Overview

ID MAG03923
Name TH2_bin.64
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Nitrosomonadaceae
Genus Nitrosomonas
Species
Assembly information
Completeness (%) 86.52
Contamination (%) 1.07
GC content (%) 45.0
N50 (bp) 16,365
Genome size (bp) 2,331,898

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2328

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_110583_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1170.0
TH2_k127_110583_1 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 377.0
TH2_k127_110583_2 SMART Diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 335.0
TH2_k127_1121590_0 Tetratricopeptide repeat - - - 0.0 1080.0
TH2_k127_1121590_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 1.5e-323 991.0
TH2_k127_1121590_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 394.0
TH2_k127_1121590_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 390.0
TH2_k127_1121590_12 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000000000000000000000000000000000001214 172.0
TH2_k127_1121590_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 5.814e-221 686.0
TH2_k127_1121590_3 Glycyl-tRNA synthetase K01878 - 6.1.1.14 4.751e-203 632.0
TH2_k127_1121590_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 8.366e-197 614.0
TH2_k127_1121590_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 537.0
TH2_k127_1121590_6 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 522.0
TH2_k127_1121590_7 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 467.0
TH2_k127_1121590_8 glycyl-tRNA aminoacylation K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 451.0
TH2_k127_1121590_9 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 413.0
TH2_k127_114578_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 6.314e-217 676.0
TH2_k127_114578_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 441.0
TH2_k127_114578_2 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 426.0
TH2_k127_114578_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 347.0
TH2_k127_114578_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008491 274.0
TH2_k127_114578_5 - - - - 0.00000000000000000000000000000000242 130.0
TH2_k127_1209262_0 Uncharacterized protein conserved in bacteria (DUF2130) - - - 1.704e-243 756.0
TH2_k127_1209262_1 Ribosomal RNA adenine dimethylase - - - 7.654e-202 629.0
TH2_k127_1209262_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 575.0
TH2_k127_1209262_3 PIN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001805 274.0
TH2_k127_1209262_4 PFAM Major facilitator superfamily MFS-1 - - - 0.00000000000000000000000000000000000001258 145.0
TH2_k127_1209262_5 PFAM Transposase IS3 IS911 K07483 - - 0.0000000000000000000000000000000000002706 141.0
TH2_k127_1209262_6 - - - - 0.0000000000000000000001354 102.0
TH2_k127_1274028_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1621.0
TH2_k127_1274028_1 NlpB/DapX lipoprotein K07287 - - 4.877e-229 711.0
TH2_k127_1274028_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 579.0
TH2_k127_1274028_3 SMART Diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000001367 210.0
TH2_k127_1275048_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1069.0
TH2_k127_1275048_1 Uncharacterized protein family (UPF0051) K09014 - - 1.444e-312 958.0
TH2_k127_1275048_10 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 371.0
TH2_k127_1275048_11 Scaffold protein Nfu/NifU N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 364.0
TH2_k127_1275048_12 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 310.0
TH2_k127_1275048_13 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 308.0
TH2_k127_1275048_14 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000001581 264.0
TH2_k127_1275048_15 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000000000000000004412 217.0
TH2_k127_1275048_16 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000002315 216.0
TH2_k127_1275048_17 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000106 195.0
TH2_k127_1275048_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 1.584e-259 801.0
TH2_k127_1275048_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 2.031e-251 781.0
TH2_k127_1275048_4 Uncharacterized protein family (UPF0051) K09015 - - 4.441e-250 775.0
TH2_k127_1275048_5 - - - - 1.185e-247 766.0
TH2_k127_1275048_6 Uncharacterized protein conserved in bacteria (DUF2331) - - - 1.209e-224 698.0
TH2_k127_1275048_7 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 3.161e-203 634.0
TH2_k127_1275048_8 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 503.0
TH2_k127_1275048_9 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 436.0
TH2_k127_1356142_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1142.0
TH2_k127_1356142_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 5.948e-281 864.0
TH2_k127_1356142_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 527.0
TH2_k127_1356142_3 Cytochrome c - - - 0.0000000000000000000000003258 108.0
TH2_k127_1356142_4 - - - - 0.00000000000000005706 81.0
TH2_k127_136035_0 Protein conserved in bacteria K20274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 352.0
TH2_k127_136035_1 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002305 263.0
TH2_k127_136035_2 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000001212 124.0
TH2_k127_139350_0 TonB-dependent receptor K16090 - - 0.0 1256.0
TH2_k127_139350_1 - - - - 0.0 1084.0
TH2_k127_139350_2 Cytidylyltransferase-like - - - 8.63e-305 938.0
TH2_k127_139350_3 PFAM transposase, IS4 family protein K07481 - - 1.534e-218 686.0
TH2_k127_139350_4 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000001336 179.0
TH2_k127_139350_5 2Fe-2S -binding K02192 - - 0.0000000000000000000000000004554 114.0
TH2_k127_139350_6 Thioredoxin-like domain K03671,K03672 - 1.8.1.8 0.0000000000005034 71.0
TH2_k127_1393575_0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000000002512 207.0
TH2_k127_1393575_1 Protein of unknown function (DUF4056) - - - 0.00000000000000000000003067 111.0
TH2_k127_1406285_0 ABC-type uncharacterized transport system - - - 2.415e-268 828.0
TH2_k127_1406285_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008106 513.0
TH2_k127_1406285_2 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 502.0
TH2_k127_1406285_3 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 449.0
TH2_k127_1406285_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 422.0
TH2_k127_1407869_0 Histidine kinase K20974 - 2.7.13.3 0.0 1392.0
TH2_k127_1407869_1 Putative diguanylate phosphodiesterase - - - 2.743e-211 662.0
TH2_k127_1407869_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 351.0
TH2_k127_1407869_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009551 280.0
TH2_k127_1407869_4 Bacterial transcriptional repressor C-terminal K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002309 259.0
TH2_k127_1408627_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1575.0
TH2_k127_1408627_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1296.0
TH2_k127_1408627_2 Participates in both transcription termination and antitermination K02600 - - 2.483e-299 920.0
TH2_k127_1408627_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 304.0
TH2_k127_1408627_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002121 251.0
TH2_k127_1408627_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000001669 138.0
TH2_k127_1412915_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000007063 144.0
TH2_k127_1412915_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000007288 127.0
TH2_k127_1412915_2 Prokaryotic N-terminal methylation motif - - - 0.00001657 55.0
TH2_k127_141932_0 Biotin-lipoyl like K01993,K16922 - - 0.0 1478.0
TH2_k127_141932_1 Dynamin family - - - 3.55e-305 937.0
TH2_k127_141932_2 Outer membrane efflux protein K18139 - - 2.911e-287 885.0
TH2_k127_141932_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 2.231e-237 734.0
TH2_k127_141932_4 Sulfotransferase family - - - 1.899e-201 627.0
TH2_k127_141932_5 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 578.0
TH2_k127_141932_6 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 292.0
TH2_k127_141932_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006365 258.0
TH2_k127_141932_8 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000004753 95.0
TH2_k127_141932_9 - - - - 0.000000000000000000002719 93.0
TH2_k127_143672_0 PFAM Phospholipid glycerol acyltransferase - - - 0.0 1143.0
TH2_k127_143672_1 SMART ATPase, AAA type, core K01551 - 3.6.3.16 9.343e-305 937.0
TH2_k127_143672_2 Peptidase M14, carboxypeptidase A - - - 3.684e-217 674.0
TH2_k127_143672_3 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 580.0
TH2_k127_143672_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 562.0
TH2_k127_143672_5 PFAM Alpha beta hydrolase fold-1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 449.0
TH2_k127_143672_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000000000000000000000234 143.0
TH2_k127_1542660_0 ATPase involved in DNA repair K03546 GO:0000014,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576,GO:1990238 - 0.0 1034.0
TH2_k127_1542660_1 Transposase - - - 8.083e-304 962.0
TH2_k127_1542660_10 Helix-turn-helix domain of resolvase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004818 252.0
TH2_k127_1542660_11 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000007951 215.0
TH2_k127_1542660_12 Plasmid stabilization system - - - 0.0000000000000000000000000000000000000000000000000000000008357 202.0
TH2_k127_1542660_13 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000000000147 163.0
TH2_k127_1542660_14 Signal peptidase, peptidase S26 - - - 0.00000000000000000000000000000000000000002225 157.0
TH2_k127_1542660_15 TRAG family K03205 - - 0.00000000000000000000000000000000002119 136.0
TH2_k127_1542660_16 HNH endonuclease - - - 0.00000000000000000000000000000000002947 137.0
TH2_k127_1542660_17 sequence-specific DNA binding - - - 0.00000000000000000000000000000522 121.0
TH2_k127_1542660_18 peptidase S8 and S53, subtilisin, kexin, sedolisin K20754 - 3.4.21.111 0.0000000000000000000000000001031 124.0
TH2_k127_1542660_19 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.00000000000000000000002723 102.0
TH2_k127_1542660_2 Phage integrase, N-terminal SAM-like domain - - - 4.375e-195 609.0
TH2_k127_1542660_20 Signal peptidase, peptidase S26 - - - 0.0000000000000000003167 89.0
TH2_k127_1542660_21 Plasmid pRiA4b ORF-3-like protein - - - 0.00000000000000547 75.0
TH2_k127_1542660_22 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000001416 52.0
TH2_k127_1542660_3 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 594.0
TH2_k127_1542660_4 Transposase zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 511.0
TH2_k127_1542660_5 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 501.0
TH2_k127_1542660_6 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 389.0
TH2_k127_1542660_7 Urea transporter K08717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 364.0
TH2_k127_1542660_8 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 299.0
TH2_k127_1542660_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 285.0
TH2_k127_1552796_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 541.0
TH2_k127_1552796_1 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 495.0
TH2_k127_1552796_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000001923 128.0
TH2_k127_1552796_3 Belongs to the universal stress protein A family - - - 0.00000000000000001172 82.0
TH2_k127_1552796_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000007298 50.0
TH2_k127_157947_0 Bacterial protein of unknown function (DUF839) K07093 - - 1.244e-262 813.0
TH2_k127_157947_1 Belongs to the GcvT family K06980 - - 2.23e-212 662.0
TH2_k127_157947_2 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 460.0
TH2_k127_157947_3 - K19168 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004301 256.0
TH2_k127_157947_5 Dynamin family - - - 0.00000000000000305 75.0
TH2_k127_157947_6 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K00057 - 1.1.1.94 0.0000000002899 61.0
TH2_k127_1600436_0 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1474.0
TH2_k127_1600436_1 Belongs to the GSP D family K02666 - - 0.0 1210.0
TH2_k127_1600436_10 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 541.0
TH2_k127_1600436_11 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 534.0
TH2_k127_1600436_12 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 475.0
TH2_k127_1600436_13 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 466.0
TH2_k127_1600436_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 433.0
TH2_k127_1600436_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 430.0
TH2_k127_1600436_16 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000085 430.0
TH2_k127_1600436_17 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 394.0
TH2_k127_1600436_18 2'-5' RNA ligase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 394.0
TH2_k127_1600436_19 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 381.0
TH2_k127_1600436_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 5.854e-267 824.0
TH2_k127_1600436_20 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 375.0
TH2_k127_1600436_21 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 376.0
TH2_k127_1600436_22 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 372.0
TH2_k127_1600436_23 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 364.0
TH2_k127_1600436_24 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008547 355.0
TH2_k127_1600436_25 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 341.0
TH2_k127_1600436_26 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 339.0
TH2_k127_1600436_27 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 332.0
TH2_k127_1600436_28 PFAM Fimbrial assembly K02663 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 326.0
TH2_k127_1600436_29 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 310.0
TH2_k127_1600436_3 TIGRFAM type IV pilus assembly protein PilM K02662 - - 5.475e-222 690.0
TH2_k127_1600436_30 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 295.0
TH2_k127_1600436_31 PFAM Pilus assembly protein K02665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 292.0
TH2_k127_1600436_32 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 291.0
TH2_k127_1600436_33 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006608 246.0
TH2_k127_1600436_34 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005325 241.0
TH2_k127_1600436_35 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000000000005349 228.0
TH2_k127_1600436_36 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000000000002165 228.0
TH2_k127_1600436_37 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000000000000000008754 225.0
TH2_k127_1600436_38 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000004218 225.0
TH2_k127_1600436_39 - - - - 0.0000000000000000000000000000000000000000000000000000000000000282 216.0
TH2_k127_1600436_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 7.915e-210 656.0
TH2_k127_1600436_40 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000000000000000000000000000000000481 211.0
TH2_k127_1600436_41 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000000000004901 210.0
TH2_k127_1600436_42 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000000001951 203.0
TH2_k127_1600436_43 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000000000000904 203.0
TH2_k127_1600436_44 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000000000002071 188.0
TH2_k127_1600436_45 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000001034 186.0
TH2_k127_1600436_46 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000000000000000000004637 174.0
TH2_k127_1600436_47 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000004981 175.0
TH2_k127_1600436_48 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000000000318 158.0
TH2_k127_1600436_49 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000000664 151.0
TH2_k127_1600436_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 1.061e-208 649.0
TH2_k127_1600436_50 Domain of unknown function (DUF4177) - - - 0.00000000000000000000000000000000000001705 143.0
TH2_k127_1600436_51 Ribosomal protein L30 K02907 - - 0.0000000000000000000000003802 106.0
TH2_k127_1600436_52 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000005157 80.0
TH2_k127_1600436_53 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000001141 81.0
TH2_k127_1600436_54 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000001341 79.0
TH2_k127_1600436_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 7.045e-206 642.0
TH2_k127_1600436_7 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 5.171e-195 610.0
TH2_k127_1600436_8 Signal transduction response regulator, receiver K03415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 586.0
TH2_k127_1600436_9 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 583.0
TH2_k127_1736923_0 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.0 1045.0
TH2_k127_1736923_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 6.209e-320 981.0
TH2_k127_1736923_10 Flagellar basal body rod protein K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 547.0
TH2_k127_1736923_11 Belongs to the flagella basal body rod proteins family K02391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 447.0
TH2_k127_1736923_12 Belongs to the flagella basal body rod proteins family K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 442.0
TH2_k127_1736923_13 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 428.0
TH2_k127_1736923_14 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 427.0
TH2_k127_1736923_15 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 425.0
TH2_k127_1736923_16 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 412.0
TH2_k127_1736923_17 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 373.0
TH2_k127_1736923_18 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002541 259.0
TH2_k127_1736923_19 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004835 247.0
TH2_k127_1736923_2 Belongs to the GARS family K01945 - 6.3.4.13 8.225e-267 825.0
TH2_k127_1736923_20 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001364 231.0
TH2_k127_1736923_21 PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000009405 204.0
TH2_k127_1736923_22 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000000000000000000000000000000000008165 156.0
TH2_k127_1736923_23 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000000002787 147.0
TH2_k127_1736923_24 response regulator K02282,K07689 - - 0.000000000000000000000000000000000001832 147.0
TH2_k127_1736923_3 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 3.441e-234 727.0
TH2_k127_1736923_4 DeoC/LacD family aldolase K11645 - 4.1.2.13 5.881e-224 694.0
TH2_k127_1736923_5 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 4.423e-218 679.0
TH2_k127_1736923_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 3.448e-208 648.0
TH2_k127_1736923_7 Bacterial flagellin N-terminal helical region K02397 - - 7.497e-208 651.0
TH2_k127_1736923_8 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 610.0
TH2_k127_1736923_9 Rod binding protein K02395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 593.0
TH2_k127_1783283_0 Signal transduction histidine kinase K07636 - 2.7.13.3 3.195e-266 821.0
TH2_k127_1783283_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 490.0
TH2_k127_1783283_2 TIGRFAM Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 460.0
TH2_k127_1783283_3 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002398 277.0
TH2_k127_1783283_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002707 237.0
TH2_k127_1783283_5 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000002585 104.0
TH2_k127_1783283_6 HTH-like domain K07497 - - 0.0000000000000000002708 87.0
TH2_k127_1783283_7 PFAM Integrase, catalytic core K07497 - - 0.000000000000000006512 82.0
TH2_k127_1800274_0 HELICc2 K03722 - 3.6.4.12 0.0 1223.0
TH2_k127_1800274_1 DNA helicase K03654 - 3.6.4.12 0.0 1144.0
TH2_k127_1800274_10 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 311.0
TH2_k127_1800274_11 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 327.0
TH2_k127_1800274_12 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 290.0
TH2_k127_1800274_13 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004727 279.0
TH2_k127_1800274_14 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002859 254.0
TH2_k127_1800274_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000518 216.0
TH2_k127_1800274_16 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000000000000002813 199.0
TH2_k127_1800274_17 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000000000003987 169.0
TH2_k127_1800274_18 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000000000000000000000000000001072 164.0
TH2_k127_1800274_19 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000001338 164.0
TH2_k127_1800274_2 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor K02668 - 2.7.13.3 0.0 998.0
TH2_k127_1800274_20 - K06950 - - 0.00000000000000000000000000000000000000649 145.0
TH2_k127_1800274_21 - - - - 0.000000000000000000000000000000008453 126.0
TH2_k127_1800274_22 Transposase DDE domain - - - 0.000000000000000000000000006032 109.0
TH2_k127_1800274_23 nuclear chromosome segregation - - - 0.00000000000000000011 92.0
TH2_k127_1800274_3 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.877e-313 960.0
TH2_k127_1800274_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 6.905e-224 695.0
TH2_k127_1800274_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 2.889e-218 678.0
TH2_k127_1800274_6 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 7.829e-209 650.0
TH2_k127_1800274_7 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 2.706e-195 610.0
TH2_k127_1800274_8 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 494.0
TH2_k127_1800274_9 response regulator receiver K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 456.0
TH2_k127_1800277_0 pilus assembly protein FimV K08086 - - 0.0 1238.0
TH2_k127_1800277_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0 998.0
TH2_k127_1800277_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 503.0
TH2_k127_1800277_11 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 413.0
TH2_k127_1800277_12 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 395.0
TH2_k127_1800277_13 Sporulation related domain K03749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 350.0
TH2_k127_1800277_14 Colicin V production K03558 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 299.0
TH2_k127_1800277_15 Transposase DDE domain - - - 0.00000000000000000000000002145 108.0
TH2_k127_1800277_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.704e-282 867.0
TH2_k127_1800277_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 6.105e-263 810.0
TH2_k127_1800277_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 1.777e-260 805.0
TH2_k127_1800277_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 4.372e-243 752.0
TH2_k127_1800277_6 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 2.496e-239 740.0
TH2_k127_1800277_7 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 6.939e-215 668.0
TH2_k127_1800277_8 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 571.0
TH2_k127_1800277_9 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 532.0
TH2_k127_1844612_0 Ammonium transporter K03320,K06580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 547.0
TH2_k127_1844612_1 Protein of unknown function (DUF1826) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 359.0
TH2_k127_1844612_2 Belongs to the Fur family K09823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 293.0
TH2_k127_1844612_3 Cobalamin synthesis protein cobW C-terminal domain - - - 0.000000000000001885 75.0
TH2_k127_1849904_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 2073.0
TH2_k127_1849904_1 Cytochrome c1 - - - 0.0 1257.0
TH2_k127_1849904_10 Belongs to the CarA family K01956 - 6.3.5.5 7.419e-247 763.0
TH2_k127_1849904_11 TIGRFAM phosphate binding protein K02040 - - 5.564e-201 627.0
TH2_k127_1849904_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 583.0
TH2_k127_1849904_13 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 502.0
TH2_k127_1849904_14 PFAM Integrase, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 486.0
TH2_k127_1849904_15 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 460.0
TH2_k127_1849904_16 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 454.0
TH2_k127_1849904_17 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 394.0
TH2_k127_1849904_18 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 295.0
TH2_k127_1849904_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 292.0
TH2_k127_1849904_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1241.0
TH2_k127_1849904_20 CRS1_YhbY K07574 - - 0.00000000000000000000000000000000000000000000000000000000002282 207.0
TH2_k127_1849904_21 PFAM transposase IS3 IS911 family protein K07483 - - 0.0000000000000000000000000000000000000000000000004238 176.0
TH2_k127_1849904_22 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000007113 155.0
TH2_k127_1849904_25 SMART Diguanylate phosphodiesterase - - - 0.000000000009657 66.0
