Overview

ID MAG03922
Name TH2_bin.61
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order Thermoanaerobaculales
Family Thermoanaerobaculaceae
Genus
Species
Assembly information
Completeness (%) 58.88
Contamination (%) 0.1
GC content (%) 71.0
N50 (bp) 5,139
Genome size (bp) 1,722,373

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1647

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1028397_0 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 318.0
TH2_k127_1028397_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000002998 181.0
TH2_k127_1028397_2 branched-chain amino acid K01995 - - 0.0000000000000000000000000000000000000000003472 159.0
TH2_k127_1042396_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 424.0
TH2_k127_1045484_0 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000222 105.0
TH2_k127_1045484_1 general secretion pathway protein G K02456 - - 0.00000001825 62.0
TH2_k127_1045484_2 O-antigen ligase like membrane protein K18814 - - 0.000002097 61.0
TH2_k127_1045484_3 Bacterial membrane protein, YfhO - - - 0.00008145 53.0
TH2_k127_1067866_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 565.0
TH2_k127_1067866_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 293.0
TH2_k127_1067866_2 4 iron, 4 sulfur cluster binding K18356 - 1.2.1.58 0.00000000000000000000000000001706 124.0
TH2_k127_1128477_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 400.0
TH2_k127_1128477_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 331.0
TH2_k127_1128477_2 pfam abc K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006852 257.0
TH2_k127_1128477_3 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008688 255.0
TH2_k127_1128477_4 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000203 263.0
TH2_k127_1128477_5 von Willebrand factor, type A - - - 0.000000000000000000000000000000000003482 157.0
TH2_k127_1128477_6 HDOD domain K07814 - - 0.0000000000001665 84.0
TH2_k127_1128477_7 lyase activity - - - 0.000000000001101 81.0
TH2_k127_1132597_0 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 607.0
TH2_k127_1132597_1 Glutamate formimidoyltransferase K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 554.0
TH2_k127_1132597_10 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000001072 235.0
TH2_k127_1132597_11 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000001236 218.0
TH2_k127_1132597_12 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000009661 227.0
TH2_k127_1132597_13 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000065 218.0
TH2_k127_1132597_14 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000406 211.0
TH2_k127_1132597_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000001312 121.0
TH2_k127_1132597_16 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000002461 132.0
TH2_k127_1132597_17 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000256 107.0
TH2_k127_1132597_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 514.0
TH2_k127_1132597_3 ADP-glyceromanno-heptose 6-epimerase activity K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 471.0
TH2_k127_1132597_4 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 442.0
TH2_k127_1132597_5 TIGRFAM glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 361.0
TH2_k127_1132597_6 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 315.0
TH2_k127_1132597_7 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 310.0
TH2_k127_1132597_8 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002685 252.0
TH2_k127_1132597_9 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000726 257.0
TH2_k127_1136787_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 4.376e-276 876.0
TH2_k127_1136787_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000004787 271.0
TH2_k127_1136787_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000006795 227.0
TH2_k127_1136787_3 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000001437 195.0
TH2_k127_1136787_4 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000002735 112.0
TH2_k127_1136787_5 outer membrane autotransporter barrel domain protein - - - 0.0000000002805 68.0
TH2_k127_1141066_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 616.0
TH2_k127_1159901_0 symporter activity K03307,K11928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 509.0
TH2_k127_1159901_1 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 350.0
TH2_k127_1159901_2 PFAM peptidase M24 - - - 0.00000000000000000000000000000000000003228 145.0
TH2_k127_1186247_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.122e-272 862.0
TH2_k127_1186247_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.912e-260 841.0
TH2_k127_1186247_10 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000692 152.0
TH2_k127_1186247_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000666 125.0
TH2_k127_1186247_12 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000005496 81.0
TH2_k127_1186247_13 Polymer-forming cytoskeletal - - - 0.0000000000006362 80.0
TH2_k127_1186247_14 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000007043 73.0
TH2_k127_1186247_15 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000007843 67.0
TH2_k127_1186247_17 aminotransferase class I and II - - - 0.00000004569 57.0
TH2_k127_1186247_2 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 602.0
TH2_k127_1186247_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 384.0
TH2_k127_1186247_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 288.0
TH2_k127_1186247_5 Chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009574 283.0
TH2_k127_1186247_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008864 261.0
TH2_k127_1186247_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000002319 246.0
TH2_k127_1186247_8 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000003651 224.0
TH2_k127_1186247_9 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000002431 201.0
TH2_k127_1192457_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 485.0
TH2_k127_1192457_1 Aldehyde dehydrogenase (NAD) family protein K13922 - 1.2.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 456.0
TH2_k127_1192457_10 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000000000000115 115.0
TH2_k127_1192457_11 Tetratricopeptide repeat - - - 0.000000000000000000000593 107.0
TH2_k127_1192457_12 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000006033 101.0
TH2_k127_1192457_13 Biopolymer transport protein K03559,K03560 - - 0.000000000000000000002284 99.0
TH2_k127_1192457_14 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000001614 93.0
TH2_k127_1192457_15 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000006609 96.0
TH2_k127_1192457_16 BMC - - - 0.00000000000000001795 90.0
TH2_k127_1192457_17 Ethanolamine utilisation protein EutN/carboxysome K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000000000000002591 88.0
TH2_k127_1192457_18 Protein of unknown function (DUF4013) - - - 0.0000006427 59.0
TH2_k127_1192457_2 BMC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002845 278.0
TH2_k127_1192457_3 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001905 264.0
TH2_k127_1192457_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000007489 261.0
TH2_k127_1192457_5 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000001409 234.0
TH2_k127_1192457_6 Putative molybdenum carrier - - - 0.00000000000000000000000000000000000000000008481 180.0
TH2_k127_1192457_7 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.00000000000000000000000000000000003518 149.0
TH2_k127_1192457_8 COGs COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.00000000000000000000000000000001048 130.0
TH2_k127_1192457_9 aminopeptidase activity - - - 0.00000000000000000000000000000006597 136.0
TH2_k127_1208051_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 585.0
TH2_k127_1208051_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 428.0
TH2_k127_1208051_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 405.0
TH2_k127_1208051_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000001736 162.0
TH2_k127_1208051_4 DoxX - - - 0.000000000000000000000000004178 124.0
TH2_k127_1208051_5 PFAM Peptidase M23 - - - 0.000000000000000004513 93.0
TH2_k127_1208051_6 Belongs to the UPF0312 family - - - 0.00003284 54.0
TH2_k127_1209929_0 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 566.0
TH2_k127_1209929_1 TIGRFAM cysteine desulfurase family protein, VC1184 subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 489.0
TH2_k127_1209929_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 326.0
TH2_k127_1209929_3 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001046 292.0
TH2_k127_1209929_4 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000002442 243.0
TH2_k127_1209929_5 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000004514 173.0
TH2_k127_1215094_0 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 304.0
TH2_k127_1215094_1 Glycosyl transferases group 1 - - - 0.00000000000000000007508 99.0
TH2_k127_121780_0 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 355.0
TH2_k127_121780_1 PFAM Stage II sporulation E family protein K01079,K07315 - 3.1.3.3 0.00000000000000000000000000000000000000002137 174.0
TH2_k127_121780_2 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000003108 123.0
TH2_k127_121780_3 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000003973 95.0
TH2_k127_1220634_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1437.0
TH2_k127_1220634_1 Domain of unknown function (DUF1820) - - - 0.00000000000000000000000000000000207 139.0
TH2_k127_1220634_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000939 106.0
TH2_k127_1220634_3 histone H2A K63-linked ubiquitination K02283,K03466 - - 0.0000002903 60.0
TH2_k127_1228413_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.351e-302 946.0
TH2_k127_1228413_1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006465 265.0
TH2_k127_1228413_2 PFAM Hemerythrin HHE cation binding domain protein - - - 0.00000000000000000000000000000000000000000000006466 177.0
TH2_k127_1228413_3 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.00000000000000000000000000000000000000155 164.0
TH2_k127_1228413_4 Transcriptional regulator - - - 0.00000000000000000000002217 104.0
TH2_k127_1228413_5 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000002927 74.0
TH2_k127_1228413_6 response to copper ion - - - 0.0001549 52.0
TH2_k127_1248386_0 Phosphoesterase family - - - 7.536e-213 689.0
TH2_k127_1248386_1 peptidase S9 prolyl oligopeptidase active site K01278 - 3.4.14.5 4.842e-209 671.0
TH2_k127_1248386_2 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000002841 243.0
TH2_k127_1259624_0 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 452.0
TH2_k127_1259624_1 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 431.0
TH2_k127_1259624_2 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 396.0
TH2_k127_1259624_3 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000008201 98.0
TH2_k127_1259624_4 oxidoreductase activity - - - 0.0000000000000001531 94.0
TH2_k127_1259624_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000376 64.0
TH2_k127_128779_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5e-324 1001.0
TH2_k127_128779_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 561.0
TH2_k127_128779_2 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 455.0
TH2_k127_1289914_0 PEP-CTERM motif - - - 0.00000000000000000157 95.0
TH2_k127_1289914_1 lipolytic protein G-D-S-L family K00983 - 2.7.7.43 0.00000000000000001329 87.0
TH2_k127_1301088_0 Peptidase M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 516.0
TH2_k127_1301088_1 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 472.0
TH2_k127_1301088_2 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 383.0
TH2_k127_1301088_3 Putative adhesin - - - 0.0000000000002304 83.0
TH2_k127_1301088_4 Periplasmic or secreted lipoprotein K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.000000002338 69.0
TH2_k127_1301088_6 OmpW family K07275 - - 0.00001816 55.0
TH2_k127_1307500_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 478.0
TH2_k127_1307500_1 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000299 210.0
TH2_k127_1307500_2 DinB family - - - 0.0000000000000000000000000000000000000000000000003722 180.0
TH2_k127_1307500_3 OmpA family K03640 - - 0.0000000000000000000000000000004112 136.0
TH2_k127_1349192_0 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000009259 190.0
TH2_k127_1349192_1 ApaG domain K06195 - - 0.00000000000000000000000000000000000000233 165.0
TH2_k127_1349192_3 Alpha/beta hydrolase of unknown function (DUF1057) - - - 0.000000003247 61.0
TH2_k127_1349192_4 PFAM Rhomboid family - - - 0.0005392 52.0
TH2_k127_1350803_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2.026e-277 875.0
TH2_k127_1350803_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 359.0
TH2_k127_1350803_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000001109 140.0
TH2_k127_1350803_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000000000001932 92.0
TH2_k127_1379151_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.945e-211 681.0
TH2_k127_1379151_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.644e-194 638.0
TH2_k127_1379151_2 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000001411 224.0
TH2_k127_1379151_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000002834 231.0
TH2_k127_1379151_4 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000002212 203.0
TH2_k127_1379151_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000005526 127.0
TH2_k127_1379151_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000006814 85.0
TH2_k127_1379151_7 Protein of unknown function (DUF503) K09764 - - 0.000000002 63.0
TH2_k127_147408_0 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001002 278.0
TH2_k127_147408_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000009704 246.0
TH2_k127_147408_2 membrane - - - 0.000000000000000000000000000000000000000009613 164.0
TH2_k127_147408_3 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000000000000006271 155.0
TH2_k127_147408_4 Cytochrome c554 and c-prime - - - 0.0000000000000001178 91.0
TH2_k127_147408_5 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000002805 62.0
TH2_k127_1478143_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 357.0
TH2_k127_1478143_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 293.0
TH2_k127_1478143_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000008964 264.0
TH2_k127_1478143_3 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000006513 254.0
TH2_k127_1478143_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000007623 199.0
TH2_k127_1478143_5 Winged helix-turn-helix domain (DUF2582) - - - 0.000000002085 61.0
TH2_k127_1501556_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 409.0
TH2_k127_1501556_1 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000002309 122.0
TH2_k127_1501556_2 lipid A biosynthetic process K00973,K02414,K21449 - 2.7.7.24 0.0000000000000001438 86.0
TH2_k127_1521192_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 549.0
TH2_k127_1521192_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 374.0
TH2_k127_1521192_2 PFAM Uncharacterised conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007524 272.0
TH2_k127_1533065_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 598.0
TH2_k127_1533065_1 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 304.0
TH2_k127_1533065_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000001434 214.0
TH2_k127_1533065_3 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000000000000579 208.0
TH2_k127_1533065_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000005437 72.0
TH2_k127_156386_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 378.0
TH2_k127_156386_1 Domain of unknown function (DUF3391) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 304.0
TH2_k127_156386_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001723 297.0
TH2_k127_1580612_0 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003023 282.0
TH2_k127_1580612_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.0000000000000000000000000000000000000000000002853 172.0
TH2_k127_1580612_2 Response regulator receiver - - - 0.000000000000000000000000000000000000000000009043 186.0
TH2_k127_1580612_3 DinB family - - - 0.000000000000000000000000000000000000002234 155.0
TH2_k127_1580612_4 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.00000000000000000002506 98.0
TH2_k127_1580612_5 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.00000000000007421 76.0
TH2_k127_1584474_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 552.0
TH2_k127_1584474_1 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 426.0
TH2_k127_1584474_2 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 314.0
TH2_k127_1584474_3 Fumarase C-terminus K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000131 155.0
TH2_k127_1584474_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding K00176 - 1.2.7.3 0.00000000000000000000005756 110.0
TH2_k127_1584474_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000005114 91.0
TH2_k127_163063_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1005.0
TH2_k127_1631231_0 Oligoendopeptidase f - - - 2.995e-206 658.0
TH2_k127_1631231_1 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 541.0
TH2_k127_1631231_2 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 382.0
TH2_k127_1636496_0 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 316.0
TH2_k127_1636496_1 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002175 259.0
TH2_k127_1636496_2 Predicted membrane protein (DUF2061) - - - 0.0000000000000000000005678 98.0
TH2_k127_1639236_0 outer membrane efflux protein - - - 0.0000000000000000000000002683 114.0
TH2_k127_1639236_1 Yip1 domain - - - 0.0000000000003517 79.0
TH2_k127_1639236_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000001729 57.0
TH2_k127_1644848_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1042.0
TH2_k127_1644848_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 636.0
TH2_k127_1644848_2 Sodium:sulfate symporter transmembrane region K14445 - - 0.000001449 50.0
TH2_k127_167212_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 516.0
