 Transglycosylase SLT domain K08309 - - 2.389e-252 800.0
TH2_k127_5011127_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 477.0
TH2_k127_5011127_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 469.0
TH2_k127_5011127_4 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 440.0
TH2_k127_5011127_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 421.0
TH2_k127_5011127_6 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 370.0
TH2_k127_5011127_7 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 300.0
TH2_k127_5011127_8 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000000006662 130.0
TH2_k127_5011127_9 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.0000000000000000000000000004604 115.0
TH2_k127_5021338_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 9.038e-224 698.0
TH2_k127_5021338_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 432.0
TH2_k127_5021338_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000003753 209.0
TH2_k127_5021338_5 Immunoglobulin-like domain of bacterial spore germination - - - 0.000000000000000000000000000004291 126.0
TH2_k127_510262_0 Rubrerythrin K22405 - 1.6.3.4 0.0 1232.0
TH2_k127_510262_1 Elongator protein 3, MiaB family, Radical SAM - - - 1.84e-316 973.0
TH2_k127_510262_10 TRL-like protein family - - - 0.000000000000001939 79.0
TH2_k127_510262_2 Iron-sulfur cluster-binding domain - - - 6.831e-286 881.0
TH2_k127_510262_3 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 546.0
TH2_k127_510262_4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 386.0
TH2_k127_510262_5 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 307.0
TH2_k127_510262_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000001348 187.0
TH2_k127_510262_8 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000004822 163.0
TH2_k127_510262_9 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000132 156.0
TH2_k127_5128661_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 443.0
TH2_k127_5128661_1 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 315.0
TH2_k127_5128661_2 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000001047 249.0
TH2_k127_5128661_3 Adenosylcobinamide amidohydrolase K02013,K02231 - 2.7.1.156,2.7.7.62,3.6.3.34 0.0001134 46.0
TH2_k127_5131534_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 4.561e-230 728.0
TH2_k127_5131534_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 350.0
TH2_k127_5131534_2 cheY-homologous receiver domain K02658 - - 0.00000000000000000000000000000000000000000000000000000000000000000008368 231.0
TH2_k127_5131534_3 Two component signalling adaptor domain K02487,K06596 - - 0.0000000000000000000000000000000000000000000000006201 184.0
TH2_k127_5131534_4 chemotaxis K03408,K03415 - - 0.000000000000000000000000000000000000004082 151.0
TH2_k127_5139208_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 2267.0
TH2_k127_5139208_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 567.0
TH2_k127_5139208_2 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 437.0
TH2_k127_5139208_3 chlorophyll binding K02487,K12543 - - 0.00000000000000000000000000000000000000000000000000000000000000003628 231.0
TH2_k127_5139208_7 RNA-binding protein - - - 0.000000005035 63.0
TH2_k127_5139208_8 Helix-hairpin-helix motif - - - 0.000000005111 62.0
TH2_k127_51634_0 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000001226 174.0
TH2_k127_51634_1 CBS domain K04767 - - 0.00000000000000000000000000000000000000000002053 168.0
TH2_k127_51634_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000004131 144.0
TH2_k127_51634_3 - - - - 0.0000000000000000000002405 100.0
TH2_k127_5170152_0 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 507.0
TH2_k127_5170152_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001845 270.0
TH2_k127_5170152_3 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000003001 236.0
TH2_k127_5170152_4 Histidine kinase K07683 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000002362 230.0
TH2_k127_5170152_5 regulation of translation K03704,K05809 - - 0.0000000000000000000000000000000000004286 141.0
TH2_k127_5170152_6 phosphoribosyltransferase K07100 - - 0.000000000006031 66.0
TH2_k127_5170152_7 Dienelactone hydrolase - - - 0.0000003915 55.0
TH2_k127_5174069_0 Serine Threonine protein kinase K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 373.0
TH2_k127_5174069_1 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 306.0
TH2_k127_5174069_2 PFAM AIG2 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001843 263.0
TH2_k127_5174069_3 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000062 203.0
TH2_k127_5174069_4 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.0000000000000000000000000000000000000004828 149.0
TH2_k127_5195281_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1125.0
TH2_k127_5195281_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 533.0
TH2_k127_5195281_2 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 503.0
TH2_k127_5195281_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 493.0
TH2_k127_5195281_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 477.0
TH2_k127_5195281_5 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008027 272.0
TH2_k127_5195281_6 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000005599 248.0
TH2_k127_5195281_7 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000000000000000000000000000000000000003985 216.0
TH2_k127_5195281_8 Mo-molybdopterin cofactor metabolic process K03636 - - 0.000000000000000000000000000007592 128.0
TH2_k127_5195281_9 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000003064 61.0
TH2_k127_5245122_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 1.471e-236 756.0
TH2_k127_5245122_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002226 242.0
TH2_k127_5245122_2 membrane transporter protein K07090 - - 0.00000000000000001002 84.0
TH2_k127_5252114_0 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 330.0
TH2_k127_5252114_1 COG0454 Histone acetyltransferase HPA2 and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002485 269.0
TH2_k127_5252114_2 Conserved TM helix - - - 0.000000000000000000000000000000000000000000000000000000004804 207.0
TH2_k127_5252114_3 O-acyltransferase activity - - - 0.0000000000000000000000009359 110.0
TH2_k127_5288305_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 603.0
TH2_k127_5288305_1 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000002066 228.0
TH2_k127_5294061_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 2.08e-210 663.0
TH2_k127_5294061_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 9.034e-202 637.0
TH2_k127_5294061_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 563.0
TH2_k127_5294061_3 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 362.0
TH2_k127_5294061_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000003402 254.0
TH2_k127_5294061_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000001058 234.0
TH2_k127_5294061_6 protein trimerization K01206,K07114,K07126 - 3.2.1.51 0.0000000000000000000000000000000708 142.0
TH2_k127_5294061_7 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.000000000000000000106 94.0
TH2_k127_5300639_0 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.0 1442.0
TH2_k127_5300639_1 PFAM DNA methylase K07316 - 2.1.1.72 0.0 1332.0
TH2_k127_5300639_10 sequence-specific DNA binding - - - 0.00000000002717 66.0
TH2_k127_5300639_12 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000007932 53.0
TH2_k127_5300639_13 - - - - 0.0004874 46.0
TH2_k127_5300639_2 Z1 domain - - - 9.299e-229 729.0
TH2_k127_5300639_3 Protein of unknown function (DUF3037) - - - 0.0000000000000000000000000000000000000000000000000000000002088 212.0
TH2_k127_5300639_4 - - - - 0.00000000000000000000000000000000000000000000000000000000195 208.0
TH2_k127_5300639_5 HNH endonuclease K07454 - - 0.0000000000000000000000000000000000000000003405 173.0
TH2_k127_5300639_6 Trypsin - - - 0.0000000000000000000000000000000000000001701 154.0
TH2_k127_5300639_7 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000023 130.0
TH2_k127_5300639_8 restriction endodeoxyribonuclease activity - - - 0.000000000000000000000000000007972 134.0
TH2_k127_5300639_9 Cro/C1-type HTH DNA-binding domain K07729 - - 0.000000000000009395 75.0
TH2_k127_5321567_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000033 242.0
TH2_k127_5321567_1 - - - - 0.000000000000000000000000007609 119.0
TH2_k127_5321567_2 Las17-binding protein actin regulator - - - 0.00000001867 65.0
TH2_k127_5321567_3 - - - - 0.0000003299 59.0
TH2_k127_532483_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 6.982e-289 905.0
TH2_k127_532483_1 (ABC) transporter K15738 - - 9.456e-274 854.0
TH2_k127_532483_10 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K11206,K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 356.0
TH2_k127_532483_12 mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 310.0
TH2_k127_532483_13 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 297.0
TH2_k127_532483_14 lactoylglutathione lyase activity K08234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 292.0
TH2_k127_532483_15 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000001186 258.0
TH2_k127_532483_16 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001158 254.0
TH2_k127_532483_17 Serine hydrolase K07002,K19073 - 1.3.1.75 0.00000000000000000000000000000000000000000000000000000000000000000008105 235.0
TH2_k127_532483_18 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000004243 203.0
TH2_k127_532483_19 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000003458 189.0
TH2_k127_532483_2 belongs to the aldehyde dehydrogenase family K00128 GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 3.396e-228 723.0
TH2_k127_532483_20 acetyltransferase K18816 GO:0003674,GO:0003824,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0034069,GO:0042221,GO:0046677,GO:0047663,GO:0050896 2.3.1.82 0.000000000000000000000000000000000000000000000000006007 184.0
TH2_k127_532483_21 Histidine kinase K03406 - - 0.000000000000000000000000000000000000000000000001393 175.0
TH2_k127_532483_22 - - - - 0.00000000000000000000000000000000000000000000405 168.0
TH2_k127_532483_23 phosphorelay signal transduction system K02535 - 3.5.1.108 0.00000000000000000000000000000000002157 139.0
TH2_k127_532483_24 - - - - 0.000000000001633 72.0
TH2_k127_532483_3 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 2.586e-226 717.0
TH2_k127_532483_4 symporter activity K03307,K14387 - - 4.144e-223 700.0
TH2_k127_532483_5 saccharopine dehydrogenase activity K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 557.0
TH2_k127_532483_6 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 561.0
TH2_k127_532483_7 cyclic nucleotide binding K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 415.0
TH2_k127_532483_8 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 398.0
TH2_k127_532483_9 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 380.0
TH2_k127_5332236_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2239.0
TH2_k127_5332236_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.465e-296 916.0
TH2_k127_5332236_10 Transcription regulator of the Arc MetJ class - - - 0.0000000000000000004776 89.0
TH2_k127_5332236_12 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000002566 67.0
TH2_k127_5332236_2 ATPase activity - - - 6.288e-252 785.0
TH2_k127_5332236_3 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 419.0
TH2_k127_5332236_4 cysteine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006653 263.0
TH2_k127_5332236_5 Domain of unknown function (DUF5069) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006121 247.0
TH2_k127_5332236_6 - - - - 0.00000000000000000000000000000000000000000000000002828 184.0
TH2_k127_5332236_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000000146 168.0
TH2_k127_5332236_9 - - - - 0.0000000000000000000002066 108.0
TH2_k127_5338314_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 425.0
TH2_k127_5338314_1 coenzyme F420 binding K07226 - - 0.0000000000000000000000000000000000000000000000000000000000006253 213.0
TH2_k127_5341223_0 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 4.18e-270 837.0
TH2_k127_5341223_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000006407 212.0
TH2_k127_5346444_0 PFAM TonB-dependent Receptor Plug Domain K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 366.0
TH2_k127_5346444_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000005214 126.0
TH2_k127_5356700_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 8.501e-312 959.0
TH2_k127_5356700_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 511.0
TH2_k127_5356700_2 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 360.0
TH2_k127_5396142_0 ABC transporter K06020 - 3.6.3.25 0.0 1055.0
TH2_k127_5396142_1 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 383.0
TH2_k127_5396142_10 Protein of unknown function (DUF3568) - - - 0.0000000001997 68.0
TH2_k127_5396142_2 Alpha/beta hydrolase family K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 340.0
TH2_k127_5396142_3 thiolester hydrolase activity K06889,K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 329.0
TH2_k127_5396142_4 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 331.0
TH2_k127_5396142_5 epimerase K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 293.0
TH2_k127_5396142_6 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000001332 138.0
TH2_k127_5396142_8 - - - - 0.00000000000002869 74.0
TH2_k127_5410662_0 E1-E2 ATPase K01534 - 3.6.3.3,3.6.3.5 9.22e-251 788.0
TH2_k127_5415814_0 Domain of unknown function (DUF5069) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008497 247.0
TH2_k127_5415814_1 - - - - 0.000000000000000000007222 103.0
TH2_k127_5415814_4 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000001049 64.0
TH2_k127_5415814_5 Putative addiction module component - - - 0.0005285 46.0
TH2_k127_5436557_0 Protein export membrane protein K03296,K18138 - - 0.0 1447.0
TH2_k127_5436557_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000006207 126.0
TH2_k127_5438932_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.0 1152.0
TH2_k127_5438932_1 Hsp70 protein K04043,K04044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 597.0
TH2_k127_5438932_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000003843 227.0
TH2_k127_5438932_3 Iron-sulphur cluster assembly - - - 0.0000000000000000000000000000000006711 132.0
TH2_k127_5442211_0 transposase K07492 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000017 273.0
TH2_k127_5442211_1 alcohol dehydrogenase K13954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000001482 227.0
TH2_k127_5442211_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K00852,K01619 - 2.7.1.15,4.1.2.4 0.00000000000000000000000000000000000000000000004338 179.0
TH2_k127_5442211_3 Malate/L-lactate dehydrogenase - - - 0.000000000000000000095 93.0
TH2_k127_5448839_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 556.0
TH2_k127_5448839_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 530.0
TH2_k127_5448839_2 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 462.0
TH2_k127_5448839_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 401.0
TH2_k127_5448839_4 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000000000000000000000003812 225.0
TH2_k127_5448839_5 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000000001789 177.0
TH2_k127_5448839_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000001315 145.0
TH2_k127_5448839_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000021 99.0
TH2_k127_5448839_8 Ribosomal L32p protein family K02911 - - 0.000000000000001015 78.0
TH2_k127_5451101_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.52e-244 762.0
TH2_k127_5451101_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 520.0
TH2_k127_5451101_2 heat shock protein binding K05516,K05801,K18481 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007918 279.0
TH2_k127_5451101_3 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.0000000000000000000000000000000000000000009675 160.0
TH2_k127_5458174_0 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 505.0
