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Overview

ID MAG03920
Name TH2_bin.6
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Myxococcota
Class Polyangia
Order Palsa-1104
Family Palsa-1104
Genus JBDTCO01
Species
Assembly information
Completeness (%) 88.2
Contamination (%) 1.94
GC content (%) 70.0
N50 (bp) 17,925
Genome size (bp) 5,080,606

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3717

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1041693_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.843e-201 636.0
TH2_k127_1041693_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971 604.0
TH2_k127_1041693_10 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000005286 222.0
TH2_k127_1041693_11 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000004118 213.0
TH2_k127_1041693_12 Rhomboid family K07059 - - 0.000000000000000000000000000000000000000000000002131 190.0
TH2_k127_1041693_13 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000002436 134.0
TH2_k127_1041693_16 Phosphate acyltransferases - - - 0.000000000000001468 89.0
TH2_k127_1041693_17 Tetratricopeptide repeat K09667 GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252 2.4.1.255 0.000000000001788 79.0
TH2_k127_1041693_2 AMP-binding enzyme C-terminal domain K22319 - 6.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 530.0
TH2_k127_1041693_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 382.0
TH2_k127_1041693_4 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 345.0
TH2_k127_1041693_5 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 331.0
TH2_k127_1041693_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 329.0
TH2_k127_1041693_7 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 316.0
TH2_k127_1041693_8 Cell division protein FtsI penicillin-binding protein 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000203 295.0
TH2_k127_1041693_9 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002537 301.0
TH2_k127_1046489_0 Type III restriction enzyme, res subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001159 304.0
TH2_k127_1046489_1 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001252 252.0
TH2_k127_1046489_2 Belongs to the AAA ATPase family K08900 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006810,GO:0006996,GO:0007005,GO:0007006,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017004,GO:0017062,GO:0017111,GO:0019866,GO:0022607,GO:0022857,GO:0022884,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032978,GO:0032979,GO:0033036,GO:0033108,GO:0033365,GO:0034551,GO:0034613,GO:0034622,GO:0042623,GO:0042886,GO:0042887,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0051131,GO:0051179,GO:0051204,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065003,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000000000000000000000003977 182.0
TH2_k127_1046489_3 Protein of unknown function (DUF790) K09744 - - 0.000000000000000000000000000000003963 143.0
TH2_k127_1046489_4 Domain of unknown function (DUF4143) - - - 0.000000000000000000003747 108.0
TH2_k127_1046489_5 - - - - 0.000000000000001577 83.0
TH2_k127_1046489_7 Belongs to the AAA ATPase family K13525 - - 0.000006265 54.0
TH2_k127_1046489_8 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00005363 51.0
TH2_k127_1058358_0 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 3.796e-195 617.0
TH2_k127_1058358_1 type IV pilus secretin PilQ K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 616.0
TH2_k127_1058358_10 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 327.0
TH2_k127_1058358_11 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 324.0
TH2_k127_1058358_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004737 290.0
TH2_k127_1058358_13 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001353 266.0
TH2_k127_1058358_14 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000005729 246.0
TH2_k127_1058358_15 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000268 209.0
TH2_k127_1058358_16 Poly(3-hydroxybutyrate) depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000001209 202.0
TH2_k127_1058358_17 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000002692 162.0
TH2_k127_1058358_18 transporter component K07112 - - 0.0000000000000000000000000000000000002775 149.0
TH2_k127_1058358_19 - K07112 - - 0.000000000000000000000000000000000001363 153.0
TH2_k127_1058358_2 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009473 533.0
TH2_k127_1058358_21 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000001849 132.0
TH2_k127_1058358_23 Roadblock/LC7 domain - - - 0.00000000000000000000000000000634 122.0
TH2_k127_1058358_24 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000006725 119.0
TH2_k127_1058358_25 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000002291 120.0
TH2_k127_1058358_26 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000001776 119.0
TH2_k127_1058358_28 - - - - 0.0000000000000000000000009347 119.0
TH2_k127_1058358_29 Phosphopantetheine attachment site - - - 0.00000000000000000002516 94.0
TH2_k127_1058358_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 477.0
TH2_k127_1058358_30 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000002261 93.0
TH2_k127_1058358_31 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000894 101.0
TH2_k127_1058358_32 transferase activity, transferring acyl groups - - - 0.00000000000000000147 98.0
TH2_k127_1058358_34 Pilus assembly protein, PilO K02664 - - 0.00000000002518 75.0
TH2_k127_1058358_35 interspecies interaction between organisms K18353 - - 0.0000000003654 71.0
TH2_k127_1058358_36 Pilus assembly protein, PilP K02665 - - 0.000000001708 69.0
TH2_k127_1058358_37 23S rRNA-intervening sequence protein - - - 0.00000007876 59.0
TH2_k127_1058358_4 membrane protein involved in D-alanine K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 484.0
TH2_k127_1058358_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 450.0
TH2_k127_1058358_6 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 437.0
TH2_k127_1058358_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 424.0
TH2_k127_1058358_8 pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 353.0
TH2_k127_1058358_9 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 337.0
TH2_k127_1106435_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 452.0
TH2_k127_1114803_0 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000002811 250.0
TH2_k127_1114803_1 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000000001516 194.0
TH2_k127_1114803_2 abc transporter atp-binding protein K01990 - - 0.0000000000000000000000000000000000000000005969 166.0
TH2_k127_1114803_3 NosL - - - 0.0000000000000008743 84.0
TH2_k127_1114803_4 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.0001904 53.0
TH2_k127_1123414_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 533.0
TH2_k127_1123414_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 445.0
TH2_k127_1123414_10 membrane K08973 - - 0.000000000000000000000000000001718 139.0
TH2_k127_1123414_11 B domain of TMEM189, localisation domain K20417 - 1.14.19.43 0.0000000000000709 83.0
TH2_k127_1123414_12 ABC transporter substrate binding protein K01989 - - 0.0000000000009912 79.0
TH2_k127_1123414_13 6-phosphogluconolactonase activity - - - 0.000000000001196 81.0
TH2_k127_1123414_14 Pfs, NACHT, and Ankyrin domain protein - - - 0.00000000002139 76.0
TH2_k127_1123414_15 TPR repeat - - - 0.00003173 55.0
TH2_k127_1123414_2 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009303 320.0
TH2_k127_1123414_4 Iron/manganese superoxide dismutases, alpha-hairpin domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002573 283.0
TH2_k127_1123414_5 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005717 290.0
TH2_k127_1123414_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000001209 229.0
TH2_k127_1123414_7 Belongs to the Dps family - - - 0.000000000000000000000000000000000000000000000000002176 206.0
TH2_k127_1123414_8 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000001106 153.0
TH2_k127_1123414_9 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000138 141.0
TH2_k127_1135746_0 4Fe-4S single cluster domain K06937 - - 2.839e-271 854.0
TH2_k127_1135746_1 PFAM Cobalamin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001728 295.0
TH2_k127_1135746_2 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001175 284.0
TH2_k127_1135746_3 Pfam Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000004097 207.0
TH2_k127_1135746_4 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00002815 49.0
TH2_k127_117292_0 Involved in the tonB-independent uptake of proteins K03641 - - 2.448e-238 771.0
TH2_k127_117292_1 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 597.0
TH2_k127_117292_2 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 555.0
TH2_k127_117292_3 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000001014 233.0
TH2_k127_117292_5 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000008368 106.0
TH2_k127_117292_6 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000009316 98.0
TH2_k127_117292_7 PilZ domain - - - 0.00000000000004205 77.0
TH2_k127_117292_9 TonB dependent receptor - - - 0.00006296 56.0
TH2_k127_1177927_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 4.115e-205 651.0
TH2_k127_1177927_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 1.457e-197 623.0
TH2_k127_1177927_10 PEGA domain - - - 0.00000000000002652 83.0
TH2_k127_1177927_12 - - - - 0.0000002561 64.0
TH2_k127_1177927_2 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 636.0
TH2_k127_1177927_3 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0008114,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009737,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0033993,GO:0034641,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097305,GO:1901135,GO:1901360,GO:1901564,GO:1901700 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 593.0
TH2_k127_1177927_4 DEAD/H associated K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 461.0
TH2_k127_1177927_5 Protein conserved in bacteria K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 361.0
TH2_k127_1177927_6 - - - - 0.00000000000000000000000000000000000000000000000000000000007786 212.0
TH2_k127_1177927_7 Protein of unknown function (DUF1318) - - - 0.00000000000000000000000000001764 134.0
TH2_k127_1177927_9 amine dehydrogenase activity - - - 0.00000000000000002041 97.0
TH2_k127_1197671_0 Serine Threonine protein kinase K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000007025 217.0
TH2_k127_1197671_1 Kelch motif - - - 0.000000000000000000000000000005223 136.0
TH2_k127_1198520_0 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000006126 156.0
TH2_k127_1198520_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000002488 113.0
TH2_k127_1198520_3 Ferredoxin K17992 - 1.12.1.3 0.000000000008429 70.0
TH2_k127_1198520_4 Rossmann-like domain - - - 0.000000001376 63.0
TH2_k127_1198520_5 oxidoreductase activity K07114 - - 0.00004194 54.0
TH2_k127_1199079_0 Protein-disulfide isomerase - - - 1.677e-211 687.0
TH2_k127_1199079_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 621.0
TH2_k127_1199079_10 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000001111 117.0
TH2_k127_1199079_11 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000000000311 105.0
TH2_k127_1199079_12 PTS system fructose IIA component - - - 0.00000000000007597 76.0
TH2_k127_1199079_13 PFAM Glutaredoxin 2 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000001688 70.0
TH2_k127_1199079_14 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000009088 69.0
TH2_k127_1199079_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 607.0
TH2_k127_1199079_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 370.0
TH2_k127_1199079_4 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003182 274.0
TH2_k127_1199079_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000355 192.0
TH2_k127_1199079_6 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000004068 177.0
TH2_k127_1199079_7 Thioredoxin - - - 0.00000000000000000000000000000000000000000005307 184.0
TH2_k127_1199079_8 Thioredoxin-like - - - 0.00000000000000000000000000001838 132.0
TH2_k127_1199079_9 PFAM response regulator receiver K07657,K07658 - - 0.00000000000000000000000001072 123.0
TH2_k127_1228390_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.669e-239 748.0
TH2_k127_1228390_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.616e-231 724.0
TH2_k127_1228390_10 protein conserved in bacteria (DUF2168) - - - 0.000000000000000000000000000000000000000002063 163.0
TH2_k127_1228390_11 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000007268 146.0
TH2_k127_1228390_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000002859 158.0
TH2_k127_1228390_13 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000001715 121.0
TH2_k127_1228390_14 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000001977 108.0
TH2_k127_1228390_15 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000009676 113.0
TH2_k127_1228390_16 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000151 113.0
TH2_k127_1228390_17 - - - - 0.0000000000000000000007793 97.0
TH2_k127_1228390_18 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000000000009285 106.0
TH2_k127_1228390_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 360.0
TH2_k127_1228390_20 Belongs to the UPF0109 family K06960 - - 0.0000000000000000001011 94.0
TH2_k127_1228390_21 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000004608 92.0
TH2_k127_1228390_22 Sulfatase-modifying factor enzyme 1 - - - 0.0000003323 62.0
TH2_k127_1228390_23 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) K02109 - - 0.000009172 57.0
TH2_k127_1228390_24 pyrroloquinoline quinone binding - - - 0.00004516 53.0
TH2_k127_1228390_25 ABC-2 family transporter protein K01992 - - 0.0007228 52.0
TH2_k127_1228390_3 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 350.0
TH2_k127_1228390_4 ABC transporter K01990,K20459 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 303.0
TH2_k127_1228390_5 (ABC) transporter K01990,K20459 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 300.0
TH2_k127_1228390_6 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000002149 269.0
TH2_k127_1228390_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004382 270.0
TH2_k127_1228390_8 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000001116 179.0
TH2_k127_1228390_9 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000002114 163.0
TH2_k127_123505_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008342 539.0
TH2_k127_123505_1 regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000664 231.0
TH2_k127_123505_2 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000003302 204.0
TH2_k127_123505_3 - - - - 0.000000000000000000000000000000000000000000006113 168.0
TH2_k127_123505_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000002275 156.0
TH2_k127_1258016_0 acyl-CoA dehydrogenase K09456,K20035 - - 1.111e-264 828.0
TH2_k127_1258016_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 330.0
TH2_k127_1258016_2 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000002767 228.0
TH2_k127_1258016_3 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000000000000000000000000435 138.0
TH2_k127_1258016_4 Predicted permease K07089 - - 0.00000000000000000000000000000001397 138.0
TH2_k127_1258016_5 Ceramidase - - - 0.00000000000000002422 91.0
TH2_k127_1258016_6 Transposase IS4 family protein - - - 0.0003133 43.0
TH2_k127_1273841_0 Peptidase family M41 K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 548.0
TH2_k127_1273841_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000006954 233.0
TH2_k127_1273841_2 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000000000000000000000004558 188.0
TH2_k127_1273841_3 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000000000000000000000003951 138.0
TH2_k127_1290101_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 486.0
TH2_k127_1290101_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 371.0
TH2_k127_1304440_0 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 362.0
TH2_k127_1304440_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000002494 202.0
TH2_k127_1304440_2 Amidohydrolase K07045 - - 0.000000000000000000000000000000000009532 152.0
TH2_k127_1304440_3 Galactose oxidase, central domain - - - 0.000000000000000000000000007175 123.0
TH2_k127_1312874_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1035.0
TH2_k127_1312874_1 protein involved in exopolysaccharide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 627.0
TH2_k127_1312874_10 Secondary thiamine-phosphate synthase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001157 259.0
TH2_k127_1312874_11 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000000002092 248.0
TH2_k127_1312874_12 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000001228 218.0
TH2_k127_1312874_13 Phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000003048 215.0
TH2_k127_1312874_14 Sensors of blue-light using FAD - - - 0.000000000000000000000000000000000000000000000000000000001608 211.0
TH2_k127_1312874_15 UvrD REP helicase K03582 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000001498 210.0
TH2_k127_1312874_16 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000000003127 189.0
TH2_k127_1312874_17 cobalamin binding K03496,K22491 - - 0.0000000000000000000000000000000000000000000003076 177.0
TH2_k127_1312874_18 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000000000000000000000165 169.0
TH2_k127_1312874_19 - - - - 0.00000000000000000000000000000000000002406 161.0
TH2_k127_1312874_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 603.0
TH2_k127_1312874_20 cellulose binding - - - 0.0000000000000000000001323 115.0
TH2_k127_1312874_21 CAAX protease self-immunity K07052 - - 0.0000000005421 71.0
TH2_k127_1312874_3 Viral (Superfamily 1) RNA helicase K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 453.0
TH2_k127_1312874_4 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 422.0
TH2_k127_1312874_5 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 404.0
TH2_k127_1312874_6 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 396.0
TH2_k127_1312874_7 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 291.0
TH2_k127_1312874_8 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004697 280.0
TH2_k127_1312874_9 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001187 289.0
TH2_k127_1348344_0 LicD family - - - 0.0000001532 61.0
TH2_k127_1362461_0 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000004025 215.0
TH2_k127_1362461_1 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000006815 224.0
TH2_k127_1362461_10 chaperone-mediated protein folding - - - 0.00000000000000006576 93.0
TH2_k127_1362461_11 Peptidoglycan-synthase activator LpoB - - - 0.0000000000000001475 93.0
TH2_k127_1362461_13 Belongs to the thioredoxin family K03671 - - 0.00007901 46.0
TH2_k127_1362461_3 N-acetylmuramoyl-L-alanine amidase - - - 0.00000000000000000000000000000000000000000006336 174.0
TH2_k127_1362461_4 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000001581 173.0
TH2_k127_1362461_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000002567 143.0
TH2_k127_1362461_6 NHL repeat - - - 0.0000000000000000000000000001549 134.0
TH2_k127_1362461_7 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000005276 114.0
TH2_k127_1362461_8 AI-2E family transporter - - - 0.0000000000000000000000001431 119.0
TH2_k127_1362461_9 Peptidase C26 K07010 - - 0.0000000000000000000141 104.0
TH2_k127_1364588_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 552.0
TH2_k127_1364588_1 Bacterial regulatory protein, Fis family K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 451.0
TH2_k127_1364588_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 359.0
TH2_k127_1364588_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000009341 169.0
TH2_k127_1364588_4 - - - - 0.0000000000000000000000000000000000000000000003836 179.0
TH2_k127_1364588_6 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.0000000000000000000000004304 116.0
TH2_k127_1367150_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 417.0
TH2_k127_1367150_1 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 343.0
TH2_k127_1367150_2 long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006402 268.0
TH2_k127_1367150_3 long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000000000000000000000000000005662 210.0
TH2_k127_1367150_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000007693 185.0
TH2_k127_1380615_0 Receptor - - - 6.034e-266 842.0
TH2_k127_1380615_1 Prolyl oligopeptidase family - - - 3.659e-251 796.0
TH2_k127_1380615_2 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 557.0
TH2_k127_1380615_3 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 484.0
TH2_k127_1380615_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 339.0
TH2_k127_1380615_5 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 304.0
TH2_k127_1380615_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000003048 205.0
TH2_k127_1421377_0 Protein kinase; unclassified specificity. K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 342.0
TH2_k127_1436788_0 Bacterial transcriptional repressor C-terminal K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003429 280.0
TH2_k127_1436788_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000002104 220.0
TH2_k127_1436788_2 amine dehydrogenase activity - - - 0.00000000000000000000004421 115.0
TH2_k127_1436788_3 - - - - 0.0000000000000003216 85.0
TH2_k127_1436788_4 TPR repeat - - - 0.0000007086 59.0
TH2_k127_144147_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 367.0
TH2_k127_144147_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 334.0
TH2_k127_144147_2 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 304.0
TH2_k127_144147_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001637 258.0
TH2_k127_144147_4 YceI-like domain - - - 0.00000000000000000000000000000000000000001075 162.0
TH2_k127_144147_5 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.00000000000000000000000000000000000000002821 164.0
TH2_k127_146141_0 FabA-like domain - - - 0.0 1154.0
TH2_k127_146141_1 Major Facilitator Superfamily - - - 4.978e-233 733.0
TH2_k127_146141_10 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000002328 198.0
TH2_k127_146141_11 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000003856 174.0
TH2_k127_146141_12 - - - - 0.000009703 55.0
TH2_k127_146141_2 PFAM AMP-dependent synthetase and ligase K22319 - 6.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 572.0
TH2_k127_146141_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 462.0
TH2_k127_146141_4 PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III K22317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006166 390.0
TH2_k127_146141_5 3-Beta hydroxysteroid dehydrogenase isomerase K21271,K22320 - 1.1.1.394,1.1.1.412 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 389.0
TH2_k127_146141_6 PFAM alpha beta hydrolase fold K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 376.0
TH2_k127_146141_7 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001925 286.0
TH2_k127_146141_8 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000521 274.0
TH2_k127_146141_9 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000002444 226.0
TH2_k127_1465542_0 sequence-specific DNA binding - - - 0.000299 52.0
TH2_k127_1465542_1 Hydrolase of the alpha beta-hydrolase K07020 - - 0.0004279 53.0
TH2_k127_1472013_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 539.0
TH2_k127_1472013_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 533.0
TH2_k127_1472013_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000000000586 141.0
TH2_k127_1472013_11 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000004882 117.0
TH2_k127_1472013_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000009179 96.0
TH2_k127_1472013_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 453.0
TH2_k127_1472013_3 Arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 409.0
TH2_k127_1472013_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 374.0
TH2_k127_1472013_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 306.0
TH2_k127_1472013_6 - - - - 0.0000000000000000000000000000000000000000000000006882 186.0
TH2_k127_1472013_7 - - - - 0.000000000000000000000000000000000000000000003291 167.0
TH2_k127_1472013_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000004283 169.0
TH2_k127_1472013_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.0000000000000000000000000000000000000002329 172.0
TH2_k127_1472532_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 430.0
TH2_k127_1472532_1 helix_turn_helix, Lux Regulon K03556 GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030246,GO:0031323,GO:0031326,GO:0042802,GO:0044238,GO:0048031,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070492,GO:0071704,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 365.0
TH2_k127_1472986_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.405e-290 907.0
TH2_k127_1472986_1 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 3.112e-244 765.0
TH2_k127_1472986_10 PLD-like domain - - - 0.0000000000000000000000000000000000000000008671 170.0
TH2_k127_1472986_11 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000001127 166.0
TH2_k127_1472986_12 PAS fold - - - 0.0000000000000000000000000000000008606 151.0
TH2_k127_1472986_13 zinc-ribbon domain - - - 0.000000000000000000000000000000004698 150.0
TH2_k127_1472986_14 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000001082 123.0
TH2_k127_1472986_15 Tetratricopeptide TPR_2 repeat protein - - - 0.00000003116 65.0
TH2_k127_1472986_2 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 516.0
TH2_k127_1472986_3 Selenocysteine-specific translation elongation factor K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 505.0
TH2_k127_1472986_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 400.0
TH2_k127_1472986_5 drug transmembrane transporter activity K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009612 376.0
TH2_k127_1472986_6 Major Facilitator Superfamily K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001331 283.0
TH2_k127_1472986_7 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000006278 216.0
TH2_k127_1472986_9 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000008817 191.0
TH2_k127_1535055_0 Glycoside-hydrolase family GH114 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 440.0
TH2_k127_1535055_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 392.0
TH2_k127_1535055_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001213 256.0
TH2_k127_1535055_3 TPR repeat - - - 0.000000000006441 79.0
TH2_k127_1552360_0 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001358 290.0
TH2_k127_1552360_1 Acetyltransferase (GNAT) domain K22479 - - 0.00000000000000000000000000000000000000001059 175.0
TH2_k127_1552360_2 Protein of unknown function (DUF861) K06995 - - 0.00000000000000002042 89.0
TH2_k127_1608927_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 378.0
TH2_k127_1608927_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 325.0
TH2_k127_1608927_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000001148 121.0
TH2_k127_1608927_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000001146 111.0
TH2_k127_1630368_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 497.0
TH2_k127_1670500_0 Outer membrane protein beta-barrel family - - - 2.667e-247 796.0
TH2_k127_1670500_1 Peptidase family M3 K01392 - 3.4.24.15 1.393e-231 746.0
TH2_k127_1670500_10 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000000000000000004749 142.0
TH2_k127_1670500_11 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000428 143.0
TH2_k127_1670500_12 Belongs to the ArsC family - - - 0.0000000000000000000000000007955 123.0
TH2_k127_1670500_2 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 421.0
TH2_k127_1670500_3 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 409.0
TH2_k127_1670500_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 347.0
TH2_k127_1670500_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000001032 239.0
TH2_k127_1670500_6 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000001925 211.0
TH2_k127_1670500_7 TonB system transport protein ExbB TolQ K03561 - - 0.00000000000000000000000000000000000000000000000000000005197 215.0
TH2_k127_1670500_8 - - - - 0.00000000000000000000000000000000000000000000000000007582 189.0
TH2_k127_1670500_9 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000000000001187 145.0
TH2_k127_1690456_0 ATPase family associated with various cellular activities (AAA) - - - 2.837e-207 662.0
TH2_k127_1690456_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 384.0
TH2_k127_1690456_10 depolymerase - - - 0.00000000000000000000000000000000000007045 156.0
TH2_k127_1690456_11 PFAM Mo-dependent nitrogenase - - - 0.00000000000000000000000764 107.0
TH2_k127_1690456_12 SET domain - - - 0.00000000000000000005329 96.0
TH2_k127_1690456_13 - - - - 0.00000000000008035 75.0
TH2_k127_1690456_14 Rdx family K07401 - - 0.000000000002088 70.0
TH2_k127_1690456_15 - - - - 0.00000065 51.0
TH2_k127_1690456_17 Helix-turn-helix XRE-family like proteins - - - 0.0006451 50.0
TH2_k127_1690456_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 381.0
TH2_k127_1690456_3 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 316.0
TH2_k127_1690456_4 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 290.0
TH2_k127_1690456_5 SEC-C Motif Domain Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000343 255.0
TH2_k127_1690456_6 Transcriptional regulator, AbiEi antitoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008115 241.0
TH2_k127_1690456_7 Rhodanese-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001518 232.0
TH2_k127_1690456_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000003735 192.0
TH2_k127_1690456_9 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000003007 167.0
TH2_k127_1741504_0 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 1.02e-304 949.0
TH2_k127_1741504_1 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 415.0
TH2_k127_1741504_2 Methyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001187 279.0
TH2_k127_1741504_3 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000006376 168.0
TH2_k127_1741504_5 Protein of unknown function (DUF3185) - - - 0.0000000000001918 73.0
TH2_k127_1809959_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1158.0
TH2_k127_1809959_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 591.0
TH2_k127_1809959_10 Protein of unknown function (DUF2167) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001476 291.0
TH2_k127_1809959_11 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009459 265.0
TH2_k127_1809959_12 HmuY protein - - - 0.000000000000000000000000000000000000000000000000000000000007187 216.0
TH2_k127_1809959_13 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000001263 207.0
TH2_k127_1809959_14 protease K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000006237 172.0
TH2_k127_1809959_15 PilZ domain - - - 0.0000000000000000000000000000003753 141.0
TH2_k127_1809959_16 AhpC/TSA antioxidant enzyme - - - 0.0000000000000006461 83.0
TH2_k127_1809959_18 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000145 69.0
TH2_k127_1809959_19 DnaJ molecular chaperone homology domain - - - 0.00000000123 66.0
TH2_k127_1809959_2 COG0659 Sulfate permease and related transporters (MFS superfamily) K01673,K03321 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 549.0
TH2_k127_1809959_20 type II secretion system protein E K02652 - - 0.000000009813 66.0
TH2_k127_1809959_21 Domain of unknown function (DUF4178) - - - 0.000001297 57.0
TH2_k127_1809959_3 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 540.0
TH2_k127_1809959_4 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 494.0
TH2_k127_1809959_5 Belongs to the peptidase S8 family K01341,K20755 - 3.4.21.121,3.4.21.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 439.0
TH2_k127_1809959_6 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 379.0
TH2_k127_1809959_7 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 350.0
TH2_k127_1809959_8 Family membership K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 351.0
TH2_k127_1809959_9 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 297.0
TH2_k127_1834929_0 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 569.0
TH2_k127_1834929_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 562.0
TH2_k127_1834929_10 histone H2A K63-linked ubiquitination - - - 0.000000000000000000004677 106.0
TH2_k127_1834929_11 Helix-hairpin-helix motif - - - 0.00000000000000007036 86.0
TH2_k127_1834929_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.000000000000000147 94.0
TH2_k127_1834929_14 Cupin - - - 0.0000004936 61.0
TH2_k127_1834929_15 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000001954 56.0
TH2_k127_1834929_2 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 457.0
TH2_k127_1834929_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 437.0
TH2_k127_1834929_4 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 341.0
TH2_k127_1834929_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004747 274.0
TH2_k127_1834929_6 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000008779 209.0
TH2_k127_1834929_7 Domain of unknown function (4846) - - - 0.0000000000000000000000000000000000000000000000000000003515 203.0
TH2_k127_1834929_8 type II secretion system protein E K02283 - - 0.000000000000000000000000000000000000000000004646 180.0
TH2_k127_1834929_9 EVE domain - - - 0.0000000000000000000000000000000000000000001108 163.0
TH2_k127_1845155_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.996e-200 636.0
TH2_k127_1845155_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 504.0
TH2_k127_1845155_10 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000009387 188.0
TH2_k127_1845155_11 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000002563 169.0
TH2_k127_1845155_12 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000002184 169.0
TH2_k127_1845155_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000009132 141.0
TH2_k127_1845155_14 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000004846 127.0
TH2_k127_1845155_15 - - - - 0.00000000000000002006 94.0
TH2_k127_1845155_16 - - - - 0.00000007804 65.0
TH2_k127_1845155_17 histidine kinase A domain protein - - - 0.000003682 55.0
TH2_k127_1845155_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 511.0
TH2_k127_1845155_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 487.0
TH2_k127_1845155_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 469.0
TH2_k127_1845155_5 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 330.0
TH2_k127_1845155_6 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000193 289.0
TH2_k127_1845155_7 DHH family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001988 280.0
TH2_k127_1845155_8 PFAM ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000004319 264.0
TH2_k127_1845155_9 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000004651 189.0
TH2_k127_1872789_0 PHP domain protein - - - 2.473e-318 1011.0
TH2_k127_1872789_1 Belongs to the ClpA ClpB family K03694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 399.0
TH2_k127_1872789_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 324.0
TH2_k127_1872889_0 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 486.0
TH2_k127_1872889_1 PFAM TonB-dependent Receptor K16091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 467.0
TH2_k127_1872889_2 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 423.0
TH2_k127_1872889_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 420.0
TH2_k127_1872889_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886,K16066 - 1.1.1.276,1.1.1.381 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 362.0
TH2_k127_1872889_5 Homologues of snake disintegrins - - - 0.00000000000000000000000004855 125.0
TH2_k127_1872889_6 energy transducer activity K03646,K03832 - - 0.00000002522 59.0
TH2_k127_1872889_7 Lecithin:cholesterol acyltransferase - - - 0.0004172 53.0
TH2_k127_1898072_0 Tetratricopeptide repeat - - - 0.0 1718.0
TH2_k127_1898072_1 Diguanylate cyclase, GGDEF domain - - - 2.359e-262 848.0
TH2_k127_1898072_2 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 444.0
TH2_k127_1898072_3 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 428.0
TH2_k127_1898072_4 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 392.0
TH2_k127_1898072_5 Permease family K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 354.0
TH2_k127_1898072_6 amino acid activation for nonribosomal peptide biosynthetic process K14379 - 3.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000001558 236.0
TH2_k127_1898072_7 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000001439 158.0
TH2_k127_1898072_8 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000913 165.0
TH2_k127_1898072_9 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.0000000000000000000000000001483 134.0
TH2_k127_1913303_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 483.0
TH2_k127_1913303_1 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 478.0
TH2_k127_1913303_10 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.000000571 61.0
TH2_k127_1913303_11 TPR repeat - - - 0.00002829 53.0
TH2_k127_1913303_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 424.0
TH2_k127_1913303_3 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 405.0
TH2_k127_1913303_4 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000009923 247.0
TH2_k127_1913303_5 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000002031 228.0
TH2_k127_1913303_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000247 129.0
TH2_k127_1913303_7 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000003027 103.0
TH2_k127_1913303_8 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.0000000000001469 85.0
TH2_k127_1913303_9 Tetratricopeptide repeat - - - 0.000000002422 69.0
TH2_k127_193265_0 DNA polymerase K02337,K14162 GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0 1333.0
TH2_k127_193265_1 impB/mucB/samB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 329.0
TH2_k127_193265_2 Voltage gated chloride channel - - - 0.0000000000000000000000000000000000000004986 153.0
TH2_k127_193265_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.0000000000000000000000000000000000000009405 156.0
TH2_k127_1933903_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.019e-257 810.0
TH2_k127_1933903_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 539.0
TH2_k127_1933903_2 Hsp70 protein K04046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 471.0
TH2_k127_1933903_3 Transcription elongation factor, GreA/GreB, C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000006972 226.0
TH2_k127_1933903_4 methyltransferase K00590,K07319 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000001119 219.0
TH2_k127_1933903_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000008708 181.0
TH2_k127_1933903_6 HAD-hyrolase-like K01091,K16017 - 3.1.3.18 0.00000000000000000000000006464 125.0
TH2_k127_1934040_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 483.0
TH2_k127_1934040_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 347.0
TH2_k127_1934040_2 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 297.0
TH2_k127_1934040_3 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000006625 223.0
TH2_k127_1934040_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000001691 184.0
TH2_k127_1934040_5 GGDEF domain K21009 - - 0.0000000000000000000007853 106.0
TH2_k127_1934040_8 domain, Protein K20276 - - 0.0003556 52.0
TH2_k127_1934040_9 Histidine kinase K07679 - 2.7.13.3 0.0006026 52.0
TH2_k127_1961661_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 1.702e-214 679.0
TH2_k127_1961661_1 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 3.954e-198 631.0
TH2_k127_1961661_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 476.0
TH2_k127_1961661_3 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 364.0
TH2_k127_1961661_4 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 297.0
TH2_k127_1961661_5 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001587 286.0
TH2_k127_1961661_6 protein tyrosine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001886 238.0
TH2_k127_1961661_7 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000003233 216.0
TH2_k127_1961661_8 extracellular polysaccharide biosynthetic process K03497,K07011,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000003304 92.0
TH2_k127_1961661_9 protein homooligomerization K21919 - - 0.0000000003067 70.0
TH2_k127_1972547_0 sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 610.0
TH2_k127_1972547_1 proteolysis - - - 0.0000000000000000000000001172 117.0
TH2_k127_1979560_0 Glycine radical K00656,K07540,K20038 - 2.3.1.54,4.1.99.11,4.3.99.4 8.176e-199 640.0
TH2_k127_1979560_1 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001159 259.0
TH2_k127_198053_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 5.2e-219 698.0
TH2_k127_198053_1 pathogenesis K00631,K01897 - 2.3.1.15,6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 629.0
TH2_k127_198053_2 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000469 265.0
TH2_k127_198053_3 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000001247 242.0
TH2_k127_198053_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000002126 183.0
TH2_k127_198053_5 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000003184 140.0
TH2_k127_198053_6 PFAM Binding-protein-dependent transport K02033 - - 0.00000000000000000000000000003464 128.0
TH2_k127_2001316_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 7.464e-218 683.0
TH2_k127_2001316_1 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 569.0