TH2_k127_167212_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000003136 145.0
TH2_k127_169018_0 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000006458 124.0
TH2_k127_169018_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000003088 57.0
TH2_k127_169018_2 cyclic nucleotide-binding K10914 - - 0.00001842 57.0
TH2_k127_169018_3 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.00002064 51.0
TH2_k127_1695484_0 homocysteine catabolic process K01372,K02316 - 3.4.22.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 404.0
TH2_k127_1695484_1 PFAM Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 328.0
TH2_k127_1695484_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000004763 165.0
TH2_k127_1695484_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000005976 169.0
TH2_k127_1695484_4 bacterial-type flagellum-dependent cell motility - - - 0.00000000436 65.0
TH2_k127_172370_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000535 200.0
TH2_k127_172370_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000001037 179.0
TH2_k127_172370_2 Transcriptional regulatory protein, C terminal - - - 0.00000000351 69.0
TH2_k127_172370_3 Histidine kinase - - - 0.0002491 51.0
TH2_k127_1725883_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 439.0
TH2_k127_1725883_1 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 370.0
TH2_k127_1725883_10 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000005645 68.0
TH2_k127_1725883_11 Tetratricopeptide TPR_2 repeat protein - - - 0.00007036 55.0
TH2_k127_1725883_2 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 345.0
TH2_k127_1725883_3 Elongation factor SelB winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009692 285.0
TH2_k127_1725883_4 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000007599 221.0
TH2_k127_1725883_5 CYTH K05873 - 4.6.1.1 0.000000000000000000000000000005656 126.0
TH2_k127_1725883_6 GYD domain - - - 0.00000000000000000000000000637 124.0
TH2_k127_1725883_7 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000003472 105.0
TH2_k127_1725883_8 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.00000000000003199 79.0
TH2_k127_1725883_9 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000003456 68.0
TH2_k127_1736736_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 523.0
TH2_k127_1736736_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000008763 213.0
TH2_k127_1736736_2 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 0.0000000000000000000000000000000000000000000003007 169.0
TH2_k127_1736736_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000009193 178.0
TH2_k127_1736736_4 - - - - 0.0000000000000002663 87.0
TH2_k127_1736736_5 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.000001043 57.0
TH2_k127_1741970_0 PTS system, fructose subfamily, IIC subunit K02768,K02769,K02770,K11203 - 2.7.1.202 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 365.0
TH2_k127_17664_0 Belongs to the ompA family - - - 0.00000009027 63.0
TH2_k127_17766_0 Protein of unknown function (DUF1329) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 584.0
TH2_k127_17766_1 Protein of unknown function (DUF1302) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 496.0
TH2_k127_17766_2 AcrB/AcrD/AcrF family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 316.0
TH2_k127_17766_3 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 292.0
TH2_k127_185434_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 368.0
TH2_k127_185434_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000001082 216.0
TH2_k127_185434_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000001314 182.0
TH2_k127_1862203_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 1.737e-199 630.0
TH2_k127_1862203_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 296.0
TH2_k127_1862203_10 Ribosomal protein L36 K02919 - - 0.0000000000006092 69.0
TH2_k127_1862203_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 302.0
TH2_k127_1862203_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002391 281.0
TH2_k127_1862203_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000008834 217.0
TH2_k127_1862203_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000002905 184.0
TH2_k127_1862203_6 Ribosomal protein L15 K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000001547 175.0
TH2_k127_1862203_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000001911 167.0
TH2_k127_1862203_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000000000000007204 130.0
TH2_k127_1862203_9 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000001281 85.0
TH2_k127_1877632_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004044 285.0
TH2_k127_1877632_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000003164 223.0
TH2_k127_1881112_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 606.0
TH2_k127_1881112_1 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000001391 152.0
TH2_k127_1881112_2 elongation factor SelB, winged helix K03833 - - 0.000000000001497 76.0
TH2_k127_1881112_3 - - - - 0.000000002496 70.0
TH2_k127_1881112_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000005367 48.0
TH2_k127_1897469_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 326.0
TH2_k127_1897469_1 Mur ligase, middle domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000001397 150.0
TH2_k127_1897469_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000001078 80.0
TH2_k127_1897469_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000002535 62.0
TH2_k127_1936946_0 Alpha-2-Macroglobulin K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000001858 259.0
TH2_k127_194072_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009284 274.0
TH2_k127_194072_1 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000003632 211.0
TH2_k127_194072_2 - K01992,K19341 - - 0.00003848 52.0
TH2_k127_194072_3 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0004005 46.0
TH2_k127_1946810_0 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 436.0
TH2_k127_1946810_1 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000008143 156.0
TH2_k127_1970595_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 558.0
TH2_k127_1970595_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000002225 241.0
TH2_k127_1970595_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000001646 223.0
TH2_k127_1970595_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000005275 62.0
TH2_k127_1970595_4 Bacterial alpha-L-rhamnosidase C-terminal domain - - - 0.000159 54.0
TH2_k127_1974713_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 597.0
TH2_k127_1974713_1 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000008993 90.0
TH2_k127_2026277_0 Phosphate transport system permease protein K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 400.0
TH2_k127_2026277_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 325.0
TH2_k127_2026277_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002159 295.0
TH2_k127_2026277_3 Ribosomal protein S1 K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000169 263.0
TH2_k127_2026277_4 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000004489 242.0
TH2_k127_2026277_5 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000006292 219.0
TH2_k127_2026277_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000871 199.0
TH2_k127_2026277_7 PFAM response regulator receiver K07657 - - 0.00000000000000000000000000000000000000000000002405 189.0
TH2_k127_203466_0 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 587.0
TH2_k127_203466_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 388.0
TH2_k127_203466_2 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000001288 116.0
TH2_k127_203466_3 Participates in both transcription termination and antitermination K02600 - - 0.000000001215 66.0
TH2_k127_2061662_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 296.0
TH2_k127_2061662_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000005235 168.0
TH2_k127_2061662_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000001046 139.0
TH2_k127_2061662_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000002376 137.0
TH2_k127_208130_0 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 411.0
TH2_k127_208130_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000005347 129.0
TH2_k127_208130_2 peptidase C26 K01658,K07010 - 4.1.3.27 0.000000000000000000000003268 110.0
TH2_k127_2094673_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 314.0
TH2_k127_2094673_1 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000008306 259.0
TH2_k127_2094673_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000839 48.0
TH2_k127_2108355_0 PFAM Stage II sporulation protein E (SpoIIE) - - - 0.00000000000000000000000000000000000000000000000000000000007794 224.0
TH2_k127_2108355_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000006382 71.0
TH2_k127_2142011_0 Belongs to the arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 439.0
TH2_k127_2142011_1 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000002912 211.0
TH2_k127_2142011_2 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.000001181 59.0
TH2_k127_2183277_0 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 438.0
TH2_k127_2183277_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 434.0
TH2_k127_2183277_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 417.0
TH2_k127_2183277_3 sulfate ABC transporter K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 335.0
TH2_k127_2183277_4 sulfate transport system, permease K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 314.0
TH2_k127_2183277_5 Binds the 23S rRNA K02909 - - 0.000000000000000000000003807 107.0
TH2_k127_2183277_6 Transcriptional regulator - - - 0.000000001132 60.0
TH2_k127_2192015_0 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000004174 235.0
TH2_k127_2192015_1 copper ion binding K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 - 0.000000000000000004175 93.0
TH2_k127_2192015_2 Domain of unknown function (DUF4388) - - - 0.000000000000002779 85.0
TH2_k127_2192015_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000002182 76.0
TH2_k127_2192015_4 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00004772 56.0
TH2_k127_2204733_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 504.0
TH2_k127_2204733_1 surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000003644 269.0
TH2_k127_2204733_2 PFAM thioesterase superfamily protein - - - 0.00000000000000000000002782 105.0
TH2_k127_2204733_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000006269 88.0
TH2_k127_2204733_4 - - - - 0.00000001648 68.0
TH2_k127_2204733_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0004837 51.0
TH2_k127_2232999_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 423.0
TH2_k127_2232999_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 396.0
TH2_k127_2232999_2 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000005615 157.0
TH2_k127_2232999_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000002817 92.0
TH2_k127_2232999_4 transcriptional regulator K05501 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000627 65.0
TH2_k127_2232999_5 - - - - 0.000006938 59.0
TH2_k127_2249963_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 302.0
TH2_k127_2249963_1 sequence-specific DNA binding - - - 0.00000000000008934 74.0
TH2_k127_2259219_0 Domain of unknown function (DUF2437) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001137 271.0
TH2_k127_2259219_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000004679 261.0
TH2_k127_2259219_2 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000003025 222.0
TH2_k127_2259219_3 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000003505 211.0
TH2_k127_2259219_4 VIT family - - - 0.000000000000000000000000000000000000000000000000000000001117 211.0
TH2_k127_2259219_5 - - - - 0.000000000000000000000000000000000000007709 158.0
TH2_k127_2259219_6 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000001597 154.0
TH2_k127_2259219_7 - - - - 0.00000000000000000000234 108.0
TH2_k127_2259219_8 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000005093 62.0
TH2_k127_2265913_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1176.0
TH2_k127_2265913_1 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 339.0
TH2_k127_2265913_2 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 305.0
TH2_k127_2265913_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000002488 218.0
TH2_k127_2265913_4 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000008577 149.0
TH2_k127_2265913_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000002574 97.0
TH2_k127_2265913_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000002177 85.0
TH2_k127_2265913_7 TIGRFAM redox-active disulfide protein 2 - - - 0.000000000003997 70.0
TH2_k127_2292946_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000544 211.0
TH2_k127_2292946_1 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000000001665 162.0
TH2_k127_2292946_2 - - - - 0.00000001641 62.0
TH2_k127_2315604_0 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 394.0
TH2_k127_2315604_1 magnesium chelatase K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 373.0
TH2_k127_2315604_2 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000002111 175.0
TH2_k127_2315604_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000002274 156.0
TH2_k127_2315604_4 Phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000001207 132.0
TH2_k127_232608_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.232e-196 621.0
TH2_k127_232608_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 484.0
TH2_k127_232608_2 Ferrous iron transport protein B K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000002857 154.0
TH2_k127_232608_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000007938 142.0
TH2_k127_2347554_0 pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 308.0
TH2_k127_2347554_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000001771 143.0
TH2_k127_2347554_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000002306 89.0
TH2_k127_2349118_0 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000297 289.0
TH2_k127_2349118_1 nuclear chromosome segregation - - - 0.00000000003119 71.0
TH2_k127_2365016_0 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 438.0
TH2_k127_2365016_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 422.0
TH2_k127_2365016_2 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002799 271.0
TH2_k127_2365016_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000005089 242.0
TH2_k127_2365016_4 Fatty acid desaturase - - - 0.000000000001636 79.0
TH2_k127_2365016_5 Involved in formation and maintenance of cell shape K03570 - - 0.00000009628 63.0
TH2_k127_2373845_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 509.0
TH2_k127_2373845_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000004574 209.0
TH2_k127_2373845_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000005898 139.0
TH2_k127_2373845_3 3-dehydroquinate synthase K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000005333 116.0
TH2_k127_2373845_4 Roadblock/LC7 domain - - - 0.0001966 52.0
TH2_k127_2387249_0 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 303.0
TH2_k127_2387249_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001854 234.0
TH2_k127_2387249_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000003299 214.0
TH2_k127_2387249_3 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000004529 143.0
TH2_k127_2387249_4 Transglycosylase SLT domain - - - 0.000000000000000000000000008112 127.0
TH2_k127_2388322_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 393.0
TH2_k127_2388322_1 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000008749 224.0
TH2_k127_2388322_2 PFAM Peptidase C26 K07010 - - 0.00000000000000005729 84.0
TH2_k127_2391803_0 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 547.0
TH2_k127_2391803_1 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 301.0
TH2_k127_2391803_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000009484 174.0
TH2_k127_2396506_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 289.0
TH2_k127_2396506_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003344 269.0
TH2_k127_2396506_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000214 145.0
TH2_k127_242742_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 314.0
TH2_k127_242742_1 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001114 267.0
TH2_k127_242742_2 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000002503 80.0
TH2_k127_242742_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 0.0004167 46.0
TH2_k127_2433088_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 307.0
TH2_k127_2433088_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000785 85.0
TH2_k127_2433473_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.401e-293 920.0
TH2_k127_2433473_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000003583 206.0
TH2_k127_2433473_2 curli production assembly transport component CsgG - - - 0.000000000000000000000000000008667 137.0
TH2_k127_2454035_0 Tetratricopeptide repeat K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000008481 253.0
TH2_k127_2454035_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000004595 128.0
TH2_k127_2479651_0 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 542.0
TH2_k127_2479651_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000002354 89.0
TH2_k127_2479651_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000291 61.0
TH2_k127_25312_0 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 293.0
TH2_k127_25312_1 - - - - 0.000000000000000000000000000000002113 147.0
TH2_k127_25312_2 - - - - 0.000000000000000000000000003072 117.0
TH2_k127_25312_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000006109 79.0
TH2_k127_2588590_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 324.0
TH2_k127_2588590_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 314.0
TH2_k127_2588590_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000608 271.0
TH2_k127_2588590_3 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000000000002152 186.0