TH2_k127_1849904_3 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.0 1174.0
TH2_k127_1849904_4 Belongs to the glutamate synthase family - - - 6.98e-321 983.0
TH2_k127_1849904_5 TIGRFAM Acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 3.479e-303 934.0
TH2_k127_1849904_6 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 4.589e-292 897.0
TH2_k127_1849904_7 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 5.8e-283 872.0
TH2_k127_1849904_8 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 3.85e-280 867.0
TH2_k127_1849904_9 Cytochrome P450 - - - 1.811e-275 848.0
TH2_k127_1882877_0 PFAM Peptidase M16 K07263 - - 7.706e-283 873.0
TH2_k127_1882877_1 PFAM Peptidase M48 K06013 - 3.4.24.84 6.416e-259 799.0
TH2_k127_1882877_10 EF hand - - - 0.0000000000000000000000000000000000000000000000000000001332 201.0
TH2_k127_1882877_2 Belongs to the 'phage' integrase family - - - 3.6e-213 665.0
TH2_k127_1882877_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 1.317e-198 621.0
TH2_k127_1882877_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 521.0
TH2_k127_1882877_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 501.0
TH2_k127_1882877_6 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 417.0
TH2_k127_1882877_7 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 379.0
TH2_k127_1882877_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000001879 261.0
TH2_k127_1882877_9 diol metabolic process K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000000000000000000000000000005547 232.0
TH2_k127_20475_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000006064 183.0
TH2_k127_20475_1 Sigma-70 region 2 K03088 - - 0.000000000000003616 86.0
TH2_k127_2238253_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 3.615e-312 957.0
TH2_k127_2238253_1 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 2.849e-295 908.0
TH2_k127_2238253_10 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 488.0
TH2_k127_2238253_11 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 476.0
TH2_k127_2238253_12 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 454.0
TH2_k127_2238253_13 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 447.0
TH2_k127_2238253_14 Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 390.0
TH2_k127_2238253_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 382.0
TH2_k127_2238253_16 PFAM Sporulation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 358.0
TH2_k127_2238253_17 low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 317.0
TH2_k127_2238253_18 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 304.0
TH2_k127_2238253_19 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000002599 261.0
TH2_k127_2238253_2 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 1.173e-275 849.0
TH2_k127_2238253_20 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002847 259.0
TH2_k127_2238253_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000001765 215.0
TH2_k127_2238253_22 Thiamine monophosphate synthase - - - 0.000000000000000000000000000000000000000000000000000000006351 205.0
TH2_k127_2238253_23 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000000000000003054 143.0
TH2_k127_2238253_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 - 6.2.1.5,6.2.1.9 4.485e-243 753.0
TH2_k127_2238253_4 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 5.147e-239 739.0
TH2_k127_2238253_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5,6.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 579.0
TH2_k127_2238253_6 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 552.0
TH2_k127_2238253_7 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 549.0
TH2_k127_2238253_8 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 547.0
TH2_k127_2238253_9 restriction endonuclease K07448 GO:0001101,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009295,GO:0009415,GO:0009628,GO:0009987,GO:0010035,GO:0015666,GO:0016787,GO:0016788,GO:0032067,GO:0034641,GO:0042221,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051599,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 496.0
TH2_k127_2288943_0 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000002654 154.0
TH2_k127_2288943_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000002378 156.0
TH2_k127_2288943_2 - - - - 0.00000000001192 70.0
TH2_k127_2305197_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 511.0
TH2_k127_2305197_1 Type II restriction enzyme, methylase subunits - - - 0.000000000000000000000000000000000000008612 147.0
TH2_k127_2305344_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000009336 229.0
TH2_k127_2305344_1 Protein of unknown function (DUF2878) - - - 0.000000000000000007567 91.0
TH2_k127_2322776_0 - - - - 3.891e-226 711.0
TH2_k127_2322776_1 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 576.0
TH2_k127_2322776_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000005269 206.0
TH2_k127_2391889_0 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.0 1480.0
TH2_k127_2391889_1 chain 5 L K00341 - 1.6.5.3 0.0 1234.0
TH2_k127_2391889_10 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 575.0
TH2_k127_2391889_11 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 504.0
TH2_k127_2391889_12 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 458.0
TH2_k127_2391889_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 388.0
TH2_k127_2391889_14 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 361.0
TH2_k127_2391889_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 338.0
TH2_k127_2391889_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 336.0
TH2_k127_2391889_17 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 316.0
TH2_k127_2391889_18 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 290.0
TH2_k127_2391889_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002201 235.0
TH2_k127_2391889_2 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1173.0
TH2_k127_2391889_20 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000000000000000000000000002784 198.0
TH2_k127_2391889_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000000000001058 178.0
TH2_k127_2391889_23 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000003298 99.0
TH2_k127_2391889_24 BNR repeat-like domain - - - 0.0002646 46.0
TH2_k127_2391889_3 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 4.704e-311 954.0
TH2_k127_2391889_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.263e-293 899.0
TH2_k127_2391889_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 2.029e-287 885.0
TH2_k127_2391889_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 5.665e-280 860.0
TH2_k127_2391889_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 3.812e-226 703.0
TH2_k127_2391889_8 Phosphate transport system permease protein K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 579.0
TH2_k127_2391889_9 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 576.0
TH2_k127_2452618_0 Subtilase family K08651,K14645 - 3.4.21.66 1.213e-246 765.0
TH2_k127_2452618_1 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 502.0
TH2_k127_2452618_2 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 394.0
TH2_k127_2452618_3 PFAM RNA polymerase sigma factor 70, region 4 type 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 390.0
TH2_k127_2452618_4 GGDEF domain - - - 0.0000000000000000000000000000000000000000000003405 168.0
TH2_k127_2452618_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000007103 143.0
TH2_k127_2452618_6 PFAM transposase, mutator type - - - 0.0000000000007907 70.0
TH2_k127_2520656_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.0 1115.0
TH2_k127_2520656_1 ABC transporter K06020 - 3.6.3.25 0.0 1078.0
TH2_k127_2520656_10 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 580.0
TH2_k127_2520656_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 576.0
TH2_k127_2520656_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007088 505.0
TH2_k127_2520656_13 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 456.0
TH2_k127_2520656_14 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 453.0
TH2_k127_2520656_15 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 297.0
TH2_k127_2520656_16 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001647 278.0
TH2_k127_2520656_17 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000001148 231.0
TH2_k127_2520656_19 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000000000000000000000000000000000000003243 185.0
TH2_k127_2520656_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 5.711e-310 952.0
TH2_k127_2520656_20 POTRA domain, FtsQ-type - - - 0.00000000000000000000000000000000000001597 154.0
TH2_k127_2520656_21 Protein of unknown function (DUF2835) - - - 0.00000000000000000000000000000000000001947 144.0
TH2_k127_2520656_22 Peptidase M4 - - - 0.00000000000000000000000000001035 118.0
TH2_k127_2520656_23 - - - - 0.0000000000000000000000006179 104.0
TH2_k127_2520656_24 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000008964 94.0
TH2_k127_2520656_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.13e-301 927.0
TH2_k127_2520656_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 7.169e-294 903.0
TH2_k127_2520656_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 9.728e-270 834.0
TH2_k127_2520656_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 3.962e-263 811.0
TH2_k127_2520656_7 Peptidoglycan polymerase that is essential for cell division K03588 - - 6.843e-232 719.0
TH2_k127_2520656_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1.166e-230 716.0
TH2_k127_2520656_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 597.0
TH2_k127_2551568_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0 1102.0
TH2_k127_2551568_1 InterPro IPR002559 COGs COG3293 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 347.0
TH2_k127_2551568_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008963 267.0
TH2_k127_2551568_3 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001485 267.0
TH2_k127_2551568_4 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000002641 127.0
TH2_k127_2572219_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0 1334.0
TH2_k127_2572219_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 609.0
TH2_k127_2572219_2 PFAM RIO-like kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 540.0
TH2_k127_2572219_3 antibiotic catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 456.0
TH2_k127_2572219_4 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000005253 151.0
TH2_k127_2572219_5 Putative quorum-sensing-regulated virulence factor K09954 - - 0.00000000000000000000000000000000000000251 146.0
TH2_k127_2572219_6 PFAM Transposase, IS4-like - - - 0.000008409 48.0
TH2_k127_2575963_0 fatty acid desaturase K00507 - 1.14.19.1 5.147e-258 796.0
TH2_k127_2575963_1 Belongs to the Dps family K03594 - 1.16.3.1 0.00000000000002828 72.0
TH2_k127_2606959_0 Flagellar hook-length control protein FliK - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 590.0
TH2_k127_2606959_1 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 524.0
TH2_k127_2606959_2 flagellar protein FliS K02422 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003559 256.0
TH2_k127_2606959_3 Flagellar protein FliT K02423 - - 0.0000000000000000000000000000000000000000000000000000000000007457 210.0
TH2_k127_2606959_4 FlhB HrpN YscU SpaS Family K04061 - - 0.0000000000001373 71.0
TH2_k127_262840_0 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003195 265.0
TH2_k127_262840_1 COG3547 Transposase and inactivated derivatives - - - 0.0000000000000000000473 94.0
TH2_k127_262840_2 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000007836 68.0
TH2_k127_262840_3 GYD domain - - - 0.0000009344 50.0
TH2_k127_262840_4 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.0003617 44.0
TH2_k127_2645901_0 lipid kinase activity - - - 0.0 1173.0
TH2_k127_2645901_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0 1115.0
TH2_k127_2645901_10 PFAM Glycoside hydrolase, family 19, catalytic K03791 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 330.0
TH2_k127_2645901_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002364 279.0
TH2_k127_2645901_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004811 273.0
TH2_k127_2645901_13 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000101 262.0
TH2_k127_2645901_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004873 249.0
TH2_k127_2645901_15 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000002905 201.0
TH2_k127_2645901_16 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000002752 69.0
TH2_k127_2645901_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 5.314e-264 814.0
TH2_k127_2645901_3 PFAM Permease YjgP YjgQ K07091 - - 5.628e-204 637.0
TH2_k127_2645901_4 PFAM Permease YjgP YjgQ K11720 - - 1.941e-203 638.0
TH2_k127_2645901_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 541.0
TH2_k127_2645901_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 494.0
TH2_k127_2645901_7 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 413.0
TH2_k127_2645901_8 Protein of unknown function (DUF2959) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 362.0
TH2_k127_2645901_9 YaeQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 347.0
TH2_k127_26489_0 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit - - - 2.815e-195 633.0
TH2_k127_26489_1 Aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 424.0
TH2_k127_26489_10 Transposase and inactivated derivatives - - - 0.00000001552 59.0
TH2_k127_26489_2 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 331.0
TH2_k127_26489_3 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 296.0
TH2_k127_26489_4 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003074 246.0
TH2_k127_26489_5 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000000000000000002802 240.0
TH2_k127_26489_6 purine nucleotide biosynthetic process K02529 - - 0.00000000000000000000000000000000000000000000000005193 191.0
TH2_k127_26489_7 L-rhamnose-proton symport protein (RhaT) K02856 - - 0.000000000000000000000000000000000000000000009329 175.0
TH2_k127_26489_8 Creatinase/Prolidase N-terminal domain K08688 - 3.5.3.3 0.00000000000000000000000000000000000000000001287 177.0
TH2_k127_26489_9 transcriptional regulator K13637 - - 0.0000000000000000000000001988 117.0
TH2_k127_2670581_0 Belongs to the peptidase S16 family - - - 0.0 1166.0
TH2_k127_2670581_1 Heat shock 70 kDa protein K04043 - - 0.0 1035.0
TH2_k127_2670581_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 406.0
TH2_k127_2680012_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 1.31e-233 728.0
TH2_k127_2680012_1 LppC putative lipoprotein K07121 - - 8.846e-216 676.0
TH2_k127_2680012_10 PFAM Transposase, IS4-like K07481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 331.0
TH2_k127_2680012_11 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002758 239.0
TH2_k127_2680012_12 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000001441 218.0
TH2_k127_2680012_13 - - - - 0.000000000000000000000000000000000000000000000002069 175.0
TH2_k127_2680012_14 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000001325 103.0
TH2_k127_2680012_16 pathogenesis K01119 - 3.1.3.6,3.1.4.16 0.00001262 49.0
TH2_k127_2680012_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 3.324e-208 649.0
TH2_k127_2680012_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 4.404e-207 646.0
TH2_k127_2680012_4 'signal transduction protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 560.0
TH2_k127_2680012_5 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 497.0
TH2_k127_2680012_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 499.0
TH2_k127_2680012_7 Short-chain dehydrogenase reductase SDR K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 479.0
TH2_k127_2680012_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 432.0
TH2_k127_2680012_9 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 377.0
TH2_k127_2692062_0 Double sensory domain of two-component sensor kinase - - - 0.0 1071.0
TH2_k127_2692062_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 358.0
TH2_k127_2692751_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1937.0
TH2_k127_2692751_1 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.0 1418.0
TH2_k127_2692751_10 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 357.0
TH2_k127_2692751_11 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 354.0
TH2_k127_2692751_12 Zeta toxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 282.0
TH2_k127_2692751_13 - K07039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005576 265.0
TH2_k127_2692751_14 ParD-like antitoxin of type II bacterial toxin-antitoxin system - - - 0.00000000000000000000000000000000000000001897 156.0
TH2_k127_2692751_15 DNA-binding protein VF530 - - - 0.00000000000000000000000000000000000000007411 156.0
TH2_k127_2692751_16 RNA-binding K14761 - - 0.0000000000000000000000000000000000007623 139.0
TH2_k127_2692751_17 HIRAN - - - 0.0000000000000000000000000000001871 128.0
TH2_k127_2692751_18 Metal dependent phosphohydrolases with conserved 'HD' motif. K07012 - - 0.000000000000000000000000013 115.0
TH2_k127_2692751_19 Protein of unknown function (DUF433) - - - 0.0000000000000000000141 94.0
TH2_k127_2692751_2 Belongs to the DEAD box helicase family - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 2.184e-288 887.0
TH2_k127_2692751_21 PFAM peptidase - - - 0.0000000003942 60.0
TH2_k127_2692751_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 4.704e-284 874.0
TH2_k127_2692751_4 ABC transporter K02021,K11085 - - 6.874e-280 869.0
TH2_k127_2692751_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 1.897e-243 754.0
TH2_k127_2692751_6 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 1.386e-197 617.0
TH2_k127_2692751_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 489.0
TH2_k127_2692751_8 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 367.0
TH2_k127_2692751_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 358.0
TH2_k127_2864370_0 Protein of unknown function (DUF502) - - - 0.00001912 52.0
TH2_k127_291667_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1748.0
TH2_k127_291667_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1352.0
TH2_k127_291667_10 - - - - 0.00001208 48.0
TH2_k127_291667_11 TIGRFAM phosphate binding protein K02040 - - 0.0003703 43.0
TH2_k127_291667_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0 1239.0
TH2_k127_291667_3 Phosphate-selective porin O and P K07221 - - 3.106e-318 979.0
TH2_k127_291667_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 286.0
TH2_k127_291667_5 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 280.0
TH2_k127_291667_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000000000000002501 173.0
TH2_k127_291667_7 - - - - 0.000000000000000004952 88.0
TH2_k127_291667_8 - - - - 0.00000001195 56.0
TH2_k127_291667_9 - - - - 0.000004884 52.0
TH2_k127_295986_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0 1196.0
TH2_k127_295986_1 Belongs to the 'phage' integrase family - - - 1.902e-236 735.0
TH2_k127_295986_10 Transcriptional regulator - - - 0.00000000000000000000000000000000000000001027 153.0
TH2_k127_295986_11 - - - - 0.000000000000000000000000003135 121.0
TH2_k127_295986_12 - - - - 0.0000000000000001658 79.0
TH2_k127_295986_14 - - - - 0.00000002288 64.0
TH2_k127_295986_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 1.252e-232 720.0
TH2_k127_295986_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 3.188e-207 646.0
TH2_k127_295986_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 555.0
TH2_k127_295986_5 Plasmid recombination enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 422.0
TH2_k127_295986_6 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 364.0
TH2_k127_295986_7 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003542 252.0
TH2_k127_295986_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001182 235.0
TH2_k127_295986_9 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000704 164.0
TH2_k127_3013358_0 COG1035 Coenzyme F420-reducing hydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 421.0
TH2_k127_3013358_1 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 378.0
TH2_k127_3013358_10 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000002076 195.0
TH2_k127_3013358_11 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000212 199.0
TH2_k127_3013358_12 Capsule synthesis protein K07282 - - 0.000000000000000000000000000000000000000000006721 177.0
TH2_k127_3013358_13 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000007641 160.0
TH2_k127_3013358_14 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000304 141.0
TH2_k127_3013358_15 Lysophospholipase l1-like esterase - - - 0.0000000000000000000000000000002762 133.0
TH2_k127_3013358_16 PFAM Oligosaccharide biosynthesis protein Alg14 like - - - 0.000000000000000000000000000007326 126.0
TH2_k127_3013358_17 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000002464 123.0
TH2_k127_3013358_18 NHL repeat - - - 0.00000000000000000000000516 121.0
TH2_k127_3013358_19 Polysaccharide biosynthesis protein - - - 0.00000000000000000000002562 115.0
TH2_k127_3013358_2 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 351.0
TH2_k127_3013358_20 sh3 domain protein - - - 0.00000005138 68.0
TH2_k127_3013358_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 308.0
TH2_k127_3013358_4 biosynthesis protein K16710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003151 295.0
TH2_k127_3013358_5 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005184 257.0
TH2_k127_3013358_6 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000001129 244.0
TH2_k127_3013358_7 COG0438 Glycosyltransferase K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000002554 241.0
TH2_k127_3013358_8 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000003211 222.0
TH2_k127_3013358_9 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000006432 218.0
TH2_k127_3046887_0 Polysaccharide biosynthesis protein - - - 9.285e-270 831.0
TH2_k127_3046887_1 - - - - 0.0000000003727 60.0
TH2_k127_3046887_2 Transposase domain (DUF772) - - - 0.000001373 50.0
TH2_k127_3208222_0 DnaJ molecular chaperone homology domain - - - 1.93e-214 669.0
TH2_k127_3208222_1 Peroxide stress protein YaaA K09861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 494.0
TH2_k127_3208222_2 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000009748 231.0
TH2_k127_3208222_3 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000003595 130.0
TH2_k127_3216915_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0 1256.0
TH2_k127_3216915_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.926e-314 963.0
TH2_k127_3216915_10 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 1.915e-205 641.0
TH2_k127_3216915_11 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 601.0
TH2_k127_3216915_12 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 567.0
TH2_k127_3216915_13 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 554.0
TH2_k127_3216915_14 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 505.0
TH2_k127_3216915_15 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 495.0
TH2_k127_3216915_16 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 460.0
TH2_k127_3216915_17 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 397.0
TH2_k127_3216915_18 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 383.0
TH2_k127_3216915_19 protein conserved in bacteria K03690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 363.0
TH2_k127_3216915_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 5.73e-308 945.0
TH2_k127_3216915_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 361.0
TH2_k127_3216915_21 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 346.0
TH2_k127_3216915_22 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 343.0
TH2_k127_3216915_23 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001702 245.0
TH2_k127_3216915_24 Uncharacterised BCR, YnfA/UPF0060 family K09771 - - 0.00000000000000000000000000000000000000000000000000000000000000006585 222.0
TH2_k127_3216915_25 Sigma 54 modulation protein K05808 - - 0.00000000000000000000000000000000000000000000000000000000008136 207.0
TH2_k127_3216915_26 shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000008162 197.0
TH2_k127_3216915_27 FlhB HrpN YscU SpaS Family K04061 - - 0.000000000000000000000000000000000000000000000000007116 181.0
TH2_k127_3216915_28 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000002565 173.0
TH2_k127_3216915_29 PFAM Modulator of Rho-dependent transcription termination K19000 - - 0.0000000000000000000000000000000000000000000158 164.0
TH2_k127_3216915_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.628e-301 927.0
TH2_k127_3216915_30 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.000006558 49.0
TH2_k127_3216915_31 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.00001655 49.0
TH2_k127_3216915_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 8.365e-283 872.0
TH2_k127_3216915_5 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 2.828e-243 753.0
TH2_k127_3216915_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 8.984e-235 727.0
TH2_k127_3216915_7 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 1.073e-219 684.0
TH2_k127_3216915_8 cell shape determining protein, MreB Mrl K03569 - - 1.6e-219 683.0