TH2_k127_2040261_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 587.0
TH2_k127_2040261_1 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 505.0
TH2_k127_2040261_10 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000001181 95.0
TH2_k127_2040261_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K02022,K03585 - - 0.00000001166 68.0
TH2_k127_2040261_2 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 518.0
TH2_k127_2040261_3 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 370.0
TH2_k127_2040261_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 394.0
TH2_k127_2040261_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 337.0
TH2_k127_2040261_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001864 261.0
TH2_k127_2040261_7 Methyltransferase domain K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000001494 226.0
TH2_k127_2040261_8 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000000003066 204.0
TH2_k127_2040261_9 - - - - 0.000000000000000000000000000000000001759 144.0
TH2_k127_2042893_0 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002934 282.0
TH2_k127_2042893_1 ABC transporter K01990,K21397 - - 0.00000000006892 74.0
TH2_k127_2070708_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000001813 198.0
TH2_k127_2070708_1 Metal dependent phosphohydrolase - - - 0.000000000000000000000000000003187 129.0
TH2_k127_2070708_2 Transposase IS4 family protein - - - 0.0003133 43.0
TH2_k127_2079052_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 344.0
TH2_k127_2079052_1 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 308.0
TH2_k127_2079052_10 PFAM Glycosyl transferase family 2 - - - 0.0000115 58.0
TH2_k127_2079052_11 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 2.7.7.60 0.0001304 51.0
TH2_k127_2079052_2 2 iron, 2 sulfur cluster binding K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000002193 206.0
TH2_k127_2079052_3 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000001061 179.0
TH2_k127_2079052_4 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.00000000000000000000000000000000005485 142.0
TH2_k127_2079052_5 Subtilase family - - - 0.0000000000000000000000000000001953 133.0
TH2_k127_2079052_6 WYL domain - - - 0.000000000000000000000000000005222 132.0
TH2_k127_2079052_7 DoxX-like family - - - 0.000000000000000000000000000006277 127.0
TH2_k127_2079052_8 Belongs to the bacterial histone-like protein family - - - 0.000000000000000000000000001194 115.0
TH2_k127_2079052_9 ADP-ribosylglycohydrolase - - - 0.000000000000000000001604 108.0
TH2_k127_217051_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.357e-263 826.0
TH2_k127_217051_1 Molecular chaperone. Has ATPase activity K04079 - - 7.3e-236 773.0
TH2_k127_217051_10 Carbon-nitrogen hydrolase K01431,K12251 - 3.5.1.53,3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 478.0
TH2_k127_217051_11 Belongs to the aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 483.0
TH2_k127_217051_12 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 428.0
TH2_k127_217051_13 methyltransferase activity K00213,K00222 - 1.3.1.21,1.3.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 409.0
TH2_k127_217051_14 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 385.0
TH2_k127_217051_15 Pyridine nucleotide-disulphide oxidoreductase K00266,K00528,K17722 - 1.18.1.2,1.19.1.1,1.3.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 372.0
TH2_k127_217051_16 A G-specific K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 306.0
TH2_k127_217051_17 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009825 286.0
TH2_k127_217051_18 regulation of response to stimulus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002867 278.0
TH2_k127_217051_19 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008119 267.0
TH2_k127_217051_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.81e-214 683.0
TH2_k127_217051_20 short-chain dehydrogenase K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002146 254.0
TH2_k127_217051_21 SMART serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000007771 250.0
TH2_k127_217051_22 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000001657 230.0
TH2_k127_217051_23 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000447 239.0
TH2_k127_217051_24 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000003997 225.0
TH2_k127_217051_25 Bacterioferritin K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000002552 217.0
TH2_k127_217051_26 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000008333 200.0
TH2_k127_217051_27 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000344 184.0
TH2_k127_217051_28 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000001572 149.0
TH2_k127_217051_29 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.00000000000000000000000000000148 141.0
TH2_k127_217051_3 TIGRFAM Dihydroorotate dehydrogenase K17723 - 1.3.1.1 7.439e-199 627.0
TH2_k127_217051_30 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000007922 136.0
TH2_k127_217051_31 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000004546 118.0
TH2_k127_217051_32 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000001453 106.0
TH2_k127_217051_34 protein conserved in bacteria - - - 0.00000000000000000000357 98.0
TH2_k127_217051_35 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000006586 102.0
TH2_k127_217051_36 peptidyl-tyrosine sulfation - - - 0.00000000000000000003676 104.0
TH2_k127_217051_38 MMPL family - - - 0.0000000000000003644 93.0
TH2_k127_217051_39 - - - - 0.000000000000001445 92.0
TH2_k127_217051_4 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 611.0
TH2_k127_217051_40 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000009883 78.0
TH2_k127_217051_41 lactoylglutathione lyase activity - - - 0.0000000003953 66.0
TH2_k127_217051_42 Protein of unknown function (DUF1328) - - - 0.0000000007278 64.0
TH2_k127_217051_43 chitin binding - - - 0.0000007013 62.0
TH2_k127_217051_44 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0001807 54.0
TH2_k127_217051_45 GtrA-like protein K00995 - 2.7.8.5 0.0004832 49.0
TH2_k127_217051_5 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 600.0
TH2_k127_217051_6 PFAM amidohydrolase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 595.0
TH2_k127_217051_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 589.0
TH2_k127_217051_8 Bacterial regulatory protein, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 516.0
TH2_k127_217051_9 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase K00322 - 1.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 495.0
TH2_k127_218299_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 410.0
TH2_k127_218299_1 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 302.0
TH2_k127_218299_2 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002814 258.0
TH2_k127_218299_3 PFAM Integrase, catalytic core - - - 0.000000000000000000000000000000000000000000000000000000000000000007134 230.0
TH2_k127_218299_4 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000003977 215.0
TH2_k127_218299_5 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000002857 185.0
TH2_k127_218299_6 Transposase - - - 0.00000000000000000000000000000002574 128.0
TH2_k127_218299_7 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000004825 64.0
TH2_k127_2219232_0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 336.0
TH2_k127_2219232_1 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000004057 215.0
TH2_k127_2233885_0 Cytochrome c-type biogenesis protein K02198 - - 1.864e-241 773.0
TH2_k127_2233885_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 4.951e-231 735.0
TH2_k127_2233885_10 - - - - 0.00000000000000000000000000000000000000000000000000000000002279 224.0
TH2_k127_2233885_11 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000003889 206.0
TH2_k127_2233885_12 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000009372 205.0
TH2_k127_2233885_13 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000368 203.0
TH2_k127_2233885_14 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000468 196.0
TH2_k127_2233885_15 GGDEF domain - - - 0.0000000000000000000000000000000000000000000007411 177.0
TH2_k127_2233885_16 energy transducer activity K02487,K03832,K06596 - - 0.000000000000000000000000000000001835 136.0
TH2_k127_2233885_17 - - - - 0.0000000000000000000000000003532 124.0
TH2_k127_2233885_18 - - - - 0.000000000000000003019 93.0
TH2_k127_2233885_2 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 533.0
TH2_k127_2233885_20 Stringent starvation protein B K03600 - - 0.00000000000000003751 89.0
TH2_k127_2233885_21 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000174 86.0
TH2_k127_2233885_23 TPR repeat - - - 0.000003473 57.0
TH2_k127_2233885_3 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 499.0
TH2_k127_2233885_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 461.0
TH2_k127_2233885_5 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 451.0
TH2_k127_2233885_6 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 383.0
TH2_k127_2233885_7 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 353.0
TH2_k127_2233885_8 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 337.0
TH2_k127_2233885_9 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000009032 280.0
TH2_k127_2244698_0 prohibitin homologues K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 379.0
TH2_k127_2244698_1 prohibitin homologues K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006652 294.0
TH2_k127_2244698_2 - - - - 0.000000000000002193 84.0
TH2_k127_2261005_0 Lamin Tail Domain - - - 3.098e-205 671.0
TH2_k127_2261005_1 lytic transglycosylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 300.0
TH2_k127_2261005_2 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000002241 202.0
TH2_k127_2261005_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000001414 162.0
TH2_k127_2300931_0 helicase superfamily c-terminal domain - - - 6.361e-283 906.0
TH2_k127_2300931_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 410.0
TH2_k127_2300931_10 diguanylate cyclase - - - 0.0000000000000000000000000000000000139 151.0
TH2_k127_2300931_11 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000006824 126.0
TH2_k127_2300931_12 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000001846 124.0
TH2_k127_2300931_13 - - - - 0.0000000000000000000000000002506 125.0
TH2_k127_2300931_14 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000000004653 113.0
TH2_k127_2300931_15 - - - - 0.000000000000000000000000005006 120.0
TH2_k127_2300931_16 FecR protein - - - 0.00000000000000000000007034 108.0
TH2_k127_2300931_17 Two component regulator propeller - - - 0.0000000000000000000003334 105.0
TH2_k127_2300931_18 Protein of unknown function (DUF433) - - - 0.00000000000000000001975 92.0
TH2_k127_2300931_19 ROK family - - - 0.00000000000000000003385 94.0
TH2_k127_2300931_2 SMART Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 331.0
TH2_k127_2300931_20 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000005629 95.0
TH2_k127_2300931_21 RHS Repeat - - - 0.000000000000000003913 95.0
TH2_k127_2300931_22 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000009449 94.0
TH2_k127_2300931_23 - - - - 0.00000000000000004101 91.0
TH2_k127_2300931_24 EXOIII K02342 - 2.7.7.7 0.000000000000004344 86.0
TH2_k127_2300931_25 DNA replication, synthesis of RNA primer K04066 - - 0.00000000000001853 87.0
TH2_k127_2300931_26 amine dehydrogenase activity - - - 0.00000000001813 76.0
TH2_k127_2300931_27 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000001183 72.0
TH2_k127_2300931_28 Hep Hag repeat protein - - - 0.0000000007239 71.0
TH2_k127_2300931_3 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 307.0
TH2_k127_2300931_30 Transposase - - - 0.00008191 48.0
TH2_k127_2300931_31 - - - - 0.0004293 44.0
TH2_k127_2300931_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002108 251.0
TH2_k127_2300931_5 - - - - 0.00000000000000000000000000000000000000000000000000000000002488 218.0
TH2_k127_2300931_6 - - - - 0.000000000000000000000000000000000000009608 148.0
TH2_k127_2300931_7 OmpA family K03286 - - 0.00000000000000000000000000000000000006113 165.0
TH2_k127_2300931_8 - - - - 0.0000000000000000000000000000000000002038 157.0
TH2_k127_2300931_9 Belongs to the UPF0225 family K09858 - - 0.000000000000000000000000000000000000768 145.0
TH2_k127_2329170_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 462.0
TH2_k127_2329170_1 Kelch motif - - - 0.0000000000000479 86.0
TH2_k127_2329170_2 Cytochrome b subunit of the bc complex K00412 - - 0.00006763 47.0
TH2_k127_2336342_0 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 527.0
TH2_k127_2336342_1 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 346.0
TH2_k127_2336342_2 nitrile biosynthetic process - - - 0.0000000005318 70.0
TH2_k127_2345222_0 Belongs to the MurCDEF family K03802 - 6.3.2.29,6.3.2.30 3.646e-298 944.0
TH2_k127_2345222_1 cyanophycin K03802 - 6.3.2.29,6.3.2.30 2.331e-294 927.0
TH2_k127_2345222_2 ABC transporter transmembrane region K06147 - - 2.918e-248 788.0
TH2_k127_2345222_3 ABC transporter domain protein K02471 - - 1.115e-244 767.0
TH2_k127_2345222_4 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 357.0
TH2_k127_2345222_5 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002111 286.0
TH2_k127_2345222_6 Domain of unknown function (DUF1854) - - - 0.00000000000000000000000000000003343 132.0
TH2_k127_2349951_0 Elongator protein 3, MiaB family, Radical SAM - - - 1.286e-252 803.0
TH2_k127_2349951_1 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000000000006657 216.0
TH2_k127_2349951_2 rRNA processing K06968 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.186 0.00000000000000000000000000000001496 134.0
TH2_k127_2352834_0 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 468.0
TH2_k127_2352834_1 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000001377 227.0
TH2_k127_2356195_0 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 603.0
TH2_k127_2356195_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 480.0
TH2_k127_2356195_10 - - - - 0.0000000000000000000000000000000000007115 141.0
TH2_k127_2356195_11 - - - - 0.000000000000000000000000000000000007821 140.0
TH2_k127_2356195_12 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000001745 143.0
TH2_k127_2356195_13 COG NOG15344 non supervised orthologous group - - - 0.000000000000000000000000002388 112.0
TH2_k127_2356195_14 - - - - 0.00000000000000000000003689 99.0
TH2_k127_2356195_16 - - - - 0.00000000000000000001411 96.0
TH2_k127_2356195_18 - - - - 0.0000000000000000003111 88.0
TH2_k127_2356195_19 LysM domain - - - 0.000000000000000002326 100.0
TH2_k127_2356195_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 440.0
TH2_k127_2356195_20 the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts - - - 0.0000000000000002271 83.0
TH2_k127_2356195_21 - - - - 0.000000000000002971 76.0
TH2_k127_2356195_22 ORF located using Blastx - - - 0.0000000000004469 69.0
TH2_k127_2356195_23 - - - - 0.0000000000005997 73.0
TH2_k127_2356195_25 - - - - 0.00000000003117 63.0
TH2_k127_2356195_26 - - - - 0.0000000002799 64.0
TH2_k127_2356195_27 COG NOG14552 non supervised orthologous group - - - 0.0000000004168 60.0
TH2_k127_2356195_28 TPR Domain containing protein K12600 - - 0.00000003567 66.0
TH2_k127_2356195_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 428.0
TH2_k127_2356195_31 - - - - 0.000002304 49.0
TH2_k127_2356195_33 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00001215 55.0
TH2_k127_2356195_34 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00001237 55.0
TH2_k127_2356195_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 413.0
TH2_k127_2356195_5 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 443.0
TH2_k127_2356195_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 355.0
TH2_k127_2356195_7 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000004989 219.0
TH2_k127_2356195_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000006308 201.0
TH2_k127_2356195_9 - - - - 0.0000000000000000000000000000000000000000001364 161.0
TH2_k127_2361209_0 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 595.0
TH2_k127_2361209_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000003579 227.0
TH2_k127_2361209_2 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000009803 183.0
TH2_k127_2361209_3 - - - - 0.0000000000000000000000000000005988 132.0
TH2_k127_2361209_4 Fe-S-cluster oxidoreductase K06940 - - 0.0000000000000000000000000003697 127.0
TH2_k127_2361209_5 Cold shock protein K03704 - - 0.00000000000000000000000004027 111.0
TH2_k127_2361209_6 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000001549 99.0
TH2_k127_2361209_7 signal transduction protein with CBS domains - - - 0.0000008491 61.0
TH2_k127_2361209_8 PEGA domain - - - 0.00003483 55.0
TH2_k127_2361209_9 Stigma-specific protein, Stig1 - - - 0.0009671 50.0
TH2_k127_2378897_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 420.0
TH2_k127_2378897_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000277 267.0
TH2_k127_2378897_2 Glycine cleavage H-protein - - - 0.00000000000000000001535 94.0
TH2_k127_2378973_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 364.0
TH2_k127_2404008_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 406.0
TH2_k127_2404008_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000913 301.0
TH2_k127_2404008_2 von Willebrand factor (vWF) type A domain - - - 0.00000000003138 75.0
TH2_k127_2422306_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 353.0
TH2_k127_2422306_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008092 268.0
TH2_k127_2422306_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000003329 222.0
TH2_k127_2422306_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0005575,GO:0005576,GO:0008150,GO:0009605,GO:0009607,GO:0031347,GO:0031348,GO:0035821,GO:0040007,GO:0043207,GO:0044003,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0075136,GO:0080134 4.6.1.17 0.00000000000000000000000000000000000000004853 167.0
TH2_k127_2422306_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000002504 104.0
TH2_k127_2422306_5 Protein conserved in bacteria - - - 0.00000000000000004372 90.0
TH2_k127_2422306_6 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000953 60.0
TH2_k127_2439026_0 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 513.0
TH2_k127_2439026_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008169 237.0
TH2_k127_2439026_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000005571 129.0
TH2_k127_2439026_3 PQQ-like domain - - - 0.00013 51.0
TH2_k127_2456443_0 Belongs to the UPF0229 family K09786 - - 1.144e-194 612.0
TH2_k127_2456443_1 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 470.0
TH2_k127_2456443_12 glycerophosphoinositol glycerophosphodiesterase activity K01126,K19179 GO:0000902,GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006066,GO:0006576,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007186,GO:0007275,GO:0007399,GO:0008081,GO:0008150,GO:0008152,GO:0008889,GO:0009056,GO:0009308,GO:0009395,GO:0009653,GO:0009987,GO:0016020,GO:0016021,GO:0016042,GO:0016043,GO:0016298,GO:0016787,GO:0016788,GO:0019637,GO:0022008,GO:0023052,GO:0030030,GO:0030154,GO:0030182,GO:0031175,GO:0031224,GO:0031226,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0034308,GO:0034641,GO:0042439,GO:0042578,GO:0044106,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046434,GO:0046475,GO:0046486,GO:0046503,GO:0047395,GO:0048468,GO:0048666,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052689,GO:0065007,GO:0070291,GO:0071704,GO:0071840,GO:0071944,GO:0120036,GO:0120039,GO:1901564,GO:1901575,GO:1901615 3.1.4.44,3.1.4.46 0.00002728 55.0
TH2_k127_2456443_2 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 407.0
TH2_k127_2456443_3 SpoVR like protein K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 393.0
TH2_k127_2456443_4 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 351.0
TH2_k127_2456443_5 PFAM Inward rectifier potassium channel K08715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 290.0
TH2_k127_2456443_6 Putative neutral zinc metallopeptidase K06973 - - 0.0000000000000000000000000000000000000000000000000000006522 214.0
TH2_k127_2456443_7 Protein of unknown function (DUF3224) - - - 0.00000000000000000000000000000000000000000001014 173.0
TH2_k127_2456443_8 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000004578 145.0
TH2_k127_2456443_9 Bacterial protein of unknown function (YtfJ_HI0045) K07109 - - 0.000000000000000002048 91.0
TH2_k127_246213_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 444.0
TH2_k127_246213_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 384.0
TH2_k127_246213_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 332.0
TH2_k127_246213_3 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 306.0
TH2_k127_246213_4 Rieske [2Fe-2S] domain K09879 - - 0.00000000000000000007599 94.0
TH2_k127_246213_5 Protein conserved in bacteria - - - 0.0000000001397 64.0
TH2_k127_246213_6 TPR repeat - - - 0.000000414 58.0
TH2_k127_2467411_0 protein involved in exopolysaccharide biosynthesis K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 403.0
TH2_k127_2467411_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 335.0
TH2_k127_2467411_2 DegT/DnrJ/EryC1/StrS aminotransferase family K02805,K07806 - 2.6.1.59,2.6.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 331.0
TH2_k127_2467411_3 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase K07257 - - 0.000000000000000000000000000001688 138.0
TH2_k127_2473088_0 Cytochrome P450 K05917 - 1.14.13.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 470.0
TH2_k127_2473088_1 zinc ion binding K06204 - - 0.000000000000000000000000000000000000122 148.0
TH2_k127_2473088_2 cheY-homologous receiver domain - - - 0.000000000000000000444 93.0
TH2_k127_2473088_3 AefR-like transcriptional repressor, C-terminal region - - - 0.00002366 50.0
TH2_k127_2502121_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 6.151e-258 809.0
TH2_k127_2502121_1 Peptidase S46 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 625.0
TH2_k127_2502121_2 Periplasmic protein TonB links inner and outer membranes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 572.0
TH2_k127_2502121_3 PFAM hydroxyneurosporene synthase K09844 - 4.2.1.131 0.000000000000000000000000000000000000000004456 177.0
TH2_k127_2502205_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000002974 230.0
TH2_k127_2502205_1 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000001983 220.0
TH2_k127_2502205_2 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000003992 169.0
TH2_k127_2502205_3 - - - - 0.0000000000000000000000000003822 122.0
TH2_k127_2502205_5 lipid kinase activity - - - 0.0000000001622 72.0
TH2_k127_2502205_6 Protein tyrosine kinase - - - 0.00005239 56.0
TH2_k127_2503305_0 PFAM Glycoside hydrolase 15-related - - - 2.239e-239 758.0
TH2_k127_2503305_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.826e-204 649.0
TH2_k127_2503305_12 PFAM Glucose-6-phosphate dehydrogenase subunit - - - 0.00001864 57.0
TH2_k127_2503305_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 427.0
TH2_k127_2503305_3 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 327.0
TH2_k127_2503305_4 vancomycin resistance protein K18346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004771 278.0
TH2_k127_2503305_5 Squalene epoxidase K00511 - 1.14.14.17 0.00000000000000000000000000000000000000000000000000000000000000000000000002969 267.0
TH2_k127_2503305_6 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000005729 239.0
TH2_k127_2503305_7 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000001565 196.0
TH2_k127_2503305_8 Glycosyl hydrolases family 15 K07190 - - 0.000000000000000000000000000000000000000000002588 189.0
TH2_k127_2503305_9 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000001542 156.0
TH2_k127_2504993_0 PrkA AAA domain K07180 - - 0.0 1118.0
TH2_k127_2504993_1 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 329.0
TH2_k127_2504993_2 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000000003491 135.0
TH2_k127_2504993_3 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.00000000000000002013 95.0
TH2_k127_2510504_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 3.217e-269 843.0
TH2_k127_2510504_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 524.0
TH2_k127_2520173_0 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 502.0
TH2_k127_2520173_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 329.0
TH2_k127_2520173_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 308.0
TH2_k127_2520173_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000008571 164.0
TH2_k127_2520173_4 Acyltransferase - - - 0.0000000000000000000000000000003545 127.0
TH2_k127_2545670_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 461.0
TH2_k127_2545670_1 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 448.0
TH2_k127_2545670_2 Holliday junction DNA helicase ruvB N-terminus K13525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 445.0
TH2_k127_2545670_3 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 342.0
TH2_k127_2545670_4 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000001297 250.0
TH2_k127_2545670_5 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000001631 117.0
TH2_k127_255233_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007121 284.0
TH2_k127_255233_1 - - - - 0.000000000000000000000000000000000000000000002632 175.0
TH2_k127_255233_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000003522 83.0
TH2_k127_2567660_0 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 579.0
TH2_k127_2567660_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 545.0
TH2_k127_2567660_10 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 335.0
TH2_k127_2567660_11 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 344.0
TH2_k127_2567660_12 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 317.0
TH2_k127_2567660_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 316.0
TH2_k127_2567660_14 polysaccharide biosynthetic process K06409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 307.0
TH2_k127_2567660_15 Von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 289.0
TH2_k127_2567660_16 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006939 295.0
TH2_k127_2567660_17 Belongs to the ompA family K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005503 278.0
TH2_k127_2567660_18 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000003304 254.0
TH2_k127_2567660_19 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000005487 259.0
TH2_k127_2567660_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 521.0
TH2_k127_2567660_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003578 239.0
TH2_k127_2567660_21 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000000000000000007681 185.0
TH2_k127_2567660_22 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000001835 181.0
TH2_k127_2567660_23 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000005469 166.0
TH2_k127_2567660_24 PFAM methyltransferase K15460 - 2.1.1.223 0.00000000000000000000000000000000000001303 160.0
TH2_k127_2567660_25 zinc ion binding K06204 - - 0.000000000000000000000000000000501 127.0
TH2_k127_2567660_26 peptidyl-tyrosine sulfation - - - 0.0000000000000000008189 103.0
TH2_k127_2567660_28 Carboxypeptidase regulatory-like domain - - - 0.0000000000461 76.0
TH2_k127_2567660_29 Tetratricopeptide repeat - - - 0.00000000098 73.0
TH2_k127_2567660_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 474.0
TH2_k127_2567660_30 Protein of unknown function (DUF3108) - - - 0.0000000122 66.0
TH2_k127_2567660_31 type IV pilus biogenesis stability protein PilW K02656 - - 0.0003044 55.0
TH2_k127_2567660_4 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 465.0
TH2_k127_2567660_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 431.0
TH2_k127_2567660_6 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 419.0
TH2_k127_2567660_7 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 417.0
TH2_k127_2567660_8 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 399.0
TH2_k127_2567660_9 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 364.0
TH2_k127_2569002_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 518.0
TH2_k127_2569002_1 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 422.0
TH2_k127_2569002_10 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000005925 224.0
TH2_k127_2569002_11 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000007345 202.0
TH2_k127_2569002_12 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000007289 98.0
TH2_k127_2569002_13 - - - - 0.00000000000000002096 94.0
TH2_k127_2569002_14 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000000039 66.0
TH2_k127_2569002_16 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000002231 66.0
TH2_k127_2569002_2 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 404.0
TH2_k127_2569002_3 Serine/threonine phosphatases, family 2C, catalytic domain K01090 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 386.0
TH2_k127_2569002_4 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 377.0
TH2_k127_2569002_5 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 366.0
TH2_k127_2569002_6 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 332.0
TH2_k127_2569002_7 Iron permease FTR1 family K07243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 343.0
TH2_k127_2569002_8 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004288 284.0
TH2_k127_2569002_9 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000065 235.0
TH2_k127_2583408_0 Acyl transferase domain - - - 0.0 1202.0
TH2_k127_2583408_1 TIGRFAM PfaD family protein - - - 5.751e-197 629.0
TH2_k127_2583408_2 - - - - 0.000005543 51.0
TH2_k127_2583743_0 dehydrogenase e1 component K00164 - 1.2.4.2 3.367e-306 965.0
TH2_k127_2583743_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 1.047e-240 755.0
TH2_k127_2583743_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 9.642e-218 686.0
TH2_k127_2583743_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000001853 118.0
TH2_k127_2583743_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000004086 105.0
TH2_k127_2583743_5 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000003522 86.0
TH2_k127_2583743_6 Cytochrome c K01256 - 3.4.11.2 0.00000000000001875 78.0
TH2_k127_2589822_0 transferase hexapeptide K02617,K03321 - - 3.781e-225 719.0
TH2_k127_2589822_1 Squalene cyclase K01852 - 5.4.99.7 4.358e-215 691.0
TH2_k127_2589822_10 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 299.0
TH2_k127_2589822_11 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002069 304.0
TH2_k127_2589822_12 Adventurous gliding motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007108 275.0
TH2_k127_2589822_13 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000001753 217.0
TH2_k127_2589822_14 iron ion binding - - - 0.0000000000000000000000000000000000000008406 157.0
TH2_k127_2589822_15 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000004502 130.0
TH2_k127_2589822_16 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000001069 117.0
TH2_k127_2589822_17 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000006857 120.0
TH2_k127_2589822_18 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000003989 110.0
TH2_k127_2589822_2 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 581.0
TH2_k127_2589822_3 In Escherichia coli this enzyme appears to be an NAD NADP -dependent succinate semialdehyde dehydrogenase K00135,K08324 - 1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 563.0
TH2_k127_2589822_4 Belongs to the GMC oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 471.0
TH2_k127_2589822_5 Ergosterol biosynthesis ERG4/ERG24 family K00213,K00223 - 1.3.1.21,1.3.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 348.0
TH2_k127_2589822_6 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 343.0
TH2_k127_2589822_7 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 346.0
TH2_k127_2589822_8 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 339.0
TH2_k127_2589822_9 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 319.0
TH2_k127_2594611_0 Fungalysin metallopeptidase (M36) - - - 4.27e-233 760.0
TH2_k127_2594611_1 synthase K01858 - 5.5.1.4 3.221e-206 649.0
TH2_k127_2594611_10 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000458 286.0
TH2_k127_2594611_11 PFAM Hemolysin-type calcium-binding K01406 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000001902 295.0
TH2_k127_2594611_12 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001925 262.0
TH2_k127_2594611_13 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000153 250.0
TH2_k127_2594611_14 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000002649 219.0
TH2_k127_2594611_15 PFAM alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000001871 223.0
TH2_k127_2594611_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000539 216.0
TH2_k127_2594611_17 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000003021 197.0
TH2_k127_2594611_18 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000002205 203.0
TH2_k127_2594611_19 cellulose binding - - - 0.0000000000000000000000000000000000000000000007469 184.0
TH2_k127_2594611_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 501.0
TH2_k127_2594611_20 Putative zinc-finger - - - 0.00000000000000000000000000000103 134.0
TH2_k127_2594611_22 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000009192 74.0
TH2_k127_2594611_25 extracellular matrix structural constituent - - - 0.00000000000108 82.0
TH2_k127_2594611_26 TPR repeat - - - 0.000000395 61.0
TH2_k127_2594611_27 response regulator - - - 0.000006883 58.0
TH2_k127_2594611_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 432.0
TH2_k127_2594611_4 RmlD substrate binding domain K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 411.0
TH2_k127_2594611_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 357.0
TH2_k127_2594611_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 349.0
TH2_k127_2594611_7 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 350.0
TH2_k127_2594611_8 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 313.0
TH2_k127_2594611_9 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 324.0
TH2_k127_2665749_0 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000001302 203.0
TH2_k127_2665749_1 - - - - 0.000000000000000000000000000000000000000000002334 178.0
TH2_k127_2665749_2 - - - - 0.0000000000000000000000000000000000000116 157.0
TH2_k127_2665749_3 phosphatase activity K07025,K20866 - 3.1.3.10 0.00000000000000000000000005344 116.0
TH2_k127_2665749_4 enzyme binding K00567,K07443 - 2.1.1.63 0.00000000000000000000003391 103.0
TH2_k127_2676800_1 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000663 120.0
TH2_k127_2676800_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000008111 53.0
TH2_k127_268545_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 6.389e-277 878.0
TH2_k127_268545_1 Translation-initiation factor 2 K02519 - - 1.691e-216 696.0
TH2_k127_268545_10 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000006346 107.0
TH2_k127_268545_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000007812 84.0
TH2_k127_268545_12 Protein of unknown function (DUF503) K09764 - - 0.000000000003263 75.0
TH2_k127_268545_13 Electron transfer flavoprotein domain K03521 - - 0.000000003769 67.0
TH2_k127_268545_14 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.00000003453 64.0
TH2_k127_268545_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000006092 246.0
TH2_k127_268545_3 Dehydrogenase reductase K00046,K00065,K20900 GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0030246,GO:0042221,GO:0044238,GO:0047880,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 1.1.1.127,1.1.1.403,1.1.1.69 0.000000000000000000000000000000000000000000000000000000000827 209.0
TH2_k127_268545_4 Protein of unknown function (DUF507) K09804 - - 0.00000000000000000000000000000000000000000000000000003282 192.0
TH2_k127_268545_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000001433 193.0
TH2_k127_268545_6 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000004228 205.0
TH2_k127_268545_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000009825 138.0
TH2_k127_268545_8 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000006771 130.0
TH2_k127_268545_9 diguanylate cyclase - - - 0.0000000000000000000002575 108.0
TH2_k127_2695832_0 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 424.0
TH2_k127_2695832_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 370.0
TH2_k127_2695832_2 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000145 137.0
TH2_k127_2704742_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1040.0
TH2_k127_2704742_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003596 271.0
TH2_k127_2704742_2 Isochorismatase family - - - 0.0000000000000000000000000000000000000005412 156.0
TH2_k127_2704742_3 TPR repeat - - - 0.00000000002619 75.0
TH2_k127_2704742_4 cheY-homologous receiver domain - - - 0.0000000003503 66.0
TH2_k127_2704742_5 TPR repeat - - - 0.000000001246 70.0
TH2_k127_2730249_0 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 566.0
TH2_k127_2730249_1 AAA domain (dynein-related subfamily) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 532.0
TH2_k127_2730249_10 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000001519 185.0
TH2_k127_2730249_11 - K07283 - - 0.00000000000000000000000000000000000000000000002287 181.0
TH2_k127_2730249_12 histone H2A K63-linked ubiquitination K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000007459 178.0
TH2_k127_2730249_13 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000004081 153.0
TH2_k127_2730249_14 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000003872 132.0
TH2_k127_2730249_15 - - - - 0.00000003861 65.0
TH2_k127_2730249_16 High confidence in function and specificity - - - 0.000003752 49.0
TH2_k127_2730249_2 protein containing a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 539.0
TH2_k127_2730249_3 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 406.0
TH2_k127_2730249_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 390.0
TH2_k127_2730249_5 Belongs to the ompA family K03286,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 355.0
TH2_k127_2730249_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 314.0
TH2_k127_2730249_7 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000005028 235.0
TH2_k127_2730249_8 - - - - 0.000000000000000000000000000000000000000000000000000000000008098 218.0
TH2_k127_2730249_9 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000005381 201.0
TH2_k127_276840_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 6.404e-205 662.0
TH2_k127_276840_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000001781 259.0
TH2_k127_276840_3 - K07018 - - 0.0000000000000000003997 96.0
TH2_k127_2788720_0 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 2.743e-245 789.0
TH2_k127_2788720_1 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 372.0
TH2_k127_2788720_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001817 274.0
TH2_k127_2788720_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000001568 230.0
TH2_k127_2788720_4 Periplasmic binding protein K01999 - - 0.00000000000000000000000004384 125.0
TH2_k127_2788720_5 EamA-like transporter family K03298 - - 0.00000000001659 71.0
TH2_k127_2788720_6 Lamin Tail Domain - - - 0.00000000001745 74.0
TH2_k127_2788720_7 Bacterial protein of unknown function (DUF882) - - - 0.00000000002044 77.0
TH2_k127_2788720_8 Tetratricopeptide repeat - - - 0.0000001142 63.0
TH2_k127_2788720_9 Low-density lipoprotein receptor domain class A - - - 0.0006907 48.0
TH2_k127_280256_0 AAA domain K01551 - 3.6.3.16 8.236e-247 775.0
TH2_k127_280256_1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 520.0
TH2_k127_280256_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 491.0
TH2_k127_280256_4 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.00000000000000000000000000000000000000000008776 164.0
TH2_k127_2818813_0 Forkhead associated domain - - - 2.232e-214 673.0
TH2_k127_2818813_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002151 290.0
TH2_k127_2818813_2 protein kinase activity - - - 0.0000000000000000000000000000000000000005664 172.0
TH2_k127_2818813_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000002251 103.0
TH2_k127_2818813_4 Right handed beta helix region - - - 0.00000004643 65.0
TH2_k127_2826453_0 GTPase activity K03596 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0006970,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009268,GO:0009409,GO:0009628,GO:0009651,GO:0009987,GO:0010467,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043021,GO:0043023,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.398e-253 797.0
TH2_k127_2826453_1 Glucose / Sorbosone dehydrogenase - - - 5.536e-221 707.0
TH2_k127_2826453_10 Domain of unknown function (DUF4920) - - - 0.00000000000000000000000000181 118.0
TH2_k127_2826453_12 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000042 96.0
TH2_k127_2826453_13 Ribbon-helix-helix domain - - - 0.000000000000000001824 98.0
TH2_k127_2826453_14 Protein of unknown function (DUF3105) - - - 0.0000000000001437 82.0
TH2_k127_2826453_15 phosphorelay sensor kinase activity - - - 0.0000000000005601 75.0
TH2_k127_2826453_16 - - - - 0.00006125 48.0
TH2_k127_2826453_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 437.0
TH2_k127_2826453_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 361.0
TH2_k127_2826453_4 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 335.0
TH2_k127_2826453_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000002789 259.0
TH2_k127_2826453_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000006025 244.0
TH2_k127_2826453_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000000000002276 229.0
TH2_k127_2826453_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000005296 213.0
