logo

Overview

ID MAG03926
Name TH2_bin.68
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Verrucomicrobiota
Class Kiritimatiellia
Order UBA8416
Family VGWI01
Genus
Species
Assembly information
Completeness (%) 63.47
Contamination (%) 1.61
GC content (%) 68.0
N50 (bp) 5,162
Genome size (bp) 2,440,280

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1964

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1012332_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 574.0
TH2_k127_1012332_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002246 266.0
TH2_k127_1012332_2 PFAM Protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000001436 231.0
TH2_k127_1012332_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000002199 175.0
TH2_k127_1016570_0 Endoribonuclease that initiates mRNA decay K18682 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 523.0
TH2_k127_1016570_1 AAA ATPase central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 477.0
TH2_k127_1016570_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 412.0
TH2_k127_1016570_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 340.0
TH2_k127_1016570_4 metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 298.0
TH2_k127_1016570_5 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003461 277.0
TH2_k127_1016570_6 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000004368 126.0
TH2_k127_1016570_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000006352 68.0
TH2_k127_102223_0 sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 391.0
TH2_k127_102223_1 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 379.0
TH2_k127_102223_2 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 312.0
TH2_k127_102223_3 PFAM Pyruvoyl-dependent arginine decarboxylase K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000009653 231.0
TH2_k127_102223_4 Caspase domain - - - 0.0000002981 59.0
TH2_k127_102223_5 Polysaccharide biosynthesis protein - - - 0.00001289 53.0
TH2_k127_1037077_0 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 361.0
TH2_k127_1037077_1 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000003369 199.0
TH2_k127_1037077_2 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000000005837 135.0
TH2_k127_1037077_3 Regulatory protein, FmdB family - - - 0.000000000000000000000004324 106.0
TH2_k127_1037077_4 bacteriocin transport K03561 - - 0.000000000000000000001107 106.0
TH2_k127_1039653_0 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity K02535,K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 312.0
TH2_k127_1039653_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000005118 218.0
TH2_k127_1039653_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000002118 139.0
TH2_k127_1039653_3 Transcriptional regulator - - - 0.00000000000000000000000000000000007295 138.0
TH2_k127_1039653_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000002328 119.0
TH2_k127_1048826_0 MGS-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 302.0
TH2_k127_1048826_1 PHP domain protein K01624,K07053 - 3.1.3.97,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000002175 242.0
TH2_k127_1048826_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000002809 128.0
TH2_k127_1048826_3 synthase K06175 - 5.4.99.26 0.0000000000000000000007096 100.0
TH2_k127_1048826_4 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 0.00000000000005835 79.0
TH2_k127_107651_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 336.0
TH2_k127_107651_1 lipoprotein transporter activity K02003,K05685,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003866 258.0
TH2_k127_107651_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072,K11076 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000001013 216.0
TH2_k127_107651_3 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000148 179.0
TH2_k127_107651_4 - - - - 0.000000000000000000000000000000000000000000004612 185.0
TH2_k127_107651_5 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000005392 150.0
TH2_k127_107651_6 Parallel beta-helix repeats - - - 0.0000000000000000000000000002928 128.0
TH2_k127_107651_7 Bacterial extracellular solute-binding protein K10938 - - 0.000000000000000000005216 104.0
TH2_k127_107651_8 Bacterial extracellular solute-binding protein K02020 - - 0.000000006442 69.0
TH2_k127_107651_9 Sulfatase-modifying factor enzyme 1 - - - 0.0008329 48.0
TH2_k127_10805_0 Belongs to the Nudix hydrolase family. NudC subfamily K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 306.0
TH2_k127_10805_1 methyltransferase - - - 0.0000000000000000001676 101.0
TH2_k127_1087726_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001532 289.0
TH2_k127_1087726_1 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000001215 169.0
TH2_k127_1108156_0 Polysaccharide biosynthesis protein CapD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 400.0
TH2_k127_1108156_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000008766 165.0
TH2_k127_1108156_2 PFAM PIN domain - - - 0.000000000000000000000000000000002318 133.0
TH2_k127_1108156_3 copG family - - - 0.000000000000002961 77.0
TH2_k127_1129883_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0 1207.0
TH2_k127_1129883_1 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 425.0
TH2_k127_1129883_2 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000003136 193.0
TH2_k127_1129883_3 Transposase IS200 like - - - 0.0000000000000000000114 100.0
TH2_k127_1137146_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000002849 202.0
TH2_k127_1137146_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000757 164.0
TH2_k127_1137945_0 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001919 303.0
TH2_k127_1137945_1 Pfam Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000001698 68.0
TH2_k127_1149941_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0000000000000000000000000005279 132.0
TH2_k127_1157302_0 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 338.0
TH2_k127_1157302_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000003553 60.0
TH2_k127_1160996_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 332.0
TH2_k127_1160996_1 Elongator protein 3, MiaB family, Radical SAM K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 327.0
TH2_k127_1160996_10 cobalamin binding - - - 0.000000000000000000000002551 106.0
TH2_k127_1160996_11 fibronectin type III domain protein - - - 0.000000000000000000000003039 118.0
TH2_k127_1160996_12 PFAM Nitroreductase - - - 0.000000000000000000001591 107.0
TH2_k127_1160996_13 Phosphopantetheine attachment site - - - 0.00000000000001217 86.0
TH2_k127_1160996_14 COG0110 Acetyltransferase (isoleucine patch superfamily) K00661 - 2.3.1.79 0.00000000000005505 79.0
TH2_k127_1160996_15 methyltransferase activity - - - 0.00000000000009771 82.0
TH2_k127_1160996_16 ubiE/COQ5 methyltransferase family - - - 0.0000000000001708 82.0
TH2_k127_1160996_17 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000004512 76.0
TH2_k127_1160996_18 cobalamin binding - - - 0.0000000009285 67.0
TH2_k127_1160996_19 HEAT repeats - - - 0.00008669 54.0
TH2_k127_1160996_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 317.0
TH2_k127_1160996_20 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K21789 - 2.3.1.179 0.0001128 53.0
TH2_k127_1160996_3 PFAM Radical SAM K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 309.0
TH2_k127_1160996_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 302.0
TH2_k127_1160996_5 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000008178 229.0
TH2_k127_1160996_6 Enoyl-(Acyl carrier protein) reductase K00034,K03366 - 1.1.1.304,1.1.1.47,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000006572 215.0
TH2_k127_1160996_7 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000003548 194.0
TH2_k127_1160996_8 Radical SAM - - - 0.00000000000000000000000000000000000000004303 174.0
TH2_k127_1160996_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000003433 124.0
TH2_k127_1162550_0 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 492.0
TH2_k127_1162550_1 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 321.0
TH2_k127_1162550_2 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000057 141.0
TH2_k127_1162550_3 - - - - 0.00000000000000004869 88.0
TH2_k127_1170854_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000003686 220.0
TH2_k127_1170854_1 Polysaccharide deacetylase K01452,K14659,K22278 - 3.5.1.104,3.5.1.41 0.0000000000000000000000000000000000000000000000000000008706 213.0
TH2_k127_1170854_2 HEPN domain K09132 - - 0.00000000000111 75.0
TH2_k127_1170854_3 Nucleotidyltransferase domain K07076 - - 0.00000006699 59.0
TH2_k127_1189636_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 312.0
TH2_k127_1189636_1 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 302.0
TH2_k127_1199862_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 560.0
TH2_k127_1199862_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000001586 130.0
TH2_k127_1203611_0 Putative Fe-S cluster K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 624.0
TH2_k127_1203611_1 protein histidine kinase activity K02484,K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 303.0
TH2_k127_1203611_2 toxin-antitoxin pair type II binding K08591,K19159 - 2.3.1.15 0.00000000000000000000000008308 108.0
TH2_k127_1203611_3 response regulator, receiver - - - 0.000000000000000000000003399 108.0
TH2_k127_1203611_4 helix_turn_helix, arabinose operon control protein - - - 0.000000000000007677 79.0
TH2_k127_1203611_5 iron hydrogenase, small subunit K00336,K18332 - 1.12.1.3,1.6.5.3 0.0000000000005705 70.0
TH2_k127_1203611_6 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0001267 49.0
TH2_k127_1216886_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 317.0
TH2_k127_1216886_1 Acid phosphatase homologues - - - 0.00000000000000000000000000000000471 139.0
TH2_k127_1216886_2 PFAM Rhomboid family protein - - - 0.000000008755 60.0
TH2_k127_1219221_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 1.091e-258 809.0
TH2_k127_1219221_1 iron-sulfur cluster assembly K00336,K18332 - 1.12.1.3,1.6.5.3 5.206e-249 780.0
TH2_k127_1219221_2 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000009103 151.0
TH2_k127_1219221_3 cheY-homologous receiver domain K07658 - - 0.000000000000000000000000000000000004171 143.0
TH2_k127_1219221_4 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000000000000002322 135.0
TH2_k127_1228092_0 Domain of unknown function DUF128 K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008719 284.0
TH2_k127_1228092_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001251 246.0
TH2_k127_1228092_2 Belongs to the phosphoglycerate mutase family K02226,K22305 - 3.1.3.3,3.1.3.73 0.000001348 59.0
TH2_k127_1232571_0 Methyltransferase domain K18896 - 2.1.1.156 0.0000000000000000000000000000000000000000000000000000000000000000000001641 247.0
TH2_k127_1232571_1 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007561 245.0
TH2_k127_1232933_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 493.0
TH2_k127_1232933_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 444.0
TH2_k127_1232933_2 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term K17108 - 3.2.1.45 0.00000000000000000000001012 116.0
TH2_k127_1232933_3 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 0.000000000000001477 83.0
TH2_k127_1237459_0 Oxidoreductase FAD-binding domain K00351 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 315.0
TH2_k127_1237459_1 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 294.0
TH2_k127_1237459_2 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000002604 134.0
TH2_k127_1237459_3 PFAM glycoside hydrolase, family 13 domain protein - - - 0.0000000000000000000006507 98.0
TH2_k127_1237459_4 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.00000000000001209 77.0
TH2_k127_1237459_5 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.00000000001301 73.0
TH2_k127_1237459_6 Histidine kinase K02480 - 2.7.13.3 0.00000006098 57.0
TH2_k127_126225_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000005206 199.0
TH2_k127_126225_1 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0002263 53.0
TH2_k127_1288197_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 358.0
TH2_k127_1288197_1 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000007118 246.0
TH2_k127_1288197_2 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000005246 128.0
TH2_k127_1323167_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1211.0
TH2_k127_1344515_0 PFAM Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 419.0
TH2_k127_1344515_1 PFAM IstB-like ATP binding protein - - - 0.000000000000000000000000000000002942 132.0
TH2_k127_1347579_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 589.0
TH2_k127_1347579_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 484.0
TH2_k127_1347579_2 ABC transporter K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 433.0
TH2_k127_1347579_3 AraC-like ligand binding domain K02854 - - 0.000000000000000000000000000000000000000000000000000000000000000000001434 246.0
TH2_k127_1347579_4 lipolytic protein G-D-S-L family - - - 0.000001965 61.0
TH2_k127_135463_0 COG1520 FOG WD40-like repeat - - - 0.00000000006626 75.0
TH2_k127_1361508_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000004894 201.0
TH2_k127_1361508_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000544 183.0
TH2_k127_1376849_0 tagaturonate epimerase K21619 - 5.1.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 513.0
TH2_k127_1376849_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 362.0
TH2_k127_1376849_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K16924 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000008356 207.0
TH2_k127_1376849_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000008941 197.0
TH2_k127_1376849_4 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000114 171.0
TH2_k127_1376849_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000035 143.0
TH2_k127_1376849_6 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.00004824 51.0
TH2_k127_1387143_0 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000005579 150.0
TH2_k127_1387143_1 Transposase IS200 like - - - 0.00000000000000000000000000000001304 133.0
TH2_k127_1398998_0 PQQ-like domain - - - 0.000008073 58.0
TH2_k127_1411556_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 7.693e-229 724.0
TH2_k127_1411556_1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 447.0
TH2_k127_1411556_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 416.0
TH2_k127_1411556_3 Metallopeptidase family M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000002226 256.0
TH2_k127_1424975_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 434.0
TH2_k127_1424975_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009735 261.0
TH2_k127_1424975_2 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000001983 235.0
TH2_k127_1424975_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000009529 191.0
TH2_k127_1424975_4 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000001001 173.0
TH2_k127_1424975_5 MlaD protein K02067 - - 0.000000000000000000000000000000000000000001155 171.0
TH2_k127_1424975_6 ATP synthase subunit K K02124 - - 0.000000000000000000000000000000000000005078 153.0
TH2_k127_1424975_7 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000004862 153.0
TH2_k127_1452162_0 Acetyl xylan esterase (AXE1) K01060 - 3.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 501.0
TH2_k127_1452162_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000001165 154.0
TH2_k127_1452162_2 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.00000000000000000000354 109.0
TH2_k127_1465821_0 Alpha-L-fucosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001495 286.0
TH2_k127_1465821_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000007556 53.0
TH2_k127_1476813_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 401.0
TH2_k127_1476813_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000003315 180.0
TH2_k127_1476813_2 Riboflavin biosynthesis protein RibD K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000115 147.0
TH2_k127_1476813_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000001359 123.0
TH2_k127_147682_0 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008546 237.0
TH2_k127_147682_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000004979 191.0
TH2_k127_147682_2 Memo-like protein - - - 0.00000000000000000000000000000000008528 147.0
TH2_k127_147682_3 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000000000009631 134.0
TH2_k127_147682_4 Kdo2-lipid A biosynthetic process K02517,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000000000000107 134.0
TH2_k127_1485949_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 341.0
TH2_k127_1485949_1 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 307.0
TH2_k127_1491443_0 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008832 416.0
TH2_k127_1491443_1 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 371.0
TH2_k127_1491443_2 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000005404 245.0
TH2_k127_1491443_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000001845 102.0
TH2_k127_1500516_0 PFAM Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 424.0
TH2_k127_1500516_1 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000138 258.0
TH2_k127_1536959_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.00000000000000000007846 105.0
TH2_k127_1554038_0 Rhodanese Homology Domain K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 561.0
TH2_k127_1554038_1 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 512.0
TH2_k127_1554038_2 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000002155 212.0
TH2_k127_1554766_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1057.0
TH2_k127_1554766_1 PFAM aminotransferase, class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 307.0
TH2_k127_1554766_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 297.0
TH2_k127_1554766_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000002427 203.0
TH2_k127_1554766_4 PFAM UvrB UvrC protein K08999 - - 0.000000000000000000000000000000001224 137.0
TH2_k127_1554766_5 PFAM Sodium hydrogen exchanger family - - - 0.000000000000000000000000000000006906 133.0
TH2_k127_1554766_6 Polysaccharide biosynthesis protein - - - 0.00000000001446 74.0
TH2_k127_1592159_0 PFAM type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000182 151.0
TH2_k127_1647402_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 367.0
TH2_k127_1647402_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000001217 247.0
TH2_k127_1654289_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 359.0
TH2_k127_1654289_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002719 244.0
TH2_k127_1654289_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000001393 134.0
TH2_k127_1658015_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001127 284.0
TH2_k127_1658015_1 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000002208 229.0
TH2_k127_1707507_0 Protein of unknown function, DUF255 K06888 - - 6.387e-235 743.0
TH2_k127_1707507_1 PFAM Glutamine synthetase, catalytic K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 557.0
TH2_k127_1707507_2 SOUL heme-binding protein - - - 0.000000000004459 72.0
TH2_k127_1709136_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 3.359e-202 641.0
TH2_k127_1709136_1 DNA-directed DNA polymerase K02337 - 2.7.7.7 7.963e-195 627.0
TH2_k127_1709136_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009708 591.0
TH2_k127_1709136_3 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 537.0
TH2_k127_1709136_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 432.0
TH2_k127_1709136_5 PFAM Divergent PAP2 family K09775 - - 0.000000000000000000000000000000000001439 145.0
TH2_k127_1709136_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000101 129.0
TH2_k127_1709136_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0002488 47.0
TH2_k127_1729896_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1395.0
TH2_k127_1729896_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 1.081e-291 913.0
TH2_k127_1729896_10 2 iron, 2 sulfur cluster binding K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000003128 222.0
TH2_k127_1729896_11 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000001586 231.0
TH2_k127_1729896_12 Mo-molybdopterin cofactor metabolic process K02379,K18360 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0043085,GO:0043546,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050790,GO:0065007,GO:0065009,GO:0097159,GO:0097163,GO:0140104,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000001208 214.0
TH2_k127_1729896_13 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000004217 150.0
TH2_k127_1729896_14 sequence-specific DNA binding - - - 0.0000000000000000002959 96.0
TH2_k127_1729896_16 - - - - 0.00000000000004552 81.0
TH2_k127_1729896_17 Predicted RNA-binding protein - - - 0.000000000031 66.0
TH2_k127_1729896_2 CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 5.595e-280 878.0
TH2_k127_1729896_3 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 7.116e-211 678.0
TH2_k127_1729896_4 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 584.0
TH2_k127_1729896_5 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 529.0
TH2_k127_1729896_6 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 436.0
TH2_k127_1729896_7 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 416.0
TH2_k127_1729896_8 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007128 265.0
TH2_k127_1729896_9 Methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000001954 244.0
TH2_k127_1729980_0 Pyridine nucleotide-disulphide oxidoreductase K00335 - 1.6.5.3 0.0 1349.0
TH2_k127_1729980_1 PFAM Iron only hydrogenase large subunit, C-terminal domain K00336,K18332,K22015 - 1.12.1.3,1.17.99.7,1.6.5.3 1.48e-224 708.0
TH2_k127_1729980_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000005098 216.0
TH2_k127_1729980_3 2 iron, 2 sulfur cluster binding K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000004793 212.0
TH2_k127_1745904_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.00000000000000000000000000000000004783 152.0
TH2_k127_1745904_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000008952 98.0
TH2_k127_1809733_0 beta-galactosidase activity K01190,K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000002953 248.0
TH2_k127_182675_0 PFAM phosphoesterase RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000006019 218.0
TH2_k127_182675_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000562 201.0