TH2_k127_3216915_9 TIGRFAM A G-specific adenine glycosylase K03575 - - 1.837e-219 683.0
TH2_k127_3217438_0 Sodium:alanine symporter family K03310 - - 3.146e-291 896.0
TH2_k127_3217438_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009727 533.0
TH2_k127_3217438_2 nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 533.0
TH2_k127_3217438_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000006971 196.0
TH2_k127_3217438_4 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000574 117.0
TH2_k127_3217438_5 Permease MlaE K02066 - - 0.0000000000000000000006496 96.0
TH2_k127_3217438_6 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000001713 70.0
TH2_k127_3217438_7 - - - - 0.000000276 54.0
TH2_k127_3217438_8 DNA-binding transcription factor activity K10680 - - 0.000006704 49.0
TH2_k127_3358023_0 Transglutaminase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 611.0
TH2_k127_3358023_1 domain protein - - - 0.000000000000000000009395 98.0
TH2_k127_3370037_0 Amino acid permease - - - 2.02e-292 904.0
TH2_k127_3370037_1 Rhodanese-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007969 246.0
TH2_k127_3484206_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.359e-230 717.0
TH2_k127_3484206_1 WD40-like Beta Propeller Repeat - - - 6.514e-220 685.0
TH2_k127_3484206_2 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 612.0
TH2_k127_3484206_3 pdz dhr glgf - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 402.0
TH2_k127_3484206_4 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001646 256.0
TH2_k127_3598010_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0 1012.0
TH2_k127_3598010_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.026e-270 833.0
TH2_k127_3598010_2 Bacterial extracellular solute-binding protein K02012 - - 5.689e-208 648.0
TH2_k127_3598010_3 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 2.693e-207 647.0
TH2_k127_3598010_4 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000000000000004531 226.0
TH2_k127_3598010_5 Protein of unknown function (DUF3750) - - - 0.0000000000000000000000000000000000000000000000000001524 185.0
TH2_k127_36390_0 AMP-dependent synthetase - - - 4.33e-303 933.0
TH2_k127_36390_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.359e-288 888.0
TH2_k127_36390_2 PFAM Orn DAP Arg decarboxylase 2 K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 294.0
TH2_k127_36390_3 - - - - 0.00000004781 54.0
TH2_k127_36390_4 - - - - 0.000003752 49.0
TH2_k127_364125_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1041.0
TH2_k127_364125_1 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000145 105.0
TH2_k127_3724521_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1332.0
TH2_k127_3724521_1 Diguanylate cyclase - - - 8.864e-310 955.0
TH2_k127_3724521_2 PFAM aminotransferase, class I K00812 - 2.6.1.1 6.019e-244 757.0
TH2_k127_3724521_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 455.0
TH2_k127_3724521_4 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 351.0
TH2_k127_3724521_5 tRNA rRNA methyltransferase, SpoU K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 284.0
TH2_k127_3724521_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000606 223.0
TH2_k127_3724521_7 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.000000000000000000000000000000000000000000000000007818 181.0
TH2_k127_373639_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1801.0
TH2_k127_373639_1 cytochrome C peroxidase - - - 0.0 1311.0
TH2_k127_373639_10 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 408.0
TH2_k127_373639_11 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 401.0
TH2_k127_373639_12 SMART Diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 319.0
TH2_k127_373639_13 Thioredoxin-like domain K03671,K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 286.0
TH2_k127_373639_14 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002141 240.0
TH2_k127_373639_15 Protein of unknown function (DUF3579) - - - 0.00000000000000000000000000000000000000000000000000000000000009076 214.0
TH2_k127_373639_16 - - - - 0.00000000000000000000000000000000000000000000000000000006836 196.0
TH2_k127_373639_17 MerR HTH family regulatory protein K18997 - - 0.000000000000000000000000000000000000000000000000000003116 191.0
TH2_k127_373639_18 - - - - 0.0000000000000000000000000000000000000000000000000001474 188.0
TH2_k127_373639_19 - - - - 0.0000000000000000000000000000000000003604 141.0
TH2_k127_373639_2 PFAM Multicopper oxidase, type K04753,K08100,K14588 - 1.3.3.5 0.0 1000.0
TH2_k127_373639_20 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000001097 120.0
TH2_k127_373639_22 DDE domain - - - 0.000000000000000006146 85.0
TH2_k127_373639_23 diguanylate cyclase - - - 0.0000000000000001664 80.0
TH2_k127_373639_3 Putative Na+/H+ antiporter - - - 2.763e-261 806.0
TH2_k127_373639_4 PFAM Peptidase S1 S6, chymotrypsin Hap K08070 - 1.3.1.74 5.587e-240 743.0
TH2_k127_373639_5 outer membrane efflux protein K15725 - - 3.481e-233 725.0
TH2_k127_373639_6 Bacterial protein of unknown function (DUF839) K07093 - - 3.757e-227 707.0
TH2_k127_373639_7 Putative aminopeptidase - - - 2.045e-205 642.0
TH2_k127_373639_8 PFAM heat shock protein DnaJ K05516 - - 2.055e-196 613.0
TH2_k127_373639_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 612.0
TH2_k127_3755_0 Cytidylate kinase-like family - - - 0.000000000000000007615 92.0
TH2_k127_3755_1 H subunit K02107 - - 0.00001801 51.0
TH2_k127_3851238_0 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 316.0
TH2_k127_3851238_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000001199 224.0
TH2_k127_3851238_2 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000005673 116.0
TH2_k127_3924651_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0 1710.0
TH2_k127_3924651_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1461.0
TH2_k127_3924651_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0 1130.0
TH2_k127_3924651_3 PFAM Metal-dependent hydrolase HDOD - - - 4.577e-298 919.0
TH2_k127_3924651_4 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 469.0
TH2_k127_3924651_5 Sporulation related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 434.0
TH2_k127_3924651_6 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 392.0
TH2_k127_3924651_7 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 384.0
TH2_k127_3924651_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 304.0
TH2_k127_395921_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0 1169.0
TH2_k127_395921_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 3.086e-259 802.0
TH2_k127_395921_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005382 271.0
TH2_k127_395921_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000000000000000000000000000000000002786 213.0
TH2_k127_395921_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000006658 111.0
TH2_k127_395921_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000001581 83.0
TH2_k127_395921_6 DDE superfamily endonuclease - - - 0.00000000002511 64.0
TH2_k127_395921_7 Winged helix-turn helix - - - 0.0002036 47.0
TH2_k127_3966433_0 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 3.647e-244 755.0
TH2_k127_3966433_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.916e-241 747.0
TH2_k127_3966433_2 Sodium:dicarboxylate symporter family K11102 - - 5.334e-236 733.0
TH2_k127_3966433_3 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 4.203e-205 638.0
TH2_k127_3966433_4 RIO1 family K07178 - 2.7.11.1 0.00000000000000000000000000000000000000002938 153.0
TH2_k127_3968282_0 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 0.0 2021.0
TH2_k127_3968282_1 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 9.744e-306 962.0
TH2_k127_3968282_2 PFAM Peptidyl-prolyl cis-trans isomerase, cyclophilin-type K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 519.0
TH2_k127_3968282_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 357.0
TH2_k127_3968282_4 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000000000000003132 229.0
TH2_k127_3973047_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 6.654e-283 870.0
TH2_k127_3973047_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 480.0
TH2_k127_3973047_2 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 441.0
TH2_k127_3973047_3 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 335.0
TH2_k127_3973047_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000007067 163.0
TH2_k127_4037614_0 PFAM Transposase, IS4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 416.0
TH2_k127_4037614_1 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 322.0
TH2_k127_4037614_2 Clan AA aspartic protease, AF_0612 family - - - 0.0000000000000000000000000000000000000000000006791 169.0
TH2_k127_4037614_3 PIN domain - - - 0.000000000000002926 81.0
TH2_k127_4037614_4 PIN domain - - - 0.0000000001269 64.0
TH2_k127_4049378_0 PFAM secretion protein HlyD - - - 4.319e-199 623.0
TH2_k127_4049378_1 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 601.0
TH2_k127_4049378_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000006551 93.0
TH2_k127_42201_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000006961 127.0
TH2_k127_42201_1 Protein of unknown function (DUF1559) K02456 - - 0.00000001209 65.0
TH2_k127_422509_0 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 393.0
TH2_k127_422509_1 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 372.0
TH2_k127_422509_2 TIGRFAM Methionine sulphoxide reductase B K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 332.0
TH2_k127_422509_3 Protein of unknown function (DUF3617) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000152 239.0
TH2_k127_422509_4 - - - - 0.00000000000000000000000000000000000000000000000000000000003744 207.0
TH2_k127_4258863_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 1.176e-219 684.0
TH2_k127_4258863_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 514.0
TH2_k127_4258863_2 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 467.0
TH2_k127_4258863_3 PFAM Polyketide cyclase dehydrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 315.0
TH2_k127_4258863_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 300.0
TH2_k127_4258863_5 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 295.0
TH2_k127_4258863_6 - - - - 0.000000000000000000000000000000000000000000000000005905 186.0
TH2_k127_4258863_7 Nucleotidyltransferase domain - - - 0.00000000000000000000000000002065 120.0
TH2_k127_4258863_8 PFAM Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000009 100.0
TH2_k127_441256_0 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 414.0
TH2_k127_441256_1 Belongs to the GcvT family K06980 - - 0.0000000000000000005488 89.0
TH2_k127_442309_0 Histidine kinase K03407 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.0 1270.0
TH2_k127_442309_1 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor - - - 8.916e-313 961.0
TH2_k127_442309_10 TIGRFAM Diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 477.0
TH2_k127_442309_11 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 419.0
TH2_k127_442309_12 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 396.0
TH2_k127_442309_13 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 393.0
TH2_k127_442309_14 NlpC/P60 family K13695,K19303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 315.0
TH2_k127_442309_15 PFAM CheW-like protein K03408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 306.0
TH2_k127_442309_16 PFAM Signal transduction response regulator, receiver K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000009696 233.0
TH2_k127_442309_17 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000000000000000000000000000000179 198.0
TH2_k127_442309_18 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337 - - 0.0000000000000000000001289 108.0
TH2_k127_442309_19 PFAM Transposase, IS4-like K07481 - - 0.0000000000000000000002728 98.0
TH2_k127_442309_2 SMART Diguanylate cyclase K13590 - 2.7.7.65 3.285e-305 942.0
TH2_k127_442309_20 - - - - 0.00000000000009991 72.0
TH2_k127_442309_23 - - - - 0.0000002018 53.0
TH2_k127_442309_24 Carbohydrate-selective porin, OprB family - - - 0.0006651 42.0
TH2_k127_442309_3 Sulfatase K01130 - 3.1.6.1 4.033e-280 867.0
TH2_k127_442309_4 Cytochrome c554 and c-prime - - - 4.863e-264 834.0
TH2_k127_442309_5 PFAM Chemotaxis methyl-accepting receptor, signalling K03406,K03776,K05874 - - 1.73e-250 784.0
TH2_k127_442309_6 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 1.598e-216 674.0
TH2_k127_442309_7 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 587.0
TH2_k127_442309_8 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 569.0
TH2_k127_442309_9 Protein of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 578.0
TH2_k127_4474240_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0 1816.0
TH2_k127_4474240_1 ISXO2-like transposase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004565 246.0
TH2_k127_4474240_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.0000000002329 61.0
TH2_k127_4494556_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 575.0
TH2_k127_4494556_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 535.0
TH2_k127_4494556_2 PFAM Copper resistance D K07245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 486.0
TH2_k127_4494556_3 PFAM Copper resistance protein CopC K07156 - - 0.000000000000000000000000000000000000000000000000000000000000000000001179 237.0
TH2_k127_4529664_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1229.0
TH2_k127_4529664_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 1.685e-240 743.0
TH2_k127_4529664_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 285.0
TH2_k127_4537369_0 PFAM Ketopantoate reductase ApbA PanE, C-terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 418.0
TH2_k127_4537369_1 HlyD family secretion protein K02005 - - 0.000000000000000000000000002168 112.0
TH2_k127_455637_0 Cysteine-rich domain - - - 6.917e-296 909.0
TH2_k127_455637_1 Ammonium transporter K03320,K06580 - - 2.876e-275 850.0
TH2_k127_455637_2 CNP1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 309.0
TH2_k127_4563675_0 Hydrogenase formation hypA family K04654 - - 4.924e-243 751.0
TH2_k127_4563675_1 AIR synthase related protein, N-terminal domain K04655 - - 8.009e-220 683.0
TH2_k127_4563675_2 L,D-transpeptidase catalytic domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 608.0
TH2_k127_4563675_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 353.0
TH2_k127_4563675_4 Belongs to the enoyl-CoA hydratase isomerase family K19640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009809 264.0
TH2_k127_4563675_5 Alanine-zipper, major outer membrane lipoprotein K06078 - - 0.00000000000000000000000000000000000000003851 154.0
TH2_k127_4563675_6 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000000000000000000002331 130.0
TH2_k127_4563675_7 PFAM porin, Gram-negative type - - - 0.00000000000000000000000000001431 119.0
TH2_k127_4570315_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1494.0
TH2_k127_4570315_1 HDOD domain - - - 5.409e-249 771.0
TH2_k127_4570315_2 type II secretion system protein E K02670 - - 2.16e-235 729.0
TH2_k127_4570315_3 PFAM Type II secretion system protein E K02669,K12203 - - 9.246e-217 674.0
TH2_k127_4570315_4 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001021 254.0
TH2_k127_4574057_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1065.0
TH2_k127_4574057_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.606e-320 983.0
TH2_k127_4574057_10 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 574.0
TH2_k127_4574057_11 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 553.0
TH2_k127_4574057_12 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 542.0
TH2_k127_4574057_13 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 541.0
TH2_k127_4574057_14 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 534.0
TH2_k127_4574057_15 TolA C-terminal K03646 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 529.0
TH2_k127_4574057_16 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 489.0
TH2_k127_4574057_17 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 459.0
TH2_k127_4574057_18 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 432.0
TH2_k127_4574057_19 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 430.0
TH2_k127_4574057_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.685e-293 900.0
TH2_k127_4574057_20 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 413.0
TH2_k127_4574057_21 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 399.0
TH2_k127_4574057_22 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 400.0
TH2_k127_4574057_23 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009964 373.0
TH2_k127_4574057_24 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 353.0
TH2_k127_4574057_25 transport-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 346.0
TH2_k127_4574057_26 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 343.0
TH2_k127_4574057_27 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 322.0
TH2_k127_4574057_28 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 321.0
TH2_k127_4574057_29 Two component signalling adaptor domain K02659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 318.0
TH2_k127_4574057_3 FAD linked oxidases, C-terminal domain K00102,K03777 - 1.1.2.4,1.1.5.12 1.463e-277 856.0
TH2_k127_4574057_30 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 316.0
TH2_k127_4574057_31 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 305.0
TH2_k127_4574057_32 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 289.0
TH2_k127_4574057_33 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 288.0
TH2_k127_4574057_34 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 281.0
TH2_k127_4574057_35 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001523 273.0
TH2_k127_4574057_36 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008612 267.0
TH2_k127_4574057_37 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002892 260.0
TH2_k127_4574057_38 4-hydroxybenzoyl-CoA thioesterase K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002993 250.0
TH2_k127_4574057_39 Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009835 246.0
TH2_k127_4574057_4 Involved in the TonB-independent uptake of proteins K03641 - - 2.852e-273 842.0
TH2_k127_4574057_40 ATP synthase I chain K02116 - - 0.0000000000000000000000000000000000000000000000000000000000004544 212.0
TH2_k127_4574057_41 - - - - 0.000000000000000000000000000000000000000000000000000000000005689 209.0
TH2_k127_4574057_42 Aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000000001519 204.0
TH2_k127_4574057_43 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000000000000000005192 172.0
TH2_k127_4574057_44 Protein of unknown function (DUF3460) - - - 0.00000000000000000000000000002424 117.0
TH2_k127_4574057_45 - - - - 0.0000000000000000000000005489 105.0
TH2_k127_4574057_46 Protein of unknown function (DUF2970) - - - 0.0000000000000000000003886 96.0
TH2_k127_4574057_47 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000548 68.0
TH2_k127_4574057_48 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000118 62.0
TH2_k127_4574057_49 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000007365 52.0
TH2_k127_4574057_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 4.466e-259 803.0
TH2_k127_4574057_6 Belongs to the thiolase family K00626 - 2.3.1.9 1.542e-239 743.0
TH2_k127_4574057_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 7.036e-212 659.0
TH2_k127_4574057_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 1.592e-205 641.0
TH2_k127_4574057_9 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 574.0
TH2_k127_4582772_0 Domain of unknown function (DUF4139) - - - 1.065e-278 858.0
TH2_k127_4582772_1 PFAM Aminotransferase, class V K04487 - 2.8.1.7 3.067e-227 706.0
TH2_k127_4582772_2 response regulator containing a CheY-like receiver - - - 3.825e-221 688.0
TH2_k127_4582772_3 fatty acid desaturase - - - 1.232e-218 679.0
TH2_k127_4582772_4 VanZ like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 609.0
TH2_k127_4582772_5 PFAM Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 476.0
TH2_k127_4582772_6 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 474.0
TH2_k127_4582772_7 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 310.0
TH2_k127_4582772_8 Histidine triad (HIT) protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 280.0
TH2_k127_4583174_0 Bacterial regulatory helix-turn-helix protein, lysR family K03576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 569.0
TH2_k127_4583174_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 533.0
TH2_k127_4583174_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 286.0
TH2_k127_4583174_3 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002188 275.0
TH2_k127_4583174_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000002763 220.0
TH2_k127_4583174_5 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000000000000000003936 214.0
TH2_k127_4583174_6 SIR2-like domain - - - 0.00000000000000000000000000000000000000000001748 163.0
TH2_k127_4583174_7 NAD+ binding - - - 0.000000131 54.0
TH2_k127_4584729_0 Multicopper oxidase type - - - 0.0 1355.0
TH2_k127_4584729_1 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 415.0
TH2_k127_4584729_2 - - - - 0.00000000000003782 73.0
TH2_k127_4584729_3 - - - - 0.0000001901 54.0
TH2_k127_4596588_0 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 0.0 1035.0
TH2_k127_4596588_1 Metal-dependent hydrolase HDOD - - - 1.368e-262 813.0
TH2_k127_4596588_10 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 293.0
TH2_k127_4596588_11 Domain of unknown function (DUF4156) - - - 0.000000000000000000000000000000000000000000000000000000000000007101 218.0
TH2_k127_4596588_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000001594 216.0
TH2_k127_4596588_14 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000001048 179.0
TH2_k127_4596588_15 manually curated - - - 0.00000000000003256 73.0
TH2_k127_4596588_16 - - - - 0.0000000000001675 72.0
TH2_k127_4596588_17 - - - - 0.0009642 46.0
TH2_k127_4596588_2 CHAD - - - 2.321e-260 809.0
TH2_k127_4596588_3 Belongs to the UPF0176 family K07146 - - 2.303e-195 610.0
TH2_k127_4596588_4 E3 Ubiquitin ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 574.0
TH2_k127_4596588_5 TIGRFAM Polyphosphate nucleotide phosphotransferase, PPK2 K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 471.0
TH2_k127_4596588_6 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 447.0
TH2_k127_4596588_7 SMART HTH transcriptional regulator, Crp K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 406.0
TH2_k127_4596588_8 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 366.0
TH2_k127_4597694_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1751.0
TH2_k127_4597694_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1440.0
TH2_k127_4597694_10 Dodecin K09165 - - 0.0000000000000000000000000000000003748 132.0
TH2_k127_4597694_11 Protein of unknown function (DUF3622) - - - 0.00000000000000000000000000001736 119.0
TH2_k127_4597694_2 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 3.239e-237 736.0
TH2_k127_4597694_3 DNA polymerase III (Delta subunit) K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 605.0
TH2_k127_4597694_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 599.0
TH2_k127_4597694_5 PFAM Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 458.0
TH2_k127_4597694_6 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001368 272.0
TH2_k127_4597694_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006866 248.0
TH2_k127_4597694_8 ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000003222 224.0
TH2_k127_4597694_9 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001365 221.0
TH2_k127_4601692_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 2.271e-272 843.0
TH2_k127_4601692_1 Carboxysome Shell Carbonic Anhydrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 600.0
TH2_k127_4601692_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 496.0
TH2_k127_4601692_3 Phosphorylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 354.0
TH2_k127_4619639_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1281.0
TH2_k127_4619639_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0 1119.0
TH2_k127_4619639_10 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 340.0
TH2_k127_4619639_11 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000005001 244.0
TH2_k127_4619639_12 - - - - 0.000000000000000000000000000000000000000000000000000000001782 202.0
TH2_k127_4619639_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000000000000000000000004097 169.0
TH2_k127_4619639_14 Protein of unknown function DUF86 - - - 0.000000000000000000000000000001458 126.0
TH2_k127_4619639_16 positive regulation of growth K07746 - - 0.0000000000000000000000000234 110.0
TH2_k127_4619639_17 nucleotidyltransferase activity - - - 0.0000000000000006559 81.0
TH2_k127_4619639_18 nucleotidyltransferase activity - - - 0.00000000002317 67.0
TH2_k127_4619639_19 - - - - 0.0000000001983 63.0
TH2_k127_4619639_2 argininosuccinate lyase K01755 - 4.3.2.1 5.992e-298 919.0
TH2_k127_4619639_20 Transposase IS200 like - - - 0.00000005854 55.0
TH2_k127_4619639_22 Nucleotidyltransferase domain - - - 0.00001612 52.0