TH2_k127_5458174_1 Evidence 2b Function of strongly homologous gene K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 460.0
TH2_k127_5458174_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 353.0
TH2_k127_5458174_3 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 306.0
TH2_k127_5458174_4 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000000000000000000000002171 225.0
TH2_k127_5464776_0 phosphorelay signal transduction system K07714 - - 2.085e-207 653.0
TH2_k127_5464776_1 photoreceptor activity K14978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 576.0
TH2_k127_5464776_2 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 360.0
TH2_k127_5464776_3 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000003336 207.0
TH2_k127_5464776_4 Chromate K07240 - - 0.0000000000000000000000000000000000000000006321 159.0
TH2_k127_5539422_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 442.0
TH2_k127_5539422_1 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 334.0
TH2_k127_5568763_0 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 333.0
TH2_k127_5568763_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 293.0
TH2_k127_5568763_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001292 274.0
TH2_k127_5568763_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000004459 199.0
TH2_k127_5568763_4 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.00000000000000000000000000000000000002387 148.0
TH2_k127_5568763_5 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000000000001273 140.0
TH2_k127_5568763_6 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000001203 118.0
TH2_k127_5572062_0 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 322.0
TH2_k127_5572062_1 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000002581 192.0
TH2_k127_5572062_2 cheY-homologous receiver domain - - - 0.000000000000000000000007733 106.0
TH2_k127_5572062_4 AAA domain - - - 0.00000000000000000000008322 99.0
TH2_k127_5572062_5 cheY-homologous receiver domain - - - 0.00000000000000000003759 95.0
TH2_k127_5572062_6 glucan 1,4-alpha-glucosidase activity K01178 - 3.2.1.3 0.00000000000000003459 85.0
TH2_k127_5583515_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 549.0
TH2_k127_5583515_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 378.0
TH2_k127_5583515_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002676 284.0
TH2_k127_5583515_3 protein homooligomerization - - - 0.0000000000000000000000000000000000000000000000000000000000000000008808 243.0
TH2_k127_5598098_0 NADPH-quinone reductase (modulator of drug activity B) K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000009095 187.0
TH2_k127_5604704_0 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 468.0
TH2_k127_5604704_1 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000007364 180.0
TH2_k127_5604704_2 - - - - 0.0000000001388 70.0
TH2_k127_5604704_3 sequence-specific DNA binding - - - 0.0005446 45.0
TH2_k127_5605799_0 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.933e-243 770.0
TH2_k127_5605799_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.978e-236 758.0
TH2_k127_5605799_2 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 546.0
TH2_k127_5605799_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 336.0
TH2_k127_5605799_4 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 322.0
TH2_k127_5605799_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000000001946 189.0
TH2_k127_5605799_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000001704 156.0
TH2_k127_5605799_7 Protein conserved in bacteria K09764 - - 0.00000000000000000000000000000000001116 137.0
TH2_k127_5606066_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1554.0
TH2_k127_5606066_1 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1298.0
TH2_k127_5606066_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000007991 214.0
TH2_k127_5606066_11 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000003821 192.0
TH2_k127_5606066_12 cell redox homeostasis - - - 0.0000000000000000000000000000000000000007906 154.0
TH2_k127_5606066_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000001642 143.0
TH2_k127_5606066_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0 1024.0
TH2_k127_5606066_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.11e-264 819.0
TH2_k127_5606066_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 1.915e-198 621.0
TH2_k127_5606066_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 529.0
TH2_k127_5606066_6 NADH-quinone oxidoreductase K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 381.0
TH2_k127_5606066_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 357.0
TH2_k127_5606066_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 308.0
TH2_k127_5606066_9 2 iron, 2 sulfur cluster binding K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 297.0
TH2_k127_5624127_0 xylulokinase activity K00854 - 2.7.1.17 5.504e-262 811.0
TH2_k127_5624127_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 366.0
TH2_k127_5624380_0 belongs to the thioredoxin family K02453,K07280,K20444,K20543 - - 0.0 1395.0
TH2_k127_5624380_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 330.0
TH2_k127_5624380_2 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843,K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007231 252.0
TH2_k127_566483_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 3.379e-215 676.0
TH2_k127_566483_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 468.0
TH2_k127_566483_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000004361 103.0
TH2_k127_5666058_0 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 301.0
TH2_k127_5666058_1 signal peptide protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000859 256.0
TH2_k127_5666058_2 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000000000000007515 110.0
TH2_k127_5687010_0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001371 251.0
TH2_k127_5687010_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000002422 226.0
TH2_k127_5687010_2 Rhodanese-like domain - - - 0.000000000000000000000000000000000000000000000000000000000002992 213.0
TH2_k127_5687010_3 - - - - 0.00000289 57.0
TH2_k127_5696587_0 Involved in the tonB-independent uptake of proteins K03641 - - 1.142e-194 612.0
TH2_k127_5696587_1 PAP2 superfamily K19302 - 3.6.1.27 0.000000000000000003112 91.0
TH2_k127_5716986_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.76e-318 986.0
TH2_k127_5716986_1 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 7.881e-267 830.0
TH2_k127_5716986_10 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 318.0
TH2_k127_5716986_11 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001264 246.0
TH2_k127_5716986_12 phosphonoacetaldehyde hydrolase activity K01091,K07025,K19270 - 3.1.3.18,3.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000424 249.0
TH2_k127_5716986_13 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001033 216.0
TH2_k127_5716986_14 - - - - 0.00000000000000000000000000000000000000000000000000000000001991 208.0
TH2_k127_5716986_16 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000002843 153.0
TH2_k127_5716986_17 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000005345 111.0
TH2_k127_5716986_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 606.0
TH2_k127_5716986_3 Male sterility protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 565.0
TH2_k127_5716986_4 Rieske (2fe-2S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 508.0
TH2_k127_5716986_5 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 465.0
TH2_k127_5716986_6 Formiminotransferase domain K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 445.0
TH2_k127_5716986_7 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 388.0
TH2_k127_5716986_8 uroporphyrinogen-III synthase activity K01719,K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 357.0
TH2_k127_5716986_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 353.0
TH2_k127_5719320_0 Bacterial regulatory protein, Fis family K10943 - - 7.747e-212 672.0
TH2_k127_5719320_1 phosphorelay sensor kinase activity K07708,K07710,K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 413.0
TH2_k127_5719320_2 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000000000000000000000000000000000000001509 238.0
TH2_k127_5719320_3 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000003009 201.0
TH2_k127_5719320_4 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000000000000000113 171.0
TH2_k127_5719320_5 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000000000009633 109.0
TH2_k127_5720406_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.672e-245 766.0
TH2_k127_5720406_1 Flavin containing amine oxidoreductase K06954 - - 2.278e-202 638.0
TH2_k127_5720406_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 608.0
TH2_k127_5720406_3 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 520.0
TH2_k127_5720406_4 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 343.0
TH2_k127_5720406_5 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 290.0
TH2_k127_5720406_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000216 282.0
TH2_k127_5720406_7 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000000000000001252 192.0
TH2_k127_5720406_8 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000001063 173.0
TH2_k127_5720406_9 Outer Membrane Lipoprotein K03098 - - 0.0000000000000000000000000000000000006202 140.0
TH2_k127_5723914_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 524.0
TH2_k127_5723914_1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000001527 168.0
TH2_k127_5734404_0 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 304.0
TH2_k127_5734404_1 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000001502 254.0
TH2_k127_5734404_2 Tat pathway signal sequence domain protein - - - 0.000000000001045 74.0
TH2_k127_5738570_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 407.0
TH2_k127_5746416_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 558.0
TH2_k127_5746416_1 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 418.0
TH2_k127_5746416_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009382 407.0
TH2_k127_5746416_3 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 372.0
TH2_k127_5746416_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 310.0
TH2_k127_5746416_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 296.0
TH2_k127_5746416_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000001299 245.0
TH2_k127_5746416_7 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000001333 147.0
TH2_k127_5746416_8 YacP-like NYN domain K06962 - - 0.000000000000000000000005104 108.0
TH2_k127_5766751_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 361.0
TH2_k127_5766751_3 PFAM Uncharacterised ACR, COG1259 K08999 - - 0.000000000000000000000000000000009957 130.0
TH2_k127_5771382_0 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 592.0
TH2_k127_5771382_1 RNA-3'-phosphate cyclase activity K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 347.0
TH2_k127_5771382_2 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002189 265.0
TH2_k127_5771382_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000004738 160.0
TH2_k127_5771382_4 Protein of unknown function (DUF1614) - - - 0.000000000000000000000000000000000000004636 149.0
TH2_k127_5771382_5 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000534 109.0
TH2_k127_5771382_6 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000006094 83.0
TH2_k127_5771382_7 Protein of unknown function (DUF1614) - - - 0.000003179 53.0
TH2_k127_5792904_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 8.26e-239 749.0
TH2_k127_5792904_1 Asparaginase K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009438 376.0
TH2_k127_5792904_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 309.0
TH2_k127_5792904_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000007093 210.0
TH2_k127_5792904_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000006105 179.0
TH2_k127_5792904_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000009133 175.0
TH2_k127_5792904_6 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000002132 117.0
TH2_k127_5795125_0 ATPase (AAA superfamily K06922 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 400.0
TH2_k127_5824201_0 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001097 280.0
TH2_k127_5824201_4 peptidase - - - 0.0000001105 55.0
TH2_k127_5835284_0 Kinase/pyrophosphorylase K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000002381 225.0
TH2_k127_5835284_1 beta-galactosidase activity - - - 0.000000001256 72.0
TH2_k127_5835284_2 PFAM aldo keto reductase - - - 0.000000004119 58.0
TH2_k127_5837111_0 methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 336.0
TH2_k127_5837111_4 Glutamine amidotransferase K01951 - 6.3.5.2 0.0000000000000000000000000000000000000001871 156.0
TH2_k127_5837111_6 - - - - 0.0000000000194 70.0
TH2_k127_5860391_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1044.0
TH2_k127_5860391_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 510.0
TH2_k127_5860391_2 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 505.0
TH2_k127_5860391_3 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 485.0
TH2_k127_5860391_4 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 388.0
TH2_k127_5860391_5 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000001092 244.0
TH2_k127_5865294_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases - - - 0.0 1293.0
TH2_k127_5876649_0 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 424.0
TH2_k127_5876649_1 Belongs to the pirin family K06911 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 299.0
TH2_k127_5876649_2 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000276 270.0
TH2_k127_5876649_3 Evidence 4 Homologs of previously reported genes of K15977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003102 253.0
TH2_k127_5876649_4 protein disulfide oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002053 254.0
TH2_k127_5876649_6 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000000000000000000000000000003627 138.0
TH2_k127_5888351_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.309e-225 702.0
TH2_k127_5888351_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 1.79e-213 672.0
TH2_k127_5888351_10 cell adhesion K02650 - - 0.000000000000000000000000000000000000000000000000000000000000001539 226.0
TH2_k127_5888351_12 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000007795 199.0
TH2_k127_5888351_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 1.778e-198 624.0
TH2_k127_5888351_3 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 560.0
TH2_k127_5888351_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 525.0
TH2_k127_5888351_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 482.0
TH2_k127_5888351_6 tRNA processing K04075,K14058,K21947 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.1.15,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 444.0
TH2_k127_5888351_8 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 354.0
TH2_k127_5888351_9 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 287.0
TH2_k127_5889634_0 cobalamin binding K21089,K21972,K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 327.0
TH2_k127_5889634_1 - - - - 0.00000000000000002749 90.0
TH2_k127_5895563_0 Probable transposase K07496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 343.0
TH2_k127_5895563_1 CGGC - - - 0.0000000000000000000000000000000000000000000000000000002713 197.0
TH2_k127_5895563_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000004701 171.0
TH2_k127_5895563_3 Staphylococcal nuclease homologues - - - 0.0000000000000000000000000000005246 128.0
TH2_k127_5895563_4 Staphylococcal nuclease homologues - - - 0.000004127 48.0
TH2_k127_5900432_0 SMART Chromosomal replication initiator DnaA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 319.0
TH2_k127_5900432_1 Phage integrase family - - - 0.00000000000000000000000000000000004937 135.0
TH2_k127_5900432_2 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000001973 91.0