TH2_k127_182675_2 Methyltransferase domain K01935,K02169 - 2.1.1.197,6.3.3.3 0.00000000000000000000000000000000000000001553 171.0
TH2_k127_182675_3 Protein of unknown function (DUF452) K09789 - 3.1.1.85 0.00000000000000000000000000006237 127.0
TH2_k127_182675_4 PFAM aminotransferase, class I and II K00652 - 2.3.1.47 0.000000000000000462 79.0
TH2_k127_1876360_0 Leucine-rich repeats, outliers - - - 0.0000000001556 73.0
TH2_k127_1892466_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 474.0
TH2_k127_1892466_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 287.0
TH2_k127_1892466_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000482 142.0
TH2_k127_1914_0 Large extracellular alpha-helical protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003296 281.0
TH2_k127_1914_1 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005305 247.0
TH2_k127_1914_2 DNA-binding transcription factor activity K03710 - - 0.000000000000000000001506 107.0
TH2_k127_1983147_0 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 333.0
TH2_k127_1983147_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 0.00000000000000000000000000000000000000000000003871 178.0
TH2_k127_1983147_2 Transglutaminase/protease-like homologues - - - 0.0001198 51.0
TH2_k127_1985116_0 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000002601 114.0
TH2_k127_1985116_1 Family of unknown function (DUF5362) - - - 0.00000000000000007468 89.0
TH2_k127_1985116_2 ATP synthase delta (OSCP) subunit K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000152 55.0
TH2_k127_2009928_0 Glycosyl hydrolases family 35 - - - 0.0000000000000000000000000000000000000000000000000000000001069 229.0
TH2_k127_2009928_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000001086 176.0
TH2_k127_2052535_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000004835 236.0
TH2_k127_2052535_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000003563 140.0
TH2_k127_205955_0 Forkhead associated domain K01990,K21397 - - 0.00000000000000000003474 104.0
TH2_k127_2060023_0 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 416.0
TH2_k127_2060023_1 Belongs to the glycosyl hydrolase 28 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 347.0
TH2_k127_2060023_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 306.0
TH2_k127_2118752_0 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 351.0
TH2_k127_2118752_1 - - - - 0.0000000001399 70.0
TH2_k127_2118752_2 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.00000006689 60.0
TH2_k127_2118752_3 - - - - 0.0001579 50.0
TH2_k127_212243_0 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 420.0
TH2_k127_212243_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 351.0
TH2_k127_212243_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002947 266.0
TH2_k127_212243_3 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000001079 242.0
TH2_k127_212243_4 nuclear chromosome segregation - - - 0.0000000000000000000000002335 122.0
TH2_k127_212243_5 PQQ-like domain - - - 0.0006722 53.0
TH2_k127_214294_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000006504 181.0
TH2_k127_214294_1 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000007279 155.0
TH2_k127_215524_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000001442 150.0
TH2_k127_215524_1 beta-galactosidase K12308 - 3.2.1.23 0.0000000007394 63.0
TH2_k127_215524_2 dioxygenase activity K03183,K04040 - 2.1.1.163,2.1.1.201,2.5.1.133,2.5.1.62 0.0001327 53.0
TH2_k127_218005_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000008395 210.0
TH2_k127_218005_1 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000006695 173.0
TH2_k127_218005_2 - - - - 0.00000000000000002855 97.0
TH2_k127_2212351_0 - - - - 0.0000000000000000000000000000000000000008669 173.0
TH2_k127_2212351_1 PQQ-like domain - - - 0.000000001901 72.0
TH2_k127_2213188_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000006127 194.0
TH2_k127_2213188_1 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000005403 140.0
TH2_k127_2213188_3 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000005507 81.0
TH2_k127_2213188_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000001449 77.0
TH2_k127_2213188_5 PQQ-like domain - - - 0.0000002053 64.0
TH2_k127_2232421_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 483.0
TH2_k127_2232421_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006964 279.0
TH2_k127_2265936_0 Chain length determinant protein - - - 0.000000001591 68.0
TH2_k127_2265936_1 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00001857 51.0
TH2_k127_2270566_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 293.0
TH2_k127_2270566_1 KR domain K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000001685 189.0
TH2_k127_2270566_2 KR domain K00059,K18337 - 1.1.1.100,1.1.1.173,1.1.1.377,1.1.1.378 0.0000000000000000000000000000000000000000000000001565 188.0
TH2_k127_2270566_3 cobalamin binding - - - 0.0000000000000000000000000000000000000000001233 182.0
TH2_k127_2270566_4 Xylose isomerase-like TIM barrel K22233 - - 0.0000000008459 68.0
TH2_k127_2290155_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 7.912e-253 792.0
TH2_k127_2290155_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366,K00392 - 1.7.7.1,1.8.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 512.0
TH2_k127_2290155_10 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000000000001647 151.0
TH2_k127_2290155_11 NADH-quinone oxidoreductase, E subunit K00334,K18330,K22340 - 1.12.1.3,1.17.1.11,1.6.5.3 0.00000000000000000000000000000000000005671 161.0
TH2_k127_2290155_12 DNA photolyase activity K03716 GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0005575,GO:0005623,GO:0016829,GO:0016830,GO:0042601,GO:0042763,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070283,GO:0140097 4.1.99.14 0.0000000000000000000000000000000000001356 155.0
TH2_k127_2290155_13 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.00000000000000000000000000000000005323 138.0
TH2_k127_2290155_14 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 - 1.6.5.8 0.0000000000000000000000000000002793 140.0
TH2_k127_2290155_15 SMART Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.000000000000000000000000000004903 123.0
TH2_k127_2290155_16 DRTGG domain - - - 0.000000000000000000000000001436 115.0
TH2_k127_2290155_17 DRTGG domain - - - 0.000000000000000000000000001919 115.0
TH2_k127_2290155_18 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.8 0.00000000000000000000000005695 116.0
TH2_k127_2290155_19 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000732 101.0
TH2_k127_2290155_2 PFAM UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 355.0
TH2_k127_2290155_20 thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000000369 83.0
TH2_k127_2290155_21 PFAM response regulator receiver K07659,K11329 - - 0.00000000000009113 78.0
TH2_k127_2290155_22 TIGRFAM autotransporter-associated beta strand repeat protein - - - 0.00000000032 74.0
TH2_k127_2290155_23 Involved in the TonB-independent uptake of proteins K03641 - - 0.00002561 58.0
TH2_k127_2290155_3 Part of a membrane complex involved in electron transport K00347 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 315.0
TH2_k127_2290155_4 PFAM ATP-binding region, ATPase domain protein K17752 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001244 282.0
TH2_k127_2290155_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002302 262.0
TH2_k127_2290155_6 Rnf-Nqr subunit, membrane protein K00350 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000573 213.0
TH2_k127_2290155_7 PHP-associated K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000001498 211.0
TH2_k127_2290155_8 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000003683 209.0
TH2_k127_2290155_9 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000003724 196.0
TH2_k127_2302723_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.96e-265 827.0
TH2_k127_2302723_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 429.0
TH2_k127_2302723_2 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000000000000000002123 121.0
TH2_k127_2314352_0 PQQ-like domain K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 435.0
TH2_k127_2314352_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000009941 173.0
TH2_k127_2318849_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 336.0
TH2_k127_2318849_1 mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 297.0
TH2_k127_2318849_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000006986 205.0
TH2_k127_2338451_0 Transketolase, pyrimidine binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 580.0
TH2_k127_2338451_1 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 369.0
TH2_k127_2338451_2 PFAM short-chain dehydrogenase reductase SDR K00059,K03793 - 1.1.1.100,1.5.1.33 0.0000000000000000000000000000000000000000000000000000001746 206.0
TH2_k127_2338451_3 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.000000000000000000000000000000000000000000003431 186.0
TH2_k127_2338451_4 OsmC-like protein - - - 0.00000000000000000000000000000000000006248 151.0
TH2_k127_2338451_6 Sensory domain found in PocR - - - 0.0000000000002387 79.0
TH2_k127_2339802_0 B12 binding domain K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 472.0
TH2_k127_2339802_1 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 426.0
TH2_k127_2339802_2 lipid A biosynthesis acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000122 271.0
TH2_k127_2339802_3 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000916 249.0
TH2_k127_2339802_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000002331 226.0
TH2_k127_2339802_5 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.000000000000000000000000000000000000000000000000001417 208.0
TH2_k127_2339802_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000002326 88.0
TH2_k127_235052_0 COG1894 NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335,K18331 - 1.12.1.3,1.6.5.3 1.088e-294 925.0
TH2_k127_235052_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 446.0
TH2_k127_235052_2 FMN-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 389.0
TH2_k127_235052_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 375.0
TH2_k127_235052_4 - K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006112 256.0
TH2_k127_235052_5 PQQ-like domain - - - 0.00000001973 63.0
TH2_k127_237420_0 DNA-templated transcription, initiation K03088 - - 0.000000000000000002399 94.0
TH2_k127_237420_1 FecR protein - - - 0.0001558 53.0
TH2_k127_2384864_0 Belongs to the xylose isomerase family K01805 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 443.0
TH2_k127_2384864_1 TonB dependent receptor K02014,K16087,K16089,K16092 - - 0.0000000000000000000000000000000000000000000000006202 198.0
TH2_k127_2391078_0 A-macroglobulin complement component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 419.0
TH2_k127_2391078_1 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 358.0
TH2_k127_2391078_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 299.0
TH2_k127_2391078_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000008649 195.0
TH2_k127_2391078_4 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.0000000000000000000000000000000000000002364 158.0
TH2_k127_2391078_5 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000001925 133.0
TH2_k127_2393845_0 pyruvate K00627,K01571,K01960,K02160,K03416,K20140 - 2.1.3.1,2.3.1.12,4.1.1.3,6.4.1.1,6.4.1.7 1.299e-225 717.0
TH2_k127_2393845_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 434.0
TH2_k127_2393845_10 - - - - 0.0000000000000000000000000000000000000000000004101 173.0
TH2_k127_2393845_11 Cellobiose phosphorylase - - - 0.00000000000000000000000000000000000000006685 160.0
TH2_k127_2393845_12 MraZ protein, putative antitoxin-like K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000003508 74.0
TH2_k127_2393845_13 COG1388 FOG LysM repeat K19223,K19224 - - 0.00000000001736 78.0
TH2_k127_2393845_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 367.0
TH2_k127_2393845_3 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 374.0
TH2_k127_2393845_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 337.0
TH2_k127_2393845_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 319.0
TH2_k127_2393845_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005231 285.0
TH2_k127_2393845_7 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001838 274.0
TH2_k127_2393845_8 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000003298 258.0
TH2_k127_2393845_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000007334 253.0
TH2_k127_2399233_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 408.0
TH2_k127_2399233_1 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000005247 248.0
TH2_k127_2399233_2 - - - - 0.0000000000000000000000000000000000000000000009376 188.0
TH2_k127_2419685_0 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 296.0
TH2_k127_2419685_1 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007444 236.0
TH2_k127_2419685_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000001376 150.0
TH2_k127_2419685_3 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000000000000000343 119.0
TH2_k127_2419685_4 O-Antigen ligase - - - 0.00001026 57.0
TH2_k127_2419685_5 PFAM glycosyl transferase group 1 - - - 0.00009981 49.0
TH2_k127_2433722_0 Methionine biosynthesis protein MetW - - - 0.00000000001208 74.0
TH2_k127_2433722_1 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000003787 68.0
TH2_k127_2433722_2 Glycosyltransferase like family 2 K20444 - - 0.000001727 54.0
TH2_k127_2433722_3 Protein of unknown function (DUF502) - - - 0.0001485 45.0
TH2_k127_2434570_0 Sulfatase-modifying factor enzyme 1 - - - 9.616e-221 741.0
TH2_k127_2448274_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 450.0
TH2_k127_2448274_1 Pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000004843 93.0
TH2_k127_2448274_2 Putative regulatory protein - - - 0.000000006527 60.0
TH2_k127_2448274_3 Transglutaminase-like superfamily - - - 0.00003828 56.0
TH2_k127_2453765_0 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000003631 223.0
TH2_k127_2453765_1 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000009375 222.0
TH2_k127_2453765_2 - - - - 0.0000000000004525 82.0
TH2_k127_2453765_3 Peptidase_C39 like family - - - 0.000006129 59.0
TH2_k127_2475381_0 phosphopantetheine binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 528.0
TH2_k127_2475381_1 MaoC like domain - - - 0.0000000000000000000000000000000000000000000002305 177.0
TH2_k127_2475381_2 Phosphopantetheine attachment site K02078 - - 0.0000000000001 74.0
TH2_k127_2475381_3 polysaccharide deacetylase - - - 0.0000000000003022 79.0
TH2_k127_2478235_0 Dual specificity phosphatase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001424 260.0
TH2_k127_2478235_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000008844 225.0
TH2_k127_2478235_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000002961 193.0
TH2_k127_2478235_3 HNH nucleases - - - 0.00000000000000000000000000000000001786 140.0
TH2_k127_2478235_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000003581 134.0
TH2_k127_2478235_5 radical SAM domain - - - 0.000000000000000000000000000000858 138.0
TH2_k127_2478235_6 Sel1-like repeats. K07126 - - 0.00000000000000000000000000001172 126.0
TH2_k127_2478235_7 Methylase of polypeptide chain release - - - 0.0004154 50.0
TH2_k127_2487914_0 Collagenase K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000009118 228.0
TH2_k127_2487914_1 HAMP domain K07641,K14980 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000002034 226.0
TH2_k127_2487914_2 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000000000000000000000000005087 192.0
TH2_k127_2487914_3 beta-galactosidase activity K01190,K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000001771 170.0
TH2_k127_2487914_4 TraB family K09973 - - 0.00000000000000000000000000000000000000000009578 184.0
TH2_k127_2487914_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000003426 134.0
TH2_k127_2487914_6 NACHT and Ankyrin domain protein - - - 0.00000000000000000000005741 109.0
TH2_k127_2487914_7 gag-polyprotein putative aspartyl protease - - - 0.00000000000007782 82.0
TH2_k127_2487914_8 Plasmid stability protein K21495 - - 0.0002377 46.0
TH2_k127_2492973_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K19956 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 584.0
TH2_k127_2492973_1 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 314.0
TH2_k127_2492973_2 Isochorismatase family - - - 0.0000000000000000000000000003278 126.0
TH2_k127_2497253_0 Pectate lyase - - - 0.00000007016 66.0
TH2_k127_252463_0 PFAM Transposase, IS4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 432.0
TH2_k127_252463_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 298.0
TH2_k127_252463_2 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.0003912 43.0
TH2_k127_2529504_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 398.0
TH2_k127_2529504_1 PFAM Amidohydrolase 3 - - - 0.00000000000000000000000000000000000000000000000000003266 195.0
TH2_k127_2529504_2 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.0006253 47.0
TH2_k127_2541384_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000001662 134.0
TH2_k127_2541384_1 COG1520 FOG WD40-like repeat - - - 0.0003357 51.0
TH2_k127_2542605_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.755e-231 732.0
TH2_k127_2542605_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000354 75.0
TH2_k127_2545064_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 4.829e-221 701.0
TH2_k127_2545064_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 595.0
TH2_k127_2545064_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 374.0
TH2_k127_2559045_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 558.0
TH2_k127_2559045_1 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000006284 200.0
TH2_k127_2559045_2 PFAM Bacterial type II secretion system protein F domain K02653 - - 0.0000000000000000000000000000000000000521 154.0
TH2_k127_2559045_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000003548 86.0
TH2_k127_2559045_4 antisigma factor binding K04749 - - 0.000001142 56.0
TH2_k127_2566737_0 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 337.0
TH2_k127_2566737_1 Uncharacterized conserved protein (DUF2294) - - - 0.00000000000000000000000000000000000000006018 156.0
TH2_k127_2566737_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.000008339 49.0
TH2_k127_2570461_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000426 263.0
TH2_k127_2570461_1 radical SAM domain protein K22226 - - 0.00000000000000000000000000000000000000000000000001336 196.0
TH2_k127_2570461_2 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000008989 138.0
TH2_k127_2570461_3 ABC transporter - - - 0.0000000000000000000000000000002676 131.0
TH2_k127_2592428_0 - - - - 0.00002556 56.0
TH2_k127_2592428_1 - - - - 0.000355 46.0
TH2_k127_2614286_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 320.0
TH2_k127_2614286_1 Histidine kinase - - - 0.00000000000000000000000000000005353 140.0
TH2_k127_2637624_0 General secretory system II protein E domain protein K02454,K02652 - - 1.105e-201 643.0
TH2_k127_2637624_1 General secretory system II protein E domain protein K02652 - - 1.222e-194 622.0
TH2_k127_2637624_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 497.0
TH2_k127_2637624_3 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009333 467.0
TH2_k127_2637624_4 lipid A export permease ATP-binding protein MsbA K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001558 281.0
TH2_k127_2637624_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000006996 229.0
TH2_k127_2655330_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009071 284.0
TH2_k127_2655330_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000005563 213.0
TH2_k127_266825_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000166 219.0
TH2_k127_2704529_0 - - - - 0.000000000000000000000006007 120.0
TH2_k127_2719102_0 glucuronate isomerase activity K01812 GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 5.3.1.12 4.056e-206 651.0
TH2_k127_2719102_1 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 511.0
TH2_k127_2719102_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001974 291.0
TH2_k127_2719102_3 - - - - 0.0000000000001695 73.0
TH2_k127_2719102_4 Ami_3 K01448 - 3.5.1.28 0.0002139 53.0
TH2_k127_2740144_0 Sodium:neurotransmitter symporter family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 379.0
TH2_k127_2740144_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004505 280.0
TH2_k127_2740144_2 GAF domain K12266 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008841 270.0
TH2_k127_2740144_3 PFAM Helix-turn-helix - - - 0.000000000000000004003 87.0
TH2_k127_2740144_4 toxin-antitoxin pair type II binding K19159 - - 0.00000000000002056 76.0
TH2_k127_2748803_0 Large extracellular alpha-helical protein K06894 - - 0.0 1060.0
TH2_k127_2798489_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1194.0
TH2_k127_2798489_1 beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 528.0
TH2_k127_2798489_2 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000007038 201.0
TH2_k127_280630_0 Radical SAM protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002189 273.0
TH2_k127_280630_1 Tetratricopeptide repeat - - - 0.0000000001272 72.0
TH2_k127_283263_0 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000006205 177.0
TH2_k127_283263_1 protocatechuate 3,4-dioxygenase activity K03088 - - 0.0000000000000000000000000000000528 145.0
TH2_k127_2843550_0 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000002941 141.0
TH2_k127_2843550_1 CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238 - - - 0.0004252 49.0
TH2_k127_2846875_0 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 396.0
TH2_k127_2846875_1 Fimbrial assembly K02662 - - 0.000002102 60.0
TH2_k127_2850415_0 Melibiase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001453 292.0
TH2_k127_2850415_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000004132 88.0
TH2_k127_2855691_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 8.382e-261 818.0
TH2_k127_2855691_1 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000001556 154.0
TH2_k127_2855691_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 0.0000001536 53.0
TH2_k127_2877517_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 478.0
TH2_k127_2877517_1 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 367.0
TH2_k127_2877517_2 PFAM IS66 Orf2 family protein K07484 - - 0.0000000000000000000000000000000000000000000004666 168.0