TH2_k127_4619639_23 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0001006 46.0
TH2_k127_4619639_25 Transposase IS200 like - - - 0.000729 44.0
TH2_k127_4619639_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 1.343e-265 819.0
TH2_k127_4619639_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 4.353e-250 774.0
TH2_k127_4619639_5 diguanylate cyclase K02488 - 2.7.7.65 1.11e-236 736.0
TH2_k127_4619639_6 Fructosamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 540.0
TH2_k127_4619639_7 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 533.0
TH2_k127_4619639_8 membrane K08994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 497.0
TH2_k127_4619639_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 365.0
TH2_k127_4656315_0 Radical SAM superfamily K04069 - 1.97.1.4 1.313e-242 750.0
TH2_k127_4656315_1 Lipase (class 3) - - - 2.913e-240 745.0
TH2_k127_4656315_2 PFAM UPF0103 Mediator of ErbB2-driven cell motility K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 492.0
TH2_k127_4656315_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 435.0
TH2_k127_4656315_4 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 368.0
TH2_k127_4656315_5 PFAM AMMECR1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001325 220.0
TH2_k127_4656315_6 - - - - 0.000000000000000000000007467 102.0
TH2_k127_4658080_0 ABC transporter transmembrane region K12536 - - 0.0 1036.0
TH2_k127_4658080_1 TIGRFAM Type I secretion membrane fusion protein, HlyD K02022,K12537,K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 333.0
TH2_k127_4664452_0 ABC transporter C-terminal domain K15738 - - 0.0 1219.0
TH2_k127_4664452_1 Multicopper oxidase type - - - 0.0 1106.0
TH2_k127_4664452_10 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000002908 209.0
TH2_k127_4664452_11 Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000007877 207.0
TH2_k127_4664452_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000001127 147.0
TH2_k127_4664452_13 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000001143 154.0
TH2_k127_4664452_14 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000006322 113.0
TH2_k127_4664452_15 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000002111 76.0
TH2_k127_4664452_16 PFAM transposase, IS4 family protein - - - 0.00000000000003306 78.0
TH2_k127_4664452_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 3.692e-206 644.0
TH2_k127_4664452_3 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 533.0
TH2_k127_4664452_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 466.0
TH2_k127_4664452_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 410.0
TH2_k127_4664452_6 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 411.0
TH2_k127_4664452_7 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 371.0
TH2_k127_4664452_8 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 310.0
TH2_k127_4664452_9 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001304 273.0
TH2_k127_4680747_0 Mechanosensitive ion channel K05802,K22051 - - 0.0 1582.0
TH2_k127_4680747_1 McrBC 5-methylcytosine restriction system component K19147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 423.0
TH2_k127_4680747_2 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000004433 226.0
TH2_k127_4680747_3 - - - - 0.000000000000000000000000000000000000000002488 159.0
TH2_k127_4680747_4 Putative transposase - - - 0.000000000000000000000000000000000000000105 154.0
TH2_k127_4680747_5 PFAM Integrase, catalytic core K07497 - - 0.0000000000000000002912 89.0
TH2_k127_4715084_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.0 1139.0
TH2_k127_4715084_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1118.0
TH2_k127_4715084_10 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 2.878e-211 658.0
TH2_k127_4715084_11 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 556.0
TH2_k127_4715084_12 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 550.0
TH2_k127_4715084_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 502.0
TH2_k127_4715084_14 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 428.0
TH2_k127_4715084_15 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 385.0
TH2_k127_4715084_16 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 312.0
TH2_k127_4715084_17 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 300.0
TH2_k127_4715084_18 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003089 251.0
TH2_k127_4715084_19 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001018 223.0
TH2_k127_4715084_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0 1072.0
TH2_k127_4715084_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000001702 216.0
TH2_k127_4715084_21 - - - - 0.000000000000000000000000000000000000000007688 156.0
TH2_k127_4715084_22 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000000009582 154.0
TH2_k127_4715084_23 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000000000001451 153.0
TH2_k127_4715084_24 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000000000000000000006273 116.0
TH2_k127_4715084_25 PFAM transposase, IS4 family protein K07481 - - 0.0006215 44.0
TH2_k127_4715084_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0 1003.0
TH2_k127_4715084_4 modulator of DNA gyrase K03568 - - 9.398e-311 954.0
TH2_k127_4715084_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 6.527e-281 864.0
TH2_k127_4715084_6 HflC and HflK could encode or regulate a protease K04088 - - 5.637e-240 743.0
TH2_k127_4715084_7 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 4.961e-223 695.0
TH2_k127_4715084_8 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 3.169e-213 666.0
TH2_k127_4715084_9 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 3.496e-213 664.0
TH2_k127_4718265_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1349.0
TH2_k127_4718265_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 390.0
TH2_k127_4728070_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 2293.0
TH2_k127_4728070_1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381,K00392 - 1.8.1.2,1.8.7.1 0.0 1162.0
TH2_k127_4728070_10 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 518.0
TH2_k127_4728070_11 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 492.0
TH2_k127_4728070_12 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 482.0
TH2_k127_4728070_13 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 428.0
TH2_k127_4728070_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 347.0
TH2_k127_4728070_15 alpha-ribazole phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 319.0
TH2_k127_4728070_16 Predicted small integral membrane protein (DUF2165) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 310.0
TH2_k127_4728070_17 Bacterial protein of unknown function (DUF934) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003087 275.0
TH2_k127_4728070_18 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007538 261.0
TH2_k127_4728070_19 Protein of unknown function (DUF3293) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009511 249.0
TH2_k127_4728070_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 3.008e-289 889.0
TH2_k127_4728070_20 4TM region of pyridine nucleotide transhydrogenase, mitoch K00322,K00324 - 1.6.1.1,1.6.1.2 0.0000000000000000000000000000000000000000000000000000000023 201.0
TH2_k127_4728070_21 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000007457 194.0
TH2_k127_4728070_22 - - - - 0.000000000000000000000000000000000000000000004228 163.0
TH2_k127_4728070_23 PFAM Nucleotidyltransferase - - - 0.000000000000000000000000000000000000003554 149.0
TH2_k127_4728070_24 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.000000000000000000000000000000000000003644 147.0
TH2_k127_4728070_25 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000000004254 143.0
TH2_k127_4728070_26 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000002972 136.0
TH2_k127_4728070_28 TIGRFAM Nucleotidyltransferase substrate binding protein, HI0074 - - - 0.00000000000000000000000000000001105 128.0
TH2_k127_4728070_29 - - - - 0.0000000000000000000000002681 105.0
TH2_k127_4728070_3 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 2.693e-269 829.0
TH2_k127_4728070_30 NnrS protein K07234 - - 0.0000000000000000008738 85.0
TH2_k127_4728070_33 nucleotide-binding Protein - - - 0.000000000001937 69.0
TH2_k127_4728070_34 TIR domain - - - 0.00000234 50.0
TH2_k127_4728070_35 TIGRFAM Nucleotidyltransferase substrate binding protein, HI0074 - - - 0.0000879 45.0
TH2_k127_4728070_4 PFAM Alanine dehydrogenase PNT K00324 - 1.6.1.2 2.008e-224 698.0
TH2_k127_4728070_5 Bacterial regulatory helix-turn-helix protein, lysR family K13634 - - 2.869e-202 631.0
TH2_k127_4728070_6 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 2.256e-196 613.0
TH2_k127_4728070_7 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 1.993e-195 611.0
TH2_k127_4728070_8 adenylyltransferase, small subunit K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 595.0
TH2_k127_4728070_9 Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 532.0
TH2_k127_4740280_0 Enoyl-CoA hydratase isomerase K19640 - - 0.0 1102.0
TH2_k127_4740280_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 281.0
TH2_k127_4740280_2 tigrfam pep-cterm - - - 0.0000000000000000000000000000000002458 139.0
TH2_k127_4740280_3 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.000000003673 57.0
TH2_k127_4740975_0 DinB superfamily - - - 0.0 1436.0
TH2_k127_4740975_1 Sulfatase K01130 - 3.1.6.1 5.735e-298 922.0
TH2_k127_4740975_10 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000007061 201.0
TH2_k127_4740975_11 - - - - 0.00000000000000000000000000000000000000000000000000003145 196.0
TH2_k127_4740975_12 - - - - 0.00000000000000000000000000000000000002637 150.0
TH2_k127_4740975_13 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000001208 139.0
TH2_k127_4740975_14 Lysozyme inhibitor LprI - - - 0.00000000000000000000001008 102.0
TH2_k127_4740975_2 PFAM aminotransferase, class I K00842,K14155 - 4.4.1.8 1.701e-240 746.0
TH2_k127_4740975_3 ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 508.0
TH2_k127_4740975_4 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 444.0
TH2_k127_4740975_5 Predicted periplasmic protein (DUF2092) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 355.0
TH2_k127_4740975_6 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 308.0
TH2_k127_4740975_7 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 296.0
TH2_k127_4740975_8 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000004009 261.0
TH2_k127_4740975_9 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000001446 214.0
TH2_k127_4791880_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 1.1e-311 958.0
TH2_k127_4791880_1 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 552.0
TH2_k127_4791880_3 PFAM Transposase, IS4-like K07481 - - 0.00000000000003324 72.0
TH2_k127_4808173_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 575.0
TH2_k127_4808173_1 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 383.0
TH2_k127_4808173_2 transporter antisigma-factor antagonist STAS K07122 - - 0.00000000000000000000000000000000000000000000000000000005757 196.0
TH2_k127_4808173_3 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000007098 157.0
TH2_k127_4832827_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 581.0
TH2_k127_4832827_1 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 359.0
TH2_k127_4832827_2 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 355.0
TH2_k127_4832827_3 Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 310.0
TH2_k127_4832827_4 PFAM Blue (type 1) copper domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 294.0
TH2_k127_4832827_5 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000000000000000000000000000001163 228.0
TH2_k127_4832827_6 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000004096 196.0
TH2_k127_4832827_7 - - - - 0.00000000000000000000000000000000000000000001216 166.0
TH2_k127_4852250_0 TIGRFAM TonB-dependent vitamin B12 receptor K16092 - - 0.0 1179.0
TH2_k127_4852250_1 phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 423.0
TH2_k127_4852250_10 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000004288 96.0
TH2_k127_4852250_11 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase, WcaJ K03606 - - 0.000000000000000000007449 91.0
TH2_k127_4852250_2 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 393.0
TH2_k127_4852250_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 365.0
TH2_k127_4852250_4 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007529 267.0
TH2_k127_4852250_5 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000000000016 201.0
TH2_k127_4852250_6 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000009921 138.0
TH2_k127_4852250_7 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000001255 126.0
TH2_k127_4852250_8 Transglutaminase-like superfamily - - - 0.0000000000000000000000003394 107.0
TH2_k127_4852250_9 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000001711 100.0
TH2_k127_4864951_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 3.52e-248 767.0
TH2_k127_4864951_1 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 1.584e-210 656.0
TH2_k127_4864951_10 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 282.0
TH2_k127_4864951_11 DNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005151 242.0
TH2_k127_4864951_12 TIGRFAM Addiction module killer protein, HI1419 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002914 229.0
TH2_k127_4864951_13 D5 N terminal like K06919 - - 0.00000000000000000000000000000000000000000000000000000000000000001548 233.0
TH2_k127_4864951_14 addiction module antidote protein - - - 0.0000000000000000000000000000000000000000000000000000001948 194.0
TH2_k127_4864951_15 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000000000000000000000000000000008394 182.0
TH2_k127_4864951_16 - - - - 0.00000000000000000000004431 99.0
TH2_k127_4864951_17 Helix-turn-helix K21498 - - 0.0000000000000000004618 88.0
TH2_k127_4864951_18 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000006559 81.0
TH2_k127_4864951_19 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000002477 63.0
TH2_k127_4864951_2 Belongs to the 'phage' integrase family - - - 8.74e-206 647.0
TH2_k127_4864951_21 PFAM Integrase, catalytic core K07497 - - 0.0000171 48.0
TH2_k127_4864951_3 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 588.0
TH2_k127_4864951_4 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 489.0
TH2_k127_4864951_5 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 463.0
TH2_k127_4864951_6 N-acetylmuramoyl-L-alanine amidase (Family 2) K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 370.0
TH2_k127_4864951_7 'signal transduction protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 359.0
TH2_k127_4864951_8 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 334.0
TH2_k127_4864951_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 300.0
TH2_k127_489654_0 Domain of Unknown Function (DUF748) - - - 0.0 1820.0
TH2_k127_489654_1 PFAM Copper resistance D K07245 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 508.0
TH2_k127_489654_2 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 298.0
TH2_k127_489654_3 Protein of unknown function (DUF454) K09790 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 281.0
TH2_k127_489654_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000007042 236.0
TH2_k127_489654_5 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000103 116.0
TH2_k127_4903510_0 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000002835 229.0
TH2_k127_4903510_1 Phage integrase family - - - 0.000000000000000000000000000000000000001787 161.0
TH2_k127_4903510_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000004905 82.0
TH2_k127_4984312_0 Putative peptidoglycan binding domain K21470 - - 4.154e-297 917.0
TH2_k127_4984312_1 PFAM Peptidase M18 K01267 - 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 434.0
TH2_k127_4984312_2 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 380.0
TH2_k127_4984312_3 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 317.0
TH2_k127_4984312_4 - - - - 0.0000000000000000000000000000000000000000000000000000004639 196.0
TH2_k127_4984312_5 - - - - 0.0000000000000000000000000000000000000000000000002251 186.0
TH2_k127_4984312_6 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.0000000007151 59.0
TH2_k127_501153_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0 1192.0
TH2_k127_501153_1 PFAM Lytic transglycosylase-like, catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 430.0
TH2_k127_501153_2 PFAM Peptidyl-prolyl cis-trans isomerase, cyclophilin-type K03767 - 5.2.1.8 0.000000000000002111 76.0
TH2_k127_5092347_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 7.411e-274 842.0
TH2_k127_5092347_1 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 3.604e-200 624.0
TH2_k127_5092347_2 endonuclease exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 518.0
TH2_k127_5092347_3 - - - - 0.0000000001163 64.0
TH2_k127_5092347_4 - - - - 0.000000006705 57.0
TH2_k127_5112882_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1520.0
TH2_k127_5112882_1 Regulator of K conductance, C-terminal - - - 0.0 1100.0
TH2_k127_5112882_11 - - - - 0.000007581 49.0
TH2_k127_5112882_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0 1033.0
TH2_k127_5112882_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.612e-272 839.0
TH2_k127_5112882_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.105e-245 762.0
TH2_k127_5112882_5 Belongs to the RNase T2 family K01166 - 3.1.27.1 2.612e-202 633.0
TH2_k127_5112882_6 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 480.0
TH2_k127_5112882_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 416.0
TH2_k127_5112882_8 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 415.0
TH2_k127_5112882_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000000000001858 183.0
TH2_k127_524482_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.096e-298 916.0
TH2_k127_524482_1 synthetase, class II (G H P K01892 - 6.1.1.21 1.594e-264 816.0
TH2_k127_524482_10 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004205 261.0
TH2_k127_524482_11 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004269 255.0
TH2_k127_524482_12 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000000000000000003571 128.0
TH2_k127_524482_13 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000007693 63.0
TH2_k127_524482_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 7.795e-263 810.0
TH2_k127_524482_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 1.632e-230 717.0
TH2_k127_524482_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 6.294e-224 695.0
TH2_k127_524482_5 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 605.0
TH2_k127_524482_6 TIGRFAM Pilus biogenesis stability type IV, PilW K02656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 467.0
TH2_k127_524482_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 439.0
TH2_k127_524482_8 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 401.0
TH2_k127_524482_9 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001915 263.0
TH2_k127_5355026_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2696.0
TH2_k127_5355026_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2642.0
TH2_k127_5355026_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 419.0
TH2_k127_5355026_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 355.0
TH2_k127_5355026_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 312.0
TH2_k127_5355026_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000076 279.0
TH2_k127_5355026_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000000000125 208.0
TH2_k127_5355026_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000000000000000000000000000000000000000000000002958 200.0
TH2_k127_5355026_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000005157 80.0
TH2_k127_5355026_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000002578 49.0
TH2_k127_5378888_0 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 506.0
TH2_k127_5378888_1 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 405.0
TH2_k127_5378888_2 PIN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000514 258.0
TH2_k127_5378888_3 PFAM MgtC SapB transporter - - - 0.0000000000000000000133 91.0
TH2_k127_5378888_4 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00002705 49.0
TH2_k127_5397784_0 Protein of unknown function (DUF3570) - - - 0.0 1437.0
TH2_k127_5397784_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 570.0
TH2_k127_5397784_2 Domain of unknown function (DUF4266) - - - 0.000000000000000000000000001208 113.0
TH2_k127_5397784_3 Redoxin domain protein - - - 0.00000000000000003191 80.0
TH2_k127_5406144_0 von Willebrand factor, type A K02448 - - 0.0 1215.0
TH2_k127_5406144_1 Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 1.277e-290 893.0
TH2_k127_5406144_10 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 346.0
TH2_k127_5406144_11 Cytochrome c K02305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 309.0
TH2_k127_5406144_12 Phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000000000000002218 155.0
TH2_k127_5406144_13 - - - - 0.000000000000000000000000000000000007505 138.0
TH2_k127_5406144_14 - - - - 0.0000000000000000000000000000001501 124.0
TH2_k127_5406144_15 - - - - 0.0000000000000000000000001738 106.0
TH2_k127_5406144_16 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000009719 97.0
TH2_k127_5406144_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.555e-273 844.0
TH2_k127_5406144_3 SMART Diguanylate phosphodiesterase - - - 1.335e-271 846.0
TH2_k127_5406144_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 1.927e-254 787.0
TH2_k127_5406144_5 MacB-like periplasmic core domain K02004 - - 7.084e-234 726.0
TH2_k127_5406144_6 MacB-like periplasmic core domain K02004 - - 2.077e-233 724.0
TH2_k127_5406144_7 PFAM Endonuclease exonuclease phosphatase K06896 - 3.1.3.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 577.0
TH2_k127_5406144_8 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 531.0
TH2_k127_5406144_9 pfam abc K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 354.0
TH2_k127_5448878_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1146.0
TH2_k127_5448878_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 4.314e-290 893.0
TH2_k127_5448878_10 MucB/RseB C-terminal domain K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 424.0
TH2_k127_5448878_11 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 327.0
TH2_k127_5448878_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 302.0
TH2_k127_5448878_13 CreA protein K05805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 302.0
TH2_k127_5448878_14 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000001303 242.0
TH2_k127_5448878_15 Domain of unknown function (DUF4845) - - - 0.0000000000000000000000000000000000000000000000000000000002326 204.0
TH2_k127_5448878_16 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000004495 128.0
TH2_k127_5448878_17 Glutaredoxin-like domain (DUF836) K00384 - 1.8.1.9 0.000000000000000000000005385 104.0
TH2_k127_5448878_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 1.989e-289 891.0
TH2_k127_5448878_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 3.093e-267 824.0
TH2_k127_5448878_4 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 4.743e-223 692.0
TH2_k127_5448878_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 563.0
TH2_k127_5448878_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 555.0
TH2_k127_5448878_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 552.0
TH2_k127_5448878_8 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 447.0
TH2_k127_5448878_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 447.0
TH2_k127_5531337_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.0 1317.0
TH2_k127_5531337_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 3.306e-318 975.0
TH2_k127_5531337_10 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 577.0
TH2_k127_5531337_11 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 571.0
TH2_k127_5531337_12 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 545.0
TH2_k127_5531337_13 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 487.0
TH2_k127_5531337_14 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 399.0
TH2_k127_5531337_15 PEP-CTERM motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 386.0
TH2_k127_5531337_16 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 378.0
TH2_k127_5531337_17 oxidoreductase DsbE K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 360.0
TH2_k127_5531337_18 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 307.0
TH2_k127_5531337_19 PFAM Alkyl hydroperoxide reductase K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 297.0
TH2_k127_5531337_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.054e-284 877.0
TH2_k127_5531337_20 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003194 277.0
TH2_k127_5531337_21 Outer membrane lipoprotein Slp family K07285 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001885 277.0
TH2_k127_5531337_22 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000462 265.0