TH2_k127_2826453_9 repeat protein - - - 0.00000000000000000000000000000000000001131 155.0
TH2_k127_2830127_0 Bacterial protein of unknown function (DUF885) - - - 1.617e-201 644.0
TH2_k127_2830127_1 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000002271 274.0
TH2_k127_2830127_2 COG0463 Glycosyltransferases involved in cell wall biogenesis K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003921 263.0
TH2_k127_2830127_3 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000001949 167.0
TH2_k127_2830127_4 Protein of unknown function (DUF2505) - - - 0.000000000000000000000000000000005015 138.0
TH2_k127_2830127_5 Methyltransferase domain - - - 0.0000000000000000000008466 104.0
TH2_k127_2830127_6 Cytochrome c K08738 - - 0.00000000000000000001473 100.0
TH2_k127_2830127_7 cytochrome C K08738 - - 0.0000000000000000001264 98.0
TH2_k127_2830127_8 TPR repeat - - - 0.00003968 56.0
TH2_k127_284213_0 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 358.0
TH2_k127_284213_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001206 285.0
TH2_k127_284213_2 PFAM SPFH domain Band 7 family K07192 - - 0.000000000000000003167 90.0
TH2_k127_2853805_0 pfam abc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 480.0
TH2_k127_2853805_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002636 254.0
TH2_k127_2853805_2 PFAM Aldo keto reductase family - - - 0.00000000000000000000000000000000000000000000000000001131 193.0
TH2_k127_2853805_3 SNF2 family N-terminal domain - - - 0.0000000000000000000000001415 121.0
TH2_k127_2867568_0 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003373 250.0
TH2_k127_2867568_2 Flavodoxin - - - 0.0000000000000000000000002646 118.0
TH2_k127_2867568_3 Surface antigen - - - 0.0000000001307 74.0
TH2_k127_2867568_4 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000136 50.0
TH2_k127_2870680_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.744e-309 986.0
TH2_k127_2870680_1 Sigma-54 interaction domain K02584 - - 3.272e-195 631.0
TH2_k127_2870680_2 glutamate--cysteine ligase K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 344.0
TH2_k127_2870680_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000001738 219.0
TH2_k127_2870680_4 phosphorelay signal transduction system - - - 0.0000000000000000000000000000008574 142.0
TH2_k127_2870680_5 Heat shock 70 kDa protein K04043 - - 0.0000000000000000001587 97.0
TH2_k127_2870680_6 - - - - 0.000000000002171 78.0
TH2_k127_2870680_7 - - - - 0.000001259 60.0
TH2_k127_2870680_8 Integral membrane protein CcmA involved in cell shape determination - - - 0.000006315 55.0
TH2_k127_2917531_0 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 445.0
TH2_k127_2917531_1 MgtE intracellular - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007314 289.0
TH2_k127_2919422_0 COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) - - - 0.0 1746.0
TH2_k127_2919422_1 4 iron, 4 sulfur cluster binding - - - 2.81e-199 640.0
TH2_k127_2919422_10 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001066 284.0
TH2_k127_2919422_11 Von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001093 254.0
TH2_k127_2919422_13 Putative RNA methylase family UPF0020 K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000004965 238.0
TH2_k127_2919422_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000002107 231.0
TH2_k127_2919422_15 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000001482 227.0
TH2_k127_2919422_16 Transcriptional regulator, CarD family K07736 - - 0.000000000000000000000000000000000000000000000000000000000001203 214.0
TH2_k127_2919422_17 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000000000000000000000005708 226.0
TH2_k127_2919422_18 (2R)-phospho-3-sulfolactate synthase (ComA) K08097 - 4.4.1.19 0.000000000000000000000000000000000000000000000000000004394 199.0
TH2_k127_2919422_19 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.0000000000000000000000000000000000000000000000000001291 194.0
TH2_k127_2919422_2 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 590.0
TH2_k127_2919422_20 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000003441 189.0
TH2_k127_2919422_21 Belongs to the ComB family K05979 - 3.1.3.71 0.00000000000000000000000000000000006971 143.0
TH2_k127_2919422_23 von Willebrand factor, type A - - - 0.000000000000000000006635 108.0
TH2_k127_2919422_24 Tetratricopeptide repeat - - - 0.000000000000000001334 100.0
TH2_k127_2919422_25 cellulose binding - - - 0.0000000000000002191 94.0
TH2_k127_2919422_26 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000008386 76.0
TH2_k127_2919422_27 - - - - 0.0001216 55.0
TH2_k127_2919422_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 455.0
TH2_k127_2919422_4 VWA domain containing CoxE-like protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 415.0
TH2_k127_2919422_5 Putative glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009325 421.0
TH2_k127_2919422_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 360.0
TH2_k127_2919422_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 342.0
TH2_k127_2919422_8 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 350.0
TH2_k127_2919422_9 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 310.0
TH2_k127_304771_0 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 385.0
TH2_k127_304771_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 340.0
TH2_k127_304771_2 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000159 247.0
TH2_k127_304771_3 PFAM Retinal pigment epithelial membrane protein K00464 - 1.13.11.75 0.0000000000000000000000000000000000000000000006757 185.0
TH2_k127_304771_4 - - - - 0.0000000000000000000004269 101.0
TH2_k127_304771_5 Iron-regulated membrane protein - - - 0.0000000000000000002097 98.0
TH2_k127_304771_6 COG3328 Transposase and inactivated derivatives - - - 0.000000000000212 78.0
TH2_k127_304771_7 - - - - 0.000000000005668 75.0
TH2_k127_304771_8 Transposase IS4 family protein - - - 0.0001071 44.0
TH2_k127_304771_9 Transposase IS66 family K07484 - - 0.0006972 44.0
TH2_k127_304872_0 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 556.0
TH2_k127_304872_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 516.0
TH2_k127_304872_2 SMART serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000008758 281.0
TH2_k127_304872_3 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000004907 210.0
TH2_k127_304872_4 Zinc-dependent metalloprotease - - - 0.00000000000000000000000000000000000000648 164.0
TH2_k127_304872_5 - - - - 0.00000000000000004569 90.0
TH2_k127_304872_6 Transposase IS4 family protein - - - 0.0001071 44.0
TH2_k127_3058648_0 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 619.0
TH2_k127_3058648_1 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 610.0
TH2_k127_3058648_10 Belongs to the BolA IbaG family K05527,K22066 - - 0.000000000000000000000000000001369 123.0
TH2_k127_3058648_11 heme binding K21472 - - 0.000000000000000000000005727 116.0
TH2_k127_3058648_12 Beta-L-arabinofuranosidase, GH127 - - - 0.00000001058 68.0
TH2_k127_3058648_13 - - - - 0.00000001536 63.0
TH2_k127_3058648_2 Zn-dependent proteases and their inactivated homologs K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 571.0
TH2_k127_3058648_3 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 430.0
TH2_k127_3058648_4 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 370.0
TH2_k127_3058648_5 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 353.0
TH2_k127_3058648_6 major facilitator superfamily MFS_1 K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 353.0
TH2_k127_3058648_7 Pfam:Kce - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 321.0
TH2_k127_3058648_8 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000003581 245.0
TH2_k127_3058648_9 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000001374 182.0
TH2_k127_3067820_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 590.0
TH2_k127_3067820_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 384.0
TH2_k127_3067820_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 353.0
TH2_k127_3067820_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000844 204.0
TH2_k127_3067820_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000001162 128.0
TH2_k127_3067820_5 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000008507 76.0
TH2_k127_3099333_0 Fic/DOC family N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 559.0
TH2_k127_3099333_1 Helix-turn-helix type 11 domain protein K13572 - - 0.00000000000000000000000000007349 128.0
TH2_k127_3099333_2 sequence-specific DNA binding - - - 0.000000000000000000000002627 108.0
TH2_k127_3099333_3 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000001048 89.0
TH2_k127_3106777_0 HAMP domain K11383 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 516.0
TH2_k127_3106777_1 Response regulator, receiver K11384 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 434.0
TH2_k127_3106777_2 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000000000005342 116.0
TH2_k127_3119946_0 PFAM peptidase M13 K01415 - 3.4.24.71 2.066e-213 696.0
TH2_k127_3119946_1 FAD dependent oxidoreductase central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 452.0
TH2_k127_3144300_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 310.0
TH2_k127_3144586_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000001333 246.0
TH2_k127_3144586_1 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000152 235.0
TH2_k127_3198283_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 389.0
TH2_k127_3198283_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 391.0
TH2_k127_3198283_10 - - - - 0.000001503 55.0
TH2_k127_3198283_11 Transposase IS116 IS110 IS902 family protein K07486 - - 0.0003245 43.0
TH2_k127_3198283_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 306.0
TH2_k127_3198283_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 301.0
TH2_k127_3198283_4 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005672 276.0
TH2_k127_3198283_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000189 215.0
TH2_k127_3198283_6 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000007963 183.0
TH2_k127_3198283_7 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000003375 88.0
TH2_k127_3198283_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000004188 79.0
TH2_k127_3209537_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 505.0
TH2_k127_3209537_1 Belongs to the peptidase M16 family - - - 0.00000000000008982 75.0
TH2_k127_3226659_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 514.0
TH2_k127_3226659_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 484.0
TH2_k127_3226659_10 synthesis repressor, PhaR - - - 0.0000000000000001153 89.0
TH2_k127_3226659_11 protein heterodimerization activity - - - 0.000000000001869 69.0
TH2_k127_3226659_12 Membrane-associated sensor - - - 0.0001268 53.0
TH2_k127_3226659_2 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 481.0
TH2_k127_3226659_3 Deoxynucleoside kinase K10353 - 2.7.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005541 276.0
TH2_k127_3226659_4 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006888 279.0
TH2_k127_3226659_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006496 253.0
TH2_k127_3226659_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000007556 229.0
TH2_k127_3226659_8 poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 - - 0.000000000000000000000000000000000000000000000000000000005933 213.0
TH2_k127_3226659_9 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000744 127.0
TH2_k127_3236777_0 - - - - 0.000000000000000000000001131 118.0
TH2_k127_3236777_1 23S rRNA-intervening sequence protein - - - 0.0000000226 61.0
TH2_k127_3237133_0 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 462.0
TH2_k127_3237133_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 413.0
TH2_k127_3237133_2 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 351.0
TH2_k127_3237133_3 HPr kinase - - - 0.000000000004628 76.0
TH2_k127_3237133_4 Uncharacterised nucleotidyltransferase - - - 0.000000002505 69.0
TH2_k127_3237133_5 LicD family - - - 0.0000008957 58.0
TH2_k127_3293927_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1116.0
TH2_k127_3293927_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 2.522e-203 661.0
TH2_k127_3293927_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000004434 249.0
TH2_k127_3293927_3 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000003958 229.0
TH2_k127_3293927_4 - - - - 0.0000000000000000000000000000000000000000000000000001562 191.0
TH2_k127_3293927_5 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000004294 104.0
TH2_k127_3293927_6 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000002536 89.0
TH2_k127_3293927_7 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.0000000007929 70.0
TH2_k127_3343669_0 PFAM Integrase catalytic region - - - 1.278e-230 724.0
TH2_k127_3343669_1 IstB-like ATP binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 419.0
TH2_k127_3343669_2 Putative transposase - - - 0.00000000000000000000001474 100.0
TH2_k127_3343669_3 Integrase core domain - - - 0.0006157 42.0
TH2_k127_3357433_0 ABC transporter K03701 - - 0.0 1229.0
TH2_k127_3357433_1 SMART Elongator protein 3 MiaB NifB - - - 2.164e-298 943.0
TH2_k127_3357433_10 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 376.0
TH2_k127_3357433_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 328.0
TH2_k127_3357433_12 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 316.0
TH2_k127_3357433_13 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001202 290.0
TH2_k127_3357433_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004432 273.0
TH2_k127_3357433_15 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000003962 278.0
TH2_k127_3357433_16 Aminotransferase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000001104 263.0
TH2_k127_3357433_17 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000006317 247.0
TH2_k127_3357433_18 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000006496 257.0
TH2_k127_3357433_19 Alpha beta hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000188 241.0
TH2_k127_3357433_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 611.0
TH2_k127_3357433_20 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000007952 218.0
TH2_k127_3357433_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001473 203.0
TH2_k127_3357433_22 PilZ domain - - - 0.0000000000000000000000000000000000000000000000000000006981 199.0
TH2_k127_3357433_23 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000002954 197.0
TH2_k127_3357433_24 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000008555 194.0
TH2_k127_3357433_25 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000238 183.0
TH2_k127_3357433_26 Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde K01737 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000001277 176.0
TH2_k127_3357433_27 cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000000005719 183.0
TH2_k127_3357433_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000001711 168.0
TH2_k127_3357433_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000009486 152.0
TH2_k127_3357433_3 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 586.0
TH2_k127_3357433_30 DNA/RNA non-specific endonuclease K01173 - - 0.000000000000000000000000000000000000003323 160.0
TH2_k127_3357433_31 - - - - 0.00000000000000000000000000000000000008295 163.0
TH2_k127_3357433_32 protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000004976 122.0
TH2_k127_3357433_33 Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000001533 116.0
TH2_k127_3357433_35 transcriptional regulator - - - 0.000000000002035 75.0
TH2_k127_3357433_36 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000006659 66.0
TH2_k127_3357433_37 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate - - - 0.0000002456 62.0
TH2_k127_3357433_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 538.0
TH2_k127_3357433_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 448.0
TH2_k127_3357433_6 Pyruvate dehydrogenase K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 435.0
TH2_k127_3357433_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 386.0
TH2_k127_3357433_8 FAD dependent oxidoreductase K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 389.0
TH2_k127_3357433_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 402.0
TH2_k127_3369529_0 alpha-2-macroglobulin domain protein K06894 - - 0.0 1828.0
TH2_k127_3369529_1 Methionine synthase K00548 - 2.1.1.13 0.0 1380.0
TH2_k127_3369529_10 ArsR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 324.0
TH2_k127_3369529_11 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000008053 280.0
TH2_k127_3369529_12 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002866 267.0
TH2_k127_3369529_13 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000003356 233.0
TH2_k127_3369529_14 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000001274 235.0
TH2_k127_3369529_15 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000002959 219.0
TH2_k127_3369529_16 MerR, DNA binding K19591 - - 0.00000000000000000000000000000000000000004944 158.0
TH2_k127_3369529_17 protein conserved in bacteria - - - 0.0000000000000000000000000000000001257 145.0
TH2_k127_3369529_18 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000008034 123.0
TH2_k127_3369529_19 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000005805 125.0
TH2_k127_3369529_2 penicillin-binding protein K05367 - 2.4.1.129 8.139e-251 796.0
TH2_k127_3369529_20 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 0.000000000000000000005043 99.0
TH2_k127_3369529_22 - - - - 0.0000000000000001856 87.0
TH2_k127_3369529_23 methylamine metabolic process - - - 0.000000000000001085 88.0
TH2_k127_3369529_24 Cytochrome c - - - 0.000000000009227 77.0
TH2_k127_3369529_25 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000764 66.0
TH2_k127_3369529_26 Staphylococcal nuclease homologues - - - 0.000000009282 65.0
TH2_k127_3369529_3 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.079e-202 646.0
TH2_k127_3369529_4 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 1.479e-201 651.0
TH2_k127_3369529_5 Cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 539.0
TH2_k127_3369529_6 ABC transporter transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 554.0
TH2_k127_3369529_7 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 428.0
TH2_k127_3369529_8 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 404.0
TH2_k127_3369529_9 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 368.0
TH2_k127_3377847_0 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 354.0
TH2_k127_3377847_1 Methyltransferase small domain K15460 - 2.1.1.223 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 329.0
TH2_k127_3377847_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000001607 242.0
TH2_k127_3377847_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000002814 179.0
TH2_k127_3377847_4 transcriptional regulator K09017,K22105 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000003141 66.0
TH2_k127_3394696_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 3.459e-202 646.0
TH2_k127_3394696_1 Belongs to the GcvT family K00302,K10815 - 1.4.99.5,1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006885 284.0
TH2_k127_3394696_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000006442 246.0
TH2_k127_3394696_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000005934 191.0
TH2_k127_3421980_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.0 1383.0
TH2_k127_3421980_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1144.0
TH2_k127_3421980_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000001206 135.0
TH2_k127_3421980_11 Small Multidrug Resistance protein K11741 - - 0.00000000000000000000000000004068 119.0
TH2_k127_3421980_13 PilZ domain - - - 0.0000000000000000000000002073 111.0
TH2_k127_3421980_14 protein ubiquitination K10704,K20417,K20656 GO:0000151,GO:0000209,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006082,GO:0006464,GO:0006508,GO:0006511,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009057,GO:0009058,GO:0009507,GO:0009526,GO:0009536,GO:0009628,GO:0009941,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0012505,GO:0016020,GO:0016021,GO:0016053,GO:0016491,GO:0016567,GO:0016705,GO:0016740,GO:0019538,GO:0019637,GO:0019752,GO:0019787,GO:0019899,GO:0019941,GO:0030163,GO:0030433,GO:0031090,GO:0031224,GO:0031371,GO:0031625,GO:0031967,GO:0031969,GO:0031975,GO:0032446,GO:0032787,GO:0032991,GO:0033554,GO:0033559,GO:0034976,GO:0035370,GO:0036211,GO:0036503,GO:0042170,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043436,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044283,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046471,GO:0046486,GO:0050896,GO:0051603,GO:0051716,GO:0052637,GO:0055114,GO:0061630,GO:0061659,GO:0070534,GO:0070647,GO:0071704,GO:0072330,GO:0080132,GO:0080167,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901698,GO:1902494,GO:1990234 1.14.19.43 0.00000000000000000000001325 115.0
TH2_k127_3421980_15 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.000000000000000000003892 107.0
TH2_k127_3421980_16 Pfam:N_methyl_2 K02650 - - 0.00000000000000000001154 98.0
TH2_k127_3421980_18 Putative metal-binding motif - - - 0.000000000000000111 95.0
TH2_k127_3421980_19 amine dehydrogenase activity - - - 0.000000000000001967 90.0
TH2_k127_3421980_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.756e-205 654.0
TH2_k127_3421980_20 PFAM Extracellular ligand-binding receptor K07121 - - 0.00000000004597 76.0
TH2_k127_3421980_21 Heat shock 70 kDa protein K04043 - - 0.00000008892 64.0
TH2_k127_3421980_22 capsule polysaccharide biosynthetic process K16647 GO:0008150,GO:0040007 2.4.2.47 0.000001285 59.0
TH2_k127_3421980_3 Carbon starvation protein CstA K06200 - - 1.358e-199 643.0
TH2_k127_3421980_4 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 407.0
TH2_k127_3421980_5 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000008382 229.0
TH2_k127_3421980_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000001101 228.0
TH2_k127_3421980_7 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000106 175.0
TH2_k127_3421980_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000002356 141.0
TH2_k127_3421980_9 Sporulation related domain - - - 0.0000000000000000000000000000001212 135.0
TH2_k127_3422337_0 repeat protein - - - 1.253e-291 970.0
TH2_k127_3422337_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 2.301e-200 638.0
TH2_k127_3422337_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006599 469.0
TH2_k127_3422337_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 453.0
TH2_k127_3422337_4 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 386.0
TH2_k127_3422337_5 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000806 283.0
TH2_k127_3422337_6 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002496 253.0
TH2_k127_3422337_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001835 236.0
TH2_k127_3422337_8 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000000000000002852 178.0
TH2_k127_3422337_9 Transposase IS4 family protein - - - 0.0003133 43.0
TH2_k127_3423673_0 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 468.0
TH2_k127_3423673_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 431.0
TH2_k127_3423673_10 Belongs to the GbsR family - - - 0.00000000000000000000000000000000000001302 151.0
TH2_k127_3423673_2 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 326.0
TH2_k127_3423673_3 phospho-2-dehydro-3-deoxyheptonate aldolase K01626,K03856,K04516,K13853 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 325.0
TH2_k127_3423673_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 306.0
TH2_k127_3423673_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 293.0
TH2_k127_3423673_6 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001373 284.0
TH2_k127_3423673_7 chorismate binding enzyme K01851,K02361,K02552 - 5.4.4.2 0.000000000000000000000000000000000000000000000000000000000003617 234.0
TH2_k127_3423673_8 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000001115 168.0
TH2_k127_3423673_9 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.0000000000000000000000000000000000000000007047 166.0
TH2_k127_3460968_0 NADH:flavin oxidoreductase / NADH oxidase family K09461 - 1.14.13.40 4.955e-303 947.0
TH2_k127_3460968_1 heat shock protein binding - - - 1.883e-249 796.0
TH2_k127_3460968_10 Lysin motif - - - 0.00000000000000000000000000000005663 132.0
TH2_k127_3460968_11 Prokaryotic N-terminal methylation motif K02650 - - 0.00000000000000000000000000008223 133.0
TH2_k127_3460968_12 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000000000000000000009069 121.0
TH2_k127_3460968_13 sterol carrier protein - - - 0.00000000001634 76.0
TH2_k127_3460968_2 PFAM Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 551.0
TH2_k127_3460968_3 Zinc-binding dehydrogenase K14446 - 1.3.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 469.0
TH2_k127_3460968_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000527 254.0
TH2_k127_3460968_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.00000000000000000000000000000000000000000000000000000002519 202.0
TH2_k127_3460968_7 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.00000000000000000000000000000000000000003621 156.0
TH2_k127_3460968_9 MaoC like domain K14449,K18290 - 4.2.1.148,4.2.1.56 0.000000000000000000000000000000000002957 141.0
TH2_k127_3470837_0 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 533.0
TH2_k127_3470837_1 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002322 252.0
TH2_k127_3470837_10 PilZ domain - - - 0.0001644 53.0
TH2_k127_3470837_11 Tetratricopeptide repeat - - - 0.0005911 49.0
TH2_k127_3470837_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000005783 231.0
TH2_k127_3470837_3 FCD K05799 - - 0.0000000000000000000000000000000000000000000000000000000000003171 218.0
TH2_k127_3470837_4 Negative regulator of - - - 0.000000000000000000000000000000000000000000002912 183.0
TH2_k127_3470837_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000009933 151.0
TH2_k127_3470837_6 4Fe-4S dicluster domain K02573 - - 0.00000000000000000000000000000004209 133.0
TH2_k127_3470837_7 DnaJ molecular chaperone homology domain - - - 0.0000000000000001754 93.0
TH2_k127_3470837_8 Belongs to the MtfA family K09933 - - 0.00001029 56.0
TH2_k127_3470837_9 Protein of unknown function (DUF2505) - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.00006473 53.0
TH2_k127_347332_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 533.0
TH2_k127_347332_1 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 492.0
TH2_k127_347332_10 PFAM Aldo keto reductase family - - - 0.0000000000000000000000000000000000000000000000002618 188.0
TH2_k127_347332_11 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000001335 168.0
TH2_k127_347332_12 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000139 161.0
TH2_k127_347332_13 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000003028 143.0
TH2_k127_347332_14 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000157 117.0
TH2_k127_347332_15 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000004396 109.0
TH2_k127_347332_16 Permeases of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000005191 101.0
TH2_k127_347332_18 - - - - 0.00000000000009695 80.0
TH2_k127_347332_19 repeat protein - - - 0.000001142 61.0
TH2_k127_347332_2 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 363.0
TH2_k127_347332_3 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 378.0
TH2_k127_347332_4 COG1125 ABC-type proline glycine betaine transport systems ATPase components K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 301.0
TH2_k127_347332_5 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 288.0
TH2_k127_347332_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009406 289.0
TH2_k127_347332_7 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001096 281.0
TH2_k127_347332_8 Protein kinase domain K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001887 258.0
TH2_k127_347332_9 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002967 263.0
TH2_k127_3485386_0 - - - - 0.0006452 48.0
TH2_k127_3489403_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009373 401.0
TH2_k127_3489403_1 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 341.0
TH2_k127_3489403_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000006654 160.0
TH2_k127_3489403_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000001148 157.0
TH2_k127_3489403_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000002793 111.0
TH2_k127_3489403_5 acetyltransferase - - - 0.00000000000000003207 91.0
TH2_k127_3489403_6 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.00000000000007812 81.0
TH2_k127_3489403_7 cheY-homologous receiver domain K02490 - - 0.00000001588 63.0
TH2_k127_3491129_0 heat shock protein binding - - - 1.966e-227 731.0
TH2_k127_3491129_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 631.0
TH2_k127_3491129_12 Lamin Tail Domain - - - 0.000000000007884 68.0
TH2_k127_3491129_14 ) H( ) antiporter that extrudes sodium in exchange for external protons - - - 0.00006674 53.0
TH2_k127_3491129_2 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 463.0
TH2_k127_3491129_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 348.0
TH2_k127_3491129_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 301.0
TH2_k127_3491129_5 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 291.0
TH2_k127_3491129_6 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 289.0
TH2_k127_3491129_7 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005434 293.0
TH2_k127_3491129_8 heat shock protein binding - - - 0.0000000000000000000000000000000002706 152.0
TH2_k127_3491129_9 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000007315 148.0
TH2_k127_3493157_0 response regulator K07714 - - 1.519e-215 679.0
TH2_k127_3493157_1 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 490.0
TH2_k127_3493157_10 Transposase IS116 IS110 IS902 family protein K07486 - - 0.00007344 45.0
TH2_k127_3493157_2 Belongs to the ABC transporter superfamily K02031,K12371,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 396.0
TH2_k127_3493157_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 349.0
TH2_k127_3493157_4 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001447 268.0
TH2_k127_3493157_5 Protein of unknown function (DUF2723) - - - 0.00000000000000000000000000000000000000000000000000000009883 216.0
TH2_k127_3493157_6 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.00000000000000000000000000000000000000000000000009813 180.0
TH2_k127_3493157_7 - - - - 0.000000000000000000000000000000000000000002207 179.0
TH2_k127_3493157_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000033 127.0
TH2_k127_3493157_9 - - - - 0.000000008337 68.0
TH2_k127_3493674_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 510.0
TH2_k127_3493674_1 Retinal pigment epithelial membrane protein K11159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 486.0
TH2_k127_3493674_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 449.0
TH2_k127_3493674_3 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 392.0
TH2_k127_3493674_4 conserved protein (DUF2183) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 323.0
TH2_k127_3493674_5 thiolester hydrolase activity K00627,K06889 - 2.3.1.12 0.00000000000000000000000000000000000000000000001734 182.0
TH2_k127_3493674_6 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000001331 185.0
TH2_k127_3493674_7 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.00000003612 67.0
TH2_k127_3508700_0 Major facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 357.0
TH2_k127_3508700_1 Metal binding domain of Ada K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000004149 217.0
TH2_k127_3508700_2 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000001508 173.0
TH2_k127_3508700_3 radical SAM domain protein - - - 0.00000000000002302 76.0
TH2_k127_3509412_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 330.0
TH2_k127_3509412_1 transposase IS116 IS110 IS902 family K07486 - - 0.0000000000000000000000000000000000000000000000000000008832 201.0
TH2_k127_3509412_2 Fic/DOC family K07341 - - 0.00000000000000000000000000002005 119.0
TH2_k127_3509412_3 - K01865 - 5.4.4.1 0.00000000000000000001154 97.0
TH2_k127_3509412_4 PFAM Ribbon-helix-helix protein, copG family K21495 - - 0.0002962 43.0
TH2_k127_3509412_5 Fic/DOC family K07341 - - 0.0007204 44.0
TH2_k127_3516713_0 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000328 269.0
TH2_k127_3516713_1 CHAT domain - - - 0.0000000000000000000000000000000000003972 157.0
TH2_k127_3516713_2 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000001717 133.0
TH2_k127_3516713_3 histone H2A K63-linked ubiquitination - - - 0.000000000000000000006963 103.0
TH2_k127_3543317_0 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 406.0
TH2_k127_3543317_1 seryl-tRNA synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 370.0
TH2_k127_3543317_10 - - - - 0.00000000000000000000000000000112 136.0
TH2_k127_3543317_11 PFAM Glycoside hydrolase, family 2 K01192 - 3.2.1.25 0.000000000000000000000000000003843 129.0
TH2_k127_3543317_12 protein SCO1 SenC K07152 - - 0.00000000000000000000000000001239 132.0
TH2_k127_3543317_13 Alpha/beta hydrolase family - - - 0.00000000000000000000000000001397 133.0
TH2_k127_3543317_14 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000521 104.0
TH2_k127_3543317_15 Phosphopantetheine attachment site - - - 0.000000000000000000003545 98.0
TH2_k127_3543317_16 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000001498 104.0
TH2_k127_3543317_17 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000001693 70.0
TH2_k127_3543317_18 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000002167 59.0
TH2_k127_3543317_2 - K14949 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 326.0
TH2_k127_3543317_3 Domain of unknown function (DUF1839) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 305.0
TH2_k127_3543317_4 Lipopolysaccharide kinase (Kdo/WaaP) family K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 306.0
TH2_k127_3543317_5 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000004124 260.0
TH2_k127_3543317_6 Belongs to the peptidase S1B family K01183,K03791 - 3.2.1.14 0.0000000000000000000000000000000000000000000000000000001577 214.0
TH2_k127_3543317_7 FHA domain - - - 0.000000000000000000000000000000000000000000000000000006268 206.0
TH2_k127_3543317_8 Phosphate acyltransferases K13507 - 2.3.1.15,2.3.1.42 0.00000000000000000000000000000000000000000000001003 189.0
TH2_k127_3573257_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1168.0
TH2_k127_3573257_1 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001374 285.0
TH2_k127_3573257_10 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000001014 61.0
TH2_k127_3573257_11 START domain - - - 0.0000004444 61.0
TH2_k127_3573257_12 Uncharacterised nucleotidyltransferase - - - 0.000009668 57.0
TH2_k127_3573257_2 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002373 272.0
TH2_k127_3573257_3 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001481 273.0
TH2_k127_3573257_4 Radical SAM domain protein K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000011 256.0
TH2_k127_3573257_5 - - - - 0.00000000000000000000000000000000000000000000000000001001 214.0
TH2_k127_3573257_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000001136 197.0
TH2_k127_3573257_7 response regulator K02282,K02482 - 2.7.13.3 0.00000000000000000000000000000000000003035 156.0
TH2_k127_3573257_8 phosphatidylcholine synthase activity K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.00000000000000000000000000000005514 135.0
TH2_k127_3573257_9 - - - - 0.000000000000000000000000009075 127.0
TH2_k127_3612817_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 9.01e-278 868.0
TH2_k127_3612817_1 - - - - 0.000001181 53.0
TH2_k127_3636398_0 DNA polymerase A domain K02335 - 2.7.7.7 1.205e-208 686.0
TH2_k127_3636398_1 oxidoreductase activity - - - 0.00000000001183 70.0
TH2_k127_3673323_0 Large family of predicted nucleotide-binding domains K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002398 257.0
TH2_k127_3673323_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000006346 256.0
TH2_k127_3673323_2 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000007786 136.0
TH2_k127_3673626_0 ABC transporter, ATP-binding protein - - - 9.143e-214 677.0
TH2_k127_3673626_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.55e-204 654.0
TH2_k127_3673626_10 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000005719 235.0
TH2_k127_3673626_11 Trypsin-like serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000002166 239.0
TH2_k127_3673626_12 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000006684 190.0
TH2_k127_3673626_13 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000001621 193.0
TH2_k127_3673626_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000005663 174.0
TH2_k127_3673626_15 Helix-turn-helix domain - - - 0.00000000000000000000000000000000006385 155.0
TH2_k127_3673626_16 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000106 138.0
TH2_k127_3673626_17 - - - - 0.00000000000001823 85.0
TH2_k127_3673626_18 TonB dependent receptor - - - 0.00004021 56.0
TH2_k127_3673626_19 ATPase involved in DNA repair - - - 0.0001658 50.0
TH2_k127_3673626_2 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 517.0
TH2_k127_3673626_20 Zinc dependent phospholipase C - - - 0.0002257 53.0
TH2_k127_3673626_3 response regulator K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 488.0
TH2_k127_3673626_4 Dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 442.0
TH2_k127_3673626_5 Splits dipeptides with a prolyl residue in the C- terminal position K01271 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 391.0
TH2_k127_3673626_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 334.0
TH2_k127_3673626_7 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 325.0
TH2_k127_3673626_8 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 300.0
TH2_k127_3673626_9 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000001358 241.0
TH2_k127_3687590_0 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000009038 235.0
TH2_k127_3687590_1 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000001498 229.0
TH2_k127_3687590_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000003423 209.0
TH2_k127_3687590_3 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000004246 180.0
TH2_k127_3693582_0 Amino acid permease - - - 3.062e-226 719.0
TH2_k127_3693582_1 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 453.0
TH2_k127_3693582_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000001632 83.0
TH2_k127_3704072_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 593.0
TH2_k127_3704072_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 388.0
TH2_k127_3704072_10 serine threonine protein kinase - - - 0.00000000000000000000000003798 123.0
TH2_k127_3704072_11 Histidine kinase K01768,K03406,K11617 - 2.7.13.3,4.6.1.1 0.000000000000000000000005704 109.0
TH2_k127_3704072_12 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000007839 65.0
TH2_k127_3704072_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 374.0
TH2_k127_3704072_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002807 265.0
TH2_k127_3704072_4 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000004714 196.0
TH2_k127_3704072_5 pfkB family carbohydrate kinase K00847,K03338 - 2.7.1.4,2.7.1.92 0.0000000000000000000000000000000000000000000000003877 192.0
TH2_k127_3704072_6 NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000189 180.0
TH2_k127_3704072_7 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000007739 177.0
TH2_k127_3704072_8 Protein of unknown function (DUF1698) - - - 0.00000000000000000000000000000000000001158 165.0
TH2_k127_3704072_9 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000001119 143.0
TH2_k127_3745585_0 GTP-binding protein K06207 - - 3.934e-270 843.0
TH2_k127_3745585_1 Glucose / Sorbosone dehydrogenase - - - 3.419e-209 672.0
TH2_k127_3745585_10 domain, Protein - - - 0.00000000000000006617 94.0
TH2_k127_3745585_11 High confidence in function and specificity - - - 0.00000004857 57.0
TH2_k127_3745585_12 High confidence in function and specificity - - - 0.000001342 55.0
TH2_k127_3745585_13 High confidence in function and specificity - - - 0.000004204 52.0
TH2_k127_3745585_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 445.0
TH2_k127_3745585_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 357.0
TH2_k127_3745585_4 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000001447 242.0
TH2_k127_3745585_5 COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain) - - - 0.0000000000000000000000000000000000000000000000000000000000004951 216.0
TH2_k127_3745585_6 L-Ala-D L-amino acid - - - 0.0000000000000000000000000000000000000000000002054 189.0
TH2_k127_3745585_7 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000002879 154.0
TH2_k127_3745585_8 belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000005986 136.0
TH2_k127_3745585_9 phosphorelay signal transduction system - - - 0.000000000000000000000000002615 119.0
TH2_k127_376179_0 Protein kinase; unclassified specificity. K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 590.0
TH2_k127_376179_1 Psort location Cytoplasmic, score 9.97 K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 491.0
TH2_k127_376179_10 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004142 269.0
TH2_k127_376179_11 PFAM Glycosyl transferase, group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000005971 262.0
TH2_k127_376179_12 Two component signalling adaptor domain K02487,K06596 - - 0.000000000000000000000000000000000000000000000000000000000000000884 246.0