TH2_k127_2877517_3 - - - - 0.000000008018 62.0
TH2_k127_2923221_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 477.0
TH2_k127_2923221_1 PFAM Xylose isomerase domain-containing protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001309 253.0
TH2_k127_2923221_2 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000001314 144.0
TH2_k127_2923221_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000522 99.0
TH2_k127_2955060_0 MreB/Mbl protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002874 272.0
TH2_k127_2955060_1 nucleotidyltransferase activity K07076 - - 0.0000000003288 66.0
TH2_k127_2955060_2 PFAM HEPN domain - - - 0.000000001123 62.0
TH2_k127_2967196_0 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004424 257.0
TH2_k127_2967196_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000003524 212.0
TH2_k127_2967196_2 Hydrogenase nickel incorporation protein hypA K04651 - - 0.00000000263 61.0
TH2_k127_2967196_3 Short C-terminal domain - - - 0.0006817 46.0
TH2_k127_2968923_0 Site-specific recombinase, DNA invertase Pin - - - 3.068e-224 715.0
TH2_k127_2968923_1 Transposase K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 600.0
TH2_k127_2968923_2 protein kinase activity - - - 0.000000000000000000000000002522 115.0
TH2_k127_2968923_3 PFAM IS66 Orf2 like protein K07484 - - 0.000000000000000000127 93.0
TH2_k127_2968923_5 PFAM IS66 Orf2 like protein K07484 - - 0.000001229 52.0
TH2_k127_2977747_0 Pfam Methyltransferase - - - 0.0000000000000000000000000000000000000000006366 177.0
TH2_k127_2977747_1 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0000000001016 72.0
TH2_k127_3057616_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000007425 119.0
TH2_k127_3057616_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000008787 106.0
TH2_k127_3057616_2 RDD family - - - 0.00000000000004347 81.0
TH2_k127_3057616_4 Uncharacterized protein conserved in bacteria (DUF2057) - - - 0.0001053 53.0
TH2_k127_3114421_0 Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 469.0
TH2_k127_3114421_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000008462 124.0
TH2_k127_3114421_2 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000000001211 96.0
TH2_k127_3114421_3 Oxaloacetate decarboxylase K01571 - 4.1.1.3 0.00000001402 61.0
TH2_k127_3114421_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00001324 50.0
TH2_k127_3118426_0 Molecular chaperone. Has ATPase activity K04079 - - 5.999e-196 626.0
TH2_k127_3118426_1 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000006537 215.0
TH2_k127_3118426_2 chorismate mutase K01850 GO:0000162,GO:0003674,GO:0003824,GO:0004106,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006568,GO:0006570,GO:0006571,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016866,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 5.4.99.5 0.00000000006405 64.0
TH2_k127_3118426_3 PD-(D/E)XK nuclease superfamily - - - 0.000000003048 65.0
TH2_k127_3155105_0 PFAM ABC transporter related K10441,K10545 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 488.0
TH2_k127_3155105_1 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 339.0
TH2_k127_3155105_2 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007872 271.0
TH2_k127_3155105_3 PFAM Short-chain dehydrogenase reductase SDR K00046,K00065 - 1.1.1.127,1.1.1.69 0.000000000000000000000000000000000000000000000000001279 192.0
TH2_k127_3155105_4 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000002344 160.0
TH2_k127_3163137_0 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000009954 158.0
TH2_k127_3163137_2 GIY-YIG catalytic domain - - - 0.0000000002724 65.0
TH2_k127_3180244_0 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001775 266.0
TH2_k127_3180244_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000002831 166.0
TH2_k127_3180244_2 PFAM Transposase IS200 like - - - 0.00000004805 58.0
TH2_k127_3180244_3 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0002032 51.0
TH2_k127_3208989_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000007076 113.0
TH2_k127_3208989_1 Belongs to the peptidase S8 family K13276 GO:0005575,GO:0005576 - 0.00000001451 63.0
TH2_k127_3208989_2 LysM domain - - - 0.0000117 57.0
TH2_k127_3212399_0 Transposase DDE domain - - - 7.477e-214 681.0
TH2_k127_3212399_1 PFAM glycoside hydrolase family 29 (alpha-L-fucosidase) K01206 - 3.2.1.51 1.688e-212 665.0
TH2_k127_3212399_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 539.0
TH2_k127_3212399_3 nitric oxide reductase activity K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006596 406.0
TH2_k127_3278454_0 PFAM Prenyltransferase squalene oxidase - - - 0.0000000000000000000000000000000000000000003439 166.0
TH2_k127_3278454_1 Phospholipase - - - 0.00002226 57.0
TH2_k127_3305425_0 Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.0 1252.0
TH2_k127_3305425_1 Domain of unknown function (DUF1961) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005457 248.0
TH2_k127_3305425_2 PFAM DNA alkylation repair enzyme - - - 0.000000000000000000000000000000248 127.0
TH2_k127_3305425_3 polysaccharide deacetylase - - - 0.0000000000000001329 87.0
TH2_k127_3309621_0 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 433.0
TH2_k127_3309621_1 - - - - 0.00000000000000000000000000000000000000000004157 175.0
TH2_k127_3309621_2 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000006028 114.0
TH2_k127_3309621_3 nuclease K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.00000000006444 65.0
TH2_k127_3309621_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000003618 58.0
TH2_k127_3309621_5 E-Z type HEAT repeats - - - 0.0000001982 60.0
TH2_k127_3322300_0 LexA-binding, inner membrane-associated putative hydrolase - - - 0.000000000000000000000000000000000000000000001624 177.0
TH2_k127_3322300_1 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.00000000000000000000000000000000000000000000385 174.0
TH2_k127_3322300_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000002642 138.0
TH2_k127_3322300_3 YacP-like NYN domain - - - 0.00002565 55.0
TH2_k127_3346084_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 419.0
TH2_k127_3346084_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000001545 185.0
TH2_k127_3346084_3 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.0000000000000000000000009253 113.0
TH2_k127_3346084_4 - - - - 0.00000000000000000004644 96.0
TH2_k127_3353252_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 1.152e-292 922.0
TH2_k127_3353252_1 Domain of unknown function (DUF3943) - - - 0.0000000000000000004591 101.0
TH2_k127_3367687_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 575.0
TH2_k127_3367687_1 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 409.0
TH2_k127_3367687_2 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.000000000000000000000000000000000000000000000000000000000000000000003606 261.0
TH2_k127_3367687_3 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000001433 122.0
TH2_k127_3367687_4 - - - - 0.0000000000000000000000000001561 134.0
TH2_k127_3367687_5 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000001002 96.0
TH2_k127_3367687_6 TIGRFAM transcriptional regulator, AbrB family - - - 0.0000000000000000003501 89.0
TH2_k127_3367687_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000001122 73.0
TH2_k127_3367687_8 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01077 - 3.1.3.1 0.00000000007333 74.0
TH2_k127_3367687_9 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000009337 66.0
TH2_k127_3377667_0 PFAM transposase IS4 family protein - - - 0.000000000000000000000000000000004163 146.0
TH2_k127_3389709_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005338 269.0
TH2_k127_3389709_1 PFAM Xylose isomerase domain-containing protein TIM barrel - - - 0.00000000000000001196 85.0
TH2_k127_3389709_3 lyase activity - - - 0.0006922 52.0
TH2_k127_3393161_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 383.0
TH2_k127_3393161_1 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000044 231.0
TH2_k127_3393161_2 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.000000000000000000000000000000001332 138.0
TH2_k127_3393161_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000006336 113.0
TH2_k127_3412320_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000002533 184.0
TH2_k127_3412320_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000089 174.0
TH2_k127_3412320_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000651 149.0
TH2_k127_3412320_4 chlorophyll binding - - - 0.00000000000000000000000000005273 132.0
TH2_k127_3412320_5 Outer membrane protein beta-barrel domain - - - 0.00000000000299 74.0
TH2_k127_3415998_0 Bacterial type II and III secretion system protein K02666 - - 0.000000000000000000000000000000002411 147.0
TH2_k127_3420356_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000001026 266.0
TH2_k127_3420356_1 Methionine biosynthesis protein MetW - - - 0.000000000000000000000577 106.0
TH2_k127_3420356_2 Glycosyl transferase 4-like domain - - - 0.0000004577 62.0
TH2_k127_3420356_3 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000404 53.0
TH2_k127_3420954_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.31e-255 826.0
TH2_k127_3420954_1 Lipid kinase - - - 0.00000000000000000000000000000000000000005567 175.0
TH2_k127_3420954_2 O-methyltransferase, family 2 - - - 0.00000000000000000000006992 103.0
TH2_k127_3420954_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000009383 98.0
TH2_k127_3420954_4 Regulatory protein, FmdB family - - - 0.00007813 49.0
TH2_k127_3420954_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0003013 51.0
TH2_k127_3424565_0 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 297.0
TH2_k127_3424565_1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001745 257.0
TH2_k127_3424565_2 Right handed beta helix region - - - 0.0000000000000000000000000000000000000001086 166.0
TH2_k127_3428960_0 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000000000000001586 223.0
TH2_k127_3428960_1 dCMP deaminase activity K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000006113 201.0
TH2_k127_3428960_2 - - - - 0.00000000000000000000000000000000000000000159 173.0
TH2_k127_3428960_3 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000001253 136.0
TH2_k127_3428960_4 - - - - 0.000000000000000000000000000001009 126.0
TH2_k127_3428960_5 Methyltransferase domain - - - 0.000000000000004405 83.0
TH2_k127_3451758_0 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 344.0
TH2_k127_3451758_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0000000000000000000000000000000000000003114 149.0
TH2_k127_3451758_2 - - - - 0.0000000000000000000000000000000000007778 143.0
TH2_k127_3451758_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00002518 55.0
TH2_k127_3451758_4 PFAM Di-haem cytochrome c - - - 0.0008902 49.0
TH2_k127_3457466_0 PFAM Type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 388.0
TH2_k127_3457466_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 300.0
TH2_k127_3457466_2 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000009047 232.0
TH2_k127_3457466_3 phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000003157 164.0
TH2_k127_3457466_4 ABC-2 family transporter protein - - - 0.0000004233 61.0
TH2_k127_34613_0 aspartate-tRNA(Asn) ligase activity K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 581.0
TH2_k127_34613_1 Histidyl-trna synthetase K01892,K14442 GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 3.6.4.13,6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 310.0
TH2_k127_3470260_0 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 317.0
TH2_k127_3470260_1 permease - - - 0.00000791 55.0
TH2_k127_3471764_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 468.0
TH2_k127_3471764_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008208 271.0
TH2_k127_3471764_2 Phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000001598 160.0
TH2_k127_3479009_0 Dehydratase family K01687 - 4.2.1.9 2.658e-235 739.0
TH2_k127_3479009_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 9.698e-195 622.0
TH2_k127_3479009_2 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 376.0
TH2_k127_3479009_3 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002956 291.0
TH2_k127_3479009_4 Belongs to the bacterial histone-like protein family K03530,K04764 - - 0.0000000000000000000000002128 110.0
TH2_k127_3479009_5 Histidyl-trna synthetase K01892,K14442 GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 3.6.4.13,6.1.1.21 0.000000000000000000000002348 108.0
TH2_k127_3479009_6 Glycosyl transferase family 21 - - - 0.0000000000005034 71.0
TH2_k127_3481589_0 Pyruvate formate lyase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 601.0
TH2_k127_3481589_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 302.0
TH2_k127_3481589_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000005684 260.0
TH2_k127_3481589_3 COG1082 Sugar phosphate - - - 0.0000000000000000000000000000000000000000000000000003774 195.0
TH2_k127_3481589_4 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000008574 140.0
TH2_k127_3481589_5 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000004199 61.0
TH2_k127_3481589_6 AraC-like ligand binding domain - - - 0.00000009254 64.0
TH2_k127_3502059_0 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000007705 186.0
TH2_k127_3502059_1 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000007205 162.0
TH2_k127_3502059_2 - - - - 0.00000000000000000000000003375 118.0
TH2_k127_3502059_3 Periplasmic binding proteins and sugar binding domain of the LacI family - - - 0.0003983 51.0
TH2_k127_3509256_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 8.6e-206 659.0
TH2_k127_3509256_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 395.0
TH2_k127_3509256_2 Peptidase C26 K07010 - - 0.00000000000000000000000000000000001115 142.0
TH2_k127_3509256_3 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000004603 124.0
TH2_k127_3509256_4 antisigma factor binding - - - 0.00000000000000000951 96.0
TH2_k127_3509256_5 - - - - 0.000000004262 68.0
TH2_k127_3516419_0 Vault protein inter-alpha-trypsin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 478.0
TH2_k127_3516419_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 310.0
TH2_k127_3516419_2 cellulase activity - - - 0.000005871 52.0
TH2_k127_3517621_0 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000001524 191.0
TH2_k127_3517621_1 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000002837 157.0
TH2_k127_3517621_2 Cytochrome C biogenesis protein - - - 0.000000000000000000002314 105.0
TH2_k127_3517621_3 Protein of unknown function (DUF1573) - - - 0.00000002149 66.0
TH2_k127_3526927_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 497.0
TH2_k127_3526927_1 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 354.0
TH2_k127_3526927_2 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 323.0
TH2_k127_3526927_3 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 306.0
TH2_k127_3526927_4 Oxidoreductase family, C-terminal alpha/beta domain K18652 - 1.1.1.361 0.0000000000000000000000000000000000000000000000000000000000000000000000000000054 284.0
TH2_k127_3526927_5 Pfam Sulfatase - - - 0.00000000000000007997 82.0
TH2_k127_3539850_0 Large extracellular alpha-helical protein K06894 - - 5.668e-290 914.0
TH2_k127_3562553_0 Pfam:DUF1498 - - - 0.0000000000000000000000000000000000000000000000000000000000000003509 224.0
TH2_k127_3562553_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000005293 203.0
TH2_k127_3563985_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 351.0
TH2_k127_3563985_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001941 272.0
TH2_k127_3572137_0 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000000000000000000000000000006589 223.0
TH2_k127_3572137_1 Calcineurin-like phosphoesterase - - - 0.000000001565 70.0
TH2_k127_3597494_0 PBS lyase HEAT-like repeat - - - 0.00000000000003591 87.0
TH2_k127_3597494_1 PQQ-like domain - - - 0.00000000005615 72.0
TH2_k127_3597494_2 Pectate lyase superfamily protein - - - 0.000287 53.0
TH2_k127_3597494_3 COG1413 FOG HEAT repeat K22221 - - 0.0004183 54.0
TH2_k127_3615464_0 Beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 398.0
TH2_k127_3615464_1 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000002836 219.0
TH2_k127_3615464_2 regulation of translation K03530 - - 0.00000000000000000000002229 103.0
TH2_k127_3617634_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 316.0
TH2_k127_3617634_1 Rhodanese Homology Domain K03972 - - 0.00000000000000000000006114 102.0
TH2_k127_3627961_0 Formate--tetrahydrofolate ligase K00288,K01938 GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.5,3.5.4.9,6.3.4.3 5.183e-280 870.0
TH2_k127_3627961_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000003683 181.0
TH2_k127_3631118_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.0 1184.0
TH2_k127_3631118_1 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 311.0
TH2_k127_3631118_2 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004871 276.0
TH2_k127_3631118_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000004135 254.0
TH2_k127_3631118_4 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000004156 250.0
TH2_k127_3631118_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000001224 162.0
TH2_k127_3631118_6 Phosphate-selective porin O and P - - - 0.00000000000000000000000007865 120.0
TH2_k127_3631118_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000003113 83.0
TH2_k127_3634037_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1182.0
TH2_k127_3634037_1 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 312.0
TH2_k127_3634037_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000000000000000005718 211.0
TH2_k127_3640870_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 514.0
TH2_k127_3640870_1 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000009337 175.0
TH2_k127_3640870_2 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000002591 179.0
TH2_k127_3640870_3 Protein conserved in bacteria - - - 0.0000000000007357 85.0
TH2_k127_3643779_0 ammonia-lyase activity K01745,K10774,K10775,K21181 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009698,GO:0009699,GO:0009800,GO:0009803,GO:0009987,GO:0016043,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016866,GO:0016869,GO:0019438,GO:0019748,GO:0019752,GO:0022607,GO:0032787,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044550,GO:0045548,GO:0046394,GO:0050368,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 4.3.1.23,4.3.1.24,4.3.1.3,5.4.3.6 1.224e-239 758.0
TH2_k127_3643779_1 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000008182 239.0
TH2_k127_3643779_2 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000001884 160.0
TH2_k127_3643779_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000007469 149.0
TH2_k127_3643779_4 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000001873 108.0
TH2_k127_3656794_0 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 486.0
TH2_k127_3656794_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000001627 120.0
TH2_k127_3656794_2 - - - - 0.00003538 47.0
TH2_k127_3659913_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 377.0
TH2_k127_3659913_1 Na Pi-cotransporter K03324 - - 0.00000000000000000000000000000000000000000000000000000000003716 226.0
TH2_k127_3659913_2 50S ribosomal protein L31 K02909 - - 0.00000000000000000000001926 100.0
TH2_k127_3659913_3 protein methyltransferase activity K02687 - - 0.0000000000004906 74.0
TH2_k127_366840_0 Ammonium Transporter Family K03320 - - 1.293e-222 703.0
TH2_k127_366840_1 Sodium/hydrogen exchanger family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 434.0
TH2_k127_366840_2 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 293.0
TH2_k127_366840_3 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000001777 190.0
TH2_k127_366840_4 Sulfatase - - - 0.0000000000001035 80.0
TH2_k127_366840_5 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0000000001397 64.0
TH2_k127_366840_6 EF-hand domain pair - - - 0.0005579 50.0
TH2_k127_3733518_0 Cys/Met metabolism PLP-dependent enzyme K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 400.0
TH2_k127_3733518_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 296.0
TH2_k127_3772784_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 307.0
TH2_k127_3772784_1 PHP domain protein - - - 0.00000000000000000000000000001738 129.0
TH2_k127_3772784_2 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.000000000000002805 82.0
TH2_k127_3773981_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 409.0
TH2_k127_3773981_1 Trehalase - - - 0.000000000000000000000000000000000000000000000000007033 188.0
TH2_k127_3796869_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009747 284.0
TH2_k127_3796869_1 Predicted permease K07089 - - 0.00000000000000000000000000001498 120.0
TH2_k127_3796869_2 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.00000000000000000000000000004515 132.0
TH2_k127_3834274_0 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000000000000000000002318 201.0
TH2_k127_3834274_1 Biopolymer transport protein K03559 - - 0.00000005502 60.0
TH2_k127_3867959_0 PFAM cobalamin B12-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 608.0
TH2_k127_3867959_1 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000001161 248.0
TH2_k127_3872189_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000001759 73.0
TH2_k127_3872189_1 Domain of unknown function (DUF4091) - - - 0.000000001338 72.0
TH2_k127_3872189_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00003546 58.0
TH2_k127_3907648_0 family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 596.0
TH2_k127_3907648_1 D-galactarate dehydratase altronate hydrolase K16850 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 468.0
TH2_k127_3907648_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 336.0
TH2_k127_3907648_3 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000005647 252.0
TH2_k127_3907648_4 SAF K16849 - 4.2.1.7 0.0000000000000001278 83.0
TH2_k127_3907648_5 AraC-type DNA-binding domain-containing proteins K07506 - - 0.0000000000000003909 88.0
TH2_k127_3907648_6 NAD dependent epimerase dehydratase family protein K16045,K22320 GO:0000166,GO:0003674,GO:0003824,GO:0003854,GO:0004769,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016020,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016853,GO:0016860,GO:0016863,GO:0030283,GO:0033764,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901363 1.1.1.145,1.1.1.412,5.3.3.1 0.000000001469 70.0
TH2_k127_3907709_0 elongation factor G K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 562.0