TH2_k127_5531337_23 ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000002086 250.0
TH2_k127_5531337_24 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002672 244.0
TH2_k127_5531337_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001017 226.0
TH2_k127_5531337_26 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000000000003675 191.0
TH2_k127_5531337_27 - - - - 0.00000000000000000000000000000000000001491 144.0
TH2_k127_5531337_28 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000000000008281 70.0
TH2_k127_5531337_29 Histidine kinase K07680,K07778,K11617,K14988 - 2.7.13.3 0.000000003503 60.0
TH2_k127_5531337_3 Na H antiporter NhaC K03315 - - 2.391e-274 848.0
TH2_k127_5531337_4 MFS_1 like family - - - 1.62e-256 792.0
TH2_k127_5531337_5 Tetratricopeptide repeat K02200 - - 1.691e-247 768.0
TH2_k127_5531337_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 8.431e-235 728.0
TH2_k127_5531337_7 alcohol dehydrogenase K00001 - 1.1.1.1 3.129e-216 676.0
TH2_k127_5531337_8 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 610.0
TH2_k127_5531337_9 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008449 590.0
TH2_k127_5576295_0 Protein of unknown function (DUF3494) - - - 0.000000000000000000000000000000000000000001962 181.0
TH2_k127_5576295_1 Right handed beta helix region - - - 0.000000000000000000004877 111.0
TH2_k127_5576295_2 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000001928 91.0
TH2_k127_5576295_3 self proteolysis K04771 - 3.4.21.107 0.00000002906 68.0
TH2_k127_5600545_0 SNARE associated Golgi protein - - - 0.0 1347.0
TH2_k127_5600545_1 AMP-binding enzyme C-terminal domain K00666 - - 4.612e-260 811.0
TH2_k127_5600545_2 Radical SAM superfamily - - - 8.102e-205 638.0
TH2_k127_5600545_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 4.466e-194 614.0
TH2_k127_5600545_4 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 543.0
TH2_k127_5600545_5 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 530.0
TH2_k127_5600545_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 494.0
TH2_k127_5600545_7 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 397.0
TH2_k127_5605019_0 PFAM Rieske 2Fe-2S K00499 - 1.14.15.7 3.024e-254 783.0
TH2_k127_5605019_1 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 555.0
TH2_k127_5605019_10 PFAM Transposase, IS4-like - - - 0.00000000000000000006047 90.0
TH2_k127_5605019_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 492.0
TH2_k127_5605019_3 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 445.0
TH2_k127_5605019_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 310.0
TH2_k127_5605019_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 281.0
TH2_k127_5605019_6 SpoIIAA-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005414 246.0
TH2_k127_5605019_7 PFAM Invasion gene expression up-regulator, SirB - - - 0.00000000000000000000000000000000000000000000000000000000000001484 218.0
TH2_k127_5605019_8 Tetratricopeptide repeat - - - 0.000000000000000000000002727 110.0
TH2_k127_5605019_9 Tetratricopeptide repeat - - - 0.0000000000000000000004869 104.0
TH2_k127_5617516_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 2.818e-254 788.0
TH2_k127_5617516_1 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 4.194e-221 688.0
TH2_k127_5617516_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 391.0
TH2_k127_5617516_3 TIGRFAM Methionine sulphoxide reductase B K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 333.0
TH2_k127_5617516_4 - - - - 0.00000000000000000000000001519 109.0
TH2_k127_5617516_5 - - - - 0.0000000000000000000000111 100.0
TH2_k127_5617516_7 - - - - 0.0000000000007462 70.0
TH2_k127_5617516_8 Transposase DDE domain - - - 0.0000000000008772 67.0
TH2_k127_5617516_9 Pfam Transposase - - - 0.00008326 45.0
TH2_k127_562201_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.0 1240.0
TH2_k127_562201_1 Mediates influx of magnesium ions K03284 - - 7.576e-224 695.0
TH2_k127_562201_10 - - - - 0.0000000000000003992 79.0
TH2_k127_562201_12 Cytidylyltransferase-like - - - 0.000003356 49.0
TH2_k127_562201_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 2.304e-217 676.0
TH2_k127_562201_3 adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 603.0
TH2_k127_562201_4 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 604.0
TH2_k127_562201_5 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 573.0
TH2_k127_562201_6 Protein of unknown function VcgC/VcgE (DUF2780) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 303.0
TH2_k127_562201_7 - - - - 0.000000000000000000000000000000000006016 136.0
TH2_k127_562201_8 Insecticidal toxin complex protein TcaC - - - 0.0000000000000000000000000000001678 131.0
TH2_k127_562201_9 Phosphate-starvation-inducible E - - - 0.00000000000000000005365 91.0
TH2_k127_5633003_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 426.0
TH2_k127_5633003_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000006161 116.0
TH2_k127_5633822_0 PFAM Major facilitator superfamily - - - 2.303e-253 784.0
TH2_k127_5633822_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 4.185e-222 691.0
TH2_k127_5633822_2 Peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 485.0
TH2_k127_5633822_3 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 356.0
TH2_k127_5633822_4 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003701 265.0
TH2_k127_5633822_5 YCII-related domain K09780 - - 0.0000000000000000000000000000000000000000000000002363 177.0
TH2_k127_5640700_0 PFAM Aminoacyl-tRNA synthetase, class Ib K01867 - 6.1.1.2 2.045e-267 823.0
TH2_k127_5640700_1 NnrS protein K07234 - - 2.771e-258 797.0
TH2_k127_5640700_10 Multicopper oxidase - - - 0.0000000000000000000000000000008052 123.0
TH2_k127_5640700_11 response regulator - - - 0.00000000000000003745 81.0
TH2_k127_5640700_12 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00006318 45.0
TH2_k127_5640700_2 PFAM PHP C-terminal K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 579.0
TH2_k127_5640700_3 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 536.0
TH2_k127_5640700_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 459.0
TH2_k127_5640700_5 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 428.0
TH2_k127_5640700_6 Signal transduction response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 426.0
TH2_k127_5640700_7 TIGRFAM Sua5 YciO YrdC YwlC family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 305.0
TH2_k127_5640700_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001264 256.0
TH2_k127_5640700_9 tigrfam pep-cterm - - - 0.00000000000000000000000000000001752 131.0
TH2_k127_5642560_0 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000000000000000000001886 202.0
TH2_k127_5643095_0 Pfam:N_methyl_2 - - - 0.0001753 53.0
TH2_k127_5643095_1 Prokaryotic N-terminal methylation motif - - - 0.0006493 49.0
TH2_k127_5666684_0 Cobalamin synthesis protein cobW C-terminal domain - - - 7.463e-252 778.0
TH2_k127_5666684_1 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000002342 202.0
TH2_k127_5682775_0 The M ring may be actively involved in energy transduction K02409 - - 0.0 1004.0
TH2_k127_5682775_1 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 6.536e-294 903.0
TH2_k127_5682775_2 Flagellar hook-length control K02414 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 530.0
TH2_k127_5682775_3 Flagellar motor switch K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 454.0
TH2_k127_5682775_4 flagellar assembly protein FliH K02411 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 405.0
TH2_k127_5682775_5 Flagellar FliJ protein K02413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003658 260.0
TH2_k127_5682775_6 ISXO2-like transposase domain - - - 0.00000003307 55.0
TH2_k127_5683079_0 alpha beta - - - 3.337e-271 836.0
TH2_k127_5683079_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005113 249.0
TH2_k127_5683079_2 Protein of unknown function (DUF3465) - - - 0.0000000118 59.0
TH2_k127_5715047_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1661.0
TH2_k127_5715047_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1380.0
TH2_k127_5715047_10 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 3.146e-194 606.0
TH2_k127_5715047_11 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 530.0
TH2_k127_5715047_12 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 505.0
TH2_k127_5715047_13 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 329.0
TH2_k127_5715047_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 301.0
TH2_k127_5715047_15 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 289.0
TH2_k127_5715047_16 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001303 242.0
TH2_k127_5715047_17 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000006736 80.0
TH2_k127_5715047_2 heme binding - - - 7.342e-309 953.0
TH2_k127_5715047_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 4.594e-265 816.0
TH2_k127_5715047_4 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 3.895e-244 756.0
TH2_k127_5715047_5 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 3.002e-240 744.0
TH2_k127_5715047_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 3.48e-232 720.0
TH2_k127_5715047_7 PFAM Peptidase S11, D-alanyl-D-alanine carboxypeptidase A K01286,K07258 - 3.4.16.4 1.609e-222 694.0
TH2_k127_5715047_8 NeuB family K03856 - 2.5.1.54 5.289e-217 674.0
TH2_k127_5715047_9 Prephenate dehydratase K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 7.82e-211 657.0
TH2_k127_5715738_0 Nickel-dependent hydrogenase K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 1.057e-219 683.0
TH2_k127_5715738_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 8.102e-198 617.0
TH2_k127_5715738_2 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 604.0
TH2_k127_5715738_3 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 329.0
TH2_k127_5715738_4 Protein of unknown function (DUF2905) - - - 0.00000000000000000000000000000000004024 134.0
TH2_k127_5715738_5 - - - - 0.000000000000000007451 85.0
TH2_k127_5718739_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0 1011.0
TH2_k127_5718739_1 Beta-lactamase enzyme family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 501.0
TH2_k127_5718739_2 - - - - 0.0000000000000000000000000000000000000005419 148.0
TH2_k127_5740184_0 Pfam:N_methyl_2 - - - 0.00000000000000000000000000000000000001998 155.0
TH2_k127_5740184_1 - - - - 0.0000000000000000000003934 100.0
TH2_k127_5740184_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000003577 86.0
TH2_k127_5740184_3 - - - - 0.0000002252 56.0
TH2_k127_5761126_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 365.0
TH2_k127_5761126_1 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007696 265.0
TH2_k127_5804831_0 helicase - - - 0.0 1778.0
TH2_k127_5804831_1 Type III K01156 - 3.1.21.5 0.0 1523.0
TH2_k127_5804831_10 Relaxase mobilization nuclease family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 499.0
TH2_k127_5804831_11 Conjugal transfer protein K20532 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 451.0
TH2_k127_5804831_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 444.0
TH2_k127_5804831_13 PFAM TrbL VirB6 plasmid conjugal transfer protein K07344 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 404.0
TH2_k127_5804831_14 VirB8 protein K20531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
TH2_k127_5804831_15 conjugal transfer protein TraL - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 354.0
TH2_k127_5804831_16 TRANSFER protein K20266 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 329.0
TH2_k127_5804831_17 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 292.0
TH2_k127_5804831_18 Domain of unknown function (DUF4391) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 286.0
TH2_k127_5804831_19 Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001812 271.0
TH2_k127_5804831_2 PFAM CagE, TrbE, VirB component of type IV transporter system K20530 - - 0.0 1298.0
TH2_k127_5804831_20 - K07341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005886 259.0
TH2_k127_5804831_21 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009447 281.0
TH2_k127_5804831_22 Lytic transglycosylase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008381 250.0
TH2_k127_5804831_23 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000001089 246.0
TH2_k127_5804831_24 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000004135 242.0
TH2_k127_5804831_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005058 241.0
TH2_k127_5804831_26 - - - - 0.000000000000000000000000000000000000000000000000000000000001323 211.0
TH2_k127_5804831_27 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000000000000000000399 188.0
TH2_k127_5804831_28 VirC1 protein K03496 - - 0.0000000000000000000000000000000000000000000000002494 183.0
TH2_k127_5804831_29 TrbC/VIRB2 family K20528 - - 0.000000000000000000000000000000000000008724 150.0
TH2_k127_5804831_3 Domain of unknown function (DUF1738) - - - 0.0 1092.0
TH2_k127_5804831_30 PIN domain - - - 0.0000000000000000000000000000000000000324 147.0
TH2_k127_5804831_31 PFAM Conjugal transfer TrbD family protein K20529 - - 0.0000000000000000000000000000000000001032 143.0
TH2_k127_5804831_33 - - - - 0.00000000000000000000000000000005825 128.0
TH2_k127_5804831_34 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000001617 127.0
TH2_k127_5804831_35 - - - - 0.00000000000000000000000000006781 120.0
TH2_k127_5804831_36 PFAM Conjugal transfer, TrbH - - - 0.00000000000000000000000005046 113.0
TH2_k127_5804831_37 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000001313 108.0
TH2_k127_5804831_38 PHP domain protein - - - 0.000000000000000000001998 97.0
TH2_k127_5804831_39 Protein conserved in bacteria - - - 0.000000000000000000002309 96.0
TH2_k127_5804831_4 Conjugal transfer protein TraG - - - 1.229e-259 811.0
TH2_k127_5804831_40 Transcriptional activator TraM - - - 0.0000000000000000000471 95.0
TH2_k127_5804831_41 Plasmid stabilization system K19092 - - 0.0000000000000000001353 91.0
TH2_k127_5804831_42 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000000255 90.0
TH2_k127_5804831_43 - - - - 0.0000000000000000004419 91.0
TH2_k127_5804831_44 SpoVT / AbrB like domain - - - 0.00000000000000001037 85.0
TH2_k127_5804831_45 Resolvase, N terminal domain - - - 0.00000000000000138 76.0
TH2_k127_5804831_46 Resolvase, N terminal domain - - - 0.00000000000004093 72.0
TH2_k127_5804831_47 - - - - 0.000000000001798 71.0
TH2_k127_5804831_48 Family of unknown function (DUF5338) - - - 0.000000000004475 73.0
TH2_k127_5804831_49 - - - - 0.000000000005829 68.0
TH2_k127_5804831_5 Transposase - - - 2.697e-250 806.0
TH2_k127_5804831_50 Transposase IS116/IS110/IS902 family - - - 0.000000005574 58.0
TH2_k127_5804831_51 Resolvase, N terminal domain - - - 0.0000003093 52.0
TH2_k127_5804831_52 transposition K07497 - - 0.000001334 57.0
TH2_k127_5804831_53 Belongs to the UPF0758 family K03630 - - 0.000008746 57.0
TH2_k127_5804831_54 - - - - 0.0005817 44.0
TH2_k127_5804831_6 PFAM DNA methylase N-4 N-6 domain protein K07316 - 2.1.1.72 2.947e-238 752.0
TH2_k127_5804831_7 flagellar hook-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009343 561.0
TH2_k127_5804831_8 conjugation TrbI family protein K20533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 511.0
TH2_k127_5804831_9 COG4962 Flp pilus assembly protein, ATPase CpaF K20527 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 492.0
TH2_k127_5820594_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 2.562e-223 706.0
TH2_k127_5820594_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 295.0
TH2_k127_5820594_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000006169 204.0
TH2_k127_5846422_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 419.0
TH2_k127_5846422_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000003764 127.0
TH2_k127_5899124_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 4.425e-292 897.0
TH2_k127_5899124_1 PFAM Integrase, catalytic core, phage - - - 1.223e-205 640.0
TH2_k127_5899124_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 287.0
TH2_k127_5899124_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000335 277.0
TH2_k127_5899124_4 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000002777 70.0
TH2_k127_590654_0 dehydrogenase, E1 component K00164 - 1.2.4.2 6.445e-287 886.0
TH2_k127_590654_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.735e-285 877.0
TH2_k127_590654_2 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 482.0
TH2_k127_590654_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 425.0
TH2_k127_590654_4 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000000000000000000000000000008699 154.0
TH2_k127_590654_5 endonuclease activity - - - 0.00000000000000000000000000006801 116.0
TH2_k127_5925168_0 PFAM Glycosyl transferase, family 2 K00721,K00786 - 2.4.1.83 0.0 1632.0
TH2_k127_5925168_1 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 8.8e-322 987.0
TH2_k127_5925168_10 malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 556.0
TH2_k127_5925168_11 PFAM Zinc iron permease K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 484.0
TH2_k127_5925168_12 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 475.0
TH2_k127_5925168_13 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 463.0
TH2_k127_5925168_14 glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 464.0
TH2_k127_5925168_15 Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 454.0
TH2_k127_5925168_16 Protoglobin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 411.0
TH2_k127_5925168_17 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 355.0
TH2_k127_5925168_18 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 322.0
TH2_k127_5925168_19 Protein of unknown function (DUF4019) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006015 250.0
TH2_k127_5925168_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 2.609e-263 816.0
TH2_k127_5925168_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008441 235.0
TH2_k127_5925168_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000009099 211.0
TH2_k127_5925168_22 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000002234 189.0
TH2_k127_5925168_23 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000000003621 146.0
TH2_k127_5925168_24 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000000000001548 129.0
TH2_k127_5925168_25 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0000000000000000000000000001444 115.0
TH2_k127_5925168_26 - - - - 0.0000000000001768 80.0
TH2_k127_5925168_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.217e-260 804.0
TH2_k127_5925168_4 outer membrane efflux protein K15725 - - 1.383e-236 740.0
TH2_k127_5925168_5 Ankyrin repeat K06867 - - 8.067e-224 696.0
TH2_k127_5925168_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 1.43e-214 668.0
TH2_k127_5925168_7 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 3.358e-213 672.0
TH2_k127_5925168_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 2.484e-204 636.0
TH2_k127_5925168_9 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 1.671e-195 612.0
TH2_k127_5929434_0 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0 2903.0
TH2_k127_5929434_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 6.09e-315 968.0
TH2_k127_5929434_10 addiction module antidote protein HigA K21498 - - 0.00000000000000000003542 91.0
TH2_k127_5929434_2 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 5.022e-218 682.0
TH2_k127_5929434_3 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 598.0
TH2_k127_5929434_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 515.0
TH2_k127_5929434_5 RNase_H superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 346.0
TH2_k127_5929434_6 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 324.0
TH2_k127_5929434_7 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000008478 234.0
TH2_k127_5929434_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000000000001042 201.0
TH2_k127_5929434_9 - - - - 0.000000000000000000000000000000000000000000000006263 173.0
TH2_k127_5934171_0 Ketoacyl-synthetase C-terminal extension - - - 0.0 5125.0
TH2_k127_5934171_1 Ketoacyl-synthetase C-terminal extension K15676 - - 0.0 3031.0
TH2_k127_5934171_10 PFAM Peptidase M48 - - - 4.22e-291 897.0
TH2_k127_5934171_11 alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 1.598e-283 872.0
TH2_k127_5934171_12 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 2.252e-259 803.0
TH2_k127_5934171_13 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 8.546e-257 793.0
TH2_k127_5934171_14 OsmC-like protein K06889,K07397 - - 3.927e-244 756.0
TH2_k127_5934171_15 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.13e-243 754.0
TH2_k127_5934171_16 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 1.42e-243 756.0
TH2_k127_5934171_17 MacB-like periplasmic core domain K02004 - - 4.958e-239 741.0
TH2_k127_5934171_18 Alpha/beta hydrolase family - - - 4.676e-232 719.0
TH2_k127_5934171_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 2.854e-207 648.0
TH2_k127_5934171_2 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1804.0
TH2_k127_5934171_20 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 7.763e-207 645.0
TH2_k127_5934171_21 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 1.204e-201 627.0
TH2_k127_5934171_22 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 552.0
TH2_k127_5934171_23 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 531.0
TH2_k127_5934171_24 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 515.0
TH2_k127_5934171_25 PFAM TENA THI-4 protein Coenzyme PQQ biosynthesis protein C K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 492.0
TH2_k127_5934171_26 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009198 472.0
TH2_k127_5934171_27 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 456.0
TH2_k127_5934171_28 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 431.0
TH2_k127_5934171_29 PFAM Signal transduction response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009818 421.0
TH2_k127_5934171_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0 1494.0
TH2_k127_5934171_30 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 415.0
TH2_k127_5934171_31 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 404.0
TH2_k127_5934171_32 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 392.0
TH2_k127_5934171_33 PFAM Exopolysaccharide synthesis, ExoD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 386.0
TH2_k127_5934171_34 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 385.0
TH2_k127_5934171_35 protein conserved in bacteria K09941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 327.0
TH2_k127_5934171_36 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 299.0
TH2_k127_5934171_37 PFAM RNA-binding S4 K04762 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003607 239.0
TH2_k127_5934171_38 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000007419 237.0
TH2_k127_5934171_39 RF-1 domain K15034 - - 0.00000000000000000000000000000000000000000000000000000000000000000004426 233.0
TH2_k127_5934171_4 Histidine kinase - - - 0.0 1368.0
TH2_k127_5934171_40 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000000000000000005788 194.0
TH2_k127_5934171_41 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000000000000000000000005107 187.0
TH2_k127_5934171_42 Zinc-finger domain - - - 0.000000000000000000000000000000000000001052 148.0
TH2_k127_5934171_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0 1108.0
TH2_k127_5934171_6 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0 1037.0
TH2_k127_5934171_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.984e-320 984.0
TH2_k127_5934171_8 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 1.283e-307 944.0
TH2_k127_5934171_9 Ribonuclease E/G family K08301 - - 1.934e-297 914.0
TH2_k127_595781_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - - 0.0 1173.0
TH2_k127_595781_1 von Willebrand factor, type A - - - 2.706e-219 680.0
TH2_k127_595781_2 SMART Signal transduction response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 382.0
TH2_k127_595781_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 379.0
TH2_k127_595781_4 Nucleotidyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001084 243.0
TH2_k127_595781_5 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000000000000000000000000000003304 209.0
TH2_k127_595781_6 Putative motility protein - - - 0.000000000000000000000000000003225 122.0
TH2_k127_595781_7 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.0000000000000000007393 86.0
TH2_k127_6004590_0 PFAM Di-haem cytochrome c peroxidase - - - 0.0 1326.0
TH2_k127_6004590_1 Alginate export - - - 0.0 1028.0
TH2_k127_6004590_10 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 429.0
TH2_k127_6004590_11 Ankyrin repeat K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 341.0
TH2_k127_6004590_12 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 306.0
TH2_k127_6004590_13 Restriction endonuclease K07448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 314.0
TH2_k127_6004590_14 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 297.0
TH2_k127_6004590_2 PFAM amidohydrolase - - - 9.467e-230 720.0
TH2_k127_6004590_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 3.041e-227 706.0
TH2_k127_6004590_4 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 546.0