TH2_k127_2588590_4 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000002402 175.0
TH2_k127_2588590_5 Tetratricopeptide repeat - - - 0.0000000000000000008332 96.0
TH2_k127_2588590_6 Roadblock/LC7 domain - - - 0.0000178 55.0
TH2_k127_2592223_0 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 420.0
TH2_k127_2592223_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000006146 126.0
TH2_k127_2613515_0 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000768 145.0
TH2_k127_2613515_1 ECF sigma factor K03088 - - 0.000000000000000001469 94.0
TH2_k127_2613515_2 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000004445 96.0
TH2_k127_2613515_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000009869 70.0
TH2_k127_2651025_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 471.0
TH2_k127_2651025_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 437.0
TH2_k127_2678910_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 381.0
TH2_k127_2678910_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 336.0
TH2_k127_2678910_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000721 275.0
TH2_k127_2678910_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000007661 136.0
TH2_k127_270119_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 364.0
TH2_k127_270119_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 291.0
TH2_k127_270119_2 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000009252 159.0
TH2_k127_270119_3 PFAM von Willebrand factor type A K07114,K12511 - - 0.0000000000000000000001247 110.0
TH2_k127_270119_4 Thioredoxin-like - - - 0.00000000000000000001117 99.0
TH2_k127_270119_5 Outer membrane protein beta-barrel domain - - - 0.00000000001717 76.0
TH2_k127_2706476_0 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 293.0
TH2_k127_2706476_1 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000003481 164.0
TH2_k127_2706476_2 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000007091 147.0
TH2_k127_2706476_3 - - - - 0.00000000000000000000000005533 116.0
TH2_k127_2706476_4 PFAM Phosphoribosyltransferase - - - 0.0000000001514 64.0
TH2_k127_273443_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 459.0
TH2_k127_273443_1 PFAM Aldehyde dehydrogenase - - - 0.00000000000000000000000000000000000002879 153.0
TH2_k127_273443_10 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000828 54.0
TH2_k127_273443_11 Belongs to the P(II) protein family - - - 0.0001663 48.0
TH2_k127_273443_2 PFAM thioesterase superfamily K07107 - - 0.000000000000000000000000000000000004654 141.0
TH2_k127_273443_3 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000002863 133.0
TH2_k127_273443_4 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000005669 128.0
TH2_k127_273443_5 Domain of unknown function DUF302 - - - 0.000000000000000000000000000003149 124.0
TH2_k127_273443_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000001398 103.0
TH2_k127_273443_7 Protein of unknown function (DUF2892) - - - 0.000000000000001199 89.0
TH2_k127_273443_8 COG0848 Biopolymer transport protein K03559 - - 0.00000003705 63.0
TH2_k127_273443_9 Putative regulatory protein - - - 0.00000004477 57.0
TH2_k127_2782218_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 348.0
TH2_k127_2782218_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 326.0
TH2_k127_2782218_2 Beta-eliminating lyase K01667,K01668 - 4.1.99.1,4.1.99.2 0.000009353 48.0
TH2_k127_27859_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.998e-233 735.0
TH2_k127_27859_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 379.0
TH2_k127_27859_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000002087 145.0
TH2_k127_27859_3 KaiC K07331 - - 0.0005123 43.0
TH2_k127_2791980_0 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003056 270.0
TH2_k127_2791980_1 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000004545 124.0
TH2_k127_2791980_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000005921 90.0
TH2_k127_2832442_0 Belongs to the glutamate synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 595.0
TH2_k127_2832442_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 428.0
TH2_k127_2832442_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 354.0
TH2_k127_2832442_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 327.0
TH2_k127_2832442_4 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000005852 228.0
TH2_k127_2832442_5 4 iron, 4 sulfur cluster binding K02573 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000004354 73.0
TH2_k127_28399_0 Cytochrome c554 and c-prime - - - 1.896e-220 691.0
TH2_k127_28399_1 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 512.0
TH2_k127_28399_10 Peptidase family M23 - - - 0.00000000000000000000000000000000000002893 154.0
TH2_k127_28399_11 ACT domain K09707 - - 0.00000000000383 78.0
TH2_k127_28399_2 PFAM Cys Met metabolism K01760,K01761 - 4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 442.0
TH2_k127_28399_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 362.0
TH2_k127_28399_4 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002028 283.0
TH2_k127_28399_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001612 284.0
TH2_k127_28399_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000003141 247.0
TH2_k127_28399_7 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000002116 201.0
TH2_k127_28399_8 DNA photolyase activity - - - 0.0000000000000000000000000000000000000000000002266 173.0
TH2_k127_28399_9 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000186 176.0
TH2_k127_2881357_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 389.0
TH2_k127_2881357_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 291.0
TH2_k127_2881357_10 Phosphotransferase K07102 - 2.7.1.221 0.0000000000000000000001945 109.0
TH2_k127_2881357_11 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000037 91.0
TH2_k127_2881357_12 PFAM Serine threonine-protein kinase-like domain K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000002656 80.0
TH2_k127_2881357_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116 - - 0.0000000000061 68.0
TH2_k127_2881357_14 Bacterial regulatory protein, Fis family K10126,K17061 - - 0.00004024 51.0
TH2_k127_2881357_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004481 288.0
TH2_k127_2881357_3 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004552 275.0
TH2_k127_2881357_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000001833 255.0
TH2_k127_2881357_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000123 236.0
TH2_k127_2881357_6 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000003057 172.0
TH2_k127_2881357_7 positive regulation of growth rate - - - 0.000000000000000000000000000000000003928 151.0
TH2_k127_2881357_8 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000001806 127.0
TH2_k127_2881357_9 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000002831 137.0
TH2_k127_292907_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 4.382e-222 691.0
TH2_k127_292907_1 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 590.0
TH2_k127_292907_2 ABC transporter K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 380.0
TH2_k127_292907_3 ABC-2 family transporter protein K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 320.0
TH2_k127_292907_4 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006489 267.0
TH2_k127_292907_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000413 244.0
TH2_k127_292907_6 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000000001259 158.0
TH2_k127_2930461_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 347.0
TH2_k127_2930461_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000374 198.0
TH2_k127_2930461_2 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000002299 166.0
TH2_k127_2930461_3 Pfam AhpC TSA family - - - 0.000000000000000000000000001519 121.0
TH2_k127_2930461_4 signal peptide peptidase SppA, 67K type K04773,K04774 - - 0.00000000000000000000002757 106.0
TH2_k127_2930461_5 TIGRFAM phosphoesterase, MJ0936 family K01090 - 3.1.3.16 0.0000001961 62.0
TH2_k127_2943701_0 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 350.0
TH2_k127_2943701_1 oxidase subunit - - - 0.0000000000001817 79.0
TH2_k127_302421_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K09384 - - 0.000000000000000000000000000000000000227 154.0
TH2_k127_302421_1 Hsp70 protein - - - 0.0000000000000000000000000000002065 136.0
TH2_k127_3040595_0 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 462.0
TH2_k127_3040595_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 328.0
TH2_k127_3040595_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000002777 232.0
TH2_k127_3040595_3 Peptidase family M54 K06974 - - 0.00000002355 62.0
TH2_k127_3054998_0 carboxypeptidase - - - 4.461e-196 642.0
TH2_k127_3054998_1 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 313.0
TH2_k127_3054998_2 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000002469 136.0
TH2_k127_3054998_3 Nitrogen fixation protein NifU - - - 0.0000000000000000005458 93.0
TH2_k127_3054998_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000001102 65.0
TH2_k127_3054998_5 - - - - 0.0000000009644 66.0
TH2_k127_3054998_6 Domain of unknown function (DUF4412) - - - 0.00003067 55.0
TH2_k127_3057349_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000006431 143.0
TH2_k127_3057349_1 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000003532 142.0
TH2_k127_3057349_2 Serine aminopeptidase, S33 - - - 0.00000000001915 74.0
TH2_k127_3067816_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 596.0
TH2_k127_3067816_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 486.0
TH2_k127_3067816_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002301 255.0
TH2_k127_3067816_3 Preprotein translocase subunit K03210 - - 0.00000000000000000005263 95.0
TH2_k127_3067816_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000002038 59.0
TH2_k127_3076378_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 8.758e-277 862.0
TH2_k127_3076378_1 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000000000000000000000002978 190.0
TH2_k127_3076378_2 Vitamin K epoxide reductase family - - - 0.00000000000000000000000000000001662 143.0
TH2_k127_3076378_3 Polysulphide reductase, NrfD - - - 0.0000000000003999 70.0
TH2_k127_309249_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.683e-195 616.0
TH2_k127_309249_1 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000003703 231.0
TH2_k127_309249_2 GAF domain K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000000001433 184.0
TH2_k127_309728_0 4Fe-4S dicluster domain - - - 7.651e-197 639.0
TH2_k127_309728_1 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.0000000000000000000000000000000000000000000001014 172.0
TH2_k127_309728_2 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000002498 169.0
TH2_k127_309728_3 protein conserved in bacteria K09931 - - 0.000000000000008867 78.0
TH2_k127_3127687_0 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000000000000006562 196.0
TH2_k127_3127687_1 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000000000000000004659 126.0
TH2_k127_31315_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 436.0
TH2_k127_31315_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 417.0
TH2_k127_31315_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000002412 234.0
TH2_k127_31315_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000361 231.0
TH2_k127_31315_4 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000002373 187.0
TH2_k127_31315_5 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.0000000000000003145 89.0
TH2_k127_31315_6 Pfam Anion-transporting ATPase - - - 0.0000000000000256 74.0
TH2_k127_3160400_0 K transport systems K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005258 266.0
TH2_k127_3160400_1 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000002449 190.0
TH2_k127_3207212_0 nucleotidase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 304.0
TH2_k127_3207212_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000001357 235.0
TH2_k127_3207212_2 response regulator receiver - - - 0.0000000000000000000000000000000001994 137.0
TH2_k127_3207212_3 - - - - 0.00000000000000000000000000001693 122.0
TH2_k127_323966_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 1.561e-251 805.0
TH2_k127_3264455_0 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000001612 264.0
TH2_k127_3264455_1 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001099 267.0
TH2_k127_3264455_2 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000000000000000000000000000009921 222.0
TH2_k127_3264455_3 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000006201 157.0
TH2_k127_3264455_4 YhhN family - - - 0.000000000000000000000006276 110.0
TH2_k127_3264455_6 Pfam:TPM K08988 - - 0.000001142 56.0
TH2_k127_3289250_0 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000001607 241.0
TH2_k127_3289250_1 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000000803 143.0
TH2_k127_3289250_2 TonB C terminal K03646,K03832 - - 0.000000000005037 70.0
TH2_k127_3336208_0 Phosphomethylpyrimidine kinase K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000002366 207.0
TH2_k127_3336208_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000009148 198.0
TH2_k127_3336208_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000006685 107.0
TH2_k127_3358134_0 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.0000000000000000000000000000000000002256 151.0
TH2_k127_3358134_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000006819 96.0
TH2_k127_3358134_2 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000001243 90.0
TH2_k127_3358134_3 - - - - 0.00000000001989 65.0
TH2_k127_3369991_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.071e-271 859.0
TH2_k127_3369991_1 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 291.0
TH2_k127_3369991_2 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 296.0
TH2_k127_3369991_3 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000004561 264.0
TH2_k127_3369991_4 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000005768 183.0
TH2_k127_3369991_5 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000001171 150.0
TH2_k127_3369991_6 Universal stress protein - - - 0.0000000000000000000000000000002598 134.0
TH2_k127_3369991_7 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000001588 128.0
TH2_k127_3369991_8 Tetratricopeptide repeat - - - 0.000000000005238 79.0
TH2_k127_3369991_9 Domain of unknown function (DUF1844) - - - 0.000009408 54.0
TH2_k127_3381280_0 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000114 195.0
TH2_k127_3406460_0 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 353.0
TH2_k127_3406460_1 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000000000000000001088 176.0
TH2_k127_3415043_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000001087 156.0
TH2_k127_3415043_1 Domain of unknown function (DUF4880) K07165 - - 0.000004009 57.0
TH2_k127_3420081_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 7.165e-214 679.0
TH2_k127_3420081_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000002589 87.0
TH2_k127_3420081_2 Outer membrane protein (OmpH-like) K06142 - - 0.000000008589 67.0
TH2_k127_3424215_0 coagulation factor 5 8 type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 522.0
TH2_k127_3424215_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000007033 141.0
TH2_k127_3458491_0 aconitate hydratase K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 486.0
TH2_k127_3458491_1 PFAM CBS domain containing protein K07168 - - 0.0000000000000000000000000000000000001179 147.0
TH2_k127_3458491_2 Putative adhesin - - - 0.000000323 62.0
TH2_k127_3460443_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 601.0
TH2_k127_3460443_1 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 488.0
TH2_k127_3460443_2 - - - - 0.0003772 49.0
TH2_k127_3466756_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 494.0
TH2_k127_3466756_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 478.0
TH2_k127_3469713_0 FMN binding - - - 8.35e-239 750.0
TH2_k127_3469713_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K18331 - 1.12.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 533.0
TH2_k127_3469713_2 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001303 276.0
TH2_k127_3469713_3 lactate/malate dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000009497 172.0
TH2_k127_3473926_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.758e-287 913.0
TH2_k127_3473926_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000008141 193.0
TH2_k127_3473926_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000002355 94.0
TH2_k127_3473926_3 PFAM type II secretion system protein E K02283 - - 0.000000002177 59.0
TH2_k127_3473926_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000002371 66.0
TH2_k127_3473926_5 Histone deacetylase domain K04768 - - 0.0001291 46.0
TH2_k127_3477434_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 4.911e-219 689.0
TH2_k127_3477434_1 component II K01658,K01664 GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.00000000000000000000000000001412 124.0
TH2_k127_3482554_0 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 466.0
TH2_k127_3482554_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 401.0
TH2_k127_3482554_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 351.0
TH2_k127_3482554_3 - - - - 0.00000000000000000000000000000000000000008173 151.0
TH2_k127_3482554_4 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000000000000000000000000000006005 153.0
TH2_k127_3482554_5 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000004263 146.0
TH2_k127_3482554_6 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.0000000000000000000000000000000004485 146.0
TH2_k127_3482554_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000004862 133.0
TH2_k127_3482554_8 Biotin-lipoyl like K01993 - - 0.0003919 51.0
TH2_k127_3514044_0 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000001116 103.0
TH2_k127_3514044_1 Crp-like helix-turn-helix domain K10914 - - 0.0000000002324 71.0
TH2_k127_3514044_2 CAAX protease self-immunity K07052 - - 0.0000000002777 71.0