TH2_k127_3907709_1 Transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001929 249.0
TH2_k127_3907709_2 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000001304 250.0
TH2_k127_3907709_3 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000001842 203.0
TH2_k127_3907709_4 COGs COG1253 Hemolysins and related protein containing CBS domains - - - 0.00000000000000000000000000000000000000000000000000004762 199.0
TH2_k127_3907709_5 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000001744 186.0
TH2_k127_3907709_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000006676 132.0
TH2_k127_3907709_7 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000009091 61.0
TH2_k127_3911469_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 334.0
TH2_k127_3911469_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000005093 209.0
TH2_k127_3911469_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000008735 145.0
TH2_k127_3911469_3 - - - - 0.00000000000000008819 89.0
TH2_k127_3911469_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000001136 53.0
TH2_k127_3911469_5 AraC family - - - 0.0003457 48.0
TH2_k127_3924384_0 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 450.0
TH2_k127_3924384_1 Bacterial type II/III secretion system short domain K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000493 242.0
TH2_k127_3924384_2 PFAM glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000002017 163.0
TH2_k127_3924384_3 general secretion pathway protein K02455 - - 0.000000000000000000000000000000000004622 158.0
TH2_k127_3941432_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.867e-217 695.0
TH2_k127_3941432_1 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 307.0
TH2_k127_3942697_0 - - - - 4.643e-206 653.0
TH2_k127_3942697_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000003433 100.0
TH2_k127_3942697_2 Beta-lactamase - - - 0.000002895 52.0
TH2_k127_3943712_0 tagaturonate epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 511.0
TH2_k127_3943712_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000448 148.0
TH2_k127_3943712_2 Melibiase K07407 - 3.2.1.22 0.000000000000007388 81.0
TH2_k127_3979767_0 DNA topoisomerase K02622 - - 1.753e-237 748.0
TH2_k127_3979767_1 Belongs to the type II topoisomerase GyrA ParC subunit family K02621 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 574.0
TH2_k127_3979767_2 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 343.0
TH2_k127_3983509_0 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003542 261.0
TH2_k127_3983509_1 hydrolase of alkaline phosphatase superfamily K07014 - - 0.0000000000000000000002448 106.0
TH2_k127_3992074_0 - - - - 0.00000000000000000000000000005654 136.0
TH2_k127_3992074_1 - - - - 0.0002045 45.0
TH2_k127_4046795_0 PFAM type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 319.0
TH2_k127_4046795_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 320.0
TH2_k127_4046795_2 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000001822 182.0
TH2_k127_4072925_0 BadF BadG BcrA BcrD - - - 7.393e-276 881.0
TH2_k127_4075118_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004939 282.0
TH2_k127_4075118_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007442 276.0
TH2_k127_4075118_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000008865 235.0
TH2_k127_4115507_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 413.0
TH2_k127_4115507_1 nUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000000000000000000000000000000000000000006653 196.0
TH2_k127_4115507_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000002211 114.0
TH2_k127_4115507_3 - - - - 0.000000000000000006309 88.0
TH2_k127_4115507_4 - - - - 0.0000000000000000159 92.0
TH2_k127_4117184_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 5.177e-222 696.0
TH2_k127_4117184_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.00000000000000000007224 93.0
TH2_k127_4117184_2 Ribonuclease R winged-helix domain K09720 - - 0.000001581 57.0
TH2_k127_4156255_0 transposition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 398.0
TH2_k127_4156255_1 nucleoside hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 339.0
TH2_k127_4195024_0 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 440.0
TH2_k127_4195024_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 324.0
TH2_k127_4195024_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 295.0
TH2_k127_4195024_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000002111 246.0
TH2_k127_4195024_4 Acetyltransferase (GNAT) domain K03830 - - 0.000000000000000000000000000000003291 134.0
TH2_k127_4195024_5 regulation of translation K03530 - - 0.00000000000000000000007767 100.0
TH2_k127_4195024_6 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.00001303 55.0
TH2_k127_4195024_7 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.0000179 53.0
TH2_k127_420350_0 beta-galactosidase K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 558.0
TH2_k127_4253249_0 Psort location Cytoplasmic, score K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 497.0
TH2_k127_4253249_1 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008958 284.0
TH2_k127_4253249_2 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000000000000000001478 121.0
TH2_k127_4263101_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 7.213e-274 853.0
TH2_k127_4263101_1 PFAM Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 389.0
TH2_k127_4263101_2 2 iron, 2 sulfur cluster binding K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000003606 235.0
TH2_k127_4263101_3 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000002232 168.0
TH2_k127_4263101_4 molybdenum cofactor guanylyltransferase activity K03637,K03752,K13818 - 2.7.7.77,4.6.1.17 0.00000000000000000000000000000000000002191 155.0
TH2_k127_4263101_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000001082 149.0
TH2_k127_4263101_6 CAAX protease self-immunity K07052 - - 0.000000000000000000000000004814 122.0
TH2_k127_4263101_7 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000002819 74.0
TH2_k127_4277571_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 473.0
TH2_k127_4277571_1 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 342.0
TH2_k127_4277571_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000001359 262.0
TH2_k127_4277571_3 domain protein - - - 0.00000000000000000000000000000000000000000000001594 178.0
TH2_k127_4277571_4 Nucleotidyltransferase domain - - - 0.0000006713 56.0
TH2_k127_4288608_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 362.0
TH2_k127_4288608_1 Belongs to the helicase family. UvrD subfamily K07465 - - 0.0000000000000000004516 91.0
TH2_k127_4288608_2 Domain of unknown function (DUF1287) K09974 - - 0.0008485 51.0
TH2_k127_4375181_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 296.0
TH2_k127_4375181_1 Alpha galactosidase A K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000082 277.0
TH2_k127_4375181_2 Homeodomain-like domain - - - 0.000000000000000000000000000008002 126.0
TH2_k127_43867_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.000000000000000000000000000001436 139.0
TH2_k127_43867_1 SGNH hydrolase-like domain, acetyltransferase AlgX K19295 - - 0.0004474 52.0
TH2_k127_4410456_0 Sugar ABC transporter permease K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 291.0
TH2_k127_4410456_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001565 266.0
TH2_k127_4410456_2 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000002143 155.0
TH2_k127_4410456_3 transposase activity - - - 0.00000000000000000002323 97.0
TH2_k127_441478_0 sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000003404 167.0
TH2_k127_441478_1 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806,K02821,K03491 - 2.7.1.194,2.7.1.202 0.0000005302 63.0
TH2_k127_4450083_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 305.0
TH2_k127_4450083_1 DDE_Tnp_1-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000001283 248.0
TH2_k127_4450083_2 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000004507 179.0
TH2_k127_4450083_3 Transposase DDE domain - - - 0.0000004322 59.0
TH2_k127_4464053_0 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 392.0
TH2_k127_4464053_1 Alkaline phosphatase K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 365.0
TH2_k127_4464053_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000007538 221.0
TH2_k127_4464053_3 COG0084 Mg-dependent DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000001907 154.0
TH2_k127_4464053_4 Histidine kinase K02484,K07645 - 2.7.13.3 0.000000000000000000000000004487 129.0
TH2_k127_4464053_5 Belongs to the UPF0235 family K09131 - - 0.00000000000001465 78.0
TH2_k127_4464053_6 - - - - 0.000000003347 62.0
TH2_k127_4464053_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0001936 52.0
TH2_k127_4479304_0 hydrolase, family 3 K05349 - 3.2.1.21 4.424e-275 865.0
TH2_k127_4479304_1 nuclease activity - - - 0.000000000000000000000000000000000005576 144.0
TH2_k127_4479304_2 toxin-antitoxin pair type II binding - - - 0.0000000000000000000002483 98.0
TH2_k127_4479304_3 metallopeptidase activity K01179,K08738 - 3.2.1.4 0.000000000000000000004872 96.0
TH2_k127_4479304_4 membrane-bound metal-dependent K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000009461 61.0
TH2_k127_4479304_5 - - - - 0.000003327 61.0
TH2_k127_44849_0 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003216 263.0
TH2_k127_44849_1 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000009348 162.0
TH2_k127_449455_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 323.0
TH2_k127_449455_1 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000001015 166.0
TH2_k127_449455_2 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000004884 153.0
TH2_k127_449455_3 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000003526 126.0
TH2_k127_4504073_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009059 279.0
TH2_k127_4504429_0 Secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 445.0
TH2_k127_4504429_1 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000001935 246.0
TH2_k127_4504429_2 general secretion pathway protein K02456 - - 0.000000000000000000005233 98.0
TH2_k127_4504429_3 Type II secretion system (T2SS), protein J K02459 - - 0.00008228 53.0
TH2_k127_4505314_0 Protein involved in glutamate-1-semialdehyde 2,1-aminomutase activity K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 411.0
TH2_k127_4505314_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 358.0
TH2_k127_4505314_2 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000001029 153.0
TH2_k127_4505314_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000003912 126.0
TH2_k127_4505314_4 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.000000000000000000002722 95.0
TH2_k127_4505314_5 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000443 83.0
TH2_k127_4505314_6 Anti-sigma-K factor rskA - - - 0.0001564 51.0
TH2_k127_4521182_0 Inner membrane component of T3SS, cytoplasmic domain K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 502.0
TH2_k127_4521182_1 flp pilus assembly protein K12510 - - 0.0000000000000000000000000000000000000000000297 171.0
TH2_k127_4521182_2 Flp pilus assembly protein K12511 - - 0.000000000000000000000000000000000000243 162.0
TH2_k127_4521182_3 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000002083 142.0
TH2_k127_4521182_4 Forkhead associated domain - - - 0.0000000001571 72.0
TH2_k127_4537582_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000007433 177.0
TH2_k127_4537582_1 Methionine biosynthesis protein MetW K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000002788 172.0
TH2_k127_4555041_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.302e-232 732.0
TH2_k127_4555041_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 353.0
TH2_k127_4555041_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000004068 177.0
TH2_k127_4555041_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000002806 117.0
TH2_k127_4555041_4 cobalamin catabolic process K13912,K19525 - - 0.0000000000005757 82.0
TH2_k127_4555041_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000003243 59.0
TH2_k127_4569737_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007423 263.0
TH2_k127_4569737_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000475 246.0
TH2_k127_4569737_2 - - - - 0.000000000000000000000000000000000001415 150.0
TH2_k127_4569737_3 COG0845 Membrane-fusion protein - - - 0.000000000000000000000000004335 127.0
TH2_k127_4569737_4 efflux transmembrane transporter activity - - - 0.0000000000000000000001774 113.0
TH2_k127_4569737_5 plasmid stabilization K19092 - - 0.0000000000000001869 81.0
TH2_k127_4569737_6 - - - - 0.000006479 57.0
TH2_k127_4583414_0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.00000000000000000000000002324 115.0
TH2_k127_4583414_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000002341 78.0
TH2_k127_4606409_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 301.0
TH2_k127_4606409_1 PFAM Transposase, IS4-like - - - 0.00000000000000000000000000000000000000000000005182 177.0
TH2_k127_4606409_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000001523 103.0
TH2_k127_4611626_0 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000003639 90.0
TH2_k127_4612262_0 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008042 248.0
TH2_k127_4612262_1 Single Cache domain 2 K02480 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000003325 206.0
TH2_k127_4612262_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000006458 157.0
TH2_k127_4612262_3 DeoR C terminal sensor domain K02444 - - 0.0000000000000000000000000000000000003555 151.0
TH2_k127_4612262_4 regulator - - - 0.000000000000000001305 94.0
TH2_k127_4613126_0 - - - - 0.0000000000000000000000003057 123.0
TH2_k127_4615084_0 negative regulation of protein lipidation K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 402.0
TH2_k127_4615084_1 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000003182 80.0
TH2_k127_4615084_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000001024 74.0
TH2_k127_4634257_0 DNA polymerase type-B family K02336 - 2.7.7.7 2.514e-222 714.0
TH2_k127_4634257_1 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000004617 130.0
TH2_k127_4634257_2 PFAM NAD-dependent epimerase dehydratase K01784,K08678 - 4.1.1.35,5.1.3.2 0.00000000000005977 74.0
TH2_k127_466197_0 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008006 267.0
TH2_k127_466197_1 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.00000000000000000000000000000002954 128.0
TH2_k127_466197_2 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00000000000000000000001926 112.0
TH2_k127_4662436_0 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 303.0
TH2_k127_4662436_1 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000008487 224.0
TH2_k127_4662436_2 PQQ-like domain - - - 0.0000000000000000000000000000000037 146.0
TH2_k127_4665315_0 General secretory system II protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 379.0
TH2_k127_4665315_1 PFAM type II and III secretion system protein K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 320.0
TH2_k127_4665315_2 Pilus assembly protein - - - 0.00000000000000000000000000000000000000000001462 182.0
TH2_k127_4665315_3 - - - - 0.0000000462 64.0
TH2_k127_4675447_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001873 291.0
TH2_k127_4675447_1 - - - - 0.000000000000000000000000000003084 139.0
TH2_k127_4680603_0 PFAM Acetyl-CoA hydrolase transferase - - - 2.02e-216 681.0
TH2_k127_4680603_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000006437 233.0
TH2_k127_4680603_2 Maf-like protein K06287 - - 0.000000000000000000000000000000006647 134.0
TH2_k127_4688693_0 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 335.0
TH2_k127_4688693_1 Ribosomal small subunit Rsm22 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 303.0
TH2_k127_4688693_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000776 211.0
TH2_k127_4688693_3 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000001445 115.0
TH2_k127_4688693_4 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000002275 99.0
TH2_k127_4704612_0 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 534.0
TH2_k127_4704612_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 356.0
TH2_k127_4704612_2 - - - - 0.00000000000002224 84.0
TH2_k127_4704612_3 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.000000000002725 77.0
TH2_k127_4704612_4 SMART helix-turn-helix domain protein K15539 - - 0.000003446 58.0
TH2_k127_4705539_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 471.0
TH2_k127_4705539_1 Glycosyl hydrolases family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 450.0
TH2_k127_4705539_2 PFAM short-chain dehydrogenase reductase SDR K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 323.0
TH2_k127_4705539_3 Outer membrane lipoprotein K05807 - - 0.000000000000009911 85.0
TH2_k127_4715614_0 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000000000000004011 118.0
TH2_k127_4715614_1 - - - - 0.000000000000000000000094 104.0
TH2_k127_4715629_0 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001557 280.0
TH2_k127_4715629_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000001948 222.0
TH2_k127_4715629_2 NUDIX domain K03575 - - 0.000000000000000000000000000000000000000000000000004222 190.0
TH2_k127_4728269_0 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000002627 235.0
TH2_k127_4728269_1 Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000006581 100.0
TH2_k127_4728269_2 Belongs to the ompA family K03640 - - 0.00000000003278 70.0
TH2_k127_4728269_3 MotA TolQ ExbB proton channel K03562 - - 0.0000395 46.0
TH2_k127_4728269_4 TIGRFAM TonB family protein K03646,K03832 - - 0.00008937 54.0
TH2_k127_4731844_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.176e-233 749.0
TH2_k127_4731844_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000663 203.0
TH2_k127_4731844_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000006602 187.0
TH2_k127_4731844_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000002847 171.0
TH2_k127_4731844_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000003723 91.0
TH2_k127_4732002_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 419.0
TH2_k127_4732002_1 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 384.0
TH2_k127_4732002_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000002645 216.0
TH2_k127_4743462_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 481.0
TH2_k127_4743462_1 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005916 282.0
TH2_k127_4743462_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000002628 214.0
TH2_k127_4743462_3 Psort location Cytoplasmic, score K06871 - - 0.0000000000000001443 82.0
TH2_k127_4746407_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 298.0
TH2_k127_4746407_1 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000003241 160.0
TH2_k127_476362_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003186 293.0
TH2_k127_476362_1 O-Antigen ligase K02847 - - 0.00000000000000000000000000000000000000005232 173.0
TH2_k127_476362_2 PFAM Polysaccharide biosynthesis protein - - - 0.0000000000000000000001349 113.0
TH2_k127_476362_3 polysaccharide export K01991 - - 0.0000000000009422 74.0
TH2_k127_4766332_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.676e-286 892.0
TH2_k127_4766332_1 GMP synthase C terminal domain K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 530.0
TH2_k127_4802041_0 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 462.0
TH2_k127_4802041_1 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 426.0
TH2_k127_481563_0 transcriptional K03436 - - 0.0000000000000000000000000000000000000000000000000000000000000006627 230.0
TH2_k127_481563_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000003855 104.0
TH2_k127_481563_2 Forms a complex with YaeT, YfiO, and NlpB K17713 - - 0.0006089 53.0
TH2_k127_4850530_0 Belongs to the glycosyl hydrolase 43 family - - - 0.00000000000000000002078 103.0
TH2_k127_4850530_1 Right handed beta helix region - - - 0.0000000000000000001088 102.0
TH2_k127_4853186_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 365.0
TH2_k127_4853186_1 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 359.0
TH2_k127_4873790_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006059 264.0
TH2_k127_4873790_1 PFAM Glycoside hydrolase, clan GH-D - - - 0.000000000000000428 80.0
TH2_k127_4901970_0 Dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 535.0
TH2_k127_4901970_1 Melibiase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 543.0
TH2_k127_4901970_2 type II secretion K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 464.0
TH2_k127_4901970_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000012 316.0
TH2_k127_4901970_4 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001311 282.0
TH2_k127_4901970_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000001297 191.0
TH2_k127_4901970_6 haloacid dehalogenase-like hydrolase - - - 0.000000000000000003032 98.0
TH2_k127_4901970_7 - - - - 0.0000000000000003506 83.0
TH2_k127_4901970_8 Tetratricopeptide repeat - - - 0.00000000000001142 88.0
TH2_k127_4903636_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001594 282.0
TH2_k127_4903636_1 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006635 257.0
TH2_k127_4912953_0 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 462.0
TH2_k127_4912953_1 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 312.0
TH2_k127_4915984_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 487.0
TH2_k127_4915984_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 378.0
TH2_k127_4915984_2 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 323.0
TH2_k127_4915984_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000239 252.0
TH2_k127_4915984_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000001972 117.0
TH2_k127_4915984_5 transposase activity - - - 0.0000000000000006731 84.0
TH2_k127_4955609_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 336.0
TH2_k127_4955609_1 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000007328 246.0
TH2_k127_4955609_2 ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000006841 232.0
TH2_k127_4959376_0 PFAM SNF2-related protein K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 510.0
TH2_k127_4959376_1 mevalonate kinase activity K00869,K00938,K16190 - 2.7.1.36,2.7.1.43,2.7.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 349.0
TH2_k127_4959376_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 353.0
TH2_k127_4989936_0 to GP 6723233 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 322.0