TH2_k127_5900432_3 - - - - 0.0000006973 59.0
TH2_k127_5915791_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 576.0
TH2_k127_5915791_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 436.0
TH2_k127_5915791_10 Cupin domain - - - 0.0000000000000000009492 91.0
TH2_k127_5915791_11 nucleotide catabolic process K01181,K07004 - 3.2.1.8 0.0000000000000001878 80.0
TH2_k127_5915791_12 transposase activity K07483,K07497 - - 0.000000000000002114 77.0
TH2_k127_5915791_13 Bacterial Ig-like domain 2 - - - 0.000000000005325 80.0
TH2_k127_5915791_14 - - - - 0.0000000000364 67.0
TH2_k127_5915791_15 Integrase core domain - - - 0.0000000004131 65.0
TH2_k127_5915791_2 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000004015 267.0
TH2_k127_5915791_3 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000005383 232.0
TH2_k127_5915791_4 SnoaL-like domain K06893 - - 0.0000000000000000000000000000000000001721 146.0
TH2_k127_5915791_5 PFAM Alanine racemase, N-terminal - - - 0.00000000000000000000000000009909 117.0
TH2_k127_5915791_6 peptidase activity, acting on L-amino acid peptides K03385 - 1.7.2.2 0.0000000000000000000000007549 118.0
TH2_k127_5915791_7 Transposase - - - 0.00000000000000000000001184 102.0
TH2_k127_5915791_8 cellulose binding - - - 0.00000000000000000000003551 114.0
TH2_k127_5915791_9 cellulose binding - - - 0.0000000000000000000004711 113.0
TH2_k127_5926706_0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000005428 123.0
TH2_k127_5926706_1 copG family - - - 0.00000000000000000005936 93.0
TH2_k127_5935182_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 4.251e-197 622.0
TH2_k127_5935182_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 2.993e-196 618.0
TH2_k127_5935182_2 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 329.0
TH2_k127_5935182_3 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005067 271.0
TH2_k127_5935182_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002732 269.0
TH2_k127_5935182_5 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000001084 211.0
TH2_k127_5935182_6 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000000000000005661 186.0
TH2_k127_5935182_7 Putative regulatory protein - - - 0.0000000000000000000000000005915 117.0
TH2_k127_5935182_8 - - - - 0.000000000000000000000000004219 115.0
TH2_k127_594181_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.591e-221 691.0
TH2_k127_594181_1 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 394.0
TH2_k127_594181_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000001118 237.0
TH2_k127_594181_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000005689 135.0
TH2_k127_5955733_0 ATP-grasp domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003815 270.0
TH2_k127_5955733_1 belongs to the thioredoxin family K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000001597 246.0
TH2_k127_5955733_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000002596 204.0
TH2_k127_5955733_3 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000000000000000000000000611 186.0
TH2_k127_5955733_4 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000000000000002067 144.0
TH2_k127_5955733_5 Cytochrome c K00406 - - 0.00003745 46.0
TH2_k127_5970178_0 COGs COG0553 Superfamily II DNA RNA helicase SNF2 family - - - 2.503e-268 856.0
TH2_k127_5970178_1 Protein of unknown function (DUF1156) K07445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 411.0
TH2_k127_5970178_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000007449 135.0
TH2_k127_5970178_3 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000001481 125.0
TH2_k127_5971295_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 2.073e-200 629.0
TH2_k127_5971295_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007461 245.0
TH2_k127_5982011_0 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily K03321 - - 0.00000000000000000000000000002335 117.0
TH2_k127_5982011_1 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000000391 123.0
TH2_k127_5982011_2 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000004971 98.0
TH2_k127_5982011_3 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - 0.000000000000000006633 92.0
TH2_k127_5997683_0 belongs to the thioredoxin family K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000008776 231.0
TH2_k127_5997683_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000001336 179.0
TH2_k127_5997683_2 metallocarboxypeptidase activity - - - 0.000000000000000000000000000000000000000000000001472 183.0
TH2_k127_5997683_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000002815 132.0
TH2_k127_6015936_0 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000001644 84.0
TH2_k127_6015936_1 Parallel beta-helix repeats - - - 0.00005769 54.0
TH2_k127_6063977_1 ASPIC and UnbV - - - 0.000000000000000000000000009636 121.0
TH2_k127_6063977_2 pyrroloquinoline quinone binding - - - 0.00000002135 63.0
TH2_k127_6063977_3 S-layer homology domain K05349 - 3.2.1.21 0.000008086 60.0
TH2_k127_6063977_4 pyrroloquinoline quinone binding - - - 0.00001781 51.0
TH2_k127_6063977_5 PFAM glycoside hydrolase family 39 - - - 0.0001264 56.0
TH2_k127_6063977_6 Belongs to the glycosyl hydrolase 28 family - - - 0.0001665 56.0
TH2_k127_6063977_7 Protein of unknown function (DUF2569) - - - 0.0003014 47.0
TH2_k127_6076012_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.433e-199 632.0
TH2_k127_6076012_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000001984 163.0
TH2_k127_6076012_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000009561 53.0
TH2_k127_6091785_0 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601,K08965 - 4.1.1.39,5.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 333.0
TH2_k127_6091785_1 Histidine Phosphotransfer domain K05962 - 2.7.13.1 0.0000000000000000000000000000002458 136.0
TH2_k127_6091785_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000003604 128.0
TH2_k127_6091785_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000001156 84.0
TH2_k127_6097931_0 Protein of unknown function (DUF3604) - - - 3.028e-244 770.0
TH2_k127_6097931_1 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 551.0
TH2_k127_6097931_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 416.0
TH2_k127_6097931_3 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 329.0
TH2_k127_6097931_4 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008811 238.0
TH2_k127_6097931_5 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000007606 233.0
TH2_k127_6097931_6 HupE / UreJ protein - - - 0.00000000000000000000000000000000006988 146.0
TH2_k127_6097931_7 META domain K03929 - - 0.00000000000000000000000000001121 128.0
TH2_k127_6125519_0 TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type K00123 - 1.17.1.9 1.359e-249 801.0
TH2_k127_6125519_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335 - 1.6.5.3 3.198e-240 752.0
TH2_k127_6125519_10 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000005447 195.0
TH2_k127_6125519_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.000000000000000000000000000000000000000000000001285 177.0
TH2_k127_6125519_12 PFAM blue (type 1) copper domain protein K00368 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.00000000000000000000000000000000000000000001043 167.0
TH2_k127_6125519_13 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000002318 158.0
TH2_k127_6125519_15 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000001506 105.0
TH2_k127_6125519_16 Protein conserved in bacteria K03654 - 3.6.4.12 0.000000000000000000001178 108.0
TH2_k127_6125519_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 595.0
TH2_k127_6125519_4 formate transmembrane transporter activity K02598,K06212,K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 377.0
TH2_k127_6125519_5 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 359.0
TH2_k127_6125519_6 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 342.0
TH2_k127_6125519_7 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002047 285.0
TH2_k127_6125519_8 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K16370 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000008229 262.0
TH2_k127_6125519_9 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000003096 243.0
TH2_k127_6129673_0 ABC transporter substrate binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004505 280.0
TH2_k127_6129673_1 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000001159 224.0
TH2_k127_6129673_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000008918 135.0
TH2_k127_6129673_3 ABC transporter substrate binding protein K01989 - - 0.000000000000004282 81.0
TH2_k127_6129673_4 ABC transporter substrate binding protein K01989 - - 0.00000003294 55.0
TH2_k127_6141139_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 474.0
TH2_k127_6141139_1 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 333.0
TH2_k127_6141139_2 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000004348 211.0
TH2_k127_6150471_0 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000000002258 226.0
TH2_k127_6150471_1 aggregation factor core protein MAFp3, isoform C - - - 0.0000000000000000000000000000000000000000000000000000002365 220.0
TH2_k127_6150471_2 Putative cell wall binding repeat 2 - - - 0.00000000008112 68.0
TH2_k127_6155122_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0 1373.0
TH2_k127_6155122_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 604.0
TH2_k127_6155122_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 385.0
TH2_k127_6155122_3 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000000001412 138.0
TH2_k127_6155122_4 Protein of unknown function (DUF423) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000008107 143.0
TH2_k127_6155122_7 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000004904 66.0
TH2_k127_6161672_0 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 324.0
TH2_k127_6161672_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000004789 231.0
TH2_k127_6161672_2 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.000000001015 62.0
TH2_k127_6172430_0 Belongs to the N(4) N(6)-methyltransferase family K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886 344.0
TH2_k127_6172430_1 COG0419 ATPase involved in DNA repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 307.0
TH2_k127_6172430_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000002926 221.0
TH2_k127_6172430_3 rhs family - - - 0.000000000000000000000000000000006399 134.0
TH2_k127_6179848_0 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000006451 204.0
TH2_k127_6179848_2 - - - - 0.000000000000000000005363 100.0
TH2_k127_6184773_0 thiosulfate sulfurtransferase activity K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 477.0
TH2_k127_6184773_1 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 458.0
TH2_k127_6184773_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 456.0
TH2_k127_6184773_3 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 406.0
TH2_k127_6184773_4 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 306.0
TH2_k127_6184773_5 Small metal-binding protein - - - 0.000000000000000000001685 98.0
TH2_k127_6184773_6 cAMP biosynthetic process K03765,K07277 - - 0.000001992 60.0
TH2_k127_6184773_7 zinc metalloprotease K11749 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0009515 51.0
TH2_k127_6195656_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 1297.0
TH2_k127_6195656_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0 1194.0
TH2_k127_6195656_10 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 438.0
TH2_k127_6195656_11 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 434.0
TH2_k127_6195656_12 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 398.0
TH2_k127_6195656_13 membrane K08976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 367.0
TH2_k127_6195656_16 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002297 263.0
TH2_k127_6195656_19 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000003283 199.0
TH2_k127_6195656_2 Cytochrome c K00405 - - 5.411e-319 983.0
TH2_k127_6195656_3 aerobic electron transport chain K00425,K08738 - 1.10.3.14 1.479e-295 917.0
TH2_k127_6195656_4 Cytochrome c K00405 - - 3.149e-221 692.0
TH2_k127_6195656_5 Cytochrome c - - - 3.631e-207 646.0
TH2_k127_6195656_6 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 495.0
TH2_k127_6195656_7 rRNA (guanine-N2-)-methyltransferase activity K09846,K13604,K21460 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.210,2.1.1.304,2.1.1.333 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 482.0
TH2_k127_6195656_8 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 457.0
TH2_k127_6195656_9 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 460.0
TH2_k127_6205589_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.823e-268 831.0
TH2_k127_6205589_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000222 242.0
TH2_k127_6205589_2 ACT domain - - - 0.0000000000000000000000000000000000000000000000000000000000008005 212.0
TH2_k127_6210184_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 438.0
TH2_k127_6210184_1 C-terminal region of aryl-sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000002985 241.0
TH2_k127_6239960_0 alanine dehydrogenase activity K00259 GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009653,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030312,GO:0030435,GO:0032502,GO:0036293,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 569.0
TH2_k127_6239960_1 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 302.0
TH2_k127_6239960_2 - - - - 0.000000000000000000000000000000000000000000000000000009948 190.0
TH2_k127_6239960_3 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000001257 181.0
TH2_k127_6239960_4 - - - - 0.000000000000000000000000000000000000000000002097 168.0
TH2_k127_6239960_5 - - - - 0.00000000000000000000000000000000009564 143.0
TH2_k127_6239960_6 Belongs to the peptidase S16 family K06870 - - 0.0000000006707 70.0
TH2_k127_6239960_7 - - - - 0.0004185 44.0
TH2_k127_6249282_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 594.0
TH2_k127_6249282_1 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 482.0
TH2_k127_6249282_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 325.0
TH2_k127_6249282_3 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 321.0
TH2_k127_6249282_4 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000484 297.0
TH2_k127_6249282_5 bacterial-type flagellum organization K02279,K02386 - - 0.00000000000000000000000000000000000000000000000000001724 198.0
TH2_k127_6249282_6 GGDEF domain K13590 - 2.7.7.65 0.00000000000000000000000000004079 124.0
TH2_k127_6249282_7 bacterial-type flagellum organization K02398 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009892,GO:0010556,GO:0010605,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031324,GO:0031326,GO:0032268,GO:0032269,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.000000000000000000000005153 104.0
TH2_k127_6249282_8 Flagellar rod assembly protein muramidase FlgJ K02395,K08309 - - 0.000000000000002226 80.0
TH2_k127_6265053_0 Flagellar motor switch protein FliM K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 425.0
TH2_k127_6265053_1 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000001565 154.0
TH2_k127_6265053_2 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000000000000000000000000000000007802 143.0
TH2_k127_6265053_3 flagellar K02418,K02419 - - 0.000000000002195 73.0
TH2_k127_6265989_0 peroxiredoxin activity K01607,K04756 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000001573 215.0
TH2_k127_6265989_1 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000000000000000000008496 179.0
TH2_k127_6265989_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000001658 143.0
TH2_k127_6265989_3 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000006352 140.0
TH2_k127_6265989_4 - - - - 0.0000000000000000000000000004056 117.0
TH2_k127_6265989_5 - - - - 0.0000000000000000000000009152 110.0
TH2_k127_6265989_6 - - - - 0.0000000000004056 73.0
TH2_k127_6265989_7 Acetyltransferase (GNAT) domain K03824 - - 0.0002231 46.0
TH2_k127_6323303_0 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 355.0