TH2_k127_3516794_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 360.0
TH2_k127_3516794_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000009308 76.0
TH2_k127_3544518_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 629.0
TH2_k127_3544518_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 298.0
TH2_k127_3544518_2 PFAM Cation transporter K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 311.0
TH2_k127_3544518_3 Protein export membrane protein K07003 - - 0.000000000000000000000000000000002285 142.0
TH2_k127_3544518_4 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000008551 136.0
TH2_k127_3544518_5 - - - - 0.00000000000000009887 91.0
TH2_k127_3586320_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 624.0
TH2_k127_3586320_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 340.0
TH2_k127_3586320_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000002199 170.0
TH2_k127_3586816_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 302.0
TH2_k127_3586816_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000001127 157.0
TH2_k127_3591869_0 Bacterial sugar transferase K03606 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 392.0
TH2_k127_3591869_1 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003414 291.0
TH2_k127_3591869_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000001494 212.0
TH2_k127_3591869_3 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.000000000000000000000000000000000000000000001266 175.0
TH2_k127_3591869_4 SnoaL-like domain - - - 0.0000000000000556 80.0
TH2_k127_3592996_0 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 569.0
TH2_k127_3592996_1 Permease, YjgP YjgQ - - - 0.000000000000000000000000000000000000000000000000000002881 205.0
TH2_k127_3592996_2 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000236 138.0
TH2_k127_3592996_3 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000006241 115.0
TH2_k127_3604931_0 Phospholipase B - - - 0.0 1131.0
TH2_k127_3604931_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 589.0
TH2_k127_3604931_2 Pfam Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 362.0
TH2_k127_3605392_0 Dehydrogenase E1 component K00164,K01616 - 1.2.4.2,4.1.1.71 2.197e-202 646.0
TH2_k127_362075_0 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 393.0
TH2_k127_362075_1 DAK2 domain fusion protein YloV K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 372.0
TH2_k127_362075_2 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000001283 243.0
TH2_k127_362075_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000004426 161.0
TH2_k127_362075_4 Protein of unknown function (DUF2892) - - - 0.0000000000000000001713 92.0
TH2_k127_3625087_0 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000003294 175.0
TH2_k127_3625087_1 Porin subfamily - - - 0.00000000000000000000000000000000000000000000003688 188.0
TH2_k127_3625087_2 - - - - 0.0000000000000000000000000000000000000287 154.0
TH2_k127_3625087_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000004429 83.0
TH2_k127_3663361_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.774e-296 919.0
TH2_k127_3663361_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000001319 87.0
TH2_k127_3663361_2 belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0001348 45.0
TH2_k127_3665803_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 322.0
TH2_k127_3665803_1 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 308.0
TH2_k127_3665803_2 ABC-2 family transporter protein - - - 0.00000000000000003155 89.0
TH2_k127_3665803_3 PFAM Outer membrane efflux protein K03287 - - 0.0007132 48.0
TH2_k127_3677872_0 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000001286 243.0
TH2_k127_3677872_1 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000005288 162.0
TH2_k127_3677872_2 PFAM cytochrome c - - - 0.00000000000000000000000000009019 117.0
TH2_k127_369486_0 Mechanosensitive ion channel K16052,K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 340.0
TH2_k127_369486_1 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000000000000000000000000000000009432 223.0
TH2_k127_369486_2 Pfam:TPM K08988 - - 0.0000000000000000000000000005556 117.0
TH2_k127_3710310_0 SMART serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 575.0
TH2_k127_3710310_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 425.0
TH2_k127_3710310_2 Forkhead associated domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001603 274.0
TH2_k127_3710310_3 cheY-homologous receiver domain - - - 0.00007066 46.0
TH2_k127_3713950_0 ABC transporter transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 399.0
TH2_k127_3713950_1 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 304.0
TH2_k127_3713950_2 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000006856 198.0
TH2_k127_3713950_3 protein conserved in bacteria K09778 - - 0.000000000000000000000000003456 118.0
TH2_k127_3717105_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 382.0
TH2_k127_3717105_1 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 326.0
TH2_k127_3717105_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000006907 114.0
TH2_k127_3717105_3 PAP2 superfamily - - - 0.000000000000000000000001631 115.0
TH2_k127_3721306_0 FAD dependent oxidoreductase - - - 1.711e-208 661.0
TH2_k127_3721306_1 Pyridine nucleotide-disulphide oxidoreductase K03885,K10716 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 558.0
TH2_k127_3721306_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 484.0
TH2_k127_3721306_3 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001125 278.0
TH2_k127_3742296_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000002429 214.0
TH2_k127_3742296_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000004452 215.0
TH2_k127_3742296_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000003576 182.0
TH2_k127_3742296_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0001185 49.0
TH2_k127_3757503_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 342.0
TH2_k127_3757503_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000003483 260.0
TH2_k127_3757503_2 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000003266 253.0
TH2_k127_3757503_3 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000592 214.0
TH2_k127_3757503_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000001838 193.0
TH2_k127_3757503_5 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000002695 175.0
TH2_k127_3757503_6 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000001506 135.0
TH2_k127_3766728_0 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001234 275.0
TH2_k127_3766728_1 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000000000000000000000000000000000000008961 256.0
TH2_k127_3766728_2 UPF0761 membrane protein K07058 - - 0.000000000000000000728 99.0
TH2_k127_3776277_0 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 510.0
TH2_k127_3776277_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 293.0
TH2_k127_3776277_2 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000007126 119.0
TH2_k127_380595_0 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 343.0
TH2_k127_380595_1 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006342 284.0
TH2_k127_380595_2 cell redox homeostasis - - - 0.00000000000000000000000000000000001229 143.0
TH2_k127_3849317_0 B12 binding domain K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 491.0
TH2_k127_3849317_1 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009773 429.0
TH2_k127_3849317_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 329.0
TH2_k127_3849317_3 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000004472 210.0
TH2_k127_3849317_4 CHASE - - - 0.0000000000000000000000000006355 132.0
TH2_k127_3905739_0 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001752 271.0
TH2_k127_3905739_1 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000006044 200.0
TH2_k127_3905739_2 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000000000158 150.0
TH2_k127_3905739_3 stage 0 sporulation protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000309 150.0
TH2_k127_3905739_4 EamA-like transporter family - - - 0.0000000000000000000000000000004545 134.0
TH2_k127_3905739_5 Hfq protein - - - 0.000000000000000000000000002316 115.0
TH2_k127_3918881_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 350.0
TH2_k127_3918881_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001561 229.0
TH2_k127_3918881_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000008695 101.0
TH2_k127_392590_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 417.0
TH2_k127_392590_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000001469 224.0
TH2_k127_392590_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000004571 189.0
TH2_k127_3946103_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.912e-312 976.0
TH2_k127_3946103_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 397.0
TH2_k127_3946103_2 PFAM 2-nitropropane dioxygenase NPD K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 342.0
TH2_k127_3977344_0 mannose metabolic process K01191 - 3.2.1.24 7.43e-210 675.0
TH2_k127_3979389_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000005581 242.0
TH2_k127_3979389_1 response regulator - - - 0.00000000000001022 89.0
TH2_k127_4011038_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 397.0
TH2_k127_4011038_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000001213 121.0
TH2_k127_4011038_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075 - 2.4.2.8,6.3.4.19 0.0000002565 58.0
TH2_k127_4015764_0 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.00000000000000000000000000000000000000000000000000000000002934 216.0
TH2_k127_4015764_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000002651 182.0
TH2_k127_4059330_0 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 357.0
TH2_k127_4059330_1 Domain of unknown function (DUF1972) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 328.0
TH2_k127_4059330_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000006027 174.0
TH2_k127_4090060_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000005819 203.0
TH2_k127_410066_0 PFAM Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003384 278.0
TH2_k127_410066_1 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002257 279.0
TH2_k127_410066_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000003202 110.0
TH2_k127_4156797_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 417.0
TH2_k127_4156797_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000166 255.0
TH2_k127_4156797_2 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000016 233.0
TH2_k127_4156797_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000008352 180.0
TH2_k127_4156797_4 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000001707 181.0
TH2_k127_4156797_5 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000001521 161.0
TH2_k127_4156797_6 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000001367 137.0
TH2_k127_4156797_7 Lipoate-protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000005543 130.0
TH2_k127_4156797_8 Sporulation and spore germination - - - 0.0000000003393 72.0
TH2_k127_4158021_0 COG0659 Sulfate permease and related transporters (MFS superfamily K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 395.0
TH2_k127_4158021_1 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 359.0
TH2_k127_4158021_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 291.0
TH2_k127_4158021_3 - - - - 0.000000000000000000000000000000000000002137 152.0
TH2_k127_4218358_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000002069 213.0
TH2_k127_4218358_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000717 173.0
TH2_k127_4218358_2 signal transduction histidine kinase - - - 0.000000000000000000000000000000000009933 151.0
TH2_k127_4218358_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000007066 126.0
TH2_k127_4218358_4 Protein of unknown function (DUF465) - - - 0.0001414 51.0
TH2_k127_4218358_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0003316 52.0
TH2_k127_4224844_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.25e-218 699.0
TH2_k127_4224844_1 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 489.0
TH2_k127_4224844_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0007844 42.0
TH2_k127_4230634_0 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 347.0
TH2_k127_4230634_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000002852 267.0
TH2_k127_4230634_2 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000002968 171.0
TH2_k127_4230634_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000003527 132.0
TH2_k127_4230634_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000009973 105.0
TH2_k127_4230634_5 - - - - 0.0000000157 58.0
TH2_k127_4256764_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 377.0
TH2_k127_4256764_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002689 235.0
TH2_k127_4256764_2 TIGRFAM hydrogenase maturation protease - - - 0.0000000000001185 82.0
TH2_k127_4256764_4 maturation K03605 - - 0.000001799 55.0
TH2_k127_4262660_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 545.0
TH2_k127_4262660_1 Domain of unknown function (DUF4032) - - - 0.000000000000000000000000000000002014 134.0
TH2_k127_430182_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 453.0
TH2_k127_430182_1 response regulator K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 392.0
TH2_k127_4307742_0 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 454.0
TH2_k127_4307742_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 345.0
TH2_k127_4307742_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000005693 228.0
TH2_k127_4307742_3 Essential cell division protein K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.000004003 60.0
TH2_k127_4307742_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0002622 49.0
TH2_k127_4314649_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000001111 234.0
TH2_k127_4314649_1 Chase2 domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000001087 205.0
TH2_k127_4314649_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000002486 93.0
TH2_k127_4320277_0 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 372.0
TH2_k127_4320277_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 339.0
TH2_k127_4396500_0 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 418.0
TH2_k127_4396500_1 YmdB-like protein K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003096 284.0
TH2_k127_4396500_2 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006178 255.0
TH2_k127_4396500_3 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000000001824 184.0
TH2_k127_4396500_4 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.0000000000000000000000000000000004539 141.0
TH2_k127_4396500_5 Glycosyl transferase family 2 K12984 - - 0.000000000000000000004557 107.0
TH2_k127_4419101_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 1.038e-252 792.0
TH2_k127_4419101_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000001682 86.0
TH2_k127_4462219_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1060.0
TH2_k127_4462219_1 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000184 240.0
TH2_k127_453618_0 Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001533 289.0
TH2_k127_453618_1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001457 278.0
TH2_k127_453618_2 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000005596 201.0
TH2_k127_453618_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000059 72.0
TH2_k127_453618_4 Outer membrane protein (OmpH-like) K06142 - - 0.000000002264 66.0
TH2_k127_453618_5 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.0000003951 59.0
TH2_k127_4538711_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 483.0
TH2_k127_4538711_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 407.0
TH2_k127_4538711_2 protein conserved in bacteria K09793 - - 0.00000000000000000000000000000000000000000000000005006 186.0
TH2_k127_4538711_3 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.00000000000000000000000000000000000002779 154.0
TH2_k127_4538711_4 Sodium:solute symporter family K03307 - - 0.00000000000000000000000000000004419 127.0
TH2_k127_456682_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 515.0
TH2_k127_456682_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 407.0
TH2_k127_456682_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 299.0
TH2_k127_456682_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.00000000000000000000001805 118.0
TH2_k127_456682_4 - - - - 0.00000000000000001236 94.0
TH2_k127_4613980_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1026.0
TH2_k127_4615483_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 455.0
TH2_k127_4615483_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 352.0
TH2_k127_4615483_2 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 297.0
TH2_k127_4615483_3 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002739 255.0
TH2_k127_4615483_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001032 258.0
TH2_k127_4615483_5 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000005965 201.0
TH2_k127_4615483_6 cellulose binding - - - 0.0000000001227 70.0
TH2_k127_464333_0 prohibitin homologues K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 387.0
TH2_k127_464333_1 PFAM aminotransferase, class I K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 313.0
TH2_k127_464333_2 phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000641 151.0
TH2_k127_4682142_0 COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 352.0
TH2_k127_4682142_1 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 344.0
TH2_k127_4682142_2 PFAM Phenazine biosynthesis PhzC PhzF protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 338.0
TH2_k127_4682142_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 290.0
TH2_k127_4682142_4 FR47-like protein - - - 0.00000000000000000000000000000000000000000000001535 179.0
TH2_k127_4682142_5 peptidyl-tyrosine sulfation - - - 0.00000000000001208 80.0
TH2_k127_4682142_6 ribonuclease BN K07058 - - 0.00001839 57.0
TH2_k127_4712343_0 Pilus assembly protein, PilO K02664 - - 0.0000000000000000004475 94.0