TH2_k127_4989936_1 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.000000000000001048 83.0
TH2_k127_5008905_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000002552 226.0
TH2_k127_5008905_1 Belongs to the glycosyl hydrolase 2 family - - - 0.0000000000000000000000000000000000007216 154.0
TH2_k127_5017886_0 lipoprotein biosynthetic process K13292 - - 0.00000000000000000000000000000000000000000000000000000000000002249 232.0
TH2_k127_5017886_1 - - - - 0.00001523 56.0
TH2_k127_5017886_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0002646 50.0
TH2_k127_5033447_0 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 334.0
TH2_k127_5033447_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000388 199.0
TH2_k127_5033447_2 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000007377 165.0
TH2_k127_5033447_3 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000000001547 155.0
TH2_k127_5033447_4 - - - - 0.00001888 50.0
TH2_k127_5042556_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1542.0
TH2_k127_5042556_1 Glutamine amidotransferase domain K00764 - 2.4.2.14 6.543e-207 653.0
TH2_k127_5051435_0 peptidyl-tyrosine sulfation - - - 0.000000000857 72.0
TH2_k127_5056667_0 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 523.0
TH2_k127_5056667_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K01406 - 3.4.24.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005597 311.0
TH2_k127_5056667_2 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001392 227.0
TH2_k127_5076357_0 Domain of unknown function (DUF4070) - - - 4.552e-218 688.0
TH2_k127_5076357_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 327.0
TH2_k127_5076357_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 329.0
TH2_k127_5076357_3 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008426 262.0
TH2_k127_5104766_0 BadF BadG BcrA BcrD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 368.0
TH2_k127_5104766_1 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000006212 216.0
TH2_k127_5104766_2 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000001407 177.0
TH2_k127_5104766_3 FAD binding domain K09835 - 5.2.1.13 0.0000000000000000000000203 113.0
TH2_k127_5110740_0 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004151 280.0
TH2_k127_5110740_1 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000001418 226.0
TH2_k127_5110740_2 Toprim-like - - - 0.000000000000000000000000000000000004539 155.0
TH2_k127_5116861_1 Glycosyltransferase Family 4 - - - 0.00000000000000001698 91.0
TH2_k127_5139745_0 Caspase domain - - - 0.000000000000000000000000000000000000000000001958 181.0
TH2_k127_5139745_1 Protein of unknown function (DUF2905) - - - 0.0000000000008603 70.0
TH2_k127_5216809_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 488.0
TH2_k127_5216809_1 rRNA binding K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 371.0
TH2_k127_5216809_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000004061 149.0
TH2_k127_5216809_11 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000001804 155.0
TH2_k127_5216809_12 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000009163 142.0
TH2_k127_5216809_13 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000007532 120.0
TH2_k127_5216809_14 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000001097 109.0
TH2_k127_5216809_15 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000004964 102.0
TH2_k127_5216809_16 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001557 94.0
TH2_k127_5216809_17 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000004139 98.0
TH2_k127_5216809_18 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000009664 91.0
TH2_k127_5216809_19 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000007264 52.0
TH2_k127_5216809_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003661 271.0
TH2_k127_5216809_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000001279 223.0
TH2_k127_5216809_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000352 208.0
TH2_k127_5216809_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000004398 190.0
TH2_k127_5216809_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000006801 189.0
TH2_k127_5216809_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000003546 186.0
TH2_k127_5216809_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000008827 169.0
TH2_k127_5216809_9 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000008564 164.0
TH2_k127_5250858_0 Mut7-C ubiquitin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 318.0
TH2_k127_5250858_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000004456 239.0
TH2_k127_5250858_2 - - - - 0.0000000000000000000000000000000000000000841 154.0
TH2_k127_5250858_3 PFAM PilT protein domain protein - - - 0.00000000000000000005391 94.0
TH2_k127_5250858_4 WbqC-like protein family - - - 0.0000000000000000001012 90.0
TH2_k127_5250858_5 PcfJ-like protein - - - 0.00000000009286 74.0
TH2_k127_5250858_6 Belongs to the peptidase S26 family - - - 0.000003096 59.0
TH2_k127_5250858_7 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0007487 45.0
TH2_k127_5257290_0 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 407.0
TH2_k127_5257290_1 PFAM ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 370.0
TH2_k127_5257290_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 374.0
TH2_k127_5259153_0 Protein of unknown function (DUF1189) - - - 0.000000000000000000000003722 110.0
TH2_k127_52944_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 345.0
TH2_k127_52944_1 RNA polymerase sigma factor, sigma-70 family - - - 0.0000000000000000000000000000000000002451 161.0
TH2_k127_53191_0 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 469.0
TH2_k127_53191_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002314 292.0
TH2_k127_53191_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000208 287.0
TH2_k127_53191_3 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004627 269.0
TH2_k127_53191_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000001936 158.0
TH2_k127_53191_5 - - - - 0.00000000000000000000000000000000000001313 158.0
TH2_k127_5345688_0 Cation transport protein K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 334.0
TH2_k127_5345688_1 Potassium uptake system protein K03499 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000005576 188.0
TH2_k127_5345688_2 - - - - 0.000000000007981 68.0
TH2_k127_5345688_3 histidine kinase HAMP region domain protein - - - 0.00001965 55.0
TH2_k127_5345688_4 beta-galactosidase K12308 - 3.2.1.23 0.0001036 55.0
TH2_k127_53642_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 1.495e-260 818.0
TH2_k127_53642_1 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 520.0
TH2_k127_53642_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K17999 - 1.12.1.4,1.6.5.3 0.0000000000000000000000000000000000000000001354 170.0
TH2_k127_53642_3 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000001954 109.0
TH2_k127_5388012_0 peptidyl-tyrosine sulfation - - - 0.000000000663 72.0
TH2_k127_5388012_1 COG1520 FOG WD40-like repeat - - - 0.00007435 56.0
TH2_k127_5422378_0 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 523.0
TH2_k127_5422378_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 441.0
TH2_k127_5422378_2 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 407.0
TH2_k127_5422378_3 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 301.0
TH2_k127_5422378_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000001303 231.0
TH2_k127_542433_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 469.0
TH2_k127_542433_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 337.0
TH2_k127_542433_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 341.0
TH2_k127_542433_3 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003603 278.0
TH2_k127_542433_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000372 258.0
TH2_k127_542433_5 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000008934 239.0
TH2_k127_542433_6 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000002071 113.0
TH2_k127_5454726_1 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.00000000000000000000000000002775 123.0
TH2_k127_5454726_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000009978 101.0
TH2_k127_5512163_0 Putative methyltransferase - - - 0.00000000000000000000000000000647 130.0
TH2_k127_551866_0 DNA modification - - - 5.88e-273 862.0
TH2_k127_551866_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 519.0
TH2_k127_551866_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000001438 197.0
TH2_k127_551866_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00002085 49.0
TH2_k127_5542120_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.552e-268 849.0
TH2_k127_5542120_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 605.0
TH2_k127_5542120_2 tRNA synthetases class II (D, K and N) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 302.0
TH2_k127_5542120_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000006657 216.0
TH2_k127_5573162_0 PFAM ABC transporter related K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 597.0
TH2_k127_5573162_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000005916 166.0
TH2_k127_5573162_2 Rubrerythrin - - - 0.0001911 49.0
TH2_k127_5585219_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 571.0
TH2_k127_5585219_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 321.0
TH2_k127_5585219_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 292.0
TH2_k127_5585219_3 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000007586 266.0
TH2_k127_5585219_4 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000008256 246.0
TH2_k127_5585219_5 Haloacid Dehalogenase Superfamily Class (subfamily) IIA K01101,K02566 - 3.1.3.41 0.00000000000000000000000000000000000000000000000000000000000000000008796 255.0
TH2_k127_5595515_0 lipid A export permease ATP-binding protein MsbA K11085 - - 0.00000000000000000000000000000000000000000000002433 190.0
TH2_k127_5595515_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000007642 61.0
TH2_k127_5595515_2 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000001455 56.0
TH2_k127_5598647_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 397.0
TH2_k127_5598647_1 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 291.0
TH2_k127_5598647_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000006149 164.0
TH2_k127_5613092_0 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000001347 128.0
TH2_k127_5613092_1 Ribbon-helix-helix protein, copG family - - - 0.0008077 46.0
TH2_k127_5615375_0 peptidyl-tyrosine sulfation - - - 0.00000002251 67.0
TH2_k127_5628873_0 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 373.0
TH2_k127_5628873_1 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 288.0
TH2_k127_5628873_2 ATPases associated with a variety of cellular activities K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000462 264.0
TH2_k127_5628873_3 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002731 269.0
TH2_k127_5628873_4 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000002239 246.0
TH2_k127_5628873_5 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000000000000000000000000000000000000000008078 228.0
TH2_k127_5628873_6 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000002071 217.0
TH2_k127_5628873_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000001416 111.0
TH2_k127_564165_0 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 399.0
TH2_k127_564165_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000005083 98.0
TH2_k127_564165_2 CsbD-like - - - 0.0000000000000297 80.0
TH2_k127_564165_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000009155 68.0
TH2_k127_5647686_0 Mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 306.0
TH2_k127_5647686_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000002781 214.0
TH2_k127_5647686_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000007773 152.0
TH2_k127_5647686_3 quinolinate catabolic process K00767,K03813 - 2.4.2.19 0.000000000000000000000000000000000002746 142.0
TH2_k127_5647686_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000002978 136.0
TH2_k127_5666913_0 - - - - 0.0 1802.0
TH2_k127_5666913_1 - K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 481.0
TH2_k127_5666913_2 PFAM Glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.0000000000000000000000000000000000002778 147.0
TH2_k127_5666913_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000001318 79.0
TH2_k127_5674534_0 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 302.0
TH2_k127_5674534_1 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000009121 215.0
TH2_k127_5674534_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000114 176.0
TH2_k127_5674534_3 VWA domain containing CoxE-like protein K07114 - - 0.00000000000000000000000000002451 123.0
TH2_k127_5674534_4 protein-disulfide reductase activity - - - 0.0000000006062 72.0
TH2_k127_5682415_0 FAD binding domain K00278,K03388 - 1.4.3.16,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.228e-195 638.0
TH2_k127_5682415_1 protein kinase activity - - - 0.0000000000000000000000000000000000006749 152.0
TH2_k127_5682415_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000001691 73.0
TH2_k127_5717224_0 PIN domain - - - 0.0000000000000000000000000000000002999 137.0
TH2_k127_5717224_1 Oxidoreductase - - - 0.000000000000000000000002857 115.0
TH2_k127_5717224_2 SpoVT / AbrB like domain - - - 0.000000000000000003016 86.0
TH2_k127_5717224_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00003153 47.0
TH2_k127_5722719_0 synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003185 275.0
TH2_k127_5722719_1 PFAM Methionine synthase, B12-binding module, cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001972 263.0
TH2_k127_5722719_2 Transcriptional regulator, AraC family - - - 0.00000000000000000000001533 113.0
TH2_k127_5735328_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000001804 241.0
TH2_k127_5736931_0 - - - - 0.00000000000000000000000000000003631 131.0
TH2_k127_5736931_1 - - - - 0.00002578 56.0
TH2_k127_5736931_2 Bacterial Ig-like domain - - - 0.0001141 55.0
TH2_k127_5736931_3 Histidine kinase - - - 0.0008329 48.0
TH2_k127_5740441_0 Glycoside hydrolase family 3 K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000003808 231.0
TH2_k127_5754950_0 PFAM oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 484.0
TH2_k127_5754950_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000006794 174.0
TH2_k127_5756228_0 amino acid activation for nonribosomal peptide biosynthetic process K05889,K17713 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 405.0
TH2_k127_5756228_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 333.0
TH2_k127_5756228_2 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 297.0
TH2_k127_5756228_3 - - - - 0.000000000000000000000000000000000000000000000229 186.0
TH2_k127_5756228_4 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000001974 155.0
TH2_k127_5756228_6 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000004533 64.0
TH2_k127_5756228_7 Protein of unknown function (DUF2905) - - - 0.0009594 44.0
TH2_k127_5756460_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 555.0
TH2_k127_5756460_1 PFAM ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000015 302.0
TH2_k127_5756460_2 ABC transporter transmembrane region K06147 - - 0.0000000000000000000001143 99.0
TH2_k127_5762332_0 EamA-like transporter family - - - 0.000000000000000000000000000001743 133.0
TH2_k127_5764576_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 8.659e-235 737.0
TH2_k127_5764576_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004125 242.0
TH2_k127_5764576_2 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.0000000000000000000000000001578 117.0
TH2_k127_5764576_3 sequence-specific DNA binding K07726 - - 0.000000000000000000000001095 111.0
TH2_k127_5764576_4 - - - - 0.000000000000001985 82.0
TH2_k127_5764576_5 PFAM Plasmid stabilisation system protein - - - 0.000000000000007452 75.0
TH2_k127_5764576_6 Protein of unknown function (DUF3592) - - - 0.000000000000008128 87.0
TH2_k127_5764576_7 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0003331 51.0
TH2_k127_5765315_0 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000004129 195.0
TH2_k127_5765315_1 nucleotidyltransferase activity - - - 0.000008046 56.0
TH2_k127_5765315_2 nucleotidyltransferase activity - - - 0.00002748 51.0
TH2_k127_5775877_0 branched-chain-amino-acid transaminase activity K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 334.0
TH2_k127_5775877_1 COG2301 Citrate lyase beta subunit K01644,K19281,K19282 GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046487,GO:0046872,GO:0046912,GO:0050083,GO:0071704 3.1.2.30,4.1.3.24,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000001203 263.0
TH2_k127_5775877_2 Orn DAP Arg decarboxylase K01586 - 4.1.1.20 0.00000000000000000000003289 102.0
TH2_k127_5775877_3 Glycosyltransferase sugar-binding region containing DXD motif - - - 0.000001455 56.0
TH2_k127_5804007_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 314.0
TH2_k127_5804007_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008611 274.0
TH2_k127_5804007_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000001455 220.0
TH2_k127_5804007_3 Protein of unknown function (DUF2851) - - - 0.000000000000000000000000000000000000000000000003758 192.0
TH2_k127_5804007_4 transport system involved in gliding motility, auxiliary K01992 - - 0.0000000000000000000000000000000000000000000001273 192.0
TH2_k127_5804007_5 transport system K01992 - - 0.00000000000000000000000001595 128.0
TH2_k127_5804007_6 Domain of unknown function (DUF4340) - - - 0.00000000000002144 87.0
TH2_k127_5814774_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007938 286.0
TH2_k127_5814774_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000003178 88.0
TH2_k127_5814774_2 PFAM S-layer homology domain - - - 0.0002332 50.0
TH2_k127_5822770_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 383.0
TH2_k127_5822770_1 Cytidylate kinase-like family K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000167 176.0
TH2_k127_5822770_2 Pseudouridine synthase K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000003135 182.0
TH2_k127_5822770_3 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000001806 177.0
TH2_k127_5822770_4 Transcription elongation factor, N-terminal - - - 0.00000000000000000000000000000000000001093 166.0
TH2_k127_5822770_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000002146 109.0
TH2_k127_5822990_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.00000000000000000000000000000000000000000000000000000000000000000002523 253.0
TH2_k127_5822990_1 Heparinase II/III-like protein - - - 0.000002737 61.0
TH2_k127_5827273_0 SNF2 family N-terminal domain - - - 9.829e-212 690.0
TH2_k127_5836634_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 439.0
TH2_k127_5836634_1 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.00000000000000000439 95.0
TH2_k127_585703_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 503.0
TH2_k127_585703_1 stage 0 sporulation protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000002537 211.0
TH2_k127_585703_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000005234 194.0
TH2_k127_585703_3 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000005951 199.0
TH2_k127_585703_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000003411 190.0
TH2_k127_585703_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000005378 185.0
TH2_k127_585703_6 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000006064 162.0
TH2_k127_585703_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000001266 124.0
TH2_k127_585703_8 pfkB family carbohydrate kinase K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.0003313 51.0
TH2_k127_5877983_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 317.0
TH2_k127_5877983_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0009616 50.0
TH2_k127_5891476_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005415 269.0
TH2_k127_5891476_1 Alpha mannosidase, middle domain - - - 0.000000000000000000000000002743 130.0
TH2_k127_5922612_0 Elongation factor Tu domain 2 K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 404.0
TH2_k127_5922612_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 315.0
TH2_k127_5922612_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000001122 214.0
TH2_k127_5922612_3 4Fe-4S binding domain - - - 0.0000000000000000000001653 109.0
TH2_k127_5922612_4 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00001286 48.0
TH2_k127_5935836_0 ATPase (AAA superfamily) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 404.0
TH2_k127_5935836_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 323.0
TH2_k127_5935836_2 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.00000000000000000000000000000000000000000000000000000000000006532 222.0
TH2_k127_5935836_3 peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000009073 199.0
TH2_k127_5935836_4 Rhodanese Homology Domain - - - 0.00000000000000002282 87.0
TH2_k127_5940045_0 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000002545 181.0
TH2_k127_5940045_1 Parallel beta-helix repeats - - - 0.0000000000000000000000007683 119.0
TH2_k127_5951864_0 Uncharacterized protein conserved in bacteria (DUF2264) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009875 456.0
TH2_k127_5951864_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000001558 144.0
TH2_k127_5996739_0 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009391 461.0
TH2_k127_5996739_1 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 292.0
TH2_k127_5996739_2 Large extracellular alpha-helical protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004577 234.0
TH2_k127_5996739_3 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000006103 224.0
TH2_k127_5996739_4 - - - - 0.0000000000000000000000000000000000000000000000000006137 210.0
TH2_k127_6024223_0 carbohydrate binding - - - 0.00000000000000000000000009655 121.0
TH2_k127_6024223_1 HEAT repeats K00239 - 1.3.5.1,1.3.5.4 0.00004431 56.0
TH2_k127_6024759_0 Belongs to the argininosuccinate synthase family. Type K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 541.0
TH2_k127_6024759_1 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 382.0
TH2_k127_6024759_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000006929 231.0
TH2_k127_6024759_3 Phosphomethylpyrimidine kinase K00941 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008902,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000005786 227.0