TH2_k127_6323303_1 integral membrane protein - - - 0.000000000000000000000000000000002099 134.0
TH2_k127_6347962_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1171.0
TH2_k127_6347962_1 - K01992 - - 1.847e-233 737.0
TH2_k127_6347962_11 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000004166 241.0
TH2_k127_6347962_12 peptidoglycan binding K03642 - - 0.0000000000000000000000000000000000000000000000000000000002234 210.0
TH2_k127_6347962_14 - - - - 0.000000000000000000000000000000000000000001259 160.0
TH2_k127_6347962_15 DNA excision K02806 - - 0.0000000000000000000000000000000002059 135.0
TH2_k127_6347962_16 PIN domain - - - 0.000000000000000000000000000000001949 133.0
TH2_k127_6347962_17 cellulase activity - - - 0.0000000000000000000000000001709 131.0
TH2_k127_6347962_19 SpoVT / AbrB like domain - - - 0.00000000000002406 76.0
TH2_k127_6347962_21 - - - - 0.0008573 46.0
TH2_k127_6347962_3 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 531.0
TH2_k127_6347962_4 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 510.0
TH2_k127_6347962_5 ATPase activity K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 491.0
TH2_k127_6347962_6 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 476.0
TH2_k127_6347962_7 Replication initiation factor K07467 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 405.0
TH2_k127_6347962_8 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 381.0
TH2_k127_6347962_9 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 376.0
TH2_k127_6349655_0 Aminotransferase class-III - - - 1.37e-280 870.0
TH2_k127_6349655_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 317.0
TH2_k127_6375859_0 Evidence 2b Function of strongly homologous gene K01740,K03430,K05306,K09469 GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 462.0
TH2_k127_6375859_1 Belongs to the TPP enzyme family K09459 - 4.1.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 356.0
TH2_k127_6375859_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 277.0
TH2_k127_639465_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 580.0
TH2_k127_639465_1 Bacterial dnaA protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 389.0
TH2_k127_639465_2 ParB-like nuclease domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 359.0
TH2_k127_639465_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000001592 96.0
TH2_k127_6402181_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000009955 223.0
TH2_k127_6402181_1 Putative heavy-metal-binding - - - 0.000000000000000000000000000000000000000000000002545 174.0
TH2_k127_6402181_2 Nuclease (SNase domain protein) - - - 0.0000000000000000000000000000000000000000000001005 173.0
TH2_k127_6402181_3 Sulfatase - - - 0.0000000000000000000000000000000001085 135.0
TH2_k127_6402181_4 - - - - 0.0002881 46.0
TH2_k127_6422288_0 ATPase (AAA superfamily K06922 - - 0.0000000000000000000000000000000000000000000000000000000000000002146 233.0
TH2_k127_6422288_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 0.000000004873 57.0
TH2_k127_6435848_0 recombinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 468.0
TH2_k127_6435848_1 Resolvase domain - - - 0.00000000000003256 73.0
TH2_k127_6435848_2 recombinase activity - - - 0.0000000000001632 70.0
TH2_k127_6444312_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 314.0
TH2_k127_6444312_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000007953 235.0
TH2_k127_6457656_0 PFAM Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 465.0
TH2_k127_6457656_1 PFAM IstB-like ATP binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004014 274.0
TH2_k127_6457656_3 PIN domain - - - 0.00000000000000000000005095 103.0
TH2_k127_6457656_4 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.0000000000000001843 79.0
TH2_k127_6471779_0 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 324.0
TH2_k127_6471779_1 - - - - 0.000000000000000000000000000000000000000001658 158.0
TH2_k127_6471779_2 Pfam:DUF385 - - - 0.0000000000000000000000000000000008689 136.0
TH2_k127_6485373_0 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 384.0
TH2_k127_6485373_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 366.0
TH2_k127_6485373_2 phosphatidylcholine synthase activity K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 347.0
TH2_k127_6485373_3 dicarboxylic acid transport K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003288 267.0
TH2_k127_6485373_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003397 271.0
TH2_k127_6485373_5 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000003912 104.0
TH2_k127_6492197_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 9.127e-205 644.0
TH2_k127_6492197_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 410.0
TH2_k127_6492197_2 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 307.0
TH2_k127_6492197_3 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000007717 146.0
TH2_k127_6492197_4 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000004646 91.0
TH2_k127_6501775_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 3.78e-246 764.0
TH2_k127_6501775_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 290.0
TH2_k127_6501775_2 Glycoprotease family K14742 - - 0.000000000000000000000000000000000000000000000000000000000000000000135 239.0
TH2_k127_6501775_3 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000006094 173.0
TH2_k127_6532351_0 HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 603.0
TH2_k127_6532351_1 aldo-keto reductase (NADP) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 456.0
TH2_k127_6532351_2 - - - - 0.000000000001875 70.0
TH2_k127_6590297_0 - - - - 0.000000000000000000000007648 109.0
TH2_k127_6607552_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 470.0
TH2_k127_6607552_3 amino acid - - - 0.000000000000000000001884 93.0
TH2_k127_667213_0 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000000000000000009464 147.0
TH2_k127_667213_1 PFAM Uncharacterised ACR, COG1259 K08999 - - 0.0000000000000000000000000000000004233 132.0
TH2_k127_667213_2 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000003941 108.0
TH2_k127_667213_3 - - - - 0.0003507 45.0
TH2_k127_6685664_0 Anti-sigma-K factor rskA K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 309.0
TH2_k127_6685664_1 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003071 258.0
TH2_k127_6685664_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000003926 201.0
TH2_k127_6685664_3 transferase activity, transferring hexosyl groups - - - 0.0000000000000000000000000000000000000000000000000002485 191.0
TH2_k127_6685664_4 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000009111 143.0
TH2_k127_6685664_5 PFAM Integrase core domain - - - 0.00000000000002736 74.0
TH2_k127_6697244_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 591.0
TH2_k127_6697244_1 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 464.0
TH2_k127_6697244_2 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 448.0
TH2_k127_6697244_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000005139 209.0
TH2_k127_6697244_4 Putative Ig domain - - - 0.000000000000000000000000000000000000000002098 172.0
TH2_k127_6697244_5 transferase activity, transferring glycosyl groups - - - 0.000000000000001973 86.0
TH2_k127_6697244_6 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000003446 78.0
TH2_k127_6697244_7 DNA integration - - - 0.000000003675 61.0
TH2_k127_6697244_8 DNA integration - - - 0.000000007223 59.0
TH2_k127_6697244_9 PFAM nuclease (SNase domain protein) - - - 0.0000005201 52.0
TH2_k127_6700482_0 Type I restriction-modification system - - - 8.985e-220 685.0
TH2_k127_6700482_1 Abortive infection bacteriophage resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 362.0
TH2_k127_6700482_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03427 - 2.1.1.72 0.0000000000000000000000000000000000001686 143.0
TH2_k127_6700482_3 nuclease activity - - - 0.00000000000000000000000000000002111 130.0
TH2_k127_6705702_0 YaeQ - - - 0.0000000000000000000000000000000000000000000000000000000004428 204.0
TH2_k127_6705702_1 translation initiation factor activity K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000005511 191.0
TH2_k127_6705702_2 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0006972 44.0
TH2_k127_6707595_0 IMP dehydrogenase activity K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000001027 240.0
TH2_k127_6707595_1 Yip1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000007928 223.0
TH2_k127_6707595_2 Metallo-beta-lactamase superfamily K17725 - 1.13.11.18 0.00000000000000000000000000000000000001194 147.0
TH2_k127_6710137_0 Resolvase domain - - - 7.879e-252 789.0
TH2_k127_6710137_1 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000003251 171.0
TH2_k127_6710137_2 Family of unknown function (DUF5372) - - - 0.0000000000000000000001613 101.0
TH2_k127_6716032_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 387.0
TH2_k127_6723083_0 Evidence 2b Function of strongly homologous gene K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 467.0
TH2_k127_6723083_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K07052 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 426.0
TH2_k127_6723083_2 ADP-glyceromanno-heptose 6-epimerase activity K00311 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.5.5.1 0.0000000000000000000000000000000003545 134.0
TH2_k127_6723083_3 Histidine kinase-like ATPases - - - 0.0000000000000000000007676 111.0
TH2_k127_6751826_0 Conserved carboxylase domain K01960 - 6.4.1.1 0.0 1023.0
TH2_k127_6751826_1 Biotin carboxylase C-terminal domain K01959 - 6.4.1.1 4.76e-265 821.0
TH2_k127_6751826_10 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 379.0
TH2_k127_6751826_11 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 367.0
TH2_k127_6751826_12 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 362.0
TH2_k127_6751826_13 phosphate ion binding K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 353.0
TH2_k127_6751826_15 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 331.0
TH2_k127_6751826_16 thiolester hydrolase activity K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 319.0
TH2_k127_6751826_17 thioredoxin peroxidase activity K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 304.0
TH2_k127_6751826_18 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 298.0
TH2_k127_6751826_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00322,K00382 - 1.6.1.1,1.8.1.4 2.318e-227 711.0
TH2_k127_6751826_20 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000002454 221.0
TH2_k127_6751826_24 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000677 129.0
TH2_k127_6751826_25 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000002331 130.0
TH2_k127_6751826_27 - - - - 0.000000000000000002196 86.0
TH2_k127_6751826_3 mismatched DNA binding K03555 - - 1.805e-197 633.0
TH2_k127_6751826_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 603.0
TH2_k127_6751826_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 596.0
TH2_k127_6751826_6 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 536.0
TH2_k127_6751826_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 480.0
TH2_k127_6751826_8 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 426.0
TH2_k127_6751826_9 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 381.0
TH2_k127_6755196_0 PFAM Type II secretion system protein E K02283,K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 576.0
TH2_k127_6755196_1 PFAM Type II secretion system F K12510 - - 0.00000000000000000000000000000000000000000000000000000000001739 218.0
TH2_k127_6755196_2 - K02282 - - 0.00000000000000000000000000000001853 136.0
TH2_k127_6785673_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1208.0
TH2_k127_6785673_1 DHH family K07462 - - 3.457e-245 769.0
TH2_k127_6785673_2 hydrogen-translocating pyrophosphatase activity K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 415.0
TH2_k127_6785673_3 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000004391 129.0
TH2_k127_6801911_0 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001653 293.0
TH2_k127_6801911_1 ORF located using Blastx COG2801 - - - 0.000000000000000000000000000000000000000000000000000000001313 205.0
TH2_k127_6801911_3 Integrase core domain - - - 0.000000000000000000002311 94.0
TH2_k127_6801911_4 Iron-sulphur cluster assembly - - - 0.0000000000000000003193 86.0
TH2_k127_6801911_5 DDE superfamily endonuclease - - - 0.000000002856 58.0
TH2_k127_6809369_0 PFAM Type II secretion system protein E K02283,K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 569.0
TH2_k127_6809369_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 421.0
TH2_k127_6809369_2 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009826 267.0
TH2_k127_6809369_3 PFAM type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000004238 245.0
TH2_k127_6809369_4 Type II secretion system K12510 - - 0.000000000000000000000000000000000000000000000000000000000000003798 228.0
TH2_k127_6809369_5 AAA domain K02282 - - 0.000000000000000000000000000000000000000000000000000000108 210.0
TH2_k127_6809369_6 Acyltransferase family - - - 0.000000000000000000000000000000000000006356 157.0
TH2_k127_6809369_7 PFAM TadE family protein - - - 0.00000001996 57.0
TH2_k127_68165_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 617.0
TH2_k127_68165_1 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 326.0
TH2_k127_68165_2 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000001281 147.0
TH2_k127_68165_3 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000008901 98.0
TH2_k127_68165_4 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000003316 75.0
TH2_k127_68165_5 Domain of unknown function (DUF4386) - - - 0.0000000000001556 74.0
TH2_k127_68165_6 - - - - 0.0000000001467 68.0
TH2_k127_68165_7 Magnesium chelatase, subunit ChlI C-terminal K06400,K07391 - - 0.0000001901 57.0
TH2_k127_6836836_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.142e-249 774.0
TH2_k127_6836836_1 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 541.0
TH2_k127_6836836_2 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004028 258.0
TH2_k127_6836836_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000002253 220.0
TH2_k127_6836836_4 Membrane - - - 0.000000000000000000000000000001926 122.0
TH2_k127_6843240_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1230.0
TH2_k127_6843240_1 Heat shock 70 kDa protein K04043 - - 0.0 1116.0
TH2_k127_6843240_10 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001175 291.0
TH2_k127_6843240_11 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001872 248.0
TH2_k127_6843240_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000003125 222.0
TH2_k127_6843240_13 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000001362 224.0
TH2_k127_6843240_14 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000009725 209.0
TH2_k127_6843240_15 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000001543 208.0
TH2_k127_6843240_16 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000002295 168.0
TH2_k127_6843240_2 guanyl-nucleotide exchange factor activity - - - 6.312e-231 727.0
TH2_k127_6843240_3 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 415.0
TH2_k127_6843240_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 376.0
TH2_k127_6843240_5 phosphopentomutase activity K01839 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 368.0
TH2_k127_6843240_6 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 359.0
TH2_k127_6843240_7 deoxyribose-phosphate aldolase activity K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 347.0
TH2_k127_6843240_8 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 324.0
TH2_k127_6843240_9 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 316.0
TH2_k127_6864848_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1454.0
TH2_k127_6864848_1 Belongs to the citrate synthase family K01902,K15230,K15233 - 2.3.3.8,6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 500.0
TH2_k127_6864848_2 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 479.0
TH2_k127_6875422_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 4.874e-220 689.0