TH2_k127_4712343_1 PFAM Fimbrial assembly family protein K02663 - - 0.00000000000002078 80.0
TH2_k127_4712343_2 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00008034 55.0
TH2_k127_4712343_3 Pilus assembly protein, PilP K02664,K02665 - - 0.00008742 55.0
TH2_k127_4727358_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 531.0
TH2_k127_4727358_1 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 410.0
TH2_k127_4727358_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000008675 169.0
TH2_k127_475346_0 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000008152 211.0
TH2_k127_475346_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000001471 131.0
TH2_k127_475346_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000001211 60.0
TH2_k127_4761673_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 422.0
TH2_k127_4761673_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000398 288.0
TH2_k127_4761673_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000003865 268.0
TH2_k127_4772243_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 398.0
TH2_k127_4772243_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000009238 217.0
TH2_k127_4772243_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000003308 149.0
TH2_k127_4807410_0 TonB dependent receptor K02014 - - 1.443e-301 941.0
TH2_k127_4807410_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000003489 118.0
TH2_k127_4807410_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000001445 71.0
TH2_k127_4831121_0 galactose-1-phosphate K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 396.0
TH2_k127_4831121_2 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000009973 186.0
TH2_k127_4831121_3 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.000000000000000000000001083 110.0
TH2_k127_4831121_4 antisigma factor binding - - - 0.0001645 52.0
TH2_k127_48475_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000157 267.0
TH2_k127_48475_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002404 265.0
TH2_k127_48475_2 Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers K06955 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000425 242.0
TH2_k127_48475_3 Pirin K06911 - - 0.000000000000000000000000000000000000000000001953 169.0
TH2_k127_48475_4 Protein of unknown function (DUF1232) - - - 0.00000000003478 72.0
TH2_k127_48475_5 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 0.000000001414 67.0
TH2_k127_4860929_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005938 278.0
TH2_k127_4860929_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000001814 224.0
TH2_k127_4860929_2 - - - - 0.00000000000000000000000000000000002716 139.0
TH2_k127_4860929_3 Bacterial membrane protein YfhO - - - 0.000003021 59.0
TH2_k127_4863483_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 6.09e-290 897.0
TH2_k127_4863483_1 Pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 1.031e-241 752.0
TH2_k127_4863483_2 Glycine zipper - - - 0.00000000000000000000000000000000000000000000000002241 190.0
TH2_k127_4863483_3 - - - - 0.000000000000000000000000006658 111.0
TH2_k127_4871222_0 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 321.0
TH2_k127_4871222_1 Bacterial protein of unknown function (DUF883) - - - 0.00004989 52.0
TH2_k127_4871222_2 Putative prokaryotic signal transducing protein - - - 0.0001505 51.0
TH2_k127_4872653_0 TIGRFAM TIGR00266 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 466.0
TH2_k127_4872653_1 Pyridoxal-phosphate dependent enzyme K01751 - 4.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 326.0
TH2_k127_4872653_2 Protein of unknown function (DUF533) - - - 0.00000000000000001548 85.0
TH2_k127_4888866_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 358.0
TH2_k127_4888866_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000005054 251.0
TH2_k127_4888866_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000001874 190.0
TH2_k127_4888866_3 Transcriptional regulator - - - 0.0000000000000000000000004049 106.0
TH2_k127_4888981_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 544.0
TH2_k127_4888981_1 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 474.0
TH2_k127_4888981_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000002015 55.0
TH2_k127_489473_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 511.0
TH2_k127_489473_1 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000004289 111.0
TH2_k127_4926745_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 601.0
TH2_k127_4926745_1 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000008871 64.0
TH2_k127_4979825_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 3.312e-197 624.0
TH2_k127_4981035_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 439.0
TH2_k127_4981035_1 AAA-like domain - - - 0.00000000000001968 78.0
TH2_k127_4981035_2 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000002306 68.0
TH2_k127_4981035_3 Belongs to the UPF0248 family K09715 - - 0.0001269 48.0
TH2_k127_4993425_0 PFAM Type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 534.0
TH2_k127_4993425_1 type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002731 308.0
TH2_k127_4993425_2 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000005278 169.0
TH2_k127_4993425_3 Type II secretion system protein G K02456 - - 0.00000000000000000001897 100.0
TH2_k127_4993425_4 PFAM Fimbrial assembly family protein K02663 - - 0.0000005075 62.0
TH2_k127_4993425_5 Pilus assembly protein, PilO K02664 - - 0.0000512 54.0
TH2_k127_4993425_6 Pilus assembly protein - - - 0.0001202 53.0
TH2_k127_4995378_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000003542 219.0
TH2_k127_4995378_1 Transmembrane secretion effector - - - 0.0000000000000009519 82.0
TH2_k127_4995378_2 Rdx family K07401 - - 0.00000000005706 64.0
TH2_k127_4995378_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000008845 59.0
TH2_k127_5005447_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 581.0
TH2_k127_5005447_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000269 271.0
TH2_k127_5005447_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000009393 194.0
TH2_k127_5005447_3 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000007283 179.0
TH2_k127_5005447_4 - - - - 0.00000000000000000000003038 104.0
TH2_k127_5005447_5 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.000000000000000000003136 106.0
TH2_k127_5005447_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000008693 104.0
TH2_k127_5005447_9 VanZ like family - - - 0.00006391 50.0
TH2_k127_5015300_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 531.0
TH2_k127_5015300_1 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000173 241.0
TH2_k127_5015300_2 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000003301 206.0
TH2_k127_5015300_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000102 152.0
TH2_k127_5021762_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 443.0
TH2_k127_5021762_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 376.0
TH2_k127_5021762_10 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000001016 154.0
TH2_k127_5021762_11 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000000000000001889 165.0
TH2_k127_5021762_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000001106 160.0
TH2_k127_5021762_13 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000003966 144.0
TH2_k127_5021762_14 PTS system fructose IIA component K02793 - 2.7.1.191 0.00000000000000000000000005882 114.0
TH2_k127_5021762_15 Phosphotransferase System K11189 - - 0.000000000000000000000001589 105.0
TH2_k127_5021762_16 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000004241 109.0
TH2_k127_5021762_17 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.000000000000000832 80.0
TH2_k127_5021762_18 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 - 0.00000000003479 70.0
TH2_k127_5021762_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 352.0
TH2_k127_5021762_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 346.0
TH2_k127_5021762_4 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 294.0
TH2_k127_5021762_5 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000498 284.0
TH2_k127_5021762_6 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000004893 227.0
TH2_k127_5021762_7 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000004962 213.0
TH2_k127_5021762_8 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000007705 186.0
TH2_k127_5021762_9 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000001181 181.0
TH2_k127_5059277_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000008576 201.0
TH2_k127_5059277_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.0000000000000000000000000000000000000000000000000002178 199.0
TH2_k127_5059277_2 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519,K18021 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.5.3,1.2.99.8 0.00000000000000000000000000000000000000000006279 182.0
TH2_k127_5059277_3 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000001145 163.0
TH2_k127_5059277_4 Xanthine dehydrogenase - - - 0.0001609 47.0
TH2_k127_5089767_0 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 518.0
TH2_k127_5089767_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 444.0
TH2_k127_5089767_2 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 383.0
TH2_k127_5089767_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 304.0
TH2_k127_5089767_4 Vitamin K epoxide reductase family - - - 0.00000000000000000000000000004137 134.0
TH2_k127_5105168_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 496.0
TH2_k127_5105168_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 301.0
TH2_k127_5105168_2 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000005815 137.0
TH2_k127_51162_0 PFAM Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 502.0
TH2_k127_51162_1 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 306.0
TH2_k127_51162_2 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 299.0
TH2_k127_5132574_0 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000002339 198.0
TH2_k127_5132574_1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000002533 199.0
TH2_k127_5132574_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000003242 129.0
TH2_k127_5132574_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000103 79.0
TH2_k127_5143735_0 cellulose binding - - - 4.824e-317 996.0
TH2_k127_5143735_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 404.0
TH2_k127_5143735_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01459,K01501,K11206,K13566 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0030312,GO:0044464,GO:0050152,GO:0071944,GO:0106008 3.5.1.3,3.5.1.77,3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 306.0
TH2_k127_5143735_3 FAD binding domain - - - 0.000000000000000000000000000000000000008778 157.0
TH2_k127_5143735_4 COG1629 Outer membrane receptor proteins, mostly Fe transport K16087 - - 0.0000000000000000000000000000002109 143.0
TH2_k127_5160605_0 PDZ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 446.0
TH2_k127_5239739_0 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 546.0
TH2_k127_5239739_1 Protein of unknown function (DUF1232) - - - 0.000000000000000002941 90.0
TH2_k127_5257834_0 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000002739 183.0
TH2_k127_5257834_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000005117 164.0
TH2_k127_5257834_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000004953 140.0
TH2_k127_5257834_3 Belongs to the pseudouridine synthase RsuA family K06178,K06182,K06183 - 5.4.99.19,5.4.99.21,5.4.99.22 0.0000000000000000000000004058 108.0
TH2_k127_5257834_4 Transposase IS200 like - - - 0.000000000000000000000246 102.0
TH2_k127_5265741_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 342.0
TH2_k127_5265741_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 317.0
TH2_k127_5265741_2 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008952 282.0
TH2_k127_5265741_3 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000001705 123.0
TH2_k127_5304948_0 Pfam Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 611.0
TH2_k127_5304948_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 518.0
TH2_k127_5304948_10 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000503 75.0
TH2_k127_5304948_2 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006715 286.0
TH2_k127_5304948_3 Binding-protein-dependent transport system inner membrane component K02050,K15599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001922 279.0
TH2_k127_5304948_4 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005785 286.0
TH2_k127_5304948_5 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000001562 220.0
TH2_k127_5304948_6 Short-chain Dehydrogenase reductase - - - 0.00000000000000000000000000000000000000000000000000000001394 210.0
TH2_k127_5304948_8 Winged helix DNA-binding domain - - - 0.0000000000000000000000000001773 129.0
TH2_k127_5304948_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000004545 90.0
TH2_k127_5375900_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000008133 130.0
TH2_k127_5388649_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 359.0
TH2_k127_5388649_1 response regulator receiver K02481,K07712 - - 0.0000000000000000000000000000000000000000000000000003119 200.0
TH2_k127_5388649_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K01488 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 0.0000000000000000000000000000000000000001133 159.0
TH2_k127_5388649_3 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000009439 108.0
TH2_k127_5388649_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000006948 110.0
TH2_k127_5388649_5 Ribosomal prokaryotic L21 protein K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000001333 105.0
TH2_k127_5388649_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000002146 97.0
TH2_k127_5388649_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000004968 106.0
TH2_k127_5402949_0 PFAM ABC transporter K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 322.0
TH2_k127_5402949_1 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000094 287.0
TH2_k127_5402949_2 hydroxypyruvate reductase K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000003728 174.0
TH2_k127_5402949_3 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000001538 168.0
TH2_k127_5402949_4 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000001036 155.0
TH2_k127_5402949_5 Receptor family ligand binding region K01999 - - 0.00000000000000000000000007399 122.0
TH2_k127_5402949_6 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.0000000000009555 81.0
TH2_k127_5402949_7 Bacterial membrane protein YfhO - - - 0.00000002879 63.0
TH2_k127_553427_0 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.000000000000000000000000000000000000000000000006141 181.0
TH2_k127_553427_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000158 156.0
TH2_k127_553427_2 growth of symbiont in host cell K07003 - - 0.000000000000000000000007057 118.0
TH2_k127_5561756_0 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 543.0
TH2_k127_5561756_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 379.0
TH2_k127_5561756_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 351.0
TH2_k127_5561756_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000003054 247.0
TH2_k127_5561756_4 - - - - 0.00002085 49.0
TH2_k127_5593244_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000008139 262.0
TH2_k127_5593244_1 Radical SAM superfamily - - - 0.00000000000000000000000000000000000004088 158.0
TH2_k127_5613615_0 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000001564 117.0
TH2_k127_5613615_1 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.000000000000000000000003781 108.0
TH2_k127_5613615_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000001493 117.0
TH2_k127_5613615_3 General secretory system II, protein E domain protein K02652 - - 0.000000000000000437 91.0
TH2_k127_5613615_4 PFAM Peptidase M22, glycoprotease - - - 0.000000002033 66.0
TH2_k127_5648322_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 492.0
TH2_k127_5648322_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001087 258.0
TH2_k127_5648322_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000003123 217.0
TH2_k127_5648322_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.000000000000000000000000000000000000000000000000009031 207.0
TH2_k127_5648322_4 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000004645 184.0
TH2_k127_5648322_5 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000002156 166.0
TH2_k127_5652217_0 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 469.0
TH2_k127_5652217_1 Transglycosylase K05367 - 2.4.1.129 0.00000000000000000000000000000000000007761 153.0
TH2_k127_5668579_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 344.0
TH2_k127_5668579_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001977 259.0
TH2_k127_5668579_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000001233 205.0
TH2_k127_5668579_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000004471 184.0
TH2_k127_5668579_4 Iron-sulfur cluster assembly protein - - - 0.000000000000000000003039 98.0
TH2_k127_5668579_5 DSBA-like thioredoxin domain - - - 0.000000000000000001449 98.0
TH2_k127_5668579_6 YbbR-like protein - - - 0.000003555 59.0
TH2_k127_5668579_7 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0002198 49.0
TH2_k127_5686485_0 Tricorn protease homolog K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 391.0
TH2_k127_5713712_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000005547 155.0
TH2_k127_5713712_1 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000007806 152.0
TH2_k127_5713712_2 SMART protein phosphatase 2C domain protein - - - 0.00000000000000000000000000000174 128.0
TH2_k127_5713712_3 oxidoreductase activity - - - 0.000003459 59.0
TH2_k127_5715671_0 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine - - - 0.0000000000000000000000000000000000000000008043 169.0
TH2_k127_5715671_1 Phosphate acyltransferases K00631 - 2.3.1.15 0.00000000000000000000000000000000000195 148.0
TH2_k127_5715671_2 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000003009 118.0