TH2_k127_6004590_5 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 531.0
TH2_k127_6004590_6 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 520.0
TH2_k127_6004590_7 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 500.0
TH2_k127_6004590_8 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 484.0
TH2_k127_6004590_9 PEP-CTERM motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 470.0
TH2_k127_6004980_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1738.0
TH2_k127_6004980_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.0 1552.0
TH2_k127_6004980_10 Uncharacterized conserved protein (DUF2278) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 597.0
TH2_k127_6004980_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 521.0
TH2_k127_6004980_12 PFAM formate nitrite transporter K02598,K21993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 505.0
TH2_k127_6004980_13 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 484.0
TH2_k127_6004980_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 435.0
TH2_k127_6004980_15 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 434.0
TH2_k127_6004980_16 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 333.0
TH2_k127_6004980_17 Redoxin domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 289.0
TH2_k127_6004980_18 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003256 248.0
TH2_k127_6004980_19 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001351 242.0
TH2_k127_6004980_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0 1444.0
TH2_k127_6004980_20 - - - - 0.0000000000000000000000000000000000000000000000000000000003344 204.0
TH2_k127_6004980_21 - - - - 0.00000000000000000000000000000000000000000000000000005293 190.0
TH2_k127_6004980_22 ABC-2 family transporter protein - - - 0.0000007159 52.0
TH2_k127_6004980_3 Alpha amylase, catalytic domain K01176 - 3.2.1.1 0.0 1313.0
TH2_k127_6004980_4 Involved in the biosynthesis of porphyrin-containing compound - - - 3.692e-254 785.0
TH2_k127_6004980_5 amine dehydrogenase activity - - - 6.327e-250 792.0
TH2_k127_6004980_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 2.109e-219 683.0
TH2_k127_6004980_7 cysteine protease - - - 1.773e-196 615.0
TH2_k127_6004980_8 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 9.313e-194 605.0
TH2_k127_6004980_9 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 605.0
TH2_k127_6018561_0 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.0 1889.0
TH2_k127_6018561_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - - 1.383e-267 831.0
TH2_k127_6018561_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 3.252e-199 623.0
TH2_k127_6018561_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 388.0
TH2_k127_6050655_0 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0 1257.0
TH2_k127_6050655_1 Belongs to the GSP D family K02453 - - 0.0 1170.0
TH2_k127_6050655_10 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 513.0
TH2_k127_6050655_11 Putative neutral zinc metallopeptidase K06973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 442.0
TH2_k127_6050655_12 Type II secretory pathway, pseudopilin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 380.0
TH2_k127_6050655_13 carbon utilization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 350.0
TH2_k127_6050655_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 327.0
TH2_k127_6050655_15 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 316.0
TH2_k127_6050655_16 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 308.0
TH2_k127_6050655_17 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 312.0
TH2_k127_6050655_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 302.0
TH2_k127_6050655_19 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 285.0
TH2_k127_6050655_2 type II secretion system protein E K02454 - - 0.0 1083.0
TH2_k127_6050655_20 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 284.0
TH2_k127_6050655_21 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000117 260.0
TH2_k127_6050655_22 PFAM type II secretion system protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000328 239.0
TH2_k127_6050655_23 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000000000001581 142.0
TH2_k127_6050655_24 DDE superfamily endonuclease - - - 0.000000000000000000000000005997 111.0
TH2_k127_6050655_25 Histidine kinase - - - 0.0000000000000000001223 90.0
TH2_k127_6050655_3 SMART ATPase, AAA type, core K06148 - - 0.0 1033.0
TH2_k127_6050655_4 DNA polymerase III K01141 - 3.1.11.1 3.568e-285 878.0
TH2_k127_6050655_5 modulator of DNA gyrase K03592 - - 1.767e-283 873.0
TH2_k127_6050655_6 PFAM Peptidase S8 S53, subtilisin kexin sedolisin - - - 2.407e-282 870.0
TH2_k127_6050655_7 Type II secretion system K02455 - - 3.104e-245 758.0
TH2_k127_6050655_8 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 1.739e-244 757.0
TH2_k127_6050655_9 - - - - 3.109e-196 616.0
TH2_k127_6078260_0 DDE superfamily endonuclease - - - 9.077e-228 706.0
TH2_k127_6078260_1 - - - - 0.0000000000000000000000000000000000000000007055 160.0
TH2_k127_6078260_2 - - - - 0.0000000000000000000000004165 109.0
TH2_k127_6082251_0 DNA topoisomerase, type IA, central K03169 - 5.99.1.2 0.0 1640.0
TH2_k127_6082251_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1116.0
TH2_k127_6082251_10 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000001242 76.0
TH2_k127_6082251_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 3.655e-266 824.0
TH2_k127_6082251_3 DNA recombination-mediator protein A K04096 - - 3.851e-218 679.0
TH2_k127_6082251_4 Lysin motif - - - 8.419e-211 662.0
TH2_k127_6082251_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 407.0
TH2_k127_6082251_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 352.0
TH2_k127_6082251_7 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 313.0
TH2_k127_6082251_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000000000000002868 184.0
TH2_k127_6082251_9 - - - - 0.000000000000000000000000000000000000000001435 156.0
TH2_k127_6089779_0 beta-galactosidase activity - - - 9.633e-210 672.0
TH2_k127_6089779_1 MFS/sugar transport protein K03292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 394.0
TH2_k127_6089779_2 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 337.0
TH2_k127_6089779_3 Transposase K03589,K07491 - - 0.000000000000000000000000000000000000000000000000008242 186.0
TH2_k127_6089779_4 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.00000000000000000000000000000000000000000000002171 192.0
TH2_k127_6089779_5 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000005491 165.0
TH2_k127_6108215_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0 1026.0
TH2_k127_6108215_1 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 391.0
TH2_k127_6108215_2 Anti sigma-E protein RseA, N-terminal domain K03597 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 335.0
TH2_k127_6108215_3 MucB/RseB C-terminal domain K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003247 271.0
TH2_k127_6169487_0 Metallo-peptidase family M12B Reprolysin-like - - - 3.037e-293 905.0
TH2_k127_6169487_1 Protein tyrosine kinase K08282 - 2.7.11.1 2.94e-237 743.0
TH2_k127_6169487_2 sequence-specific DNA binding - - - 0.0001134 46.0
TH2_k127_6175515_0 Outer membrane efflux protein - - - 1.074e-237 743.0
TH2_k127_6175515_1 FtsX-like permease family K02004 - - 6.778e-208 650.0
TH2_k127_6175515_10 PFAM Transposase, IS4-like K07481 - - 0.0000000000000000000000005354 106.0
TH2_k127_6175515_11 ubiquitin - - - 0.0000000000000006394 84.0
TH2_k127_6175515_12 addiction module killer protein - - - 0.00000002786 55.0
TH2_k127_6175515_13 addiction module killer protein - - - 0.00002656 46.0
TH2_k127_6175515_2 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 568.0
TH2_k127_6175515_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 414.0
TH2_k127_6175515_4 pilus organization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 316.0
TH2_k127_6175515_5 MafB19-like deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000001298 232.0
TH2_k127_6175515_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000001609 183.0
TH2_k127_6175515_7 Fungal family of unknown function (DUF1776) - - - 0.0000000000000000000000000000000000000000003734 157.0
TH2_k127_6175515_8 type I site-specific restriction-modification system, R subunit K01153 - 3.1.21.3 0.0000000000000000000000000000000000183 136.0
TH2_k127_6175515_9 GYD domain - - - 0.00000000000000000000000000000004376 127.0
TH2_k127_6177571_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.849e-253 782.0
TH2_k127_6177571_1 Nucleoside H+ symporter K05820 - - 6.36e-246 760.0
TH2_k127_6177571_2 Rubrerythrin - - - 0.000006587 48.0
TH2_k127_6183762_0 BT1 family - - - 0.0 1033.0
TH2_k127_6183762_1 MltA specific insert domain K08304 - - 3.725e-256 790.0
TH2_k127_6183762_11 PFAM Integrase, catalytic core K07497 - - 0.00003723 46.0
TH2_k127_6183762_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 2.851e-243 754.0
TH2_k127_6183762_3 Belongs to the peptidase S1C family K04691,K04772 - - 8.154e-226 702.0
TH2_k127_6183762_4 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 473.0
TH2_k127_6183762_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 473.0
TH2_k127_6183762_6 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 375.0
TH2_k127_6183762_7 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000321 150.0
TH2_k127_6183762_8 Competence protein ComEA K02237 - - 0.0000000000000000000000000000000000001568 143.0
TH2_k127_6183762_9 PEP-CTERM motif - - - 0.0000000000000000005606 88.0
TH2_k127_6189019_0 PFAM Major facilitator superfamily K08218 - - 1.563e-278 859.0
TH2_k127_6189019_1 Cell wall hydrolase autolysin K01448 - 3.5.1.28 5.12e-268 830.0
TH2_k127_6189019_10 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 443.0
TH2_k127_6189019_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 376.0
TH2_k127_6189019_12 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 352.0
TH2_k127_6189019_13 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 335.0
TH2_k127_6189019_14 Response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000045 252.0
TH2_k127_6189019_15 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000001753 164.0
TH2_k127_6189019_16 small periplasmic lipoprotein - - - 0.000000000004374 66.0
TH2_k127_6189019_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.188e-257 796.0
TH2_k127_6189019_3 PFAM Squalene phytoene synthase K00801 - 2.5.1.21 2.446e-218 679.0
TH2_k127_6189019_4 Permease MlaE K02066 - - 7.011e-217 676.0
TH2_k127_6189019_5 NmrA-like family K00091 - 1.1.1.219 4.411e-205 639.0
TH2_k127_6189019_6 AFG1-like ATPase K06916 - - 1.11e-201 629.0
TH2_k127_6189019_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 557.0
TH2_k127_6189019_8 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 547.0
TH2_k127_6189019_9 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 520.0
TH2_k127_6250876_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1349.0
TH2_k127_6250876_1 Signal transduction histidine kinase - - - 0.0 1329.0
TH2_k127_6250876_10 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 1.543e-215 670.0
TH2_k127_6250876_11 Inositol monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009173 535.0
TH2_k127_6250876_12 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 473.0
TH2_k127_6250876_13 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 452.0
TH2_k127_6250876_14 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 388.0
TH2_k127_6250876_15 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 357.0
TH2_k127_6250876_16 Domain of unknown function (DUF4357) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 297.0
TH2_k127_6250876_17 Response regulator receiver K02657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004685 242.0
TH2_k127_6250876_18 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000000000000003599 190.0
TH2_k127_6250876_19 Domain of unknown function (DUF4357) - - - 0.00000000000000017 80.0
TH2_k127_6250876_2 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 4.995e-303 930.0
TH2_k127_6250876_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.088e-301 926.0
TH2_k127_6250876_4 TrkA-N domain protein K03499 - - 4.922e-285 878.0
TH2_k127_6250876_5 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 2.175e-278 857.0
TH2_k127_6250876_6 Sigma-54 interaction domain - - - 6.48e-261 805.0
TH2_k127_6250876_7 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 2.113e-254 787.0
TH2_k127_6250876_8 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 1.293e-246 763.0
TH2_k127_6250876_9 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 2.069e-229 710.0
TH2_k127_6348875_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1173.0
TH2_k127_6348875_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.489e-268 828.0
TH2_k127_6348875_10 Putative regulatory protein - - - 0.000000000000000000000000000000000000000002575 157.0
TH2_k127_6348875_11 FR47-like protein - - - 0.0000000000000699 71.0
TH2_k127_6348875_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 557.0
TH2_k127_6348875_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 530.0
TH2_k127_6348875_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 335.0
TH2_k127_6348875_5 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 292.0
TH2_k127_6348875_6 Nudix hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006407 274.0
TH2_k127_6348875_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001836 255.0
TH2_k127_6348875_8 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000001607 214.0
TH2_k127_6348875_9 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.0000000000000000000000000000000000000000000000367 169.0
TH2_k127_6450988_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1320.0
TH2_k127_6450988_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0 1059.0
TH2_k127_6450988_2 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006878 259.0
TH2_k127_6450988_3 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000000000003522 134.0
TH2_k127_6460833_0 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 572.0
TH2_k127_6460833_1 Protein of unknown function (DUF3465) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 289.0
TH2_k127_6460833_2 - - - - 0.00000000000000000000000000000000000000000000000000006821 187.0
TH2_k127_6460833_3 Serine aminopeptidase, S33 K06889 - - 0.0001951 44.0
TH2_k127_6462487_0 M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1343.0
TH2_k127_6462487_1 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 1.181e-273 842.0
TH2_k127_6462487_10 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 513.0
TH2_k127_6462487_11 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 509.0
TH2_k127_6462487_12 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 501.0
TH2_k127_6462487_13 Cytidylyltransferase K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 484.0
TH2_k127_6462487_14 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 481.0
TH2_k127_6462487_15 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 437.0
TH2_k127_6462487_16 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 408.0
TH2_k127_6462487_17 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 398.0
TH2_k127_6462487_18 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 392.0
TH2_k127_6462487_19 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 359.0
TH2_k127_6462487_2 Dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 6.908e-272 838.0
TH2_k127_6462487_20 invasion associated locus B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 336.0
TH2_k127_6462487_21 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 327.0
TH2_k127_6462487_22 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 320.0
TH2_k127_6462487_23 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002967 245.0
TH2_k127_6462487_24 Belongs to the ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000002956 216.0
TH2_k127_6462487_25 Domain of unknown function (DUF2024) - - - 0.000000000000000000000000000000000000000000000002501 173.0
TH2_k127_6462487_26 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000000000005349 173.0
TH2_k127_6462487_27 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000000000000001447 170.0
TH2_k127_6462487_29 Rubredoxin - - - 0.0000000000000008113 77.0
TH2_k127_6462487_3 Cysteine-rich domain K11473 - - 8.193e-264 815.0
TH2_k127_6462487_30 hmm pf01609 - - - 0.000000001584 62.0
TH2_k127_6462487_4 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 3.321e-200 624.0
TH2_k127_6462487_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 7.32e-199 620.0
TH2_k127_6462487_6 PFAM Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 607.0
TH2_k127_6462487_7 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 569.0
TH2_k127_6462487_8 O-Antigen ligase K02847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 541.0
TH2_k127_6462487_9 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 516.0
TH2_k127_6474767_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1600.0
TH2_k127_6474767_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 4.588e-290 892.0
TH2_k127_6474767_10 DEAD-like helicase, N-terminal - - - 0.00000000000000000000000000000000000000000000000007341 177.0
TH2_k127_6474767_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 4.571e-284 874.0
TH2_k127_6474767_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 3.548e-207 647.0
TH2_k127_6474767_4 TIGRFAM type I secretion outer membrane protein, TolC K12340 - - 3.555e-206 649.0
TH2_k127_6474767_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 544.0
TH2_k127_6474767_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 495.0
TH2_k127_6474767_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 479.0
TH2_k127_6474767_8 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 411.0
TH2_k127_6474767_9 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 329.0
TH2_k127_6516355_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1420.0
TH2_k127_6516355_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1253.0
TH2_k127_6516355_10 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 341.0
TH2_k127_6516355_11 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000002481 233.0
TH2_k127_6516355_12 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000000000000000003148 226.0
TH2_k127_6516355_13 Small metal-binding protein - - - 0.000000000000000000000000000000000000000000000000005247 184.0
TH2_k127_6516355_14 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000002482 168.0
TH2_k127_6516355_15 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000000000005404 122.0
TH2_k127_6516355_2 Threonine synthase K01733 - 4.2.3.1 1.888e-272 840.0
TH2_k127_6516355_3 PFAM aminotransferase, class I K14260 - 2.6.1.2,2.6.1.66 9.197e-270 831.0
TH2_k127_6516355_4 homoserine dehydrogenase K00003 - 1.1.1.3 3.637e-259 801.0
TH2_k127_6516355_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 6.441e-220 682.0
TH2_k127_6516355_6 Lysin motif K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 605.0
TH2_k127_6516355_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 506.0
TH2_k127_6516355_8 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 474.0
TH2_k127_6516355_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 404.0
TH2_k127_6714960_0 Signal transduction response regulator, receiver - - - 8.506e-231 716.0
TH2_k127_6714960_1 PFAM Transposase, IS4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 354.0
TH2_k127_6714960_2 Transposase K07492 - - 0.000000000000000000000000000000000000000000000001471 177.0
TH2_k127_6714960_3 Transposase K07492 - - 0.0000000000000000000000000000000000000001505 154.0
TH2_k127_6714960_4 transposase activity - - - 0.00000000000000000000000008007 108.0
TH2_k127_6714960_5 transposition - - - 0.0000000000000006696 78.0
TH2_k127_6714960_6 PFAM Transposase, IS4-like K07481 - - 0.0000000000001125 70.0
TH2_k127_6714960_7 - - - - 0.00000000004587 73.0
TH2_k127_6717002_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 5.251e-292 899.0
TH2_k127_6717002_1 decarboxylase - - - 1.606e-284 875.0
TH2_k127_6717002_10 Belongs to the UPF0225 family K09858 - - 0.00000000000000000000000000000000000000000000000000000000000000000001279 234.0
TH2_k127_6717002_11 Small Multidrug Resistance protein K03297 - - 0.0000000000000000000000000000000000000000000000000000001376 196.0
TH2_k127_6717002_12 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.000000000000000000000000000000000000000000000000000003039 190.0
TH2_k127_6717002_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000000000000000000001338 189.0
TH2_k127_6717002_14 PFAM Glutamine amidotransferase class-I K01658 - 4.1.3.27 0.00000000000000000000823 92.0
TH2_k127_6717002_2 - - - - 2.749e-238 739.0
TH2_k127_6717002_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 3.971e-214 668.0
TH2_k127_6717002_4 D-isomer specific 2-hydroxyacid dehydrogenase K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 1.053e-202 632.0
TH2_k127_6717002_5 PFAM Type IV pilus assembly PilZ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 493.0
TH2_k127_6717002_6 PFAM Abortive infection protein K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 439.0
TH2_k127_6717002_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 359.0
TH2_k127_6717002_8 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 291.0
TH2_k127_6717002_9 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003874 271.0
TH2_k127_6734540_0 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004364 272.0
TH2_k127_6734540_1 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000000000000002106 146.0
TH2_k127_6752320_0 - - - - 0.0 1162.0
TH2_k127_6752320_1 ABC transporter transmembrane region K06147 - - 0.0 1108.0
TH2_k127_6752320_10 deaminase zinc-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 364.0
TH2_k127_6752320_11 PFAM Outer membrane protein, OmpA MotB, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 329.0
TH2_k127_6752320_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 324.0
TH2_k127_6752320_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005509 259.0
TH2_k127_6752320_14 - - - - 0.00000000000000000000000000000000000000000000000000000000001596 206.0
TH2_k127_6752320_15 Protein of unknown function (DUF2798) - - - 0.000000000000000000000000000000000000003278 146.0
TH2_k127_6752320_16 - - - - 0.00000000000000000000000000325 115.0
TH2_k127_6752320_17 PFAM Transposase, IS4-like - - - 0.0000000000007559 69.0
TH2_k127_6752320_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0 1055.0
TH2_k127_6752320_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 4.805e-290 892.0
TH2_k127_6752320_4 Psort location CytoplasmicMembrane, score 10.00 - - - 3.987e-238 740.0
TH2_k127_6752320_5 AAA domain K02450 - - 1.428e-229 715.0
TH2_k127_6752320_6 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 558.0
TH2_k127_6752320_7 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 553.0
TH2_k127_6752320_8 tRNA (guanine-N7-)-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 441.0
TH2_k127_6752320_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 374.0
TH2_k127_6801957_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1482.0
TH2_k127_6801957_1 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0 1333.0
TH2_k127_6801957_10 - - - - 0.000000000000000000003671 94.0
TH2_k127_6801957_2 Cytochrome c - - - 0.0 1193.0
TH2_k127_6801957_3 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1097.0
TH2_k127_6801957_4 Belongs to the GPI family K01810 - 5.3.1.9 0.0 1065.0
TH2_k127_6801957_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.186e-308 947.0
TH2_k127_6801957_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 9.118e-272 838.0
TH2_k127_6801957_7 PFAM Transposase, IS4-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000004362 235.0
TH2_k127_6801957_8 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000006654 151.0
TH2_k127_6801957_9 PFAM Chemotaxis methyl-accepting receptor, signalling K03406,K03776,K05874 - - 0.00000000000000000000002137 105.0
TH2_k127_6839325_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1880.0
TH2_k127_6839325_1 PFAM Peptidase M17, leucyl aminopeptidase K01255 - 3.4.11.1 1.476e-302 929.0
TH2_k127_6839325_10 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 390.0
TH2_k127_6839325_11 phosphatase activity K01560,K07025,K20866,K21063 GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104,3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 382.0
TH2_k127_6839325_12 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 319.0
TH2_k127_6839325_13 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 282.0
TH2_k127_6839325_14 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 282.0
TH2_k127_6839325_15 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000000000000000000001058 177.0
TH2_k127_6839325_16 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000000000000000000000002162 174.0
TH2_k127_6839325_17 ParD-like antitoxin of type II bacterial toxin-antitoxin system - - - 0.000000000000000000001409 94.0
TH2_k127_6839325_18 ParE-like toxin of type II bacterial toxin-antitoxin system - - - 0.00000000000001935 74.0
TH2_k127_6839325_2 Lysin motif K08307 - - 1.518e-258 799.0
TH2_k127_6839325_3 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 4.39e-256 790.0