TH2_k127_6875422_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 496.0
TH2_k127_6875422_2 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 479.0
TH2_k127_6875422_3 LysR substrate binding domain K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 344.0
TH2_k127_6875422_4 Cytochrome bd-type quinol oxidase, subunit 2 K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 301.0
TH2_k127_6875422_5 cytochrome c nitrite reductase K15876 - - 0.000000000000000000000000000000000000000000000000000003707 194.0
TH2_k127_6875422_6 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.00000000000000000000000000000001485 127.0
TH2_k127_6875422_7 cheY-homologous receiver domain K03413 - - 0.000000000000000004335 89.0
TH2_k127_6875422_8 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.00000000001761 68.0
TH2_k127_6878533_0 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000004869 175.0
TH2_k127_6878533_1 CAAX amino terminal protease family - - - 0.00000000000000000000000000000000001266 149.0
TH2_k127_6878533_2 MarR family - - - 0.000000000000000000000000000000018 129.0
TH2_k127_6878533_3 Domain of unknown function (DUF4055) - - - 0.0001028 47.0
TH2_k127_6881732_0 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 3.986e-209 658.0
TH2_k127_6881732_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 409.0
TH2_k127_6881732_10 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000515 102.0
TH2_k127_6881732_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 293.0
TH2_k127_6881732_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001823 280.0
TH2_k127_6881732_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000121 278.0
TH2_k127_6881732_5 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
TH2_k127_6881732_6 metal cluster binding K06940 - - 0.00000000000000000000000000000000000000000000000000000007721 201.0
TH2_k127_6881732_8 regulation of translation K03530 - - 0.000000000000000000000000000000000000000000005326 165.0
TH2_k127_6881732_9 Mo-molybdopterin cofactor metabolic process K03636 - - 0.00000000000000000000000000000000000002192 145.0
TH2_k127_6919322_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 8.734e-286 900.0
TH2_k127_6919322_1 Phosphoglycerate kinase K00927 - 2.7.2.3 6.25e-228 710.0
TH2_k127_6919322_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 585.0
TH2_k127_6919322_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 529.0
TH2_k127_6919322_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 296.0
TH2_k127_6919322_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000000000000002162 166.0
TH2_k127_6919322_6 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000003163 153.0
TH2_k127_6919322_7 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000000000000001558 145.0
TH2_k127_6919322_9 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000001412 63.0
TH2_k127_695920_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.946e-238 742.0
TH2_k127_695920_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 566.0
TH2_k127_695920_2 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 402.0
TH2_k127_695920_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 392.0
TH2_k127_695920_4 peroxidase activity K09162 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042597,GO:0044464,GO:0050587,GO:0051213,GO:0055114 1.13.11.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 302.0
TH2_k127_695920_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01952 - 6.3.2.6,6.3.5.3 0.000000000000000000000000000000000000223 141.0
TH2_k127_6980074_0 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 7.149e-247 766.0
TH2_k127_6980074_1 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000007971 225.0
TH2_k127_6985596_0 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009798 466.0
TH2_k127_6985596_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 455.0
TH2_k127_6985596_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 312.0
TH2_k127_6985596_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002956 279.0
TH2_k127_6985596_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000000001719 235.0
TH2_k127_6985596_6 Cytochrome c - - - 0.000000000000000000000000000000000000000000002376 168.0
TH2_k127_6985596_7 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000006615 83.0
TH2_k127_6994770_0 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 334.0
TH2_k127_6994770_1 Leucine rich repeats (6 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002693 242.0
TH2_k127_6994770_2 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000002235 207.0
TH2_k127_7006591_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00982,K00990 - 2.7.7.42,2.7.7.59,2.7.7.89 0.0 1259.0
TH2_k127_7006591_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 8.391e-303 929.0
TH2_k127_7006591_10 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000002971 240.0
TH2_k127_7006591_11 Nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000001491 204.0
TH2_k127_7006591_12 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000000000000005504 185.0
TH2_k127_7006591_13 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000001115 168.0
TH2_k127_7006591_2 Nitrite and sulphite reductase 4Fe-4S domain K00366,K00392 - 1.7.7.1,1.8.7.1 1.54e-260 811.0
TH2_k127_7006591_3 ANTAR - - - 5.433e-222 693.0
TH2_k127_7006591_4 Secretin and TonB N terminus short domain K02666 - - 1.126e-219 704.0
TH2_k127_7006591_5 Ammonium Transporter Family K03320 - - 1.307e-208 658.0
TH2_k127_7006591_6 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 2.791e-199 640.0
TH2_k127_7006591_7 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 613.0
TH2_k127_7006591_8 formate transmembrane transporter activity K02598,K06212,K21993 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 465.0
TH2_k127_7006591_9 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 455.0
TH2_k127_7026262_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1123.0
TH2_k127_7026262_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 4.497e-245 762.0
TH2_k127_7026262_10 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 300.0
TH2_k127_7026262_11 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001301 252.0
TH2_k127_7026262_12 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000007273 214.0
TH2_k127_7026262_2 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 4.859e-212 672.0
TH2_k127_7026262_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.041e-203 643.0
TH2_k127_7026262_4 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 541.0
TH2_k127_7026262_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 452.0
TH2_k127_7026262_6 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 379.0
TH2_k127_7026262_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 359.0
TH2_k127_7026262_8 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 307.0
TH2_k127_7026262_9 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 290.0
TH2_k127_704206_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0 1367.0
TH2_k127_704206_1 Lysine-2,3-aminomutase K01843 - 5.4.3.2 4.159e-218 681.0
TH2_k127_704206_10 - - - - 0.00004278 53.0
TH2_k127_704206_2 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 1.146e-203 643.0
TH2_k127_704206_3 - - - - 6.935e-198 629.0
TH2_k127_704206_4 Associated with various cellular activities K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 463.0
TH2_k127_704206_5 Uncharacterised conserved protein (DUF2156) K01163,K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009618 431.0
TH2_k127_704206_6 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000512 153.0
TH2_k127_704206_7 glutathione transferase activity K00799 - 2.5.1.18 0.000000000000000000000000000000000001112 139.0
TH2_k127_704206_9 DUF167 K09131 - - 0.0000000000000000000537 93.0
TH2_k127_7042384_0 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 299.0
TH2_k127_7042384_1 HlyD family secretion protein K03585 - - 0.000000000000005105 81.0
TH2_k127_7045862_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K19585 - - 0.0 1117.0
TH2_k127_7057575_0 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000000000000000000000000000000000000006561 199.0
TH2_k127_7060671_0 NeuB family K01654 - 2.5.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 323.0
TH2_k127_7060671_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000001908 168.0
TH2_k127_7081230_0 Sulfatase K01130 - 3.1.6.1 0.0 1204.0
TH2_k127_7081230_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 455.0
TH2_k127_7081230_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 461.0
TH2_k127_7081230_3 PFAM Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 399.0
TH2_k127_7081230_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006294 291.0
TH2_k127_7081230_5 PFAM Ion transport K08714 - - 0.000000000000000000000000000000000000000000000000000000000000003738 226.0
TH2_k127_7081230_6 cellulose binding - - - 0.0000000000000000000000000000000000000000000000003963 188.0
TH2_k127_7081230_7 pyrroloquinoline quinone binding K00117 - 1.1.5.2 0.000000000000000000009169 107.0
TH2_k127_7085182_0 periplasmic K07218 - - 0.000000005035 69.0
TH2_k127_7085182_1 beta-galactosidase K01190 - 3.2.1.23 0.0005773 53.0
TH2_k127_7090708_0 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 398.0
TH2_k127_7090708_1 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009311 246.0
TH2_k127_7090708_3 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000002767 188.0
TH2_k127_7090708_5 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000000000003698 128.0
TH2_k127_7111527_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000001464 143.0
TH2_k127_7111527_1 - - - - 0.0000000000000000001363 94.0
TH2_k127_7118822_0 siderophore transport K02014 - - 0.0 1260.0
TH2_k127_7118822_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000167 203.0
TH2_k127_7118822_3 Histidine kinase - - - 0.00000525 50.0
TH2_k127_7126932_0 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000002317 266.0
TH2_k127_7129150_0 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 565.0
TH2_k127_7129150_1 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 560.0
TH2_k127_7129150_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 476.0
TH2_k127_7129150_3 photosynthesis K02453,K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 358.0
TH2_k127_7147119_0 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 371.0
TH2_k127_7147119_2 phosphatase - - - 0.0000000000000000000000000000000000004575 144.0
TH2_k127_7176658_0 Recombinase - - - 5.459e-259 810.0
TH2_k127_7176658_1 recombinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 464.0
TH2_k127_7176658_2 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 372.0
TH2_k127_7176658_3 DNA invertase Pin - - - 0.00000000000000000000000000000000000000000000000000000000000004359 218.0
TH2_k127_7176658_4 PFAM Transposase IS200 like K07491 - - 0.000007146 49.0
TH2_k127_7185159_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 321.0
TH2_k127_7185159_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001218 234.0
TH2_k127_7185159_2 Histidine phosphatase superfamily (branch 1) K08296 - - 0.000000000000000000000000000000005181 133.0
TH2_k127_7186337_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 2.154e-195 619.0
TH2_k127_7186337_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000004825 229.0
TH2_k127_7186969_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 1.184e-208 655.0
TH2_k127_7186969_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 353.0
TH2_k127_7186969_2 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000165 103.0
TH2_k127_7186969_4 cellulose binding - - - 0.0000000000000000001348 89.0
TH2_k127_7201643_0 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 302.0
TH2_k127_7201643_1 PIN domain - - - 0.000000000000000000000000000000000000000000000000002547 184.0
TH2_k127_7201643_2 Ribbon-helix-helix domain - - - 0.000003549 49.0
TH2_k127_720439_0 mRNA catabolic process K06950 - - 0.0000000000000000000000000000002968 130.0
TH2_k127_720439_2 - - - - 0.000000001091 66.0
TH2_k127_7215034_0 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 443.0
TH2_k127_7215034_1 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001044 251.0
TH2_k127_7215034_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.00000000000000000000000000000000000000000000009612 170.0
TH2_k127_7215034_3 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000003622 87.0
TH2_k127_7223357_0 - - - - 0.000000000000000000000000000000000000000000000000000001426 208.0
TH2_k127_7223357_1 Glycosyltransferase like family 2 - - - 0.00000000000001768 84.0
TH2_k127_7227982_0 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 383.0
TH2_k127_7227982_1 - - - - 0.00000001793 58.0
TH2_k127_7248820_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 429.0
TH2_k127_7248820_1 amine dehydrogenase activity K12287 - - 0.000000000244 70.0
TH2_k127_7269293_0 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 484.0
TH2_k127_7269293_1 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000008317 211.0
TH2_k127_7269293_2 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000007267 158.0
TH2_k127_7272554_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 469.0
TH2_k127_7272554_1 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 456.0
TH2_k127_7272554_2 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 451.0
TH2_k127_7272554_3 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 347.0
TH2_k127_7272554_4 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 306.0
TH2_k127_7272554_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000001945 256.0
TH2_k127_7276883_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 446.0
TH2_k127_7276883_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000005963 108.0
TH2_k127_7288291_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 5.095e-205 644.0
TH2_k127_7288291_1 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 490.0
TH2_k127_7288291_10 chemotaxis K02659,K03408,K03415,K11524 - - 0.0000000000000000000000000005079 119.0
TH2_k127_7288291_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K05553 - - 0.000000000000000000000000001791 122.0
TH2_k127_7288291_2 Signal transducing histidine kinase, homodimeric domain K02487,K03407,K06596 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009116 504.0
TH2_k127_7288291_3 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 459.0
TH2_k127_7288291_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 453.0
TH2_k127_7288291_5 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 419.0
TH2_k127_7288291_6 nuclear chromosome segregation K02666,K03497,K19622 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004063 289.0
TH2_k127_7288291_8 PFAM metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000006978 151.0
TH2_k127_7288291_9 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.000000000000000000000000000000002163 130.0
TH2_k127_7297764_0 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 501.0
TH2_k127_7297764_1 S-Adenosylmethionine synthetase K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 361.0
TH2_k127_7297764_2 - - - - 0.00000000000000000000000000000000000004677 147.0
TH2_k127_7297764_3 Acyl-ACP thioesterase - - - 0.000000000000000000000000000007627 123.0
TH2_k127_7298159_0 Pup-ligase protein K20814 - 3.5.1.119 1.011e-277 859.0
TH2_k127_7298159_1 Proteasomal ATPase OB/ID domain K13527 - - 8.552e-276 857.0
TH2_k127_7298159_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K08070 - 1.3.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 527.0
TH2_k127_7298159_3 Proteasome subunit K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 422.0
TH2_k127_7298159_4 Proteasome subunit K03432 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 347.0
TH2_k127_7298159_5 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000065 211.0
TH2_k127_7298159_6 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000001295 164.0
TH2_k127_7298159_7 May function as a protein modifier covalently attached to lysine residues of substrate proteins. This may serve to target the modified proteins for degradation by proteasomes - - - 0.0000000000000000000002022 102.0