TH2_k127_5715671_3 - - - - 0.000000000000002746 83.0
TH2_k127_5715671_4 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000003078 78.0
TH2_k127_5718081_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 309.0
TH2_k127_5718081_1 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001395 255.0
TH2_k127_5718081_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000006639 257.0
TH2_k127_5718081_3 FabA-like domain K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000008795 171.0
TH2_k127_5718081_4 DUF167 K09131 - - 0.0002248 52.0
TH2_k127_5718394_0 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 449.0
TH2_k127_5718394_1 His Kinase A (phosphoacceptor) domain K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000104 285.0
TH2_k127_5718394_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000008555 259.0
TH2_k127_5718394_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000001542 164.0
TH2_k127_5718394_4 HD domain - - - 0.00000000000000000000000000000000000004997 162.0
TH2_k127_5720094_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 384.0
TH2_k127_5720094_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000001133 174.0
TH2_k127_5720094_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000009294 139.0
TH2_k127_5720094_3 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000002143 131.0
TH2_k127_5720094_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001151 104.0
TH2_k127_5720094_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000002215 104.0
TH2_k127_5720094_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000003679 96.0
TH2_k127_5720094_7 Could be involved in septation K06412 - - 0.000000000000000003253 95.0
TH2_k127_5720094_8 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000007179 88.0
TH2_k127_5720094_9 - - - - 0.00004529 55.0
TH2_k127_5734579_0 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000005222 239.0
TH2_k127_5734579_1 lipase activity K15349 - - 0.0000000000000000000000000000000000000000000000000142 197.0
TH2_k127_5734579_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000001704 188.0
TH2_k127_5734579_3 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000000001097 85.0
TH2_k127_5734579_4 antisigma factor binding - - - 0.000000000000001386 84.0
TH2_k127_5734579_5 Sigma-54 interaction domain protein K02667 - - 0.000000000000001447 81.0
TH2_k127_5741794_0 Fumarase C C-terminus - - - 1.349e-227 717.0
TH2_k127_5741794_1 Predicted Permease Membrane Region - - - 7.154e-210 667.0
TH2_k127_5741794_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 588.0
TH2_k127_5741794_3 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 416.0
TH2_k127_5741794_4 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D K01424,K05597 GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0032787,GO:0034641,GO:0042597,GO:0042802,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1,3.5.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 418.0
TH2_k127_5741794_5 Anaerobic c4-dicarboxylate membrane transporter K07791,K07792 - - 0.0000000000000000000000000000000000000000000005226 171.0
TH2_k127_5752253_0 Glycosyl transferase 4-like K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 388.0
TH2_k127_5752253_1 RDD family - - - 0.00000000000000000000000000000001861 132.0
TH2_k127_5752253_2 deacetylase K01463 - - 0.00004522 49.0
TH2_k127_577092_0 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 526.0
TH2_k127_577092_1 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 404.0
TH2_k127_577092_2 Glycosyl transferase K13693 - 2.4.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 375.0
TH2_k127_577092_3 hydrolase (HAD superfamily) K07026 - 3.1.3.70 0.0000000000000000000000000000000003642 141.0
TH2_k127_577092_4 transmembrane transport - - - 0.00000000000000000000000000000001653 136.0
TH2_k127_577092_5 Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present K03657 - 3.6.4.12 0.0000000000000000000000000009809 119.0
TH2_k127_577092_6 Septum formation initiator K04074 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000002013 63.0
TH2_k127_5770960_0 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000002189 83.0
TH2_k127_5770960_1 nuclear chromosome segregation - - - 0.00000000001255 76.0
TH2_k127_5770960_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000023 51.0
TH2_k127_5813192_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 620.0
TH2_k127_5813192_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001692 254.0
TH2_k127_5813192_2 Putative regulatory protein - - - 0.00000000002077 66.0
TH2_k127_5813192_3 Sh3 type 3 domain protein K01447,K02415,K09774 - 3.5.1.28 0.0004618 50.0
TH2_k127_5822497_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003424 266.0
TH2_k127_5822497_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.0000000000000000000000000000000000000000000000000000000000000000000001633 254.0
TH2_k127_5834896_0 PFAM Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 476.0
TH2_k127_5834896_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 411.0
TH2_k127_5834896_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 347.0
TH2_k127_5834896_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000009965 229.0
TH2_k127_5834896_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000007754 151.0
TH2_k127_5834896_5 - - - - 0.00008252 53.0
TH2_k127_586951_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 473.0
TH2_k127_5872983_0 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 387.0
TH2_k127_5872983_1 PFAM Family of - - - 0.0000000000000000000000000001531 121.0
TH2_k127_5872983_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000212 120.0
TH2_k127_5895050_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 444.0
TH2_k127_5895050_1 pfam nudix K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000001371 175.0
TH2_k127_5921191_0 Methionine biosynthesis protein MetW - - - 0.000000000031 66.0
TH2_k127_5921191_1 PFAM cytochrome c assembly protein K02198 - - 0.0000076 51.0
TH2_k127_5921191_2 to the N-terminal domain of Lon protease K01338,K07157 - 3.4.21.53 0.0000392 53.0
TH2_k127_5957899_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 546.0
TH2_k127_5957899_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 357.0
TH2_k127_5957899_2 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 327.0
TH2_k127_5957899_3 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000001053 152.0
TH2_k127_5957899_4 phosphatase - - - 0.00000000000000000000000000001964 122.0
TH2_k127_5970920_0 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 404.0
TH2_k127_5970920_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.00000000000000000000000001003 116.0
TH2_k127_600833_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 352.0
TH2_k127_600833_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000001202 160.0
TH2_k127_600833_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000008929 53.0
TH2_k127_6025075_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.97e-202 653.0
TH2_k127_6025075_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000785 253.0
TH2_k127_6025075_2 RDD family - - - 0.00000005744 64.0
TH2_k127_6025075_3 transcriptional regulator, SARP family - - - 0.000002364 55.0
TH2_k127_6034085_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1092.0
TH2_k127_6034085_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 2.54e-284 891.0
TH2_k127_6034085_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000001335 161.0
TH2_k127_6034085_3 - - - - 0.00000000000001208 80.0
TH2_k127_6058462_0 Cytochrome c554 and c-prime - - - 1.537e-197 636.0
TH2_k127_6058462_1 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.0000000000000000000000000000000000000000000167 165.0
TH2_k127_6137232_0 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000001138 241.0
TH2_k127_6137232_1 Prokaryotic N-terminal methylation motif - - - 0.000009591 56.0
TH2_k127_6137659_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 504.0
TH2_k127_6137659_1 Chlorophyll synthase, ChlG K04040 - 2.5.1.133,2.5.1.62 0.0000000000004037 81.0
TH2_k127_6139368_0 glycosyltransferase 36 associated - - - 7.053e-228 734.0
TH2_k127_6139368_1 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 318.0
TH2_k127_615553_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.647e-197 656.0
TH2_k127_615553_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000004044 138.0
TH2_k127_6188059_0 Sodium Bile acid symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 441.0
TH2_k127_6188059_1 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002127 280.0
TH2_k127_6188059_2 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000002596 171.0
TH2_k127_6188059_3 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000001785 160.0
TH2_k127_6188059_4 Transcriptional regulator K03892,K21903 - - 0.0000000000000000000000009235 109.0
TH2_k127_6230250_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 9.24e-266 828.0
TH2_k127_6230250_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 415.0
TH2_k127_6230250_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 284.0
TH2_k127_6230250_3 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002583 284.0
TH2_k127_6230250_4 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000003161 181.0
TH2_k127_6230250_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000142 178.0
TH2_k127_6230250_6 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000008634 55.0
TH2_k127_6230250_7 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000225 56.0
TH2_k127_6260874_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 578.0
TH2_k127_6260874_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000006085 204.0
TH2_k127_6316951_0 PFAM Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 541.0
TH2_k127_6316951_1 Protein tyrosine kinase - - - 0.00000000000000000003534 105.0
TH2_k127_6316951_2 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0002285 50.0
TH2_k127_6318429_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 516.0
TH2_k127_6318429_1 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 443.0
TH2_k127_6318429_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 346.0
TH2_k127_6318429_3 peptidase inhibitor activity - - - 0.000000000000001989 91.0
TH2_k127_6318429_4 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000002137 82.0
TH2_k127_6349801_0 Diguanylate cyclase - - - 2.197e-194 636.0
TH2_k127_6349801_1 cellulase activity - - - 0.00003848 52.0
TH2_k127_6349992_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K00207,K00219,K00317,K02293,K10797,K12527,K17723 - 1.3.1.1,1.3.1.2,1.3.1.31,1.3.1.34,1.3.5.5,1.5.8.1,1.5.8.2,1.97.1.9 5.778e-206 662.0
TH2_k127_6349992_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000004502 231.0
TH2_k127_6393532_0 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 464.0
TH2_k127_6393532_1 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 436.0
TH2_k127_6393532_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 349.0
TH2_k127_6393532_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003761 277.0
TH2_k127_6393532_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000001607 177.0
TH2_k127_6393532_5 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000000000000000000007005 148.0
TH2_k127_6393532_6 Rubrerythrin - - - 0.00000000000000000000000003228 116.0
TH2_k127_6403974_0 4Fe-4S dicluster domain K00184 - - 6.486e-209 667.0
TH2_k127_6403974_1 Polysulphide reductase K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 407.0
TH2_k127_6430742_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 320.0
TH2_k127_6430742_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00334,K00335 - 1.6.5.3 0.000000000000001822 79.0
TH2_k127_6501608_0 DEAD DEAH box helicase K03724 - - 1.824e-281 878.0
TH2_k127_6619306_0 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000000000000001184 206.0
TH2_k127_6619306_1 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000005182 177.0
TH2_k127_6619306_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000004528 158.0
TH2_k127_6619306_3 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000271 150.0
TH2_k127_6619306_4 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000005011 132.0
TH2_k127_6619306_5 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000003387 113.0
TH2_k127_6619306_6 Protein of unknown function (DUF2662) - - - 0.000000000002319 78.0
TH2_k127_6619306_7 RDD family - - - 0.00001122 57.0
TH2_k127_6620369_0 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000001704 189.0
TH2_k127_6620369_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000007108 150.0
TH2_k127_6620369_2 response regulator - - - 0.0001185 49.0
TH2_k127_6622125_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 355.0
TH2_k127_6622125_1 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000001171 152.0
TH2_k127_6642072_0 5' nucleotidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 439.0
TH2_k127_6642072_1 Protein of unknown function (DUF401) K09133 - - 0.000000000000000000000000000001285 130.0
TH2_k127_6647910_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 421.0
TH2_k127_6647910_1 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000001085 233.0
TH2_k127_6647910_2 PFAM type II secretion system K02653 - - 0.00000000000000000000000000000000001785 137.0
TH2_k127_6647910_3 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000001415 119.0
TH2_k127_6647910_4 PFAM Nucleotidyl transferase - - - 0.00000001498 66.0
TH2_k127_6672398_0 Ras family - - - 0.000000000000000000000000000000000000000000000000000001113 217.0
TH2_k127_6672398_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000001628 186.0
TH2_k127_6672398_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000009683 143.0
TH2_k127_6672398_3 Response regulator receiver domain - - - 0.0000000000000000000000000000001141 133.0
TH2_k127_6707177_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 3.217e-225 724.0
TH2_k127_6707177_1 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000002129 235.0
TH2_k127_6749890_0 Phosphoribosyl transferase domain - - - 0.0000005072 62.0
TH2_k127_6754580_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 563.0
TH2_k127_6754580_1 Zinc-binding dehydrogenase K12957 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 319.0
TH2_k127_6754580_10 - - - - 0.0000000000000000004289 104.0
TH2_k127_6754580_11 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000004624 81.0
TH2_k127_6754580_12 - - - - 0.000000000005048 73.0
TH2_k127_6754580_13 Hsp20/alpha crystallin family K13993 - - 0.000000004088 63.0
TH2_k127_6754580_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000005561 248.0
TH2_k127_6754580_3 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000003454 226.0
TH2_k127_6754580_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000006349 178.0
TH2_k127_6754580_5 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000008597 173.0
TH2_k127_6754580_6 cell redox homeostasis K02199,K03671 - - 0.000000000000000000000000000000201 131.0
TH2_k127_6754580_7 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000000000000000000000000004383 143.0
TH2_k127_6754580_8 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000000000000002044 124.0
TH2_k127_6754580_9 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000002655 101.0
TH2_k127_6760392_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 415.0
TH2_k127_6760392_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 389.0
TH2_k127_6760392_2 PAS domain containing protein K07315,K07675 - 2.7.13.3,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 338.0
TH2_k127_6763274_0 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 473.0
TH2_k127_6763274_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000683 286.0
TH2_k127_6763274_2 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000004545 109.0
TH2_k127_6763274_3 domain, Protein - - - 0.0000000005444 63.0
TH2_k127_6799931_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000006325 230.0
TH2_k127_6799931_1 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000001884 208.0
TH2_k127_6799931_2 STAS domain K04749 - - 0.000000000000000000000000000000007491 133.0
TH2_k127_6799931_3 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000001349 97.0
TH2_k127_6799931_4 Zn peptidase - - - 0.0000003367 62.0
TH2_k127_6842858_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 409.0
TH2_k127_6842858_1 histone H2A K63-linked ubiquitination K10914 - - 0.000000000000000000000000001182 122.0
TH2_k127_6842858_2 Microcin C7 resistance K01297 - 3.4.17.13 0.00000000000000000000000001857 113.0
TH2_k127_6866858_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 8.195e-230 722.0
TH2_k127_6866858_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 1.46e-200 646.0
TH2_k127_6866858_2 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 318.0
TH2_k127_6866858_3 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001149 296.0
TH2_k127_6866858_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000001985 253.0
TH2_k127_6866858_5 Lysophospholipase L1 and related esterases - - - 0.0000000000000000000000000000000000000000000000000000000000000000001953 242.0
TH2_k127_6866858_6 - - - - 0.0000000000000000000000000000000000000000000000000000002165 202.0
TH2_k127_688935_0 Amidohydrolase family K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000008994 265.0
TH2_k127_688935_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000002647 183.0
TH2_k127_689791_0 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 441.0
TH2_k127_689791_1 radical SAM domain protein K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 325.0
TH2_k127_689791_2 FR47-like protein K18816 - 2.3.1.82 0.0000000000000000000000000000000001391 143.0
TH2_k127_689791_3 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01295 - 3.4.17.11 0.000000000000000000000000000000002238 145.0
TH2_k127_689791_4 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000000000000000127 93.0
TH2_k127_689791_5 Domain of unknown function (DUF4440) - - - 0.0000000000000004536 85.0
TH2_k127_6900122_0 Pfam:Arch_ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000024 287.0
TH2_k127_6900122_1 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000003391 165.0