TH2_k127_6024759_4 galactokinase activity K00849 GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 0.000000000000000004971 87.0
TH2_k127_6071667_0 - K07221 - - 0.0000000000000000000000000000000000000000002455 168.0
TH2_k127_6071667_1 - - - - 0.000000000000000000000000000000000001261 144.0
TH2_k127_6071667_2 Arylsulfatase - - - 0.00000000000000000000000000000000002645 139.0
TH2_k127_6071667_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000001514 106.0
TH2_k127_607702_0 sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000987 498.0
TH2_k127_607702_1 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 364.0
TH2_k127_607702_2 Beta-galactosidase - - - 0.000000000000009422 78.0
TH2_k127_607702_3 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.00000000575 67.0
TH2_k127_6078828_0 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 419.0
TH2_k127_6078828_1 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 383.0
TH2_k127_6078828_2 ThiF family K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000005601 240.0
TH2_k127_6078828_3 PIN domain - - - 0.0000000000000000000000000000000000309 142.0
TH2_k127_6078828_4 PilT protein domain protein - - - 0.000000000007691 73.0
TH2_k127_6078828_5 - - - - 0.000000001044 63.0
TH2_k127_6078828_6 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000002732 60.0
TH2_k127_6078828_7 Bacterial antitoxin of type II TA system, VapB - - - 0.0002392 47.0
TH2_k127_6085595_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 574.0
TH2_k127_6085595_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001094 273.0
TH2_k127_6085595_2 Transcriptional regulator K13643 - - 0.00000000000000000001181 97.0
TH2_k127_6112939_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001766 263.0
TH2_k127_6112939_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000007206 228.0
TH2_k127_6112939_2 phosphorelay sensor kinase activity K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000327 149.0
TH2_k127_6112939_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000006555 125.0
TH2_k127_6120686_0 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 296.0
TH2_k127_6120686_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.00000000000000000000000000000000000000000000000000000000000000000001709 262.0
TH2_k127_6120686_2 PFAM UvrB UvrC protein K19411 - - 0.0000000000000000000000000002152 122.0
TH2_k127_6120686_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000001977 108.0
TH2_k127_6138162_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 416.0
TH2_k127_6152344_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 434.0
TH2_k127_6152344_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 325.0
TH2_k127_6152344_2 Plasmid stabilization system - - - 0.00000000001337 65.0
TH2_k127_6152344_3 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00001442 49.0
TH2_k127_6152344_4 Putative addiction module component - - - 0.00008419 48.0
TH2_k127_61588_0 Pectate lyase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000004719 205.0
TH2_k127_6167841_0 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 461.0
TH2_k127_6167841_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 325.0
TH2_k127_6194818_0 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000002564 145.0
TH2_k127_6194818_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000001863 132.0
TH2_k127_6194818_2 Rhodanese Homology Domain - - - 0.00000000000000000001191 106.0
TH2_k127_6247459_0 carbohydrate transport K02027,K10117,K17318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003217 282.0
TH2_k127_6247459_1 Binding-protein-dependent transport system inner membrane component K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003797 268.0
TH2_k127_6247459_2 Belongs to the glycosyl hydrolase 31 family - - - 0.00000000000000000000000000000000000000000000000000000000000000221 239.0
TH2_k127_6265344_0 Macrocin-O-methyltransferase (TylF) - - - 0.000000000000000000000000000000000004691 146.0
TH2_k127_6265344_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000009631 134.0
TH2_k127_6265344_2 amine dehydrogenase activity - - - 0.0002417 53.0
TH2_k127_6267009_0 SigmaW regulon antibacterial - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 365.0
TH2_k127_6267009_1 Belongs to the MurCDEF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 302.0
TH2_k127_6267009_2 - K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008941 254.0
TH2_k127_6267009_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000002633 158.0
TH2_k127_6267009_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.0000000000000000000000283 104.0
TH2_k127_6267009_5 COG1030 Membrane-bound serine protease (ClpP class) K07403 - - 0.000000000000002667 82.0
TH2_k127_6275655_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004382 269.0
TH2_k127_6275655_1 PFAM Xylose isomerase domain-containing protein TIM barrel - - - 0.000000000000000000000000000000000000000000006966 172.0
TH2_k127_6301963_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 533.0
TH2_k127_6301963_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 492.0
TH2_k127_6301963_2 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 422.0
TH2_k127_6301963_3 TIGRFAM histidinol phosphate phosphatase HisJ family K04486 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 0.00000000000000000000000000000000000000000000114 171.0
TH2_k127_6319479_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 307.0
TH2_k127_6319479_1 diguanylate cyclase - - - 0.00000000000000008157 86.0
TH2_k127_6328517_0 transposition, DNA-mediated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 345.0
TH2_k127_6328517_1 Domain of unknown function (DUF4091) - - - 0.00000000002536 76.0
TH2_k127_6354764_0 ZIP Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 398.0
TH2_k127_6354764_1 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000005363 219.0
TH2_k127_6354764_2 PFAM band 7 protein - - - 0.000000000000000003745 98.0
TH2_k127_635637_0 phospholipid glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 6.662e-246 784.0
TH2_k127_6400619_0 - - - - 1.245e-246 795.0
TH2_k127_6400619_1 Psort location Cytoplasmic, score 8.96 - - - 0.00001253 56.0
TH2_k127_6400619_2 Glycosyl transferases group 1 - - - 0.00002937 50.0
TH2_k127_6404344_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000001003 242.0
TH2_k127_6404344_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000002801 229.0
TH2_k127_6448480_0 Large extracellular alpha-helical protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008668 256.0
TH2_k127_6448480_1 Large extracellular alpha-helical protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004268 249.0
TH2_k127_6480309_0 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 447.0
TH2_k127_6480309_1 KDPG and KHG aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000002733 231.0
TH2_k127_6480309_2 glutamate synthase, small subunit K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000003146 138.0
TH2_k127_6514788_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009722 414.0
TH2_k127_6514788_1 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 359.0
TH2_k127_6514788_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000001357 222.0
TH2_k127_6514788_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.00000001682 67.0
TH2_k127_6562963_0 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 449.0
TH2_k127_6562963_1 aminotransferase class V K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000000000000000000001483 233.0
TH2_k127_6585934_0 metallocarboxypeptidase activity K14054 - - 0.000000000000000000000000000000000000000000000000000000003681 210.0
TH2_k127_6585934_1 - - - - 0.00000000000000000000000000002222 135.0
TH2_k127_6586444_0 amine dehydrogenase activity - - - 0.000000000000000001029 101.0
TH2_k127_6595107_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K01791,K02472 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046378,GO:0055114,GO:0071704,GO:0089714,GO:1901135,GO:1901137,GO:1901576 1.1.1.336,5.1.3.14 1.592e-196 619.0
TH2_k127_6595107_1 Aminotransferase K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 474.0
TH2_k127_6597959_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 411.0
TH2_k127_6597959_1 PFAM ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 373.0
TH2_k127_6597959_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000003008 147.0
TH2_k127_6597959_3 Protein of unknown function DUF72 - - - 0.00000000000000001095 92.0
TH2_k127_6600288_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 347.0
TH2_k127_6600288_1 Domain of unknown function (DUF4338) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 299.0
TH2_k127_6604017_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01190 - 3.2.1.23 1.142e-196 638.0
TH2_k127_6604017_1 chorismate mutase K01850 - 5.4.99.5 0.0000000000000000000000000000000000000000000000000000008117 199.0
TH2_k127_6604017_2 May be involved in recombination K03554 - - 0.000000000000000000000000000000000000000000000000000006848 204.0
TH2_k127_6604017_4 Protein conserved in bacteria K09764 - - 0.0000000000001285 77.0
TH2_k127_6610682_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 9.177e-224 705.0
TH2_k127_6610682_1 - - - - 0.00000000000000000000000000000000000000000000000005368 196.0
TH2_k127_6610682_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00002144 51.0
TH2_k127_6634714_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000000000000000000000000000000009514 215.0
TH2_k127_6634714_1 Vault protein inter-alpha-trypsin domain K07114 - - 0.0000000000000000000000000000000000005648 151.0
TH2_k127_6634714_2 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372,K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000003274 139.0
TH2_k127_6660856_0 Sulfatase - - - 4.176e-218 688.0
TH2_k127_6660856_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000006195 213.0
TH2_k127_6691570_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.074e-205 644.0
TH2_k127_6691570_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 348.0
TH2_k127_6691570_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004214 247.0
TH2_k127_6691570_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000004928 236.0
TH2_k127_6691570_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000008139 210.0
TH2_k127_6691570_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000001883 74.0
TH2_k127_6691570_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0002582 46.0
TH2_k127_6692216_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.471e-228 720.0
TH2_k127_6692216_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.386e-202 646.0
TH2_k127_6692216_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000002367 199.0
TH2_k127_6692216_3 - - - - 0.0000000000000000000000001133 111.0
TH2_k127_6692216_4 PFAM Integral membrane protein TerC K05794 - - 0.000000000000002135 81.0
TH2_k127_6703439_0 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 564.0
TH2_k127_6703439_1 NQR2, RnfD, RnfE family K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 353.0
TH2_k127_6703439_2 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000447 257.0
TH2_k127_6703439_3 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000005704 159.0
TH2_k127_6703439_4 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000347 95.0
TH2_k127_6703439_5 Catalyzes the insertion of Co(2 ) into sirohydrochlorin K02190 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0016829,GO:0016852,GO:0020037,GO:0022607,GO:0042597,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050897,GO:0051259,GO:0051262,GO:0051266,GO:0065003,GO:0071840,GO:0097159,GO:1901363 4.99.1.3 0.0000000008907 63.0
TH2_k127_6717448_0 PFAM Radical SAM K22226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 581.0
TH2_k127_6717448_1 SMART Elongator protein 3 MiaB NifB K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 359.0
TH2_k127_6717448_10 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000004823 155.0
TH2_k127_6717448_11 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000009029 126.0
TH2_k127_6717448_12 - - - - 0.000000000000000000000000000001036 138.0
TH2_k127_6717448_13 amine dehydrogenase activity K21449 - - 0.000000000000000000000000000004116 127.0
TH2_k127_6717448_14 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000186 106.0
TH2_k127_6717448_16 ResB-like family - - - 0.00000000000000000000001922 114.0
TH2_k127_6717448_17 Cytochrome c assembly protein - - - 0.00000000000000000003994 102.0
TH2_k127_6717448_18 HD domain K07814 - - 0.0000000000000003079 87.0
TH2_k127_6717448_19 helix_turn_helix, arabinose operon control protein - - - 0.00000000000002704 85.0
TH2_k127_6717448_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 343.0
TH2_k127_6717448_20 Prokaryotic cytochrome b561 - - - 0.0000002176 59.0
TH2_k127_6717448_21 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.000002281 53.0
TH2_k127_6717448_22 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway K01845 - 5.4.3.8 0.0002688 48.0
TH2_k127_6717448_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001276 293.0
TH2_k127_6717448_4 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002841 261.0
TH2_k127_6717448_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000005566 271.0
TH2_k127_6717448_6 Tetrapyrrole (Corrin/Porphyrin) Methylases K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000007727 252.0
TH2_k127_6717448_7 transcriptional regulator, AsnC family - - - 0.000000000000000000000000000000000000000000000000000000000000001584 230.0
TH2_k127_6717448_8 4 iron, 4 sulfur cluster binding K00184,K08358 - - 0.000000000000000000000000000000000000000000000000000000000000006694 228.0
TH2_k127_6717448_9 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000008033 206.0
TH2_k127_6721035_0 ATPase family associated with various cellular activities (AAA) K03924,K07452 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 467.0
TH2_k127_6721035_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000001331 153.0
TH2_k127_6721035_2 Protein of unknown function DUF58 - - - 0.00000000002352 66.0
TH2_k127_6721035_3 Sigma-70 region 2 - - - 0.0000000001315 75.0
TH2_k127_6721035_4 Sigma-70, region 4 K03088 - - 0.00000002043 58.0
TH2_k127_6721035_5 iron ion homeostasis K07165 - - 0.00007451 54.0
TH2_k127_6722061_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 301.0
TH2_k127_6722061_1 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001615 261.0
TH2_k127_6722662_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 585.0
TH2_k127_6722662_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 505.0
TH2_k127_6722662_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000003289 134.0
TH2_k127_6722662_3 - - - - 0.0000001807 55.0
TH2_k127_6766196_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 435.0
TH2_k127_6766196_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 423.0
TH2_k127_6766196_2 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 401.0
TH2_k127_6766196_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000009621 180.0
TH2_k127_6766196_4 Preprotein translocase subunit K03210 - - 0.000000000000000000001432 98.0
TH2_k127_6774590_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 293.0
TH2_k127_6774590_1 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 288.0
TH2_k127_6774590_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006516 295.0
TH2_k127_6782669_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 377.0
TH2_k127_6782669_1 Protein of unknown function (DUF1016) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 360.0
TH2_k127_6782669_2 COGs COG5573 nucleic-acid-binding protein contains PIN domain - - - 0.000000000000000000000000000000007095 132.0
TH2_k127_6782669_3 - - - - 0.00000000000000000005519 91.0
TH2_k127_6782669_4 radical SAM domain protein - - - 0.0000000000002745 81.0
TH2_k127_6782669_5 nuclease - - - 0.00003364 50.0
TH2_k127_6803684_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000006905 248.0
TH2_k127_6809618_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 370.0
TH2_k127_6809618_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 327.0
TH2_k127_6809618_2 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000003346 244.0
TH2_k127_6809618_3 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.000000000000000000000000000000000000000000000000000007157 219.0
TH2_k127_6809618_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000001575 202.0
TH2_k127_6809618_5 Protein of unknown function DUF86 K07075 - - 0.0000000000000000000000000000000000000000000004316 179.0
TH2_k127_6809618_6 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000001474 149.0
TH2_k127_6811976_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 359.0
TH2_k127_6811976_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000001335 281.0
TH2_k127_6811976_2 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.00000000000000000000000000000000000000000001724 181.0
TH2_k127_6811976_3 Phosphopantetheine attachment site - - - 0.00000000000000000000955 96.0
TH2_k127_6811976_4 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000003913 95.0
TH2_k127_6811976_5 Domain of unknown function (DUF1736) - GO:0001763,GO:0002009,GO:0003401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006950,GO:0007275,GO:0008150,GO:0009653,GO:0009791,GO:0009887,GO:0009888,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0012505,GO:0019222,GO:0030154,GO:0030162,GO:0030323,GO:0030324,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033554,GO:0034976,GO:0035239,GO:0035295,GO:0040007,GO:0042176,GO:0042692,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045732,GO:0045862,GO:0048286,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048729,GO:0048731,GO:0048747,GO:0048754,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051716,GO:0055001,GO:0055002,GO:0060255,GO:0060425,GO:0060429,GO:0060441,GO:0060447,GO:0060541,GO:0060560,GO:0060562,GO:0060602,GO:0061061,GO:0061136,GO:0061138,GO:0065007,GO:0080090,GO:1901800,GO:1903050,GO:1903052,GO:1903362,GO:1903364 - 0.000000000000005688 83.0
TH2_k127_6811976_6 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000008993 68.0
TH2_k127_6811976_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00003948 52.0
TH2_k127_6812773_0 Bacterial type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000000000000000000000000000111 236.0
TH2_k127_6812773_1 Protein of unknown function (DUF1559) - - - 0.0000006956 61.0
TH2_k127_6812773_2 DNA helicase K03657 - 3.6.4.12 0.00006458 56.0
TH2_k127_6814973_0 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000000000009731 119.0
TH2_k127_6824267_0 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.000000000006737 80.0
TH2_k127_6824267_1 Outer membrane lipoprotein - - - 0.0001867 56.0
TH2_k127_6829644_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 572.0
TH2_k127_6855974_0 PFAM AIG2 family protein K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000001737 211.0
TH2_k127_6855974_1 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000000000004125 167.0
TH2_k127_6855974_2 PFAM Response regulator receiver domain K07689 - - 0.0000000000000000000000000000000000000000002452 166.0
TH2_k127_6855974_3 - - - - 0.0000000000000000000000000000000003767 153.0
TH2_k127_6855974_4 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000001813 127.0
TH2_k127_6855974_5 response to nickel cation K07722 - - 0.0000000000000000004149 89.0
TH2_k127_6855974_6 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.0000000009324 70.0
TH2_k127_6869295_0 Transmembrane and tetratricopeptide repeat containing 1 - - - 0.000001957 61.0
TH2_k127_6869295_1 Tetratricopeptide repeat - - - 0.00002364 57.0
TH2_k127_6872814_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 340.0
TH2_k127_6872814_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000009015 185.0
TH2_k127_6872814_2 serine threonine protein kinase - - - 0.000000001091 70.0
TH2_k127_6872814_3 PFAM Glycoside hydrolase, family 38 K01191,K15524 - 3.2.1.170,3.2.1.24 0.00000002506 61.0
TH2_k127_6876669_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.919e-215 679.0
TH2_k127_6876669_1 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001281 230.0
TH2_k127_6876669_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000003822 182.0
TH2_k127_6876669_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000971 95.0
TH2_k127_6876669_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00003257 56.0
TH2_k127_6877203_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 399.0
TH2_k127_6877203_1 PFAM Phosphatidic acid phosphatase type 2 haloperoxidase - - - 0.00000000000000000000000000000000000000000000000000000004581 222.0
TH2_k127_6877203_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000002299 98.0
TH2_k127_6884103_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.88e-199 635.0
TH2_k127_6884103_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 620.0
TH2_k127_6884103_10 Belongs to the SUA5 family K07566 - 2.7.7.87 0.00000000000000000000000000000001448 136.0
TH2_k127_6884103_11 sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.0000000000000000000000000001625 123.0
TH2_k127_6884103_12 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0008791 47.0
TH2_k127_6884103_2 Proton-conducting membrane transporter K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 588.0
TH2_k127_6884103_3 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 337.0
TH2_k127_6884103_4 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 331.0
TH2_k127_6884103_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 305.0
TH2_k127_6884103_6 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003196 272.0
TH2_k127_6884103_7 SMART zinc finger, CDGSH-type domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002638 259.0
TH2_k127_6884103_8 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000004012 238.0
TH2_k127_6884103_9 Hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000001498 186.0
TH2_k127_6903968_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000002809 234.0
TH2_k127_6903968_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000002246 96.0
TH2_k127_6903968_2 COG1520 FOG WD40-like repeat - - - 0.00000003825 67.0
TH2_k127_6910688_0 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006831 259.0
TH2_k127_6910688_1 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000003198 239.0
TH2_k127_6910688_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000002168 197.0
TH2_k127_6910688_3 cellular response to DNA damage stimulus - GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.000000000000000000000000000000000001337 145.0