TH2_k127_376179_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000006925 203.0
TH2_k127_376179_14 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000494 203.0
TH2_k127_376179_15 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000001485 216.0
TH2_k127_376179_16 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000006025 194.0
TH2_k127_376179_17 GtrA-like protein K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000374 199.0
TH2_k127_376179_18 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000005833 190.0
TH2_k127_376179_19 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000004794 187.0
TH2_k127_376179_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 445.0
TH2_k127_376179_20 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000004625 165.0
TH2_k127_376179_21 Zinc-dependent metalloprotease - - - 0.0000000000000000000000000000000001434 151.0
TH2_k127_376179_22 PFAM Formylglycine-generating sulfatase enzyme K12132 - 2.7.11.1 0.000000000000000000000000000004236 136.0
TH2_k127_376179_23 Thioesterase-like superfamily K01075 - 3.1.2.23 0.00000000000000000000000000001112 122.0
TH2_k127_376179_24 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.00000000000000000000000000001854 133.0
TH2_k127_376179_25 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000001056 119.0
TH2_k127_376179_26 NUDIX domain - - - 0.0000000000000000000000000002659 126.0
TH2_k127_376179_27 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000004643 99.0
TH2_k127_376179_28 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000292 94.0
TH2_k127_376179_29 Acetyltransferase (GNAT) domain - - - 0.000000000001191 76.0
TH2_k127_376179_3 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 404.0
TH2_k127_376179_30 Cysteine-rich CPXCG - - - 0.0000000006246 64.0
TH2_k127_376179_31 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000001554 66.0
TH2_k127_376179_33 TPR repeat - - - 0.00000131 59.0
TH2_k127_376179_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 390.0
TH2_k127_376179_5 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 374.0
TH2_k127_376179_6 Mediates influx of magnesium ions K03284,K16074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001409 288.0
TH2_k127_376179_7 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003001 272.0
TH2_k127_376179_8 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000004754 263.0
TH2_k127_376179_9 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000009653 250.0
TH2_k127_3828789_0 endonuclease exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000004713 179.0
TH2_k127_3828789_1 Phytanoyl-CoA dioxygenase (PhyH) K21195 - 1.14.11.46 0.0000000000000000000000000000000000001048 144.0
TH2_k127_3828789_2 Stealth protein CR2, conserved region 2 - - - 0.0000000000000000000000000000000000007558 152.0
TH2_k127_3852124_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.71e-267 840.0
TH2_k127_3852124_1 DNA helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 592.0
TH2_k127_3852124_10 Calcium ion binding - GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.000000000000000000263 103.0
TH2_k127_3852124_12 dienelactone hydrolase - - - 0.000000000001379 79.0
TH2_k127_3852124_13 PEGA domain - - - 0.00000000004626 76.0
TH2_k127_3852124_14 - - - - 0.0001155 49.0
TH2_k127_3852124_2 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 501.0
TH2_k127_3852124_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 462.0
TH2_k127_3852124_4 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 347.0
TH2_k127_3852124_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 319.0
TH2_k127_3852124_6 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001617 302.0
TH2_k127_3852124_8 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004623 268.0
TH2_k127_3852124_9 Smr domain - - - 0.00000000000000000000000000000000000000000000000354 181.0
TH2_k127_3857601_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 5.981e-225 715.0
TH2_k127_3857601_1 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 400.0
TH2_k127_3857601_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 406.0
TH2_k127_3857601_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000007823 163.0
TH2_k127_3926341_0 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 507.0
TH2_k127_3926341_1 Stage II sporulation protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 431.0
TH2_k127_3926341_2 virulence factor MVIN family protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 379.0
TH2_k127_3926341_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000901 260.0
TH2_k127_3926341_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000498 237.0
TH2_k127_3926341_5 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000008496 218.0
TH2_k127_3926341_6 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000001113 160.0
TH2_k127_3975180_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1373.0
TH2_k127_3975180_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 7.112e-292 902.0
TH2_k127_3975180_10 PFAM Serine threonine protein kinase-related K12132 - 2.7.11.1 0.0000000000000000000000000000009768 133.0
TH2_k127_3975180_11 NUDIX domain - - - 0.000000000000000000000000001443 129.0
TH2_k127_3975180_12 Transposase Tn5 dimerisation domain - - - 0.00000000000000000000001393 116.0
TH2_k127_3975180_13 - - - - 0.000000000003781 76.0
TH2_k127_3975180_14 peptidase - - - 0.00000296 56.0
TH2_k127_3975180_2 Aldehyde dehydrogenase family K02618,K15514 - 1.2.1.77,1.2.1.91,3.3.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 576.0
TH2_k127_3975180_3 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 475.0
TH2_k127_3975180_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 415.0
TH2_k127_3975180_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003971 292.0
TH2_k127_3975180_6 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000007346 255.0
TH2_k127_3975180_7 response regulator K14979 - - 0.0000000000000000000000000000000000000001256 158.0
TH2_k127_3975180_8 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000001745 139.0
TH2_k127_3975180_9 Histidine kinase - - - 0.0000000000000000000000000000000444 135.0
TH2_k127_403513_1 fumarate reductase K00239 - 1.3.5.1,1.3.5.4 0.0000000000218 76.0
TH2_k127_4043066_0 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 608.0
TH2_k127_4043066_1 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 499.0
TH2_k127_4043066_2 Multicopper K04753 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 435.0
TH2_k127_4043066_3 Peptidase C26 K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000001526 191.0
TH2_k127_4043066_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000006493 123.0
TH2_k127_4043066_5 Belongs to the ompA family K20276 - - 0.00000000000006425 81.0
TH2_k127_4043066_6 COG0517 FOG CBS domain - - - 0.0000000000004767 79.0
TH2_k127_4086469_0 ACT domain K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 497.0
TH2_k127_4086469_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000001034 205.0
TH2_k127_4086469_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000001138 164.0
TH2_k127_4086469_5 Transposase IS4 family protein - - - 0.000000000005528 68.0
TH2_k127_4172147_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 346.0
TH2_k127_4172147_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 347.0
TH2_k127_4172147_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000001352 103.0
TH2_k127_4193977_0 Translation, ribosomal structure and biogenesis K08301 - - 1.026e-232 728.0
TH2_k127_4193977_1 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 328.0
TH2_k127_4193977_2 Maf-like protein K06287 - - 0.000000000000000000000001883 104.0
TH2_k127_4231215_0 MaoC like domain K14449,K18290 - 4.2.1.148,4.2.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 389.0
TH2_k127_4231215_1 Acyl-CoA dehydrogenase, middle domain K14448 - 1.3.8.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 381.0
TH2_k127_4231215_2 FIST N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000631 304.0
TH2_k127_4231215_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000002073 226.0
TH2_k127_4231215_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000002895 215.0
TH2_k127_4231215_5 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000003669 217.0
TH2_k127_4293022_0 PFAM Carbamoyltransferase K00612 - - 6.965e-197 632.0
TH2_k127_4293022_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009333 454.0
TH2_k127_4293022_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 299.0
TH2_k127_4293022_3 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000007828 218.0
TH2_k127_4293022_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000005956 192.0
TH2_k127_4293022_5 transferase activity, transferring acyl groups other than amino-acyl groups K08301 - - 0.00000000000000000009825 98.0
TH2_k127_4293022_6 OmpA family K03286 - - 0.0000000000000000106 90.0
TH2_k127_4293022_8 FG-GAP repeat - - - 0.000003445 59.0
TH2_k127_4300378_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 523.0
TH2_k127_4300378_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 433.0
TH2_k127_4300378_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 413.0
TH2_k127_4300378_3 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000002917 198.0
TH2_k127_4300378_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000005107 180.0
TH2_k127_4331714_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 572.0
TH2_k127_4331714_1 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 393.0
TH2_k127_4331714_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 357.0
TH2_k127_4331714_3 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 323.0
TH2_k127_4331714_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 317.0
TH2_k127_4331714_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000001881 62.0
TH2_k127_433229_0 Pfam Major Facilitator Superfamily - - - 3.123e-198 630.0
TH2_k127_433229_1 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 444.0
TH2_k127_433229_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 331.0
TH2_k127_433229_3 PFAM Rhodanese domain protein K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000152 268.0
TH2_k127_433229_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000002075 215.0
TH2_k127_433229_5 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000004287 158.0
TH2_k127_433229_6 hemerythrin HHE cation binding domain - - - 0.00000000000000002467 84.0
TH2_k127_433229_7 - - - - 0.0000000000004863 74.0
TH2_k127_4333830_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000002865 238.0
TH2_k127_4333830_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000005423 201.0
TH2_k127_4333830_2 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000006358 164.0
TH2_k127_4333830_3 Glutamine amidotransferases class-II - - - 0.000000000000000000000000000000000000001955 158.0
TH2_k127_4333830_4 Helix-turn-helix domain K15539 - - 0.0000000005498 63.0
TH2_k127_4333830_5 Type IV pilus biogenesis K02656 - - 0.0000002669 61.0
TH2_k127_433935_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 300.0
TH2_k127_433935_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000471 239.0
TH2_k127_433935_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001699 237.0
TH2_k127_433935_3 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000009735 186.0
TH2_k127_433935_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000374 128.0
TH2_k127_433935_5 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000009738 132.0
TH2_k127_433935_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000003196 119.0
TH2_k127_4339643_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 8.96e-265 844.0
TH2_k127_4339643_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 535.0
TH2_k127_4339643_10 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000004226 192.0
TH2_k127_4339643_11 B domain of TMEM189, localisation domain K20656 - - 0.000000000000000000000000000000000000000000000005112 180.0
TH2_k127_4339643_12 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000003735 100.0
TH2_k127_4339643_13 PFAM membrane protein of K08972 - - 0.000000000000002679 81.0
TH2_k127_4339643_14 Endonuclease Exonuclease Phosphatase - - - 0.00000001196 67.0
TH2_k127_4339643_2 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 478.0
TH2_k127_4339643_3 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 470.0
TH2_k127_4339643_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 449.0
TH2_k127_4339643_5 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 372.0
TH2_k127_4339643_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 308.0
TH2_k127_4339643_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 321.0
TH2_k127_4339643_8 deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000008953 246.0
TH2_k127_4339643_9 Polysaccharide biosynthesis protein K01784,K02473 - 5.1.3.2,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000008991 235.0
TH2_k127_4377365_0 4Fe-4S dicluster domain - - - 1.334e-217 698.0
TH2_k127_4377365_1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 411.0
TH2_k127_4377365_10 Trm112p-like protein K09791 - - 0.00003292 49.0
TH2_k127_4377365_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000002546 225.0
TH2_k127_4377365_3 Phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000001265 223.0
TH2_k127_4377365_4 COG1233 Phytoene dehydrogenase and related - - - 0.000000000000000000000000000000000000000000000000000007911 208.0
TH2_k127_4377365_5 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000002757 215.0
TH2_k127_4377365_6 response regulator K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000006386 166.0
TH2_k127_4377365_7 Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000002475 138.0
TH2_k127_4377365_8 PilZ domain - - - 0.000000000001337 74.0
TH2_k127_4377365_9 Transcriptional regulator, CarD family K07736 - - 0.00002419 46.0
TH2_k127_447381_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 424.0
TH2_k127_4515867_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 1.813e-272 849.0
TH2_k127_4515867_1 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 522.0
TH2_k127_4515867_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00001364 59.0
TH2_k127_4515867_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 503.0
TH2_k127_4515867_3 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 473.0
TH2_k127_4515867_4 TIGRFAM argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 379.0
TH2_k127_4515867_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000001652 257.0
TH2_k127_4515867_6 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006694 259.0
TH2_k127_4515867_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000004738 248.0
TH2_k127_4515867_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000001129 154.0
TH2_k127_4515867_9 PFAM methyltransferase - - - 0.00000000004825 72.0
TH2_k127_4530754_0 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001298 252.0
TH2_k127_4530754_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000002344 143.0
TH2_k127_4530754_2 sporulation resulting in formation of a cellular spore K06381 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000002688 145.0
TH2_k127_4550317_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.884e-284 893.0
TH2_k127_4550317_1 S1, RNA binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 347.0
TH2_k127_4550317_2 Phospholipase - - - 0.0000000000000000000000000000000000000000000000913 188.0
TH2_k127_4550317_3 DNA/RNA non-specific endonuclease K01173 - - 0.000000000000000000000000000000000000003071 164.0
TH2_k127_4550317_5 serine-type endopeptidase activity - - - 0.00000001554 66.0
TH2_k127_4555665_0 3D domain - - - 0.000000000000000000000000000000000000000000000000000000000000001238 233.0
TH2_k127_4555665_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000002315 210.0
TH2_k127_4555665_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000003608 61.0
TH2_k127_4561052_0 helicase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001708 243.0
TH2_k127_4561052_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000001247 83.0
TH2_k127_4561052_2 Psort location Cytoplasmic, score - - - 0.0000000000004358 72.0
TH2_k127_4561052_4 - - - - 0.00004849 48.0
TH2_k127_4606026_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 522.0
TH2_k127_4606026_1 transcription factor binding K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 377.0
TH2_k127_4606026_2 COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000419 278.0
TH2_k127_4606026_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000001304 195.0
TH2_k127_4606026_4 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000001644 154.0
TH2_k127_4606026_5 Nudix hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000002339 141.0
TH2_k127_4606026_6 histone H2A K63-linked ubiquitination K01768,K03529 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 4.6.1.1 0.0000000000000000000000002989 109.0
TH2_k127_4606026_7 Serine Threonine protein kinase K08884 - 2.7.11.1 0.000001029 52.0
TH2_k127_4616195_0 AMP-binding enzyme K01897 - 6.2.1.3 7.039e-220 697.0
TH2_k127_4616195_1 PFAM Copper amine oxidase, N2 domain K00276 - 1.4.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 558.0
TH2_k127_4616195_10 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000002554 119.0
TH2_k127_4616195_11 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000001412 61.0
TH2_k127_4616195_12 Domain of unknown function K20276 - - 0.0001565 55.0
TH2_k127_4616195_13 Protein of unknown function, DUF255 - - - 0.0004837 51.0
TH2_k127_4616195_2 Site-specific recombinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 428.0
TH2_k127_4616195_3 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 328.0
TH2_k127_4616195_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 316.0
TH2_k127_4616195_5 phosphoprotein phosphatase activity K07313 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000001373 235.0
TH2_k127_4616195_6 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000002117 220.0
TH2_k127_4616195_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000005681 203.0
TH2_k127_4616195_8 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000006598 164.0
TH2_k127_4616195_9 - - - - 0.0000000000000000000000000000000000544 146.0
TH2_k127_468310_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 600.0
TH2_k127_468310_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 575.0
TH2_k127_468310_10 Transglycosylase associated protein - - - 0.0000663 50.0
TH2_k127_468310_11 Peptidase s1 and s6 chymotrypsin hap K08372 - - 0.0001367 53.0
TH2_k127_468310_2 Flavin-binding monooxygenase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 539.0
TH2_k127_468310_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 324.0
TH2_k127_468310_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004885 286.0
TH2_k127_468310_5 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000001746 207.0
TH2_k127_468310_6 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000001918 202.0
TH2_k127_468310_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000002851 189.0
TH2_k127_468310_8 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000001896 100.0
TH2_k127_4700753_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 522.0
TH2_k127_4700753_1 Short chain fatty K02106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 400.0
TH2_k127_4700753_10 Type IV minor pilin ComP, DNA uptake sequence receptor K02650 - - 0.00000000704 64.0
TH2_k127_4700753_2 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001085 269.0
TH2_k127_4700753_4 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000002177 159.0
TH2_k127_4700753_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001158 157.0
TH2_k127_4700753_6 Prokaryotic N-terminal methylation motif K02650 - - 0.00000000000000000000000000003938 124.0
TH2_k127_4700753_7 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000000000000000000002834 122.0
TH2_k127_4700753_8 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000001216 114.0
TH2_k127_4700753_9 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000008632 103.0
TH2_k127_4700780_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000002829 275.0
TH2_k127_4700780_1 PFAM Type IV pilus assembly PilZ - - - 0.0000000000006657 78.0
TH2_k127_476864_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 3.736e-216 687.0
TH2_k127_476864_1 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 493.0
TH2_k127_476864_2 General secretion pathway protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 411.0
TH2_k127_476864_3 general secretion pathway protein G K02456 - - 0.0005343 46.0
TH2_k127_4773696_0 Sarcosine oxidase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 463.0
TH2_k127_4773696_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 327.0
TH2_k127_4773696_2 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000003207 104.0
TH2_k127_4773696_3 Belongs to the GcvT family K00302,K10815 - 1.4.99.5,1.5.3.1 0.0000000000000008517 81.0
TH2_k127_4773696_4 Belongs to the UPF0235 family K09131 - - 0.000000000002391 71.0
TH2_k127_4773696_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000657 64.0
TH2_k127_4797549_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 602.0
TH2_k127_4797549_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 522.0
TH2_k127_4797549_10 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 331.0
TH2_k127_4797549_11 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 301.0
TH2_k127_4797549_12 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 321.0
TH2_k127_4797549_13 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006712 291.0
TH2_k127_4797549_14 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001041 262.0
TH2_k127_4797549_15 Catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000000000001667 201.0
TH2_k127_4797549_16 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000009698 197.0
TH2_k127_4797549_17 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000006945 198.0
TH2_k127_4797549_18 Chemotaxis protein CheY K03413 - - 0.000000000000000000000000000000000000000000000001683 176.0
TH2_k127_4797549_19 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000000000000003249 179.0
TH2_k127_4797549_2 Belongs to the aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 512.0
TH2_k127_4797549_20 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000001762 191.0
TH2_k127_4797549_21 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000546 150.0
TH2_k127_4797549_22 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000005284 149.0
TH2_k127_4797549_23 - - - - 0.0000000000000000000000000000000008947 140.0
TH2_k127_4797549_24 Chemotaxis protein CheY K03413 - - 0.00000000000000000000000000000007888 128.0
TH2_k127_4797549_25 zinc-ribbon domain - - - 0.000000000000000000000000000006507 128.0
TH2_k127_4797549_26 Cytosol aminopeptidase family, N-terminal domain - - - 0.0000000000000000000000000001405 126.0
TH2_k127_4797549_27 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000001829 123.0
TH2_k127_4797549_28 protein involved in tolerance to divalent cations K03926 - - 0.0000000000000000000000000002249 131.0
TH2_k127_4797549_29 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000002261 125.0
TH2_k127_4797549_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 410.0
TH2_k127_4797549_30 PFAM CheW domain protein K03408 - - 0.0000000000000000000258 98.0
TH2_k127_4797549_31 HEAT repeat - - - 0.0000000000000000002839 103.0
TH2_k127_4797549_32 HB1, ASXL, restriction endonuclease HTH domain - - - 0.0000000000000000005854 102.0
TH2_k127_4797549_33 deoxyhypusine monooxygenase activity - - - 0.00000000000000005194 92.0
TH2_k127_4797549_34 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000004324 88.0
TH2_k127_4797549_35 Glycosyl transferase family 41 - - - 0.0000000004707 72.0
TH2_k127_4797549_36 Helix-hairpin-helix motif K02237 - - 0.000002841 56.0
TH2_k127_4797549_4 protein catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 382.0
TH2_k127_4797549_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 391.0
TH2_k127_4797549_6 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 355.0
TH2_k127_4797549_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 343.0
TH2_k127_4797549_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 325.0
TH2_k127_4797549_9 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 324.0
TH2_k127_4820005_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 9.789e-223 698.0
TH2_k127_4820005_1 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00146,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 615.0
TH2_k127_4820005_10 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000324 143.0
TH2_k127_4820005_11 Pfam Hemerythrin HHE - - - 0.0000004926 57.0
TH2_k127_4820005_13 cellulose binding - - - 0.0001283 55.0
TH2_k127_4820005_2 Cysteine synthase K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 563.0
TH2_k127_4820005_3 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 499.0
TH2_k127_4820005_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 466.0
TH2_k127_4820005_5 Phage shock protein A, PspA K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001911 287.0
TH2_k127_4820005_6 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000246 271.0
TH2_k127_4820005_7 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000002413 247.0
TH2_k127_4820005_8 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000003653 212.0
TH2_k127_4820005_9 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000006193 203.0
TH2_k127_4827571_0 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 503.0
TH2_k127_4827571_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 411.0
TH2_k127_4827571_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008577 252.0
TH2_k127_4827571_3 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000001207 218.0
TH2_k127_4827571_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000009042 190.0
TH2_k127_4827571_5 PFAM acyltransferase 3 - - - 0.00000000000000000000000000000000000000000000001332 176.0
TH2_k127_4827571_6 alpha beta - - - 0.0000000000000000000000000000000000663 147.0
TH2_k127_4831256_0 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 455.0
TH2_k127_4831256_1 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000006959 238.0
TH2_k127_4831256_2 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000002344 172.0
TH2_k127_4847677_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.936e-255 801.0
TH2_k127_4847677_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 576.0
TH2_k127_4847677_10 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075 - 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000000000166 165.0
TH2_k127_4847677_11 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000006229 114.0
TH2_k127_4847677_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000004092 80.0
TH2_k127_4847677_13 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000008959 76.0
TH2_k127_4847677_14 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000001633 70.0
TH2_k127_4847677_15 Stigma-specific protein, Stig1 - - - 0.0000001216 63.0
TH2_k127_4847677_2 Uncharacterized protein conserved in bacteria (DUF2130) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 427.0
TH2_k127_4847677_3 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 411.0
TH2_k127_4847677_4 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 325.0
TH2_k127_4847677_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 321.0
TH2_k127_4847677_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000006779 272.0
TH2_k127_4847677_7 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000001311 244.0
TH2_k127_4847677_8 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000511 238.0
TH2_k127_4847677_9 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.0000000000000000000000000000000000000000004191 170.0
TH2_k127_4865958_0 lipid kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003002 262.0
TH2_k127_4865958_1 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000008178 200.0
TH2_k127_4865958_2 oxidoreductase activity K07114 - - 0.00000000000004814 84.0
TH2_k127_4888235_0 COG0058 Glucan phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 330.0
TH2_k127_4888235_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000006377 181.0
TH2_k127_4888235_2 Alpha amylase, catalytic domain K00701 - 2.4.1.19 0.00000000000000000000000000000000001172 141.0
TH2_k127_4889627_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1971.0
TH2_k127_4889627_1 COG0515 Serine threonine protein kinase - - - 1.407e-253 821.0
TH2_k127_4889627_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 2.071e-206 652.0
TH2_k127_4889627_3 Rieske (2fe-2S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 389.0
TH2_k127_4889627_4 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 307.0
TH2_k127_4889627_5 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000003001 174.0
TH2_k127_4889627_6 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000001772 119.0
TH2_k127_4889627_7 Sulphur transport K07112 - - 0.00000000000000000000000004342 115.0
TH2_k127_4889627_8 Sulphur transport K07112 - - 0.00000000000000000000005286 111.0
TH2_k127_4889627_9 Domain of unknown function (DUF309) K09763 - - 0.000000000002743 72.0
TH2_k127_4893688_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1211.0
TH2_k127_4893688_1 Heat shock 70 kDa protein K04043 - - 3.814e-292 908.0
TH2_k127_4893688_10 MerR HTH family regulatory protein - - - 0.000000000000000000000000000000000000000000000000001968 189.0
TH2_k127_4893688_11 PilZ domain - - - 0.000000000000000000000000000000001209 147.0
TH2_k127_4893688_2 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 394.0
TH2_k127_4893688_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 332.0
TH2_k127_4893688_4 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 315.0
TH2_k127_4893688_5 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001707 287.0
TH2_k127_4893688_6 Imelysin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002375 276.0
TH2_k127_4893688_7 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000000000000003627 248.0
TH2_k127_4893688_8 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000008543 241.0
TH2_k127_4893688_9 Penicillin-insensitive murein endopeptidase K07261 - - 0.000000000000000000000000000000000000000000000000000000000004564 218.0
TH2_k127_4905245_0 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 449.0
TH2_k127_4905245_1 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006067 286.0
TH2_k127_4905245_2 Phosphohistidine phosphatase, SixA K08296 - - 0.000000000002821 73.0
TH2_k127_4919275_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 417.0
TH2_k127_4928530_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 488.0
TH2_k127_4928530_1 signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 485.0
TH2_k127_4928530_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 454.0
TH2_k127_4928530_3 sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 444.0
TH2_k127_4928530_4 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 375.0
TH2_k127_4928530_5 Protein kinase; unclassified specificity. K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 377.0
TH2_k127_4928530_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000007058 262.0
TH2_k127_4928530_7 phosphorelay sensor kinase activity K03885,K05962,K07675,K10716,K13598,K15011,K21696 - 1.6.99.3,2.7.13.1,2.7.13.3 0.0000000002234 70.0
TH2_k127_4929888_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 537.0
TH2_k127_4929888_1 Metal-dependent phosphohydrolase, HD region - - - 0.00000000000000000000000000000000000000000000001198 185.0
TH2_k127_4929888_2 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000001056 186.0
TH2_k127_4929888_3 Glutathione peroxidase - - - 0.00000000000000000002444 102.0
TH2_k127_4929888_4 domain, Protein - - - 0.0000000000003653 74.0
TH2_k127_4929888_5 Protein of unknown function, DUF547 - - - 0.0000000000004745 80.0
TH2_k127_4929888_6 Belongs to the AB hydrolase superfamily. MetX family K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000912 58.0
TH2_k127_4933916_0 Capsule synthesis protein K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 352.0
TH2_k127_4933916_1 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000006785 244.0
TH2_k127_4933916_2 Dienelactone hydrolase family K07100 - - 0.0000000000000000000000000000000000000000000000000000000000001126 225.0
TH2_k127_4933916_3 PKD domain - - - 0.000000000000000000000000000000000000000000000000000000000002442 225.0
TH2_k127_4972414_0 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 542.0
TH2_k127_4972414_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 490.0
TH2_k127_4972414_10 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.00000000009301 63.0
TH2_k127_4972414_2 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009832 254.0
TH2_k127_4972414_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000002701 248.0
TH2_k127_4972414_4 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000005368 206.0
TH2_k127_4972414_5 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000001807 213.0
TH2_k127_4972414_6 AMP binding - GO:0008150,GO:0040007 - 0.00000000000000000000000006097 121.0
TH2_k127_4972414_7 Universal stress protein - - - 0.0000000000000000000000009875 111.0
TH2_k127_4972414_8 - - - - 0.000000000000000000000001285 111.0
TH2_k127_4972414_9 - - - - 0.000000000000000000000002699 115.0
TH2_k127_498478_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 3.772e-308 962.0
TH2_k127_498478_1 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000002656 179.0
TH2_k127_498478_2 PFAM CHAD domain containing protein - - - 0.000000000000003757 85.0
TH2_k127_498478_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000003364 77.0
TH2_k127_4995446_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 473.0
TH2_k127_4995446_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 316.0
TH2_k127_4995446_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000007582 238.0
TH2_k127_4995446_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0007219 50.0
TH2_k127_4999600_0 Rod shape-determining protein K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 561.0
TH2_k127_4999600_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 523.0
TH2_k127_4999600_2 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 336.0
TH2_k127_4999600_3 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 310.0
TH2_k127_4999600_4 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000004375 238.0
TH2_k127_4999600_5 PFAM Phage-related baseplate assembly protein - - - 0.000000000000000000000000782 117.0
TH2_k127_4999600_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000001187 118.0
TH2_k127_4999600_7 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000009568 91.0
TH2_k127_4999600_8 PAAR motif - - - 0.00000000000001949 78.0
TH2_k127_5003831_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1056.0
TH2_k127_5003831_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.516e-269 852.0
TH2_k127_5003831_2 domain protein K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 478.0
TH2_k127_5003831_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.0000000000000000000000000000000000000000000000000000000000005286 222.0
TH2_k127_5003831_5 - - - - 0.00000000000004258 81.0
TH2_k127_5003831_6 ThiS family K03636 - - 0.000000005215 66.0
TH2_k127_5003831_7 serine threonine protein kinase K12132 - 2.7.11.1 0.00000361 53.0
TH2_k127_5042749_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1181.0
TH2_k127_5042749_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 609.0
TH2_k127_5042749_2 transferase activity, transferring hexosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 410.0
TH2_k127_5042749_3 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 378.0
TH2_k127_5042749_4 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000151 149.0
TH2_k127_5042749_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03972 - - 0.00000000000005642 75.0
TH2_k127_5066234_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 4.667e-310 974.0
TH2_k127_5066234_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.214e-255 798.0
TH2_k127_5066234_2 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 606.0
TH2_k127_5066234_3 imidazolonepropionase K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 344.0
TH2_k127_5066234_4 tRNA synthetases class II (D, K and N) K09759 - 6.1.1.23 0.00000000000000000000000000000000000001034 145.0
TH2_k127_5066234_5 Tetratricopeptide repeat - - - 0.000000000000000003937 100.0
TH2_k127_5082495_0 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000442 250.0
TH2_k127_5082495_1 Tetratricopeptide repeat - - - 0.00000000000000000000000005898 119.0
TH2_k127_5082495_2 Tetratricopeptide repeat - - - 0.00000000000004356 85.0
TH2_k127_5091486_0 Male sterility protein K01897 - 6.2.1.3 0.0 1461.0
TH2_k127_5091486_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1309.0
TH2_k127_5091486_10 Putative metal-binding motif - - - 0.00000000000000000000000000000000004961 147.0
TH2_k127_5091486_11 COG3806 Anti-sigma factor K07167 - - 0.00004835 51.0
TH2_k127_5091486_12 WD40 repeats - - - 0.0009658 51.0
TH2_k127_5091486_2 Domain of unknown function (DUF2088) - - - 2.184e-291 900.0
TH2_k127_5091486_3 Carboxyl transferase domain - - - 6.63e-226 716.0
TH2_k127_5091486_4 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004041 283.0
TH2_k127_5091486_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006487 273.0
TH2_k127_5091486_6 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000000000000000000000000000000001075 213.0
TH2_k127_5091486_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000003597 196.0
TH2_k127_5091486_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K04760 - - 0.0000000000000000000000000000000000000000001451 171.0
TH2_k127_5091486_9 transcriptional regulator - - - 0.0000000000000000000000000000000000226 143.0
TH2_k127_5094301_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.566e-243 767.0
TH2_k127_5094301_1 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 314.0
TH2_k127_5094301_2 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000006011 179.0
TH2_k127_5094301_4 TPR repeat - - - 0.0000000007464 67.0
TH2_k127_5117311_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1242.0
TH2_k127_5117311_1 nitrite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 405.0
TH2_k127_5117311_10 Putative zinc ribbon domain - - - 0.0000000000000003489 82.0
TH2_k127_5117311_11 CBS domain K04767,K07168,K07182 - - 0.00000004199 65.0
TH2_k127_5117311_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 427.0
TH2_k127_5117311_3 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 319.0
TH2_k127_5117311_4 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 322.0
TH2_k127_5117311_5 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 300.0
TH2_k127_5117311_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000003391 195.0
TH2_k127_5117311_8 nitrite reductase [NAD(P)H] activity K08355 - 1.20.2.1,1.20.9.1 0.000000000000000000000000000000000000000000000000001847 196.0
TH2_k127_5117311_9 Predicted membrane protein (DUF2238) - - - 0.00000000000000000000000000000000000000002162 161.0
TH2_k127_5117849_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 596.0
TH2_k127_5117849_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 434.0
TH2_k127_5117849_2 Domain of unknown function (DUF1736) - - - 0.000000000000000000000000004508 127.0
TH2_k127_51349_0 Peptidase dimerisation domain - - - 6.025e-224 734.0
TH2_k127_51349_1 Amidohydrolase family K05603 - 3.5.3.13 1.125e-216 698.0
TH2_k127_51349_10 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005594 264.0
TH2_k127_51349_11 Pfam:Methyltransf_26 - - - 0.00000000000000000000000000000000000000000000000000000000000009647 220.0
TH2_k127_51349_12 HutD K09975 - - 0.0000000000000000000000000000000000000000000000000000000000008035 216.0
TH2_k127_51349_14 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000002072 174.0
TH2_k127_51349_15 - - - - 0.000000000000000000000000000000000000008884 149.0
TH2_k127_51349_16 Esterase-like activity of phytase - - - 0.0000000000000000000000000000000000001716 155.0
TH2_k127_51349_17 Heavy-metal resistance - - - 0.00000000000000000000000000000003381 133.0
TH2_k127_51349_18 heat shock protein binding - - - 0.0000000000000000000000000001469 123.0
TH2_k127_51349_19 Stigma-specific protein, Stig1 - - - 0.0000000000000000000002598 109.0
TH2_k127_51349_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 3.708e-216 694.0
TH2_k127_51349_20 thiolester hydrolase activity - - - 0.0000000000001838 85.0
TH2_k127_51349_21 NmrA-like family - - - 0.000000000005954 74.0
TH2_k127_51349_3 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 601.0
TH2_k127_51349_4 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 427.0
TH2_k127_51349_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 383.0
TH2_k127_51349_6 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 329.0
TH2_k127_51349_7 Conserved TM helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004475 280.0
TH2_k127_51349_8 Protein of unknown function (DUF3095) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005793 281.0
TH2_k127_51349_9 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001143 267.0
TH2_k127_5143396_0 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000007419 215.0
TH2_k127_5143396_1 Transposase - - - 0.0000000000000000000000002217 111.0
TH2_k127_5143396_2 - - - - 0.0000000000000001406 87.0
TH2_k127_51772_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 475.0
TH2_k127_51772_1 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 310.0
TH2_k127_51772_2 PFAM Squalene phytoene synthase K02291,K21678,K21679 - 2.5.1.103,2.5.1.32,2.5.1.99,4.2.3.156 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002194 287.0