TH2_k127_6983766_0 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 331.0
TH2_k127_6983766_1 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000003669 175.0
TH2_k127_6983766_2 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000002677 156.0
TH2_k127_6983766_3 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000001071 151.0
TH2_k127_6992331_0 quinone binding K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 364.0
TH2_k127_6992331_1 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000001368 67.0
TH2_k127_6992331_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00123 - 1.17.1.9 0.00000001672 60.0
TH2_k127_7000424_0 Prolyl oligopeptidase K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 548.0
TH2_k127_7000751_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009919 540.0
TH2_k127_7000751_1 Amino-transferase class IV K00826 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0006082,GO:0006464,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018065,GO:0018193,GO:0018205,GO:0018272,GO:0018352,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0036211,GO:0040007,GO:0043094,GO:0043102,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071265,GO:0071267,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 366.0
TH2_k127_7000751_2 NIF3 (NGG1p interacting factor 3) K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000009442 227.0
TH2_k127_7000751_3 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000008297 148.0
TH2_k127_7000751_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000002502 54.0
TH2_k127_7008945_0 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 299.0
TH2_k127_7008945_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000002278 174.0
TH2_k127_7008945_2 Hydrogenase maturation protease K08315 - 3.4.23.51 0.00000000000000000000003541 113.0
TH2_k127_7016081_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 511.0
TH2_k127_7016081_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 475.0
TH2_k127_7016081_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001324 278.0
TH2_k127_7016081_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000001238 96.0
TH2_k127_7016081_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000009927 67.0
TH2_k127_7016081_5 Outer membrane protein beta-barrel domain - - - 0.0000000001614 62.0
TH2_k127_7016081_6 cell shape determination - - - 0.0000001665 58.0
TH2_k127_7016081_7 Putative adhesin - - - 0.0004177 51.0
TH2_k127_7023643_0 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 593.0
TH2_k127_7023643_1 Mate efflux family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 367.0
TH2_k127_7023643_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 361.0
TH2_k127_7023643_3 Outer membrane protein beta-barrel family K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002352 278.0
TH2_k127_7023643_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000004848 106.0
TH2_k127_7023643_6 lyase activity - - - 0.000001625 61.0
TH2_k127_7023643_7 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.0001702 53.0
TH2_k127_7023643_8 Domain of unknown function (DUF4388) - - - 0.0002 53.0
TH2_k127_7032729_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 494.0
TH2_k127_7043190_0 regulation of microtubule-based process K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 490.0
TH2_k127_7043190_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 325.0
TH2_k127_7043190_2 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001425 270.0
TH2_k127_7043190_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000003925 254.0
TH2_k127_7043190_4 protoporphyrinogen oxidase activity K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000004522 98.0
TH2_k127_7043190_5 salt-induced outer membrane protein K07283 - - 0.000000000001493 77.0
TH2_k127_7049865_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 586.0
TH2_k127_7049865_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 474.0
TH2_k127_7049865_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 395.0
TH2_k127_7049865_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000003258 167.0
TH2_k127_7049865_4 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000004513 161.0
TH2_k127_7091734_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 368.0
TH2_k127_7091734_1 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000003328 134.0
TH2_k127_710148_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 310.0
TH2_k127_710148_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000002285 94.0
TH2_k127_710148_2 ABC-2 family transporter protein K01992 - - 0.00001479 50.0
TH2_k127_7107828_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004721,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009987,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 314.0
TH2_k127_7107828_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001166 272.0
TH2_k127_7119579_0 COG0644 Dehydrogenases (flavoproteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002958 266.0
TH2_k127_7119579_1 selenocysteine lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000518 251.0
TH2_k127_7119579_2 ABC transporter, transmembrane K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000817 255.0
TH2_k127_7119579_3 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000008958 244.0
TH2_k127_7120743_0 glucosamine-1-phosphate N-acetyltransferase activity K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000006363 177.0
TH2_k127_7120743_1 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000005284 175.0
TH2_k127_7120743_2 domain, Protein - - - 0.00000000000000000000000000000000000004554 165.0
TH2_k127_7137234_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 481.0
TH2_k127_7137234_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 396.0
TH2_k127_7137234_2 PA domain K14647 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001827 291.0
TH2_k127_7137234_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000009452 192.0
TH2_k127_7146190_0 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000001107 212.0
TH2_k127_7146190_1 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000004787 135.0
TH2_k127_7146190_2 NMT1-like family K02051 - - 0.000000000000000000000000000004472 134.0
TH2_k127_7146190_3 - - - - 0.00000000000000000003651 101.0
TH2_k127_7159049_0 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K00131 - 1.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 591.0
TH2_k127_7159049_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 424.0
TH2_k127_7162113_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 6.021e-266 824.0
TH2_k127_7162113_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 2.91e-227 710.0
TH2_k127_7162113_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 604.0
TH2_k127_7162113_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 331.0
TH2_k127_7162113_4 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004304 266.0
TH2_k127_7174102_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 8.269e-244 767.0
TH2_k127_7174102_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000001067 203.0
TH2_k127_7174102_2 NusB family K03625 - - 0.000000000000000000000000000000006203 134.0
TH2_k127_7174102_3 Bacterial transglutaminase-like N-terminal region - - - 0.000159 53.0
TH2_k127_718179_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 9.641e-291 921.0
TH2_k127_718179_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000001889 113.0
TH2_k127_718179_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0001411 45.0
TH2_k127_7192628_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 350.0
TH2_k127_7192628_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925,K07102 - 2.7.1.221 0.0000000000000000000009955 103.0
TH2_k127_7199200_0 - K07221 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 457.0
TH2_k127_7199200_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000002017 216.0
TH2_k127_7199200_2 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K03796 - - 0.0000000000000000000000000000000000000000000000000000003923 211.0
TH2_k127_7199200_3 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000725 149.0
TH2_k127_7209643_0 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 479.0
TH2_k127_7209643_1 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005569 254.0
TH2_k127_721763_0 serine-type peptidase activity K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 492.0
TH2_k127_721763_1 of the RND superfamily K07003 - - 0.0000000000000000000000000000000000000000000000000001007 211.0
TH2_k127_721763_2 FAD binding domain - - - 0.00000000002255 68.0
TH2_k127_7234231_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204 1.2.4.1 3.916e-221 700.0
TH2_k127_7234231_1 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 614.0
TH2_k127_7234231_2 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 469.0
TH2_k127_7234231_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 376.0
TH2_k127_7234231_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000001747 220.0
TH2_k127_7234231_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000002203 159.0
TH2_k127_7234231_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000001784 141.0
TH2_k127_7286374_0 membrane organization K07277,K09800 - - 0.0000000000000000000000000000000000000000000000000000000000002364 244.0
TH2_k127_7296534_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005558 274.0
TH2_k127_7296534_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000118 246.0
TH2_k127_7296534_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000006456 155.0
TH2_k127_7296534_3 FecR protein - - - 0.0000002135 63.0
TH2_k127_7309842_0 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000005557 205.0
TH2_k127_7309842_1 COG0744 Membrane carboxypeptidase (penicillin-binding protein) K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000008435 201.0
TH2_k127_7309842_2 - - - - 0.000000000000000000000000008488 123.0
TH2_k127_7309842_3 - - - - 0.0000000000000109 79.0
TH2_k127_7309842_4 heat shock protein binding K05516 - - 0.000000000001982 75.0
TH2_k127_7309842_5 Domain of unknown function (DUF4115) - - - 0.00000000005393 74.0
TH2_k127_7324738_0 Polyphosphate kinase middle domain K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 603.0
TH2_k127_7324738_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975,K20427 - 2.7.7.27,2.7.7.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 432.0
TH2_k127_7324738_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 379.0
TH2_k127_7324738_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 372.0
TH2_k127_7324738_4 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000003491 132.0
TH2_k127_7324738_5 Domain of unknown function (DUF1905) - - - 0.00000002436 61.0
TH2_k127_7333054_0 CBS domain containing protein K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 505.0
TH2_k127_7333054_1 Pilus assembly protein, PilP - - - 0.00000000006082 76.0
TH2_k127_7401787_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 494.0
TH2_k127_7401787_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 297.0
TH2_k127_7401787_2 monooxygenase activity - - - 0.0000000000000000000000000000004089 135.0
TH2_k127_7401787_3 - - - - 0.0000000000000000000000000001141 127.0
TH2_k127_7401787_4 Tyrosine phosphatase family - - - 0.000000000000000000000000003293 120.0
TH2_k127_744174_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 339.0
TH2_k127_744174_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000001931 128.0
TH2_k127_7491035_0 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 421.0
TH2_k127_7491035_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K09065 - 2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 331.0
TH2_k127_7491035_2 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004666 271.0
TH2_k127_7491035_3 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000004804 94.0
TH2_k127_7491035_4 threonine synthase activity K01733 - 4.2.3.1 0.000000000000000002261 89.0
TH2_k127_7495545_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 445.0
TH2_k127_7495545_1 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000004897 79.0
TH2_k127_758678_0 Heat shock 70 kDa protein K04043 - - 7.264e-220 701.0
TH2_k127_758678_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 371.0
TH2_k127_758678_2 GTP binding K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001622 281.0
TH2_k127_758678_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000001155 209.0
TH2_k127_758678_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000656 132.0
TH2_k127_758678_5 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000009979 139.0
TH2_k127_758678_6 RNA methyltransferase K09761 - 2.1.1.193 0.0000000000000006411 85.0
TH2_k127_7648277_0 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000003501 274.0
TH2_k127_7648277_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000001218 201.0
TH2_k127_7648277_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000003048 60.0
TH2_k127_76739_0 synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 376.0
TH2_k127_76739_1 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 349.0
TH2_k127_76739_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000001319 282.0
TH2_k127_76739_3 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000007173 248.0
TH2_k127_76739_4 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000107 182.0
TH2_k127_76739_5 Transglutaminase-like superfamily - - - 0.000000000000000000000000007352 128.0
TH2_k127_770460_0 Belongs to the GARS family K01945,K01952,K13713 - 6.3.2.6,6.3.4.13,6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 415.0
TH2_k127_770460_1 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 305.0
TH2_k127_770460_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000004602 156.0
TH2_k127_7769429_0 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000001601 246.0
TH2_k127_7769429_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000004187 209.0
TH2_k127_7769429_2 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000001653 143.0
TH2_k127_7774743_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 5.223e-212 687.0
TH2_k127_7774743_1 phosphate ion binding K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 424.0
TH2_k127_7774743_2 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 413.0
TH2_k127_7774743_3 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.00000000000002105 87.0
TH2_k127_7792558_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 292.0
TH2_k127_7792558_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000002901 198.0
TH2_k127_7792558_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.0000000000000000000000000000008722 124.0
TH2_k127_7828459_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 583.0
TH2_k127_7828459_1 PFAM Peptidase M20 K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 437.0
TH2_k127_7828459_2 HD domain K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000008647 202.0
TH2_k127_7828459_3 PQQ enzyme repeat - - - 0.000000000003381 73.0
TH2_k127_7828459_4 Nucleotide-binding protein containing - - - 0.00000006332 60.0
TH2_k127_7839573_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K04085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 608.0
TH2_k127_7839573_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000002903 222.0
TH2_k127_7841139_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 533.0
TH2_k127_7841139_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 511.0
TH2_k127_7842992_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 454.0
TH2_k127_7842992_1 diguanylate cyclase - - - 0.0000000000000000001353 91.0
TH2_k127_7848623_0 secondary active sulfate transmembrane transporter activity K06901 - - 1.309e-217 692.0
TH2_k127_7848623_1 Zincin-like metallopeptidase - - - 0.000000000000000000000000000001818 125.0
TH2_k127_7848660_0 - - - - 0.00000000000000000000000000000000000000000000000001863 205.0
TH2_k127_7848660_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000001776 181.0
TH2_k127_7848660_2 SpoIVB peptidase S55 - - - 0.00000000000000002074 95.0
TH2_k127_7868876_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 376.0
TH2_k127_7868876_1 PFAM Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000001538 180.0
TH2_k127_7868876_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000002329 74.0
TH2_k127_7878107_0 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 322.0
TH2_k127_7878107_1 Putative adhesin - - - 0.00000000000000000000000000000000000000003375 166.0
TH2_k127_7878107_2 Protein of unknown function, DUF255 - - - 0.000000000000000000000005938 115.0
TH2_k127_7878107_3 peptidase S9 prolyl oligopeptidase active site - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000001089 66.0
TH2_k127_7892696_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 307.0
TH2_k127_7892696_1 curli production assembly transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000003228 197.0
TH2_k127_7896487_0 amino acid K03294 - - 8.257e-235 735.0
TH2_k127_7896487_1 amino acid K03294 - - 3.281e-229 721.0
TH2_k127_7896487_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000003435 249.0
TH2_k127_7896487_3 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000000000000000000000000000000001349 237.0
TH2_k127_7896487_4 aminopeptidase activity K19689 - - 0.00000000000000000000000000000000000000000000000000000000002662 224.0
TH2_k127_7896487_5 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000007036 211.0
TH2_k127_7896487_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000001675 177.0
TH2_k127_7896487_7 pfam abc K01990 - - 0.000000000000000001413 90.0
TH2_k127_7935814_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 315.0
TH2_k127_7935814_1 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005593 280.0
TH2_k127_7935814_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000003636 226.0
TH2_k127_7939186_0 PFAM peptidase T2 asparaginase 2 K01444,K13051 - 3.4.19.5,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 328.0
TH2_k127_7939186_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000002525 227.0
TH2_k127_7964618_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 351.0