TH2_k127_731547_0 Asparagine synthase K01953 - 6.3.5.4 1.053e-273 855.0
TH2_k127_7321474_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 341.0
TH2_k127_7321474_1 Transposase and inactivated derivatives K07498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 297.0
TH2_k127_7321474_2 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0000000000000000000000000000003524 123.0
TH2_k127_7339968_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K12452 - 1.17.1.1 9.914e-210 659.0
TH2_k127_7339968_1 Elongator protein 3, MiaB family, Radical SAM K04034 - 1.21.98.3 5.188e-202 642.0
TH2_k127_7339968_10 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000001189 212.0
TH2_k127_7339968_11 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed - - - 0.0000000000000000000000000000000000000000000000000000001518 202.0
TH2_k127_7339968_12 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K03273,K15669 - 2.7.7.71,3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000003081 202.0
TH2_k127_7339968_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 567.0
TH2_k127_7339968_3 GHMP kinase K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 543.0
TH2_k127_7339968_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006596 470.0
TH2_k127_7339968_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 357.0
TH2_k127_7339968_6 Transketolase, pyrimidine binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 328.0
TH2_k127_7339968_7 SMART Metal-dependent phosphohydrolase, HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 315.0
TH2_k127_7339968_8 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001559 247.0
TH2_k127_7339968_9 GDP-L-fucose synthetase. Source PGD - - - 0.0000000000000000000000000000000000000000000000000000000000000009113 231.0
TH2_k127_7343123_0 RNA-binding PUA-like domain of methyltransferase RsmF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 441.0
TH2_k127_7343123_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 318.0
TH2_k127_7343123_2 TIGRFAM metal dependent phophohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 297.0
TH2_k127_7343123_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000408 63.0
TH2_k127_7343772_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 572.0
TH2_k127_7343772_2 - - - - 0.00000000000000000000000000000000000000000000000001518 185.0
TH2_k127_7343772_4 Major facilitator superfamily K06902 - - 0.00001148 48.0
TH2_k127_7366621_0 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001399 290.0
TH2_k127_7366621_1 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000000000007121 185.0
TH2_k127_7366621_2 - - - - 0.000000000000000001626 85.0
TH2_k127_7371937_0 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002786 285.0
TH2_k127_7371937_1 ABC transporter related K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000001143 206.0
TH2_k127_7371937_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000000001952 139.0
TH2_k127_7371937_3 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000001998 139.0
TH2_k127_7371937_4 Ribbon-helix-helix protein, copG family - - - 0.000000000000000000000001453 106.0
TH2_k127_7371937_5 Putative addiction module component - - - 0.0000000000000000000006807 98.0
TH2_k127_7371937_6 PIN domain protein - - - 0.00000000000002491 74.0
TH2_k127_7371937_7 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000001163 69.0
TH2_k127_7371937_8 PIN domain - - - 0.0000000489 56.0
TH2_k127_7395774_0 Aminotransferase class I and II K10206 - 2.6.1.83 3.772e-247 764.0
TH2_k127_7395774_1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002586 254.0
TH2_k127_7395774_2 glutamine amidotransferase K01951 - 6.3.5.2 0.00000000000000000000000000000001359 132.0
TH2_k127_7407834_0 Polysaccharide biosynthesis protein K01709 - 4.2.1.45 1.274e-201 632.0
TH2_k127_7407834_1 Nucleotidyl transferase K00978,K15669 - 2.7.7.33,2.7.7.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 478.0
TH2_k127_7407834_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 358.0
TH2_k127_7407834_3 glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 308.0
TH2_k127_7407834_4 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000002694 145.0
TH2_k127_7407834_5 Polysaccharide deacetylase - - - 0.00000000000000000000000004965 117.0
TH2_k127_7407834_6 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000007519 117.0
TH2_k127_7407834_7 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000007763 95.0
TH2_k127_7407834_8 Acetyltransferase (GNAT) domain K05363,K11693,K11694,K11695,K12554,K18354 - 2.3.2.10,2.3.2.16,2.3.2.17,2.3.2.18 0.00000003465 61.0
TH2_k127_7425592_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 391.0
TH2_k127_7425592_1 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000002087 168.0
TH2_k127_7429645_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 494.0
TH2_k127_7429645_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001041 229.0
TH2_k127_7436223_0 nitric oxide reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 336.0
TH2_k127_7436223_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000001192 176.0
TH2_k127_7436223_2 DsrE/DsrF-like family - - - 0.000000000000006146 78.0
TH2_k127_7436223_3 Thioesterase superfamily - - - 0.0000001319 53.0
TH2_k127_7442714_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 546.0
TH2_k127_7442714_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 297.0
TH2_k127_7442714_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000000000000000002404 236.0
TH2_k127_74449_0 TIGRFAM outer membrane adhesin like proteiin - - - 0.000000000000000000000000000000000000024 168.0
TH2_k127_74449_1 domain, Protein K01181 - 3.2.1.8 0.000000000000000000000000000001811 142.0
TH2_k127_74449_2 Parallel beta-helix repeats - - - 0.00000000000000000000000000006445 137.0
TH2_k127_74449_3 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000002912 79.0
TH2_k127_7447765_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 324.0
TH2_k127_7447765_1 Thioesterase K07107 - - 0.0000000000000000000000000000000000000000000003868 171.0
TH2_k127_7447765_2 aminopeptidase activity K07004 - - 0.0000000000003999 71.0
TH2_k127_7466624_0 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 359.0
TH2_k127_7466624_1 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000002967 235.0
TH2_k127_7476622_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000006622 212.0
TH2_k127_7476622_1 methyltransferase activity - - - 0.0000000000000000000000000003712 117.0
TH2_k127_7476622_2 Beta-lactamase - - - 0.00000000000006101 76.0
TH2_k127_7484476_0 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000002598 217.0
TH2_k127_7484476_1 IMP dehydrogenase activity K07182 - - 0.00000000000000000000000000000000000000000000000000000003262 199.0
TH2_k127_7484476_2 silver ion transport K15726 - - 0.00000000000000000000000000000000000000000000000008162 180.0
TH2_k127_7484476_4 IMP dehydrogenase activity K07182 - - 0.000000000000000000000000000000002336 134.0
TH2_k127_7492978_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1369.0
TH2_k127_7492978_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.339e-229 723.0
TH2_k127_7492978_2 Alpha/beta hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 312.0
TH2_k127_7492978_3 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001001 288.0
TH2_k127_7492978_6 sequence-specific DNA binding - - - 0.0000000000000000000000000000002329 124.0
TH2_k127_7516784_0 Proton-conducting membrane transporter K12137 - - 6.557e-319 987.0
TH2_k127_7516784_1 phosphorelay signal transduction system K02481 - - 2.887e-231 721.0
TH2_k127_7516784_10 Hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 338.0
TH2_k127_7516784_11 Product type r regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 284.0
TH2_k127_7516784_12 Cytochrome c K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001906 255.0
TH2_k127_7516784_13 Transcriptional regulator, Crp Fnr family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003618 255.0
TH2_k127_7516784_14 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001328 248.0
TH2_k127_7516784_15 OsmC-like protein K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000002607 233.0
TH2_k127_7516784_16 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.000000000000000000000000000000000000000000000000000000000000006994 216.0
TH2_k127_7516784_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000717 217.0
TH2_k127_7516784_18 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000491 168.0
TH2_k127_7516784_19 Sulphur transport K07112 - - 0.00000000000000000000000000000000002163 141.0
TH2_k127_7516784_2 Proton-conducting membrane transporter K12141 - - 5.73e-204 646.0
TH2_k127_7516784_22 Cytochrome c K12263 - - 0.00000000000000000000002136 103.0
TH2_k127_7516784_3 Cytochrome c K12263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 579.0
TH2_k127_7516784_4 phosphorelay sensor kinase activity K02668,K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 582.0
TH2_k127_7516784_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 578.0
TH2_k127_7516784_6 polyphosphate kinase activity K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 566.0
TH2_k127_7516784_7 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 462.0
TH2_k127_7516784_8 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 390.0
TH2_k127_7516784_9 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 347.0
TH2_k127_763723_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 588.0
TH2_k127_763723_1 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 571.0
TH2_k127_763723_2 photosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 310.0
TH2_k127_763723_4 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000002164 191.0
TH2_k127_763723_5 GGDEF domain - - - 0.0000000000000000000000000000000000000000000002281 169.0
TH2_k127_763723_7 glycerophosphoryl diester phosphodiesterase K01113,K01126 - 3.1.3.1,3.1.4.46 0.000000000000001192 80.0
TH2_k127_7655067_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02487,K03407,K06596 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0019904,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145 2.7.13.3 6.099e-251 784.0
TH2_k127_7655067_1 PFAM chemotaxis K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 488.0
TH2_k127_7655067_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004169 241.0
TH2_k127_7660161_0 AAA ATPase domain - - - 4.182e-223 739.0
TH2_k127_7660161_1 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000001224 107.0
TH2_k127_7660161_2 Fibronectin type 3 domain - - - 0.00000000003448 74.0
TH2_k127_7670124_0 PFAM Sulfatase K01130 - 3.1.6.1 8.53e-312 969.0
TH2_k127_7670124_1 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.00000000000000000000000000000000000007253 144.0
TH2_k127_7685331_0 transposition K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003717 279.0
TH2_k127_7685331_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000001605 119.0
TH2_k127_7685331_2 transposase activity - - - 0.000119 49.0
TH2_k127_7697325_0 Aminotransferase class I and II K14261 - - 1.155e-224 698.0
TH2_k127_7697325_1 Homoserine dehydrogenase K00003 - 1.1.1.3 1.192e-223 700.0
TH2_k127_7697325_2 ACT domain K00928 - 2.7.2.4 1.707e-196 621.0
TH2_k127_7697325_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 600.0
TH2_k127_7697325_4 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 468.0
TH2_k127_7770125_0 glycosyl transferase family 2 K20444 - - 4.947e-282 884.0
TH2_k127_7770125_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 380.0
TH2_k127_7770125_2 Beta-galactosidase - - - 0.000000000000000000000000000000000000000003698 166.0
TH2_k127_7770125_3 cephalosporin hydroxylase K01190,K12308 - 3.2.1.23 0.0000000000000000000000003102 117.0
TH2_k127_779957_0 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 430.0
TH2_k127_7813266_0 Multicopper oxidase - - - 0.0 1824.0
TH2_k127_7813266_1 Cytochrome D1 heme domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 573.0
TH2_k127_7813266_2 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001867 291.0
TH2_k127_7813266_3 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000001822 184.0
TH2_k127_7813266_4 peptidyl-prolyl cis-trans isomerase activity K03769,K07533 - 5.2.1.8 0.0000000000000000000000000000000000000000000000278 183.0
TH2_k127_7813266_5 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000001088 176.0
TH2_k127_7813266_6 Transglycosylase K08309 - - 0.0000000000000000000000000000000000001684 151.0
TH2_k127_7820014_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 2.281e-256 791.0
TH2_k127_7820014_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 580.0
TH2_k127_7820014_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 443.0
TH2_k127_7820014_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 411.0
TH2_k127_7820014_4 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000002826 173.0
TH2_k127_7827670_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 4.182e-226 717.0
TH2_k127_7827670_1 Protein involved in outer membrane biogenesis K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 591.0
TH2_k127_7827670_10 Resolvase - - - 0.00001321 49.0
TH2_k127_7827670_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 449.0
TH2_k127_7827670_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 361.0
TH2_k127_7827670_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000000000001339 237.0
TH2_k127_7827670_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000002171 161.0
TH2_k127_7827670_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000001526 143.0
TH2_k127_7827670_8 Leucine rich repeat N-terminal domain - - - 0.0000000000001018 74.0
TH2_k127_7831091_0 thiamine transport K02011 - - 2.417e-230 726.0
TH2_k127_7831091_1 Tetratricopeptide repeat - - - 2.674e-209 658.0
TH2_k127_7831091_10 spore germination - - - 0.000000000000000000000000000000000000000000003086 168.0
TH2_k127_7831091_11 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0004032 51.0
TH2_k127_7831091_2 iron ion homeostasis K02012 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 523.0
TH2_k127_7831091_3 ATPase activity K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 520.0
TH2_k127_7831091_4 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299,K03281 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 482.0
TH2_k127_7831091_5 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 419.0
TH2_k127_7831091_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 385.0
TH2_k127_7831091_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 302.0
TH2_k127_7831091_9 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004 271.0
TH2_k127_7835959_0 lyase activity K01387,K03301 - 3.4.24.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 317.0
TH2_k127_7835959_1 HEAT repeat - - - 0.000005065 59.0
TH2_k127_7842732_0 Belongs to the RtcB family K14415 - 6.5.1.3 1.779e-228 715.0
TH2_k127_7842732_1 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 426.0
TH2_k127_7842732_2 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 379.0
TH2_k127_7842732_3 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000006782 155.0
TH2_k127_7842732_4 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0002839 44.0
TH2_k127_7843784_0 Response regulator, receiver K20973 - 2.7.13.3 5.047e-223 716.0
TH2_k127_7843784_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 504.0
TH2_k127_7843784_11 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000001005 199.0
TH2_k127_7843784_12 - K14588 - - 0.000000000000000000000000000000000000000005779 158.0
TH2_k127_7843784_14 PFAM Hpt domain protein - - - 0.00000000000000000000009225 105.0
TH2_k127_7843784_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 466.0
TH2_k127_7843784_3 Squalene/phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 448.0
TH2_k127_7843784_4 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 435.0
TH2_k127_7843784_5 transmembrane transport K02532,K05820,K08167,K08218,K08369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 445.0
TH2_k127_7843784_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 315.0