TH2_k127_51772_3 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000003049 194.0
TH2_k127_51772_4 Hydroxymethylglutaryl-coenzyme A reductase K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000007303 183.0
TH2_k127_51772_5 GHMP kinases N terminal domain K00938 - 2.7.4.2 0.0000000000000000000000000000004377 141.0
TH2_k127_51772_6 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00007463 45.0
TH2_k127_5192741_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 469.0
TH2_k127_5192741_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 342.0
TH2_k127_5192741_10 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000004104 142.0
TH2_k127_5192741_2 Protein of unknown function (DUF790) K09744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001692 293.0
TH2_k127_5192741_3 FAD binding domain K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001899 289.0
TH2_k127_5192741_4 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000002091 271.0
TH2_k127_5192741_5 Belongs to the SUA5 family K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000001475 246.0
TH2_k127_5192741_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000002319 246.0
TH2_k127_5192741_7 Type III restriction enzyme, res subunit - - - 0.000000000000000000000000000000000000004264 149.0
TH2_k127_5192741_8 SMART protein phosphatase 2C domain protein - - - 0.00000000000000000000000000000000000001323 162.0
TH2_k127_5192741_9 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000001662 145.0
TH2_k127_519362_0 Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 505.0
TH2_k127_519362_1 adenosine deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 496.0
TH2_k127_519362_2 RNA polymerase K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003491 266.0
TH2_k127_519362_3 Putative bacterial sensory transduction regulator - - - 0.0000000000000000000000000000000000000006372 158.0
TH2_k127_519362_4 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000004016 153.0
TH2_k127_519362_5 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000221 93.0
TH2_k127_5255295_0 SMART serine threonine protein kinase - - - 5.277e-259 827.0
TH2_k127_5255295_1 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 619.0
TH2_k127_5255295_10 carboxylic ester hydrolase activity - - - 0.0000002242 56.0
TH2_k127_5255295_11 Phage integrase family - - - 0.0000008978 54.0
TH2_k127_5255295_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 474.0
TH2_k127_5255295_3 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001356 298.0
TH2_k127_5255295_4 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000003866 265.0
TH2_k127_5255295_5 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001294 268.0
TH2_k127_5255295_6 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002298 265.0
TH2_k127_5255295_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000005119 209.0
TH2_k127_5255295_8 Glutamine amidotransferases class-II - - - 0.000000000000000000000000000000000004149 150.0
TH2_k127_5255295_9 TfoX N-terminal domain K07343 - - 0.00000000000000000000000005918 111.0
TH2_k127_5262620_0 Baseplate J-like protein - - - 0.0 1099.0
TH2_k127_5262620_1 lysine 2,3-aminomutase K01843 - 5.4.3.2 4.948e-231 722.0
TH2_k127_5262620_10 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000001416 216.0
TH2_k127_5262620_11 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000005853 217.0
TH2_k127_5262620_13 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000002228 205.0
TH2_k127_5262620_14 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000003088 201.0
TH2_k127_5262620_15 - - - - 0.0000000000000000000000000000000000000000000000003291 178.0
TH2_k127_5262620_16 cell wall organization K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000008696 197.0
TH2_k127_5262620_17 Gene 25-like lysozyme K06903 - - 0.000000000000000000000000000000000000000000006704 170.0
TH2_k127_5262620_18 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000000007687 158.0
TH2_k127_5262620_19 histone H2A K63-linked ubiquitination K16922 - - 0.0000000000000000000000000000000000004044 153.0
TH2_k127_5262620_2 tail sheath protein K06907 - - 3.387e-220 687.0
TH2_k127_5262620_20 Protein of unknown function (DUF1257) - - - 0.000000000000000000000000000000000002062 141.0
TH2_k127_5262620_21 histone H2A K63-linked ubiquitination K07169,K08884,K11894,K12132 - 2.7.11.1 0.000000000000000000000000000001135 138.0
TH2_k127_5262620_22 TPM domain - - - 0.0000000000000000000000000004797 127.0
TH2_k127_5262620_23 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000004886 120.0
TH2_k127_5262620_25 protein homooligomerization K08884 - 2.7.11.1 0.0000000000000000000000002822 117.0
TH2_k127_5262620_26 T4-like virus tail tube protein gp19 - - - 0.00000000000000000007198 97.0
TH2_k127_5262620_27 Pfam:TPM K08988 - - 0.0000000000000001539 89.0
TH2_k127_5262620_29 Phage late control gene D protein (GPD) - - - 0.00000000000001655 85.0
TH2_k127_5262620_3 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 1.853e-201 644.0
TH2_k127_5262620_30 protein containing LysM domain - - - 0.00000000000116 81.0
TH2_k127_5262620_31 - - - - 0.000000000008874 66.0
TH2_k127_5262620_33 Protein of unknown function (DUF2997) - - - 0.0000000002409 63.0
TH2_k127_5262620_34 IucA IucC family - - - 0.00001523 56.0
TH2_k127_5262620_4 - - - - 7.172e-198 629.0
TH2_k127_5262620_5 tail sheath protein K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 617.0
TH2_k127_5262620_6 Phage tail protein (Tail_P2_I) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 355.0
TH2_k127_5262620_7 Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 332.0
TH2_k127_5262620_8 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 306.0
TH2_k127_5262620_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000008326 222.0
TH2_k127_5263748_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002347 282.0
TH2_k127_5263748_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000002525 243.0
TH2_k127_5263748_2 OmpA family K02557 - - 0.000000000000000000000000000000000000000000001141 183.0
TH2_k127_5263748_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000001701 115.0
TH2_k127_5263748_4 Domain of unknown function (DUF4332) - - - 0.0000000000000003499 88.0
TH2_k127_5278626_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 3.011e-302 931.0
TH2_k127_5314420_0 Uracil phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 299.0
TH2_k127_5314420_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001468 275.0
TH2_k127_5314420_2 Response regulator, receiver K02657,K20972 - - 0.00000000000000000000000000000000000000000000000000000000000002086 232.0
TH2_k127_5314420_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000695 218.0
TH2_k127_5314420_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000225 177.0
TH2_k127_5314420_5 Tetratricopeptide repeat - - - 0.000000000000000000007374 106.0
TH2_k127_5314420_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001743 79.0
TH2_k127_5314420_7 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000007352 78.0
TH2_k127_5314420_8 Von Willebrand factor type A K07114 - - 0.00000000009865 73.0
TH2_k127_5327704_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 508.0
TH2_k127_5327704_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 475.0
TH2_k127_5327704_10 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000008255 254.0
TH2_k127_5327704_11 Xanthine and CO dehydrogenases maturation factor XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000003565 201.0
TH2_k127_5327704_12 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000004496 183.0
TH2_k127_5327704_13 Acyltransferase family - - - 0.00000000000000000000000000000000000000000005856 176.0
TH2_k127_5327704_14 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000001638 127.0
TH2_k127_5327704_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000002085 79.0
TH2_k127_5327704_2 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 446.0
TH2_k127_5327704_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 441.0
TH2_k127_5327704_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 417.0
TH2_k127_5327704_5 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 419.0
TH2_k127_5327704_6 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 383.0
TH2_k127_5327704_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 387.0
TH2_k127_5327704_8 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 343.0
TH2_k127_5327704_9 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 319.0
TH2_k127_533425_0 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 322.0
TH2_k127_533425_1 Universal stress protein - - - 0.00000000000000000001858 96.0
TH2_k127_533425_2 23S rRNA-intervening sequence protein - - - 0.00000000000000162 82.0
TH2_k127_5348457_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 374.0
TH2_k127_5348457_1 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.000000000000000000000000000000000000000000000000006931 192.0
TH2_k127_5348457_2 Class ii aldolase K01628,K03077,K11216 - 2.7.1.189,4.1.2.17,5.1.3.4 0.0000000000000000000000000000000000000000000001523 191.0
TH2_k127_5348457_3 protein conserved in bacteria K09973 - - 0.0000000000000002513 85.0
TH2_k127_5352558_0 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 445.0
TH2_k127_5352558_1 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 402.0
TH2_k127_5352558_2 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000005577 257.0
TH2_k127_5352558_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000002903 240.0
TH2_k127_5352558_4 PHB/PHA accumulation regulator DNA-binding domain - - - 0.000000000000000000000000000000000000000000001693 171.0
TH2_k127_5352558_5 - - - - 0.000000000000000000000000000000000000005781 157.0
TH2_k127_5352558_6 - - - - 0.0000000000000000000000000000000002213 143.0
TH2_k127_5352558_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005794,GO:0005802,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0012505,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0031410,GO:0031982,GO:0031984,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0097708,GO:0098791,GO:0140096,GO:1901564 - 0.0000000000000000000000000002749 131.0
TH2_k127_5352558_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000002121 80.0
TH2_k127_5352558_9 Kelch motif - - - 0.0002728 52.0
TH2_k127_5393595_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000003116 175.0
TH2_k127_5393595_1 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000001046 153.0
TH2_k127_5393595_2 Fungalysin metallopeptidase (M36) - - - 0.00000001117 66.0
TH2_k127_5393595_3 - - - - 0.000009522 52.0
TH2_k127_5457415_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 481.0
TH2_k127_5457415_1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 445.0
TH2_k127_5457415_10 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000007834 196.0
TH2_k127_5457415_11 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000001859 142.0
TH2_k127_5457415_12 TRAP transporter T-component - - - 0.00000000000000000000000003787 121.0
TH2_k127_5457415_13 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000004506 97.0
TH2_k127_5457415_16 TRAP dicarboxylate transporter, DctQ subunit - - - 0.0001551 51.0
TH2_k127_5457415_2 FAD dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 439.0
TH2_k127_5457415_3 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 381.0
TH2_k127_5457415_4 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 370.0
TH2_k127_5457415_5 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 359.0
TH2_k127_5457415_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 329.0
TH2_k127_5457415_7 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004341 297.0
TH2_k127_5457415_8 Bacterial extracellular solute-binding protein, family 7 K11688,K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000008524 247.0
TH2_k127_5457415_9 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000001324 238.0
TH2_k127_5477400_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 627.0
TH2_k127_5477400_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 328.0
TH2_k127_5477400_2 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001149 246.0
TH2_k127_5500535_0 FHA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 363.0
TH2_k127_5500535_1 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 303.0
TH2_k127_5500535_2 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000001848 256.0
TH2_k127_5500535_5 PFAM PHA accumulation regulator DNA-binding protein - - - 0.0000000000395 71.0
TH2_k127_5575567_0 PrkA serine protein kinase C-terminal domain - - - 4.135e-262 827.0
TH2_k127_5575567_1 Insulinase (Peptidase family M16) K07263 - - 1.512e-216 717.0
TH2_k127_5575567_10 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 319.0
TH2_k127_5575567_11 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000238 285.0
TH2_k127_5575567_12 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001523 280.0
TH2_k127_5575567_13 Wzt C-terminal domain K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000443 259.0
TH2_k127_5575567_14 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003475 261.0
TH2_k127_5575567_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002746 263.0
TH2_k127_5575567_16 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000002626 250.0
TH2_k127_5575567_17 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000002452 244.0
TH2_k127_5575567_18 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000001458 208.0
TH2_k127_5575567_19 PQQ enzyme repeat K17713 - - 0.0000000000000000000000000000000000000000000000000003346 201.0
TH2_k127_5575567_2 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 591.0
TH2_k127_5575567_20 Methionine biosynthesis protein MetW K20444 - - 0.0000000000000000000000000000000000000000000000000006647 199.0
TH2_k127_5575567_21 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000009225 193.0
TH2_k127_5575567_22 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000001938 193.0
TH2_k127_5575567_23 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000005742 189.0
TH2_k127_5575567_24 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000002596 176.0
TH2_k127_5575567_25 Acyltransferase - - - 0.0000000000000000000000000000000000000000001647 172.0
TH2_k127_5575567_26 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000001086 170.0
TH2_k127_5575567_27 sugar transferase - - - 0.00000000000000000000000000000000000113 153.0
TH2_k127_5575567_28 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000009625 141.0
TH2_k127_5575567_29 Biopolymer transport protein K03559 - - 0.00000000000000000000000000000001549 141.0
TH2_k127_5575567_3 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 440.0
TH2_k127_5575567_30 PilZ domain - - - 0.00000000000000000000000000000006924 133.0
TH2_k127_5575567_31 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000209 131.0
TH2_k127_5575567_32 - - - - 0.00000000000000000006567 94.0
TH2_k127_5575567_34 repeat protein - - - 0.000000000000443 79.0
TH2_k127_5575567_37 PHB depolymerase family esterase - - - 0.0000001567 63.0
TH2_k127_5575567_39 TPR domain protein - - - 0.0003493 52.0
TH2_k127_5575567_4 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 427.0
TH2_k127_5575567_5 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 427.0
TH2_k127_5575567_6 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 408.0
TH2_k127_5575567_7 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 382.0
TH2_k127_5575567_8 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 349.0
TH2_k127_5575567_9 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 367.0
TH2_k127_5598950_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1116.0
TH2_k127_5598950_1 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 4.249e-207 652.0
TH2_k127_5598950_10 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000000000000000000000000000000000000000000001127 233.0
TH2_k127_5598950_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000008401 234.0
TH2_k127_5598950_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000001382 197.0
TH2_k127_5598950_14 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000001596 194.0
TH2_k127_5598950_15 response to oxidative stress - - - 0.0000000000000000000000000000000000000000005105 163.0
TH2_k127_5598950_16 Phosphate acyltransferases - - - 0.000000000000000000000000000000000485 151.0
TH2_k127_5598950_17 MatE K03327 - - 0.000000000000000000000000000001277 138.0
TH2_k127_5598950_18 PFAM Alcohol dehydrogenase, zinc-binding K00344 - 1.6.5.5 0.00000000000000000000000000002085 124.0
TH2_k127_5598950_19 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000001186 123.0
TH2_k127_5598950_2 Protein phosphatase 2A homologues, catalytic domain. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 595.0
TH2_k127_5598950_20 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000007415 109.0
TH2_k127_5598950_21 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000005131 113.0
TH2_k127_5598950_22 Belongs to the BolA IbaG family - - - 0.00000000000000000001998 102.0
TH2_k127_5598950_23 AI-2E family transporter - - - 0.0001746 48.0
TH2_k127_5598950_3 short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 519.0
TH2_k127_5598950_4 tRNA synthetases class I (W and Y) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 479.0
TH2_k127_5598950_5 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 428.0
TH2_k127_5598950_7 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 316.0
TH2_k127_5598950_8 Organic Anion Transporter Polypeptide (OATP) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 304.0
TH2_k127_5598950_9 Acetyl-coenzyme A transporter 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001872 299.0
TH2_k127_5611016_0 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 432.0
TH2_k127_5611016_1 Outer membrane component of multidrug efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 387.0
TH2_k127_5611016_10 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000001354 202.0
TH2_k127_5611016_11 - - - - 0.00000000000000000000000000000000000000000000407 179.0
TH2_k127_5611016_12 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.000000000000000000000000000000000000000005371 157.0
TH2_k127_5611016_13 Adenylylsulfate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000001436 164.0
TH2_k127_5611016_14 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000005755 175.0
TH2_k127_5611016_15 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000002078 141.0
TH2_k127_5611016_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000003212 140.0
TH2_k127_5611016_17 PFAM GGDEF domain containing protein K02488 - 2.7.7.65 0.0000000000000000000000000000000007338 145.0
TH2_k127_5611016_18 YceI-like domain - - - 0.0000000000000000000000000000001325 130.0
TH2_k127_5611016_19 cellulose binding - - - 0.0000000000000000000000000002235 127.0
TH2_k127_5611016_2 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 361.0
TH2_k127_5611016_20 CBS domain K04767,K07168,K07182 - - 0.000000000000000000000006108 106.0
TH2_k127_5611016_21 oxidoreductase activity K07114 - - 0.000000000000000005517 96.0
TH2_k127_5611016_22 epimerase dehydratase K01784 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 5.1.3.2 0.00000000000000005682 94.0
TH2_k127_5611016_23 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000003938 76.0
TH2_k127_5611016_24 - - - - 0.00000000000005382 78.0
TH2_k127_5611016_25 TPR repeat - - - 0.0000000002654 71.0
TH2_k127_5611016_26 Cbs domain - - - 0.000000003631 67.0
TH2_k127_5611016_27 NapC/NirT cytochrome c family, N-terminal region K03532 - - 0.0008503 49.0
TH2_k127_5611016_3 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 330.0
TH2_k127_5611016_4 RNA polymerase K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001348 298.0
TH2_k127_5611016_5 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002107 283.0
TH2_k127_5611016_6 COG0845 membrane-fusion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006146 256.0
TH2_k127_5611016_7 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000007018 250.0
TH2_k127_5611016_8 Calcineurin-like phosphoesterase K14379 - 3.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000004956 239.0
TH2_k127_5617503_0 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000005595 169.0
TH2_k127_5617503_1 Membrane - - - 0.0000001396 64.0
TH2_k127_5617503_2 CARDB - - - 0.0004222 53.0
TH2_k127_5638795_0 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 537.0
TH2_k127_5638795_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 506.0
TH2_k127_5638795_10 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 0.00000000000000000000000002335 112.0
TH2_k127_5638795_11 Belongs to the GSP D family K02280 - - 0.0000000000000000000000004182 114.0
TH2_k127_5638795_12 - - - - 0.00000000000000000005616 97.0
TH2_k127_5638795_13 PFAM Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.00000000000000004332 89.0
TH2_k127_5638795_14 Belongs to the ompA family K20276 - - 0.0000003764 62.0
TH2_k127_5638795_15 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000005034 61.0
TH2_k127_5638795_16 Histidyl-tRNA synthetase - - - 0.000004563 61.0
TH2_k127_5638795_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 424.0
TH2_k127_5638795_3 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 431.0
TH2_k127_5638795_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 385.0
TH2_k127_5638795_5 Cellulase (glycosyl hydrolase family 5) K19355 - 3.2.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009472 371.0
TH2_k127_5638795_6 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000838 266.0
TH2_k127_5638795_7 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000001357 241.0
TH2_k127_5638795_8 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000001523 212.0
TH2_k127_5638795_9 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.4.2.9 0.0000000000000000000000000000000000000000000000001551 187.0
TH2_k127_5654070_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 603.0
TH2_k127_5654070_1 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 455.0
TH2_k127_5654070_2 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.00000000000000000000000000000000000000000000000000000000000007524 223.0
TH2_k127_5654070_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000002422 152.0
TH2_k127_5654070_4 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000005597 117.0
TH2_k127_565417_0 Transcriptional regulator - - - 1.735e-225 713.0
TH2_k127_565417_1 DbpA RNA binding domain K03732,K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 393.0
TH2_k127_565417_2 Tetratricopeptide repeat - - - 0.000000000000000007764 94.0
TH2_k127_565417_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000001673 71.0
TH2_k127_568208_0 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 439.0
TH2_k127_568208_1 Gluconokinase K00851 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0046316 2.7.1.12 0.0000000000000000000000000000000000000009999 151.0
TH2_k127_5693515_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 383.0
TH2_k127_5693515_1 Bestrophin, RFP-TM, chloride channel K08994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 321.0
TH2_k127_5693515_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000007092 243.0
TH2_k127_5693515_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000006404 241.0
TH2_k127_5693515_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000003054 222.0
TH2_k127_5693515_5 RNA-DNA hybrid ribonuclease activity K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000002834 195.0
TH2_k127_5693515_6 TPR repeat - - - 0.0000112 53.0
TH2_k127_5700384_0 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 456.0
TH2_k127_5700384_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 315.0
TH2_k127_5700384_2 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001502 236.0
TH2_k127_5712039_0 Beta-eliminating lyase K01667 - 4.1.99.1 2.007e-273 847.0
TH2_k127_5712039_1 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 480.0
TH2_k127_5712039_10 Trypsin-like serine protease - - - 0.0000001398 63.0
TH2_k127_5712039_12 peptidyl-tyrosine sulfation - - - 0.00008575 52.0
TH2_k127_5712039_13 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0001368 47.0
TH2_k127_5712039_14 EB module - - - 0.0005623 44.0
TH2_k127_5712039_2 1,4-alpha-D-glucan glucohydrolase K01178 GO:0000272,GO:0000322,GO:0000323,GO:0000324,GO:0003674,GO:0003824,GO:0004339,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009986,GO:0009987,GO:0015926,GO:0015980,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704,GO:1901575 3.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000118 235.0
TH2_k127_5712039_3 cellulose binding - - - 0.00000000000000000000000000000000000000000000000001323 192.0
TH2_k127_5712039_4 xylanase chitin deacetylase K22278 - 3.5.1.104 0.00000000000000000000000003286 118.0
TH2_k127_5712039_6 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000001254 96.0
TH2_k127_5712039_7 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000001145 81.0
TH2_k127_5712039_8 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000008332 80.0
TH2_k127_5712039_9 - - - - 0.00000000163 66.0
TH2_k127_5712040_0 enzyme of poly-gamma-glutamate biosynthesis (Capsule formation) K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002596 265.0
TH2_k127_5712040_1 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002561 263.0
TH2_k127_5712040_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000001439 145.0
TH2_k127_5712040_3 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000006059 126.0
TH2_k127_5712042_0 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 593.0
TH2_k127_5712042_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 598.0
TH2_k127_5712042_2 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 431.0
TH2_k127_5712042_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008804 416.0
TH2_k127_5712042_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 395.0
TH2_k127_5712042_5 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 327.0
TH2_k127_5712042_6 cobalamin binding K03496,K22491 - - 0.0000000000000000000000000000000000000000000000000000000001635 213.0
TH2_k127_5712042_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000003689 160.0
TH2_k127_5712042_8 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000004346 54.0
TH2_k127_5712043_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 6.202e-203 657.0
TH2_k127_5712043_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 375.0
TH2_k127_5712043_2 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000001864 177.0
TH2_k127_5712500_0 Bacterial regulatory protein, Fis family K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 620.0
TH2_k127_5712500_1 peptidase U62 modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 555.0
TH2_k127_5712500_10 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005894 267.0
TH2_k127_5712500_11 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000004182 252.0
TH2_k127_5712500_12 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000004637 236.0
TH2_k127_5712500_13 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000008018 214.0
TH2_k127_5712500_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000135 223.0
TH2_k127_5712500_15 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000001384 207.0
TH2_k127_5712500_16 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000001265 216.0
TH2_k127_5712500_17 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000005516 198.0
TH2_k127_5712500_18 EVE domain - - - 0.0000000000000000000000000000000000000000000000001682 184.0
TH2_k127_5712500_19 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000004092 158.0
TH2_k127_5712500_2 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412,K03224 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 492.0
TH2_k127_5712500_20 Calcium-binding EGF domain - - - 0.000000000000000000000000000000000001051 158.0
TH2_k127_5712500_21 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000003652 130.0
TH2_k127_5712500_22 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000009788 126.0
TH2_k127_5712500_23 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000006422 127.0
TH2_k127_5712500_24 Universal stress protein family - - - 0.00000000000000000000000001802 115.0
TH2_k127_5712500_25 TPM domain - - - 0.00000000000000000000000002447 122.0
TH2_k127_5712500_26 - - - - 0.0000000000000000000000005834 118.0
TH2_k127_5712500_27 Universal stress protein family - - - 0.0000000000000000000005977 103.0
TH2_k127_5712500_28 - - - - 0.000000000000000000001133 101.0
TH2_k127_5712500_29 protein conserved in archaea - - - 0.00000000000000000003444 104.0
TH2_k127_5712500_3 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 470.0
TH2_k127_5712500_30 PilZ domain - - - 0.0000000000000000001344 100.0
TH2_k127_5712500_31 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000003096 82.0
TH2_k127_5712500_32 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000002488 79.0
TH2_k127_5712500_33 Protein of unknown function (DUF3570) - - - 0.0000000000001202 81.0
TH2_k127_5712500_34 COG1317 Flagellar biosynthesis type III secretory pathway protein K02411 - - 0.000000000001145 79.0
TH2_k127_5712500_35 Endonuclease Exonuclease phosphatase - - - 0.0000000002347 72.0
TH2_k127_5712500_36 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.0000000003311 63.0
TH2_k127_5712500_38 tRNA wobble adenosine to inosine editing - - - 0.0000000041 61.0
TH2_k127_5712500_39 Tetratricopeptide repeat - - - 0.0000001976 62.0
TH2_k127_5712500_4 PFAM AMP-dependent synthetase and ligase K04110 - 6.2.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 400.0
TH2_k127_5712500_40 - - - - 0.0000009177 61.0
TH2_k127_5712500_5 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 373.0
TH2_k127_5712500_6 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000879 346.0
TH2_k127_5712500_7 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 312.0
TH2_k127_5712500_8 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 295.0
TH2_k127_5712500_9 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000652 304.0
TH2_k127_5719513_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 470.0
TH2_k127_5719513_1 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 342.0
TH2_k127_5719513_2 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 358.0
TH2_k127_5719513_3 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000005086 173.0
TH2_k127_5719513_4 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000000000001716 138.0
TH2_k127_5719513_5 transferase activity, transferring amino-acyl groups - - - 0.000000000000000000000000002449 126.0
TH2_k127_5719513_6 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000001656 63.0
TH2_k127_5719873_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 561.0
TH2_k127_5719873_1 PFAM PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 305.0
TH2_k127_5719873_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004535 258.0
TH2_k127_5719873_3 TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007752 256.0
TH2_k127_5719873_5 Sulfotransferase domain - - - 0.0000881 56.0
TH2_k127_5728524_0 UvrD-like helicase C-terminal domain K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 360.0
TH2_k127_5728524_1 metallopeptidase activity K01183 - 3.2.1.14 0.00000000000000000000000000203 128.0
TH2_k127_5728524_2 Extensin-like protein C-terminus - - - 0.0001312 54.0
TH2_k127_5730023_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 459.0
TH2_k127_5730023_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 396.0
TH2_k127_5730023_10 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000392 216.0
TH2_k127_5730023_12 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.00000000000000000000000000000000000000000003038 177.0
TH2_k127_5730023_13 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000001606 164.0
TH2_k127_5730023_14 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000008192 141.0
TH2_k127_5730023_15 serine-type endopeptidase activity - - - 0.00000000000000000000000000000004091 137.0
TH2_k127_5730023_17 FHA domain - - - 0.000000000000000000000008432 108.0
TH2_k127_5730023_18 - - - - 0.00000000000000002597 96.0
TH2_k127_5730023_19 outer membrane efflux protein K03287 - - 0.00000000004041 76.0
TH2_k127_5730023_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 348.0
TH2_k127_5730023_20 Esterase PHB depolymerase K03932 - - 0.00000005262 64.0
TH2_k127_5730023_21 TPR repeat - - - 0.000001176 60.0
TH2_k127_5730023_3 ABC-type multidrug transport system ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 364.0
TH2_k127_5730023_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 321.0
TH2_k127_5730023_5 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 310.0
TH2_k127_5730023_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 311.0
TH2_k127_5730023_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002378 274.0
TH2_k127_5730023_8 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003988 275.0
TH2_k127_5730023_9 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000001283 212.0
TH2_k127_575327_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 532.0
TH2_k127_575327_1 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000005338 177.0
TH2_k127_575327_2 flagellar motor protein K02557 - - 0.0000000000000000000000001147 114.0
TH2_k127_575327_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.0000000000000000000007151 102.0
TH2_k127_575327_4 peptide transport - - - 0.0003393 54.0
TH2_k127_5758700_0 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 478.0
TH2_k127_5758700_1 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009176 387.0
TH2_k127_5758700_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 324.0
TH2_k127_5758700_3 Beta-ketoacyl synthase, C-terminal domain K05551,K09458 - 2.3.1.179,2.3.1.235,2.3.1.260 0.0000000000000000000000000000198 128.0
TH2_k127_5765861_0 SNF2 family N-terminal domain - - - 6.385e-233 737.0
TH2_k127_5765861_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 599.0
TH2_k127_5765861_2 DNA-(Apurinic or apyrimidinic site) lyase K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 461.0
TH2_k127_5765861_3 Alanine dehydrogenase/PNT, C-terminal domain K00324 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 454.0
TH2_k127_5765861_5 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000001358 231.0
TH2_k127_5765861_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000001444 164.0
TH2_k127_5765861_7 oligosaccharyl transferase activity - - - 0.0000000000000000000006169 111.0
TH2_k127_5765861_8 PFAM CBS domain containing protein - - - 0.0000000000000000009176 91.0
TH2_k127_5765861_9 PilZ domain - - - 0.0007315 52.0
TH2_k127_5766067_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 8.484e-215 676.0
TH2_k127_5766067_1 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 582.0
TH2_k127_5766067_10 Binds the 23S rRNA K02909 - - 0.0000000000000000001554 97.0
TH2_k127_5766067_11 PFAM methyltransferase - - - 0.000000001389 71.0
TH2_k127_5766067_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 372.0
TH2_k127_5766067_3 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 312.0
TH2_k127_5766067_4 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004148 292.0
TH2_k127_5766067_5 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000005117 203.0
TH2_k127_5766067_6 PFAM regulatory protein TetR K13770 - - 0.000000000000000000000000000000000000000000000000009263 188.0
TH2_k127_5766067_7 Thioredoxin - - - 0.0000000000000000000000000000000000000000003179 170.0
TH2_k127_5766067_8 cell redox homeostasis K00384 - 1.8.1.9 0.00000000000000000000000000003002 123.0
TH2_k127_5766067_9 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000002057 112.0
TH2_k127_580175_0 Alcohol dehydrogenase GroES-like domain K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004442 254.0
TH2_k127_580175_1 - - - - 0.00003364 50.0
TH2_k127_5812823_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 425.0
TH2_k127_5812823_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 299.0
TH2_k127_5812823_10 SPTR Thioredoxin family protein - - - 0.000000000000001488 88.0
TH2_k127_5812823_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000002153 84.0
TH2_k127_5812823_12 Probable zinc-ribbon domain - - - 0.0000000002711 66.0
TH2_k127_5812823_13 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000005577 71.0
TH2_k127_5812823_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.000000006676 68.0
TH2_k127_5812823_15 COG0457 FOG TPR repeat - - - 0.00000005712 64.0
TH2_k127_5812823_16 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000004447 61.0
TH2_k127_5812823_2 of the major facilitator superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007747 306.0
TH2_k127_5812823_3 PspA/IM30 family K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 286.0
TH2_k127_5812823_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000004102 269.0
TH2_k127_5812823_5 SMART serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000004253 237.0
TH2_k127_5812823_6 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000008426 209.0
TH2_k127_5812823_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000002031 202.0
TH2_k127_5812823_8 PilZ domain - - - 0.00000000000000000000000000001299 126.0
TH2_k127_5812823_9 - - - - 0.000000000000000000000001126 109.0
TH2_k127_5826587_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 402.0
TH2_k127_5826587_1 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000003966 207.0
TH2_k127_5826587_2 Conserved Protein - GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000003109 95.0
TH2_k127_5829778_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 431.0
TH2_k127_5829778_1 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.290 0.000000000000000000000000000000000000005851 150.0
TH2_k127_5829778_2 - - - - 0.000000000000000000004326 104.0
TH2_k127_5829808_0 Uncharacterised protein family (UPF0158) - - - 0.000000000000000000000000000000000000000000000000000000000000000000124 237.0
TH2_k127_5829808_1 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000007565 105.0
TH2_k127_585660_0 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000002511 231.0
TH2_k127_585660_1 Type IV pilus assembly protein PilM; K02461 - - 0.0000000000000000000000000000000000000000000000000000000001369 224.0
TH2_k127_585660_2 Type II secretion system (T2SS), protein J K02459 - - 0.0000000000000000000000000000000000000002459 162.0
TH2_k127_585660_3 Prokaryotic N-terminal methylation motif K02457 - - 0.00000000000000000000004317 111.0
TH2_k127_585660_4 - - - - 0.00000000000000000001671 104.0
TH2_k127_585660_6 Prokaryotic N-terminal methylation motif K02458 - - 0.0000000000001136 82.0
TH2_k127_585660_7 General secretion pathway protein - - - 0.000000001856 61.0
TH2_k127_5868034_0 oligopeptide transporter, OPT family - - - 2.877e-286 895.0
TH2_k127_5868034_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 516.0
TH2_k127_5868034_10 - - - - 0.00000000000000000000000000000000000000002723 160.0
TH2_k127_5868034_11 - - - - 0.000000000000000000000000000000000000004901 161.0
TH2_k127_5868034_12 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000000000000001321 104.0
TH2_k127_5868034_13 PFAM Integrase catalytic - - - 0.000000000000000003362 89.0
TH2_k127_5868034_14 DsrC like protein K11179 - - 0.000000000000000005317 96.0
TH2_k127_5868034_15 DNA-binding transcription factor activity K03892,K22298 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0010045,GO:0032025,GO:0042221,GO:0050896,GO:0097159,GO:1901363 - 0.000000000000001413 80.0
TH2_k127_5868034_17 Adenylate cyclase - - - 0.000000000001529 82.0
TH2_k127_5868034_18 Glycosyl hydrolases family 16 K08254 - 3.2.1.59 0.00000000001644 77.0
TH2_k127_5868034_19 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.0000002489 60.0
TH2_k127_5868034_2 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000455 250.0
TH2_k127_5868034_20 DDE superfamily endonuclease - - - 0.00002025 51.0
TH2_k127_5868034_3 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005287 241.0
TH2_k127_5868034_4 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000007701 221.0
TH2_k127_5868034_5 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000002322 228.0
TH2_k127_5868034_6 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000004803 205.0
TH2_k127_5868034_7 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000002835 181.0
TH2_k127_5868034_8 - - - - 0.00000000000000000000000000000000000000000002479 186.0
TH2_k127_5868034_9 Glutaredoxin - - - 0.0000000000000000000000000000000000000000001191 164.0
TH2_k127_587789_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 544.0
TH2_k127_587789_1 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 507.0
TH2_k127_587789_2 TonB dependent receptor K02014 - - 0.0000000005388 70.0
TH2_k127_5882572_0 Vault protein inter-alpha-trypsin domain - - - 4.026e-253 818.0
TH2_k127_5882572_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.148e-239 753.0
TH2_k127_5882572_2 Type II/IV secretion system protein K02454,K02652 - - 2.528e-229 733.0
TH2_k127_5882572_3 Malic enzyme, N-terminal domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 406.0
TH2_k127_5882572_4 Acyltransferase family K16568 - - 0.0000000000000000000000000000000000000000000000000000000000000002379 234.0
TH2_k127_5882572_5 EGF domain - - - 0.0000000000000000000000000000000000000006943 167.0
TH2_k127_5882572_6 resolution of meiotic recombination intermediates - - - 0.00000000000000000000000000004875 136.0
TH2_k127_5882572_7 MSP1 EGF domain 1 K17307 - - 0.00000000000004414 85.0
TH2_k127_588651_0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 530.0
TH2_k127_588651_1 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 442.0
TH2_k127_588651_10 Outer membrane lipoprotein-sorting protein - - - 0.00000000000001299 85.0
TH2_k127_588651_2 Pfam:Kce K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 430.0