TH2_k127_7964618_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 307.0
TH2_k127_7973347_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004721,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009987,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 516.0
TH2_k127_7973347_1 Isocitrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 411.0
TH2_k127_7995209_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000156 162.0
TH2_k127_7995209_1 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000006309 116.0
TH2_k127_7995209_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000001756 109.0
TH2_k127_7997126_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 390.0
TH2_k127_7997126_1 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000007772 233.0
TH2_k127_7997126_2 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000004135 172.0
TH2_k127_7997126_3 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000002042 110.0
TH2_k127_7999396_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 5.554e-257 803.0
TH2_k127_7999396_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 441.0
TH2_k127_7999396_2 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 391.0
TH2_k127_7999396_3 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000004898 241.0
TH2_k127_7999396_4 Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.000000000000000000000000000000000000000000000000003616 190.0
TH2_k127_7999396_5 PFAM Peptidase A31, hydrogen uptake protein K03605 - - 0.0000000000000000001132 96.0
TH2_k127_7999396_6 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000001152 70.0
TH2_k127_8017228_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.703e-312 970.0
TH2_k127_8017228_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 609.0
TH2_k127_8017228_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000006908 233.0
TH2_k127_8017228_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000002229 218.0
TH2_k127_8017228_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000007102 80.0
TH2_k127_8054839_0 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002043 279.0
TH2_k127_8054839_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000001412 64.0
TH2_k127_8065537_0 Belongs to the ClpA ClpB family K03696 - - 9.07e-258 828.0
TH2_k127_8065537_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000002741 243.0
TH2_k127_8065537_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000542 115.0
TH2_k127_8065537_3 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000004659 98.0
TH2_k127_8082833_0 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000001102 214.0
TH2_k127_8082833_1 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000003107 136.0
TH2_k127_8082833_2 Peptidase, M28 - - - 0.00000000000004321 87.0
TH2_k127_8091249_0 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 515.0
TH2_k127_8091249_1 Aldo/keto reductase family K07079 - - 0.000000000000000000000000000009346 138.0
TH2_k127_8091249_2 - - - - 0.000007698 59.0
TH2_k127_8106012_0 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 346.0
TH2_k127_8106012_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000007001 157.0
TH2_k127_8106012_2 Saccharopine dehydrogenase C-terminal domain K14157 GO:0003674,GO:0003824,GO:0004753,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006091,GO:0006520,GO:0006553,GO:0006554,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009067,GO:0009068,GO:0009085,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0019477,GO:0019752,GO:0019878,GO:0022607,GO:0031974,GO:0042737,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046395,GO:0046440,GO:0047130,GO:0047131,GO:0051259,GO:0051262,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.5.1.8,1.5.1.9 0.00005706 49.0
TH2_k127_810644_0 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 299.0
TH2_k127_810644_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000002362 185.0
TH2_k127_810644_2 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000009163 142.0
TH2_k127_810644_3 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000001123 113.0
TH2_k127_810644_4 KR domain - - - 0.000000002518 67.0
TH2_k127_8111593_0 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009472 285.0
TH2_k127_8111593_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000001442 173.0
TH2_k127_8111593_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000007103 166.0
TH2_k127_8111593_3 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000507 153.0
TH2_k127_8111593_4 - - - - 0.0000000000382 71.0
TH2_k127_8118421_0 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 344.0
TH2_k127_8118421_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000001579 81.0
TH2_k127_8123613_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 544.0
TH2_k127_8123613_1 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000000000000000000003465 211.0
TH2_k127_8123613_2 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000003475 223.0
TH2_k127_8123613_3 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0000000000000000000000000000000000000000000000001937 180.0
TH2_k127_8123613_4 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000001109 98.0
TH2_k127_8123613_5 protein kinase activity - - - 0.000000000938 70.0
TH2_k127_8204904_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 327.0
TH2_k127_8204904_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001341 282.0
TH2_k127_8204904_2 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000001374 107.0
TH2_k127_8204904_3 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000001307 90.0
TH2_k127_8210175_0 extracellular solute-binding protein, family 5 K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001239 270.0
TH2_k127_8210175_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000001902 235.0
TH2_k127_8210175_2 PAS domain K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000001743 162.0
TH2_k127_8210175_3 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000002031 142.0
TH2_k127_8210175_4 4Fe-4S single cluster domain of Ferredoxin I - - - 0.000000000000000000000000007244 111.0
TH2_k127_8217029_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 420.0
TH2_k127_8217029_1 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0007477 48.0
TH2_k127_8217980_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 433.0
TH2_k127_8217980_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 302.0
TH2_k127_8217980_2 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 297.0
TH2_k127_8217980_3 domain, Protein - - - 0.000003829 57.0
TH2_k127_8217980_4 Tetratricopeptide TPR_2 repeat protein - - - 0.00005652 55.0
TH2_k127_8257819_0 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000001805 204.0
TH2_k127_8257819_1 type II secretion system protein G K02456 - - 0.0000000000000000004188 89.0
TH2_k127_8257819_2 general secretion pathway protein K02456,K02650 - - 0.00000000000005617 83.0
TH2_k127_8331084_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 413.0
TH2_k127_8331084_1 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 314.0
TH2_k127_8331084_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000008182 191.0
TH2_k127_8336829_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 602.0
TH2_k127_8336829_1 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 291.0
TH2_k127_8336829_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000009548 132.0
TH2_k127_8336829_3 - - - - 0.000000000003551 76.0
TH2_k127_8346778_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 468.0
TH2_k127_8346778_1 PFAM ABC transporter related K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 315.0
TH2_k127_8346778_2 Transcriptional regulator - - - 0.00000000000000000000000003273 116.0
TH2_k127_8357383_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000007752 120.0
TH2_k127_8357383_1 Uncharacterised nucleotidyltransferase - - - 0.0000000000000001909 84.0
TH2_k127_8364967_0 protein kinase activity - - - 0.000000000000000000000000000000917 138.0
TH2_k127_8364967_1 Prolyl oligopeptidase family - - - 0.000000000000000000000000000001541 125.0
TH2_k127_8364967_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000001166 128.0
TH2_k127_8364967_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000003605 83.0
TH2_k127_8364967_4 Belongs to the thiolase family K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034308,GO:0034309,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046165,GO:0046395,GO:0055114,GO:0071270,GO:0071271,GO:0071704,GO:0072329,GO:1901575,GO:1901576,GO:1901615,GO:1901617 2.3.1.9 0.0004395 45.0
TH2_k127_838432_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 505.0
TH2_k127_838432_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 348.0
TH2_k127_838432_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000003248 248.0
TH2_k127_838432_3 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000001242 204.0
TH2_k127_838432_4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000005034 71.0
TH2_k127_8390599_0 Two component regulator propeller K07315,K12132,K13924 - 2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3 1.813e-239 770.0
TH2_k127_8445453_0 Elongation factor G, domain IV K02355 - - 4.938e-197 639.0
TH2_k127_8445453_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 454.0
TH2_k127_8445453_2 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 371.0
TH2_k127_8445453_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000003331 145.0
TH2_k127_8445453_4 Cold shock protein K03704 - - 0.0000000000000000000000000006703 113.0
TH2_k127_8445453_5 Binds directly to 16S ribosomal RNA K02968 - - 0.00000002209 60.0
TH2_k127_8445453_6 Outer membrane lipoprotein - - - 0.000004765 50.0
TH2_k127_8486545_0 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.00000000000000000000000003166 117.0
TH2_k127_8486545_1 Zn-ribbon protein, possibly nucleic acid-binding K07164 - - 0.00002215 55.0
TH2_k127_8503589_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000001132 183.0
TH2_k127_8503589_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000004828 71.0
TH2_k127_8503589_2 uridine kinase K00876 - 2.7.1.48 0.000000003901 67.0
TH2_k127_8533456_0 Oligopeptide transporter OPT - - - 5.819e-242 766.0
TH2_k127_8533456_1 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000003158 153.0
TH2_k127_8533456_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000006146 146.0
TH2_k127_8533456_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.000000000002695 74.0
TH2_k127_8547025_0 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002319 246.0
TH2_k127_8547025_1 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000006405 215.0
TH2_k127_8547025_2 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000003605 149.0
TH2_k127_8547025_3 Aminotransferase class-V - - - 0.000000002726 63.0
TH2_k127_8549121_0 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007274 254.0
TH2_k127_8549121_1 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000969 205.0
TH2_k127_8549121_2 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000095 205.0
TH2_k127_8552479_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 6.619e-231 724.0
TH2_k127_8552479_1 TIGRFAM 2-oxoglutarate dehydrogenase, E1 K00164,K01616 - 1.2.4.2,4.1.1.71 1.233e-212 675.0
TH2_k127_8552479_10 bacterial OsmY and nodulation domain - - - 0.00000006147 61.0
TH2_k127_8552479_2 Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 310.0
TH2_k127_8552479_3 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001901 213.0
TH2_k127_8552479_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000006817 182.0
TH2_k127_8552479_5 DoxX - - - 0.000000000000000000000000000000000000000005533 158.0
TH2_k127_8552479_6 Transglycosylase associated protein - - - 0.000000000000000000000000000003459 121.0
TH2_k127_8552479_7 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000002664 118.0
TH2_k127_8552479_8 Rubrerythrin - - - 0.000000000000000000000000006548 122.0
TH2_k127_8552479_9 PFAM DRTGG domain - - - 0.0000000000000001873 88.0
TH2_k127_8655372_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 328.0
TH2_k127_8655372_1 Peptidase family M23 K21471 - - 0.000000000000000000000000001342 131.0
TH2_k127_8655372_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0001966 52.0
TH2_k127_8705762_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 326.0
TH2_k127_8705762_1 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000139 226.0
TH2_k127_8705762_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000589 187.0
TH2_k127_8705762_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000005965 175.0
TH2_k127_8705762_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000000000000002563 123.0
TH2_k127_8705762_5 Tetratricopeptide repeats - - - 0.00000000000000000000000007026 124.0
TH2_k127_8705762_6 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000004039 110.0
TH2_k127_8705762_7 Ribosomal protein S16 K02959 - - 0.00000000000000001178 86.0
TH2_k127_8729663_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 366.0
TH2_k127_8729663_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 321.0
TH2_k127_8729663_2 glycoside hydrolase family 38 K01191 - 3.2.1.24 0.000000000000000000000000000000000000000009481 171.0
TH2_k127_8729663_3 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 0.0000000000000000000000008764 119.0
TH2_k127_8731140_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 526.0
TH2_k127_8731140_1 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 432.0
TH2_k127_8731140_10 Cytochrome b subunit of formate dehydrogenase-like protein - - - 0.00000000000000000000000000000001826 136.0
TH2_k127_8731140_11 PFAM peptidase M50 K16922 - - 0.0000000000000000000000000000007864 136.0
TH2_k127_8731140_12 Cyclic nucleotide-monophosphate binding domain K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.000000000000000000002767 103.0
TH2_k127_8731140_2 Transport of potassium into the cell K03549 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 390.0
TH2_k127_8731140_3 denitrification pathway K02569,K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 337.0
TH2_k127_8731140_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 326.0
TH2_k127_8731140_5 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000003531 252.0
TH2_k127_8731140_6 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000006721 218.0
TH2_k127_8731140_7 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.00000000000000000000000000000000000000000000000000000000949 209.0
TH2_k127_8731140_8 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.0000000000000000000000000000000000002602 154.0
TH2_k127_8731140_9 MgtC family K07507 - - 0.000000000000000000000000000000007786 136.0
TH2_k127_873642_0 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 478.0
TH2_k127_873642_1 haemagglutination activity domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 489.0
TH2_k127_8766169_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 488.0
TH2_k127_8766169_1 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 358.0
TH2_k127_8766169_2 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 299.0
TH2_k127_8766169_3 ABC transporter transmembrane K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001398 261.0
TH2_k127_8766169_4 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000001234 190.0
TH2_k127_8766169_5 PFAM Rieske 2Fe-2S domain protein K05710 - - 0.000000000000000000002045 100.0
TH2_k127_8766169_6 Heat shock protein DnaJ domain protein - - - 0.000000000000004249 87.0
TH2_k127_8804327_0 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001246 273.0
TH2_k127_8819581_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000001686 210.0
TH2_k127_8819581_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000008483 147.0
TH2_k127_8819581_2 metal-dependent phosphohydrolase HD region K07814 - - 0.00000000007122 72.0
TH2_k127_8819581_3 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0002776 49.0
TH2_k127_8836628_0 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000004685 175.0
TH2_k127_8878633_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 313.0
TH2_k127_8878633_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 334.0
TH2_k127_8878633_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000005044 61.0
TH2_k127_8891017_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000002516 94.0
TH2_k127_8891017_1 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000001269 96.0
TH2_k127_910218_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 489.0
TH2_k127_910218_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 366.0
TH2_k127_910218_2 pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 292.0
TH2_k127_910218_3 oxidoreductase gamma subunit K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000003903 203.0
TH2_k127_910218_4 Thioredoxin-like [2Fe-2S] ferredoxin - - - 0.0000000000000000000000000000000000000007789 153.0
TH2_k127_915344_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 612.0
TH2_k127_915344_1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K01802,K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000005911 228.0
TH2_k127_915344_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000005129 215.0
TH2_k127_915344_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000005216 174.0
TH2_k127_915344_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000007819 156.0
TH2_k127_915344_5 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000001045 123.0
TH2_k127_915344_6 PDZ domain - - - 0.000000000000000000000000000003951 134.0
TH2_k127_915344_7 - - - - 0.000587 51.0
TH2_k127_939688_0 COG0616 Periplasmic serine proteases (ClpP class) K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003471 272.0
TH2_k127_939688_1 metalloendopeptidase activity K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000002041 113.0
TH2_k127_98669_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000005004 252.0
TH2_k127_98669_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000001467 209.0
TH2_k127_98669_2 Peptidase family M23 K21471 - - 0.00000000000000000000000000007119 129.0
TH2_k127_991351_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 517.0
TH2_k127_991351_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000006167 166.0