TH2_k127_7843784_7 response regulator, receiver K03413,K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 307.0
TH2_k127_7843784_8 Belongs to the glutathione peroxidase family K00432,K20207 - 1.11.1.22,1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 295.0
TH2_k127_7843784_9 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001853 266.0
TH2_k127_7843942_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 4.852e-204 652.0
TH2_k127_7843942_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 598.0
TH2_k127_7843942_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 396.0
TH2_k127_7843942_3 acr, cog1565 K00412,K00971,K02275,K02389,K03177,K17624 - 1.9.3.1,2.7.7.13,3.2.1.97,5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 377.0
TH2_k127_7843942_4 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 349.0
TH2_k127_7843942_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004191 268.0
TH2_k127_7843942_6 PAP2 superfamily K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000002074 175.0
TH2_k127_7843942_7 lipid-A-disaccharide synthase activity - - - 0.00000000000000000000000000000000000000001087 155.0
TH2_k127_7843942_8 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000001363 139.0
TH2_k127_7846176_0 Uncharacterized ACR, YdiU/UPF0061 family K08997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 554.0
TH2_k127_7846176_1 NADH-quinone oxidoreductase K00341,K05577 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000003091 216.0
TH2_k127_7846176_2 Uncharacterized conserved protein (DUF2294) - - - 0.000000000000000000000000000000000000000000000008899 174.0
TH2_k127_787697_0 Phosphate acyltransferases K01897,K05939 - 2.3.1.40,6.2.1.20,6.2.1.3 3.243e-315 981.0
TH2_k127_787697_1 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 559.0
TH2_k127_787697_2 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 531.0
TH2_k127_787697_3 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 390.0
TH2_k127_787697_4 COG3000 Sterol desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008417 232.0
TH2_k127_787697_5 - - - - 0.00000000000000002055 86.0
TH2_k127_787697_6 DNA-templated transcription, initiation K03088 - - 0.0000002326 55.0
TH2_k127_787697_7 - - - - 0.00002568 49.0
TH2_k127_7878414_0 Polynucleotide adenylyltransferase K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 358.0
TH2_k127_7878414_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009779 355.0
TH2_k127_7879131_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 8.76e-264 821.0
TH2_k127_7879131_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 8.406e-211 659.0
TH2_k127_7879131_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 565.0
TH2_k127_7879131_3 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000000006207 214.0
TH2_k127_7879131_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000003684 115.0
TH2_k127_7879131_5 Bacterial protein of unknown function (DUF948) - - - 0.0002274 44.0
TH2_k127_787971_0 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003546 267.0
TH2_k127_787971_1 self proteolysis - - - 0.00001114 59.0
TH2_k127_7885935_0 ABC transporter K06020 - 3.6.3.25 0.0 1049.0
TH2_k127_7885935_1 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 384.0
TH2_k127_7885935_2 epimerase K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002607 281.0
TH2_k127_7885935_4 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.00003087 48.0
TH2_k127_7909570_0 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 590.0
TH2_k127_7909570_1 pseudouridine synthase activity K06176 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 488.0
TH2_k127_7909570_2 dimethylargininase activity K00819 GO:0003674,GO:0003824,GO:0016403,GO:0016787,GO:0016810,GO:0016813 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 419.0
TH2_k127_7909570_3 deoxyhypusine monooxygenase activity K02632 - 4.4.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000001878 244.0
TH2_k127_7909570_4 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000002302 208.0
TH2_k127_7911555_0 Protein of unknown function (DUF3604) - - - 1.575e-219 683.0
TH2_k127_7911555_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 396.0
TH2_k127_7911555_2 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000002 213.0
TH2_k127_7911555_3 - - - - 0.00000000000000000000000000000000000000000000000000000005561 200.0
TH2_k127_7911555_4 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000000000000000001333 165.0
TH2_k127_7911555_5 Flavocytochrome c sulphide dehydrogenase, flavin-binding - - - 0.0003855 43.0
TH2_k127_7913547_0 Glycogen debranching enzyme - - - 0.0 1172.0
TH2_k127_7922415_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.858e-311 962.0
TH2_k127_7922415_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.049e-278 919.0
TH2_k127_7922415_10 Acyl-homoserine-lactone synthase K13060,K13061,K18096,K20248,K20249,K20250 - 2.3.1.184,2.3.1.228,2.3.1.229 0.00000000000000000000000000000000000000000000000003076 188.0
TH2_k127_7922415_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000006304 203.0
TH2_k127_7922415_12 Autoinducer binding domain K20334 - - 0.00000000000000000000000000000005718 136.0
TH2_k127_7922415_13 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000001484 126.0
TH2_k127_7922415_14 GAF domain - - - 0.000000000000000001045 102.0
TH2_k127_7922415_15 acetyltransferase K22278 - 3.5.1.104 0.000000000000000001078 85.0
TH2_k127_7922415_16 Acetoacetate decarboxylase (ADC) - - - 0.000000000000000002733 85.0
TH2_k127_7922415_17 - - - - 0.000000000008799 69.0
TH2_k127_7922415_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000001518 58.0
TH2_k127_7922415_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 6.376e-197 638.0
TH2_k127_7922415_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 516.0
TH2_k127_7922415_4 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 503.0
TH2_k127_7922415_5 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 477.0
TH2_k127_7922415_6 Uncharacterized protein family, UPF0114 K03535 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 283.0
TH2_k127_7922415_7 Glyoxalase-like domain K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000009581 223.0
TH2_k127_7922415_8 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000002217 193.0
TH2_k127_7922415_9 response regulator - - - 0.00000000000000000000000000000000000000000000000001564 189.0
TH2_k127_7924305_0 Glycogen debranching enzyme - - - 6.318e-234 732.0
TH2_k127_7924305_1 - - - - 0.0000000000000000000000000000000000002273 147.0
TH2_k127_7931841_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 5.591e-277 857.0
TH2_k127_7931841_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 7.287e-220 686.0
TH2_k127_7931841_10 coenzyme F420 binding K07226 - - 0.000000000000000000000000000000000000000000000000000000000000000000003625 238.0
TH2_k127_7931841_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000001948 224.0
TH2_k127_7931841_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000002127 224.0
TH2_k127_7931841_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000003519 224.0
TH2_k127_7931841_14 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.00000000000000000000000000000000000000000000000001475 182.0
TH2_k127_7931841_15 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000003072 148.0
TH2_k127_7931841_16 - - - - 0.00000000000000000000000001163 109.0
TH2_k127_7931841_17 - - - - 0.0000000001459 64.0
TH2_k127_7931841_2 MacB-like periplasmic core domain K09808 - - 3.622e-207 650.0
TH2_k127_7931841_3 Carbon-nitrogen hydrolase K03820 - - 8.607e-206 654.0
TH2_k127_7931841_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 588.0
TH2_k127_7931841_5 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 406.0
TH2_k127_7931841_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 368.0
TH2_k127_7931841_7 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 341.0
TH2_k127_7931841_8 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 307.0
TH2_k127_7931841_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003016 245.0
TH2_k127_7939776_0 radical SAM domain protein - - - 8.067e-252 780.0
TH2_k127_7939776_1 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000000000000000000000000000000000000000000000002204 203.0
TH2_k127_7939776_3 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.0000000000002871 70.0
TH2_k127_7941411_0 AcrB/AcrD/AcrF family - - - 0.0 1442.0
TH2_k127_7941411_1 Protein of unknown function (DUF2914) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 480.0
TH2_k127_7941411_2 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 389.0
TH2_k127_7941411_3 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.000000000000000000000000000000000000000000000000000000008441 201.0
TH2_k127_7941411_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000002992 181.0
TH2_k127_7941411_5 Sterol carrier protein - - - 0.0000000000000000000000000000000000006665 143.0
TH2_k127_7965254_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 422.0
TH2_k127_7965254_1 Alpha amylase, catalytic domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 396.0
TH2_k127_7965254_2 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 387.0
TH2_k127_7965254_3 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 314.0
TH2_k127_7965254_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000002446 250.0
TH2_k127_7965254_5 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000006976 205.0
TH2_k127_7965254_6 FAD binding domain K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000001303 177.0
TH2_k127_7965254_7 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000003556 107.0
TH2_k127_7976464_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 329.0
TH2_k127_7976464_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004596 274.0
TH2_k127_7976464_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000001655 153.0
TH2_k127_7976464_3 - - - - 0.00000000000000000000000001856 112.0
TH2_k127_7976464_4 ACT domain K01653 - 2.2.1.6 0.0000000000000000006558 88.0
TH2_k127_7976464_5 - - - - 0.000000000000000002416 93.0
TH2_k127_7976464_6 haloacid dehalogenase-like hydrolase - - - 0.000000000000000968 82.0
TH2_k127_7976464_7 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000001811 78.0
TH2_k127_7976464_8 - - - - 0.00009613 48.0
TH2_k127_7991760_0 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 581.0
TH2_k127_7991760_1 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 573.0
TH2_k127_7991760_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 433.0
TH2_k127_7991760_5 NAD-dependent epimerase dehydratase K07071 - - 0.0000000000000000000004741 98.0
TH2_k127_7991760_6 cobalamin binding K21089,K21972,K22491 - - 0.000000000000000007569 83.0
TH2_k127_7993218_0 Hsp90 protein K04079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 414.0
TH2_k127_7993218_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000167 251.0
TH2_k127_7993218_2 Excalibur calcium-binding domain - - - 0.000000000000000000000000000000000000000000000000000000001372 205.0
TH2_k127_7993218_3 - - - - 0.00000000000000000000000000000000000001318 147.0
TH2_k127_8002393_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 8.146e-243 753.0
TH2_k127_8002393_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000128 162.0
TH2_k127_8017252_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 524.0
TH2_k127_8017252_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 494.0
TH2_k127_8017252_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000001665 123.0
TH2_k127_8017252_3 Major facilitator Superfamily - - - 0.00000000000000000000000039 113.0
TH2_k127_8017252_4 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.00000009269 62.0
TH2_k127_8021626_0 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 554.0
TH2_k127_8021626_1 Isochorismatase family - - - 0.0006482 53.0
TH2_k127_8030454_0 ATPase associated with various cellular activities, AAA_5 K02584 - - 0.000000000000000000000000123 111.0
TH2_k127_8030454_2 NHL repeat - - - 0.0000000001173 75.0
TH2_k127_8031432_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000003858 98.0
TH2_k127_8050465_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1403.0
TH2_k127_8050465_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1127.0
TH2_k127_8050465_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 1.876e-205 643.0
TH2_k127_8050465_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 470.0
TH2_k127_8050527_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 345.0
TH2_k127_8050527_1 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001452 256.0
TH2_k127_8050527_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000009308 207.0
TH2_k127_8050527_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K00652,K01935 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47,6.3.3.3 0.0000000000000000000000000000000000000000001099 171.0
TH2_k127_8050527_4 belongs to the aldehyde dehydrogenase family K00294,K13821 - 1.2.1.88,1.5.5.2 0.00000000000000000000000005219 107.0
TH2_k127_8062425_0 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 295.0
TH2_k127_8062425_1 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003488 274.0
TH2_k127_8099544_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.816e-287 892.0
TH2_k127_8099544_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K04076,K13525,K17681 - 3.4.21.53 2.028e-278 867.0
TH2_k127_8099544_10 DsrE/DsrF-like family K09004 - - 0.0000000000000000426 90.0
TH2_k127_8099544_2 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 468.0
TH2_k127_8099544_3 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 399.0
TH2_k127_8099544_4 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 389.0
TH2_k127_8099544_6 cellular manganese ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000009262 221.0
TH2_k127_8099544_7 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000000000000000000000000001544 205.0
TH2_k127_8099544_8 response to oxidative stress K04063 - - 0.000000000000000000000000000000002434 129.0
TH2_k127_8099544_9 Cytochrome c K12263 - - 0.000000000000000000005338 98.0
TH2_k127_8104215_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1357.0
TH2_k127_8104215_1 Surface antigen K07277 - - 0.0 1116.0
TH2_k127_8104215_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 1.599e-269 834.0
TH2_k127_8104215_3 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 486.0
TH2_k127_8104215_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 357.0
TH2_k127_8104215_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.000000000000000000000000000000000000000000000000000000000000131 218.0
TH2_k127_8104215_6 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000000006346 203.0
TH2_k127_8104215_7 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814,K13815 - - 0.000000000000000007622 91.0
TH2_k127_8111773_0 Evidence 2b Function of strongly homologous gene K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 531.0
TH2_k127_8111773_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K07052 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 387.0
TH2_k127_8111773_2 Histidine kinase K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 244.0
TH2_k127_8111773_3 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001253 225.0
TH2_k127_8132492_0 NAD dependent epimerase dehydratase family protein K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000142 253.0
TH2_k127_8132492_1 GHMP kinases N terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000009868 240.0
TH2_k127_8132492_2 SMART Chromosomal replication initiator DnaA domain - - - 0.0000000000000000000000000000000000000001284 152.0
TH2_k127_8132492_3 PFAM transposase IS116 IS110 IS902 family - - - 0.00000000000000007075 81.0
TH2_k127_8149297_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000153 293.0
TH2_k127_8149297_1 Methyltransferase domain - - - 0.000000000000000000001941 105.0
TH2_k127_8149297_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000004642 93.0
TH2_k127_8171515_0 Transposase DDE domain - - - 0.0000000009493 70.0
TH2_k127_8171515_1 Phage integrase family - - - 0.000000001938 59.0
TH2_k127_8171515_2 - - - - 0.0000003519 58.0