TH2_k127_6839325_4 TIGRFAM TIGR03790 family protein - - - 3.289e-241 753.0
TH2_k127_6839325_5 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 2.043e-237 736.0
TH2_k127_6839325_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 526.0
TH2_k127_6839325_7 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 480.0
TH2_k127_6839325_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 415.0
TH2_k127_6839325_9 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 400.0
TH2_k127_6860937_0 PFAM TonB-dependent receptor, beta-barrel - - - 0.0 1829.0
TH2_k127_6860937_1 EAL domain - - - 0.0 1157.0
TH2_k127_6860937_10 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 552.0
TH2_k127_6860937_11 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 541.0
TH2_k127_6860937_12 Sodium Bile acid symporter family K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 490.0
TH2_k127_6860937_13 TIGRFAM Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 455.0
TH2_k127_6860937_14 Protein of unknown function (DUF3450) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 419.0
TH2_k127_6860937_15 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 369.0
TH2_k127_6860937_16 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 337.0
TH2_k127_6860937_17 Esterase-like activity of phytase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006161 259.0
TH2_k127_6860937_18 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002689 252.0
TH2_k127_6860937_19 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005395 254.0
TH2_k127_6860937_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0 1059.0
TH2_k127_6860937_20 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000000000000000001731 231.0
TH2_k127_6860937_21 - - - - 0.000000000000000000000000000000000000000000000000000000001057 203.0
TH2_k127_6860937_22 Esterase-like activity of phytase - - - 0.000000000000000000000000000000000000000000000000000005375 191.0
TH2_k127_6860937_23 - - - - 0.0000000000000000000000000000000001892 133.0
TH2_k127_6860937_3 domain, Protein - - - 2.254e-309 952.0
TH2_k127_6860937_4 Glycosyl transferase family 1 - - - 2.494e-229 710.0
TH2_k127_6860937_5 PFAM MotA TolQ ExbB proton channel K03561 - - 1.427e-218 688.0
TH2_k127_6860937_6 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 8.305e-216 671.0
TH2_k127_6860937_7 TPR repeat - - - 3.379e-215 672.0
TH2_k127_6860937_8 PFAM Diacylglycerol kinase, catalytic - - - 1.788e-204 638.0
TH2_k127_6860937_9 probably responsible for the translocation of the substrate across the membrane K02037 - - 2.548e-194 607.0
TH2_k127_6865375_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.0 1306.0
TH2_k127_6865375_1 lipid A ABC exporter family, fused ATPase and inner membrane subunits K06147 - - 0.0 1034.0
TH2_k127_6865375_10 TIGRFAM methyltransferase FkbM family - - - 0.00000000000000002226 86.0
TH2_k127_6865375_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 1.059e-263 817.0
TH2_k127_6865375_3 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 474.0
TH2_k127_6865375_4 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 385.0
TH2_k127_6865375_5 Phosphorylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000346 250.0
TH2_k127_6865375_6 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004188 241.0
TH2_k127_6865375_7 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000003039 182.0
TH2_k127_6865375_8 - - - - 0.0000000000000000000000000000000000000009521 150.0
TH2_k127_6865375_9 transposition - - - 0.0000000000000000000000002157 109.0
TH2_k127_6873638_1 Formate acetyltransferase K00656 - 2.3.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 503.0
TH2_k127_6990531_0 RNA polymerase recycling family C-terminal K03580 - - 0.0 1700.0
TH2_k127_6990531_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1633.0
TH2_k127_6990531_10 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 505.0
TH2_k127_6990531_11 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 481.0
TH2_k127_6990531_12 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 479.0
TH2_k127_6990531_13 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 450.0
TH2_k127_6990531_14 Protein of unknown function (DUF2490) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 362.0
TH2_k127_6990531_15 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 342.0
TH2_k127_6990531_16 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 336.0
TH2_k127_6990531_17 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 319.0
TH2_k127_6990531_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 306.0
TH2_k127_6990531_19 Belongs to the skp family K06142 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 289.0
TH2_k127_6990531_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1421.0
TH2_k127_6990531_20 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 287.0
TH2_k127_6990531_21 Cytochrome C oxidase, cbb3-type, subunit III K12263 - - 0.000000000000000000000000000000000000000000000000000001963 191.0
TH2_k127_6990531_22 Restriction endonuclease - - - 0.00000000000000000000000000000000006184 134.0
TH2_k127_6990531_23 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000001097 120.0
TH2_k127_6990531_24 cytochrome - - - 0.000008338 49.0
TH2_k127_6990531_3 zinc metalloprotease K11749 - - 1.321e-282 870.0
TH2_k127_6990531_4 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 4.975e-275 850.0
TH2_k127_6990531_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 1.041e-243 757.0
TH2_k127_6990531_6 PFAM Glutaredoxin - - - 6.237e-227 708.0
TH2_k127_6990531_7 T5orf172 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 600.0
TH2_k127_6990531_8 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 539.0
TH2_k127_6990531_9 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 508.0
TH2_k127_7046596_0 Formate acetyltransferase K00656 - 2.3.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 501.0
TH2_k127_7046596_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001114 276.0
TH2_k127_7046596_2 - - - - 0.00000000000000000000000000000000000000000000000000000003858 198.0
TH2_k127_7086570_0 MMPL family K07003 - - 0.0 1544.0
TH2_k127_7086570_1 Selenide, water dikinase K01008 - 2.7.9.3 0.0 1330.0
TH2_k127_7086570_10 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 1.023e-218 679.0
TH2_k127_7086570_11 AI-2E family transporter - - - 9.467e-214 665.0
TH2_k127_7086570_12 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 3.129e-208 650.0
TH2_k127_7086570_13 flagellar motor switch protein FliM K02416 - - 9.35e-199 620.0
TH2_k127_7086570_14 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 563.0
TH2_k127_7086570_15 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 482.0
TH2_k127_7086570_16 Role in flagellar biosynthesis K02421 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 468.0
TH2_k127_7086570_17 TIGRFAM HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 455.0
TH2_k127_7086570_18 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 438.0
TH2_k127_7086570_19 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 404.0
TH2_k127_7086570_2 AMP-dependent synthetase K00666 - - 0.0 1183.0
TH2_k127_7086570_20 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 396.0
TH2_k127_7086570_21 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 375.0
TH2_k127_7086570_22 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 355.0
TH2_k127_7086570_23 Flagellar motor switch K02417,K03225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 291.0
TH2_k127_7086570_24 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003969 272.0
TH2_k127_7086570_25 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007264 223.0
TH2_k127_7086570_26 PFAM Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000001608 217.0
TH2_k127_7086570_27 Role in flagellar biosynthesis K02420 - - 0.0000000000000000000000000000000000000000000007985 166.0
TH2_k127_7086570_28 Phosphopantetheine attachment site - - - 0.00000000000000000000000000000000000000002357 153.0
TH2_k127_7086570_29 flagellar biosynthesis protein K02418 - - 0.00000000000000000000000000000000005417 138.0
TH2_k127_7086570_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.335e-320 983.0
TH2_k127_7086570_31 glycosyl transferase, family 2 - - - 0.00002569 47.0
TH2_k127_7086570_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 1.31e-295 908.0
TH2_k127_7086570_5 Membrane - - - 2.695e-268 837.0
TH2_k127_7086570_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 1.693e-265 819.0
TH2_k127_7086570_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 6.176e-255 788.0
TH2_k127_7086570_8 PFAM aminotransferase, class I K00652 - 2.3.1.47 1.381e-250 774.0
TH2_k127_7086570_9 Domain of unknown function (DUF3463) - - - 8.415e-249 768.0
TH2_k127_7178915_0 ATPases associated with a variety of cellular activities - - - 2.624e-206 651.0
TH2_k127_7191132_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1471.0
TH2_k127_7191132_1 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 335.0
TH2_k127_7191132_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000288 264.0
TH2_k127_7210749_0 D-isomer specific 2-hydroxyacid dehydrogenase K03778 - 1.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 355.0
TH2_k127_7210749_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000000000001381 170.0
TH2_k127_7210749_2 VanZ like family - - - 0.000000000000672 73.0
TH2_k127_7210749_3 D-isomer specific 2-hydroxyacid dehydrogenase K03778 - 1.1.1.28 0.00000000003529 66.0
TH2_k127_7216362_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1091.0
TH2_k127_7216362_1 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 6.019e-244 754.0
TH2_k127_7216362_10 PFAM Cytochrome c, class I K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000005863 190.0
TH2_k127_7216362_11 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000000000000000000000003818 170.0
TH2_k127_7216362_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 1.33e-206 642.0
TH2_k127_7216362_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 566.0
TH2_k127_7216362_4 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 548.0
TH2_k127_7216362_5 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 456.0
TH2_k127_7216362_6 Protein of unknown function (DUF2914) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 416.0
TH2_k127_7216362_7 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 372.0
TH2_k127_7216362_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 346.0
TH2_k127_7216362_9 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001386 276.0
TH2_k127_7273302_0 AMP-dependent synthetase K01897 - 6.2.1.3 0.0 1081.0
TH2_k127_7273302_1 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001208 243.0
TH2_k127_7273302_2 Helix-hairpin-helix domain - - - 0.0000000000000000000000000000000000001936 145.0
TH2_k127_7273302_3 Phosphoglycerate mutase family K08296 - - 0.000000000000000001651 85.0
TH2_k127_7305959_0 Belongs to the sulfur carrier protein TusA family - - - 1.867e-236 734.0
TH2_k127_7305959_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.449e-221 689.0
TH2_k127_7305959_2 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 571.0
TH2_k127_7305959_3 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 554.0
TH2_k127_7305959_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 318.0
TH2_k127_7305959_5 UvrD REP K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 303.0
TH2_k127_7305959_6 Glycine-zipper domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 297.0
TH2_k127_7305959_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005933 263.0
TH2_k127_7305959_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001148 259.0
TH2_k127_7305959_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000003404 216.0
TH2_k127_7366157_0 helicase superfamily c-terminal domain K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 4.448e-266 822.0
TH2_k127_7366157_1 Belongs to the 'phage' integrase family - - - 2.162e-229 715.0
TH2_k127_7366157_2 Pfam:Methyltransf_26 - - - 5.82e-222 691.0
TH2_k127_7366157_3 TIGRFAM Addiction module killer protein, HI1419 - - - 0.0000000000000000000000000000000000000000000000000000000002427 203.0
TH2_k127_7366157_4 MazG-like family - - - 0.000000000000000000000000000000000000000000000000000008216 190.0
TH2_k127_7366157_5 addiction module antidote protein - - - 0.000000000000000000000000000000000000000000000000005581 181.0
TH2_k127_7366157_6 NAD(P)H-binding K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000009609 168.0
TH2_k127_7366157_7 Cupin domain - - - 0.000000000000000000000000003668 112.0
TH2_k127_7504077_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1734.0
TH2_k127_7504077_1 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 0.0 1483.0
TH2_k127_7504077_10 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 455.0
TH2_k127_7504077_11 SMART Diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 473.0
TH2_k127_7504077_12 Glutathione S-transferase, N-terminal domain K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 399.0
TH2_k127_7504077_13 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 395.0
TH2_k127_7504077_14 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 387.0
TH2_k127_7504077_15 Tyrosine phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 325.0
TH2_k127_7504077_16 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 285.0
TH2_k127_7504077_17 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004518 251.0
TH2_k127_7504077_18 stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000000000000000000000000000000006661 236.0
TH2_k127_7504077_19 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000007102 215.0
TH2_k127_7504077_2 ribonuclease II K01147 - 3.1.13.1 0.0 1165.0
TH2_k127_7504077_20 transcriptional regulator, ArsR - - - 0.0000000000000000000000000000000000000000000000000000005954 193.0
TH2_k127_7504077_21 transposition K07497 - - 0.000000000000000000000000000000000000000000000000001072 191.0
TH2_k127_7504077_22 transporter component K07112 - - 0.0000000000000000000000000000000003396 132.0
TH2_k127_7504077_23 transposition K07497 - - 0.000000000000000000000000000003892 124.0
TH2_k127_7504077_25 - - - - 0.000003396 49.0
TH2_k127_7504077_3 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 7.961e-295 910.0
TH2_k127_7504077_4 Acts as a magnesium transporter K06213 - - 1.039e-287 886.0
TH2_k127_7504077_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 6.101e-266 819.0
TH2_k127_7504077_6 Peptidase family M23 K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 578.0
TH2_k127_7504077_7 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 578.0
TH2_k127_7504077_8 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 547.0
TH2_k127_7504077_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 475.0
TH2_k127_7591576_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02621 - - 0.0 1416.0
TH2_k127_7591576_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02622 - - 0.0 1237.0
TH2_k127_7591576_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 3.485e-202 631.0
TH2_k127_7591576_3 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 526.0
TH2_k127_7591576_4 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 501.0
TH2_k127_7591576_5 PFAM Glutamine amidotransferase class-I K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 381.0
TH2_k127_7591576_6 OST-HTH/LOTUS domain - - - 0.0000000000000002671 78.0
TH2_k127_7593584_0 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 9.866e-201 626.0
TH2_k127_7593584_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 - 6.2.1.5,6.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 571.0
TH2_k127_7593584_2 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 572.0
TH2_k127_7593584_3 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 524.0
TH2_k127_7593584_4 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 485.0
TH2_k127_7593584_5 Trm112p-like protein K09791 - - 0.0000000000000000000000000000006062 121.0
TH2_k127_7682448_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 2.004e-297 917.0
TH2_k127_7682448_1 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 6.976e-279 860.0
TH2_k127_7682448_10 amine dehydrogenase activity - - - 0.000000000000000000006408 94.0
TH2_k127_7682448_2 Phosphotransferase enzyme family K07102 - 2.7.1.221 2.259e-207 646.0
TH2_k127_7682448_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 501.0
TH2_k127_7682448_4 Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 434.0
TH2_k127_7682448_5 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 395.0
TH2_k127_7682448_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000007356 218.0
TH2_k127_7682448_7 Membrane fusogenic activity K09806 - - 0.00000000000000000000000000000000000000000000374 166.0
TH2_k127_7682448_8 - K07039 - - 0.0000000000000000000000000000000000008106 139.0
TH2_k127_7682448_9 ThiS family K03154 - - 0.00000000000000000000000000000000001296 136.0
TH2_k127_773398_0 Protein of unknown function, DUF484 K02488 - 2.7.7.65 2.447e-234 726.0
TH2_k127_773398_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 9.801e-218 680.0
TH2_k127_773398_10 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000000000000000000002828 124.0
TH2_k127_773398_11 Domain of unknown function (DUF4372) - - - 0.0000003845 56.0
TH2_k127_773398_2 ABC transporter K06147 - - 7.656e-206 642.0
TH2_k127_773398_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 581.0
TH2_k127_773398_4 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 562.0
TH2_k127_773398_5 PFAM RNA polymerase sigma factor 70, region 4 type 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 361.0
TH2_k127_773398_6 Protein of unknown function (DUF3619) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 287.0
TH2_k127_773398_7 PFAM Sulfotransferase K01014 - 2.8.2.1 0.0000000000000000000000000000000000000002356 149.0
TH2_k127_773398_8 Cold shock protein domain K03704 - - 0.000000000000000000000000000000000000004569 145.0
TH2_k127_773398_9 Protein of unknown function (DUF1353) - - - 0.0000000000000000000000000000000236 128.0
TH2_k127_7789532_0 CoA binding domain K09181 - - 0.0 1710.0
TH2_k127_7789532_1 extracellular solute-binding protein, family 5 - - - 0.0 1422.0
TH2_k127_7789532_2 L-serine dehydratase single chain form K01752 - 4.3.1.17 9.198e-292 897.0
TH2_k127_7789532_3 Protein of unknown function (DUF3422) - - - 1.363e-274 847.0
TH2_k127_7789532_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 3.441e-197 616.0
TH2_k127_7789532_5 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 595.0
TH2_k127_7789532_6 Peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 533.0
TH2_k127_7789532_7 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 514.0
TH2_k127_7789532_8 PFAM thioesterase superfamily K19222 - 3.1.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 323.0
TH2_k127_7789532_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003255 269.0
TH2_k127_7808068_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.0 1009.0
TH2_k127_7808068_1 PFAM ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 1.985e-247 766.0
TH2_k127_7808068_2 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 3.015e-199 621.0
TH2_k127_7808068_3 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 597.0
TH2_k127_7808068_4 CHAP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 467.0
TH2_k127_7808068_5 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 313.0
TH2_k127_7808068_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004297 240.0
TH2_k127_7808068_7 Response regulator receiver K02487,K03407,K06596 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000001853 185.0
TH2_k127_7829770_0 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 563.0
TH2_k127_7829770_1 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 475.0
TH2_k127_7829770_2 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 384.0
TH2_k127_7829770_3 HupE UreJ protein K03192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 330.0
TH2_k127_7829770_4 TPM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 303.0
TH2_k127_7829770_5 hydrogenase maturation protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005967 262.0
TH2_k127_7829770_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007287 247.0
TH2_k127_7829770_7 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000000000000000000000000002225 209.0
TH2_k127_7829770_8 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000000000001277 171.0
TH2_k127_7829770_9 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase, WcaJ K03606 - - 0.000000000000000000007449 91.0
TH2_k127_7841344_0 SMART Diguanylate phosphodiesterase - - - 4.03e-269 831.0
TH2_k127_7841344_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 2.516e-245 763.0
TH2_k127_7850032_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 577.0
TH2_k127_7850032_1 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 436.0
TH2_k127_7850032_2 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 380.0
TH2_k127_7850032_3 transporter antisigma-factor antagonist STAS K07122 - - 0.0000000000000000000000000000000000000000000000000000007215 193.0
TH2_k127_7868905_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1154.0
TH2_k127_7868905_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0 1014.0
TH2_k127_7868905_2 ISXO2-like transposase domain - - - 1.573e-214 666.0
TH2_k127_7868905_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 375.0
TH2_k127_7868905_4 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001061 244.0
TH2_k127_7868905_5 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000000000000000000000000001266 151.0
TH2_k127_7873181_0 Neisseria PilC beta-propeller domain K02674 - - 0.0 1504.0
TH2_k127_7873181_1 TYPE 4 fimbrial BIOGENESIS K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 536.0
TH2_k127_7873181_2 type IV pilus modification protein PilV K02671 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009864 267.0
TH2_k127_7873181_3 Type II transport protein GspH K08084 - - 0.000000000000000000000000000000000000000000000000000000000000000000008506 238.0
TH2_k127_7873181_4 Pilus assembly protein PilX - - - 0.000000000000000000000000000000000000000000000000000000000000001711 221.0
TH2_k127_7873181_5 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000000000000000000000000000000000004759 181.0
TH2_k127_7873181_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000006423 115.0
TH2_k127_7892334_0 PFAM Copper resistance D K07245 - - 0.0 1312.0
TH2_k127_7892334_1 DNA polymerase X family K02347 - - 0.0 1115.0
TH2_k127_7892334_10 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 416.0
TH2_k127_7892334_11 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 367.0
TH2_k127_7892334_12 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 366.0
TH2_k127_7892334_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 312.0
TH2_k127_7892334_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 294.0
TH2_k127_7892334_15 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001425 271.0
TH2_k127_7892334_16 BON domain K04065 - - 0.000000000000000000000000000000000000000000000000000000000000905 210.0
TH2_k127_7892334_17 - - - - 0.0000000000000000000000000000000000000000000000006961 176.0
TH2_k127_7892334_18 Protein of unknown function (DUF2909) - - - 0.00000000000000000000000004793 108.0
TH2_k127_7892334_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 5.517e-308 945.0
TH2_k127_7892334_20 DDE superfamily endonuclease - - - 0.00000000000005905 71.0
TH2_k127_7892334_21 - - - - 0.00000005289 55.0
TH2_k127_7892334_3 PFAM aminotransferase, class I K14267 - 2.6.1.17 5.415e-253 781.0
TH2_k127_7892334_4 HI0933-like protein K07007 - - 7.406e-232 721.0
TH2_k127_7892334_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 578.0
TH2_k127_7892334_6 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 572.0
TH2_k127_7892334_7 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 566.0
TH2_k127_7892334_8 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 549.0
TH2_k127_7892334_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 440.0
TH2_k127_7966902_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 4.44e-271 836.0
TH2_k127_7966902_1 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 523.0
TH2_k127_7966902_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000001357 224.0
TH2_k127_7966902_3 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000005467 178.0
TH2_k127_7968253_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.0 1120.0
TH2_k127_7968253_1 Signal transduction histidine kinase, phosphotransfer (Hpt) - - - 0.0 1024.0
TH2_k127_7968253_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006571 238.0
TH2_k127_7968253_11 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.00000000000000000000000000000000003826 134.0
TH2_k127_7968253_2 7 transmembrane helices usually fused to an inactive transglutaminase - - - 2.149e-306 942.0
TH2_k127_7968253_3 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 4.077e-275 849.0
TH2_k127_7968253_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 1.64e-200 628.0
TH2_k127_7968253_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 543.0
TH2_k127_7968253_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 510.0
TH2_k127_7968253_7 Sugar-transfer associated ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 497.0