TH2_k127_588651_3 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 297.0
TH2_k127_588651_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005853 273.0
TH2_k127_588651_5 growth of symbiont in host cell K07003 - - 0.0000000000000000000000000000000000000000000000000000000000004442 241.0
TH2_k127_588651_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000005356 189.0
TH2_k127_588651_7 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000003198 116.0
TH2_k127_588651_8 Tetratricopeptide repeat - - - 0.000000000000000000007141 108.0
TH2_k127_588651_9 regulation of translation K03530,K05788 - - 0.00000000000000000000732 101.0
TH2_k127_5974052_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 406.0
TH2_k127_5974052_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 308.0
TH2_k127_5974052_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003323 274.0
TH2_k127_5974052_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000002289 213.0
TH2_k127_5974052_4 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000003425 218.0
TH2_k127_5974052_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000006264 193.0
TH2_k127_5974052_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000001266 98.0
TH2_k127_5974052_7 Domain of unknown function (DUF4340) - - - 0.0000000000000005342 93.0
TH2_k127_5974052_8 TRAM domain K03215 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 0.0000000000000007121 82.0
TH2_k127_5994383_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 584.0
TH2_k127_5994383_1 Belongs to the ClpX chaperone family K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 518.0
TH2_k127_5994383_10 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000006701 119.0
TH2_k127_5994383_11 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000006141 88.0
TH2_k127_5994383_14 COG0666 FOG Ankyrin repeat K06867 - - 0.00000000000006227 85.0
TH2_k127_5994383_15 - - - - 0.00005842 50.0
TH2_k127_5994383_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 497.0
TH2_k127_5994383_3 Type III secretion protein K03230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 381.0
TH2_k127_5994383_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 327.0
TH2_k127_5994383_5 Inhibitor of apoptosis-promoting Bax1 K06890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009852 256.0
TH2_k127_5994383_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000002129 261.0
TH2_k127_5994383_7 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000005723 212.0
TH2_k127_5994383_9 - - - - 0.0000000000000000000000000008118 124.0
TH2_k127_6001609_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 5.429e-259 831.0
TH2_k127_6001609_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 446.0
TH2_k127_6001609_10 redox protein regulator of disulfide bond formation - - - 0.000000000000002903 83.0
TH2_k127_6001609_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000002301 79.0
TH2_k127_6001609_12 23S rRNA-intervening sequence protein - - - 0.00000004563 59.0
TH2_k127_6001609_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.000001164 51.0
TH2_k127_6001609_14 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000002505 59.0
TH2_k127_6001609_16 23S rRNA-intervening sequence protein - - - 0.00008979 50.0
TH2_k127_6001609_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 453.0
TH2_k127_6001609_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 316.0
TH2_k127_6001609_4 K transport systems K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001139 278.0
TH2_k127_6001609_5 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000001545 239.0
TH2_k127_6001609_6 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.0000000000000000000000000000000000000000000000000000000006269 207.0
TH2_k127_6001609_7 Universal stress protein - - - 0.0000000000000000000000000000000004205 139.0
TH2_k127_6001609_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000007717 116.0
TH2_k127_6001609_9 Protein of unknown function (DUF2892) - - - 0.00000000000000000001286 94.0
TH2_k127_6001773_0 Tetratricopeptide repeat - - - 6.665e-226 743.0
TH2_k127_6001773_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 484.0
TH2_k127_6001773_10 RDD family - - - 0.00000000000001554 81.0
TH2_k127_6001773_11 - - - - 0.00000000009225 67.0
TH2_k127_6001773_2 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 296.0
TH2_k127_6001773_3 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001694 304.0
TH2_k127_6001773_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000005168 202.0
TH2_k127_6001773_5 adventurous gliding protein T - - - 0.0000000000000000000000000000000000000000002479 176.0
TH2_k127_6001773_6 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000004666 175.0
TH2_k127_6001773_7 FHA domain - - - 0.0000000000000000000000000000000000000000005867 161.0
TH2_k127_6001773_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.00000000000000000000000000000000007611 145.0
TH2_k127_6001773_9 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000005651 87.0
TH2_k127_6006995_0 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000004502 132.0
TH2_k127_6006995_1 geranylgeranyl reductase activity - - - 0.00000000003912 70.0
TH2_k127_6006995_2 EamA-like transporter family - - - 0.000007772 53.0
TH2_k127_6017662_0 Transporter K03305 - - 1.696e-208 661.0
TH2_k127_6017662_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 516.0
TH2_k127_6017662_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 439.0
TH2_k127_6017662_3 Transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 362.0
TH2_k127_6017662_4 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002314 263.0
TH2_k127_6017662_5 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000002755 250.0
TH2_k127_6017662_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000001864 76.0
TH2_k127_6018739_0 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.000000000000000000000000000000000000000000000000000000000007649 219.0
TH2_k127_6018739_1 epimerase K00091,K01007,K02377,K07118,K19073,K19267 - 1.1.1.219,1.1.1.271,1.3.1.75,1.6.5.2,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000001903 214.0
TH2_k127_6018739_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000008614 108.0
TH2_k127_6025545_0 DNA helicase K03656,K03657 - 3.6.4.12 6.638e-199 652.0
TH2_k127_6025545_1 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 400.0
TH2_k127_6025545_10 - - - - 0.00000000000000000000000000000000000000000002959 168.0
TH2_k127_6025545_11 SMART helicase c2 K03722 - 3.6.4.12 0.000000000000000000000000000000000008969 144.0
TH2_k127_6025545_13 protein involved in exopolysaccharide biosynthesis K16554 - - 0.00002597 51.0
TH2_k127_6025545_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 334.0
TH2_k127_6025545_3 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 351.0
TH2_k127_6025545_4 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000002359 241.0
TH2_k127_6025545_5 Bacterial transferase hexapeptide - - - 0.00000000000000000000000000000000000000000000000000000000000009907 223.0
TH2_k127_6025545_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000003898 212.0
TH2_k127_6025545_7 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000002299 194.0
TH2_k127_6025545_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000008052 187.0
TH2_k127_6025545_9 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000512 186.0
TH2_k127_602655_0 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 506.0
TH2_k127_602655_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 325.0
TH2_k127_602655_2 Serine Threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001703 267.0
TH2_k127_602655_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000001107 224.0
TH2_k127_6058784_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 471.0
TH2_k127_6058784_1 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 374.0
TH2_k127_6058784_2 MgsA AAA+ ATPase C terminal K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000007137 53.0
TH2_k127_6111105_0 repeat protein - - - 1.013e-199 679.0
TH2_k127_6111105_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 597.0
TH2_k127_6111105_10 COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA K06169 - - 0.00000000000000000000000000000002171 142.0
TH2_k127_6111105_11 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000006901 119.0
TH2_k127_6111105_12 N-terminal half of MaoC dehydratase - - - 0.000000000000000000002809 104.0
TH2_k127_6111105_13 bacterial-type flagellum-dependent cell motility - - - 0.00000004568 64.0
TH2_k127_6111105_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 393.0
TH2_k127_6111105_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 373.0
TH2_k127_6111105_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 348.0
TH2_k127_6111105_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001441 273.0
TH2_k127_6111105_6 Belongs to the phosphatidylserine decarboxylase family K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000008986 258.0
TH2_k127_6111105_7 MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004951 267.0
TH2_k127_6111105_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000001256 222.0
TH2_k127_6111105_9 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000003426 205.0
TH2_k127_614396_0 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008549 563.0
TH2_k127_614396_1 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009278 573.0
TH2_k127_614396_10 Pfam Major Facilitator Superfamily - - - 0.000000000000000000000001907 104.0
TH2_k127_614396_11 PFAM transposase IS3 IS911 family protein K07483 - - 0.00000000000000000000006646 102.0
TH2_k127_614396_12 Transcriptional regulator antitoxin, MazE K07172 - - 0.00000000000000002358 84.0
TH2_k127_614396_13 Redoxin domain protein - - - 0.00000000000000005 96.0
TH2_k127_614396_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 338.0
TH2_k127_614396_3 HTH-like domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003824 278.0
TH2_k127_614396_4 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000149 294.0
TH2_k127_614396_5 Two component transcriptional regulator, winged helix family K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002161 256.0
TH2_k127_614396_6 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000005024 259.0
TH2_k127_614396_7 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000542 215.0
TH2_k127_614396_8 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000005345 187.0
TH2_k127_614396_9 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000000003051 167.0
TH2_k127_6153817_0 synthase K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 481.0
TH2_k127_6153817_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 443.0
TH2_k127_6153817_2 DTW - - - 0.00000000000000000000000000000000000001628 153.0
TH2_k127_6153817_3 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000007125 121.0
TH2_k127_6153817_4 Belongs to the phospholipase D family. Cardiolipin synthase subfamily K06131 - - 0.00000000000000000004696 105.0
TH2_k127_6153817_5 sporulation resulting in formation of a cellular spore K06381 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.00000000000006637 79.0
TH2_k127_6153817_6 TPR repeat - - - 0.00000000001365 76.0
TH2_k127_6188439_0 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 483.0
TH2_k127_6188439_1 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002988 286.0
TH2_k127_620289_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 362.0
TH2_k127_620289_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000006048 243.0
TH2_k127_620289_2 E1-E2 ATPase K12949,K12956,K17686 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0042221,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046688,GO:0050896,GO:0051704,GO:0071944 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000007251 233.0
TH2_k127_620289_3 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001214 215.0
TH2_k127_620289_4 domain protein - - - 0.00000000000000000000001388 105.0
TH2_k127_620289_5 Cytochrome C assembly protein - - - 0.00000000000000000001032 103.0
TH2_k127_620289_6 - - - - 0.0000000000000000008479 89.0
TH2_k127_6204510_0 Peptidase dimerisation domain - - - 8.753e-221 692.0
TH2_k127_6204510_1 Transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 556.0
TH2_k127_6204510_10 Prokaryotic N-terminal methylation motif K02650 - - 0.00000003441 66.0
TH2_k127_6204510_2 protein conserved in bacteria K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 327.0
TH2_k127_6204510_3 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 310.0
TH2_k127_6204510_4 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003651 249.0
TH2_k127_6204510_5 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000007165 204.0
TH2_k127_6204510_6 Putative DNA-binding domain - - - 0.000000000000000000000000000000006243 145.0
TH2_k127_6204510_7 AMP binding - GO:0008150,GO:0040007 - 0.0000000000000000000002104 102.0
TH2_k127_6204510_8 - K20326 - - 0.000000000000001096 87.0
TH2_k127_6204510_9 - - - - 0.00000000009948 65.0
TH2_k127_6287197_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 322.0
TH2_k127_6287197_1 Belongs to the peptidase S11 family K01286,K07258,K07262 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000003316 215.0
TH2_k127_6287197_2 - - - - 0.0000000000000000000000000000000000002372 149.0
TH2_k127_6287197_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000003012 132.0
TH2_k127_6287197_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000001896 143.0
TH2_k127_6307729_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 8.522e-290 900.0
TH2_k127_6307729_1 MCM2/3/5 family K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 340.0
TH2_k127_6307729_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000512 268.0
TH2_k127_6307729_3 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000001083 229.0
TH2_k127_6307729_4 Family membership K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000013 231.0
TH2_k127_6307729_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000009792 214.0
TH2_k127_6307729_6 - - - - 0.00000000000000000000005113 113.0
TH2_k127_6307729_7 Protein of unknown function DUF58 - - - 0.000000000000009386 86.0
TH2_k127_6307729_8 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.000000128 64.0
TH2_k127_6307729_9 Roadblock/LC7 domain - - - 0.0000005434 60.0
TH2_k127_6309621_0 Cytochrome b subunit of the bc complex K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 428.0
TH2_k127_6309621_1 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 387.0
TH2_k127_6309621_11 Putative adhesin - - - 0.000000003361 68.0
TH2_k127_6309621_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 381.0
TH2_k127_6309621_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 322.0
TH2_k127_6309621_4 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000009734 242.0
TH2_k127_6309621_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000004919 218.0
TH2_k127_6309621_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000001643 181.0
TH2_k127_6309621_7 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.000000000000000000000008698 107.0
TH2_k127_6309621_8 - - - - 0.0000000000001226 79.0
TH2_k127_6330822_0 PHP domain protein - - - 1.553e-208 676.0
TH2_k127_6330822_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 3.426e-197 624.0
TH2_k127_6330822_2 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 450.0
TH2_k127_6330822_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 306.0
TH2_k127_6330822_4 PFAM Cold-shock protein, DNA-binding - - - 0.00000000000000000000000000000000000000000000000000000000003901 218.0
TH2_k127_6330822_5 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000007412 121.0
TH2_k127_6330822_6 Dehydrogenase reductase SDR family member K11168 - - 0.0001189 51.0
TH2_k127_6355239_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 306.0
TH2_k127_6373421_0 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 520.0
TH2_k127_6373421_1 Protein serine threonine phosphatase K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 310.0
TH2_k127_6373421_2 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009505 296.0
TH2_k127_6373421_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000005607 157.0
TH2_k127_6373945_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1277.0
TH2_k127_6373945_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002037 250.0
TH2_k127_6373945_3 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000005715 202.0
TH2_k127_6373945_4 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000001017 148.0
TH2_k127_6390926_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000008422 103.0
TH2_k127_6399099_0 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 9e-209 663.0
TH2_k127_6399099_1 Response regulator, receiver K11384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 300.0
TH2_k127_6399099_2 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000116 204.0
TH2_k127_6399099_3 Belongs to the sterol desaturase family K00227 GO:0000139,GO:0000248,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005789,GO:0005794,GO:0006066,GO:0006629,GO:0006694,GO:0006696,GO:0008150,GO:0008152,GO:0008202,GO:0008204,GO:0008610,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016125,GO:0016126,GO:0016128,GO:0016129,GO:0016491,GO:0016705,GO:0016717,GO:0030176,GO:0031090,GO:0031224,GO:0031227,GO:0031974,GO:0031984,GO:0042175,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044107,GO:0044108,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0055114,GO:0070013,GO:0070704,GO:0071704,GO:0097384,GO:0098588,GO:0098791,GO:0098827,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653 1.14.19.20 0.0000000000000000000000000000000000000000009126 167.0
TH2_k127_6410793_0 Belongs to the bacterial histone-like protein family K05788 - - 0.00000000000000000000000000000000000002702 146.0
TH2_k127_6410858_0 DEAD DEAH box helicase - - - 2.978e-300 951.0
TH2_k127_6410858_1 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000001453 162.0
TH2_k127_6410858_2 - - - - 0.000000000000000000000000000008376 131.0
TH2_k127_6410858_3 Outer membrane efflux protein - - - 0.00000000000000000000000002736 123.0
TH2_k127_6410947_0 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 0.0 1161.0
TH2_k127_6410947_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 8.919e-255 807.0
TH2_k127_6410947_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 498.0
TH2_k127_6410947_3 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.0000000000000000000000000000000000000000000002464 173.0
TH2_k127_6410947_4 Biogenesis protein K09792 - - 0.000000000000000000000000000000000003681 146.0
TH2_k127_6410947_5 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000001146 69.0
TH2_k127_6428403_0 Phosphoenolpyruvate phosphomutase K01841 - 5.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 484.0
TH2_k127_6428403_1 PFAM aminotransferase class V K01740,K03430,K05306 GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 401.0
TH2_k127_6428403_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 365.0
TH2_k127_6428403_3 Phytanoyl-CoA dioxygenase (PhyH) K21195 - 1.14.11.46 0.00000000000000000000000000000000000002384 149.0
TH2_k127_6428403_4 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000007489 161.0
TH2_k127_6428403_5 It is involved in the biological process described with cell differentiation K08239 GO:0000139,GO:0001501,GO:0002062,GO:0002063,GO:0002790,GO:0003674,GO:0003824,GO:0003976,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005975,GO:0006491,GO:0006605,GO:0006622,GO:0006623,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007033,GO:0007034,GO:0007040,GO:0007041,GO:0007275,GO:0008104,GO:0008150,GO:0008152,GO:0009100,GO:0009306,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009987,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016256,GO:0016310,GO:0016740,GO:0016772,GO:0016780,GO:0019538,GO:0030154,GO:0031090,GO:0031984,GO:0032501,GO:0032502,GO:0032940,GO:0033036,GO:0033299,GO:0033365,GO:0034613,GO:0042886,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046835,GO:0046903,GO:0046907,GO:0048468,GO:0048513,GO:0048562,GO:0048568,GO:0048598,GO:0048701,GO:0048703,GO:0048704,GO:0048705,GO:0048706,GO:0048731,GO:0048856,GO:0048869,GO:0051179,GO:0051216,GO:0051234,GO:0051641,GO:0051649,GO:0060348,GO:0061448,GO:0061462,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072665,GO:0072666,GO:0080171,GO:0098588,GO:0098791,GO:1901135,GO:1901564,GO:1904888 2.7.8.17 0.0000000000000004558 90.0
TH2_k127_6442346_0 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 447.0
TH2_k127_6442346_1 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02017,K02045,K15497 - 3.6.3.25,3.6.3.29,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 388.0
TH2_k127_6442346_2 sulfate transport system, permease K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 354.0
TH2_k127_6442346_3 Binding-protein-dependent transport system inner membrane component K02046,K15496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 347.0
TH2_k127_6442346_4 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008489 274.0
TH2_k127_6495920_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 7.31e-284 912.0
TH2_k127_6495920_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000005357 257.0
TH2_k127_6495920_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000001795 237.0
TH2_k127_6495920_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000006098 196.0
TH2_k127_6495920_4 Outer membrane efflux protein K15725 - - 0.0000000000000000000000004047 120.0
TH2_k127_6495920_5 Sulfatase-modifying factor enzyme 1 - - - 0.00002084 57.0
TH2_k127_6495920_6 Galactose oxidase, central domain - - - 0.0001451 55.0
TH2_k127_6524_0 Sodium/hydrogen exchanger family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 569.0
TH2_k127_6524_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000009848 221.0
TH2_k127_6524_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000009659 200.0
TH2_k127_6524_3 - - - - 0.0000000000000000000000000000000000000000000000001809 186.0
TH2_k127_6524_4 Cobalamin synthesis protein cobW C-terminal domain - - - 0.0000000000000000000000000001734 129.0
TH2_k127_6524_5 Belongs to the peptidase S1B family - - - 0.00000000000000000000001316 114.0
TH2_k127_6524_6 cheY-homologous receiver domain - - - 0.000000000000000000000094 104.0
TH2_k127_6524_7 - - - - 0.000002671 61.0
TH2_k127_6524_8 FHA domain containing protein - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00003224 57.0
TH2_k127_6524_9 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0007563 48.0
TH2_k127_6555980_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 535.0
TH2_k127_6555980_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 371.0
TH2_k127_6555980_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 306.0
TH2_k127_6555980_3 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000004091 268.0
TH2_k127_6555980_4 - - - - 0.000000000000000000000000000000000000000000000000000000000001198 231.0
TH2_k127_6555980_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000005986 194.0
TH2_k127_6555980_6 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000001829 147.0
TH2_k127_6555980_7 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000004266 99.0
TH2_k127_6555980_8 TPR repeat - - - 0.00000000002117 73.0
TH2_k127_6555980_9 oxidoreductase activity - - - 0.000000007433 68.0
TH2_k127_660024_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 7.821e-252 810.0
TH2_k127_660024_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 3.032e-219 696.0
TH2_k127_660024_10 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004326 284.0
TH2_k127_660024_11 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001432 287.0
TH2_k127_660024_12 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002033 282.0
TH2_k127_660024_13 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003454 276.0
TH2_k127_660024_14 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001037 254.0
TH2_k127_660024_15 transferase activity, transferring glycosyl groups K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000133 262.0
TH2_k127_660024_16 Belongs to the beta-ketoacyl-ACP synthases family K05551,K09458 - 2.3.1.179,2.3.1.235,2.3.1.260 0.000000000000000000000000000000000000000000000000000000000000611 241.0
TH2_k127_660024_17 Glycosyltransferase family 28 N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000003924 223.0
TH2_k127_660024_18 von Willebrand factor type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000001375 221.0
TH2_k127_660024_19 Bacterial SH3 domain homologues - - - 0.00000000000000000000000000000000000000000000000000000006322 209.0
TH2_k127_660024_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 584.0
TH2_k127_660024_20 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000006733 200.0
TH2_k127_660024_21 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000005361 200.0
TH2_k127_660024_22 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000005429 192.0
TH2_k127_660024_23 OHCU decarboxylase K16840 - 4.1.1.97 0.000000000000000000000000000000000000000000006958 171.0
TH2_k127_660024_24 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000001626 161.0
TH2_k127_660024_25 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000006358 164.0
TH2_k127_660024_26 Von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000122 160.0
TH2_k127_660024_27 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000001152 158.0
TH2_k127_660024_28 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000662 134.0
TH2_k127_660024_29 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000003204 126.0
TH2_k127_660024_3 Amidohydrolase family K01466 - 3.5.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 557.0
TH2_k127_660024_30 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000646 104.0
TH2_k127_660024_31 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000004761 107.0
TH2_k127_660024_32 PhnA domain K06193 - - 0.000000000000000000000103 105.0
TH2_k127_660024_33 Domain of unknown function (DUF1844) - - - 0.0000000000000000000004984 101.0
TH2_k127_660024_34 negative regulation of translational initiation - - - 0.000000000000000001111 98.0
TH2_k127_660024_35 Methyltransferase domain - - - 0.00000000000000001174 95.0
TH2_k127_660024_36 - - - - 0.000000000000000298 91.0
TH2_k127_660024_38 START domain - - - 0.0000000000001701 79.0
TH2_k127_660024_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 475.0
TH2_k127_660024_40 Beta-ketoacyl synthase, N-terminal domain K09458 - 2.3.1.179 0.00000000001408 76.0
TH2_k127_660024_41 COG1073 hydrolases of the alpha beta superfamily - - - 0.0000000001414 75.0
TH2_k127_660024_43 Glycosyl transferase family 2 - - - 0.0000000006467 71.0
TH2_k127_660024_5 Belongs to the allantoicase family K01477 - 3.5.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 436.0
TH2_k127_660024_6 Glycosyl hydrolases family 38 N-terminal domain K01191,K15524 - 3.2.1.170,3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 436.0
TH2_k127_660024_7 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 335.0
TH2_k127_660024_8 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 326.0
TH2_k127_660024_9 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001086 297.0
TH2_k127_6604168_0 AcrB/AcrD/AcrF family - - - 0.0 1244.0
TH2_k127_6604168_1 Flavin-binding monooxygenase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 578.0
TH2_k127_6604168_10 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000001444 63.0
TH2_k127_6604168_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 342.0
TH2_k127_6604168_3 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 291.0
TH2_k127_6604168_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002819 286.0
TH2_k127_6604168_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000022 272.0
TH2_k127_6604168_6 xyloglucan:xyloglucosyl transferase activity K01216 - 3.2.1.73 0.00000000000000000000000000000000000001558 165.0
TH2_k127_6604168_7 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000008844 157.0
TH2_k127_6604168_9 Histidine kinase - - - 0.00000000000000003355 94.0
TH2_k127_662358_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1242.0
TH2_k127_662358_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003407 296.0
TH2_k127_662358_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000005992 115.0
TH2_k127_662358_3 DUF218 domain - - - 0.000000000000000000000002477 113.0
TH2_k127_662358_4 - - - - 0.000000000000000001912 91.0
TH2_k127_662358_5 PFAM TPR repeat-containing protein - - - 0.0002886 50.0
TH2_k127_6687731_0 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 321.0
TH2_k127_6687731_1 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004641 252.0
TH2_k127_6687731_2 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001101 240.0
TH2_k127_6687731_3 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000004948 168.0
TH2_k127_6687731_4 - - - - 0.0000000000000001258 84.0
TH2_k127_6693384_0 Sigma-54 interaction domain K10941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 387.0
TH2_k127_6693384_1 Ion transport protein K10716 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.000006327 51.0
TH2_k127_6700247_0 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 440.0
TH2_k127_6700247_1 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 314.0
TH2_k127_6700247_2 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000009216 207.0
TH2_k127_6700247_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000001815 210.0
TH2_k127_6700247_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000506 149.0
TH2_k127_671238_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000003358 227.0
TH2_k127_671238_1 Diacylglycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000000002851 189.0
TH2_k127_6754188_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 473.0
TH2_k127_6754188_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 467.0
TH2_k127_6754188_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000002974 230.0
TH2_k127_6754188_3 - - - - 0.000000000000000000000000000000000000000000000002147 196.0
TH2_k127_6754188_4 methyltransferase - - - 0.00000000000000000000006444 108.0
TH2_k127_6754188_5 Predicted membrane protein (DUF2142) - - - 0.000006379 58.0
TH2_k127_679048_0 Alpha-amylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 582.0
TH2_k127_679048_1 Sugar ABC transporter permease K10109,K15770,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 588.0
TH2_k127_679048_2 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 480.0
TH2_k127_679048_3 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 479.0
TH2_k127_679048_4 TOBE domain K10111 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 350.0
TH2_k127_679048_5 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 333.0
TH2_k127_679048_7 PFAM binding-protein-dependent transport systems inner membrane component K15772 - - 0.0000000000000000000000000000000000000000000000000001053 207.0
TH2_k127_679048_8 PFAM PEGA domain - - - 0.0009318 47.0
TH2_k127_6804778_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 320.0
TH2_k127_6804778_1 Histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002447 275.0
TH2_k127_6804778_2 domain, Protein - - - 0.00000000000000000000000000000000005297 154.0
TH2_k127_6804778_3 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000004117 142.0
TH2_k127_6804778_4 Forkhead associated domain - - - 0.0000000000000000001033 98.0
TH2_k127_6813543_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 1.868e-282 898.0
TH2_k127_6813543_1 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 614.0
TH2_k127_6813543_10 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000003314 243.0
TH2_k127_6813543_11 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000001717 225.0
TH2_k127_6813543_12 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000003955 224.0
TH2_k127_6813543_13 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.0000000000000000001032 91.0
TH2_k127_6813543_14 DnaJ molecular chaperone homology domain - - - 0.000000000000000001185 101.0
TH2_k127_6813543_15 energy transducer activity K02487,K03832,K06596 - - 0.0000000000000002898 91.0
TH2_k127_6813543_17 - - - - 0.000000000001037 80.0
TH2_k127_6813543_18 Transglutaminase-like superfamily - - - 0.0000186 52.0
TH2_k127_6813543_19 - - - - 0.00002338 57.0
TH2_k127_6813543_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 564.0
TH2_k127_6813543_20 peptidyl-tyrosine sulfation - - - 0.00006586 55.0
TH2_k127_6813543_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 526.0
TH2_k127_6813543_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 518.0
TH2_k127_6813543_5 TIGRFAM acetylornithine and succinylornithine aminotransferase K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 383.0
TH2_k127_6813543_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 357.0
TH2_k127_6813543_7 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 357.0
TH2_k127_6813543_8 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009348 273.0
TH2_k127_6813543_9 PFAM PHP domain protein K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000006678 246.0
TH2_k127_685172_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 6.332e-263 835.0
TH2_k127_685172_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 493.0
TH2_k127_685172_10 DNA methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001618 243.0
TH2_k127_685172_11 2OG-Fe(II) oxygenase superfamily K07394 - - 0.00000000000000000000000000000000000000000000000000000000000000000001357 241.0
TH2_k127_685172_12 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000003505 211.0
TH2_k127_685172_13 protein kinase activity - - - 0.00000000000000000000000000000000000001395 166.0
TH2_k127_685172_15 HEAT repeats - - - 0.000000000000000000000000000000005161 149.0
TH2_k127_685172_16 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000002467 96.0
TH2_k127_685172_17 - - - - 0.00000121 59.0
TH2_k127_685172_18 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000002194 60.0
TH2_k127_685172_2 ABC transporter K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006015 477.0
TH2_k127_685172_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 450.0
TH2_k127_685172_4 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 441.0
TH2_k127_685172_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 418.0
TH2_k127_685172_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 303.0
TH2_k127_685172_7 tRNA synthetases class II (D, K and N) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 302.0
TH2_k127_685172_8 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000001058 281.0
TH2_k127_685172_9 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001254 265.0
TH2_k127_6861679_0 Belongs to the ClpA ClpB family K03694 - - 1.33e-299 942.0
TH2_k127_6861679_1 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 437.0
TH2_k127_6861679_2 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 371.0
TH2_k127_6861679_3 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005808 292.0
TH2_k127_6861679_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000001015 121.0
TH2_k127_6861679_5 - - - - 0.000000000000000000001651 104.0
TH2_k127_6861679_6 MAPEG family - - - 0.00000000001673 77.0
TH2_k127_6861679_7 Ankyrin repeat domain 17 K16726 GO:0000785,GO:0001568,GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0001817,GO:0001819,GO:0001944,GO:0001955,GO:0002376,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002831,GO:0002833,GO:0003674,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0006275,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007346,GO:0007399,GO:0007423,GO:0007492,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010506,GO:0010507,GO:0010556,GO:0010564,GO:0010639,GO:0010646,GO:0010647,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0012505,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0021700,GO:0022008,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031329,GO:0031330,GO:0031347,GO:0031349,GO:0031430,GO:0031672,GO:0031674,GO:0031965,GO:0031967,GO:0031975,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0039531,GO:0039533,GO:0039535,GO:0040011,GO:0042692,GO:0042742,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043122,GO:0043123,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043900,GO:0043902,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045214,GO:0045595,GO:0045596,GO:0045787,GO:0045931,GO:0046530,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050688,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051147,GO:0051148,GO:0051150,GO:0051151,GO:0051171,GO:0051239,GO:0051240,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0055001,GO:0055002,GO:0060255,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071695,GO:0071840,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090068,GO:0090596,GO:0097435,GO:0098542,GO:0099080,GO:0099081,GO:0099512,GO:1900087,GO:1900245,GO:1900246,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902531,GO:1902533,GO:1902806,GO:1902808,GO:1903146,GO:1903147,GO:2000045,GO:2000112 - 0.0000000001281 73.0
TH2_k127_6861679_8 - - - - 0.000000003678 69.0
TH2_k127_6918410_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002154 267.0
TH2_k127_6918410_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000005833 113.0
TH2_k127_6918410_3 Domain of unknown function (DUF4157) - - - 0.00000000000000004946 97.0
TH2_k127_6949375_0 Peptidase C39 family K06147 - - 6.432e-256 818.0
TH2_k127_6949375_1 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009545 282.0
TH2_k127_6949375_2 ABC transporter, ATP-binding protein - - - 0.0005617 48.0
TH2_k127_6954_0 - - - - 0.0000000000000000000000000000000000000000009772 180.0
TH2_k127_6968444_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 469.0
TH2_k127_6968444_1 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 436.0
TH2_k127_6968444_2 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000004882 242.0
TH2_k127_6968444_3 Cellulase (glycosyl hydrolase family 5) - - - 0.00000000000000000000000000000000000000000000000000000001929 217.0
TH2_k127_6968444_4 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000005203 186.0
TH2_k127_6968444_5 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000006594 166.0
TH2_k127_6968444_6 Outer membrane efflux protein - - - 0.00000000000000000000000000001872 134.0
TH2_k127_6968444_7 MlaC protein K07323 - - 0.00000000000000000000000007374 117.0
TH2_k127_6978351_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 576.0
TH2_k127_6978351_1 RecQ zinc-binding K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 453.0
TH2_k127_6978351_2 PAS domain - - - 0.0000000000000000000000000000000000000000000001148 182.0
TH2_k127_6978351_3 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000001718 132.0
TH2_k127_6978351_4 COG0517, FOG CBS domain - - - 0.0000000000000000000000411 115.0
TH2_k127_6978351_5 cheY-homologous receiver domain - - - 0.00000000000000000008104 104.0
TH2_k127_6978351_7 diguanylate cyclase - - - 0.000000000303 73.0
TH2_k127_6978351_8 transcriptional - - - 0.00002387 48.0
TH2_k127_6985032_0 4Fe-4S dicluster domain K00184 - - 6.8e-275 882.0
TH2_k127_6985032_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 9.381e-257 803.0
TH2_k127_6985032_10 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003475 263.0
TH2_k127_6985032_11 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000006926 261.0
TH2_k127_6985032_12 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000002746 242.0
TH2_k127_6985032_13 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000001224 209.0
TH2_k127_6985032_14 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000026 217.0
TH2_k127_6985032_16 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000001957 160.0
TH2_k127_6985032_18 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000003245 145.0
TH2_k127_6985032_19 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.0000000000000004062 82.0
TH2_k127_6985032_2 4Fe-4S binding domain - - - 5.186e-219 702.0
TH2_k127_6985032_20 von Willebrand factor (vWF) type A domain - - - 0.000000000000002734 87.0
TH2_k127_6985032_21 protein conserved in bacteria - - - 0.00000001525 60.0
TH2_k127_6985032_3 Polysulphide reductase, NrfD K00185 - - 1.12e-202 640.0
TH2_k127_6985032_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 587.0
TH2_k127_6985032_5 GAF domain K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 548.0
TH2_k127_6985032_6 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 413.0
TH2_k127_6985032_7 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 373.0
TH2_k127_6985032_8 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 289.0
TH2_k127_702310_0 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 616.0
TH2_k127_702310_1 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 558.0
TH2_k127_702310_10 alpha beta - - - 0.000000000000000000000000000000000000007187 168.0
TH2_k127_702310_11 SNARE associated Golgi protein - - - 0.000000000000000000000002556 110.0
TH2_k127_702310_13 Putative metal-binding motif - - - 0.00001677 57.0
TH2_k127_702310_14 Periplasmic copper-binding protein (NosD) - - - 0.0009894 52.0
TH2_k127_702310_2 COG3666 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 527.0
TH2_k127_702310_3 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 413.0
TH2_k127_702310_4 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 327.0
TH2_k127_702310_5 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 293.0
TH2_k127_702310_6 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000141 216.0
TH2_k127_702310_7 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000001116 199.0
TH2_k127_702310_8 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000000008995 203.0
TH2_k127_702310_9 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000001841 179.0
TH2_k127_7025849_0 FtsX-like permease family K02004 - - 7.998e-205 664.0