TH2_k127_8171515_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00008771 51.0
TH2_k127_820722_0 Homeodomain-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 542.0
TH2_k127_820722_1 Protein of unknown function (DUF3096) - - - 0.000000000007118 67.0
TH2_k127_8220224_0 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000004775 246.0
TH2_k127_8220224_1 EamA-like transporter family - - - 0.000000000000000000000000000005322 124.0
TH2_k127_8220224_2 Histidine phosphatase superfamily (branch 1) K08296 - - 0.000000000000000000000000000234 121.0
TH2_k127_8235138_0 Protein of unknown function (DUF5131) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 347.0
TH2_k127_8235138_1 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000003837 193.0
TH2_k127_8235138_2 restriction modification system DNA specificity K01154 - 3.1.21.3 0.000000000000000000000000000000000003434 146.0
TH2_k127_8235138_3 COGs COG5573 nucleic-acid-binding protein contains PIN domain - - - 0.000000000000000000000000000000003131 133.0
TH2_k127_8235138_4 Protein of unknown function (DUF5131) - - - 0.00000000000000000001119 102.0
TH2_k127_8235138_5 Putative RNA methylase family UPF0020 K03427 - 2.1.1.72 0.000000000000001671 80.0
TH2_k127_8235138_6 - - - - 0.00000000000001176 79.0
TH2_k127_8235138_7 Aldo/keto reductase family - - - 0.00000003488 55.0
TH2_k127_8285021_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.513e-248 769.0
TH2_k127_8285021_1 heme binding K00463 - 1.13.11.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 572.0
TH2_k127_8285021_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 372.0
TH2_k127_8285021_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 301.0
TH2_k127_8296162_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 1.958e-218 679.0
TH2_k127_8296162_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.12e-202 647.0
TH2_k127_8296162_10 translation initiation factor activity K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001126 188.0
TH2_k127_8296162_11 conserved protein (DUF2132) K06867 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000002442 145.0
TH2_k127_8296162_13 nitric oxide dioxygenase activity - - - 0.0000000000000000000000002672 111.0
TH2_k127_8296162_14 domain, Protein K18491 - - 0.0000000000000000004133 95.0
TH2_k127_8296162_3 PHP domain protein K01624,K07053 - 3.1.3.97,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 408.0
TH2_k127_8296162_4 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006081 415.0
TH2_k127_8296162_5 tRNA (guanine(37)-N(1))-methyltransferase activity K01091,K01633,K15429 - 1.13.11.81,2.1.1.228,3.1.3.18,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 369.0
TH2_k127_8296162_6 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000851 277.0
TH2_k127_8296162_7 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002524 262.0
TH2_k127_8296162_8 protein histidine kinase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000039 282.0
TH2_k127_8296162_9 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002683 254.0
TH2_k127_83035_0 Methionine biosynthesis protein MetW - - - 0.0000000000000000000002178 105.0
TH2_k127_83035_1 glycosyl transferase group 1 - - - 0.0000001815 60.0
TH2_k127_8303613_0 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000003049 263.0
TH2_k127_8306119_0 ATPase, AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 596.0
TH2_k127_8306119_1 Transcription termination factor nusG - - - 0.00000000000000000000000000000000000000000008076 165.0
TH2_k127_8306119_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000002489 71.0
TH2_k127_8310018_0 catechol 2,3-dioxygenase activity K07104 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 287.0
TH2_k127_8310018_1 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003922 266.0
TH2_k127_8310018_2 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000000000000000004943 156.0
TH2_k127_8310018_3 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000129 136.0
TH2_k127_8310018_4 protein disulfide oxidoreductase activity - - - 0.0000000000000000000000000000007642 124.0
TH2_k127_831171_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 576.0
TH2_k127_831171_1 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 354.0
TH2_k127_83300_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1157.0
TH2_k127_83300_1 phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 531.0
TH2_k127_83300_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 411.0
TH2_k127_83300_3 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000737 343.0
TH2_k127_8332743_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00322,K00382 - 1.6.1.1,1.8.1.4 1.013e-196 626.0
TH2_k127_8332743_1 Multicopper oxidase K00368,K22349 - 1.16.3.3,1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 558.0
TH2_k127_8332743_10 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000974 83.0
TH2_k127_8332743_11 RNA recognition motif - - - 0.000000000002196 67.0
TH2_k127_8332743_13 PFAM Fibronectin type III - - - 0.000003538 56.0
TH2_k127_8332743_2 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 497.0
TH2_k127_8332743_3 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 370.0
TH2_k127_8332743_4 - K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 366.0
TH2_k127_8332743_5 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 348.0
TH2_k127_8332743_6 amino acid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 353.0
TH2_k127_8332743_8 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000006122 199.0
TH2_k127_8334522_0 regulation of ruffle assembly - - - 0.00000000000000000000000000000000000000000000000003374 187.0
TH2_k127_8334522_1 - - - - 0.000000000000000000000000000000000000000001728 171.0
TH2_k127_8334522_2 PFAM Patatin K07001 - - 0.00000145 60.0
TH2_k127_8334522_3 Patatin-like phospholipase - - - 0.00000172 61.0
TH2_k127_8335665_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1555.0
TH2_k127_8335665_1 HlyD family secretion protein K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 322.0
TH2_k127_8355764_0 Secretin and TonB N terminus short domain K02453 - - 9.064e-199 646.0
TH2_k127_8355764_1 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000000000001798 209.0
TH2_k127_8355764_2 Type II secretory pathway, pseudopilin - - - 0.0000000000000000000000000000000000000000000164 167.0
TH2_k127_8355764_3 Type II secretion system protein G K02456 - - 0.000000000000000000000000000000003044 132.0
TH2_k127_8355764_4 - - - - 0.0000000001397 64.0
TH2_k127_8355764_5 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00002443 47.0
TH2_k127_8358599_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 613.0
TH2_k127_8358599_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 610.0
TH2_k127_8358599_2 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 583.0
TH2_k127_8358599_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 329.0
TH2_k127_8358599_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000004236 230.0
TH2_k127_8359120_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 324.0
TH2_k127_8359120_1 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000431 72.0
TH2_k127_8360485_0 AMP-dependent synthetase - - - 6.25e-254 829.0
TH2_k127_8419822_0 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 1.638e-268 838.0
TH2_k127_8419822_1 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003709 270.0
TH2_k127_8419822_3 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000000000002944 133.0
TH2_k127_8486602_0 Glycosyl hydrolase family 57 - - - 0.0 1066.0
TH2_k127_8486602_1 phosphorelay signal transduction system - - - 8.983e-216 679.0
TH2_k127_8486602_10 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.00000001004 57.0
TH2_k127_8486602_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 593.0
TH2_k127_8486602_3 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 585.0
TH2_k127_8486602_4 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 512.0
TH2_k127_8486602_5 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 499.0
TH2_k127_8486602_6 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 501.0
TH2_k127_8486602_7 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 354.0
TH2_k127_8486602_8 Polynucleotide adenylyltransferase K00974 - 2.7.7.72 0.000000000000000000000000000000001388 135.0
TH2_k127_8486602_9 - - - - 0.0000000000000000000000000000208 122.0
TH2_k127_8491981_0 GXGXG motif - - - 7.948e-285 900.0
TH2_k127_8491981_1 Glutamate synthase - - - 6.909e-194 611.0
TH2_k127_8533758_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 597.0
TH2_k127_8533758_1 PFAM Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 587.0
TH2_k127_8538023_0 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000009192 249.0
TH2_k127_8538023_1 - - - - 0.00000000000000000000000000000000000000000000000000000002399 206.0
TH2_k127_8538023_2 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000002388 112.0
TH2_k127_8538023_3 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000002162 111.0
TH2_k127_8538023_4 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000003401 112.0
TH2_k127_8538023_5 Protein of unknown function (DUF1254) - - - 0.00000000000000226 78.0
TH2_k127_8541697_1 regulation of ruffle assembly - - - 0.0000000000000000000000000000000004959 142.0
TH2_k127_8541697_2 Zn-dependent protease - - - 0.00004089 48.0
TH2_k127_857239_0 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 353.0
TH2_k127_857239_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003955 241.0
TH2_k127_857239_2 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000000004154 220.0
TH2_k127_857239_3 Amino acid permease K03294 - - 0.000008665 53.0
TH2_k127_8574986_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 1.372e-235 732.0
TH2_k127_8574986_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 573.0
TH2_k127_8574986_10 Met-10+ like-protein - - - 0.000000000000000000000000000000000000000009269 162.0
TH2_k127_8574986_13 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000008678 102.0
TH2_k127_8574986_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00008055 46.0
TH2_k127_8574986_16 Outer membrane lipoprotein Slp family K07285 - - 0.0004983 49.0
TH2_k127_8574986_17 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0005016 42.0
TH2_k127_8574986_2 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 477.0
TH2_k127_8574986_3 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 439.0
TH2_k127_8574986_4 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 300.0
TH2_k127_8574986_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003126 287.0
TH2_k127_8574986_6 protein transport across the cell outer membrane K02453,K03219 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005519 260.0
TH2_k127_8574986_7 Belongs to the HesB IscA family K15724 - - 0.000000000000000000000000000000000000000000000000000749 186.0
TH2_k127_8574986_8 CYTH - - - 0.00000000000000000000000000000000000000000000004207 188.0
TH2_k127_8574986_9 - - - - 0.00000000000000000000000000000000000000000000929 168.0
TH2_k127_8592731_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 582.0
TH2_k127_8592731_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 493.0
TH2_k127_8592731_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 372.0
TH2_k127_8592731_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 307.0
TH2_k127_8592731_4 SprT-like family K02742 - - 0.00000000000000000000000000000000000000000000000000000000001828 214.0
TH2_k127_8592731_5 sigma factor antagonist activity K20977 - - 0.000000000000000000000000000000000003091 159.0
TH2_k127_8592731_6 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000001908 118.0
TH2_k127_8597065_0 Asparagine synthase K01953 - 6.3.5.4 1.493e-213 676.0
TH2_k127_8597065_1 Protein conserved in bacteria K06320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 354.0
TH2_k127_8597065_2 Pfam Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004373 250.0
TH2_k127_8622306_0 Molydopterin dinucleotide binding domain K00302,K10814 - 1.4.99.5,1.5.3.1 0.0 1467.0
TH2_k127_8622306_1 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 0.0 1047.0
TH2_k127_8622306_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342,K05575 - 1.6.5.3 4.047e-273 844.0
TH2_k127_8622306_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 2.783e-265 824.0
TH2_k127_8622306_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 5.618e-211 655.0
TH2_k127_8622306_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008261 371.0
TH2_k127_8622306_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001691 242.0
TH2_k127_8622306_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000000007985 166.0
TH2_k127_8638996_0 TIGRFAM RecB family nuclease - - - 2.327e-194 642.0
TH2_k127_8638996_3 Protein of unknown function (DUF429) - - - 0.000000000000000000000000000000000000000000000000003464 190.0
TH2_k127_8638996_4 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.00000000000000000000000005149 114.0
TH2_k127_8749123_0 type III restriction protein res subunit K01153 - 3.1.21.3 0.0 1221.0
TH2_k127_8749123_1 N-6 DNA methylase K03427 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006823 273.0
TH2_k127_8780287_0 GHKL domain K13598 - 2.7.13.3 0.0 1151.0
TH2_k127_8780287_1 Bacterial regulatory protein, Fis family K13599 - - 1.401e-236 739.0
TH2_k127_8780287_2 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 445.0
TH2_k127_8780287_3 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000347 248.0
TH2_k127_8780287_4 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.0000000000000000000000000000000000000000000000000000000000001548 215.0
TH2_k127_8780287_5 Domain of unknown function (DUF1844) - - - 0.000000000000000000000000000000000000000003121 158.0
TH2_k127_8812134_0 PFAM beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 434.0
TH2_k127_8812134_1 Zn peptidase - - - 0.000000000000000000000000000001315 136.0
TH2_k127_8812134_2 PIN domain K07063 - - 0.00000000000000000001033 96.0
TH2_k127_8812134_3 - - - - 0.0000000000003084 75.0
TH2_k127_8812134_4 N-6 DNA Methylase K03427 - 2.1.1.72 0.00000001723 58.0
TH2_k127_8812134_5 regulation of methylation-dependent chromatin silencing K07454 - - 0.0000005258 52.0
TH2_k127_8812134_7 SpoVT / AbrB like domain - - - 0.0003157 46.0
TH2_k127_8841719_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 481.0
TH2_k127_8841719_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 350.0
TH2_k127_8848751_0 Hsp70 protein K04043,K04044 - - 1.981e-236 734.0
TH2_k127_8848751_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 393.0
TH2_k127_8848751_2 Iron-sulphur cluster assembly - - - 0.000000000000000000000000000000002201 130.0
TH2_k127_886280_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 452.0
TH2_k127_886280_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 367.0
TH2_k127_886280_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 293.0
TH2_k127_886280_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000001543 200.0
TH2_k127_886280_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000002843 201.0
TH2_k127_886280_5 heat shock protein binding - - - 0.000000000000000000000000000000000000000001483 162.0
TH2_k127_886280_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.000000004011 59.0
TH2_k127_906451_0 belongs to the aldehyde dehydrogenase family K00294,K13821 - 1.2.1.88,1.5.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 482.0
TH2_k127_906451_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 440.0
TH2_k127_906451_2 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 416.0
TH2_k127_906451_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 300.0
TH2_k127_906451_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.00000000000000000000000000000000000000000004036 162.0
TH2_k127_950533_0 Belongs to the Pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 316.0
TH2_k127_950533_1 NUDIX domain - - - 0.00000000000000000000000000000000000000000000003487 175.0
TH2_k127_979120_0 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 5.97e-215 678.0
TH2_k127_979120_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 510.0
TH2_k127_979120_2 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000001193 208.0