TH2_k127_7968253_8 Putative ATP-dependant zinc protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 457.0
TH2_k127_7968253_9 Universal stress protein K06149 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 291.0
TH2_k127_7977724_0 TIGRFAM type I secretion outer membrane protein, TolC K12538 - - 5.082e-260 804.0
TH2_k127_7977724_1 TIGRFAM Type I secretion membrane fusion protein, HlyD K02022,K12537,K12542 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 576.0
TH2_k127_7985705_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 3.939e-215 670.0
TH2_k127_7985705_1 cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 471.0
TH2_k127_7985705_2 COG3385 FOG Transposase and inactivated derivatives - - - 0.00000000000000000000000000000001177 128.0
TH2_k127_7985705_3 - - - - 0.0000000000000000000006727 109.0
TH2_k127_8020994_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 9.52e-246 770.0
TH2_k127_8020994_1 Metallo-peptidase family M12B Reprolysin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 310.0
TH2_k127_8020994_10 Helix-turn-helix domain - - - 0.0000000000002116 70.0
TH2_k127_8020994_11 PFAM Plasmid stabilisation system K06218 - - 0.0000000000002456 69.0
TH2_k127_8020994_12 PFAM Flp Fap pilin component K02651 - - 0.0000000000002612 71.0
TH2_k127_8020994_13 BNR repeat-like domain - - - 0.0000000001249 63.0
TH2_k127_8020994_15 Transposase and inactivated derivatives - - - 0.00004802 47.0
TH2_k127_8020994_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005933 245.0
TH2_k127_8020994_3 PFAM Helix-turn-helix type 3 - - - 0.000000000000000000000000000000000000000000000000000001256 193.0
TH2_k127_8020994_4 Transposase K07486 - - 0.000000000000000000000000000000000000000000000000000009118 193.0
TH2_k127_8020994_5 TIGRFAM yecA family protein K07039 - - 0.00000000000000000000000000000000000000000000000009606 178.0
TH2_k127_8020994_6 - - - - 0.000000000000000000000000000000000000006386 148.0
TH2_k127_8020994_7 Helix-turn-helix domain K07726 - - 0.0000000000000000000000000000007303 124.0
TH2_k127_8020994_8 COG3316 Transposase and inactivated derivatives K07498 - - 0.000000000000000000004099 93.0
TH2_k127_8020994_9 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000001006 81.0
TH2_k127_8062193_0 ABC transporter K06147,K18893 - - 0.0 1174.0
TH2_k127_8062193_1 TraB family - - - 5.179e-244 756.0
TH2_k127_8062193_2 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008397 517.0
TH2_k127_8062193_3 Putative DNA-binding domain K09929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000012 279.0
TH2_k127_8062193_4 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000004653 171.0
TH2_k127_8062193_5 - - - - 0.00000000000000000000000000000000000000009141 154.0
TH2_k127_8062193_6 2Fe-2S -binding K02192 - - 0.000000000000000000000000000000000004748 138.0
TH2_k127_8062193_7 - - - - 0.00000000000000000000000000000000003086 137.0
TH2_k127_8062193_8 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000001734 65.0
TH2_k127_8073067_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1767.0
TH2_k127_8073067_1 cyanophycin synthetase K03802 - 6.3.2.29,6.3.2.30 0.0 1645.0
TH2_k127_8073067_10 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.072e-222 692.0
TH2_k127_8073067_11 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 5.378e-216 672.0
TH2_k127_8073067_12 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 597.0
TH2_k127_8073067_13 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 593.0
TH2_k127_8073067_14 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 550.0
TH2_k127_8073067_15 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 547.0
TH2_k127_8073067_16 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 523.0
TH2_k127_8073067_17 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 522.0
TH2_k127_8073067_18 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 502.0
TH2_k127_8073067_19 uroporphyrinogen III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 482.0
TH2_k127_8073067_2 cyanophycin synthetase K03802 - 6.3.2.29,6.3.2.30 0.0 1432.0
TH2_k127_8073067_20 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 354.0
TH2_k127_8073067_21 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 346.0
TH2_k127_8073067_22 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 345.0
TH2_k127_8073067_23 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 339.0
TH2_k127_8073067_24 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 319.0
TH2_k127_8073067_25 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 308.0
TH2_k127_8073067_26 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002248 274.0
TH2_k127_8073067_27 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000001958 248.0
TH2_k127_8073067_28 diol metabolic process K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000006663 237.0
TH2_k127_8073067_29 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000008006 230.0
TH2_k127_8073067_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0 1171.0
TH2_k127_8073067_30 PFAM Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000006063 196.0
TH2_k127_8073067_31 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000001214 176.0
TH2_k127_8073067_32 PFAM IstB domain protein ATP-binding protein - - - 0.0002543 44.0
TH2_k127_8073067_4 TIGRFAM Sodium sulphate symporter K11106,K14445 - - 1.312e-269 833.0
TH2_k127_8073067_5 Domain of unknown function DUF21 - - - 4.696e-258 797.0
TH2_k127_8073067_6 PFAM Peptidase M16 K07263 - - 8.483e-258 797.0
TH2_k127_8073067_7 Type II secretion system K02653 - - 1.03e-245 761.0
TH2_k127_8073067_8 Multicopper oxidase K00368,K08100 - 1.3.3.5,1.7.2.1 1.077e-227 707.0
TH2_k127_8073067_9 HemY protein N-terminus K02498 - - 2.045e-226 704.0
TH2_k127_8119669_0 membrane GTPase involved in stress response K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 312.0
TH2_k127_8119669_1 Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000004283 167.0
TH2_k127_8119669_2 PFAM DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000005744 106.0
TH2_k127_8124232_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 6.671e-197 617.0
TH2_k127_8124232_2 - - - - 0.00000000000000000000000000000000000000000000000000000000006914 209.0
TH2_k127_8154831_0 Peptidase family U32 C-terminal domain K08303 - - 1.021e-276 854.0
TH2_k127_8154831_1 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 5.664e-249 771.0
TH2_k127_8154831_2 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069 - - 8.311e-230 713.0
TH2_k127_8154831_3 PFAM alpha beta hydrolase K07019 - - 1.024e-212 662.0
TH2_k127_8154831_4 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 480.0
TH2_k127_8154831_5 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005485 439.0
TH2_k127_8154831_6 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 386.0
TH2_k127_8154831_7 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000001308 218.0
TH2_k127_8171429_0 PFAM Peptidase S45, penicillin amidase K01434 - 3.5.1.11 0.0 1433.0
TH2_k127_8171429_1 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1283.0
TH2_k127_8171429_10 Etoposide-induced protein 2.4 (EI24) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 424.0
TH2_k127_8171429_11 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 384.0
TH2_k127_8171429_12 FlgN protein K02399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004259 269.0
TH2_k127_8171429_13 PFAM Anti-sigma-28 factor, FlgM K02398 - - 0.00000000000000000000000000000000000000000000000000006674 187.0
TH2_k127_8171429_14 Rhodanese Homology Domain - - - 0.00000000000000000002364 91.0
TH2_k127_8171429_2 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase, WcaJ K03606 - - 2.91e-291 897.0
TH2_k127_8171429_3 signal recognition particle SRP54 K02404 - - 2.615e-247 766.0
TH2_k127_8171429_4 Protein conserved in bacteria - - - 6.027e-238 740.0
TH2_k127_8171429_5 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 4.46e-217 677.0
TH2_k127_8171429_6 MotA/TolQ/ExbB proton channel family K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 483.0
TH2_k127_8171429_7 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 479.0
TH2_k127_8171429_8 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 465.0
TH2_k127_8171429_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 461.0
TH2_k127_8256305_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.371e-286 881.0
TH2_k127_8256305_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 2.189e-283 872.0
TH2_k127_8256305_2 Protein of unknown function (DUF3422) - - - 6.258e-257 796.0
TH2_k127_8256305_3 Beta-Casp domain K07576 - - 3.567e-204 636.0
TH2_k127_8256305_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000006194 161.0
TH2_k127_827425_0 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 342.0
TH2_k127_827425_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000001466 180.0
TH2_k127_827425_2 Response regulator, receiver - - - 0.0000001054 55.0
TH2_k127_827990_0 Major Facilitator Superfamily - - - 6.65e-242 750.0
TH2_k127_827990_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 4.28e-199 621.0
TH2_k127_827990_2 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 338.0
TH2_k127_827990_3 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 329.0
TH2_k127_827990_4 Dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000001749 237.0
TH2_k127_827990_5 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000003659 235.0
TH2_k127_8293164_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1628.0
TH2_k127_8293164_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1447.0
TH2_k127_8293164_10 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 3.679e-214 666.0
TH2_k127_8293164_11 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 4.969e-211 658.0
TH2_k127_8293164_12 TIGRFAM glycine oxidase ThiO K03153 - 1.4.3.19 5.458e-210 655.0
TH2_k127_8293164_13 Protein conserved in bacteria - - - 1.943e-205 642.0
TH2_k127_8293164_14 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 1.98e-199 621.0
TH2_k127_8293164_15 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 548.0
TH2_k127_8293164_16 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 460.0
TH2_k127_8293164_17 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 419.0
TH2_k127_8293164_18 Response regulator receiver K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 346.0
TH2_k127_8293164_19 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 301.0
TH2_k127_8293164_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1285.0
TH2_k127_8293164_20 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009302 258.0
TH2_k127_8293164_21 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002054 253.0
TH2_k127_8293164_22 Nacht domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006079 226.0
TH2_k127_8293164_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000002156 216.0
TH2_k127_8293164_24 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000000000000003914 196.0
TH2_k127_8293164_25 - - - - 0.000000000000000000000000000000000000000000000000000002857 192.0
TH2_k127_8293164_26 Nacht domain - - - 0.000000000000000000000000000000000000000000000000000171 186.0
TH2_k127_8293164_27 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000000000000001488 141.0
TH2_k127_8293164_28 - - - - 0.000000000000000000000000000000000001803 141.0
TH2_k127_8293164_29 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000000000003815 79.0
TH2_k127_8293164_3 TonB-dependent Receptor Plug Domain K02014 - - 0.0 1149.0
TH2_k127_8293164_30 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00003292 49.0
TH2_k127_8293164_31 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00003926 48.0
TH2_k127_8293164_4 Putative diguanylate phosphodiesterase - - - 9.715e-289 890.0
TH2_k127_8293164_5 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 2.06e-275 847.0
TH2_k127_8293164_6 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.796e-262 810.0
TH2_k127_8293164_7 Signal transduction histidine kinase K15011 - 2.7.13.3 2.968e-257 795.0
TH2_k127_8293164_8 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 7.901e-255 788.0
TH2_k127_8293164_9 DAHP synthetase I family K03856 - 2.5.1.54 2.666e-241 746.0
TH2_k127_8314120_0 May be involved in recombinational repair of damaged DNA K03631 - - 1.285e-310 958.0
TH2_k127_8314120_1 Signal transduction histidine kinase K07637 - 2.7.13.3 1.159e-265 821.0
TH2_k127_8314120_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 1.054e-233 723.0
TH2_k127_8314120_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 1.305e-204 638.0
TH2_k127_8314120_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 578.0
TH2_k127_8314120_5 PFAM Signal transduction response regulator, receiver K07660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 437.0
TH2_k127_8314120_6 Small metal-binding protein - - - 0.00000000000000000000000000000000000000000000000000000001496 199.0
TH2_k127_8314120_7 peptidase - - - 0.00000000000000000000000000000000000000000000001131 171.0
TH2_k127_8314120_8 membrane - - - 0.000000000000000000000000000000000000000000008462 163.0
TH2_k127_8314120_9 - - - - 0.0000000000000000000000000000000000000000004491 161.0
TH2_k127_8366969_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0 1448.0
TH2_k127_8366969_1 Tex-like protein N-terminal domain K06959 - - 0.0 1396.0
TH2_k127_8366969_10 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 1.65e-219 683.0
TH2_k127_8366969_11 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 7.964e-213 663.0
TH2_k127_8366969_12 May be involved in recombination K03554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 577.0
TH2_k127_8366969_13 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 554.0
TH2_k127_8366969_14 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 528.0
TH2_k127_8366969_15 MobA-like NTP transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 509.0
TH2_k127_8366969_16 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 497.0
TH2_k127_8366969_17 two-component system sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 475.0
TH2_k127_8366969_18 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 460.0
TH2_k127_8366969_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 447.0
TH2_k127_8366969_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1201.0
TH2_k127_8366969_20 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 411.0
TH2_k127_8366969_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 404.0
TH2_k127_8366969_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 400.0
TH2_k127_8366969_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 308.0
TH2_k127_8366969_24 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 299.0
TH2_k127_8366969_25 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003206 265.0
TH2_k127_8366969_26 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003385 259.0
TH2_k127_8366969_27 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009621 255.0
TH2_k127_8366969_28 RDD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002377 256.0
TH2_k127_8366969_29 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003402 247.0
TH2_k127_8366969_3 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1193.0
TH2_k127_8366969_30 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007877 250.0
TH2_k127_8366969_31 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000000000000000000000000000000000001286 225.0
TH2_k127_8366969_32 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000261 224.0
TH2_k127_8366969_33 Domain of unknown function (DUF5062) - - - 0.00000000000000000000000000000000000000000000003547 170.0
TH2_k127_8366969_34 Universal stress protein family - - - 0.000000000000000000000000000000001345 134.0
TH2_k127_8366969_35 Methyltransferase domain - - - 0.000000000000000000000000000001438 123.0
TH2_k127_8366969_36 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000000000001823 119.0
TH2_k127_8366969_37 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000006011 115.0
TH2_k127_8366969_38 Nucleotidyltransferase domain - - - 0.0000000000000000000001197 102.0
TH2_k127_8366969_39 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000005131 94.0
TH2_k127_8366969_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 2.325e-310 953.0
TH2_k127_8366969_40 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000002615 82.0
TH2_k127_8366969_41 PFAM Permease YjgP YjgQ K07091 - - 0.000000000001163 68.0
TH2_k127_8366969_5 PFAM peptidase - - - 3.85e-283 871.0
TH2_k127_8366969_6 AAA C-terminal domain K07478 - - 9.497e-271 839.0
TH2_k127_8366969_7 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 7.565e-269 830.0
TH2_k127_8366969_8 Sulfate permease family - - - 1.999e-235 734.0
TH2_k127_8366969_9 acetyltransferase - - - 2.554e-224 699.0
TH2_k127_8370784_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1858.0
TH2_k127_8370784_1 Sugar (and other) transporter - - - 3.981e-262 811.0
TH2_k127_8370784_10 - - - - 0.00000000000000000000000000000286 120.0
TH2_k127_8370784_11 Hemin uptake protein hemP - - - 0.00000000000000000000008162 99.0
TH2_k127_8370784_12 - - - - 0.0000000000000000000006186 96.0
TH2_k127_8370784_2 MOFRL family K11529 - 2.7.1.165 4.105e-240 747.0
TH2_k127_8370784_3 PFAM Heat shock protein DnaJ, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 593.0
TH2_k127_8370784_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 566.0
TH2_k127_8370784_5 Uncharacterized protein conserved in bacteria (DUF2325) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 346.0
TH2_k127_8370784_6 Iron-storage protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 309.0
TH2_k127_8370784_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 290.0
TH2_k127_8370784_8 Protein of unknown function (DUF2806) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004076 255.0
TH2_k127_8370784_9 transporter component K07112 - - 0.00000000000000000000000000000000004349 136.0
TH2_k127_8384786_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1839.0
TH2_k127_8384786_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 7.195e-292 899.0
TH2_k127_8384786_10 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 301.0
TH2_k127_8384786_11 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 291.0
TH2_k127_8384786_12 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 282.0
TH2_k127_8384786_13 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001836 273.0
TH2_k127_8384786_14 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000000000000000003173 172.0
TH2_k127_8384786_15 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000000000004765 161.0
TH2_k127_8384786_16 - - - - 0.000000000000000000000006149 102.0
TH2_k127_8384786_17 - - - - 0.00000000009036 62.0
TH2_k127_8384786_18 DDE superfamily endonuclease K07494 - - 0.000000003651 59.0
TH2_k127_8384786_19 pathogenesis K01119 - 3.1.3.6,3.1.4.16 0.0000006066 51.0
TH2_k127_8384786_2 Peptidase family M23 - - - 9.237e-226 704.0
TH2_k127_8384786_20 - - - - 0.000008247 51.0
TH2_k127_8384786_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 606.0
TH2_k127_8384786_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 585.0
TH2_k127_8384786_5 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 486.0
TH2_k127_8384786_6 UBA THIF-type NAD FAD binding K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 444.0
TH2_k127_8384786_7 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 363.0
TH2_k127_8384786_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 314.0
TH2_k127_8384786_9 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 311.0
TH2_k127_8508532_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 443.0
TH2_k127_8508532_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 409.0
TH2_k127_8508532_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 307.0
TH2_k127_8508532_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 291.0
TH2_k127_8508532_4 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001403 273.0
TH2_k127_8508532_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000001675 115.0
TH2_k127_859272_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 500.0
TH2_k127_859272_1 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000001695 163.0
TH2_k127_859272_2 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000000006257 123.0
TH2_k127_859272_3 Protein of unknown function DUF86 - - - 0.00000000000000000000000000005784 119.0
TH2_k127_859272_4 - - - - 0.000001232 50.0
TH2_k127_859272_5 Periplasmic protein - - - 0.00007083 53.0
TH2_k127_8702713_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1840.0
TH2_k127_8702713_1 malic enzyme K00029 - 1.1.1.40 0.0 1024.0
TH2_k127_8702713_10 Universal stress protein - - - 0.0000000000000000000000000000000000000001824 150.0
TH2_k127_8702713_11 Belongs to the 'phage' integrase family - - - 0.000000007035 57.0
TH2_k127_8702713_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 5.485e-307 943.0
TH2_k127_8702713_3 Cache domain - - - 2.065e-299 924.0
TH2_k127_8702713_4 TIGRFAM Diguanylate cyclase - - - 1.307e-292 901.0
TH2_k127_8702713_5 TIGRFAM Phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 481.0
TH2_k127_8702713_6 PFAM SH3, type 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 406.0
TH2_k127_8702713_7 COG2346, Truncated hemoglobins K06886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001014 269.0
TH2_k127_8702713_8 DNA polymerase III (Chi subunit) K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000002806 256.0
TH2_k127_8702713_9 - - - - 0.000000000000000000000000000000000000000000000000005882 183.0
TH2_k127_8716054_0 Heavy metal transport detoxification protein K17686,K19597 - 3.6.3.54 0.0 1416.0
TH2_k127_8716054_1 Lipocalin-like domain - - - 7.135e-233 722.0
TH2_k127_8716054_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000000000000000000000000000003018 186.0
TH2_k127_8716054_11 PFAM Heavy metal transport detoxification protein K07213 - - 0.000000000000000000000000000000004586 128.0
TH2_k127_8716054_12 - - - - 0.000000000002573 66.0
TH2_k127_8716054_2 FtsX-like permease family K02004 - - 4.111e-210 655.0
TH2_k127_8716054_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 489.0
TH2_k127_8716054_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 364.0
TH2_k127_8716054_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 319.0
TH2_k127_8716054_6 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000007649 244.0
TH2_k127_8716054_7 HIT domain K02503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006379 237.0
TH2_k127_8716054_8 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000002497 211.0
TH2_k127_8716054_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000000000000000000000000000000000001494 192.0
TH2_k127_8770656_0 SMART ATPase, AAA type, core K06158 - - 0.0 1132.0
TH2_k127_8770656_1 response regulator K10943 - - 1.748e-251 779.0
TH2_k127_8770656_2 Signal transduction histidine kinase K10942 - 2.7.13.3 1.587e-233 725.0
TH2_k127_8770656_3 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 417.0
TH2_k127_8770656_4 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000000000000000000000000000000000000000000000006191 191.0
TH2_k127_8856112_0 Bacterial regulatory helix-turn-helix protein, lysR family K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 392.0
TH2_k127_8856112_1 Subtilase family - - - 0.00000000000000000000000000000044 141.0
TH2_k127_8856112_2 TRAG family K03205 - - 0.00000000000000000005648 90.0
TH2_k127_905950_0 Response regulator receiver K02487,K03407,K06596 - 2.7.13.3 0.0 2378.0
TH2_k127_905950_1 PFAM chemotaxis K02660 - - 0.0 1197.0
TH2_k127_905950_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.0 999.0
TH2_k127_905950_3 ABC transporter K06147 - - 5.981e-284 874.0
TH2_k127_905950_4 Domain of unknown function (DUF1854) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 291.0
TH2_k127_906210_0 Competence protein ComEC Rec2 K02238 - - 0.0 1432.0
TH2_k127_906210_1 PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase K13924 - 2.1.1.80,3.1.1.61 8.662e-255 788.0
TH2_k127_906210_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 533.0
TH2_k127_918841_0 Insecticidal toxin complex protein TcaC - - - 0.0 1856.0
TH2_k127_93975_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1889.0
TH2_k127_93975_1 Belongs to the peptidase S16 family - - - 0.0 1510.0
TH2_k127_93975_10 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 349.0
TH2_k127_93975_11 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002348 268.0
TH2_k127_93975_12 Universal stress protein family - - - 0.00000000000000000000000000000000003556 139.0
TH2_k127_93975_2 PFAM Multicopper oxidase, type - - - 0.0 1113.0
TH2_k127_93975_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0 1071.0
TH2_k127_93975_4 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - - 4.085e-247 766.0
TH2_k127_93975_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 1.418e-231 717.0
TH2_k127_93975_6 Sulfate permease family - - - 2.891e-208 657.0
TH2_k127_93975_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18094 - - 4.296e-206 647.0
TH2_k127_93975_8 PFAM multicopper oxidase type 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 597.0
TH2_k127_93975_9 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 505.0
TH2_k127_98728_0 Alginate export - - - 6.048e-288 885.0
TH2_k127_98728_2 - - - - 0.00000006132 53.0