TH2_k127_7025849_1 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 482.0
TH2_k127_7025849_10 integral membrane protein - - - 0.0000000000000000000000000000000000000001209 162.0
TH2_k127_7025849_11 DNA-binding transcription factor activity K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000005818 129.0
TH2_k127_7025849_12 Kelch motif - - - 0.000000000000000000000000000008737 138.0
TH2_k127_7025849_13 isoform X1 - - - 0.0000000000000005804 89.0
TH2_k127_7025849_2 Ergosterol biosynthesis ERG4/ERG24 family K00213 - 1.3.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 441.0
TH2_k127_7025849_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 430.0
TH2_k127_7025849_4 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 406.0
TH2_k127_7025849_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 376.0
TH2_k127_7025849_6 (ABC) transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 342.0
TH2_k127_7025849_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000001873 229.0
TH2_k127_7025849_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000005092 215.0
TH2_k127_7025849_9 protein involved in exopolysaccharide biosynthesis K16554 - - 0.00000000000000000000000000000000000000000000000007911 201.0
TH2_k127_7055638_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 1.569e-245 827.0
TH2_k127_7055638_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 452.0
TH2_k127_7055638_2 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001663 274.0
TH2_k127_7055638_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000001136 207.0
TH2_k127_7055638_4 BON domain - - - 0.000000000000000000000000000000000000000000000001152 181.0
TH2_k127_7055638_5 PFAM Host attachment protein - - - 0.00000000000000000006682 102.0
TH2_k127_7055638_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00002937 50.0
TH2_k127_706964_0 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 478.0
TH2_k127_706964_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 420.0
TH2_k127_706964_10 Ribosomal protein S9/S16 K02996 - - 0.00000000000000000000000000000000000000000000003084 178.0
TH2_k127_706964_11 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000007299 190.0
TH2_k127_706964_12 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000007127 169.0
TH2_k127_706964_13 - - - - 0.000000000000000000000000000000000000003318 164.0
TH2_k127_706964_14 GGDEF domain - - - 0.00000000000000000000000006012 120.0
TH2_k127_706964_15 PFAM Peptidase M23 - - - 0.000000000000000000805 100.0
TH2_k127_706964_16 regulation of response to stimulus K02014,K13730 - - 0.000000000000009102 88.0
TH2_k127_706964_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 370.0
TH2_k127_706964_3 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 339.0
TH2_k127_706964_4 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 323.0
TH2_k127_706964_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000003104 248.0
TH2_k127_706964_6 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003459 251.0
TH2_k127_706964_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000002141 242.0
TH2_k127_706964_8 fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000003324 225.0
TH2_k127_706964_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001382 184.0
TH2_k127_7087061_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 4.319e-266 859.0
TH2_k127_7087061_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 3.355e-206 657.0
TH2_k127_7087061_10 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000001366 138.0
TH2_k127_7087061_11 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000009257 99.0
TH2_k127_7087061_12 Catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs K06177 - 5.4.99.28,5.4.99.29 0.0000000000000395 85.0
TH2_k127_7087061_13 Long-chain fatty acid transport protein K06076 - - 0.00000000004609 76.0
TH2_k127_7087061_14 Calcineurin-like phosphoesterase K07098 - - 0.0000003294 63.0
TH2_k127_7087061_15 methyltransferase - - - 0.00008007 55.0
TH2_k127_7087061_2 Flagellar Motor Protein K11892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 547.0
TH2_k127_7087061_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 383.0
TH2_k127_7087061_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000008654 250.0
TH2_k127_7087061_5 Alpha-amylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001487 256.0
TH2_k127_7087061_6 Protein of unknown function (DUF1456) - - - 0.00000000000000000000000000000000000000000000000004667 183.0
TH2_k127_7087061_7 rna methyltransferase K03437 - - 0.00000000000000000000000000000000000000000007103 174.0
TH2_k127_7087061_8 Low affinity iron permease - - - 0.0000000000000000000000000000000000000003286 168.0
TH2_k127_7087061_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000007107 148.0
TH2_k127_7127043_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.841e-294 942.0
TH2_k127_7127043_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 373.0
TH2_k127_7127043_2 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004074 289.0
TH2_k127_7127043_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000005179 256.0
TH2_k127_7127043_4 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000005193 214.0
TH2_k127_7127043_5 Biotin carboxyl carrier protein - - - 0.0000000000000002066 85.0
TH2_k127_7127043_6 membrane - - - 0.000000000001155 78.0
TH2_k127_7127043_7 Protein of unknown function (DUF962) - - - 0.00000000001655 78.0
TH2_k127_7154388_0 DNA polymerase III K02341 - 2.7.7.7 0.000000000000000000000000000000000000001517 164.0
TH2_k127_7154388_1 FHA domain - - - 0.000000000000000000000008208 115.0
TH2_k127_7154388_2 PspA/IM30 family K03969 - - 0.000000000005745 76.0
TH2_k127_7154527_0 Large extracellular alpha-helical protein - - - 0.0 1873.0
TH2_k127_7154527_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 339.0
TH2_k127_7154527_2 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 304.0
TH2_k127_7154527_3 RNA recognition motif - - - 0.000000000000000000000001302 111.0
TH2_k127_7160944_0 protease with the C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 497.0
TH2_k127_7160944_1 nitric oxide dioxygenase activity K00523 - 1.17.1.1 0.000000000000000000000000000005922 129.0
TH2_k127_7160944_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000001745 90.0
TH2_k127_7162885_0 repeat protein - - - 0.0 3338.0
TH2_k127_7162885_1 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00239 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 2.224e-238 763.0
TH2_k127_7162885_2 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 440.0
TH2_k127_7162885_3 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 398.0
TH2_k127_7162885_4 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 342.0
TH2_k127_7162885_5 succinate dehydrogenase K00241 - - 0.00000000000000000000000000000000000000000005063 169.0
TH2_k127_7162885_6 FHA domain - - - 0.000000000000000000000000035 123.0
TH2_k127_7162885_7 TPR repeat-containing protein - - - 0.00000000000000000001211 103.0
TH2_k127_7162885_8 Putative glutamine amidotransferase - - - 0.00000000000002141 79.0
TH2_k127_7162885_9 - - - - 0.000009048 58.0
TH2_k127_7210941_0 phosphoglycolate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000006026 248.0
TH2_k127_7210941_1 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000001083 239.0
TH2_k127_7210941_2 Domain of unknown function (DUF2760) - - - 0.00000000000000000000000000000000000001784 151.0
TH2_k127_7210941_3 MreB/Mbl protein - - - 0.000000000000001565 82.0
TH2_k127_7224646_0 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 330.0
TH2_k127_7224646_1 Transposase domain (DUF772) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001009 274.0
TH2_k127_7224646_10 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000005419 107.0
TH2_k127_7224646_11 PAS fold - - - 0.000000000000000000014 107.0
TH2_k127_7224646_12 Response regulator receiver modulated diguanylate cyclase phosphodiesterase - - - 0.000000000000000004651 94.0
TH2_k127_7224646_13 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000002711 78.0
TH2_k127_7224646_14 Carotene biosynthesis associated membrane protein K14337,K14339 - - 0.0000000005072 72.0
TH2_k127_7224646_16 Two component regulator propeller - - - 0.0000002268 64.0
TH2_k127_7224646_19 Belongs to the UPF0200 family - - - 0.0006075 50.0
TH2_k127_7224646_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008263 261.0
TH2_k127_7224646_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001651 239.0
TH2_k127_7224646_4 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000003628 226.0
TH2_k127_7224646_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000008474 214.0
TH2_k127_7224646_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000006361 195.0
TH2_k127_7224646_7 Domain of unknown function (DUF4175) - - - 0.00000000000000000000000000000000000000000000000000009229 213.0
TH2_k127_7224646_8 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000005428 182.0
TH2_k127_7224646_9 PFAM transposase IS4 family protein - - - 0.000000000000000000000000000000000000000000007397 166.0
TH2_k127_724148_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 0.0 1501.0
TH2_k127_724148_1 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 6.944e-219 685.0
TH2_k127_724148_2 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 551.0
TH2_k127_724148_3 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 494.0
TH2_k127_724148_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 326.0
TH2_k127_724148_5 Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus K07261 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034645,GO:0042221,GO:0042493,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0050896,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 288.0
TH2_k127_724148_6 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000042 250.0
TH2_k127_724148_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000007923 145.0
TH2_k127_724148_8 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K01256,K02563,K02652,K08776,K12132 - 2.4.1.227,2.7.11.1,3.4.11.2 0.000000000000000000000001109 119.0
TH2_k127_724148_9 DbpA RNA binding domain K05592 - 3.6.4.13 0.00000000001665 73.0
TH2_k127_724628_0 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.000000000000000000000001837 119.0
TH2_k127_724628_1 Belongs to the LOG family K06966 - 3.2.2.10 0.00000005472 66.0
TH2_k127_724628_2 Tyrosine phosphatase family - - - 0.0002581 54.0
TH2_k127_7287150_0 Asparagine synthase K01953 - 6.3.5.4 3.35e-285 892.0
TH2_k127_7287150_1 AMP-binding enzyme K01897 - 6.2.1.3 1.447e-236 747.0
TH2_k127_7287150_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000104 283.0
TH2_k127_7287150_3 RNA cap guanine-N2 methyltransferase K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000007856 261.0
TH2_k127_7287150_4 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006173 256.0
TH2_k127_7287150_5 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000000000000000002075 207.0
TH2_k127_7287150_6 - - - - 0.0000000002075 70.0
TH2_k127_7287150_7 Predicted integral membrane protein (DUF2269) - - - 0.00002978 52.0
TH2_k127_7288375_0 Transposase - - - 0.00000000000000000000005397 101.0
TH2_k127_7288375_1 Phage integrase family - - - 0.00000000000000008143 91.0
TH2_k127_7288375_2 histone H2A K63-linked ubiquitination - - - 0.00000000005333 73.0
TH2_k127_7436265_0 OPT oligopeptide transporter protein - - - 8.888e-289 896.0
TH2_k127_7436265_1 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 2.4e-275 861.0
TH2_k127_7436265_10 SMART serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000002169 257.0
TH2_k127_7436265_11 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000001836 250.0
TH2_k127_7436265_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000007145 196.0
TH2_k127_7436265_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000002659 178.0
TH2_k127_7436265_14 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000001249 179.0
TH2_k127_7436265_15 - - - - 0.000000000000000000000000000000000000000000008057 174.0
TH2_k127_7436265_16 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000005837 135.0
TH2_k127_7436265_17 Protein of unknown function (DUF3467) - - - 0.000000000000000000000000002585 114.0
TH2_k127_7436265_18 - - - - 0.00000000000000000000000003953 120.0
TH2_k127_7436265_19 Putative Phosphatase K08966 - 3.1.3.87 0.000000000000000000000003844 110.0
TH2_k127_7436265_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 2.413e-227 721.0
TH2_k127_7436265_20 Belongs to the UPF0758 family K03630 - - 0.00000000000000000005593 102.0
TH2_k127_7436265_23 AntiSigma factor K03088 - - 0.000008213 55.0
TH2_k127_7436265_3 PFAM Aminotransferase class I and II K14287 - 2.6.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 580.0
TH2_k127_7436265_4 synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 561.0
TH2_k127_7436265_5 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 518.0
TH2_k127_7436265_6 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 388.0
TH2_k127_7436265_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 333.0
TH2_k127_7436265_8 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 349.0
TH2_k127_7436265_9 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 316.0
TH2_k127_7440136_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 467.0
TH2_k127_7441858_0 UPF0210 protein K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 604.0
TH2_k127_7441858_1 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005983 286.0
TH2_k127_7441858_10 Domain of unknown function (DUF4437) - - - 0.000000000003411 74.0
TH2_k127_7441858_12 Belongs to the UPF0237 family K07166 - - 0.0000000007374 69.0
TH2_k127_7441858_13 Ethanolamine utilization protein EutN K04028 - - 0.00000003208 59.0
TH2_k127_7441858_14 Cysteine-rich secretory protein family - - - 0.0000001368 63.0
TH2_k127_7441858_15 COG4576 Carbon dioxide concentrating mechanism carboxysome shell protein K04028 - - 0.0000004717 58.0
TH2_k127_7441858_17 DNA RNA non-specific endonuclease - - - 0.0002197 54.0
TH2_k127_7441858_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002143 273.0
TH2_k127_7441858_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000004876 187.0
TH2_k127_7441858_4 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000009136 149.0
TH2_k127_7441858_5 EamA-like transporter family - - - 0.00000000000000000000000002753 127.0
TH2_k127_7441858_6 - - - - 0.0000000000000000000002561 100.0
TH2_k127_7441858_7 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000005191 76.0
TH2_k127_7441858_8 Ethanolamine utilization protein EutN K04028 - - 0.0000000000005985 74.0
TH2_k127_7441858_9 - - - - 0.000000000001047 78.0
TH2_k127_7460920_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.146e-310 975.0
TH2_k127_7460920_1 5' nucleotidase family - - - 4.173e-205 648.0
TH2_k127_7460920_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 547.0
TH2_k127_7460920_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 455.0
TH2_k127_7460920_4 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.5.2,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 376.0
TH2_k127_7460920_5 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 334.0
TH2_k127_7460920_6 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001188 257.0
TH2_k127_7460920_7 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000001322 246.0
TH2_k127_7460920_8 - - - - 0.00000000000000000000000000000000156 140.0
TH2_k127_7460920_9 OmpA family K03640 - - 0.000000000000000000000008063 111.0
TH2_k127_7498773_0 belongs to the aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 506.0
TH2_k127_7498773_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 507.0
TH2_k127_7498773_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 331.0
TH2_k127_7498773_3 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006125 289.0
TH2_k127_7498773_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000033 224.0
TH2_k127_7498773_5 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000009606 219.0
TH2_k127_7498773_6 Belongs to the sigma-70 factor family K02405 - - 0.000000000000000000000000000000000000000000000000392 194.0
TH2_k127_7498773_7 PFAM Photosynthetic reaction centre cytochrome C subunit K13992 - - 0.000000000000000004985 88.0
TH2_k127_7498773_8 COG4669 Type III secretory pathway, lipoprotein EscJ K03222 - - 0.0000000000000000279 91.0
TH2_k127_7498773_9 sh3 domain protein - - - 0.000000000000000886 85.0
TH2_k127_7541224_0 CoA-transferase family III K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000984 345.0
TH2_k127_7541224_1 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001151 299.0
TH2_k127_7541224_2 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000001646 138.0
TH2_k127_7541224_3 glutamate-tRNA ligase activity K01885,K09698 - 6.1.1.17,6.1.1.24 0.00000000000000000000000000000000003568 139.0
TH2_k127_7541224_4 domain, Protein - - - 0.00000000000000000000021 107.0
TH2_k127_7541224_5 Glycoprotease family K14742 - - 0.00000000000000000005745 99.0
TH2_k127_7546880_0 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 468.0
TH2_k127_7546880_1 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 491.0
TH2_k127_7546880_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 387.0
TH2_k127_7546880_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 362.0
TH2_k127_7546880_4 Belongs to the glycosyl hydrolase 32 family K01193 - 3.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000003891 264.0
TH2_k127_7546880_5 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000001035 225.0
TH2_k127_7546880_6 GtrA-like protein K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000001823 191.0
TH2_k127_7546880_7 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000002855 179.0
TH2_k127_756046_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 595.0
TH2_k127_756046_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000287 219.0
TH2_k127_756046_2 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000005485 196.0
TH2_k127_756046_3 TraB family K09973 - - 0.0000005755 58.0
TH2_k127_7567572_0 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003651 290.0
TH2_k127_7567572_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000003825 253.0
TH2_k127_7567572_2 PFAM tRNAHis guanylyltransferase - - - 0.000000000000000000000000000000007735 140.0
TH2_k127_7596384_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.372e-239 771.0
TH2_k127_7596384_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 459.0
TH2_k127_7596384_10 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000002264 217.0
TH2_k127_7596384_11 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000001879 173.0
TH2_k127_7596384_12 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000002165 160.0
TH2_k127_7596384_13 - - - - 0.000000000000000000000000000000000005197 145.0
TH2_k127_7596384_14 - - - - 0.0000000000000000000000000000007261 141.0
TH2_k127_7596384_15 heme binding K21472 - - 0.00000000000000000000000005369 119.0
TH2_k127_7596384_16 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000001148 122.0
TH2_k127_7596384_17 TPR repeat - - - 0.0000000000001364 81.0
TH2_k127_7596384_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 405.0
TH2_k127_7596384_3 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 356.0
TH2_k127_7596384_4 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 342.0
TH2_k127_7596384_5 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 304.0
TH2_k127_7596384_6 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000276 283.0
TH2_k127_7596384_7 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000109 276.0
TH2_k127_7596384_8 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007211 243.0
TH2_k127_7596384_9 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000537 245.0
TH2_k127_7607762_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000282 297.0
TH2_k127_7607762_1 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003168 239.0
TH2_k127_7607762_2 light absorption - - - 0.00000000000000000003198 100.0
TH2_k127_7607762_3 Protein of unknown function (DUF1328) - - - 0.00000000002845 74.0
TH2_k127_7627294_0 Domain of unknown function (DUF4395) - - - 0.000000000000000000000000000000000002208 143.0
TH2_k127_7627294_1 Protein of unknown function, DUF393 - - - 0.00000000000000000000000000004242 128.0
TH2_k127_7627294_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000004068 81.0
TH2_k127_764907_0 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 4.035e-212 683.0
TH2_k127_764907_1 SNF2 family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 437.0
TH2_k127_764907_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 347.0
TH2_k127_764907_3 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000002676 223.0
TH2_k127_7727190_0 SMART helicase c2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 496.0
TH2_k127_7727190_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000004967 149.0
TH2_k127_7727190_2 - - - - 0.0000000000000000005975 100.0
TH2_k127_7732698_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 566.0
TH2_k127_7732698_1 PFAM acyltransferase 3 - - - 0.000000000000000000000000001948 118.0
TH2_k127_7732698_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000001474 103.0
TH2_k127_7732698_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0005841 49.0
TH2_k127_7733655_0 AcrB/AcrD/AcrF family K03296 - - 1.086e-281 898.0
TH2_k127_7733655_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004571 288.0
TH2_k127_7733655_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000021 178.0
TH2_k127_7733655_3 Acyltransferase family - - - 0.000000000000000000000000000000000004425 147.0
TH2_k127_7733655_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000008199 112.0
TH2_k127_7733655_5 - - - - 0.0000000000001669 81.0
TH2_k127_7733655_6 - - - - 0.00000002359 65.0
TH2_k127_774859_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 9.325e-238 773.0
TH2_k127_774859_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008373 492.0
TH2_k127_774859_10 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000004894 103.0
TH2_k127_774859_11 - - - - 0.00000000000002243 83.0
TH2_k127_774859_12 Gamma-glutamyltranspeptidase - - - 0.000000000009089 76.0
TH2_k127_774859_13 - - - - 0.0000000002351 73.0
TH2_k127_774859_14 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000776 55.0
TH2_k127_774859_2 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 402.0
TH2_k127_774859_3 YARHG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 376.0
TH2_k127_774859_4 Membrane dipeptidase (Peptidase family M19) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 385.0
TH2_k127_774859_5 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 338.0
TH2_k127_774859_6 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 312.0
TH2_k127_774859_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 312.0
TH2_k127_774859_8 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002708 282.0
TH2_k127_774859_9 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000000000000000000000664 223.0
TH2_k127_775458_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 602.0
TH2_k127_775458_1 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 442.0
TH2_k127_775458_2 Rhodanese-related sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000005532 177.0
TH2_k127_775458_3 YHS domain K06966 - 3.2.2.10 0.000000000000000000000000000000000000006955 152.0
TH2_k127_775458_4 Thioesterase-like superfamily K01073 - 3.1.2.20 0.0000000000000000000009851 102.0
TH2_k127_775458_5 COG0607 Rhodanese-related sulfurtransferase K03972 - - 0.000000000005376 79.0
TH2_k127_775458_6 ATPase involved in DNA repair - - - 0.0009736 50.0
TH2_k127_7818152_0 response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 596.0
TH2_k127_7818152_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 609.0
TH2_k127_7818152_10 Bacterial membrane protein, YfhO - - - 0.00001112 59.0
TH2_k127_7818152_2 Aldehyde dehydrogenase family K04021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 561.0
TH2_k127_7818152_3 BMC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 310.0
TH2_k127_7818152_4 TIGRFAM channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002812 249.0
TH2_k127_7818152_5 BMC K04027 - - 0.000000000000000000000000000000000000000000005589 164.0
TH2_k127_7818152_6 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000000000000000002473 141.0
TH2_k127_7818152_7 propanediol utilization protein - - - 0.000000000000000000000000000002638 128.0
TH2_k127_7818152_8 Adenylate cyclase K01768 - 4.6.1.1 0.000000000002174 74.0
TH2_k127_7818152_9 General secretion pathway protein C K02452 - - 0.00000002053 63.0
TH2_k127_7843904_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 457.0
TH2_k127_7843904_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 357.0
TH2_k127_7843904_10 Phage integrase family K07497 - - 0.0000001184 60.0
TH2_k127_7843904_11 amine dehydrogenase activity - - - 0.0000001273 63.0
TH2_k127_7843904_12 START domain - - - 0.000007424 58.0
TH2_k127_7843904_2 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 325.0
TH2_k127_7843904_3 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009031 307.0
TH2_k127_7843904_4 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001545 246.0
TH2_k127_7843904_5 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000002126 173.0
TH2_k127_7843904_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000007838 107.0
TH2_k127_7843904_7 transcriptional regulator - - - 0.000000001351 61.0
TH2_k127_7843904_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000004258 59.0
TH2_k127_7843904_9 - - - - 0.00000003614 64.0
TH2_k127_7874542_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000002411 138.0
TH2_k127_7876723_0 phosphatase K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004728 274.0
TH2_k127_7876723_1 peptidyl-tyrosine sulfation - - - 0.00000000003752 71.0
TH2_k127_7883814_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 362.0
TH2_k127_7883814_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 347.0
TH2_k127_7883814_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 308.0
TH2_k127_7883814_3 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000362 160.0
TH2_k127_7887582_0 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000001471 167.0
TH2_k127_7887582_1 COG0517, FOG CBS domain - - - 0.0000000000000000000000000000000000003683 150.0
TH2_k127_7887582_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000003566 119.0
TH2_k127_7887582_3 ChaB K06197 - - 0.00000000000000000009646 90.0
TH2_k127_7887582_4 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000002268 67.0
TH2_k127_7891663_0 Heat shock 70 kDa protein K04043,K04045 - - 5.763e-203 647.0
TH2_k127_7891663_1 NADH oxidase - - - 3.107e-194 621.0
TH2_k127_7891663_10 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 322.0
TH2_k127_7891663_11 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 321.0
TH2_k127_7891663_12 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 288.0
TH2_k127_7891663_13 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001234 283.0
TH2_k127_7891663_14 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003547 272.0
TH2_k127_7891663_15 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004101 272.0
TH2_k127_7891663_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004958 264.0
TH2_k127_7891663_17 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000008214 250.0
TH2_k127_7891663_18 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009946 248.0
TH2_k127_7891663_19 heat shock protein binding K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000000146 255.0
TH2_k127_7891663_2 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 548.0
TH2_k127_7891663_20 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001819 231.0
TH2_k127_7891663_21 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000001566 230.0
TH2_k127_7891663_22 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000005915 231.0
TH2_k127_7891663_23 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000005957 211.0
TH2_k127_7891663_24 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000004013 214.0
TH2_k127_7891663_25 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000009224 201.0
TH2_k127_7891663_26 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000009509 211.0
TH2_k127_7891663_27 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000003856 190.0
TH2_k127_7891663_28 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000004693 184.0
TH2_k127_7891663_3 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 505.0
TH2_k127_7891663_30 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000004013 173.0
TH2_k127_7891663_31 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000008357 164.0
TH2_k127_7891663_32 - - - - 0.0000000000000000000000000000000000000006944 169.0
TH2_k127_7891663_33 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000001217 156.0
TH2_k127_7891663_34 Ferredoxin - - - 0.00000000000000000000000000000001358 135.0
TH2_k127_7891663_35 Endoribonuclease L-PSP - - - 0.000000000000000000000000000002254 124.0
TH2_k127_7891663_36 hydroperoxide reductase activity - - - 0.0000000000000000000000000003558 116.0
TH2_k127_7891663_37 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.00000000000000000000000008148 118.0
TH2_k127_7891663_38 hydroperoxide reductase activity - - - 0.000000000000000000000007836 102.0
TH2_k127_7891663_39 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000001521 104.0
TH2_k127_7891663_4 PFAM AMP-dependent synthetase and ligase K04110 - 6.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 446.0
TH2_k127_7891663_40 Uncharacterized protein family UPF0016 - - - 0.0000000000000000002436 90.0
TH2_k127_7891663_41 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000003643 89.0
TH2_k127_7891663_43 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000003568 84.0
TH2_k127_7891663_44 - - - - 0.00000000000001317 88.0
TH2_k127_7891663_45 Lysin motif K08307 - - 0.00000000001179 71.0
TH2_k127_7891663_46 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000001087 71.0
TH2_k127_7891663_47 Ferulic acid esterase (FaeA) - - - 0.00000000014 73.0
TH2_k127_7891663_49 BFD-like [2Fe-2S] binding domain - - - 0.00000002927 60.0
TH2_k127_7891663_5 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 462.0
TH2_k127_7891663_50 Chlorophyllase - - - 0.0000000496 64.0
TH2_k127_7891663_52 YHS domain K06966 - 3.2.2.10 0.0000003572 63.0
TH2_k127_7891663_53 HicB family - - - 0.00001152 56.0
TH2_k127_7891663_55 sequence-specific DNA binding - - - 0.0006856 52.0
TH2_k127_7891663_6 Coproporphyrinogen III oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 402.0
TH2_k127_7891663_7 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 405.0
TH2_k127_7891663_8 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 342.0
TH2_k127_7891663_9 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 325.0
TH2_k127_7922528_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.289e-286 897.0
TH2_k127_7922528_1 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000005392 237.0
TH2_k127_7922528_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000004353 219.0
TH2_k127_7922528_3 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000001005 171.0
TH2_k127_7947432_0 UPF0313 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 346.0
TH2_k127_7947432_1 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000002647 166.0
TH2_k127_7953859_0 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 605.0
TH2_k127_7953859_1 Belongs to the GarS family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 538.0
TH2_k127_7953859_10 succinylglutamate desuccinylase activity K05526 - 3.5.1.96 0.000000000000000000000000000000000000000000000000000000001568 212.0
TH2_k127_7953859_11 DoxX K15977 - - 0.0000000000000000000000000000000000000000000002295 170.0
TH2_k127_7953859_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000002502 54.0
TH2_k127_7953859_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 554.0
TH2_k127_7953859_3 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 462.0
TH2_k127_7953859_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 460.0
TH2_k127_7953859_5 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 447.0
TH2_k127_7953859_6 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 394.0
TH2_k127_7953859_7 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 333.0
TH2_k127_7953859_8 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 289.0
TH2_k127_7953859_9 Belongs to the peptidase S51 family - - - 0.000000000000000000000000000000000000000000000000000000001513 212.0
TH2_k127_7960625_0 Rieske 2Fe-2S domain protein K09879 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 456.0
TH2_k127_7960625_1 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006916 416.0
TH2_k127_7960625_10 - - - - 0.0000000000000000000000000000000001123 134.0
TH2_k127_7960625_11 zinc-ribbon domain - - - 0.00000000000000000000000000005273 135.0
TH2_k127_7960625_12 RNA recognition motif - - - 0.0000000000000000000000000009478 117.0
TH2_k127_7960625_13 Transcription factor zinc-finger K09981 - - 0.00000000000000000000008456 101.0
TH2_k127_7960625_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 389.0
TH2_k127_7960625_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 314.0
TH2_k127_7960625_4 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001468 264.0
TH2_k127_7960625_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000521 271.0
TH2_k127_7960625_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000001595 212.0
TH2_k127_7960625_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000001632 192.0
TH2_k127_7960625_8 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000005893 151.0
TH2_k127_7960625_9 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000002505 145.0
TH2_k127_7962860_0 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 392.0
TH2_k127_7962860_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009786 409.0
TH2_k127_7962860_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001265 297.0
TH2_k127_7962860_11 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001823 283.0
TH2_k127_7962860_12 Small GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001609 274.0
TH2_k127_7962860_13 High-affinity branched-chain amino acid transport protein (ABC superfamily K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002421 274.0
TH2_k127_7962860_14 Branched-chain amino acid transport system / permease component K01997,K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000017 288.0
TH2_k127_7962860_15 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004477 277.0
TH2_k127_7962860_16 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000003807 258.0
TH2_k127_7962860_17 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001076 250.0
TH2_k127_7962860_18 M6 family metalloprotease domain protein - - - 0.0000000000000000000002747 113.0
TH2_k127_7962860_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 372.0
TH2_k127_7962860_3 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 367.0
TH2_k127_7962860_4 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 366.0
TH2_k127_7962860_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 336.0
TH2_k127_7962860_6 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 319.0
TH2_k127_7962860_7 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 296.0
TH2_k127_7962860_8 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 304.0
TH2_k127_7962860_9 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 304.0
TH2_k127_796843_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 491.0
TH2_k127_796843_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008798 453.0
TH2_k127_796843_10 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000001412 241.0
TH2_k127_796843_11 cytochrome complex assembly K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.00000000000000000006133 96.0
TH2_k127_796843_12 Xylose isomerase-like TIM barrel - - - 0.0000002367 62.0
TH2_k127_796843_2 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 425.0
TH2_k127_796843_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 406.0
TH2_k127_796843_4 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 376.0
TH2_k127_796843_5 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 369.0
TH2_k127_796843_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000125 280.0
TH2_k127_796843_7 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003161 278.0
TH2_k127_796843_8 tRNA rRNA methyltransferase (SpoU) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005063 252.0
TH2_k127_796843_9 Bacterial regulatory protein, Fis family K15012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007084 258.0
TH2_k127_7990502_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 361.0
TH2_k127_7990502_1 sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 358.0
TH2_k127_7990502_12 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000001278 61.0
TH2_k127_7990502_13 Flagellar basal body rod K02396 - - 0.0004795 46.0
TH2_k127_7990502_2 Serine Threonine protein kinase K01286,K08884,K12132 - 2.7.11.1,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 325.0
TH2_k127_7990502_3 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000155 289.0
TH2_k127_7990502_4 response regulator K02282,K20971 - - 0.000000000000000000000000000000000000000000000000000000000000000000002063 251.0
TH2_k127_7990502_5 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000009889 192.0
TH2_k127_7990502_6 Yqey-like protein K09117 - - 0.0000000000000000000000000000000002428 139.0
TH2_k127_7990502_7 peptidase activity, acting on L-amino acid peptides K20276 - - 0.0000000000000000002332 102.0
TH2_k127_7990502_8 - - - - 0.0000000000000003854 85.0
TH2_k127_7990502_9 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000009036 71.0
TH2_k127_8013325_0 Type II IV secretion system protein K02283,K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 462.0
TH2_k127_8013325_1 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000003965 232.0
TH2_k127_8013325_2 Response regulator, receiver K02282 - - 0.00000000000000000000000000000000000000000006177 175.0
TH2_k127_8013325_3 Transthyretin K07127 - 3.5.2.17 0.00000000000000000000000000000000000001051 148.0
TH2_k127_8013325_4 type II secretion system K12511 - - 0.00000000000000000001674 104.0
TH2_k127_8013325_5 Type II secretion system (T2SS), protein F K12510 - - 0.0000000000000000000308 104.0
TH2_k127_8013325_6 TPR repeat - - - 0.000000000001661 78.0
TH2_k127_8013325_7 Flp Fap pilin component K02651 - - 0.000000003662 60.0
TH2_k127_8013325_8 von Willebrand factor (vWF) type A domain K07114 - - 0.000002295 60.0
TH2_k127_8039540_0 metal-dependent phosphohydrolase HD - - - 8.362e-198 629.0
TH2_k127_8039540_1 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 448.0
TH2_k127_8039540_10 Redoxin K02199 - - 0.000000000000000007393 96.0
TH2_k127_8039540_2 PFAM MscS Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 327.0
TH2_k127_8039540_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 311.0
TH2_k127_8039540_4 serine-type endopeptidase activity K04771,K08372 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 322.0
TH2_k127_8039540_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000007573 250.0
TH2_k127_8039540_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000155 197.0
TH2_k127_8039540_7 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000002231 162.0
TH2_k127_8039540_8 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002738 150.0
TH2_k127_8039540_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001244 120.0
TH2_k127_8044066_0 RIO1 family K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 375.0
TH2_k127_8044066_1 Sterol desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 361.0
TH2_k127_8044066_2 YaeQ - - - 0.0000000000000000000000000000000000000000000000000000000004433 207.0
TH2_k127_8044066_3 PFAM globin K06886 - - 0.0000000000000000000000000000000000000000002142 163.0
TH2_k127_8044066_4 - - - - 0.00000000000000000000000000000000000000005354 168.0
TH2_k127_8044066_5 Domain of unknown function (DUF4010) - - - 0.000009178 50.0
TH2_k127_8048460_0 PFAM Ethanolamine ammonia lyase large subunit K03735 - 4.3.1.7 6.104e-196 626.0
TH2_k127_8048460_1 Belongs to the serpin family K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004085 277.0
TH2_k127_8048460_10 LamG domain protein jellyroll fold domain protein - - - 0.0004029 53.0
TH2_k127_8048460_2 PFAM BMC domain K04026 - - 0.000000000000000000000000000000000000000000000000000000000000003554 238.0
TH2_k127_8048460_3 Ethanolamine ammonia-lyase light chain (EutC) K03736 GO:0005575,GO:0005622,GO:0005623,GO:0009350,GO:0032991,GO:0044424,GO:0044464,GO:1902494 4.3.1.7 0.00000000000000000000000000000000000000000000000000002377 198.0
TH2_k127_8048460_4 Cobalamin adenosyltransferase K04032 - 2.5.1.17 0.000000000000000000000924 110.0
TH2_k127_8048460_5 Rubrerythrin K05919,K07798 - 1.15.1.2 0.0000000000000000156 87.0
TH2_k127_8048460_7 PFAM CBS domain containing protein - - - 0.00000000006138 68.0
TH2_k127_8048460_8 - - - - 0.000004201 57.0
TH2_k127_8048460_9 Involved in the tonB-independent uptake of proteins K01730,K03641 - 4.2.2.6 0.0003818 52.0
TH2_k127_8061919_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.657e-272 856.0
TH2_k127_8061919_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 472.0
TH2_k127_8061919_10 PFAM Phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000002016 158.0
TH2_k127_8061919_11 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000002746 154.0
TH2_k127_8061919_12 peptidyl-tyrosine sulfation - - - 0.00000000000004356 85.0
TH2_k127_8061919_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 377.0
TH2_k127_8061919_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 358.0
TH2_k127_8061919_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 301.0
TH2_k127_8061919_5 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000001555 216.0