TH2_k127_6910688_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000001686 64.0
TH2_k127_6911796_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 526.0
TH2_k127_6911796_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 370.0
TH2_k127_6911796_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03471 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007007 282.0
TH2_k127_6911796_3 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000008334 239.0
TH2_k127_6911796_4 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000142 215.0
TH2_k127_6911796_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000002074 173.0
TH2_k127_6911796_6 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000008078 112.0
TH2_k127_6920707_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008567 522.0
TH2_k127_6920707_1 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 411.0
TH2_k127_6920707_2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.000000000000000000002306 108.0
TH2_k127_6920707_3 Protein of unknown function (DUF1648) - - - 0.000000000000005057 88.0
TH2_k127_6923250_0 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.00000000000000006055 94.0
TH2_k127_6923250_1 PFAM transposase, IS4 family protein - - - 0.0000000001647 70.0
TH2_k127_6927197_0 COGs COG1501 Alpha-glucosidase family 31 of glycosyl hydrolase K01811 - 3.2.1.177 0.000000000000000000000000000000000000000000000000000000000000000004994 245.0
TH2_k127_6927197_1 glucan 1,4-alpha-glucosidase activity - - - 0.000000000000000000000000000000001453 147.0
TH2_k127_6928771_0 Formate--tetrahydrofolate ligase K00288,K01938 GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.5,3.5.4.9,6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000005593 233.0
TH2_k127_6928771_1 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000000001216 118.0
TH2_k127_6928771_2 Parallel beta-helix repeats - - - 0.0000000000000000001121 94.0
TH2_k127_6929856_0 capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.000000000000000000000000000000000000000006367 164.0
TH2_k127_6929856_1 O-Antigen ligase - - - 0.0000000000006809 84.0
TH2_k127_6942433_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 417.0
TH2_k127_6942433_1 self proteolysis K00525,K01952 - 1.17.4.1,6.3.5.3 0.0000000005064 64.0
TH2_k127_6942433_2 Autotransporter beta-domain - - - 0.0000139 57.0
TH2_k127_6943871_0 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 334.0
TH2_k127_6943871_1 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000003306 151.0
TH2_k127_6943871_2 - - - - 0.000000000000000000000000000005575 122.0
TH2_k127_6951690_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 534.0
TH2_k127_6951690_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 490.0
TH2_k127_6951690_2 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003478 279.0
TH2_k127_6951690_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000001166 247.0
TH2_k127_6951690_4 Histidine kinase - - - 0.00000000000000000000000001871 115.0
TH2_k127_6955251_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 619.0
TH2_k127_6955251_1 Pfam:DUF303 K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000002073 240.0
TH2_k127_6956212_0 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000621 214.0
TH2_k127_6956212_1 Transporter associated domain K03699 - - 0.000000000000000000000000000000000005695 157.0
TH2_k127_6956212_2 Cytidylate kinase-like family K00945 - 2.7.4.25 0.00000000006302 72.0
TH2_k127_6956212_3 beta-propeller repeat - - - 0.00002046 57.0
TH2_k127_6964477_0 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 377.0
TH2_k127_6974297_0 Lysine-2,3-aminomutase K01843,K19814 - 5.4.3.2,5.4.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 304.0
TH2_k127_6974297_1 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007417 295.0
TH2_k127_6974297_2 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000002685 166.0
TH2_k127_6974297_3 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.00000000000003687 78.0
TH2_k127_6974297_4 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000002445 66.0
TH2_k127_6975900_0 - - - - 0.00000000000000000000000000000000000000000000000001015 205.0
TH2_k127_6975900_1 carbohydrate binding - - - 0.000000000001136 76.0
TH2_k127_6975900_2 COG1520 FOG WD40-like repeat - - - 0.0000001079 67.0
TH2_k127_6977981_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 417.0
TH2_k127_6977981_1 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006599 279.0
TH2_k127_6977981_2 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000001019 159.0
TH2_k127_6979244_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 526.0
TH2_k127_6979244_1 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 385.0
TH2_k127_6985024_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 509.0
TH2_k127_6985024_1 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 454.0
TH2_k127_6985024_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 292.0
TH2_k127_6985024_3 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000004523 57.0
TH2_k127_7046089_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000004638 106.0
TH2_k127_7046089_1 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000003452 91.0
TH2_k127_7046089_2 - - - - 0.000000001068 64.0
TH2_k127_7054660_0 Involved in the tonB-independent uptake of proteins K03641 - - 4.203e-244 775.0
TH2_k127_7054660_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000005068 202.0
TH2_k127_7054660_2 - - - - 0.00000000000000000000000000000000000000000000000001114 201.0
TH2_k127_7054660_3 Flavin containing amine oxidoreductase K09835,K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,5.2.1.13 0.0000000000003611 83.0
TH2_k127_7054660_4 Flavin containing amine oxidoreductase K09835,K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,5.2.1.13 0.0000000001673 72.0
TH2_k127_7071433_0 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 391.0
TH2_k127_7071433_1 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000625 252.0
TH2_k127_7071433_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000002812 214.0
TH2_k127_7071433_3 cell wall hydrolase K01448 - 3.5.1.28 0.000000000000000000000000000000000000004913 159.0
TH2_k127_7071433_4 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000004507 152.0
TH2_k127_7071433_5 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.000000000000000006702 97.0
TH2_k127_7151287_0 Band 7 protein K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 550.0
TH2_k127_7151287_1 Uncharacterised ACR (DUF711) K09157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 554.0
TH2_k127_7151287_2 phosphoserine phosphatase activity K00003,K07166 - 1.1.1.3 0.00000000000001005 82.0
TH2_k127_7151287_3 cellular response to DNA damage stimulus - GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.00000008285 55.0
TH2_k127_7157491_0 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 530.0
TH2_k127_7157491_1 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000004644 216.0
TH2_k127_7157491_2 Organic solvent tolerance protein OstA - - - 0.0000000005022 72.0
TH2_k127_7157852_0 Family 4 glycosyl hydrolase K01222,K07406 - 3.2.1.22,3.2.1.86 2.934e-204 645.0
TH2_k127_7157852_1 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 357.0
TH2_k127_7157852_2 Xylose isomerase-like TIM barrel K22233 - - 0.000000000000000000000000000000001112 141.0
TH2_k127_7157852_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000003395 121.0
TH2_k127_7157852_4 P-loop containing nucleoside triphosphate hydrolase protein K15918 GO:0000166,GO:0003674,GO:0003824,GO:0004849,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042455,GO:0043094,GO:0043097,GO:0043167,GO:0043168,GO:0043174,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.31 0.00000000000000000000000001631 124.0
TH2_k127_7158524_0 aconitate hydratase activity K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 459.0
TH2_k127_7158524_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000002197 147.0
TH2_k127_7158524_2 positive regulation of growth - - - 0.0000000000000001197 83.0
TH2_k127_7165216_0 Male sterility protein K12454 - 5.1.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 514.0
TH2_k127_7165216_1 Epimerase dehydratase K01784,K12454 - 5.1.3.10,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 360.0
TH2_k127_7165216_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 336.0
TH2_k127_7165216_3 transferase activity, transferring glycosyl groups K20444 - - 0.000000000000000000000000000000000000000000000000000001616 207.0
TH2_k127_7179688_0 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 349.0
TH2_k127_7179688_1 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000000000000000002369 164.0
TH2_k127_7179688_2 Metal-dependent hydrolase HDOD - - - 0.00000000000000000002677 105.0
TH2_k127_7210830_0 Belongs to the aldehyde dehydrogenase family K00128,K00129 - 1.2.1.3,1.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 449.0
TH2_k127_7210830_1 all-trans-retinol 13,14-reductase activity K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 382.0
TH2_k127_7210830_2 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000117 139.0
TH2_k127_7221024_0 Hypothetical glycosyl hydrolase 6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 606.0
TH2_k127_7221024_1 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 557.0
TH2_k127_7221024_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000005832 110.0
TH2_k127_7221024_11 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000003154 106.0
TH2_k127_7221024_12 - - - - 0.000000000000000000004408 104.0
TH2_k127_7221024_13 PIN domain - - - 0.000000000000000000005996 99.0
TH2_k127_7221024_14 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.000000000000001224 91.0
TH2_k127_7221024_15 Glycosyl transferase 4-like domain - - - 0.00000000000322 79.0
TH2_k127_7221024_16 positive regulation of growth - GO:0006417,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0040007,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0080090,GO:2000112 - 0.0000000041 61.0
TH2_k127_7221024_17 Acetyltransferase (GNAT) domain - - - 0.00001112 54.0
TH2_k127_7221024_18 PIN domain K18828 - - 0.00001774 47.0
TH2_k127_7221024_2 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 378.0
TH2_k127_7221024_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 350.0
TH2_k127_7221024_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 342.0
TH2_k127_7221024_5 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000002087 240.0
TH2_k127_7221024_6 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000002473 216.0
TH2_k127_7221024_7 Carboxylesterase family - - - 0.0000000000000000000000000000000000006205 161.0
TH2_k127_7221024_8 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000138 115.0
TH2_k127_7221024_9 Glycosyl transferases group 1 - - - 0.00000000000000000000000002834 112.0
TH2_k127_7238701_0 domain, Protein K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 612.0
TH2_k127_7238701_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 584.0
TH2_k127_7238701_2 anaphase-promoting complex binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008119 522.0
TH2_k127_7238701_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 382.0
TH2_k127_7238701_4 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term K17108 - 3.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 350.0
TH2_k127_7238701_5 PFAM sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001473 272.0
TH2_k127_7238701_6 CHAD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000004181 211.0
TH2_k127_7238701_7 Cysteine-rich secretory protein family - - - 0.00000000000000000008891 93.0
TH2_k127_7321199_0 PFAM Sulfatase - - - 7.656e-212 686.0
TH2_k127_7321199_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 501.0
TH2_k127_7321199_2 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 419.0
TH2_k127_7321199_3 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 388.0
TH2_k127_7321199_5 Involved in the anomeric conversion of L-rhamnose K03534 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.1.3.32 0.00000000000000000000000000000000000000000005537 162.0
TH2_k127_7321199_6 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000119 129.0
TH2_k127_7321199_7 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000000000002484 111.0
TH2_k127_7321199_8 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000005762 75.0
TH2_k127_7326588_0 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 419.0
TH2_k127_7326588_1 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000004358 241.0
TH2_k127_7335183_0 Domain of unknown function K03737 - 1.2.7.1 0.0 1563.0
TH2_k127_7335183_1 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009841 485.0
TH2_k127_7335183_2 beta-N-acetylhexosaminidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 353.0
TH2_k127_7335183_3 Diguanylate cyclase - - - 0.000000008728 68.0
TH2_k127_7335183_4 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000003792 61.0
TH2_k127_7350406_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007651 331.0
TH2_k127_7350406_1 - - - - 0.00000000000000000000002165 106.0
TH2_k127_7375314_0 Glycosyl transferase family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002098 276.0
TH2_k127_7375314_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000001391 209.0
TH2_k127_7376089_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000002854 214.0
TH2_k127_7376089_1 G-rich domain on putative tyrosine kinase K16692 GO:0000271,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0036211,GO:0038083,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046377,GO:0046777,GO:0071704,GO:0071944,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 - 0.00000000000000000000000000000000002232 155.0
TH2_k127_7376089_2 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000001932 145.0
TH2_k127_7376089_3 export protein K01991 - - 0.000000000000000000000000000000495 136.0
TH2_k127_7376089_4 Domain of unknown function DUF11 - - - 0.00000000000000000828 96.0
TH2_k127_7376089_5 Phosphopantetheine attachment site K02078 - - 0.00000000000001554 86.0
TH2_k127_7384250_0 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000005546 225.0
TH2_k127_7384250_1 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000002291 166.0
TH2_k127_7384250_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000002082 134.0
TH2_k127_7384250_3 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000001334 100.0
TH2_k127_7396502_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 355.0
TH2_k127_7396502_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 287.0
TH2_k127_7396502_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000003639 231.0
TH2_k127_7396502_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000004217 166.0
TH2_k127_7396502_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000005824 161.0
TH2_k127_7396502_5 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000004059 63.0
TH2_k127_7402819_0 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005061 252.0
TH2_k127_7402819_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000003078 155.0
TH2_k127_7407270_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000001369 145.0
TH2_k127_7407270_1 PEGA domain - - - 0.0000000000000000000000000127 119.0
TH2_k127_7407270_2 cell division protein FtsK K03466 - - 0.00000000002229 76.0
TH2_k127_742440_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 302.0
TH2_k127_742440_1 ribonuclease activity - - - 0.00000000000000000000000000001097 121.0
TH2_k127_742440_2 toxin-antitoxin pair type II binding - - - 0.0000000000000004479 80.0
TH2_k127_7448996_0 Binding-protein-dependent transport system inner membrane component K15582 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001047 275.0
TH2_k127_7448996_1 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000221 205.0
TH2_k127_7459547_0 BlaR1 peptidase M56 - - - 0.00000000000004562 85.0
TH2_k127_7459547_1 - - - - 0.0003393 54.0
TH2_k127_7459966_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.689e-195 634.0
TH2_k127_7560417_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0000000000165 77.0
TH2_k127_7560417_1 lyase activity - - - 0.00000000002374 76.0
TH2_k127_7569288_0 Oxaloacetate decarboxylase, alpha subunit K01571,K01960 - 4.1.1.3,6.4.1.1 1.192e-201 638.0
TH2_k127_7569288_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 456.0
TH2_k127_7569288_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004964 259.0
TH2_k127_7569288_3 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000009134 255.0
TH2_k127_7569288_4 Domain of unknown function (DUF1848) - - - 0.00000000000000002745 85.0
TH2_k127_7569288_5 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000003906 80.0
TH2_k127_7613882_0 UDP-glucose pyrophosphorylase K00963 - 2.7.7.9 5.364e-276 867.0
TH2_k127_7613882_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 393.0
TH2_k127_7613882_2 1,7-bisphosphate phosphatase - - - 0.000000000000000000000000000000000000000007452 166.0
TH2_k127_7613882_3 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000001819 89.0
TH2_k127_7613882_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000006976 79.0
TH2_k127_7647431_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 385.0
TH2_k127_7647431_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.00000000000000000000000000000000000000000000000000000000005815 222.0
TH2_k127_7647431_2 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000204 209.0
TH2_k127_7647431_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000003246 194.0
TH2_k127_7647431_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000006689 180.0
TH2_k127_7647431_5 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000006348 97.0
TH2_k127_7647431_6 PFAM PEGA domain - - - 0.000000000000367 78.0
TH2_k127_7656265_0 Phosphoenolpyruvate synthase K01007 - 2.7.9.2 0.0 1070.0
TH2_k127_7656265_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000006949 180.0
TH2_k127_7656265_2 PIN domain K07062 - - 0.00000000000000000000000000000000000001851 150.0
TH2_k127_7656265_3 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000191 141.0
TH2_k127_7656265_4 Psort location K13622 - - 0.000000000000000000000000000000001691 133.0
TH2_k127_7656265_5 dolichyl monophosphate biosynthetic process K00981,K18678 - 2.7.1.182,2.7.7.41 0.000000000000000000000000000003223 138.0
TH2_k127_7656265_6 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000005245 74.0
TH2_k127_7686728_0 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000000002889 215.0
TH2_k127_7686728_1 Domain of unknown function (DUF4184) - - - 0.000000000000000000000000000002116 131.0
TH2_k127_7686728_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000008382 118.0
TH2_k127_7686728_3 Glycosyl transferases group 1 - - - 0.0009868 47.0
TH2_k127_7706216_0 glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 6.218e-213 698.0
TH2_k127_7706216_1 - - - - 0.000000000000000000000000000003179 134.0
TH2_k127_771448_0 PFAM FG-GAP repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000005224 246.0
TH2_k127_771448_1 Peptidase M60-like family - - - 0.00000000000000000000000000000000000000000723 179.0
TH2_k127_771448_2 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000001878 140.0
TH2_k127_771448_3 Concanavalin A-like lectin/glucanases superfamily K12287 - - 0.000000000000000000000004758 121.0
TH2_k127_771448_4 Transcriptional regulator - - - 0.00000002091 59.0
TH2_k127_7763941_0 curli production assembly transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 377.0
TH2_k127_7763941_1 Formyl transferase - - - 0.000000000000000000000000000000000000000000002801 174.0
TH2_k127_7763941_2 PFAM AMP-dependent synthetase and ligase - - - 0.000000004772 64.0
TH2_k127_7770450_0 Bacterial regulatory protein, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 512.0
TH2_k127_7770450_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 303.0
TH2_k127_7770450_2 eight transmembrane protein EpsH - - - 0.0000000000000000000002078 109.0
TH2_k127_7770450_3 COG0457 FOG TPR repeat - - - 0.0003668 48.0
TH2_k127_7789426_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.016e-211 675.0
TH2_k127_7789426_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000007759 196.0
TH2_k127_7789426_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075,K15780 - 2.4.2.8,6.3.4.19 0.000000005287 59.0
TH2_k127_780232_0 Transcriptional regulator IclR - - - 0.00000000000000000000000000000000000000000001351 171.0
TH2_k127_780232_1 Autotransporter beta-domain K19231 - - 0.0000000005124 72.0
TH2_k127_7814371_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 550.0
TH2_k127_7814371_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000008777 108.0
TH2_k127_7814371_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000133 91.0
TH2_k127_7822367_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 377.0
TH2_k127_7822367_1 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000008958 210.0
TH2_k127_7822367_2 Phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000003711 153.0
TH2_k127_7833718_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 293.0
TH2_k127_7833718_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009472 265.0
TH2_k127_7833718_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000009607 103.0
TH2_k127_7833718_3 PIN domain - - - 0.000000000000000002437 90.0
TH2_k127_7833718_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000001993 68.0
TH2_k127_7833718_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000008913 72.0
TH2_k127_7833718_6 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.0009593 44.0
TH2_k127_7837934_0 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 451.0
TH2_k127_7837934_1 PFAM IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000007686 155.0
TH2_k127_7837934_2 methyltransferase - - - 0.00000000000000000000005491 105.0
TH2_k127_7842505_0 Psort location Cytoplasmic, score 8.87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 587.0
TH2_k127_789680_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.412e-200 647.0
TH2_k127_789680_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 492.0
TH2_k127_789680_10 TIGRFAM lipopolysaccharide transport periplasmic protein LptA K09774 - - 0.000007611 51.0
TH2_k127_789680_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 472.0
TH2_k127_789680_3 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 314.0
TH2_k127_789680_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004485 264.0
TH2_k127_789680_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000004232 192.0
TH2_k127_789680_6 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000006096 156.0