TH2_k127_8061919_6 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000002282 218.0
TH2_k127_8061919_7 - - - - 0.00000000000000000000000000000000000000000000000000001063 196.0
TH2_k127_8061919_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000006851 158.0
TH2_k127_8061919_9 - - - - 0.00000000000000000000000000000000000000001587 160.0
TH2_k127_8090056_0 Periplasmic protein TonB links inner and outer membranes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 521.0
TH2_k127_8090056_1 protein containing a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 329.0
TH2_k127_8090056_2 Carboxypeptidase regulatory-like domain - - - 0.00000000001783 76.0
TH2_k127_8112652_0 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000007258 125.0
TH2_k127_8112652_1 COG1886 Flagellar motor switch type III secretory pathway protein K02416,K03225 - - 0.000000000000002196 88.0
TH2_k127_814061_0 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 628.0
TH2_k127_814061_1 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000001712 225.0
TH2_k127_814061_2 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000000000000000001092 136.0
TH2_k127_814061_3 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000000000003726 112.0
TH2_k127_8161300_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 371.0
TH2_k127_8161300_1 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 321.0
TH2_k127_8161300_2 - - - - 0.00000000000000000000000000000000000007476 159.0
TH2_k127_8161300_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000001983 121.0
TH2_k127_8161300_4 PilZ domain - - - 0.00000000000000000000000003211 112.0
TH2_k127_8173833_0 Flagellar Motor Protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 437.0
TH2_k127_8173833_2 50S ribosome-binding GTPase - - - 0.00000000000000000000000000000002492 144.0
TH2_k127_8173833_3 Transcriptional regulator - - - 0.000000000000000000000000000001755 132.0
TH2_k127_8173833_4 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000004036 130.0
TH2_k127_8173833_5 Transposase - - - 0.00000009462 59.0
TH2_k127_8173833_6 metallopeptidase activity K02674,K07114 - - 0.0000001969 63.0
TH2_k127_8173833_7 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000001882 59.0
TH2_k127_8173833_9 Unsaturated glucuronyl hydrolase - - - 0.0005913 44.0
TH2_k127_8175366_0 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 520.0
TH2_k127_8175366_1 DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008001 502.0
TH2_k127_8175366_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008156 261.0
TH2_k127_8175366_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000005783 231.0
TH2_k127_8175366_5 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000002257 228.0
TH2_k127_8175366_6 - - - - 0.00000000000000000000000000000000000000000000000000000000043 225.0
TH2_k127_8175366_7 PFAM Rhomboid family protein - - - 0.00000000000000000000000003265 119.0
TH2_k127_8175366_8 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000001359 118.0
TH2_k127_820367_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 4.409e-251 801.0
TH2_k127_820367_1 Tex-like protein N-terminal domain K06959 - - 5.035e-248 786.0
TH2_k127_820367_10 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 338.0
TH2_k127_820367_11 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 319.0
TH2_k127_820367_12 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 317.0
TH2_k127_820367_13 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009031 307.0
TH2_k127_820367_14 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 307.0
TH2_k127_820367_15 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005313 278.0
TH2_k127_820367_16 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003857 284.0
TH2_k127_820367_17 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000001388 269.0
TH2_k127_820367_18 Crp-like helix-turn-helix domain K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000236 236.0
TH2_k127_820367_19 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000005829 231.0
TH2_k127_820367_2 Amidohydrolase family - - - 1.82e-211 675.0
TH2_k127_820367_20 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000001676 240.0
TH2_k127_820367_21 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000001066 178.0
TH2_k127_820367_22 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000003224 168.0
TH2_k127_820367_23 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000000000009705 123.0
TH2_k127_820367_24 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000005896 105.0
TH2_k127_820367_25 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000001126 84.0
TH2_k127_820367_27 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.00000000008764 71.0
TH2_k127_820367_28 serine threonine protein kinase - - - 0.0000003993 60.0
TH2_k127_820367_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 603.0
TH2_k127_820367_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 541.0
TH2_k127_820367_5 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 435.0
TH2_k127_820367_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 384.0
TH2_k127_820367_7 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 368.0
TH2_k127_820367_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 357.0
TH2_k127_820367_9 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 349.0
TH2_k127_8228834_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.37e-224 717.0
TH2_k127_8228834_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 581.0
TH2_k127_8228834_10 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000223 252.0
TH2_k127_8228834_11 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000002036 231.0
TH2_k127_8228834_12 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000003256 213.0
TH2_k127_8228834_13 Thermolysin metallopeptidase, alpha-helical domain K01400,K08777 GO:0005575,GO:0005576 3.4.24.28 0.00000000000000000000000000000000000000000000000000000004042 218.0
TH2_k127_8228834_14 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000007338 203.0
TH2_k127_8228834_15 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000003609 205.0
TH2_k127_8228834_16 Thioesterase superfamily - - - 0.00000000000000000000000000000000000001498 150.0
TH2_k127_8228834_17 Putative metal-binding motif - - - 0.000000000000000000000000000002587 141.0
TH2_k127_8228834_18 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000003577 128.0
TH2_k127_8228834_19 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000001357 123.0
TH2_k127_8228834_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 527.0
TH2_k127_8228834_20 Tetratricopeptide repeat - - - 0.000000000000000000002964 106.0
TH2_k127_8228834_21 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000349 102.0
TH2_k127_8228834_22 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000004068 77.0
TH2_k127_8228834_23 PFAM Lantibiotic dehydratase K20483 - - 0.000000000004157 80.0
TH2_k127_8228834_25 extracellular matrix structural constituent - - - 0.0000006895 64.0
TH2_k127_8228834_26 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000001417 61.0
TH2_k127_8228834_3 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 488.0
TH2_k127_8228834_4 COG0006 Xaa-Pro aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 434.0
TH2_k127_8228834_5 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 398.0
TH2_k127_8228834_6 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 349.0
TH2_k127_8228834_7 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 304.0
TH2_k127_8228834_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 314.0
TH2_k127_8228834_9 Phosphoribulokinase / Uridine kinase family K00855,K00876 - 2.7.1.19,2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 287.0
TH2_k127_8287881_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.229e-270 859.0
TH2_k127_8287881_1 hydrolase of the alpha beta superfamily - - - 1.814e-247 791.0
TH2_k127_8287881_10 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000002034 131.0
TH2_k127_8287881_11 Domain of unknown function (DUF1287) K09974 - - 0.000000000000000000000000000148 126.0
TH2_k127_8287881_12 CRS1_YhbY K07574 - - 0.000000000000000000000276 106.0
TH2_k127_8287881_14 PFAM transposase IS3 IS911 family protein K07483 - - 0.000000000000000000008964 94.0
TH2_k127_8287881_15 - - - - 0.00000000000008809 74.0
TH2_k127_8287881_16 - - - - 0.000000000435 66.0
TH2_k127_8287881_17 - - - - 0.0000000006096 66.0
TH2_k127_8287881_18 import. Responsible for energy coupling to the transport system K10545,K17215 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015148,GO:0015749,GO:0015750,GO:0015753,GO:0017076,GO:0019321,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042732,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 0.000000001 63.0
TH2_k127_8287881_19 - - - - 0.000000008412 65.0
TH2_k127_8287881_2 D-isomer specific 2-hydroxyacid dehydrogenase K03778 - 1.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 436.0
TH2_k127_8287881_20 - - - - 0.0000001207 61.0
TH2_k127_8287881_21 Cytochrome c-type biogenesis protein K02200 - - 0.0002138 50.0
TH2_k127_8287881_3 HTH-like domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000173 280.0
TH2_k127_8287881_4 ATPase kinase involved in NAD metabolism - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000268 272.0
TH2_k127_8287881_5 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005593 280.0
TH2_k127_8287881_6 HTH-like domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000001146 230.0
TH2_k127_8287881_7 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000004232 159.0
TH2_k127_8287881_8 - - - - 0.0000000000000000000000000000000000002457 141.0
TH2_k127_8287881_9 Transposase mutator type - - - 0.000000000000000000000000000000000006329 147.0
TH2_k127_83176_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002002 256.0
TH2_k127_83176_1 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 0.0000000347 58.0
TH2_k127_832570_0 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 444.0
TH2_k127_832570_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102,K11103 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005222 254.0
TH2_k127_832570_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000001974 245.0
TH2_k127_8334976_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.757e-259 817.0
TH2_k127_8334976_1 Outer membrane receptor - - - 1.116e-242 780.0
TH2_k127_8334976_10 Peptidase, M61 - - - 0.0000000000000000000000000000000000000165 165.0
TH2_k127_8334976_11 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000004704 150.0
TH2_k127_8334976_12 OmpA family K02557 - - 0.000000000000000000006492 106.0
TH2_k127_8334976_14 TPR repeat - - - 0.0000000005101 69.0
TH2_k127_8334976_15 - - - - 0.0004873 52.0
TH2_k127_8334976_2 Belongs to the FtsK SpoIIIE SftA family K03466 - - 7.033e-224 724.0
TH2_k127_8334976_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.481e-217 696.0
TH2_k127_8334976_4 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 397.0
TH2_k127_8334976_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 347.0
TH2_k127_8334976_6 PFAM Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002106 272.0
TH2_k127_8334976_7 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000002629 234.0
TH2_k127_8334976_8 transposition K07497 - - 0.0000000000000000000000000000000000000000000000000000000000004963 223.0
TH2_k127_8341055_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000007438 216.0
TH2_k127_8341055_1 Domain of unknown function (DUF4382) - - - 0.0000000000000004667 86.0
TH2_k127_8341055_2 cellulose binding - - - 0.0000001774 62.0
TH2_k127_8342933_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.017e-246 771.0
TH2_k127_8342933_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.044e-219 707.0
TH2_k127_8342933_10 NAT, N-acetyltransferase, of N-acetylglutamate synthase K22478 - 2.3.1.1,2.7.2.8 0.00000000000000000000000000000000000000000000000000000004594 214.0
TH2_k127_8342933_11 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000006733 188.0
TH2_k127_8342933_12 PilZ domain - - - 0.0000000000000000000000000000000000002575 161.0
TH2_k127_8342933_13 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000005604 142.0
TH2_k127_8342933_14 succinate dehydrogenase K00241 - - 0.000000000000000000000000000000002285 142.0
TH2_k127_8342933_15 - - - - 0.0000001237 65.0
TH2_k127_8342933_2 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 3.674e-194 617.0
TH2_k127_8342933_3 O-methyltransferase K09846 - 2.1.1.210 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 540.0
TH2_k127_8342933_4 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 370.0
TH2_k127_8342933_5 Phospholipase D Active site motif K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 365.0
TH2_k127_8342933_6 PFAM Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 340.0
TH2_k127_8342933_7 Protein of unknown function (DUF2786) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 329.0
TH2_k127_8342933_8 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 306.0
TH2_k127_8342933_9 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000002197 217.0
TH2_k127_8357409_0 DEAD DEAH box K03724 - - 0.0 1507.0
TH2_k127_8357409_1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K12583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 515.0
TH2_k127_8357409_2 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 457.0
TH2_k127_8357409_3 Protein of unknown function (DUF979) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 324.0
TH2_k127_8357409_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003638 282.0
TH2_k127_8357409_5 Protein of unknown function (DUF969) - - - 0.000000000000000000000000000000000000000000000000000000000000000002804 242.0
TH2_k127_8357409_6 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.00000000000000000000002897 110.0
TH2_k127_8357409_7 Helix-turn-helix domain - - - 0.000000000000000000001319 98.0
TH2_k127_8365899_0 4Fe-4S dicluster domain K00184 - - 0.0 1066.0
TH2_k127_8365899_1 Nitrous oxide reductase K00376 - 1.7.2.4 3.384e-244 777.0
TH2_k127_8365899_2 Polysulphide reductase, NrfD K00185 - - 9.664e-237 741.0
TH2_k127_8365899_3 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 412.0
TH2_k127_8365899_4 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 301.0
TH2_k127_8365899_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000001459 229.0
TH2_k127_8365899_6 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000001424 197.0
TH2_k127_8365899_7 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000000000000009514 187.0
TH2_k127_8365899_8 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000095 168.0
TH2_k127_8365899_9 Cytochrome c - - - 0.00000000000000000000000001133 115.0
TH2_k127_8372569_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 8.546e-268 848.0
TH2_k127_8372569_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 519.0
TH2_k127_8372569_10 Peptidase M50B-like - - - 0.0000000000000000000000000000001799 134.0
TH2_k127_8372569_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000609 106.0
TH2_k127_8372569_12 Putative serine esterase (DUF676) K01046 - 3.1.1.3 0.00000000000000000000007838 110.0
TH2_k127_8372569_13 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000006298 81.0
TH2_k127_8372569_14 Domain of unknown function (DUF1956) - - - 0.0000000000004585 79.0
TH2_k127_8372569_15 Ribosomal protein L34 K02914 - - 0.000000001756 60.0
TH2_k127_8372569_16 TPR repeat - - - 0.000004891 58.0
TH2_k127_8372569_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 452.0
TH2_k127_8372569_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007651 417.0
TH2_k127_8372569_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 327.0
TH2_k127_8372569_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000000000000000000000000000000000000000000000000000000000005367 261.0
TH2_k127_8372569_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000001035 258.0
TH2_k127_8372569_8 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000006354 151.0
TH2_k127_8372569_9 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.000000000000000000000000000000007798 136.0
TH2_k127_8380703_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 316.0
TH2_k127_8380703_1 cog0421, spermidine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003293 284.0
TH2_k127_838822_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000576 283.0
TH2_k127_838822_1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000004851 165.0
TH2_k127_838822_2 helix_turn_helix, mercury resistance - - - 0.00000000000000000000002538 106.0
TH2_k127_8424779_0 PFAM Integrase catalytic region - - - 2.014e-227 716.0
TH2_k127_8424779_1 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 363.0
TH2_k127_8424779_2 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000000000000000000000000000000009086 203.0
TH2_k127_8424779_3 COG3547 Transposase and inactivated derivatives - - - 0.00000000001369 66.0
TH2_k127_8435539_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 517.0
TH2_k127_8435539_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 295.0
TH2_k127_8435539_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000001468 151.0
TH2_k127_8447_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.09e-268 833.0
TH2_k127_8447_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 484.0
TH2_k127_8447_2 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000000003737 199.0
TH2_k127_8447_3 PFAM PEGA domain - - - 0.0000000001135 74.0
TH2_k127_8476470_0 FAD dependent oxidoreductase central domain - - - 0.0 1155.0
TH2_k127_8476470_1 acyl-coa dehydrogenase K09456 - - 6.833e-271 865.0
TH2_k127_8476470_2 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 391.0
TH2_k127_8476470_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000001357 241.0
TH2_k127_8476470_4 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000001304 237.0
TH2_k127_8476470_5 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000005426 231.0
TH2_k127_8476470_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000027 149.0
TH2_k127_8476470_7 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000005178 121.0
TH2_k127_8476470_8 Rhomboid family K19225 - 3.4.21.105 0.000000000000000119 94.0
TH2_k127_8476470_9 TonB family K03646,K03832 - - 0.000000191 61.0
TH2_k127_8489361_0 proteins of the AP superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 552.0
TH2_k127_8489361_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 351.0
TH2_k127_8489361_10 response to copper ion K01187,K16915 - 3.2.1.20 0.0000000000000000000000000000000000001736 162.0
TH2_k127_8489361_11 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000005695 140.0
TH2_k127_8489361_12 Hemolysin TlyA K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.00000000000000001005 96.0
TH2_k127_8489361_13 YceI-like domain - - - 0.0000000004914 62.0
TH2_k127_8489361_14 belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000001707 60.0
TH2_k127_8489361_2 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 349.0
TH2_k127_8489361_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 327.0
TH2_k127_8489361_4 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 302.0
TH2_k127_8489361_5 2OG-Fe dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001072 287.0
TH2_k127_8489361_6 Polysaccharide biosynthesis protein K03328 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003316 269.0
TH2_k127_8489361_7 - - - - 0.0000000000000000000000000000000000000000000000003416 184.0
TH2_k127_8489361_8 Cytochrome c - - - 0.0000000000000000000000000000000000000000000804 168.0
TH2_k127_8489361_9 - - - - 0.0000000000000000000000000000000000001448 154.0
TH2_k127_850960_0 COG0618 Exopolyphosphatase-related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001094 286.0
TH2_k127_850960_1 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000001959 166.0
TH2_k127_850960_2 membrane K08973 - - 0.000000000005188 73.0
TH2_k127_850960_3 TPR repeat - - - 0.00004114 55.0
TH2_k127_8554143_0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 356.0
TH2_k127_8554143_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 363.0
TH2_k127_8554143_2 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001296 269.0
TH2_k127_8554143_3 pfkB family carbohydrate kinase - - - 0.00000000000000103 80.0
TH2_k127_8554143_4 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000006467 77.0
TH2_k127_8592389_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 584.0
TH2_k127_8592389_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 503.0
TH2_k127_8592389_10 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000004722 116.0
TH2_k127_8592389_11 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000003592 73.0
TH2_k127_8592389_2 Belongs to the pseudouridine synthase RluA family K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 311.0
TH2_k127_8592389_3 Enoyl-(Acyl carrier protein) reductase K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002284 293.0
TH2_k127_8592389_4 Flagellar basal body rod K02396,K03333 - 1.1.3.6 0.00000000000000000000000000000000000000000000006418 184.0
TH2_k127_8592389_5 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000001033 177.0
TH2_k127_8592389_6 Cytochrome c oxidase subunit K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000003684 167.0
TH2_k127_8592389_7 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000049 165.0
TH2_k127_8592389_8 Flagellar basal body rod K02396 - - 0.0000000000000000000000000000000000002248 156.0
TH2_k127_8594375_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.945e-294 917.0
TH2_k127_8594375_1 DEAD/H associated K03724 - - 7.323e-249 801.0
TH2_k127_8594375_2 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 613.0
TH2_k127_8594375_3 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 394.0
TH2_k127_8594375_4 TIGRFAM phytoene desaturase K09845 - 1.3.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 361.0
TH2_k127_8594375_5 High confidence in function and specificity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 302.0
TH2_k127_8594375_6 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000003971 238.0
TH2_k127_8594375_7 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000003944 209.0
TH2_k127_8594375_8 Tryptophan halogenase - - - 0.0000000000000000000000000000000000009373 157.0
TH2_k127_8594375_9 TPR repeat - - - 0.000002121 58.0
TH2_k127_8595211_0 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001297 279.0
TH2_k127_8595211_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000002201 161.0
TH2_k127_8595211_2 - K07112 - - 0.00000000000000000000000000001081 124.0
TH2_k127_8595211_3 Sulphur transport K07112 - - 0.00000000000000000000000183 113.0
TH2_k127_8595211_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000792 96.0
TH2_k127_8607006_0 Radical SAM superfamily K06139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 429.0
TH2_k127_8607006_1 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 398.0
TH2_k127_8607006_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 347.0
TH2_k127_8607006_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001155 282.0
TH2_k127_8607006_4 Putative exonuclease SbcCD, C subunit - - - 0.00000000000000000002157 106.0
TH2_k127_8607006_5 protein trimerization - - - 0.0000000000000000001488 104.0
TH2_k127_8607945_0 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 556.0
TH2_k127_8615393_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000005346 164.0
TH2_k127_8615393_2 Domain of unknown function (DUF2520) - - - 0.000000003137 68.0
TH2_k127_8642061_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 1.239e-226 711.0
TH2_k127_8642061_1 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 540.0
TH2_k127_8642061_10 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000001467 184.0
TH2_k127_8642061_11 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000811 187.0
TH2_k127_8642061_12 membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000001674 151.0
TH2_k127_8642061_13 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000000000005389 162.0
TH2_k127_8642061_14 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000005658 156.0
TH2_k127_8642061_15 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000003083 148.0
TH2_k127_8642061_16 Protein of unknown function (DUF3999) - - - 0.00000000000000000000000000004867 135.0
TH2_k127_8642061_17 STAS domain K04749 - - 0.0000000000000000001249 92.0
TH2_k127_8642061_18 Adenosine/AMP deaminase K01488 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4 0.00000000000000002486 97.0
TH2_k127_8642061_19 Outer membrane efflux protein K12340 - - 0.00000006352 66.0
TH2_k127_8642061_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 419.0
TH2_k127_8642061_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 380.0
TH2_k127_8642061_4 desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 361.0
TH2_k127_8642061_5 ABC transporter, ATP-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 335.0
TH2_k127_8642061_6 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006125 302.0
TH2_k127_8642061_7 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006173 278.0
TH2_k127_8642061_8 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001794 276.0
TH2_k127_8642061_9 FHA domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003545 280.0
TH2_k127_8652082_0 COG0451 Nucleoside-diphosphate-sugar epimerases K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 444.0
TH2_k127_8652082_1 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001118 287.0
TH2_k127_8652082_2 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000005184 94.0
TH2_k127_8671693_0 TIGRFAM geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.0000000000000000000000000000000000000000000000000000001141 206.0
TH2_k127_8691303_0 topoisomerase K02469 - 5.99.1.3 4.804e-294 920.0
TH2_k127_8691303_1 DNA topoisomerase K02470,K02622 - 5.99.1.3 8.856e-274 855.0
TH2_k127_8691303_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000004241 109.0
TH2_k127_8691303_11 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000001958 72.0
TH2_k127_8691303_12 Asparaginase K13051 - 3.4.19.5 0.00001912 52.0
TH2_k127_8691303_13 endopeptidase activity - - - 0.0005388 52.0
TH2_k127_8691303_2 Belongs to the glycosyl hydrolase 13 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 581.0
TH2_k127_8691303_3 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 562.0
TH2_k127_8691303_4 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 504.0
TH2_k127_8691303_5 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 418.0
TH2_k127_8691303_6 glucan 1,4-alpha-glucosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 381.0
TH2_k127_8691303_7 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000002862 271.0
TH2_k127_8691303_8 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000219 213.0
TH2_k127_8691303_9 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000002894 123.0
TH2_k127_8697513_0 PFAM MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 591.0
TH2_k127_8697513_1 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002029 264.0
TH2_k127_8697513_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000007334 253.0
TH2_k127_8697513_3 Type II IV secretion system protein K02283,K03609 - - 0.00000000000000000000000000000000000000000000000001423 188.0
TH2_k127_8697513_4 Kelch motif - - - 0.0000000000000000000004833 112.0
TH2_k127_8711878_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.415e-208 653.0
TH2_k127_8711878_1 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002866 294.0
TH2_k127_8711878_2 leucine-zipper of insertion element IS481 - - - 0.0000000000000000003228 94.0
TH2_k127_8714719_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family K13687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004211 305.0
TH2_k127_8714719_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000002418 63.0
TH2_k127_8726531_0 GMC oxidoreductase K03333 - 1.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 616.0
TH2_k127_8726531_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 514.0
TH2_k127_8726531_2 sulfuric ester hydrolase activity K03760,K19353 - 2.7.8.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 302.0
TH2_k127_8726531_3 TIGRFAM YD repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003283 278.0
TH2_k127_8726531_4 AAA domain - - - 0.0000000000000000000000000001047 117.0
TH2_k127_8729150_0 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 440.0
TH2_k127_8729150_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001888 284.0
TH2_k127_8729150_2 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000002962 61.0
TH2_k127_8729150_3 Cell division protein FtsL - - - 0.0007626 51.0
TH2_k127_8735967_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 1300.0
TH2_k127_8735967_1 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 553.0
TH2_k127_8735967_10 lyase activity - - - 0.00000000000000000000002687 113.0
TH2_k127_8735967_11 Cell surface receptor IPT TIG - - - 0.0000006999 59.0
TH2_k127_8735967_2 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000036 278.0
TH2_k127_8735967_3 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001476 261.0
TH2_k127_8735967_4 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000000000000003496 246.0
TH2_k127_8735967_5 RelA SpoT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000004667 224.0
TH2_k127_8735967_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000003367 191.0
TH2_k127_8735967_7 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000002288 189.0
TH2_k127_8735967_8 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000005059 181.0
TH2_k127_8735967_9 Protein kinase; unclassified specificity. K12132 - 2.7.11.1 0.0000000000000000000000000000006822 134.0
TH2_k127_873954_0 PFAM asparagine synthase K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 323.0
TH2_k127_873954_1 DTW K05812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006446 263.0
TH2_k127_873954_10 domain, Protein - - - 0.0002058 53.0
TH2_k127_873954_2 Scramblase - - - 0.0000000000000000000000000000000000000000000000008749 183.0
TH2_k127_873954_3 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.000000000000000000000000000000000000000000001596 176.0
TH2_k127_873954_4 leucine binding - - - 0.00000000000000000000000000000000000125 153.0
TH2_k127_873954_5 - - - - 0.000000000000000000000000000007618 122.0
TH2_k127_873954_6 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000005509 123.0
TH2_k127_873954_7 JAB/MPN domain K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000006014 113.0
TH2_k127_873954_8 Copper binding proteins, plastocyanin/azurin family - - - 0.00000007631 61.0
TH2_k127_873954_9 alcohol dehydrogenase K11337 - 1.1.1.396 0.0000001716 61.0
TH2_k127_8748655_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.78e-215 685.0
TH2_k127_8748655_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.119e-208 661.0
TH2_k127_8748655_10 cheY-homologous receiver domain K07773 - - 0.000000000000000000000000000000000009917 141.0
TH2_k127_8748655_11 Belongs to the bacterial histone-like protein family K05788 - - 0.000000000000000000000000000000001893 134.0
TH2_k127_8748655_12 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000001873 121.0
TH2_k127_8748655_14 Worm-specific repeat type 1 - - - 0.000008888 57.0
TH2_k127_8748655_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 536.0
TH2_k127_8748655_3 3-oxoacid CoA-transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 332.0
TH2_k127_8748655_4 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 320.0
TH2_k127_8748655_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002472 286.0
TH2_k127_8748655_6 PFAM chorismate K01665 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000001594 261.0
TH2_k127_8748655_7 Transcriptional regulator, CarD family K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000291 244.0
TH2_k127_8748655_8 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000004091 233.0
TH2_k127_8748655_9 Transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000001374 221.0
TH2_k127_8772900_0 Peptidase C39 family K12541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 358.0
TH2_k127_8772900_1 COG0845 membrane-fusion protein - - - 0.0000000000000000000000000000000000000000000000004826 184.0
TH2_k127_8772900_2 Winged helix-turn-helix DNA-binding - - - 0.0000000000000000000000000000000008743 133.0
TH2_k127_8782347_0 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 366.0
TH2_k127_8782347_1 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 370.0
TH2_k127_8782347_2 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001978 261.0
TH2_k127_8782347_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000004573 227.0
TH2_k127_8782347_4 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000001529 188.0
TH2_k127_8782347_5 Tetratricopeptide repeat - - - 0.00000000000000000000005888 115.0
TH2_k127_8782347_7 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0001413 51.0
TH2_k127_8844538_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005475 286.0
TH2_k127_8845728_0 translation initiation factor activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000001363 169.0
TH2_k127_8845728_1 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000000000000000000000000795 163.0
TH2_k127_8848408_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0000049,GO:0000166,GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046983,GO:0070905,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 499.0
TH2_k127_8848408_1 repeat protein - - - 0.000000000000000000000000000000000000000000000000000006654 220.0
TH2_k127_8848408_2 Domain of unknown function (DUF2383) - - - 0.000000000000000000000000000000000000000000004642 173.0
TH2_k127_8848408_3 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0000000000000000000000000000000000000000002616 163.0
TH2_k127_8848408_4 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000000000000000002598 157.0
TH2_k127_8848408_5 PFAM PRC-barrel - - - 0.000000000000000000000000001345 120.0
TH2_k127_8848408_6 - - - - 0.00000002587 64.0
TH2_k127_8848408_7 Tetratricopeptide repeat - - - 0.00000008798 68.0
TH2_k127_8848408_8 Transposase IS4 family protein - - - 0.0003133 43.0
TH2_k127_8900664_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 2.735e-213 689.0
TH2_k127_8900664_1 ABC transporter, ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 509.0
TH2_k127_8900664_2 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000004806 238.0
TH2_k127_8900664_3 NnrS protein K07234 - - 0.00000000000000000000000000000000000000000000001219 187.0
TH2_k127_8900664_4 CBS domain containing protein K07168 - - 0.00000001079 64.0
TH2_k127_8900856_0 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 474.0
TH2_k127_8900856_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000001553 279.0
TH2_k127_8900856_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000006447 226.0
TH2_k127_8900856_3 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000168 204.0
TH2_k127_8900856_4 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000000000000000001436 160.0
TH2_k127_8900856_5 protein SCO1 SenC K07152 - - 0.000000000000000000000000000000002248 139.0
TH2_k127_8900856_6 Phosphoglycerate mutase family - - - 0.000000000000000000000000004451 120.0
TH2_k127_8900856_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000005776 117.0
TH2_k127_8900856_8 PQQ-like domain - - - 0.000005367 48.0
TH2_k127_890169_0 PFAM isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 5.727e-200 635.0
TH2_k127_890169_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000001073 215.0
TH2_k127_89142_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 338.0
TH2_k127_89142_1 DNA RNA non-specific endonuclease K01173 - - 0.00000000000000000000000000000000000000000000034 185.0
TH2_k127_89142_2 Inositol monophosphatase family K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000004982 175.0
TH2_k127_89142_3 PPE family - - - 0.00000002403 64.0
TH2_k127_89142_4 Cold-shock protein K03704 - - 0.0000004096 63.0
TH2_k127_89142_5 Belongs to the glycosyl hydrolase family 6 - - - 0.000004301 56.0
TH2_k127_89142_6 Tfp pilus assembly protein FimV - - - 0.0006094 51.0
TH2_k127_89142_7 Serine aminopeptidase, S33 K19311 GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016298,GO:0016787,GO:0016788,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0072329,GO:0104004,GO:1901575 - 0.0007971 51.0
TH2_k127_910859_0 sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 400.0
TH2_k127_910859_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000008105 204.0
TH2_k127_910859_2 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000001447 164.0
TH2_k127_910859_3 - - - - 0.00000000000000000000000004364 121.0
TH2_k127_912490_0 Cation transporting ATPase, C-terminus K01537 - 3.6.3.8 3.498e-290 924.0
TH2_k127_912490_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 9.693e-275 854.0
TH2_k127_912490_10 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 369.0
TH2_k127_912490_11 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000854 343.0
TH2_k127_912490_12 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000127 284.0
TH2_k127_912490_13 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008734 271.0
TH2_k127_912490_14 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001924 258.0
TH2_k127_912490_15 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000375 250.0
TH2_k127_912490_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000001939 247.0
TH2_k127_912490_17 COG3911 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000001743 229.0
TH2_k127_912490_18 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K00882,K00917 - 2.7.1.144,2.7.1.56 0.00000000000000000000000000000000000000000000000000000000001601 221.0
TH2_k127_912490_19 bacterial OsmY and nodulation domain - - - 0.0000000000000000000000000000000000000000000000001441 184.0
TH2_k127_912490_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.26e-249 783.0
TH2_k127_912490_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000001618 112.0
TH2_k127_912490_21 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000003838 119.0
TH2_k127_912490_22 Universal stress protein family - - - 0.000000000000000000000004638 107.0
TH2_k127_912490_23 Universal stress protein family - - - 0.00000000000000000000001699 107.0
TH2_k127_912490_24 - - - - 0.0000000000000000001584 98.0
TH2_k127_912490_25 Phosphopantetheine attachment site - - - 0.000000000000000009361 87.0
TH2_k127_912490_26 PFAM NHL repeat containing protein - - - 0.0000000000000000186 97.0
TH2_k127_912490_27 YXWGXW repeat (2 copies) - - - 0.0000000000000002371 89.0
TH2_k127_912490_28 response regulator K02481,K07713 - - 0.000000000000007732 80.0
TH2_k127_912490_29 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000002457 76.0
TH2_k127_912490_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 5.233e-247 779.0
TH2_k127_912490_30 DnaK suppressor protein - - - 0.00000003429 63.0
TH2_k127_912490_31 - - - - 0.00000007266 65.0
TH2_k127_912490_4 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 498.0
TH2_k127_912490_5 Protoglobin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 473.0
TH2_k127_912490_6 FAD binding domain K09828 - 1.3.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 481.0
TH2_k127_912490_7 (ABC) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 439.0
TH2_k127_912490_8 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 423.0
TH2_k127_912490_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 393.0
TH2_k127_916019_0 General secretory system II, protein E domain protein K02652 - - 2.618e-246 771.0
TH2_k127_916019_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 528.0
TH2_k127_916019_11 - - - - 0.00000000000000000000000001054 112.0
TH2_k127_916019_14 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000135 61.0
TH2_k127_916019_2 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 471.0
TH2_k127_916019_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 426.0
TH2_k127_916019_4 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 385.0
TH2_k127_916019_5 Histidine kinase K02668,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 324.0
TH2_k127_916019_6 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000659 255.0
TH2_k127_916019_7 alcohol dehydrogenase K18012 - 1.4.1.11 0.00000000000000000000000000000000000000000000001239 180.0
TH2_k127_916019_8 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000438 176.0
TH2_k127_916019_9 Belongs to the ompA family - - - 0.000000000000000000000000000000000006379 150.0
TH2_k127_948760_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 8.538e-204 666.0
TH2_k127_948760_1 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000001559 201.0
TH2_k127_948760_2 Belongs to the UPF0761 family K07058 - - 0.000000000000000000000000000000000000000001923 167.0
TH2_k127_948760_3 - - - - 0.000000000000000000000000001425 128.0
TH2_k127_969139_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007622 582.0
TH2_k127_969139_1 Exodeoxyribonuclease V, gamma subunit K03583 - 3.1.11.5 0.00000000000000000000000000000000000000000178 171.0
TH2_k127_969139_2 Tetratricopeptide repeat - - - 0.000001109 61.0
TH2_k127_982687_0 PFAM Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 415.0
TH2_k127_982687_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 408.0
TH2_k127_982687_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 385.0
TH2_k127_982687_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005207 281.0
TH2_k127_982687_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002308 267.0
TH2_k127_982687_5 similarity to GP 17427840 K07497 - - 0.0000000000000000000000000000000000000000000000000000000002002 207.0
TH2_k127_982687_6 COG4584 Transposase and inactivated derivatives - - - 0.0000000000000000000000432 104.0
TH2_k127_982687_7 Homeodomain-like domain - - - 0.00000000000000000002135 104.0