TH2_k127_789680_7 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000000002389 105.0
TH2_k127_789680_8 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000003141 66.0
TH2_k127_789680_9 Protein of unknown function (DUF3108) - - - 0.000000008131 66.0
TH2_k127_7900640_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1130.0
TH2_k127_7900640_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000002083 136.0
TH2_k127_7900640_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000009719 126.0
TH2_k127_7900640_3 Glycosyltransferase family 87 - - - 0.0000003954 62.0
TH2_k127_7902578_0 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 1.72e-240 757.0
TH2_k127_7902578_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.129e-194 625.0
TH2_k127_7902578_2 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000002957 251.0
TH2_k127_7902578_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000101 107.0
TH2_k127_7922314_0 AAA domain K02450 - - 0.000000000000000445 89.0
TH2_k127_7922314_1 PFAM Integrase catalytic - - - 0.0000000000000006889 91.0
TH2_k127_7922314_2 Glycosyl transferase family 2 - - - 0.000002971 55.0
TH2_k127_7930746_0 conserved protein (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001072 273.0
TH2_k127_7930746_1 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006795 265.0
TH2_k127_7930746_2 e3 binding domain - - - 0.000000000000000000000000000000000000000000000000000000001265 207.0
TH2_k127_7930746_3 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.0000000000000000000000000000000000000000000000000001119 192.0
TH2_k127_7930746_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000007524 83.0
TH2_k127_7939449_0 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002596 277.0
TH2_k127_7939449_1 - - - - 0.00000000000000000000000000000000000001045 157.0
TH2_k127_7939449_2 phosphocarrier protein HPr K11189 - - 0.0000000002039 64.0
TH2_k127_7939449_3 - - - - 0.0000006596 61.0
TH2_k127_7939449_4 Protein SSUH2 homolog - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0007275,GO:0008150,GO:0009653,GO:0009887,GO:0032501,GO:0032502,GO:0042476,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0048513,GO:0048731,GO:0048856 - 0.00006342 55.0
TH2_k127_7958401_0 magnesium chelatase K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 344.0
TH2_k127_7958401_1 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 342.0
TH2_k127_7958401_2 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000008584 156.0
TH2_k127_7958401_3 Oxidoreductase domain protein - - - 0.000000000000000000000000002596 114.0
TH2_k127_7958401_4 protein some members contain a von Willebrand factor type A vWA domain - - - 0.0000000000000000000000000195 123.0
TH2_k127_7977542_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.000000000000000000000000000000000000000000000000000000000000005146 236.0
TH2_k127_7979177_0 L-rhamnose isomerase activity K00848,K01813 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008270,GO:0008740,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0022607,GO:0030145,GO:0030246,GO:0032991,GO:0033296,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046872,GO:0046914,GO:0048029,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901575 2.7.1.5,5.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 576.0
TH2_k127_7979177_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 388.0
TH2_k127_7979177_2 PFAM Mg2 transporter protein CorA family protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 293.0
TH2_k127_7979177_3 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000006563 151.0
TH2_k127_7979177_4 PFAM glycoside hydrolase family 29 (alpha-L-fucosidase) K01206 - 3.2.1.51 0.00000000000000000000000000000000004067 141.0
TH2_k127_7979177_5 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000003047 55.0
TH2_k127_7979582_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 449.0
TH2_k127_7979582_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 303.0
TH2_k127_7979582_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000001777 190.0
TH2_k127_7994777_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 578.0
TH2_k127_7994777_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000002243 198.0
TH2_k127_7994777_2 - - - - 0.0000000000000000000000000000000000000000000004395 175.0
TH2_k127_8015009_0 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 376.0
TH2_k127_8015009_1 Tetratricopeptide repeat - - - 0.0002535 53.0
TH2_k127_8016543_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 3.548e-195 630.0
TH2_k127_8016543_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 286.0
TH2_k127_8016543_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000001854 210.0
TH2_k127_8016543_3 O-acyltransferase activity K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000000005806 190.0
TH2_k127_8028593_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 447.0
TH2_k127_8028593_1 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 358.0
TH2_k127_8028593_2 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 334.0
TH2_k127_8028593_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000001896 184.0
TH2_k127_8028593_4 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000000001678 130.0
TH2_k127_8028593_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000007701 128.0
TH2_k127_8028593_6 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000002328 107.0
TH2_k127_8028593_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000001902 104.0
TH2_k127_8028593_9 Binds directly to 16S ribosomal RNA K02968 - - 0.00001681 50.0
TH2_k127_8029679_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 378.0
TH2_k127_8029679_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.000000000000000000000000000000000000000000000000000004466 213.0
TH2_k127_8029679_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000001643 168.0
TH2_k127_8029679_3 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000000995 103.0
TH2_k127_8029679_4 - - - - 0.0000001157 62.0
TH2_k127_8035147_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.278e-207 661.0
TH2_k127_8035147_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 430.0
TH2_k127_8035147_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000008699 154.0
TH2_k127_8071333_0 PFAM UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 338.0
TH2_k127_8071333_1 NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 330.0
TH2_k127_8071333_10 - - - - 0.0000001022 59.0
TH2_k127_8071333_2 Aminotransferase class I and II K00639,K00652,K01906 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47,6.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 324.0
TH2_k127_8071333_3 B12 binding domain K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000006588 273.0
TH2_k127_8071333_4 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001602 280.0
TH2_k127_8071333_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003437 270.0
TH2_k127_8071333_6 Butirosin biosynthesis protein H, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000001514 228.0
TH2_k127_8071333_7 lipid kinase activity - - - 0.000000000000000000000000000003584 137.0
TH2_k127_8071333_8 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000007787 129.0
TH2_k127_8071333_9 Phosphopantetheine attachment site K02078 - - 0.000000000002678 70.0
TH2_k127_8103968_0 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000365 171.0
TH2_k127_8103968_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000001227 65.0
TH2_k127_8117579_0 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 529.0
TH2_k127_8117579_1 Protein of unknown function (DUF2959) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007905 264.0
TH2_k127_8117579_3 Protein of unknown function VcgC/VcgE (DUF2780) - - - 0.00000000000000000000000009372 115.0
TH2_k127_8117579_4 gluconolactonase activity - - - 0.000000000000000001821 100.0
TH2_k127_8117579_5 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000001461 82.0
TH2_k127_8117579_6 Nitroreductase family - - - 0.000000000000006501 83.0
TH2_k127_8117579_7 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000228 50.0
TH2_k127_8120934_0 Phosphofructokinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 464.0
TH2_k127_8120934_1 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003231 282.0
TH2_k127_8120934_2 - - - - 0.000000000000005556 87.0
TH2_k127_8120934_3 Phospholipase D Active site motif K06131 - - 0.00000000000003707 78.0
TH2_k127_8160202_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 403.0
TH2_k127_8160202_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 338.0
TH2_k127_8160202_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000002504 210.0
TH2_k127_8160202_3 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000006732 100.0
TH2_k127_8163431_0 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 301.0
TH2_k127_8163431_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000004946 185.0
TH2_k127_8163431_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000003822 154.0
TH2_k127_8163431_3 transcription factor binding - - - 0.000000008724 66.0
TH2_k127_8224476_0 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000005835 231.0
TH2_k127_8224476_1 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000002857 224.0
TH2_k127_8224476_2 protein (some members contain a von Willebrand factor type A (vWA) domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000003434 130.0
TH2_k127_8224476_3 - - - - 0.00000000000000003098 96.0
TH2_k127_8227693_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000003037 214.0
TH2_k127_8227693_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000328 97.0
TH2_k127_8227693_2 Psort location Cytoplasmic, score 7.50 - - - 0.000000000000009663 84.0
TH2_k127_8227693_3 VanZ like family - - - 0.00001763 53.0
TH2_k127_8241789_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000203 204.0
TH2_k127_8241789_1 WD40-like repeat - - - 0.00000000007673 72.0
TH2_k127_8281338_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 539.0
TH2_k127_8281338_1 23S rRNA-intervening sequence protein - - - 0.000000000000000000948 88.0
TH2_k127_8288298_0 S-adenosylmethionine-dependent methyltransferase K06969,K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.191,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 325.0
TH2_k127_8288298_1 Pseudouridine synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 295.0
TH2_k127_8288298_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004768 291.0
TH2_k127_8288298_3 COGs COG0694 Thioredoxin-like protein and domains - - - 0.00000000000000321 83.0
TH2_k127_831008_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 341.0
TH2_k127_831008_1 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 0.0000000000000000000000000000000006751 135.0
TH2_k127_831008_2 Uncharacterised nucleotidyltransferase - - - 0.000000007219 68.0
TH2_k127_8317134_0 - - - - 0.0000000000000000000000000000000000001013 164.0
TH2_k127_8322698_0 Outer membrane lipoprotein K05807 - - 0.000002418 61.0
TH2_k127_8322864_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 352.0
TH2_k127_8322864_1 probably responsible for the translocation of the substrate across the membrane K02037,K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 332.0
TH2_k127_8322864_2 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 335.0
TH2_k127_8322864_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 322.0
TH2_k127_8322864_4 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000193 220.0
TH2_k127_8322864_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000001686 99.0
TH2_k127_8322864_6 helix_turn_helix, arabinose operon control protein - - - 0.00000000172 60.0
TH2_k127_8332408_0 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000003687 59.0
TH2_k127_8332408_1 Pilus assembly protein, PilO K02664 - - 0.0002362 49.0
TH2_k127_8334137_0 polygalacturonase activity - - - 0.00000000000000000000000000000000000000000003259 183.0
TH2_k127_8334137_1 Melibiase K07407 - 3.2.1.22 0.00000000000000000000000000000000005775 149.0
TH2_k127_8334137_2 Parallel beta-helix repeats - - - 0.0000045 59.0
TH2_k127_8349753_0 Xylose operon regulatory protein K01812,K02529,K16210 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 5.3.1.12 0.00000000000000000000000000000000000000000000000000000000004464 221.0
TH2_k127_8360383_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 591.0
TH2_k127_8360383_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000003573 118.0
TH2_k127_8360383_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000001066 79.0
TH2_k127_8360383_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000002972 65.0
TH2_k127_8360383_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000002827 59.0
TH2_k127_8368184_0 beta-galactosidase activity K20844 - 3.2.1.55 0.000000000000000000000000000000000000000000000003251 199.0
TH2_k127_8368184_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000008301 79.0
TH2_k127_8368725_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 358.0
TH2_k127_8368725_1 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 340.0
TH2_k127_8368725_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000003697 91.0
TH2_k127_8368725_3 DNA methylase K07316 - 2.1.1.72 0.000005261 52.0
TH2_k127_8411735_0 Beta-galactosidase - - - 0.0000000000000296 78.0
TH2_k127_8411735_1 peptidyl-tyrosine sulfation - - - 0.000005857 59.0
TH2_k127_8420175_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.722e-242 761.0
TH2_k127_8420175_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 367.0
TH2_k127_8420175_2 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000006872 164.0
TH2_k127_8420175_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000001316 104.0
TH2_k127_8420175_4 PFAM Cyclic nucleotide-binding K10914,K21563 - - 0.000000000000000000001656 106.0
TH2_k127_8420175_5 AntiSigma factor - GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.0009916 48.0
TH2_k127_8440683_0 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 469.0
TH2_k127_8440683_1 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 360.0
TH2_k127_8490181_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 377.0
TH2_k127_8490181_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 310.0
TH2_k127_8490181_2 N-terminal domain of unknown function (DUF4140) - - - 0.0000000000000000000000000000000000000000000006851 187.0
TH2_k127_8490616_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 7.598e-285 881.0
TH2_k127_8490616_1 SMART Elongator protein 3 MiaB NifB - - - 1.393e-211 673.0
TH2_k127_8490616_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004222 276.0
TH2_k127_8490616_3 beta-1,4-mannooligosaccharide phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000003899 218.0
TH2_k127_8490616_4 Protein of unknown function (DUF433) - - - 0.0000000000006403 72.0
TH2_k127_8490616_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000001785 57.0
TH2_k127_8503959_0 Putative glutamine amidotransferase K07114 - - 0.0 1121.0
TH2_k127_8503959_1 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 521.0
TH2_k127_8503959_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002794 303.0
TH2_k127_8503959_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006952 271.0
TH2_k127_8503959_12 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 270.0
TH2_k127_8503959_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001939 238.0
TH2_k127_8503959_14 Domain of unknown function (DUF4349) - - - 0.00000000000000000000000000000000000000000000002183 178.0
TH2_k127_8503959_15 - - - - 0.000000000000000000000000000000000000000000002857 188.0
TH2_k127_8503959_16 PQQ-like domain - - - 0.0000000000000002523 93.0
TH2_k127_8503959_2 ATPase associated with K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 473.0
TH2_k127_8503959_3 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 437.0
TH2_k127_8503959_4 PFAM ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 429.0
TH2_k127_8503959_5 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 406.0
TH2_k127_8503959_6 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 341.0
TH2_k127_8503959_7 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 321.0
TH2_k127_8503959_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 327.0
TH2_k127_8503959_9 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004666 291.0
TH2_k127_8508420_0 Protein of unknown function (DUF3187) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005216 244.0
TH2_k127_8508420_1 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000004719 105.0
TH2_k127_8508420_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000383 99.0
TH2_k127_8508420_3 Anti-sigma-K factor rskA - - - 0.0005039 53.0
TH2_k127_8526603_0 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 419.0
TH2_k127_8526603_1 SGNH hydrolase-like domain, acetyltransferase AlgX K19295 - - 0.00000000000000000000000000000000000000000000000000000000002228 220.0
TH2_k127_8526603_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000002823 133.0
TH2_k127_8526603_4 - - - - 0.0001548 46.0
TH2_k127_858497_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000004202 147.0
TH2_k127_858497_1 Transporter, MotA TolQ ExbB proton channel family protein K03561 - - 0.0000000000000000001333 98.0
TH2_k127_858497_2 Biopolymer transport protein ExbD/TolR - - - 0.00005419 51.0
TH2_k127_858497_3 biopolymer transport protein K03559 - - 0.0005841 49.0
TH2_k127_8590926_0 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 304.0
TH2_k127_8590926_2 PFAM Methyltransferase type 12 - - - 0.000002502 54.0
TH2_k127_8607386_0 beta-galactosidase K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 371.0
TH2_k127_8607386_1 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000001513 55.0
TH2_k127_8625234_0 Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 1.611e-313 993.0
TH2_k127_8625234_1 PIN domain - - - 0.00000000000000000000000000000000000005538 147.0
TH2_k127_8625234_2 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000006968 78.0
TH2_k127_8634768_0 von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 437.0
TH2_k127_8634768_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006168 288.0
TH2_k127_8634768_2 TIGRFAM Small GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000005677 162.0
TH2_k127_8643503_0 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001343 277.0
TH2_k127_8643503_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000004726 147.0
TH2_k127_8643503_2 Cell division protein FtsQ K03589 - - 0.00003569 56.0
TH2_k127_864658_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 460.0
TH2_k127_864658_1 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 417.0
TH2_k127_864658_2 Glutathione peroxidase K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000587 199.0
TH2_k127_864658_3 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000001147 209.0
TH2_k127_864658_4 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000002967 165.0
TH2_k127_8658992_0 xylulokinase activity K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 610.0
TH2_k127_8658992_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001444 281.0
TH2_k127_8658992_2 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000001462 251.0
TH2_k127_8658992_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000007524 161.0
TH2_k127_8658992_4 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.0000000000009018 70.0
TH2_k127_866378_0 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000004299 173.0
TH2_k127_866378_1 binding domain protein K07138 - - 0.000000000000000004408 87.0
TH2_k127_866378_2 - - - - 0.00000000109 69.0
TH2_k127_8664255_0 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K04940 - 1.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 401.0
TH2_k127_8749960_0 - - - - 0.0002641 51.0
TH2_k127_8772765_0 geranylgeranyl reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 539.0
TH2_k127_8772765_1 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000001165 139.0
TH2_k127_8772765_2 PQQ-like domain - - - 0.000000000000007254 88.0
TH2_k127_879271_0 virion core protein, lumpy skin disease virus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 469.0
TH2_k127_879271_1 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 385.0
TH2_k127_879271_2 Toxic component of a type II toxin-antitoxin (TA) system. A sequence-specific mRNA endoribonuclease that inhibits translation elongation and induces bacterial stasis. Cleavage occurs between the second and third residue of the Lys codon followed by a G or A (5'AAA(G A)3'), is reading-frame dependent and occurs within the 5' end of most mRNAs. Ribosome-binding confers the sequence specificity and reading frame-dependence. When overexpressed in liquid media YafQ partially inhibits protein synthesis, with a reduction in growth rate and colony growth rate. This effect is counteracted by coexpression with cognate antitoxin DinJ. YafQ and DinJ together bind their own promoter, and repress its expression K19157 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006415,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032984,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034655,GO:0042221,GO:0042710,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043565,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044010,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044764,GO:0044877,GO:0046483,GO:0046677,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 - 0.000000000000000000003797 95.0
TH2_k127_879271_3 DNA-damage-inducible protein K07473 - - 0.0000000000000000001125 91.0
TH2_k127_879271_4 cobalamin binding - - - 0.000000000001173 78.0
TH2_k127_8851234_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001203 299.0
TH2_k127_8851234_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000001167 241.0
TH2_k127_8851234_2 PFAM Pyrrolo-quinoline quinone - - - 0.00000000000000000000000000000000000002346 159.0
TH2_k127_8858386_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 583.0
TH2_k127_8858386_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000001411 247.0
TH2_k127_8858386_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000003529 231.0
TH2_k127_8858386_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000001796 104.0
TH2_k127_8858386_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000001537 75.0
TH2_k127_929800_0 Higher Eukarytoes and Prokaryotes Nucleotide-binding domain - - - 0.0000000000000000000000000003201 124.0
TH2_k127_929800_1 PFAM DNA polymerase beta domain protein region - - - 0.0000000001048 70.0
TH2_k127_939828_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000001325 139.0